Run ID: ERR13285192
Sample name:
Date: 2024-10-04T04:57:20.009235
Number of reads: 57475
Percentage reads mapped: 58.11
Median coverage: 0.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4 | Euro-American | None | 1.0 |
lineage4.9 | Euro-American (H37Rv-like) | None | 0.99 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7448 | c.147G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7487 | c.186C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7496 | c.195C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7499 | c.198G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7506 | p.Ser69Gly | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 7517 | c.216G>A | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7652 | c.351C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7661 | c.360C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7671 | p.Pro124Ala | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7679 | c.378G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7700 | c.399G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7706 | c.405C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7748 | c.447A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7781 | c.480G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7790 | c.489G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7797 | c.496_498delCTAinsTTG | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7821 | c.520C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7832 | c.531G>C | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>C | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7847 | c.546G>C | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7853 | c.552C>T | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7859 | c.558A>C | synonymous_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.87 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7871 | c.570G>C | synonymous_variant | 0.87 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7883 | c.582G>C | synonymous_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7884 | p.Arg195Asn | missense_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7889 | c.588G>A | synonymous_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7892 | c.591G>C | synonymous_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7898 | p.Asp199Glu | missense_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7906 | p.Phe202Tyr | missense_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7919 | p.Glu206Asp | missense_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7922 | c.621T>C | synonymous_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9056 | c.1755C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9074 | c.1773G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761150 | c.1344A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761171 | c.1365C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761183 | c.1377T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761189 | c.1383T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761220 | c.1414_1416delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762110 | c.2304G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762134 | c.2328C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762170 | c.2364C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762236 | c.2430G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762296 | c.2490G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762398 | c.-972T>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762407 | c.-963G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762410 | c.2604T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762486 | p.Pro894Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 762489 | p.Val895Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 763781 | p.Ser138Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 1.0 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763819 | c.450G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763825 | c.456G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763831 | c.462A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763836 | p.Ala156Gly | missense_variant | 1.0 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763867 | c.498C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764075 | p.Val236Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764085 | p.Asn239Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 764087 | p.Leu240Ile | missense_variant | 1.0 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764113 | c.744C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764134 | c.765C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764191 | c.822C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764213 | p.Arg282Lys | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 764227 | c.858G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765493 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765520 | c.2151G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765529 | c.2160C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765550 | c.2181C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765565 | c.2196G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765611 | p.His748Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765658 | c.2289C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765661 | c.2292T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765662 | c.2293_2295delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765669 | p.His767Arg | missense_variant | 1.0 | rifampicin | |
rpoC | 765681 | p.Asn771Thr | missense_variant | 1.0 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765712 | c.2343C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765718 | p.Asp783Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765728 | p.Gln787Asn | missense_variant | 1.0 | rifampicin | |
rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765752 | p.Asp795Ser | missense_variant | 1.0 | rifampicin | |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 765778 | c.2409C>G | synonymous_variant | 0.93 | rifampicin | |
rpoC | 765781 | p.Asp804Glu | missense_variant | 0.96 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765817 | c.2448G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765826 | c.2457T>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 765875 | p.Val836Ile | missense_variant | 0.96 | rifampicin | Uncertain significance |
rpoC | 765884 | c.2515_2516delTCinsAG | synonymous_variant | 0.95 | rifampicin | |
rpoC | 765952 | c.2583G>C | synonymous_variant | 0.92 | rifampicin | |
rpoC | 765962 | c.2593T>C | synonymous_variant | 0.93 | rifampicin | |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 766003 | c.2634G>C | synonymous_variant | 0.93 | rifampicin | |
rpoC | 766012 | c.2643C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766387 | c.3018C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766459 | c.3090G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766517 | p.Thr1050Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.9 | rifampicin | |
rpoC | 766525 | c.3156G>C | synonymous_variant | 0.9 | rifampicin | |
rpoC | 766526 | p.Val1053Ile | missense_variant | 0.9 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766534 | c.3165C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 766542 | p.Gly1058Asp | missense_variant | 1.0 | rifampicin | |
rpoC | 766564 | c.3195C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766568 | p.Val1067Ile | missense_variant | 1.0 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766592 | p.Val1075Leu | missense_variant | 1.0 | rifampicin | |
rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
