TB-Profiler result

Run: SRR5007165
Summary

Run ID: SRR5007165

Sample name:

Date: 04-04-2023 07:51:21

Number of reads: 485289

Percentage reads mapped: 8.1

Strain: lineage3

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761109 p.Asp435Asn missense_variant 0.36 rifampicin
rpoB 761127 p.Ser441Ala missense_variant 0.38 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.89 streptomycin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.67
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759620 c.-187A>C upstream_gene_variant 0.33
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 761037 c.1231T>C synonymous_variant 0.57
rpoB 761051 c.1245G>C synonymous_variant 0.67
rpoB 761054 c.1248G>C synonymous_variant 0.67
rpoB 761057 c.1251G>C synonymous_variant 0.6
rpoB 761060 c.1254C>G synonymous_variant 0.6
rpoB 761084 c.1278C>A synonymous_variant 0.55
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.5
rpoB 761096 c.1290G>C synonymous_variant 0.5
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.45
rpoB 761102 c.1296A>G synonymous_variant 0.42
rpoB 761132 c.1326G>C synonymous_variant 0.38
rpoB 761133 c.1327T>C synonymous_variant 0.38
rpoB 761150 c.1344A>T synonymous_variant 0.33
rpoB 761159 c.1353G>C synonymous_variant 0.38
rpoB 761165 c.1359G>C synonymous_variant 0.36
rpoB 761180 c.1374A>C synonymous_variant 0.33
rpoB 761933 c.2127G>C synonymous_variant 0.22
rpoB 761948 c.2142G>C synonymous_variant 0.25
rpoB 761951 c.2145G>C synonymous_variant 0.25
rpoB 761955 p.Ile717Tyr missense_variant 0.25
rpoB 761961 p.Pro719Ser missense_variant 0.25
rpoB 761969 c.2163G>A synonymous_variant 0.33
rpoB 761974 p.His723Leu missense_variant 0.4
rpoB 761990 c.2184G>C synonymous_variant 0.4
rpoB 762000 c.2194_2195delTCinsAG synonymous_variant 0.4
rpoB 762003 p.Asn733Arg missense_variant 0.33
rpoB 762009 p.Leu735Val missense_variant 0.33
rpoB 762024 p.Val740Ile missense_variant 0.29
rpoB 762051 p.His749Tyr missense_variant 0.29
rpoB 762057 p.Ile751Val missense_variant 0.29
rpoB 762062 c.2256T>C synonymous_variant 0.33
rpoB 762065 c.2259T>C synonymous_variant 0.29
rpoB 762110 c.2304G>C synonymous_variant 0.38
rpoB 762114 p.Ile770Val missense_variant 0.38
rpoB 762126 p.Val774Met missense_variant 0.29
rpoB 762131 c.2325C>G synonymous_variant 0.25
rpoB 762137 c.2331C>T synonymous_variant 0.18
rpoB 762140 c.2334G>C synonymous_variant 0.18
rpoB 762143 c.2337T>C synonymous_variant 0.27
rpoB 762149 c.2343G>C synonymous_variant 0.27
rpoB 762158 c.2352G>C synonymous_variant 0.27
rpoB 762167 c.2361T>C synonymous_variant 0.3
rpoB 762175 c.2369_2370insC frameshift_variant 0.22
rpoB 762178 c.2373delC frameshift_variant 0.25
rpoB 762181 p.Asp792Ala missense_variant 0.33
rpoB 762185 c.2379G>C synonymous_variant 0.33
rpoB 762197 c.2391C>T synonymous_variant 0.29
rpoB 762218 c.2412T>C synonymous_variant 0.5
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 762831 c.-539_-538delAGinsTC upstream_gene_variant 0.2
rpoC 762845 c.-525C>T upstream_gene_variant 0.18
rpoB 762855 p.Val1017Ile missense_variant 0.33
rpoB 762858 p.Thr1018Ser missense_variant 0.33
rpoC 762863 c.-507T>G upstream_gene_variant 0.33
rpoB 762871 p.Met1022Thr missense_variant 0.38
rpoB 762878 p.Ile1024Met missense_variant 0.38
rpoB 762879 p.Met1025Leu missense_variant 0.38
rpoC 762887 c.-483G>C upstream_gene_variant 0.38
rpoC 762899 c.-471G>C upstream_gene_variant 0.38
rpoC 762926 c.-444C>G upstream_gene_variant 0.4
rpoC 762929 c.-441G>C upstream_gene_variant 0.45
rpoC 762947 c.-423C>G upstream_gene_variant 0.56
rpoC 762971 c.-399G>C upstream_gene_variant 0.69
rpoC 762980 c.-390T>C upstream_gene_variant 0.69
rpoC 762989 c.-381G>C upstream_gene_variant 0.73
rpoC 762995 c.-375G>C upstream_gene_variant 0.73
rpoB 763005 p.Cys1067Val missense_variant 0.73
rpoB 763014 p.Met1070Leu missense_variant 0.73
rpoB 763017 p.Gln1071Glu missense_variant 0.73
rpoC 763022 c.-348C>T upstream_gene_variant 0.77
rpoC 763028 c.-342T>C upstream_gene_variant 0.79
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.79
rpoC 763043 c.-327G>C upstream_gene_variant 0.92
rpoC 763053 c.-317T>C upstream_gene_variant 0.92
rpoC 763070 c.-300T>C upstream_gene_variant 0.92
rpoB 763077 p.Val1091Thr missense_variant 0.82
rpoC 763103 c.-267G>C upstream_gene_variant 0.8
rpoC 763115 c.-255T>C upstream_gene_variant 0.43
rpoB 763119 p.Asn1105Asp missense_variant 0.43
rpoC 763507 c.138G>C synonymous_variant 0.29
rpoC 763531 c.162G>C synonymous_variant 0.29
rpoC 763534 c.165T>C synonymous_variant 0.43
rpoC 763546 c.177A>G synonymous_variant 0.29
rpoC 763550 p.Tyr61Ala missense_variant 0.29
rpoC 763570 c.201G>C synonymous_variant 0.29
rpoC 763578 p.Phe70Tyr missense_variant 0.29
rpoC 763622 p.Ala85Ser missense_variant 0.33
rpoC 763660 c.291T>C synonymous_variant 0.4
rpoC 764347 c.978G>C synonymous_variant 0.5
rpoC 764353 c.984G>T synonymous_variant 0.5
rpoC 764359 c.990C>G synonymous_variant 0.4
rpoC 764371 c.1002G>C synonymous_variant 0.5
rpoC 764377 c.1008C>G synonymous_variant 0.5
rpoC 764380 c.1011G>C synonymous_variant 0.4
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.4
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.33
rpoC 764410 c.1041G>C synonymous_variant 0.33
rpoC 764424 p.Asn352Thr missense_variant 0.4
rpoC 764428 c.1059G>A synonymous_variant 0.4
rpoC 764431 c.1062G>C synonymous_variant 0.4
rpoC 764434 c.1065A>G synonymous_variant 0.4
rpoC 764435 c.1066A>C synonymous_variant 0.4
rpoC 764441 p.Ile358Leu missense_variant 0.4
rpoC 764446 p.Asp359Glu missense_variant 0.4
rpoC 764452 c.1083T>C synonymous_variant 0.4
rpoC 764455 c.1086G>C synonymous_variant 0.4
rpoC 764458 c.1089G>C synonymous_variant 0.33
rpoC 764461 c.1092A>G synonymous_variant 0.33
rpoC 764485 c.1116G>C synonymous_variant 0.33
rpoC 764491 c.1122G>T synonymous_variant 0.33
rpoC 764632 c.1263T>C synonymous_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775710 p.Phe924Ser missense_variant 0.15
mmpL5 775751 c.2729delT frameshift_variant 0.18
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781363 c.-197T>G upstream_gene_variant 0.25
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781802 c.243G>C synonymous_variant 0.17
rpsL 781814 c.255C>T synonymous_variant 0.22
rpsL 781817 c.258G>T synonymous_variant 0.22
fbiC 1304808 c.1878C>A synonymous_variant 0.29
Rv1258c 1407081 p.Ala87Gly missense_variant 0.5
atpE 1460986 c.-59A>G upstream_gene_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 0.9
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.17
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.2
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.56
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.56
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.71
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.65
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.68
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.7
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.19
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.88
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.3
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.48
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.54
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.4
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.62
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.77
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.45
