Run ID: 85c9af2d-d87a-406b-95e7-2f0a844a7720
Sample name:
Date: 02-04-2024 05:25:33
Number of reads: 16212
Percentage reads mapped: 3.82
Median coverage: 0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.27 |
| lineage6.3.1 | West-Africa 2 | RD702 | 1.0 |
| lineage4.6.4 | Euro-American | None | 0.06 |
| lineage3.1.2.2 | East-African-Indian | RD750 | 1.0 |
| lineage1.2.1.2.1 | Indo-Oceanic | RD239 | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | ||||
| amikacin | ||||
| kanamycin | ||||
| capreomycin | ||||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7592 | c.291G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7613 | c.312G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7661 | c.360C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7667 | c.366C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7670 | c.369A>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7671 | p.Pro124Ala | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7676 | c.375G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7679 | c.378G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7683 | c.382_384delAGGinsCGT | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7706 | c.405C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCGT | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7760 | c.459C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7763 | c.462T>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| rpoB | 760244 | c.438G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760316 | c.510C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760325 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760334 | c.528G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760357 | p.Thr184Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 760415 | c.609C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760457 | c.651C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760463 | c.657C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760511 | c.705G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760514 | c.708C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760561 | c.757_758delCG | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 760567 | p.Ser254Trp | missense_variant | 1.0 | rifampicin | |
| rpoB | 760568 | c.762_763insGC | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 760571 | c.765G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760585 | p.Asn260Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760595 | c.789C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760596 | p.Thr264Pro | missense_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760769 | c.963C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760784 | c.978G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760787 | c.981G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760859 | c.1053T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760877 | c.1071G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760889 | c.1083C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760910 | c.1104C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760916 | c.1110C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760919 | c.1113C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760965 | p.Met387Leu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760970 | c.1164G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760973 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760988 | c.1182C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760991 | c.1185G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760997 | c.1191G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761051 | c.1245G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761054 | c.1248G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761063 | c.1257C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761147 | c.1341C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761198 | c.1392G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761217 | p.Pro471Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761220 | c.1414_1416delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761234 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762038 | c.2232C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762047 | c.2241G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762137 | c.2331C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762245 | c.2439G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762989 | c.-381G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762995 | c.-375G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763004 | c.-366G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763007 | c.-363C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763028 | c.-342T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763031 | c.-339T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763053 | c.-317T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763070 | c.-300T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763085 | c.-285C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763621 | c.252C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763666 | c.297G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763699 | c.330G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763705 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763709 | c.340C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763727 | c.358C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763747 | c.378G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764605 | c.1236G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764701 | c.1332C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764713 | c.1344G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781724 | c.165G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781737 | p.Gln60Gly | missense_variant | 1.0 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781766 | c.207C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781772 | c.213C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781793 | c.234G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781814 | c.255C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781817 | c.258G>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781829 | c.270G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781841 | c.282C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781859 | c.300T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781901 | c.342C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rrs | 1472019 | n.174G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472286 | n.441C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472287 | n.442C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472289 | n.444T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472290 | n.445C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472297 | n.453_465delGTCCGGGTTCTCT | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472324 | n.479G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472325 | n.480G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472327 | n.482G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472328 | n.483G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472337 | n.492C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472380 | n.535G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472848 | n.1003T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472859 | n.1014G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473829 | n.172G>T | non_coding_transcript_exon_variant | 0.8 | linezolid | |
| rrl | 1473830 | n.173T>G | non_coding_transcript_exon_variant | 0.8 | linezolid | |
| rrl | 1473831 | n.174G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474640 | n.983C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474676 | n.1019T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474677 | n.1020A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474710 | n.1053T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474711 | n.1054G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474712 | n.1055G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474713 | n.1056T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475603 | n.1946G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475612 | n.1955G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475615 | n.1958C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475616 | n.1959A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475618 | n.1961C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475629 | n.1972G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475637 | n.1980T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475638 | n.1981C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475643 | n.1986C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475647 | n.1990G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475753 | n.2096C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475762 | n.2105G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475764 | n.2107A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475765 | n.2108A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475775 | n.2118G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1475991 | n.2334T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476105 | n.2448G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476251 | n.2594T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476540 | n.2883C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476665 | n.3008T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833970 | c.429G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833991 | c.450C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpoA | 3877749 | c.759C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877856 | c.652T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878197 | p.Glu104Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038842 | c.1863G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038890 | c.1815G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide |
