Run ID: 53250661-7b58-41ce-9786-3d3ca03fa60d
Sample name:
Date: 25-04-2024 17:04:24
Number of reads: 2273957
Percentage reads mapped: 95.67
Median coverage: 69
Strain:
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | ||||
| amikacin | ||||
| kanamycin | ||||
| capreomycin | ||||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 5101 | c.-139G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5161 | c.-79C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5326 | c.87T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5341 | c.102T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5353 | c.114T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5431 | c.192A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5440 | c.201A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5452 | c.213G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5524 | c.285C>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5878 | c.639G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5983 | c.744C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5992 | c.753T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6001 | c.762G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6049 | c.810G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6052 | c.813T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6056 | p.Ser273Gly | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6094 | c.855C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6151 | c.912C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6277 | c.1038C>A | synonymous_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6445 | c.-857C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6472 | c.-830G>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6502 | c.-800T>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6508 | c.-794A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6550 | c.-752A>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6559 | c.-743C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6562 | c.-740G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6571 | c.-731T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6574 | c.-728C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6745 | c.-557T>A | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6754 | c.-548C>T | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6793 | c.-509T>C | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6797 | p.Gly520Ser | missense_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6841 | c.-461T>C | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6856 | c.-446T>C | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6859 | c.-443T>C | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6862 | c.-440C>G | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6865 | c.-437G>C | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6878 | c.-424T>C | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6881 | c.-421T>C | upstream_gene_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6892 | c.-410C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6904 | c.-398C>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6926 | c.-376T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6934 | c.-368A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6982 | c.-320A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 7013 | p.Glu592Gln | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7060 | c.-242T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7078 | c.-224A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7093 | c.-209T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7120 | c.-182T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7141 | c.-161T>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7144 | c.-158A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7207 | c.-95C>T | upstream_gene_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7216 | c.-86G>T | upstream_gene_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7237 | c.-65C>T | upstream_gene_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7271 | c.-30_-28delACC | upstream_gene_variant | 0.96 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7276 | c.-26_-25insTC | upstream_gene_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7317 | c.16T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7335 | p.Leu12Val | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7349 | c.48A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7409 | c.108C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7460 | c.159C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7493 | c.192C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7502 | c.201C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7505 | c.204C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7661 | c.360C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7709 | c.408G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7728 | c.427A>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7760 | c.459C>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7814 | c.513C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 0.96 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 0.96 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7868 | c.567C>T | synonymous_variant | 0.96 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7895 | c.594C>T | synonymous_variant | 0.94 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8054 | c.753T>C | synonymous_variant | 0.96 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8204 | c.903C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 0.97 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 0.99 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8453 | c.1152A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8507 | c.1206C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8552 | c.1251C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8566 | p.Ile422Asn | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8573 | c.1272G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8627 | c.1326C>A | synonymous_variant | 0.99 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8660 | c.1359C>T | synonymous_variant | 0.99 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8723 | c.1422G>A | synonymous_variant | 0.99 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8849 | c.1548C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9038 | c.1737C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9101 | c.1800A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9168 | c.1867C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9314 | c.2013G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9315 | c.2014C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9318 | c.2017C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9485 | c.2184A>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9506 | c.2205C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9548 | c.2247T>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9560 | c.2259C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9635 | c.2334T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9644 | c.2343T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9650 | c.2349G>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9665 | c.2364A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9674 | c.2373T>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9716 | c.2415T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9740 | c.2439G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| fgd1 | 490666 | c.