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.4
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.56
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.46
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.73
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.21
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.2
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.29
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.71
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.5
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.62
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.71
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.6
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.33
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.33
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.33
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.33
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.33
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.29
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.29
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.43
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.33
rrs 1472498 n.653C>A non_coding_transcript_exon_variant 0.86
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.81
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.13
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.8
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.8
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.84
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.85
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.84
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.84
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.83
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.85
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.86
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.97
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.88
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.88
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.27
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.98
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.92
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.92
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.88
rrs 1472673 n.828T>A non_coding_transcript_exon_variant 0.92
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.8
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.95
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.92
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.98
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 0.9
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.97
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.96
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.93
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.91
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.91
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.88
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.88
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.77
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.45
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.42
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.24
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.18
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.57
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.47
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.24
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.68
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.59
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.17
rrs 1472969 n.1125_1126delCG non_coding_transcript_exon_variant 0.17
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.62
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.53
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.17
rrs 1472975 n.1130T>A non_coding_transcript_exon_variant 0.17
rrs 1472977 n.1132G>T non_coding_transcript_exon_variant 0.17
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.15
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.18
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.74
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.53
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.57
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.14
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.92
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.78
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.93
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.86
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.73
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.83
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.89
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.85
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.88
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.4
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.47
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.86
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.86
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.88
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.8
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.73
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.7
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.87
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.89
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.69
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.69
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.22
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.25
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.24
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.47
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.83
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.84
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.86
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.73
rrs 1473293 n.1449delA non_coding_transcript_exon_variant 0.56
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.62
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.78
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.81
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.22
rrl 1473384 n.-274A>G upstream_gene_variant 0.36
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.86
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.89
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.89
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.88
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.88
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.29
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.27
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.89
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.22
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.71
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.71
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.86
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.67
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.69
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.5
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.43
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.43
