TB-Profiler result

Run: ERR4816967
Summary

Run ID: ERR4816967

Sample name:

Date: 01-04-2023 14:43:58

Number of reads: 2014988

Percentage reads mapped: 67.18

Strain: lineage5

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage5 West-Africa 1 AFRI_2;AFRI_3 RD711 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.19 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.25 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.32 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.24 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.17 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9566 c.2265C>T synonymous_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 761051 c.1245G>C synonymous_variant 0.11
rpoB 761054 c.1248G>C synonymous_variant 0.11
rpoB 761057 c.1251G>C synonymous_variant 0.11
rpoB 761060 c.1254C>G synonymous_variant 0.14
rpoB 761084 c.1278C>A synonymous_variant 0.18
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.19
rpoB 761096 c.1290G>C synonymous_variant 0.21
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.21
rpoB 761102 c.1296A>G synonymous_variant 0.21
rpoB 761132 c.1326G>C synonymous_variant 0.18
rpoB 761133 c.1327T>C synonymous_variant 0.18
rpoB 761150 c.1344A>C synonymous_variant 0.21
rpoB 761594 c.1788C>T synonymous_variant 0.14
rpoB 761600 c.1794T>A synonymous_variant 0.13
rpoB 762233 c.2427G>C synonymous_variant 0.15
rpoB 762239 c.2433G>A synonymous_variant 0.13
rpoB 762245 c.2439G>C synonymous_variant 0.16
rpoB 762254 c.2448T>C synonymous_variant 0.12
rpoB 762266 c.2460T>C synonymous_variant 0.13
rpoB 762870 p.Met1022Gln missense_variant 0.12
rpoB 762879 p.Met1025Leu missense_variant 0.23
rpoC 762902 c.-468C>T upstream_gene_variant 0.33
rpoC 762911 c.-459C>T upstream_gene_variant 0.34
rpoC 762917 c.-453C>T upstream_gene_variant 0.31
rpoC 762920 c.-450C>T upstream_gene_variant 0.31
rpoC 762929 c.-441G>T upstream_gene_variant 0.35
rpoC 762944 c.-426C>T upstream_gene_variant 0.29
rpoC 762956 c.-414G>C upstream_gene_variant 0.22
rpoC 762989 c.-381G>C upstream_gene_variant 0.16
rpoC 762995 c.-375G>T upstream_gene_variant 0.11
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763070 c.-300T>C upstream_gene_variant 0.12
rpoB 763077 p.Val1091Ile missense_variant 0.12
rpoC 763103 c.-267G>C upstream_gene_variant 0.13
rpoC 763511 p.Cys48Gly missense_variant 0.15
rpoC 763517 p.Lys50Gln missense_variant 0.16
rpoC 763528 c.159G>C synonymous_variant 0.17
rpoC 763531 c.162G>C synonymous_variant 0.17
rpoC 763534 c.165T>C synonymous_variant 0.16
rpoC 763546 c.177A>G synonymous_variant 0.13
rpoC 763550 p.Tyr61Ala missense_variant 0.12
rpoC 763570 c.201G>C synonymous_variant 0.13
rpoC 763657 p.Glu96Asp missense_variant 0.13
rpoC 763660 c.291T>G synonymous_variant 0.13
rpoC 763666 c.297G>C synonymous_variant 0.2
rpoC 763675 c.306C>G synonymous_variant 0.28
rpoC 763699 c.330G>T synonymous_variant 0.27
rpoC 763708 c.339G>C synonymous_variant 0.25
rpoC 763714 c.345G>C synonymous_variant 0.21
rpoC 763717 c.348T>C synonymous_variant 0.18
rpoC 763718 p.Leu117Val missense_variant 0.17
rpoC 763723 c.354G>C synonymous_variant 0.18
rpoC 763724 p.Asp119Asn missense_variant 0.18
rpoC 763729 c.360G>C synonymous_variant 0.18
rpoC 763732 c.363C>G synonymous_variant 0.18
rpoC 763735 c.366G>C synonymous_variant 0.19
rpoC 763744 c.375G>C synonymous_variant 0.19
rpoC 763751 p.Ile128Val missense_variant 0.17
rpoC 764512 c.1143G>C synonymous_variant 0.12
rpoC 764521 c.1152T>C synonymous_variant 0.17
rpoC 764536 c.1167G>C synonymous_variant 0.17
rpoC 764543 p.Thr392Ala missense_variant 0.16
rpoC 764548 c.1179G>T synonymous_variant 0.14
rpoC 764551 c.1182G>C synonymous_variant 0.18
rpoC 764566 c.1197C>G synonymous_variant 0.17
rpoC 764573 p.Leu402Ile missense_variant 0.19
rpoC 764578 c.1209C>G synonymous_variant 0.19
rpoC 764581 c.1212T>C synonymous_variant 0.19
rpoC 764582 p.Leu405Met missense_variant 0.19
rpoC 764602 c.1233C>T synonymous_variant 0.22
rpoC 764605 c.1236G>T synonymous_variant 0.21
rpoC 764611 c.1242G>T synonymous_variant 0.23
rpoC 764632 c.1263T>A synonymous_variant 0.22
rpoC 764647 c.1278C>T synonymous_variant 0.32
rpoC 764650 c.1281G>T synonymous_variant 0.34
rpoC 764653 c.1284G>C synonymous_variant 0.28
rpoC 764656 c.1287C>T synonymous_variant 0.31
rpoC 764662 c.1293G>C synonymous_variant 0.31
rpoC 764677 c.1308C>A synonymous_variant 0.22
rpoC 764678 p.Lys437Gln missense_variant 0.28
rpoC 764683 c.1314G>C synonymous_variant 0.22
rpoC 764692 c.1323C>T synonymous_variant 0.37
rpoC 764705 p.Leu446Glu missense_variant 0.13
rpoC 764713 c.1344G>C synonymous_variant 0.17
rpoC 764731 c.1362G>C synonymous_variant 0.16
rpoC 764737 c.1368G>T synonymous_variant 0.16
rpoC 764746 c.1377G>T synonymous_variant 0.17
rpoC 764755 p.Asp462Glu missense_variant 0.17
rpoC 764758 c.1389C>G synonymous_variant 0.17
rpoC 764760 p.Asn464Ser missense_variant 0.17
rpoC 764764 c.1395T>C synonymous_variant 0.17
rpoC 764767 c.1398G>T synonymous_variant 0.16
rpoC 764776 c.1407C>T synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781751 c.192G>C synonymous_variant 0.16
rpsL 781754 c.195G>A synonymous_variant 0.14
rpsL 781760 c.201T>C synonymous_variant 0.3
rpsL 781766 c.207C>T synonymous_variant 0.31
rpsL 781772 c.213C>T synonymous_variant 0.22
rpsL 781796 p.Met79Ile missense_variant 0.23
rpsL 781802 c.243G>C synonymous_variant 0.32
rpsL 781805 c.246G>T synonymous_variant 0.25
rpsL 781811 c.252C>T synonymous_variant 0.37
rpsL 781814 c.255C>T synonymous_variant 0.36
rpsL 781817 c.258G>T synonymous_variant 0.35
rpsL 781829 c.270G>C synonymous_variant 0.19
rpsL 781832 c.273T>C synonymous_variant 0.26
rpsL 781838 c.279G>T synonymous_variant 0.16
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 0.2
rrs 1471997 n.152T>C non_coding_transcript_exon_variant 0.25
rrs 1472023 n.178G>C non_coding_transcript_exon_variant 0.22
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.58
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.71
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.78
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.15
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.24
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.76
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.2
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.2
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.63
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.65
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.63
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.97