rrl | 1475202 | n.1545G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475217 | n.1560T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475243 | n.1586G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475375 | n.1718G>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475378 | n.1723_1724delCG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475383 | n.1726_1727insCC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475395 | n.1738T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475396 | n.1739C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475397 | n.1740G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475403 | n.1746T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475404 | n.1747A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475407 | n.1750C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1475409 | n.1752T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475460 | n.1803A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475477 | n.1820_1821insT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475586 | n.1929C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475606 | n.1949T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475612 | n.1955G>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475621 | n.1964T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475629 | n.1973dupA | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476025 | n.2368G>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476085 | n.2428G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476105 | n.2448G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476114 | n.2457T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476119 | n.2462G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476165 | n.2508T>A | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
inhA | 1674534 | c.333G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674550 | p.Ser117Ala | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674570 | c.369G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674573 | c.372G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674576 | c.375T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674601 | p.Leu134Val | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674630 | c.429C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674656 | p.Ser152Thr | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674687 | c.486G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674696 | c.495G>A | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674702 | c.501G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
rpsA | 1834144 | c.603G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834154 | p.Asn205His | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834231 | c.690T>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
tsnR | 1853420 | c.-186T>C | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 1.0 | linezolid | |
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 1.0 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>A | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783051 | p.Tyr331Phe | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783053 | c.990C>T | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783071 | c.972C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783083 | c.960G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783131 | c.912C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783335 | c.708C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783371 | c.672A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783422 | c.621T>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783425 | p.Pro206Glu | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783446 | c.597A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783464 | c.579A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783499 | c.544T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783506 | c.537C>T | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783509 | c.534C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783602 | c.441G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783611 | c.432C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783659 | c.384A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783737 | c.306C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783746 | c.297G>A | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783764 | p.Met93Leu | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783773 | c.270A>G | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783788 | c.255T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627215 | c.-602G>T | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627218 | c.-605G>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627227 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627239 | c.111C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627301 | c.-688T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627305 | c.-692T>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627323 | c.-712_-710delTTGinsCTC | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627326 | c.-713T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627336 | p.Arg5Lys | missense_variant | 1.0 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrA | 3627343 | p.Thr3Pro | missense_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627344 | p.Asp2Glu | missense_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627351 | c.-738C>A | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877587 | p.Ser307Ala | missense_variant | 1.0 | rifampicin | |
rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877677 | c.831G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877685 | c.823C>T | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877689 | c.819C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877707 | c.801G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877710 | c.798C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877731 | c.777G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877803 | c.705G>A | synonymous_variant | 1.0 | rifampicin | |
clpC1 | 4038698 | c.2007C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038721 | c.1984C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039124 | c.1581C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039127 | p.Lys526Asn | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039133 | c.1572C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039139 | p.Glu522Asp | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039199 | c.1506C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>G | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4039292 | c.1413C>G | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4039304 | c.1401G>A | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4039320 | p.Ala462Ser | missense_variant | 0.92 | pyrazinamide | |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.92 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.92 | pyrazinamide | |
clpC1 | 4039338 | p.Thr456Gln | missense_variant | 0.92 | pyrazinamide | |
clpC1 | 4039347 | p.Arg453Gln | missense_variant | 0.92 | pyrazinamide | Uncertain significance |
clpC1 | 4039352 | c.1353C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040450 | c.255A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040459 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040471 | c.234T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040480 | c.225T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040486 | c.219G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040531 | c.174T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040534 | c.171A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040540 | c.165G>C | synonymous_variant | 1.0 | pyrazinamide | |
embC | 4241107 | c.1245G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4241141 | p.Ile427Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241167 | c.1305C>G | synonymous_variant | 1.0 | ethambutol |