Run ID: 678293b6-8b7e-4595-b9ac-b2009c929f49
Sample name:
Date: 16-07-2023 20:55:53
Number of reads: 508552
Percentage reads mapped: 13.79
Median coverage: 10
Strain: La1.4
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| La1 | M.bovis | None | 1.0 |
| La1.4 | M.bovis | None | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | katG | c.402delC | Uncertain significance | |
| ethambutol | ||||
| pyrazinamide | pncA | p.His57Asp | Assoc w R | |
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | ||||
| amikacin | ||||
| kanamycin | ||||
| capreomycin | ||||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| katG | 2155709 | c.402delC | frameshift_variant | 0.14 | isoniazid | Uncertain significance | |
| pncA | 2289073 | p.His57Asp | missense_variant | 1.0 | pyrazinamide | Assoc w R |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 5752 | c.513G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5972 | p.Lys245Glu | missense_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6059 | p.Ser274Arg | missense_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6082 | p.Lys281Asn | missense_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6446 | p.Ala403Ser | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6639 | c.1405dupA | frameshift_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6785 | p.Glu516* | stop_gained | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6813 | p.His525Pro | missense_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 7202 | p.Asp655Asn | missense_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 7242 | p.Lys668Arg | missense_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7286 | c.-16T>C | upstream_gene_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7830 | p.Gly177Trp | missense_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7871 | c.570G>T | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7975 | p.Gly225Val | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8116 | p.Thr272Asn | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8181 | p.Gly294Cys | missense_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8285 | c.984C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9201 | p.Lys634Glu | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9216 | p.Asp639Asn | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| fgd1 | 491264 | p.Ser161Trp | missense_variant | 0.14 | delamanid | |
| fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | delamanid | |
| mshA | 575626 | c.279C>G | synonymous_variant | 0.17 | ethionamide | |
| isoniazid | ||||||
| mshA | 575683 | c.336G>T | synonymous_variant | 0.17 | ethionamide | |
| isoniazid | ||||||
| ccsA | 620340 | c.450C>A | synonymous_variant | 0.2 | capreomycin | |
| amikacin | ||||||
| ccsA | 620464 | p.Ala192Ser | missense_variant | 0.17 | capreomycin | |
| amikacin | ||||||
| rpoB | 759788 | c.-19A>G | upstream_gene_variant | 0.2 | rifampicin | |
| rpoB | 760040 | c.234T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 760579 | p.Lys258Thr | missense_variant | 0.2 | rifampicin | |
| rpoB | 760596 | p.Thr264Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760932 | p.Gly376Arg | missense_variant | 0.17 | rifampicin | |
| rpoB | 761352 | p.Gly516Arg | missense_variant | 0.12 | rifampicin | |
| rpoB | 762080 | c.2274G>T | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 762099 | p.Arg765Cys | missense_variant | 0.13 | rifampicin | |
| rpoB | 762459 | p.Asn885Asp | missense_variant | 0.12 | rifampicin | |
| rpoB | 762958 | p.Leu1051Arg | missense_variant | 0.15 | rifampicin | |
| rpoC | 762962 | c.-408C>T | upstream_gene_variant | 0.13 | rifampicin | |
| rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.13 | rifampicin | |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.2 | rifampicin | |
| rpoC | 763031 | c.-339T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763038 | p.Thr1078Ala | missense_variant | 0.18 | rifampicin | |
| rpoB | 763093 | p.Val1096Gly | missense_variant | 0.18 | rifampicin | |
| rpoB | 763104 | c.3299delT | frameshift_variant | 0.18 | rifampicin | |
| rpoB | 763146 | p.Ser1114Ala | missense_variant | 0.17 | rifampicin | |
| rpoB | 763251 | p.Leu1149Met | missense_variant | 0.17 | rifampicin | |
| rpoB | 763270 | c.3466dupC | frameshift_variant | 0.17 | rifampicin | |
| rpoC | 763310 | c.-60C>A | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 763494 | p.Glu42Gly | missense_variant | 0.14 | rifampicin | |
| rpoC | 763823 | p.Glu152Gln | missense_variant | 0.11 | rifampicin | |
| rpoC | 763852 | c.483_484insT | frameshift_variant | 0.14 | rifampicin | |
| rpoC | 763876 | c.507A>G | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763911 | p.Leu181Arg | missense_variant | 0.12 | rifampicin | |