-117G>T | upstream_gene_variant | 1.0 | delamanid | |
| fgd1 | 490678 | c.-105_-104insG | upstream_gene_variant | 1.0 | delamanid | |
| fgd1 | 490687 | c.-96T>C | upstream_gene_variant | 1.0 | delamanid | |
| fgd1 | 490720 | c.-63T>G | upstream_gene_variant | 0.56 | delamanid | |
| fgd1 | 490734 | c.-49A>T | upstream_gene_variant | 0.97 | delamanid | |
| fgd1 | 490744 | c.-39T>C | upstream_gene_variant | 0.13 | delamanid | |
| fgd1 | 490745 | c.-38G>C | upstream_gene_variant | 0.13 | delamanid | |
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | delamanid | |
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | delamanid | |
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | delamanid | |
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | delamanid | |
| fgd1 | 491310 | c.528C>T | synonymous_variant | 1.0 | delamanid | |
| fgd1 | 491406 | p.Met208Ile | missense_variant | 1.0 | delamanid | |
| fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | delamanid | |
| mshA | 576757 | c.1410C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619766 | c.-125A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| ccsA | 620256 | c.366C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| ccsA | 620257 | p.Ile123Ala | missense_variant | 1.0 | capreomycin | |
| amikacin | Uncertain significance | |||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| ccsA | 620490 | c.600A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| ccsA | 620808 | c.918T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| rpoB | 759742 | c.-65G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 760034 | c.228A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760253 | c.447T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760697 | c.891G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760988 | c.1182C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 761051 | c.1245G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761078 | c.1272C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761210 | c.1404C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761282 | c.1476C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761438 | c.1632G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761603 | c.1797C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762024 | p.Val740Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762089 | c.2283G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762251 | c.2445G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 762278 | c.2472C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762608 | c.-762C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762782 | c.-588T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762932 | c.-438G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762959 | c.-411G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762971 | c.-399G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762980 | c.-390T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763031 | c.-339T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763040 | c.-330C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763064 | c.-306G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763067 | c.-303C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763185 | c.-185_-183delCTCinsTTG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763217 | c.-153G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763241 | c.-129G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763283 | c.-87T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763284 | c.-86C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763289 | c.-81C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763327 | c.-43G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763375 | c.6C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763441 | c.72C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764134 | c.765C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764152 | c.783C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764159 | c.790C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764287 | c.918C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764293 | c.924G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764506 | c.1137C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764510 | c.1141C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764533 | c.1164C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764563 | c.1194G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764578 | c.1209C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764632 | c.1263T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766222 | c.2853T>C | synonymous_variant | 1.0 | rifampicin | |
| mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775670 | c.2811C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775682 | c.2799C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775685 | c.2794_2796delCTCinsTTG | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775691 | c.2790G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775748 | c.2733T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775784 | c.2697G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775856 | c.2625T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775905 | p.Lys859Arg | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775991 | c.2490G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775997 | c.2484T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776047 | c.2434C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776137 | p.Ser782Ala | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776147 | c.2334C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776159 | c.2322T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776163 | p.Thr773Ser | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776207 | c.2274G>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776218 | p.Ala755Thr | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776230 | c.2251T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776231 | c.2250G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776292 | p.Ala730Glu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776312 | c.2169A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776336 | c.2145G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776340 | p.His714Arg | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776342 | c.2139G>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776387 | c.2094T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776396 | c.2085T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776438 | c.2043T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776459 | c.2022G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776480 | c.2001C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776507 | c.1974C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776564 | c.1917C>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776576 | c.1905C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776581 | c.1900C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776602 | c.1879C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776654 | c.1827A>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776684 | c.1797G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776789 | c.1692C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776792 | c.1689T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776808 | p.Thr558Gln | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776816 | c.1665T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776902 | p.Asn527Asp | missense_variant | 0.99 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776910 | p.Glu524Ala | missense_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776942 | c.1539A>G | synonymous_variant | 0.95 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776984 | c.1497C>T | synonymous_variant | 0.95 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776993 | c.1488A>G | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777023 | c.1458G>C | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777041 | c.1440G>A | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777056 | c.1425G>C | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777060 | p.Ala474Gly | missense_variant | 0.95 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777110 | c.1371T>C | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777116 | c.1365C>T | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777308 | c.1173C>A | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777350 | c.1131G>C | synonymous_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777368 | c.1113G>A | synonymous_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777404 | c.1077C>G | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777431 | c.1050A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777448 | p.Ile345Val | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777455 | c.1026G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777473 | c.1008T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777497 | c.984A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777512 | c.969T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777554 | c.927C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777591 | p.Ser297Gln | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777593 | c.888G>A | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777596 | c.885G>C | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777605 | c.876C>G | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777617 | c.864A>G | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777626 | c.855C>T | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777683 | c.798C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777737 | c.744T>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777743 | p.Gly246Trp | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777763 | c.718C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777802 | p.Ile227Leu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777803 | c.678C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777823 | c.658C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777826 | c.655T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777842 | c.639C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777855 | p.Ala209Met | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777872 | c.609T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777875 | c.606T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777907 | c.574C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777944 | c.537A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777958 | p.Arg175Ser | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777959 | p.Glu174Asp | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777965 | c.516C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777974 | c.507C>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778022 | c.-968G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778057 | p.Ser142Gly | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778070 | c.-920G>C | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778082 | c.-908T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778088 | c.-902C>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778119 | p.Thr121Asn | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778132 | p.Gln117Lys | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778136 | p.Arg115Lys | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778140 | p.Gly114Asp | missense_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778163 | c.-827A>G | upstream_gene_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778169 | c.-821G>C | upstream_gene_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778181 | c.-809C>T | upstream_gene_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778185 | p.Arg99Gln | missense_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778226 | c.-764T>G | upstream_gene_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778229 | c.-761C>T | upstream_gene_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778247 | p.Ile78Met | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778274 | c.