TB-Profiler result

Run: SRR13861332
Summary

Run ID: SRR13861332

Sample name:

Date: 03-04-2023 09:29:12

Number of reads: 1752208

Percentage reads mapped: 43.85

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.97
lineage4.9 Euro-American (H37Rv-like) T1 None 0.97
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.16 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5258 p.Lys7* stop_gained 1.0
gyrB 7122 c.1883_1884insA frameshift_variant 1.0
gyrA 7523 c.222C>G synonymous_variant 0.15
gyrA 7532 c.231T>C synonymous_variant 0.15
gyrA 7541 c.240C>G synonymous_variant 0.15
gyrA 7571 c.270G>C synonymous_variant 0.16
gyrA 7585 p.Ser95Thr missense_variant 0.14
gyrA 7595 c.294C>G synonymous_variant 0.15
gyrA 7607 c.306C>G synonymous_variant 0.2
gyrA 7626 c.325C>T synonymous_variant 0.22
gyrA 7631 c.330G>C synonymous_variant 0.22
gyrA 7637 c.336C>G synonymous_variant 0.22
gyrA 7649 c.348C>T synonymous_variant 0.18
gyrA 7652 c.351C>T synonymous_variant 0.17
gyrA 7658 c.357A>G synonymous_variant 0.19
gyrA 7664 c.363T>C synonymous_variant 0.18
gyrA 7670 c.369A>G synonymous_variant 0.19
gyrA 7676 c.375G>C synonymous_variant 0.21
gyrA 7683 c.382A>C synonymous_variant 0.19
gyrA 7694 c.393A>G synonymous_variant 0.19
gyrA 7697 c.396C>G synonymous_variant 0.19
gyrA 7710 c.409T>C synonymous_variant 0.2
gyrA 7715 c.414G>C synonymous_variant 0.19
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.17
gyrA 7763 c.462T>C synonymous_variant 0.14
gyrA 8111 c.810G>C synonymous_variant 0.14
gyrA 8156 c.855T>C synonymous_variant 0.16
gyrA 8204 c.903C>T synonymous_variant 0.14
gyrA 8216 c.915G>A synonymous_variant 0.14
gyrA 8225 c.924T>C synonymous_variant 0.15
gyrA 8234 c.933T>G synonymous_variant 0.14
gyrA 8237 c.936A>G synonymous_variant 0.15
gyrA 8253 p.Ile318Leu missense_variant 0.18
gyrA 8264 c.963T>C synonymous_variant 0.15
gyrA 8267 c.966G>C synonymous_variant 0.15
gyrA 8270 c.969G>C synonymous_variant 0.16
gyrA 8324 c.1023T>C synonymous_variant 0.17
gyrA 8339 c.1038A>G synonymous_variant 0.16
gyrA 8342 c.1041G>C synonymous_variant 0.16
gyrA 8366 c.1065G>C synonymous_variant 0.18
gyrA 8375 c.1074G>C synonymous_variant 0.17
gyrA 8399 c.1098T>C synonymous_variant 0.15
gyrA 8903 c.1602T>C synonymous_variant 0.15
gyrA 8915 c.1614A>G synonymous_variant 0.17
gyrA 8987 c.1686C>G synonymous_variant 0.14
gyrA 8990 c.1689C>G synonymous_variant 0.14
fgd1 491502 c.720G>A synonymous_variant 0.15
fgd1 491508 c.726A>G synonymous_variant 0.16
fgd1 491509 c.727T>C synonymous_variant 0.16
fgd1 491512 p.Asn244Glu missense_variant 0.15
fgd1 491550 c.768T>C synonymous_variant 0.15
mshA 575623 c.276C>G synonymous_variant 0.17
mshA 575629 c.282A>C synonymous_variant 0.16
mshA 575635 c.288A>C synonymous_variant 0.16
mshA 575638 c.291T>C synonymous_variant 0.16
mshA 575641 c.294A>G synonymous_variant 0.16
mshA 575648 p.Val101Gln missense_variant 0.17
mshA 575659 c.312A>G synonymous_variant 0.2
mshA 575665 c.318G>C synonymous_variant 0.2
mshA 575689 c.342G>C synonymous_variant 0.15
mshA 575695 c.348C>G synonymous_variant 0.17
mshA 575704 c.357T>C synonymous_variant 0.17
mshA 575705 c.358T>C synonymous_variant 0.17
mshA 575713 c.366G>A synonymous_variant 0.2
mshA 575719 c.372C>T synonymous_variant 0.23
mshA 575734 c.387T>G synonymous_variant 0.23
mshA 575737 c.390T>C synonymous_variant 0.22
mshA 575746 c.399C>G synonymous_variant 0.22
mshA 575752 c.405G>A synonymous_variant 0.19
mshA 575767 c.420G>A synonymous_variant 0.16
mshA 575771 p.Val142Ser missense_variant 0.16
mshA 575779 c.432A>G synonymous_variant 0.17
ccsA 620646 c.756G>A synonymous_variant 0.15
ccsA 620661 c.771C>G synonymous_variant 0.15
ccsA 620703 c.813G>C synonymous_variant 0.17
ccsA 620710 p.Val274Ile missense_variant 0.15
ccsA 620730 c.840C>T synonymous_variant 0.14