| rpoC | 763960 | c.591T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 764011 | c.642T>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764445 | p.Asp359Ala | missense_variant | 0.11 | rifampicin | |
| rpoC | 764987 | p.Gln540Lys | missense_variant | 0.15 | rifampicin | |
| rpoC | 765791 | p.Thr808Ala | missense_variant | 0.11 | rifampicin | |
| rpoC | 765863 | p.Ile832Leu | missense_variant | 0.1 | rifampicin | |
| rpoC | 766400 | p.Thr1011Ala | missense_variant | 0.2 | rifampicin | |
| rpoC | 766434 | p.Glu1022Gly | missense_variant | 0.17 | rifampicin | |
| rpoC | 766593 | p.Val1075Ala | missense_variant | 0.15 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 767300 | p.Gly1311Ser | missense_variant | 0.2 | rifampicin | Uncertain significance |
| mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776130 | p.Leu784Pro | missense_variant | 0.11 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776353 | p.Ser710Pro | missense_variant | 0.1 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776506 | p.Gln659Glu | missense_variant | 0.1 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776553 | p.Gln643Arg | missense_variant | 0.2 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778377 | p.Ile35Ser | missense_variant | 0.15 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778938 | c.-458G>T | upstream_gene_variant | 0.17 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778980 | c.-75T>C | upstream_gene_variant | 0.1 | clofazimine | Uncertain significance |
| bedaquiline | ||||||
| mmpS5 | 779607 | c.-702C>A | upstream_gene_variant | 0.14 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781634 | p.Lys25Asn | missense_variant | 0.17 | streptomycin | |
| rpsL | 781693 | p.Pro45Arg | missense_variant | 0.2 | streptomycin | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.2 | linezolid | |
| rplC | 801237 | c.429G>C | synonymous_variant | 0.17 | linezolid | |
| fbiC | 1302942 | c.12T>G | synonymous_variant | 0.12 | delamanid | |
| fbiC | 1303378 | p.Arg150Ser | missense_variant | 0.12 | delamanid | |
| fbiC | 1303412 | p.Trp161* | stop_gained | 0.11 | delamanid | |
| fbiC | 1303499 | p.His190Arg | missense_variant | 0.11 | delamanid | |
| fbiC | 1303789 | p.Ile287Val | missense_variant | 0.12 | delamanid | |
| fbiC | 1304084 | p.Gly385Val | missense_variant | 0.14 | delamanid | |
| fbiC | 1304448 | c.1518C>A | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1304801 | p.Arg624Leu | missense_variant | 0.17 | delamanid | |
| fbiC | 1304976 | p.Lys682Asn | missense_variant | 0.17 | delamanid | |
| fbiC | 1305030 | c.2100G>T | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1305387 | p.Met819Ile | missense_variant | 0.14 | delamanid | |
| fbiC | 1305391 | p.Gly821Cys | missense_variant | 0.17 | delamanid | |
| Rv1258c | 1406119 | p.Gln408* | stop_gained | 0.14 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406872 | p.Gly157Ser | missense_variant | 0.12 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1407279 | p.Ala21Gly | missense_variant | 0.2 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| embR | 1416259 | c.1089G>C | synonymous_variant | 0.12 | ethambutol | |
| embR | 1416262 | c.1086G>C | synonymous_variant | 0.12 | ethambutol | |
| embR | 1416269 | p.Ala360Val | missense_variant | 0.13 | ethambutol | |
| atpE | 1460860 | c.-185C>A | upstream_gene_variant | 0.14 | bedaquiline | |
| rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471705 | n.-141A>G | upstream_gene_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471773 | n.-73G>T | upstream_gene_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471886 | n.41G>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471891 | n.46C>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471892 | n.47G>A | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471893 | n.48T>G | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471896 | n.51T>C | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472153 | n.308G>A | non_coding_transcript_exon_variant | 0.39 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472164 | n.319G>A | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472177 | n.332C>T | non_coding_transcript_exon_variant | 0.71 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472204 | n.359G>A | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472214 | n.369C>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472223 | n.378C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472240 | n.395G>C | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472242 | n.397C>T | non_coding_transcript_exon_variant | 0.71 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472251 | n.406G>T | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472252 | n.407G>A | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472253 | n.408G>T | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472256 | n.411T>A | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472259 | n.414C>A | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472277 | n.432C>G | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472349 | n.504A>C | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472374 | n.529T>G | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472382 | n.537G>A | non_coding_transcript_exon_variant | 0.52 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472389 | n.544G>A | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472390 | n.545T>A | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472391 | n.546C>T | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472412 | n.567A>C | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472484 | n.639A>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472517 | n.672T>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.45 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472537 | n.692C>T | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472541 | n.696T>G | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472545 | n.700A>T | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472553 | n.708C>T | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472572 | n.727T>C | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472574 | n.729T>C | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472579 | n.734G>A | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472582 | n.737G>A | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472583 | n.738T>A | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472584 | n.739A>G | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472594 | n.749G>C | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472596 | n.751G>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472598 | n.753A>G | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472598 | n.753A>T | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472599 | n.754G>A | non_coding_transcript_exon_variant | 0.26 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.63 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472658 | n.813G>T | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472659 | n.814G>C | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472660 | n.815T>G | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472663 | n.818_819insTGG | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472667 | n.823delG | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472707 | n.862A>G | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472714 | n.869A>C | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472715 | n.870C>G | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472716 | n.871C>A | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472719 | n.874G>A | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472733 | n.888G>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472734 | n.889C>T | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472741 | n.896G>A | non_coding_transcript_exon_variant | 0.21 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472754 | n.909G>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472848 | n.1003T>G | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472849 | n.1005delT | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472859 | n.1014G>C | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472873 | n.1028C>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472887 | n.1042G>C | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472912 | n.1067C>T | non_coding_transcript_exon_variant | 0.63 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472917 | n.1072G>A | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472953 | n.1108G>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472958 | n.1113A>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472974 | n.1129A>G | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473016 | n.1171A>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473038 | n.1193A>C | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473042 | n.1197T>C | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473044 | n.1199C>G | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473051 | n.1206T>C | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473053 | n.1208T>A | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473054 | n.1209C>G | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473061 | n.1216T>C | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473062 | n.1217T>A | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473068 | n.1223A>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473070 | n.1225G>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473071 | n.1226C>A | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473080 | n.1235C>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473081 | n.1236C>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473099 | n.1254T>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473129 | n.1284C>T | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473148 | n.1303G>A | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473163 | n.1318C>T | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473165 | n.1320C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473172 | n.1327T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473173 | n.1328C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473177 | n.1332G>A | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473191 | n.1346C>T | non_coding_transcript_exon_variant | 0.55 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473192 | n.1347A>G | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473193 | n.1348G>C | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473204 | n.1359C>G | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473205 | n.1360T>C | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473206 | n.1361G>A | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473254 | n.1409A>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473288 | n.1443C>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473310 | n.1465T>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1473537 | n.-121C>T | upstream_gene_variant | 0.14 | linezolid | |
| rrl | 1473572 | n.-86T>G | upstream_gene_variant | 0.2 | linezolid | |
| rrl | 1473690 | n.33T>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1473815 | n.158T>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474551 | n.894G>C | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474558 | n.901G>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474568 | n.911A>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474582 | n.925T>C | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| rrl | 1474583 | n.926C>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1474584 | n.927C>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1474586 | n.929T>A | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1474608 | n.951T>G | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474609 | n.952G>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474610 | n.953C>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474815 | n.1158A>G | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1474831 | n.1174A>C | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1474837 | n.1180A>G | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474843 | n.1186A>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1474844 | n.1187G>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1474866 | n.1209C>A | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1474869 | n.1212G>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474875 | n.1218G>A | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474876 | n.1219T>A | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474893 | n.1236G>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1475619 | n.1964delT | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475791 | n.2134A>G | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1475803 | n.2146T>C | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| rrl | 1475804 | n.2147G>C | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| rrl | 1475816 | n.2159C>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1475817 | n.2160A>G | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| rrl | 1475869 | n.2212C>T | non_coding_transcript_exon_variant | 0.21 | linezolid | |
| rrl | 1475874 | n.2217C>T | non_coding_transcript_exon_variant | 0.37 | linezolid | |
| rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476032 | n.2375C>G | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1476033 | n.2376T>G | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1476034 | n.2377C>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1476045 | n.2388G>A | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1476047 | n.2390G>C | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1476080 | n.2423T>A | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476103 | n.2446C>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476105 | n.2450delA | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476110 | n.2453G>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476336 | n.2679C>T | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| rrl | 1476353 | n.2696G>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1476354 | n.2697A>G | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| rrl | 1476358 | n.2701T>C | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| rrl | 1476368 | n.2711T>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1476384 | n.2727G>T | non_coding_transcript_exon_variant | 0.63 | linezolid | |