-716T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778304 | p.Ile59Met | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778310 | c.-680T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778318 | p.Thr55Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778325 | c.-665T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778335 | p.Thr49Gly | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778340 | c.-650G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778349 | p.Ala44Val | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778370 | c.-620A>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778394 | c.-596A>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778397 | c.-593G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778406 | c.-584G>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778434 | p.Asp16Thr | missense_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 778436 | c.-554G>C | upstream_gene_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778449 | p.Gly11Asp | missense_variant | 0.99 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778470 | p.Gln4Arg | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778487 | p.Lys140Arg | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778507 | c.-27C>T | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778510 | p.Asp132Asn | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778573 | c.-93C>G | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778578 | p.Thr110Ala | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778654 | c.-174A>G | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778675 | c.-195G>A | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778717 | c.-237C>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778729 | p.Glu59Asp | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778737 | p.Glu57Lys | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778784 | p.Pro41Gln | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778949 | c.-469G>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779015 | p.Gln9Arg | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779017 | p.Met10Val | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779026 | p.Glu13Lys | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779052 | c.-572T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779076 | c.-596G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779088 | c.-608A>T | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779100 | c.-620A>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779103 | c.-623T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779142 | c.-662C>T | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779148 | c.-668C>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779155 | c.-675G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779166 | c.-686C>T | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779167 | c.-687G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779206 | p.Met73Leu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779220 | c.-740A>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779223 | c.-743C>A | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779264 | p.Tyr92Phe | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779268 | c.-788G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779286 | c.-806A>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779295 | c.-815A>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779298 | c.-818G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779307 | c.-827T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779310 | c.-830G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779319 | c.-839T>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779328 | p.Glu113Asp | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779335 | p.Asp116His | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779349 | c.-869C>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779357 | p.Arg123Lys | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779361 | c.-881C>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779370 | c.-890G>A | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779380 | p.Gln131Glu | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779388 | c.-908G>A | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779391 | c.-911T>C | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779412 | c.-932A>G | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779421 | c.-941T>G | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779433 | p.Asn148Lys | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779461 | p.Ser158Gly | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 779469 | c.-989T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779480 | p.Asp164Gly | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpR5 | 779486 | c.497G>T | stop_lost&splice_region_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779505 | c.-601_-600insC | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779516 | c.-611C>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779539 | c.-634C>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779606 | c.-701C>T | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779612 | c.-707G>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779623 | c.-718C>T | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779630 | c.-725T>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779634 | c.-730_-729delGTinsAC | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779639 | c.-734C>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779662 | c.-757G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779677 | c.-772G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779678 | c.-773T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779686 | c.-781G>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781484 | c.-76A>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>G | synonymous_variant | 1.0 | streptomycin | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | Uncertain significance |
| rplC | 800850 | c.42G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801109 | p.Leu101Val | missense_variant | 1.0 | linezolid | |
| fbiC | 1302914 | c.-17A>G | upstream_gene_variant | 1.0 | delamanid | |
| fbiC | 1305405 | c.2475A>G | synonymous_variant | 1.0 | delamanid | |
| fbiC | 1305444 | c.2514A>G | synonymous_variant | 1.0 | delamanid | |
| fbiC | 1305457 | p.Pro843Ala | missense_variant | 1.0 | delamanid | |
| fbiC | 1305486 | c.2556C>T | synonymous_variant | 1.0 | delamanid | |