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.57
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.49
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.48
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.37
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.29
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.29
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.8
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.67
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.78
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.67
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.62
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.62
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.62
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.62
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.33
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 1.0
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 1.0
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 1.0
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 1.0
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.4
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.25
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.75
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.82
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.4
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.21
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.36
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.35
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.42
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.39
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.42
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.42
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.34
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.25
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.41
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.26
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.47
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.29
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.23
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.37
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.16
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.41
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.41
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.17
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.32
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.48
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 1.0
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.13
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.85
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.67
rrs 1472675 n.830T>A non_coding_transcript_exon_variant 1.0
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 1.0
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.44
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.1
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.25
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.3
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.67
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.31
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.31
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.33
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.27
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.3
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.65
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.32
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.34
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.86
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.61
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.17
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.83
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 0.62
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 0.4
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.99
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.44
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.14
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.33
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.43
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.85
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.91
rrs 1472958 n.1113A>C non_coding_transcript_exon_variant 0.14
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.13
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.51
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.57
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.19
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.44
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.12
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.39
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.89
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.33
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.35
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.99
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.99
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.98
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.98
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.41
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.4
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.98
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.97
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.95
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.94
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.96
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.99
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.99
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.54
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.91
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.44
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.46
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.96
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.96
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.52
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.54
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.53
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.94
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.94
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.23
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.91
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.78