| rrl | 1476388 | n.2731T>C | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1476408 | n.2751G>A | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| rrl | 1476411 | n.2754G>A | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| rrl | 1476425 | n.2768G>A | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1476428 | n.2771C>A | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| rrl | 1476442 | n.2785T>A | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| rrl | 1476443 | n.2786G>C | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| rrl | 1476443 | n.2786G>T | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| rrl | 1476455 | n.2798C>A | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1476455 | n.2798C>G | non_coding_transcript_exon_variant | 0.55 | linezolid | |
| rrl | 1476456 | n.2799A>T | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| rrl | 1476463 | n.2806C>T | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.74 | linezolid | Uncertain significance |
| rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.66 | linezolid | |
| rrl | 1476512 | n.2855C>T | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1476524 | n.2867C>T | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476528 | n.2871A>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476529 | n.2872A>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| inhA | 1673413 | c.-789G>C | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| fabG1 | 1673597 | c.162delG | frameshift_variant | 0.14 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673936 | p.Ser166* | stop_gained | 0.17 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833538 | c.-4C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833985 | c.444G>T | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834421 | p.Gly294Trp | missense_variant | 0.17 | pyrazinamide | |
| rpsA | 1834448 | p.Lys303Glu | missense_variant | 0.12 | pyrazinamide | |
| rpsA | 1834457 | p.Pro306Thr | missense_variant | 0.11 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.17 | pyrazinamide | |
| rpsA | 1834611 | p.Arg357Gln | missense_variant | 0.14 | pyrazinamide | |
| rpsA | 1834859 | p.Ala440Thr | missense_variant | 1.0 | pyrazinamide | |
| tlyA | 1917753 | c.-187G>A | upstream_gene_variant | 0.2 | capreomycin | |
| tlyA | 1918632 | c.693G>T | synonymous_variant | 0.11 | capreomycin | |
| ndh | 2101990 | c.1053G>C | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102168 | p.Gln292Arg | missense_variant | 0.17 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102258 | p.Ser262Tyr | missense_variant | 0.2 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102635 | c.408C>T | synonymous_variant | 0.17 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102675 | p.Gln123Arg | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102938 | c.105G>C | synonymous_variant | 0.17 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103021 | p.Thr8Ala | missense_variant | 0.17 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103061 | c.-19C>A | upstream_gene_variant | 0.14 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103173 | c.-132delG | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| katG | 2153924 | p.Lys730Gln | missense_variant | 0.2 | isoniazid | |
| katG | 2153995 | p.Ala706Glu | missense_variant | 0.18 | isoniazid | |
| katG | 2154415 | p.Pro566Leu | missense_variant | 0.11 | isoniazid | Uncertain significance |
| katG | 2154500 | p.Val538Leu | missense_variant | 0.1 | isoniazid | |
| katG | 2154685 | p.Ala476Glu | missense_variant | 0.18 | isoniazid | |
| katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2154809 | p.Thr435Ala | missense_variant | 0.14 | isoniazid | |
| katG | 2155124 | p.Asn330His | missense_variant | 0.13 | isoniazid | |
| katG | 2155155 | c.957C>G | synonymous_variant | 0.13 | isoniazid | |
| katG | 2155310 | p.Gly268Cys | missense_variant | 0.15 | isoniazid | |
| katG | 2155770 | c.342C>G | synonymous_variant | 0.11 | isoniazid | |
| katG | 2156129 | c.-18A>G | upstream_gene_variant | 0.15 | isoniazid | |
| katG | 2156517 | c.-406C>A | upstream_gene_variant | 0.12 | isoniazid | Uncertain significance |
| PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| PPE35 | 2167931 | c.2682C>G | synonymous_variant | 0.17 | pyrazinamide | |
| PPE35 | 2168592 | p.Pro674Gln | missense_variant | 0.1 | pyrazinamide | |
| PPE35 | 2168599 | p.Val672Leu | missense_variant | 0.1 | pyrazinamide | Uncertain significance |
| PPE35 | 2169612 | p.Ser334Tyr | missense_variant | 0.1 | pyrazinamide | |
| Rv1979c | 2221768 | p.His466Arg | missense_variant | 0.1 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2221966 | p.Gln400Pro | missense_variant | 0.17 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2222024 | p.Ala381Ser | missense_variant | 0.13 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| pncA | 2288919 | p.Gly108Ala | missense_variant | 0.14 | pyrazinamide | |
| kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519206 | c.1092C>T | synonymous_variant | 0.2 | isoniazid | |
| kasA | 2519341 | c.1227G>C | synonymous_variant | 0.15 | isoniazid | |
| eis | 2714199 | p.Lys378Asn | missense_variant | 0.12 | kanamycin | |
| amikacin | ||||||
| eis | 2714374 | c.958delG | frameshift_variant | 0.17 | kanamycin | |
| amikacin | ||||||
| eis | 2714837 | p.Val166Leu | missense_variant | 0.2 | kanamycin | |
| amikacin | ||||||
| eis | 2714849 | p.Ser162Gly | missense_variant | 0.18 | kanamycin | |
| amikacin | ||||||
| eis | 2715320 | p.Leu5Met | missense_variant | 0.12 | kanamycin | |
| amikacin | ||||||
| ahpC | 2726147 | c.-46A>C | upstream_gene_variant | 0.14 | isoniazid | |
| ahpC | 2726250 | p.Gly20Arg | missense_variant | 0.2 | isoniazid | |
| ahpC | 2726269 | p.Val26Gly | missense_variant | 0.2 | isoniazid | |
| ahpC | 2726515 | p.Phe108Cys | missense_variant | 0.2 | isoniazid | |
| ahpC | 2726636 | c.444G>C | synonymous_variant | 0.13 | isoniazid | |
| folC | 2746470 | p.Gly377Arg | missense_variant | 0.12 | para-aminosalicylic_acid | |
| folC | 2747148 | p.Lys151Gln | missense_variant | 0.18 | para-aminosalicylic_acid | |
| pepQ | 2860029 | c.390A>C | synonymous_variant | 0.11 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860104 | p.Asp105Glu | missense_variant | 0.15 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860143 | c.276G>T | synonymous_variant | 0.2 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860187 | p.Ala78Pro | missense_variant | 0.17 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860233 | c.186T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| ribD | 2987099 | c.261C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
| ribD | 2987199 | p.Thr121Ala | missense_variant | 0.14 | para-aminosalicylic_acid | |
| ribD | 2987287 | p.Asp150Ala | missense_variant | 0.13 | para-aminosalicylic_acid | |
| ribD | 2987297 | c.459C>A | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
| ribD | 2987441 | c.603A>G | synonymous_variant | 0.14 | para-aminosalicylic_acid | |
| ribD | 2987468 | p.Glu210Asp | missense_variant | 0.14 | para-aminosalicylic_acid | |
| ribD | 2987502 | p.Gly222Ser | missense_variant | 0.17 | para-aminosalicylic_acid | |
| ribD | 2987602 | p.Tyr255Cys | missense_variant | 0.14 | para-aminosalicylic_acid | |
| Rv2752c | 3064712 | p.Ser494Pro | missense_variant | 0.17 | rifampicin | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3064852 | p.Met447Arg | missense_variant | 0.11 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3064912 | p.Val427Gly | missense_variant | 0.11 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3064924 | p.Ala423Val | missense_variant | 0.12 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065532 | c.660A>G | synonymous_variant | 0.11 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065536 | p.Gly219Val | missense_variant | 0.12 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065692 | p.His167Arg | missense_variant | 0.2 | rifampicin | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| thyX | 3067471 | p.Asn159His | missense_variant | 0.2 | para-aminosalicylic_acid | |
| thyX | 3067767 | p.Tyr60Cys | missense_variant | 0.15 | para-aminosalicylic_acid | |
| thyX | 3068070 | c.-125T>G | upstream_gene_variant | 0.13 | para-aminosalicylic_acid | |
| thyA | 3074279 | p.Gly65Cys | missense_variant | 0.17 | para-aminosalicylic_acid | |
| ald | 3087084 | c.266delA | frameshift_variant | 1.0 | cycloserine | |
| ald | 3087153 | p.Thr112Ser | missense_variant | 0.13 | cycloserine | |
| ald | 3087618 | p.Ile267Leu | missense_variant | 0.11 | cycloserine | |
| ald | 3087653 | c.834A>G | synonymous_variant | 0.12 | cycloserine | |
| ald | 3087831 | p.Ala338Thr | missense_variant | 0.12 | cycloserine | |
| fbiD | 3339085 | c.-33T>C | upstream_gene_variant | 0.2 | delamanid | |
| fbiD | 3339433 | p.Gly106Trp | missense_variant | 0.15 | delamanid | |