| Rv1258c | 1406110 | p.Ile411Val | missense_variant | 0.98 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406189 | c.1152A>T | synonymous_variant | 0.98 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406257 | c.1084T>C | synonymous_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406404 | p.Val313Ile | missense_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406434 | p.Met303Val | missense_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406466 | p.Ser292Leu | missense_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | Uncertain significance | |||||
| Rv1258c | 1406492 | p.Ile283Met | missense_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406519 | c.822A>G | synonymous_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406543 | c.798G>C | synonymous_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406648 | c.693T>C | synonymous_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406759 | p.Glu194Asp | missense_variant | 1.0 | streptomycin | |
| pyrazinamide | Uncertain significance | |||||
| isoniazid | ||||||
| Rv1258c | 1406765 | c.576A>G | synonymous_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1406944 | p.Ala133Thr | missense_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1407045 | p.Asp99Gly | missense_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1407057 | p.Gly95Glu | missense_variant | 0.96 | streptomycin | Uncertain significance |
| pyrazinamide | ||||||
| isoniazid | Uncertain significance | |||||
| Rv1258c | 1407370 | c.-30G>A | upstream_gene_variant | 0.98 | streptomycin | Uncertain significance |
| pyrazinamide | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv1258c | 1407446 | c.-106G>C | upstream_gene_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| Rv1258c | 1407534 | c.-194C>G | upstream_gene_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| embR | 1416532 | c.816C>T | synonymous_variant | 1.0 | ethambutol | |
| embR | 1416538 | c.810T>C | synonymous_variant | 0.98 | ethambutol | |
| embR | 1416994 | c.354A>G | synonymous_variant | 1.0 | ethambutol | |
| embR | 1417108 | c.240T>C | synonymous_variant | 0.99 | ethambutol | |
| embR | 1417260 | p.Ser30Thr | missense_variant | 1.0 | ethambutol | |
| embR | 1417294 | c.54A>G | synonymous_variant | 1.0 | ethambutol | |
| embR | 1417413 | c.-66G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embR | 1417464 | c.-117C>T | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embR | 1417493 | c.-146T>G | upstream_gene_variant | 1.0 | ethambutol | |
| embR | 1417507 | c.-160A>T | upstream_gene_variant | 1.0 | ethambutol | |
| embR | 1417530 | c.-183T>G | upstream_gene_variant | 1.0 | ethambutol | |
| embR | 1417543 | c.-196T>C | upstream_gene_variant | 1.0 | ethambutol | |
| atpE | 1460897 | c.-148A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1461261 | c.217C>T | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471811 | n.-35A>G | upstream_gene_variant | 0.98 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472042 | n.197T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472043 | n.198T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473094 | n.1249T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.99 | linezolid | |
| rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1474023 | n.366T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474089 | n.432C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474275 | n.618T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474432 | n.775C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474964 | n.1307T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475254 | n.1597C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| fabG1 | 1673321 | c.-119A>G | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833352 | c.-190C>T | upstream_gene_variant | 0.96 | pyrazinamide | |
| rpsA | 1833381 | c.-161T>C | upstream_gene_variant | 0.96 | pyrazinamide | |
| rpsA | 1833471 | c.-71_-70insC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833512 | c.-29delC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833568 | c.27G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833596 | c.55_56delAGinsTC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833865 | c.324G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833871 | c.330G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833883 | c.342C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833904 | c.363G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833940 | c.399C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833953 | c.412C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833976 | c.435C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834241 | c.700C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834361 | c.820T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834396 | c.855G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834402 | c.861C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834438 | c.897C>A | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834474 | c.933C>G | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834477 | c.936C>T | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834486 | c.945G>A | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834495 | c.954G>A | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834504 | c.963G>A | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834513 | c.972C>G | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834522 | c.981C>A | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834528 | c.987T>G | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834561 | c.1020C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834669 | c.1128G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834810 | c.1269C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834831 | c.1290G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834948 | c.1407G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834954 | c.1413G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | |
| ndh | 2101676 | p.Ala456Gly | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2101696 | c.1347C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2101777 | c.1266C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2101804 | c.1239T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102164 | c.879A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102254 | p.Asp263Asn | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102302 | c.741G>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102366 | p.Ala226Glu | missense_variant | 0.98 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| ndh | 2102389 | c.654G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102560 | c.483C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102791 | c.252A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102815 | c.228G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103001 | c.42G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103005 | p.Arg13His | missense_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| ndh | 2103012 | p.Pro11Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103060 | c.-18C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103173 | c.-132_-131insG | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103239 | c.-197T>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| katG | 2153989 | p.Val708Ala | missense_variant | 1.0 | isoniazid | |