ccsA 620734 c.844C>A synonymous_variant 0.14
rpoB 760196 c.390C>G synonymous_variant 0.15
rpoB 760235 c.429T>C synonymous_variant 0.14
rpoB 760307 c.501T>C synonymous_variant 0.15
rpoB 760406 c.600G>C synonymous_variant 0.19
rpoB 760418 c.612G>C synonymous_variant 0.18
rpoB 760982 c.1176G>C synonymous_variant 0.14
rpoB 760985 c.1179G>C synonymous_variant 0.16
rpoB 761015 c.1209G>C synonymous_variant 0.16
rpoB 761021 c.1215G>C synonymous_variant 0.19
rpoB 761027 c.1221A>G synonymous_variant 0.17
rpoB 761036 c.1230G>C synonymous_variant 0.15
rpoB 761051 c.1245G>T synonymous_variant 0.17
rpoB 761054 c.1248G>C synonymous_variant 0.16
rpoB 761057 c.1251G>C synonymous_variant 0.16
rpoB 761060 c.1254C>G synonymous_variant 0.15
rpoB 761063 c.1257C>G synonymous_variant 0.15
rpoB 761094 c.1288C>T synonymous_variant 0.15
rpoB 761150 c.1344A>C synonymous_variant 0.14
rpoB 761183 c.1377T>G synonymous_variant 0.14
rpoB 761222 c.1416G>C synonymous_variant 0.15
rpoB 761261 c.1455G>T synonymous_variant 0.14
rpoB 762083 c.2277T>C synonymous_variant 0.14
rpoB 762101 c.2295C>G synonymous_variant 0.14
rpoB 762131 c.2325C>G synonymous_variant 0.15
rpoB 762143 c.2337T>C synonymous_variant 0.15
rpoB 762149 c.2343G>C synonymous_variant 0.16
rpoB 762167 c.2361T>C synonymous_variant 0.19
rpoB 762176 c.2370T>C synonymous_variant 0.21
rpoB 762185 c.2379G>C synonymous_variant 0.18
rpoB 762218 c.2412T>G synonymous_variant 0.17
rpoB 762254 c.2448T>C synonymous_variant 0.2
rpoB 762266 c.2460T>C synonymous_variant 0.2
rpoB 762284 c.2478G>C synonymous_variant 0.21
rpoB 762293 c.2487T>C synonymous_variant 0.23
rpoB 762317 c.2511A>G synonymous_variant 0.21
rpoB 762329 c.2523G>C synonymous_variant 0.19
rpoB 762338 c.2532T>C synonymous_variant 0.17
rpoB 762347 c.2541T>C synonymous_variant 0.18
rpoB 762362 p.Glu852Asp missense_variant 0.16
rpoB 762369 c.2563T>C synonymous_variant 0.16
rpoC 762374 c.-996G>C upstream_gene_variant 0.17
rpoC 762380 c.-990T>G upstream_gene_variant 0.18
rpoC 762395 c.-975G>C upstream_gene_variant 0.16
rpoC 762398 c.-972T>C upstream_gene_variant 0.17
rpoC 762401 c.-969G>C upstream_gene_variant 0.16
rpoC 762404 c.-966T>C upstream_gene_variant 0.16
rpoC 762410 c.-960T>C upstream_gene_variant 0.15
rpoC 762416 c.-954A>G upstream_gene_variant 0.15
rpoC 762443 c.-927G>C upstream_gene_variant 0.16
rpoC 762989 c.-381G>C upstream_gene_variant 0.15
rpoC 763028 c.-342T>C upstream_gene_variant 0.16
rpoC 763031 c.-339T>G upstream_gene_variant 0.15
rpoC 763034 c.-336C>G upstream_gene_variant 0.15
rpoC 763040 c.-330C>G upstream_gene_variant 0.16
rpoC 763070 c.-300T>C upstream_gene_variant 0.15
rpoC 763486 c.117T>C synonymous_variant 0.15
rpoC 763528 c.159G>A synonymous_variant 0.17
rpoC 763546 c.177A>G synonymous_variant 0.16
rpoC 763594 c.225C>T synonymous_variant 0.14
rpoC 763633 c.264T>C synonymous_variant 0.14
rpoC 763636 c.267T>C synonymous_variant 0.14
rpoC 763642 c.273G>C synonymous_variant 0.17
rpoC 763658 p.Leu97Phe missense_variant 0.15
rpoC 763967 p.Gly200Ser missense_variant 0.13
rpoC 764131 c.762T>C synonymous_variant 0.15
rpoC 764196 p.Ser276* stop_gained 0.13
rpoC 765404 p.Leu679Val missense_variant 0.15
rpoC 765421 c.2052C>G synonymous_variant 0.13
rpoC 765451 c.2082C>G synonymous_variant 0.18
rpoC 765452 p.Ala695Ser missense_variant 0.18
rpoC 765478 c.2109T>C synonymous_variant 0.22
rpoC 765499 c.2130C>G synonymous_variant 0.22
rpoC 765508 c.2139C>G synonymous_variant 0.23
rpoC 765541 c.2172C>G synonymous_variant 0.21
rpoC 765553 c.2184C>T synonymous_variant 0.2
rpoC 765556 c.2187G>C synonymous_variant 0.2
rpoC 765559 c.2190G>C synonymous_variant 0.2
rpoC 765578 c.2209C>T synonymous_variant 0.18
rpoC 765583 c.2214G>T synonymous_variant 0.18
rpoC 765613 p.His748Gln missense_variant 0.17
rpoC 765625 c.2256C>G synonymous_variant 0.18