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.29
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.25
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.5
rrl 1474363 n.706A>T non_coding_transcript_exon_variant 0.25
rrl 1474365 n.708G>C non_coding_transcript_exon_variant 0.22
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.38
rrl 1474384 n.727C>G non_coding_transcript_exon_variant 0.25
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.62
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 0.29
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.25
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 0.18
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.3
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.75
rrl 1474483 n.826C>T non_coding_transcript_exon_variant 0.53
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.8
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.8
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.57
rrl 1474497 n.840G>A non_coding_transcript_exon_variant 0.53
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.2
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.19
rrl 1474506 n.849C>T non_coding_transcript_exon_variant 0.53
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.76
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.72
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.72
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.5
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.5
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.72
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.53
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.53
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.71
rrl 1474551 n.894G>A non_coding_transcript_exon_variant 0.52
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.58
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.82
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.88
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.79
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.84
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.74
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.87
rrl 1474709 n.1052G>A non_coding_transcript_exon_variant 0.89
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.89
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.78
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.9
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.79
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.16
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.86
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.8
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.85
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.92
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.66
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.8
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.88
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.2
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.82
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.92
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.79
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.91
rrl 1474869 n.1212G>C non_coding_transcript_exon_variant 0.14
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.69
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.88
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.7
rrl 1474933 n.1276A>G non_coding_transcript_exon_variant 0.46
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 0.46
rrl 1474946 n.1289C>T non_coding_transcript_exon_variant 0.29
rrl 1475016 n.1359C>T non_coding_transcript_exon_variant 0.43
rrl 1475018 n.1361G>C non_coding_transcript_exon_variant 0.43
rrl 1475026 n.1369G>C non_coding_transcript_exon_variant 0.43
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 0.43
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 0.43
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.5
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 0.6
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 0.6
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.5
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.5
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.57
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.33
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.36
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.44
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.58
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.44
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.21
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.36
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.25
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.57
rrl 1475752 n.2095C>A non_coding_transcript_exon_variant 0.29
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.5
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.38
rrl 1475776 n.2119G>T non_coding_transcript_exon_variant 0.3
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.78
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.32
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.35
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.34
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.33
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.34
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.26
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.22
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.17
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.91
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.77
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.6
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.53
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.9
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.9
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.73
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.91
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.9
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.92
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.76
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.9
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.17
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.88
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.81
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.86
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.25
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.84
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.35
rrl 1475995 n.2338G>C non_coding_transcript_exon_variant 0.41
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.81
rrl 1475998 n.2341C>G non_coding_transcript_exon_variant 0.67
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.7
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.38
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.87
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.6
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.5
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.5
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.5
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.67
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.67
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.67