| Rv3083 | 3449134 | p.Gln211Lys | missense_variant | 0.15 | ethionamide | |
| Rv3083 | 3449434 | p.Ser311Pro | missense_variant | 1.0 | ethionamide | |
| fprA | 3473998 | c.-9G>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| fprA | 3473998 | c.-10_-9insA | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| fprA | 3474179 | p.Pro58His | missense_variant | 0.17 | capreomycin | |
| amikacin | ||||||
| fprA | 3474224 | c.223delC | frameshift_variant | 0.17 | capreomycin | |
| amikacin | ||||||
| fprA | 3474427 | p.Val141Ile | missense_variant | 1.0 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| fprA | 3474651 | c.645G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| fprA | 3474823 | p.Thr273Ala | missense_variant | 0.17 | capreomycin | |
| amikacin | ||||||
| fprA | 3475126 | p.Asp374His | missense_variant | 0.2 | capreomycin | |
| amikacin | ||||||
| fprA | 3475159 | p.Asn385Asp | missense_variant | 1.0 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| fprA | 3475250 | p.Pro415Leu | missense_variant | 0.18 | capreomycin | |
| amikacin | ||||||
| fprA | 3475269 | c.1263C>A | synonymous_variant | 0.17 | capreomycin | |
| amikacin | ||||||
| fprA | 3475326 | c.1320C>A | synonymous_variant | 0.18 | capreomycin | |
| amikacin | ||||||
| whiB7 | 3568571 | p.Glu37Lys | missense_variant | 0.14 | streptomycin | |
| kanamycin | ||||||
| amikacin | ||||||
| Rv3236c | 3612261 | p.Lys286Gln | missense_variant | 0.17 | pyrazinamide | |
| Rv3236c | 3612320 | p.Leu266Arg | missense_variant | 0.17 | pyrazinamide | |
| Rv3236c | 3613100 | c.16delG | frameshift_variant | 0.18 | pyrazinamide | |
| fbiA | 3640656 | p.Asp38Glu | missense_variant | 0.12 | delamanid | |
| fbiA | 3640672 | p.Val44Phe | missense_variant | 0.13 | delamanid | |
| fbiB | 3641286 | c.-249C>A | upstream_gene_variant | 0.2 | delamanid | |
| fbiA | 3641333 | p.Gly264Val | missense_variant | 0.12 | delamanid | |
| fbiB | 3641526 | c.-9A>G | upstream_gene_variant | 0.12 | delamanid | |
| fbiB | 3641557 | p.Ser8Tyr | missense_variant | 0.14 | delamanid | |
| fbiB | 3641581 | p.Pro16Leu | missense_variant | 0.12 | delamanid | |
| fbiB | 3642529 | p.Glu332Gly | missense_variant | 0.17 | delamanid | |
| alr | 3840318 | p.Pro368Leu | missense_variant | 0.18 | cycloserine | |
| alr | 3840830 | p.Met197Ile | missense_variant | 0.15 | cycloserine | |
| alr | 3840940 | p.Gly161Trp | missense_variant | 0.2 | cycloserine | |
| alr | 3841010 | p.Gln137His | missense_variant | 0.11 | cycloserine | |
| alr | 3841045 | p.Ala126Ser | missense_variant | 0.1 | cycloserine | |
| rpoA | 3877694 | p.Val272Met | missense_variant | 0.14 | rifampicin | |
| rpoA | 3877697 | p.Thr271Pro | missense_variant | 0.12 | rifampicin | |
| rpoA | 3877721 | p.Cys263Arg | missense_variant | 0.2 | rifampicin | |
| rpoA | 3877754 | p.Asp252His | missense_variant | 0.12 | rifampicin | |
| rpoA | 3877768 | p.Phe247Ser | missense_variant | 0.1 | rifampicin | |
| rpoA | 3878222 | p.Tyr96His | missense_variant | 0.1 | rifampicin | |
| rpoA | 3878255 | p.Val85Leu | missense_variant | 0.11 | rifampicin | Uncertain significance |
| clpC1 | 4038270 | p.Pro812His | missense_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038738 | p.Asp656Gly | missense_variant | 0.2 | pyrazinamide | |
| clpC1 | 4038969 | p.Gln579Pro | missense_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039889 | c.816G>T | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039925 | c.780C>T | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039940 | c.765G>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>G | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039949 | c.756G>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039955 | c.750G>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039964 | c.741C>G | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4039982 | c.723G>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4040002 | p.His235Asn | missense_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040003 | c.702G>C | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040009 | c.696C>A | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040015 | c.690G>T | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040030 | c.675C>G | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>T | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4040042 | c.663C>T | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4040047 | p.Val220Phe | missense_variant | 0.13 | pyrazinamide | |
| clpC1 | 4040547 | p.Gly53Ala | missense_variant | 0.14 | pyrazinamide | |
| clpC1 | 4040608 | p.Ile33Leu | missense_variant | 0.2 | pyrazinamide | |
| panD | 4044036 | c.246G>T | synonymous_variant | 0.2 | pyrazinamide | |