rpoC 765628 c.2259G>C synonymous_variant 0.18
rpoC 765631 p.Asp754Glu missense_variant 0.17
rpoC 765658 c.2289C>T synonymous_variant 0.16
rpoC 765967 c.2598C>T synonymous_variant 0.13
rpoC 765970 c.2601C>T synonymous_variant 0.13
rpoC 765985 c.2616C>T synonymous_variant 0.14
rpoC 765994 c.2625A>T synonymous_variant 0.15
rpoC 766309 c.2940G>C synonymous_variant 0.15
rpoC 766312 c.2943T>G synonymous_variant 0.15
rpoC 766315 c.2946C>G synonymous_variant 0.15
rpoC 766327 c.2958C>G synonymous_variant 0.17
rpoC 766345 c.2976T>C synonymous_variant 0.18
rpoC 766348 c.2979A>G synonymous_variant 0.18
rpoC 766363 c.2994G>C synonymous_variant 0.18
rpoC 766381 c.3012C>T synonymous_variant 0.22
rpoC 766384 c.3015A>G synonymous_variant 0.23
rpoC 766390 c.3021C>T synonymous_variant 0.23
rpoC 766408 c.3039C>T synonymous_variant 0.24
rpoC 766426 c.3057C>T synonymous_variant 0.27
rpoC 766447 c.3078T>C synonymous_variant 0.24
rpoC 766483 c.3114G>C synonymous_variant 0.2
rpoC 766484 p.Val1039Ile missense_variant 0.2
rpoC 766492 c.3123T>C synonymous_variant 0.2
rpoC 766495 c.3126C>T synonymous_variant 0.2
rpoC 766522 c.3153C>G synonymous_variant 0.2
rpoC 766528 c.3159T>C synonymous_variant 0.17
rpoC 766531 c.3162G>T synonymous_variant 0.18
rpoC 766543 c.3174C>T synonymous_variant 0.18
rpoC 766549 c.3180G>C synonymous_variant 0.18
rpoC 766801 c.3432C>A synonymous_variant 0.13
rpoC 766843 c.3474T>C synonymous_variant 0.14
rpoC 766861 c.3492G>C synonymous_variant 0.14
rpoC 766933 c.3564A>G synonymous_variant 0.15
rpoC 767062 c.3693C>A synonymous_variant 0.14
rpoC 767098 c.3729T>C synonymous_variant 0.15
rpoC 767119 c.3750A>G synonymous_variant 0.17
rpoC 767134 c.3765C>G synonymous_variant 0.15
rpoC 767158 c.3789T>C synonymous_variant 0.16
rpoC 767167 c.3798C>G synonymous_variant 0.16
mmpL5 776374 p.Arg703Cys missense_variant 1.0
mmpR5 779126 p.Cys46Phe missense_variant 1.0
rpsL 781859 c.300T>C synonymous_variant 0.15
rpsL 781868 c.309T>C synonymous_variant 0.15
rpsL 781898 c.339A>T synonymous_variant 0.13
rplC 800612 c.-197A>G upstream_gene_variant 0.22
rplC 800618 c.-191T>C upstream_gene_variant 0.24
rplC 800648 c.-161A>C upstream_gene_variant 0.2
rplC 800654 c.-155T>C upstream_gene_variant 0.2
rplC 801447 p.Lys213Asn missense_variant 0.97
fbiC 1303004 p.Ala25Glu missense_variant 1.0
fbiC 1303171 p.Arg81Trp missense_variant 1.0
fbiC 1303517 p.Met196Thr missense_variant 0.94
fbiC 1303818 c.888C>G synonymous_variant 0.19
fbiC 1303836 c.906G>C synonymous_variant 0.18
fbiC 1303845 c.915C>G synonymous_variant 0.17
fbiC 1303846 p.Phe306Val missense_variant 0.17
fbiC 1303854 c.924T>C synonymous_variant 0.18
fbiC 1303860 c.930A>C synonymous_variant 0.17
fbiC 1303881 c.951G>C synonymous_variant 0.2
fbiC 1303884 c.954T>G synonymous_variant 0.18
fbiC 1303911 c.981G>C synonymous_variant 0.2
fbiC 1303914 c.984C>G synonymous_variant 0.18
fbiC 1303920 c.990C>G synonymous_variant 0.18
fbiC 1303923 c.993C>T synonymous_variant 0.17
fbiC 1303929 c.999G>C synonymous_variant 0.17
fbiC 1303947 c.1017T>C synonymous_variant 0.15
fbiC 1303948 p.Gly340Arg missense_variant 0.15
fbiC 1303995 c.1065C>T synonymous_variant 0.16
fbiC 1304001 c.1071C>G synonymous_variant 0.16
fbiC 1304008 c.1078T>C synonymous_variant 0.16
fbiC 1304034 c.1104A>G synonymous_variant 0.14
fbiC 1304040 c.1110C>G synonymous_variant 0.15
fbiC 1304694 c.1764A>C synonymous_variant 0.15
fbiC 1304703 c.1773C>G synonymous_variant 0.17
fbiC 1304715 c.1785G>C synonymous_variant 0.17
fbiC 1304724 c.1794A>G synonymous_variant 0.18
fbiC 1304727 c.1797A>G synonymous_variant 0.17
fbiC 1304742 c.1812T>C synonymous_variant 0.16
fbiC 1305311 p.Arg794Gln missense_variant 0.13
fbiC 1305331 p.Glu801Lys missense_variant 0.14
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.13