rrl 1476126 n.2469C>T non_coding_transcript_exon_variant 0.25
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.46
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.31
rrl 1476135 n.2478T>C non_coding_transcript_exon_variant 0.5
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.7
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.76
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.76
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.84
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.84
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.84
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.86
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.86
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.81
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.79
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.79
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.79
rrl 1476214 n.2557G>C non_coding_transcript_exon_variant 0.82
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.86
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.93
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.85
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.91
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.9
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.96
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.9
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.97
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.95
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.93
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.95
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.96
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.96
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.95
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.92
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.86
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.93
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.96
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.96
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.92
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.92
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.93
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.93
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.93
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.91
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.91
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.9
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.9
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.89
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.97
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.97
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.17
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.96
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.97
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.79
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.15
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.72
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.2
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.9
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.77
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.92
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.73
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.88
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.29
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.76
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.53
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.71
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.35
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.39
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.69
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.33
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.29
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.31
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.69
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.38
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.45
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.3
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.25
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.38
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.43
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.43
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.43
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.33
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.43
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.29
rpsA 1833949 c.408T>C synonymous_variant 0.19
rpsA 1833970 c.429G>C synonymous_variant 0.24
rpsA 1833976 c.435C>T synonymous_variant 0.13
rpsA 1834000 c.459G>C synonymous_variant 0.19
rpsA 1834009 c.468C>T synonymous_variant 0.19
rpsA 1834012 c.471G>C synonymous_variant 0.13
rpsA 1834015 c.474G>C synonymous_variant 0.14
rpsA 1834024 c.483G>C synonymous_variant 0.14
rpsA 1834025 p.Gln162Ala missense_variant 0.14
rpsA 1834039 c.498C>T synonymous_variant 0.15
rpsA 1834040 p.Lys167Arg missense_variant 0.15
rpsA 1834051 c.510G>A synonymous_variant 0.17
rpsA 1834054 c.513C>G synonymous_variant 0.17
rpsA 1834069 c.528G>C synonymous_variant 0.2
rpsA 1834093 c.552G>C synonymous_variant 0.2
rpsA 1834234 c.693G>C synonymous_variant 0.35
rpsA 1834240 c.699T>C synonymous_variant 0.35
rpsA 1834249 c.708T>C synonymous_variant 0.4
rpsA 1834261 c.720A>G synonymous_variant 0.46
rpsA 1834264 c.723G>C synonymous_variant 0.46
rpsA 1834294 c.753G>C synonymous_variant 0.42
rpsA 1834298 p.Gln253Glu missense_variant 0.5
rpsA 1834303 c.762T>C synonymous_variant 0.15
rpsA 1834306 c.765T>C synonymous_variant 0.54
rpsA 1834307 p.Asp256Gln missense_variant 0.54
rpsA 1834312 c.771G>A synonymous_variant 0.47
rpsA 1834327 c.786G>T synonymous_variant 0.47
rpsA 1834345 c.804C>T synonymous_variant 0.43
rpsA 1834348 c.807T>C synonymous_variant 0.42
rpsA 1834354 c.813G>C synonymous_variant 0.36
rpsA 1834361 c.820T>C synonymous_variant 0.33
rpsA 1834366 c.825A>C synonymous_variant 0.18
rpsA 1834375 c.834G>C synonymous_variant 0.25
rpsA 1834378 c.837T>C synonymous_variant 0.25
rpsA 1834387 c.846C>T synonymous_variant 0.2
rpsA 1834411 c.870T>C synonymous_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154119 p.Gly665Cys missense_variant 0.4
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168988 c.1624delA frameshift_variant 0.29
Rv1979c 2222788 p.Ala126Asp missense_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288893 c.349C>T synonymous_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
eis 2714425 p.Ala303Val missense_variant 0.33
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ahpC 2726115 c.-78C>A upstream_gene_variant 1.0
folC 2746884 p.Pro239Ser missense_variant 0.33
pepQ 2859878 p.Leu181Phe missense_variant 0.33
Rv2752c 3065791 p.Thr134Asn missense_variant 0.5
thyA 3074648 c.-177T>G upstream_gene_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3840955 c.465delC frameshift_variant 0.5
embC 4240493 p.Gly211Cys missense_variant 0.2
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243347 p.Thr39Pro missense_variant 0.33
whiB6 4338316 p.Ser69Tyr missense_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407681 c.521delA frameshift_variant 1.0