| katG | 2154055 | p.Lys686Thr | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2154126 | c.1986C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2154190 | p.Leu641Ser | missense_variant | 1.0 | isoniazid | |
| katG | 2154435 | c.1677T>C | synonymous_variant | 0.98 | isoniazid | |
| katG | 2154531 | c.1581A>G | synonymous_variant | 0.98 | isoniazid | |
| katG | 2154594 | c.1518G>A | synonymous_variant | 0.98 | isoniazid | |
| katG | 2154645 | c.1467C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2154696 | c.1416A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2154733 | p.Ser460Asn | missense_variant | 1.0 | isoniazid | |
| katG | 2154738 | c.1374T>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2154758 | p.Glu452Gln | missense_variant | 1.0 | isoniazid | |
| katG | 2154759 | c.1353C>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2154777 | p.Val445Ala | missense_variant | 1.0 | isoniazid | |
| katG | 2154783 | c.1329T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2154792 | c.1320T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2154822 | c.1290G>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2154842 | p.Ala424Thr | missense_variant | 1.0 | isoniazid | |
| katG | 2154843 | c.1269T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155190 | p.Thr308Ala | missense_variant | 1.0 | isoniazid | |
| katG | 2155233 | c.879G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155326 | c.786A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155491 | c.621T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155785 | c.327T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155971 | c.141A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2156008 | p.Asn35Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2156055 | c.57C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2156061 | c.51C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2156287 | c.-176T>C | upstream_gene_variant | 0.98 | isoniazid | |
| katG | 2156290 | c.-179C>G | upstream_gene_variant | 0.98 | isoniazid | |
| PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| PPE35 | 2169717 | p.Asn299Ile | missense_variant | 0.98 | pyrazinamide | |
| PPE35 | 2170232 | c.381T>C | synonymous_variant | 0.98 | pyrazinamide | |
| PPE35 | 2170394 | c.219G>C | synonymous_variant | 1.0 | pyrazinamide | |
| PPE35 | 2170485 | p.Val43Ala | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2170694 | c.-82T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| PPE35 | 2170720 | c.-108A>G | upstream_gene_variant | 1.0 | pyrazinamide | Uncertain significance |
| Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 0.99 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| Rv1979c | 2222357 | p.Thr270Ala | missense_variant | 0.98 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| pncA | 2289104 | c.138A>G | synonymous_variant | 1.0 | pyrazinamide | |
| kasA | 2517969 | c.-146C>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518019 | c.-96A>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518265 | p.Val51Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518279 | c.165T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518282 | c.168A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518283 | p.Ala57Pro | missense_variant | 1.0 | isoniazid | |
| kasA | 2518297 | c.183C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519062 | c.948T>G | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2519104 | c.990T>C | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2519107 | c.993T>C | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2519110 | p.Asp332Glu | missense_variant | 0.98 | isoniazid | |
| kasA | 2519260 | c.1146T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519266 | c.1152C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519281 | c.1167G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519287 | c.1173T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519295 | p.Tyr394Phe | missense_variant | 1.0 | isoniazid | |
| kasA | 2519299 | c.1185C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519302 | c.1188C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519305 | c.1191A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519308 | c.1194C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519311 | c.1197C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519329 | c.1215C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519332 | c.1218C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519344 | c.1230G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519347 | c.1233T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519359 | c.1245T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519364 | c.1250G>A | splice_region_variant&stop_retained_variant | 1.0 | isoniazid | |
| eis | 2715419 | c.-88delG | upstream_gene_variant | 1.0 | kanamycin | |
| amikacin | ||||||
| ahpC | 2726572 | p.Ala127Val | missense_variant | 0.8 | isoniazid | |
| folC | 2747204 | p.Ala132Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747572 | c.27T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747575 | c.24G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747628 | c.-30G>C | upstream_gene_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747631 | c.-33C>G | upstream_gene_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747691 | c.-93A>G | upstream_gene_variant | 1.0 | para-aminosalicylic_acid | |