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.16
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.16
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.13
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.16
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.16
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.14
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.16
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.16
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.15
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.16
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.17
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.14
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.2
rrl 1474959 n.1302C>T non_coding_transcript_exon_variant 0.2
rrl 1474962 n.1306delG non_coding_transcript_exon_variant 0.21
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.2
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 0.24
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.22
rrl 1475015 n.1358C>T non_coding_transcript_exon_variant 0.22
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.23
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.22
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.16
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.17
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.17
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.17
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.15
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.15
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.17
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.16
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.15
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.16
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.15
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.18
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.16
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.14
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.2
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.27
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.27
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.27
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.29
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.32
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.3
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.31
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.31
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.31
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.29
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.29
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.28
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.27
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.26
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.27
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.24
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.24
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.23
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.24
rpsA 1833841 c.300C>G synonymous_variant 0.14
rpsA 1833847 c.306C>G synonymous_variant 0.15
rpsA 1833856 c.315A>G synonymous_variant 0.17
rpsA 1833862 c.321G>T synonymous_variant 0.16
rpsA 1833874 c.333T>C synonymous_variant 0.17
rpsA 1833928 c.387G>C synonymous_variant 0.15
rpsA 1833940 c.399C>G synonymous_variant 0.18
rpsA 1833970 c.429G>C synonymous_variant 0.18
rpsA 1833979 c.438T>C synonymous_variant 0.17
rpsA 1834396 c.855G>C synonymous_variant 0.14
rpsA 1834417 c.876G>C synonymous_variant 0.16
rpsA 1834423 c.882G>C synonymous_variant 0.15
rpsA 1834474 c.933C>G synonymous_variant 0.16
rpsA 1834489 c.948T>C synonymous_variant 0.16