| panD | 4044218 | p.Tyr22His | missense_variant | 0.17 | pyrazinamide | |
| embC | 4240755 | p.Leu298Pro | missense_variant | 0.18 | ethambutol | |
| embC | 4241737 | c.1875G>T | synonymous_variant | 0.13 | ethambutol | |
| embC | 4241780 | p.Trp640Gly | missense_variant | 0.11 | ethambutol | |
| embC | 4241861 | p.Glu667Lys | missense_variant | 0.14 | ethambutol | |
| embC | 4241893 | c.2031A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4243227 | c.-6A>T | upstream_gene_variant | 0.2 | ethambutol | |
| embA | 4243785 | p.Leu185Met | missense_variant | 0.15 | ethambutol | |
| embA | 4243818 | p.Ile196Leu | missense_variant | 0.18 | ethambutol | |
| embA | 4244417 | c.1185G>A | synonymous_variant | 0.2 | ethambutol | |
| embA | 4244633 | c.1401C>G | synonymous_variant | 0.17 | ethambutol | |
| embA | 4244698 | p.Val489Ala | missense_variant | 0.11 | ethambutol | |
| embA | 4244704 | p.Pro491Gln | missense_variant | 0.14 | ethambutol | |
| embA | 4244768 | p.Glu512Asp | missense_variant | 0.17 | ethambutol | |
| embA | 4245003 | p.Thr591Ala | missense_variant | 0.18 | ethambutol | Uncertain significance |
| embA | 4245169 | p.Val646Ala | missense_variant | 0.2 | ethambutol | |
| embA | 4245426 | p.Ser732Gly | missense_variant | 0.2 | ethambutol | |
| embA | 4246125 | p.Glu965* | stop_gained | 0.17 | ethambutol | |
| embA | 4246329 | p.Thr1033Pro | missense_variant | 0.12 | ethambutol | |
| embB | 4246864 | c.351C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4246879 | c.366C>T | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247184 | p.Gly224Val | missense_variant | 0.2 | ethambutol | |
| embB | 4247727 | p.Glu405Gly | missense_variant | 0.12 | ethambutol | |
| embB | 4247771 | p.Glu420Gln | missense_variant | 0.12 | ethambutol | |
| embB | 4248989 | p.Ile826Leu | missense_variant | 0.15 | ethambutol | |
| embB | 4249115 | p.Pro868Thr | missense_variant | 0.2 | ethambutol | |
| embB | 4249552 | c.3039C>T | synonymous_variant | 0.17 | ethambutol | |
| embB | 4249723 | c.3210G>T | synonymous_variant | 0.2 | ethambutol | |
| aftB | 4267153 | p.Ala562Pro | missense_variant | 0.17 | capreomycin | |
| amikacin | ||||||
| aftB | 4267284 | p.Thr518Asn | missense_variant | 0.12 | capreomycin | |
| amikacin | ||||||
| aftB | 4267300 | p.Pro513Ser | missense_variant | 1.0 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| aftB | 4267696 | p.Gly381Trp | missense_variant | 0.17 | capreomycin | |
| amikacin | ||||||
| aftB | 4268040 | p.Leu266Pro | missense_variant | 0.11 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| aftB | 4269351 | c.-515C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| ubiA | 4269756 | p.Trp26Cys | missense_variant | 0.2 | ethambutol | |
| ethA | 4326133 | c.1341C>A | synonymous_variant | 0.2 | ethionamide | |
| ethA | 4326155 | p.Leu440Pro | missense_variant | 0.17 | ethionamide | Uncertain significance |
| ethA | 4326232 | c.1242T>C | synonymous_variant | 0.12 | ethionamide | |
| ethA | 4326239 | p.Asn412Ser | missense_variant | 0.12 | ethionamide | |
| ethA | 4326369 | p.Tyr369His | missense_variant | 0.2 | ethionamide | |
| ethA | 4326400 | c.1074A>G | synonymous_variant | 0.14 | ethionamide | |
| ethA | 4326528 | p.Thr316Pro | missense_variant | 0.17 | ethionamide | |
| ethA | 4326810 | p.Ala222Pro | missense_variant | 0.13 | ethionamide | |
| ethA | 4328280 | c.-807A>G | upstream_gene_variant | 0.11 | ethionamide | |
| whiB6 | 4338174 | c.348A>C | synonymous_variant | 0.18 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338208 | p.Pro105Gln | missense_variant | 0.12 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| whiB6 | 4338318 | p.Glu68Asp | missense_variant | 0.1 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338346 | p.Arg59Leu | missense_variant | 0.17 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| whiB6 | 4338578 | c.-57C>T | upstream_gene_variant | 0.2 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338585 | c.-64G>T | upstream_gene_variant | 0.2 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| gid | 4407719 | p.Ile162Leu | missense_variant | 0.12 | streptomycin | |
| gid | 4407734 | p.Gly157Trp | missense_variant | 0.14 | streptomycin | |
| gid | 4407854 | p.Gly117Trp | missense_variant | 0.2 | streptomycin | |
| gid | 4407855 | c.348G>T | synonymous_variant | 0.2 | streptomycin | |
| gid | 4408064 | p.Arg47Gly | missense_variant | 0.15 | streptomycin | |
| gid | 4408202 | c.1A>C | initiator_codon_variant | 0.15 | streptomycin | |
| gid | 4408213 | c.-11C>T | upstream_gene_variant | 0.15 | streptomycin | Uncertain significance |
| gid | 4408347 | c.-145T>G | upstream_gene_variant | 0.17 | streptomycin |