| pepQ | 2859364 | p.Pro352Leu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859408 | c.1011C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859490 | p.Val310Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859513 | c.906A>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859553 | p.His289Arg | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859591 | c.828A>G | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859604 | p.Gly272Glu | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859636 | c.783G>A | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859771 | c.648T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859777 | p.Val214Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859834 | c.585T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859861 | c.558C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859864 | c.555T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859943 | p.Ala159Asp | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859984 | c.435A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860029 | c.390A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860359 | c.60T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860364 | c.55T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860446 | c.-28T>A | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860543 | c.-125A>G | upstream_gene_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| ribD | 2986929 | p.Leu31Phe | missense_variant | 1.0 | para-aminosalicylic_acid | |
| Rv2752c | 3064516 | c.1676A>G | splice_region_variant&stop_retained_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3064554 | c.1638C>T | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3064838 | c.1354T>C | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3064857 | c.1335C>T | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065111 | c.1081A>C | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065178 | c.1014G>A | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065205 | c.987T>C | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065322 | c.870C>T | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065331 | c.861C>A | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065442 | c.750T>C | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065795 | p.Ser133Arg | missense_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066066 | c.126T>C | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066083 | c.109C>T | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066111 | c.81C>T | synonymous_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066153 | p.Ser13Ala | missense_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066166 | p.Gly9His | missense_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066177 | c.15T>C | synonymous_variant | 0.27 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066208 | c.-28_-18delTAAAGGTGAGC | upstream_gene_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066243 | c.-52C>T | upstream_gene_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066288 | c.-97G>C | upstream_gene_variant | 0.98 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066335 | c.-144T>C | upstream_gene_variant | 0.98 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066336 | c.-145C>T | upstream_gene_variant | 0.98 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066347 | c.-156T>G | upstream_gene_variant | 0.98 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066996 | c.-805T>C | upstream_gene_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3067051 | c.-860G>C | upstream_gene_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| thyX | 3067239 | p.Ala236Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073704 | c.768G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073782 | c.690A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074160 | c.312A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074529 | c.-58G>C | upstream_gene_variant | 1.0 | para-aminosalicylic_acid | |
| ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
| ald | 3086969 | c.150C>T | synonymous_variant | 1.0 | cycloserine | |
| fbiD | 3339049 | c.-69C>T | upstream_gene_variant | 1.0 | delamanid | |
| fbiD | 3339402 | c.285C>T | synonymous_variant | 0.98 | delamanid | |
| fbiD | 3339568 | c.451C>T | synonymous_variant | 1.0 | delamanid | |
| Rv3083 | 3448474 | c.-30G>T | upstream_gene_variant | 1.0 | ethionamide | |
| Rv3083 | 3448495 | c.-9G>T | upstream_gene_variant | 0.97 | ethionamide | |
| Rv3083 | 3448560 | c.57G>A | synonymous_variant | 0.98 | ethionamide | |
| Rv3083 | 3448606 | c.103C>T | synonymous_variant | 0.98 | ethionamide | |
| Rv3083 | 3448611 | c.108A>G | synonymous_variant | 0.98 | ethionamide | |
| Rv3083 | 3448642 | c.139T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3448972 | p.His157Asp | missense_variant | 0.98 | ethionamide | |
| Rv3083 | 3449004 | c.501G>A | synonymous_variant | 0.98 | ethionamide | |
| Rv3083 | 3449028 | c.525T>C | synonymous_variant | 0.98 | ethionamide | |
| Rv3083 | 3449029 | p.Ser176Ala | missense_variant | 0.98 | ethionamide | |
| Rv3083 | 3449109 | c.606C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449139 | c.636A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449148 | c.645G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449237 | p.Arg245Lys | missense_variant | 1.0 | ethionamide | |
| Rv3083 | 3449253 | c.750C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449263 | p.Leu254Val | missense_variant | 1.0 | ethionamide | |
| Rv3083 | 3449290 | p.Lys263Gln | missense_variant | 1.0 | ethionamide | |
| Rv3083 | 3449305 | c.802T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449328 | c.825C>A | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449400 | c.897C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449412 | c.909C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449421 | c.918T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449481 | c.978G>A | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449545 | c.1042C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449622 | c.1119T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449652 | c.1149T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449683 | p.Ser394Ala | missense_variant | 1.0 | ethionamide | |
| Rv3083 | 3449728 | c.1225C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449758 | p.Thr419Ala | missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv3083 | 3449778 | c.1275T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449802 | c.1299T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449820 | c.1317G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449832 | c.1329T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449835 | c.1332G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449868 | c.1365C>A | synonymous_variant | 0.98 | ethionamide | |
| Rv3083 | 3449877 | c.1374T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv3083 | 3449885 | p.Arg461Lys | missense_variant | 1.0 | ethionamide | |
| Rv3083 | 3449917 | p.Ile472Val | missense_variant | 1.0 | ethionamide | |
| Rv3083 | 3449940 | c.1437T>C | synonymous_variant | 1.0 | ethionamide | |
| fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| fprA | 3474309 | c.303C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| fprA | 3474697 | p.Asp231Asn | missense_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| fprA | 3475159 | p.Asn385Asp | missense_variant | 1.0 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| Rv3236c | 3612250 | c.867A>G | synonymous_variant | 1.0 | pyrazinamide | |
| fbiB | 3642254 | c.720G>A | synonymous_variant | 1.0 | delamanid | |
| fbiB | 3642467 | c.933T>C | synonymous_variant | 1.0 | delamanid | |
| alr | 3840226 | p.Thr399Ala | missense_variant | 1.0 | cycloserine | |
| alr | 3840368 | c.1053C>T | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840527 | c.894A>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840719 | c.702A>G | synonymous_variant | 0.95 | cycloserine | |
| alr | 3840796 | p.Asp209Asn | missense_variant | 0.96 | cycloserine | |
| alr | 3840914 | c.507G>C | synonymous_variant | 0.96 | cycloserine | |
| alr | 3840994 | p.His143Asp | missense_variant | 1.0 | cycloserine | |
| alr | 3841112 | c.309T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841116 | p.Ala102Gly | missense_variant | 1.0 | cycloserine | |
| alr | 3841172 | c.249A>C | synonymous_variant | 0.99 | cycloserine | |
| alr | 3841232 | c.189G>A | synonymous_variant | 0.98 | cycloserine | |
| alr | 3841419 | p.Val1Ala | missense_variant | 1.0 | cycloserine | |
| alr | 3841524 | c.-104G>A | upstream_gene_variant | 1.0 | cycloserine | |
| alr | 3841531 | c.-111A>G | upstream_gene_variant | 1.0 | cycloserine | |
| alr | 3841532 | c.-112A>G | upstream_gene_variant | 1.0 | cycloserine | |
| alr | 3841539 | c.-119C>T | upstream_gene_variant | 1.0 | cycloserine | |
| alr | 3841546 | c.-126C>G | upstream_gene_variant | 1.0 | cycloserine | |
| alr | 3841568 | c.-148G>A | upstream_gene_variant | 1.0 | cycloserine | |
| rpoA | 3877746 | c.762G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877886 | c.622C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3877928 | c.580C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878406 | c.102G>C | synonymous_variant | 1.0 | rifampicin | |
| ddn | 3986805 | c.-39G>C | upstream_gene_variant | 0.98 | delamanid | |
| ddn | 3987050 | c.207C>T | synonymous_variant | 1.0 | delamanid | |
| ddn | 3987227 | c.384G>A | synonymous_variant | 1.0 | delamanid | |
| ddn | 3987257 | c.414C>G | synonymous_variant | 1.0 | delamanid | |
| clpC1 | 4039811 | c.894C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040435 | c.270G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040874 | c.-171_-170insT | upstream_gene_variant | 1.0 | pyrazinamide | |
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4243354 | p.Ala41Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4243685 | p.Asp151Glu | missense_variant | 1.0 | ethambutol | |
| embA | 4243690 | p.Met153Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4244312 | c.1080T>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245023 | c.1791A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247646 | p.Glu378Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248206 | p.Ser565Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248892 | c.2379A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249754 | p.Gly1081Cys | missense_variant | 0.98 | ethambutol | |
| aftB | 4267987 | p.Arg284Ser | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| aftB | 4268331 | p.Gln169Pro | missense_variant | 1.0 | capreomycin | |
| amikacin | Uncertain significance | |||||
| ubiA | 4269387 | p.Glu149Asp | missense_variant | 0.94 | ethambutol | Uncertain significance |
| aftB | 4269606 | c.-770T>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| ubiA | 4269811 | p.Gln8Arg | missense_variant | 1.0 | ethambutol | Uncertain significance |
| ethA | 4327546 | c.-74_-73insC | upstream_gene_variant | 1.0 | ethionamide | |
| whiB6 | 4338279 | c.243T>C | synonymous_variant | 1.0 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| whiB6 | 4338627 | c.-106T>C | upstream_gene_variant | 1.0 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338660 | c.-139G>A | upstream_gene_variant | 1.0 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338664 | c.-143C>T | upstream_gene_variant | 1.0 | streptomycin | |
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| whiB6 | 4338666 | c.-145G>A | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338670 | c.-149A>C | upstream_gene_variant | 1.0 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| gid | 4407549 | p.Met218Ile | missense_variant | 1.0 | streptomycin | |
| gid | 4407569 | p.Ala212Pro | missense_variant | 1.0 | streptomycin | |
| gid | 4407582 | c.621T>C | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407690 | c.513A>G | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407705 | c.498G>T | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407807 | c.396C>T | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407939 | c.264A>C | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407945 | c.258C>A | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407951 | c.252G>T | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407969 | c.234A>G | synonymous_variant | 1.0 | streptomycin | |
| gid | 4408008 | c.195C>G | synonymous_variant | 1.0 | streptomycin | |
| gid | 4408089 | c.114C>T | synonymous_variant | 0.98 | streptomycin | |
| gid | 4408092 | c.111A>C | synonymous_variant | 1.0 | streptomycin | |
| gid | 4408127 | c.76T>C | synonymous_variant | 1.0 | streptomycin | |
| gid | 4408153 | p.Gly17Asp | missense_variant | 1.0 | streptomycin | |
| gid | 4408164 | c.39A>T | synonymous_variant | 1.0 | streptomycin | |
| gid | 4408167 | c.36C>T | synonymous_variant | 1.0 | streptomycin | |
| gid | 4408223 | c.-21C>T | upstream_gene_variant | 1.0 | streptomycin | |
| gid | 4408228 | c.-28_-27delCA | upstream_gene_variant | 0.98 | streptomycin | |
| gid | 4408285 | c.-83C>T | upstream_gene_variant | 1.0 | streptomycin | |
| gid | 4408302 | c.-100A>G | upstream_gene_variant | 1.0 | streptomycin | |
| gid | 4408306 | c.-104C>T | upstream_gene_variant | 1.0 | streptomycin | |
| gid | 4408310 | c.-109_-108insAACC | upstream_gene_variant | 1.0 | streptomycin | |
| gid | 4408331 | c.-129C>T | upstream_gene_variant | 1.0 | streptomycin | |
| gid | 4408355 | c.-153A>G | upstream_gene_variant | 1.0 | streptomycin | |
| gid | 4408448 | c.-246A>G | upstream_gene_variant | 1.0 | streptomycin | |
| gyrA | 9817 | c.2517_*53delANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN | frameshift_variant&stop_lost&splice_region_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin |