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.66
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.58
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.61
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.72
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.86
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.26
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.89
rrl 1473384 n.-274A>G upstream_gene_variant 0.15
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.8
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.88
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.94
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.95
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.89
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474326 n.669T>A non_coding_transcript_exon_variant 0.5
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.75
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.75
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.5
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 1.0
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474406 n.749T>A non_coding_transcript_exon_variant 0.67
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.67
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.6
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.33
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.86
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.71
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.8
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.89
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.89
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.17
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.83
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.83
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.83
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.83
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.17
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.18
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.14
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 1.0
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.14
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.86
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.83
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.91
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.9
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.9
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.91
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.88
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.88
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.91
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.11
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.95
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.95
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.89
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.8
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.57
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.5
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.5
rrl 1475109 n.1452C>T non_coding_transcript_exon_variant 0.38
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.5
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.6
rrl 1475137 n.1480A>T non_coding_transcript_exon_variant 0.62
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.45
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.45
rrl 1475188 n.1531C>G non_coding_transcript_exon_variant 0.22
rrl 1475194 n.1537C>G non_coding_transcript_exon_variant 0.25
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 1.0
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 1.0
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 0.8
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 0.8
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 0.8
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 0.8
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.8
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.8
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.8
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.5
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.67
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.67
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 1.0
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 1.0
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.86
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.77
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.75
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.75
rrl 1475767 n.2110_2111insT non_coding_transcript_exon_variant 0.73
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.79
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.47
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.31
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.38
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.62
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.62
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.31
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.31
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.62
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.88
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.83
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.56
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.62
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.62
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.62
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.83
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.8
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.8
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.75
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 1.0
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.5
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.62
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.14
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.9
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.52
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.67
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.41
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.76
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.58
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.76
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.82
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.12