rpsA 1834498 c.957C>T synonymous_variant 0.17
rpsA 1834528 c.987T>C synonymous_variant 0.19
rpsA 1834546 c.1005T>C synonymous_variant 0.19
rpsA 1834555 c.1014T>C synonymous_variant 0.19
rpsA 1834558 c.1017C>G synonymous_variant 0.21
rpsA 1834606 c.1065C>G synonymous_variant 0.22
rpsA 1834609 c.1068T>C synonymous_variant 0.2
rpsA 1834622 p.Ser361Thr missense_variant 0.15
rpsA 1834633 c.1092A>G synonymous_variant 0.16
rpsA 1834639 c.1098T>C synonymous_variant 0.21
rpsA 1834640 p.Glu367* stop_gained 0.79
rpsA 1834666 c.1125G>C synonymous_variant 0.21
rpsA 1834669 c.1128G>C synonymous_variant 0.22
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.19
rpsA 1834732 c.1191T>C synonymous_variant 0.17
rpsA 1834733 p.Ala398Pro missense_variant 0.17
ndh 2103004 c.39T>G synonymous_variant 1.0
PPE35 2170453 p.Gly54Ser missense_variant 1.0
Rv1979c 2223326 c.-162C>T upstream_gene_variant 1.0
pncA 2288748 p.Ala165Asp missense_variant 1.0
kasA 2518474 p.Glu120Asp missense_variant 0.95
kasA 2518504 c.390T>C synonymous_variant 0.15
kasA 2518506 p.Ala131Glu missense_variant 0.15
kasA 2518513 c.399C>G synonymous_variant 0.17
kasA 2518519 c.405G>C synonymous_variant 0.16
kasA 2518528 c.414C>G synonymous_variant 0.17
kasA 2518540 c.426T>G synonymous_variant 0.17
kasA 2518561 c.447T>C synonymous_variant 0.18
kasA 2518567 c.453G>C synonymous_variant 0.18
kasA 2518570 c.456G>C synonymous_variant 0.17
kasA 2518574 p.Ile154Val missense_variant 0.17
kasA 2518588 c.474T>C synonymous_variant 0.19
kasA 2518591 c.477G>C synonymous_variant 0.19
kasA 2518609 p.Met165Ile missense_variant 0.2
kasA 2518621 c.507G>A synonymous_variant 0.19
kasA 2518663 c.549T>C synonymous_variant 0.15
kasA 2518672 c.558G>C synonymous_variant 0.16
kasA 2518687 c.573C>T synonymous_variant 0.15
kasA 2518696 c.582C>G synonymous_variant 0.17
kasA 2518702 c.588C>T synonymous_variant 0.17
kasA 2518711 c.597A>G synonymous_variant 0.18
kasA 2518714 c.600A>C synonymous_variant 0.18
kasA 2518717 c.603C>T synonymous_variant 0.19
kasA 2518723 p.Glu203Asp missense_variant 0.18
kasA 2518732 c.618C>G synonymous_variant 0.18
kasA 2518741 c.627G>C synonymous_variant 0.19
kasA 2518747 c.633C>G synonymous_variant 0.19
kasA 2518768 c.654C>G synonymous_variant 0.18
kasA 2518783 c.669T>C synonymous_variant 0.16
kasA 2518792 c.678C>G synonymous_variant 0.16
kasA 2518795 c.681C>G synonymous_variant 0.15
Rv2752c 3066024 c.168T>C synonymous_variant 0.17
thyX 3067244 c.702C>G synonymous_variant 0.15
thyX 3067250 p.Val232Ile missense_variant 0.15
thyX 3067277 c.669C>G synonymous_variant 0.16
thyX 3067280 c.666G>C synonymous_variant 0.15
thyX 3067284 p.Ala221Asp missense_variant 0.15
thyX 3067293 p.Gln218Arg missense_variant 0.14
thyX 3067304 c.642A>G synonymous_variant 0.15
thyX 3067316 c.630A>G synonymous_variant 0.14
thyX 3067355 c.591A>C synonymous_variant 0.16
thyX 3067529 c.417C>G synonymous_variant 0.88
thyX 3067619 c.327A>C synonymous_variant 0.14
thyX 3067661 c.285C>G synonymous_variant 0.15
thyX 3067688 c.258G>C synonymous_variant 0.15
thyX 3067694 c.252G>C synonymous_variant 0.15
thyX 3067718 c.228C>G synonymous_variant 0.19
thyX 3067721 c.225T>C synonymous_variant 0.19
thyX 3067724 c.222G>A synonymous_variant 0.18
thyX 3067727 c.219A>C synonymous_variant 0.18
thyX 3067739 c.207T>C synonymous_variant 0.19
thyX 3067742 c.204A>C synonymous_variant 0.19
thyX 3067761 p.Arg62Lys missense_variant 0.17
thyX 3067765 p.Leu61Ile missense_variant 0.17
thyX 3067781 c.165C>G synonymous_variant 0.18
thyX 3067787 c.159G>A synonymous_variant 0.16
thyX 3067793 c.153T>C synonymous_variant 0.15
thyX 3067799 c.147G>A synonymous_variant 0.15
thyX 3067802 c.144C>G synonymous_variant 0.15
thyA 3073764 c.708T>C synonymous_variant 1.0
thyA 3073862 p.Gly204Ser missense_variant 0.87
thyA 3073892 c.580T>C synonymous_variant 0.17
thyA 3073893 c.579C>G synonymous_variant 0.18
thyA 3073925 c.547T>C synonymous_variant 0.19
thyA 3073926 c.546G>C synonymous_variant 0.19
thyA 3073929 c.543T>C synonymous_variant 0.19
thyA 3073953 c.519T>C synonymous_variant 0.22
thyA 3073963 p.Leu170Gln missense_variant 0.77
thyA 3073977 c.495A>G synonymous_variant 0.25
thyA 3073989 c.483T>C synonymous_variant 0.22
thyA 3074001 c.471C>G synonymous_variant 0.2
thyA 3074004 c.468T>C synonymous_variant 0.2
thyA 3074010 c.462C>G synonymous_variant 0.19
thyA 3074031 c.441T>C synonymous_variant 0.17
thyA 3074076 c.396C>G synonymous_variant 0.14
thyA 3074117 c.355C>T synonymous_variant 0.15
fbiD 3339357 c.240G>T synonymous_variant 1.0
Rv3083 3448352 c.-152G>C upstream_gene_variant 1.0
Rv3083 3449624 p.Lys374Met missense_variant 1.0
Rv3083 3449919 c.1416C>A synonymous_variant 1.0
fbiB 3642227 p.Gln231His missense_variant 1.0
fbiB 3642581 c.1047A>C synonymous_variant 1.0
rpoA 3877542 c.966C>T synonymous_variant 0.16
rpoA 3877553 p.Glu319Gln missense_variant 0.16
rpoA 3877557 c.951C>G synonymous_variant 0.16
rpoA 3877587 c.921A>G synonymous_variant 0.18
rpoA 3877613 p.Ile299Val missense_variant 0.2
rpoA 3877638 c.870T>C synonymous_variant 0.16
rpoA 3877656 c.852T>C synonymous_variant 0.22
rpoA 3877668 c.840A>G synonymous_variant 0.21
rpoA 3877677 p.Ala277Ser missense_variant 0.18
rpoA 3877680 c.828G>C synonymous_variant 0.17
rpoA 3877686 c.822A>G synonymous_variant 0.17
rpoA 3877692 c.816G>C synonymous_variant 0.18
rpoA 3877704 c.804G>T synonymous_variant 0.18
rpoA 3877743 c.765T>C synonymous_variant 0.19
rpoA 3877764 c.744C>G synonymous_variant 0.15
rpoA 3877770 c.738A>G synonymous_variant 0.15
rpoA 3877776 c.732T>C synonymous_variant 0.16
rpoA 3877782 c.726T>C synonymous_variant 0.17
rpoA 3877839 c.669G>C synonymous_variant 0.16
rpoA 3877857 c.651G>A synonymous_variant 0.18
rpoA 3877866 c.642G>C synonymous_variant 0.17
rpoA 3877872 c.636C>T synonymous_variant 0.18
rpoA 3877875 c.633T>G synonymous_variant 0.18
rpoA 3877899 p.Ser203Thr missense_variant 0.16
rpoA 3877905 c.603A>G synonymous_variant 0.16
rpoA 3877908 p.Asn200Ser missense_variant 0.16
rpoA 3877953 c.555G>A synonymous_variant 0.18
rpoA 3877962 c.546G>T synonymous_variant 0.17
rpoA 3878025 c.483C>T synonymous_variant 0.15
rpoA 3878028 c.480G>C synonymous_variant 0.16
rpoA 3878040 c.468T>C synonymous_variant 0.17
rpoA 3878049 c.459G>C synonymous_variant 0.16
rpoA 3878055 c.453A>G synonymous_variant 0.16
rpoA 3878061 c.447G>C synonymous_variant 0.18
rpoA 3878067 c.441C>G synonymous_variant 0.18
rpoA 3878070 c.438T>C synonymous_variant 0.18
rpoA 3878082 c.426T>C synonymous_variant 0.15
rpoA 3878094 c.414C>G synonymous_variant 0.15
rpoA 3878118 c.390T>C synonymous_variant 0.17
rpoA 3878143 p.Gly122Asp missense_variant 0.14
rpoA 3878169 c.339G>C synonymous_variant 0.15
rpoA 3878184 c.324C>T synonymous_variant 0.16
rpoA 3878187 c.321C>G synonymous_variant 0.16
rpoA 3878193 c.315T>C synonymous_variant 0.15
rpoA 3878199 c.309T>C synonymous_variant 0.17
rpoA 3878202 c.306G>C synonymous_variant 0.17
rpoA 3878217 c.291A>G synonymous_variant 0.15
rpoA 3878220 c.288C>T synonymous_variant 0.17
rpoA 3878271 c.237T>C synonymous_variant 0.16
rpoA 3878284 p.Glu75Ala missense_variant 0.18
rpoA 3878292 c.216T>C synonymous_variant 0.18
rpoA 3878304 c.204G>C synonymous_variant 0.17
rpoA 3878313 c.195G>C synonymous_variant 0.15
rpoA 3878346 c.162T>C synonymous_variant 0.17
clpC1 4038278 c.2427T>C synonymous_variant 0.15
clpC1 4038293 c.2412G>C synonymous_variant 0.16
clpC1 4038302 c.2403C>G synonymous_variant 0.16
clpC1 4038308 p.Val799Ile missense_variant 0.16
clpC1 4038317 c.2388G>C synonymous_variant 0.16
clpC1 4038347 c.2358G>C synonymous_variant 0.18
clpC1 4038359 c.2346A>G synonymous_variant 0.16
clpC1 4038368 c.2337T>C synonymous_variant 0.19
clpC1 4038398 c.2307G>T synonymous_variant 0.16
clpC1 4038403 c.2302T>C synonymous_variant 0.18
clpC1 4038419 c.2286T>C synonymous_variant 0.17
clpC1 4038434 c.2271G>C synonymous_variant 0.15
clpC1 4038445 p.Ala754Thr missense_variant 0.14
clpC1 4038452 c.2253G>C synonymous_variant 0.18
clpC1 4038461 p.Ala748Asp missense_variant 0.17
clpC1 4038498 p.Ser736Thr missense_variant 0.17
clpC1 4038530 p.Glu725Asp missense_variant 0.15
clpC1 4038536 c.2169C>T synonymous_variant 0.15
clpC1 4038596 c.2109A>G synonymous_variant 0.15
clpC1 4038611 c.2094C>T synonymous_variant 0.17
clpC1 4038623 c.2082A>G synonymous_variant 0.17
clpC1 4038640 p.Asp689Asn missense_variant 0.15
clpC1 4038653 c.2052C>T synonymous_variant 0.19
clpC1 4038658 p.Lys683Gln missense_variant 0.17
clpC1 4038661 p.Ser682Thr missense_variant 0.17
clpC1 4038662 c.2043T>C synonymous_variant 0.17
clpC1 4038671 c.2034T>C synonymous_variant 0.2
clpC1 4038683 c.2022T>C synonymous_variant 0.2
clpC1 4038695 c.2010C>G synonymous_variant 0.21
clpC1 4038701 c.2004G>C synonymous_variant 0.18
clpC1 4038704 c.2001T>C synonymous_variant 0.19
clpC1 4038707 c.1998C>G synonymous_variant 0.19
clpC1 4038710 c.1995G>C synonymous_variant 0.19
clpC1 4038740 c.1965G>C synonymous_variant 0.19
clpC1 4038748 p.Arg653Cys missense_variant 0.16
clpC1 4038755 c.1950G>C synonymous_variant 0.17
clpC1 4038773 c.1932T>C synonymous_variant 0.18
clpC1 4038782 c.1923G>C synonymous_variant 0.18
clpC1 4038790 c.1915C>T synonymous_variant 0.17
clpC1 4038812 c.1893T>C synonymous_variant 0.18
clpC1 4038815 c.1890G>T synonymous_variant 0.19
clpC1 4038851 c.1854G>A synonymous_variant 0.16
clpC1 4038878 c.1827A>G synonymous_variant 0.19
clpC1 4038908 c.1797C>G synonymous_variant 0.17
clpC1 4038914 c.1791G>C synonymous_variant 0.18
clpC1 4038923 c.1782A>G synonymous_variant 0.19
clpC1 4038932 c.1773G>C synonymous_variant 0.19
clpC1 4038953 c.1752A>G synonymous_variant 0.15
clpC1 4038956 c.1749T>C synonymous_variant 0.16
clpC1 4038965 c.1740T>C synonymous_variant 0.17
clpC1 4038971 c.1734T>C synonymous_variant 0.16
clpC1 4038974 c.1731T>C synonymous_variant 0.16
clpC1 4038989 c.1716T>C synonymous_variant 0.17
clpC1 4038997 c.1708T>C synonymous_variant 0.15
clpC1 4039022 c.1683A>G synonymous_variant 0.2
clpC1 4039073 c.1632C>G synonymous_variant 0.17
clpC1 4039085 c.1620A>G synonymous_variant 0.2
clpC1 4039090 c.1615C>T synonymous_variant 0.2
clpC1 4039097 c.1608G>C synonymous_variant 0.21
clpC1 4039103 c.1602T>C synonymous_variant 0.18
clpC1 4039106 c.1599G>C synonymous_variant 0.17
clpC1 4039112 c.1593C>G synonymous_variant 0.16
clpC1 4039142 c.1563A>G synonymous_variant 0.16
clpC1 4039145 c.1560G>C synonymous_variant 0.16
clpC1 4039169 p.Glu512Asp missense_variant 0.14
clpC1 4039274 c.1431G>C synonymous_variant 0.16
clpC1 4039286 c.1419T>C synonymous_variant 0.14
clpC1 4039289 c.1416T>C synonymous_variant 0.15
clpC1 4039454 c.1251A>G synonymous_variant 0.15
clpC1 4039463 c.1242C>G synonymous_variant 0.16
clpC1 4039466 c.1239T>C synonymous_variant 0.17
clpC1 4039469 c.1236T>C synonymous_variant 0.16
clpC1 4039481 c.1224T>G synonymous_variant 0.16
clpC1 4039484 c.1221T>G synonymous_variant 0.14
clpC1 4039517 c.1188C>G synonymous_variant 0.18
clpC1 4039524 p.Phe394Tyr missense_variant 0.18
clpC1 4039526 c.1179G>C synonymous_variant 0.17
clpC1 4039547 c.1158C>G synonymous_variant 0.2
clpC1 4039553 c.1152C>G synonymous_variant 0.21
clpC1 4039562 c.1143C>G synonymous_variant 0.22
clpC1 4039565 c.1140G>C synonymous_variant 0.24
clpC1 4039576 p.Ala377Ser missense_variant 0.21
clpC1 4039577 c.1128T>C synonymous_variant 0.19
clpC1 4039586 c.1119G>C synonymous_variant 0.2
clpC1 4039610 c.1095G>C synonymous_variant 0.18
clpC1 4039616 c.1089G>C synonymous_variant 0.16