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.9
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.23
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.28
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.12
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.14
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.82
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.78
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.14
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.95
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.58
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.53
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.46
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.23
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.69
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.75
rrl 1476295 n.2638C>A non_coding_transcript_exon_variant 0.75
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.75
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.75
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 0.75
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.75
rrl 1476311 n.2654G>T non_coding_transcript_exon_variant 0.6
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.75
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.28
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.13
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.94
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.95
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.83
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.68
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.7
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.86
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.63
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.71
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.35
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.63
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.32
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.54
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.17
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.59
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.57
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.32
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.18
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.52
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.52
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.35
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.33
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.35
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.35
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.35
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.25
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.4
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.55
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.55
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.55
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.21
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.15
inhA 1673338 c.-864G>A upstream_gene_variant 1.0
rpsA 1833721 c.180A>G synonymous_variant 0.12
rpsA 1833724 c.183C>T synonymous_variant 0.12
rpsA 1833727 c.186G>C synonymous_variant 0.17
rpsA 1833732 p.Pro64Leu missense_variant 0.12
rpsA 1833734 p.Ala65Ser missense_variant 0.16
rpsA 1833742 c.201A>G synonymous_variant 0.17
rpsA 1833764 p.Asp75Asn missense_variant 0.12
rpsA 1834189 c.648G>C synonymous_variant 0.17
rpsA 1834195 c.654G>C synonymous_variant 0.27
rpsA 1834234 c.693G>C synonymous_variant 0.5
rpsA 1834240 c.699T>C synonymous_variant 0.48
rpsA 1834246 c.705G>T synonymous_variant 0.51
rpsA 1834249 c.708T>C synonymous_variant 0.56
rpsA 1834258 c.717G>A synonymous_variant 0.41
rpsA 1834261 c.720A>G synonymous_variant 0.53
rpsA 1834264 c.723G>C synonymous_variant 0.5
rpsA 1834294 c.753G>C synonymous_variant 0.41
rpsA 1834298 p.Gln253Glu missense_variant 0.4
rpsA 1834306 c.765T>C synonymous_variant 0.33
rpsA 1834307 p.Asp256Gln missense_variant 0.33
rpsA 1834312 c.771G>A synonymous_variant 0.33
rpsA 1834327 c.786G>T synonymous_variant 0.25
rpsA 1834345 c.804C>T synonymous_variant 0.12
rpsA 1834417 c.876G>C synonymous_variant 0.12
rpsA 1834423 c.882G>C synonymous_variant 0.12
rpsA 1834427 p.Ile296Val missense_variant 0.12
rpsA 1834435 c.894G>C synonymous_variant 0.15
rpsA 1834451 c.910T>C synonymous_variant 0.22
rpsA 1834459 c.918G>C synonymous_variant 0.19
rpsA 1834465 c.924T>C synonymous_variant 0.17
rpsA 1834468 c.927A>G synonymous_variant 0.18
rpsA 1834474 c.933C>G synonymous_variant 0.18
rpsA 1834486 p.Glu315Asp missense_variant 0.19
rpsA 1834489 c.948T>C synonymous_variant 0.2
rpsA 1834501 c.960G>C synonymous_variant 0.16
rpsA 1834504 c.963G>C synonymous_variant 0.16
rpsA 1834522 c.981C>T synonymous_variant 0.12
rpsA 1834523 p.Glu328Gln missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101921 c.1122G>A synonymous_variant 1.0
ndh 2103112 c.-70G>T upstream_gene_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2156570 c.-459C>A upstream_gene_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168148 p.Pro822Gln missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290062 c.-821G>A upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
ald 3087184 c.368_373delCCGACG disruptive_inframe_deletion 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474026 p.Ala7Val missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
alr 3840932 c.489C>T synonymous_variant 1.0
ddn 3986987 c.144G>T synonymous_variant 1.0
ddn 3987180 p.Asp113Asn missense_variant 1.0
clpC1 4039994 p.Glu237Asp missense_variant 0.12
clpC1 4040009 c.696C>G synonymous_variant 0.15
clpC1 4040015 c.690G>C synonymous_variant 0.16
clpC1 4040018 c.687G>C synonymous_variant 0.15
clpC1 4040021 c.684A>C synonymous_variant 0.15
clpC1 4040024 c.681A>G synonymous_variant 0.16
clpC1 4040036 c.669C>G synonymous_variant 0.15
clpC1 4040042 c.663C>T synonymous_variant 0.14
clpC1 4040066 c.639G>C synonymous_variant 0.12
clpC1 4040824 c.-120C>T upstream_gene_variant 1.0
embC 4239843 c.-20A>C upstream_gene_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embA 4244635 p.Val468Ala missense_variant 1.0
embA 4245147 p.Pro639Ser missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4327103 p.Gly124Asp missense_variant 1.0
ethA 4327355 p.Ser40Phe missense_variant 1.0
whiB6 4338541 c.-21delA upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408144 p.Arg20Pro missense_variant 1.0