clpC1 4039622 c.1083C>G synonymous_variant 0.16
clpC1 4039904 c.801A>G synonymous_variant 0.15
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.19
clpC1 4039931 c.774T>C synonymous_variant 0.19
clpC1 4039946 c.759A>T synonymous_variant 0.23
clpC1 4039952 c.753T>C synonymous_variant 0.21
clpC1 4039958 c.747G>C synonymous_variant 0.22
clpC1 4039979 c.726C>G synonymous_variant 0.17
clpC1 4039996 p.Glu237Gln missense_variant 0.17
clpC1 4040021 c.684A>C synonymous_variant 0.2
clpC1 4040024 c.681A>G synonymous_variant 0.21
clpC1 4040033 c.672G>C synonymous_variant 0.2
clpC1 4040036 c.669C>G synonymous_variant 0.19
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.2
clpC1 4040093 c.612C>G synonymous_variant 0.2
clpC1 4040105 c.600C>G synonymous_variant 0.2
clpC1 4040147 c.558A>G synonymous_variant 0.19
clpC1 4040153 c.552A>G synonymous_variant 0.18
clpC1 4040162 c.543G>C synonymous_variant 0.16
clpC1 4040171 c.534C>G synonymous_variant 0.15
clpC1 4040201 c.504C>G synonymous_variant 0.17
clpC1 4040207 c.498T>C synonymous_variant 0.14
clpC1 4040354 c.351A>G synonymous_variant 0.15
clpC1 4040363 c.342A>C synonymous_variant 0.17
clpC1 4040369 c.336C>G synonymous_variant 0.16
clpC1 4040380 c.325T>C synonymous_variant 0.15
clpC1 4040381 c.324T>C synonymous_variant 0.15
clpC1 4040387 c.318A>G synonymous_variant 0.16
clpC1 4040393 c.312G>C synonymous_variant 0.15
clpC1 4040411 c.294T>C synonymous_variant 0.15
clpC1 4040423 c.282A>G synonymous_variant 0.16
clpC1 4040426 c.279T>C synonymous_variant 0.18
clpC1 4040431 c.274T>C synonymous_variant 0.18
clpC1 4040441 c.264C>G synonymous_variant 0.17
clpC1 4040444 c.261C>G synonymous_variant 0.15
clpC1 4040450 c.255A>G synonymous_variant 0.16
embC 4240578 p.Ala239Val missense_variant 0.16
embC 4240582 c.720C>G synonymous_variant 0.15
embC 4240585 c.723C>G synonymous_variant 0.15
embC 4240591 c.729C>G synonymous_variant 0.17
embC 4240594 c.732C>G synonymous_variant 0.18
embC 4240600 c.738G>C synonymous_variant 0.17
embC 4240632 p.Met257Thr missense_variant 0.19
embC 4240642 c.780G>C synonymous_variant 0.17
embC 4240654 c.792C>T synonymous_variant 0.17
embC 4240657 c.795G>C synonymous_variant 0.17
embC 4240671 p.Thr270Ile missense_variant 0.18
embC 4240678 c.816T>G synonymous_variant 0.18
embC 4240685 p.Thr275Ala missense_variant 0.16
embC 4240693 c.831T>C synonymous_variant 0.17
embC 4240706 p.Val282Thr missense_variant 0.16
embC 4240726 c.864G>C synonymous_variant 0.2
embC 4240780 c.918T>C synonymous_variant 0.15
embC 4240783 c.921G>C synonymous_variant 0.15
embC 4240789 c.927T>C synonymous_variant 0.17
embC 4240819 c.957A>G synonymous_variant 0.15
embC 4240825 c.963G>A synonymous_variant 0.14
embC 4240831 c.969T>G synonymous_variant 0.15
embC 4240867 c.1005T>G synonymous_variant 0.14
embC 4240870 c.1008T>C synonymous_variant 0.14
embC 4240880 p.Ala340Thr missense_variant 0.13
embC 4240885 c.1023T>C synonymous_variant 0.14
embC 4240897 c.1035C>G synonymous_variant 0.17
embC 4241104 c.1242G>A synonymous_variant 0.15
embC 4241107 c.1245G>C synonymous_variant 0.15
embC 4241141 p.Ile427Val missense_variant 0.15
embA 4244641 p.Val470Gly missense_variant 0.98
embA 4245197 c.1965C>T synonymous_variant 0.97
embB 4246641 p.Ala43Glu missense_variant 1.0
embB 4247233 p.Asp240Glu missense_variant 1.0
embB 4248118 c.1605T>C synonymous_variant 0.17
embB 4248127 c.1614G>C synonymous_variant 0.2
embB 4248133 c.1620C>G synonymous_variant 0.2
embB 4248142 c.1629T>C synonymous_variant 0.2
embB 4248143 c.1630T>C synonymous_variant 0.2
embB 4248157 c.1644A>G synonymous_variant 0.2
embB 4248206 p.Ser565Gly missense_variant 0.18
embB 4248220 c.1707A>G synonymous_variant 0.16
embB 4248241 c.1728C>T synonymous_variant 0.17
ethA 4327035 p.Tyr147Asp missense_variant 1.0
ethR 4327923 p.Gln125His missense_variant 1.0