TB-Profiler

Lineage	Family	RDs	Frequency
lineage4	Euro-American	None	1.0
lineage4.9	Euro-American (H37Rv-like)	None	1.0

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
rrs	1472733	n.888G>A	non_coding_transcript_exon_variant	0.58	streptomycin	Uncertain significance	Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
rpoB	762879	p.Met1025Leu	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	762887	c.3081G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762896	c.-474G>C	upstream_gene_variant	0.5	rifampicin
rpoC	762926	c.-444C>G	upstream_gene_variant	0.75	rifampicin
rpoB	762929	c.3123G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762932	c.-438G>C	upstream_gene_variant	0.67	rifampicin
rpoC	762938	c.-432G>C	upstream_gene_variant	0.75	rifampicin
rpoC	762947	c.-423C>G	upstream_gene_variant	0.75	rifampicin
rpoB	762962	c.3156C>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoC	762971	c.-399G>C	upstream_gene_variant	1.0	rifampicin
rrs	1471896	n.51T>C	non_coding_transcript_exon_variant	0.68	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1471900	n.55C>T	non_coding_transcript_exon_variant	0.68	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471911	n.66C>A	non_coding_transcript_exon_variant	0.77	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472078	n.233C>T	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	0.93	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472122	n.277G>T	non_coding_transcript_exon_variant	0.62	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472123	n.278A>T	non_coding_transcript_exon_variant	0.77	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472124	n.279C>T	non_coding_transcript_exon_variant	0.88	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472150	n.305T>A	non_coding_transcript_exon_variant	0.57	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472150	n.305T>G	non_coding_transcript_exon_variant	0.43	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472151	n.306C>A	non_coding_transcript_exon_variant	0.45	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472155	n.310C>T	non_coding_transcript_exon_variant	0.83	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472160	n.315C>T	non_coding_transcript_exon_variant	0.45	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472172	n.327T>C	non_coding_transcript_exon_variant	0.38	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472225	n.380C>A	non_coding_transcript_exon_variant	0.35	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472251	n.406G>A	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472258	n.413A>G	non_coding_transcript_exon_variant	0.37	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472259	n.414C>A	non_coding_transcript_exon_variant	0.73	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472285	n.440A>G	non_coding_transcript_exon_variant	0.88	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472338	n.493A>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472344	n.499C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472379	n.534T>C	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472400	n.555C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472494	n.649A>G	non_coding_transcript_exon_variant	0.76	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472498	n.653C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472513	n.668T>C	non_coding_transcript_exon_variant	0.67	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472518	n.673G>T	non_coding_transcript_exon_variant	0.26	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472544	n.699C>A	non_coding_transcript_exon_variant	0.3	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472545	n.700A>T	non_coding_transcript_exon_variant	0.3	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472549	n.704G>A	non_coding_transcript_exon_variant	0.63	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472566	n.721G>A	non_coding_transcript_exon_variant	0.32	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472571	n.726G>C	non_coding_transcript_exon_variant	0.33	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472581	n.736A>C	non_coding_transcript_exon_variant	0.63	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472581	n.736A>T	non_coding_transcript_exon_variant	0.37	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472584	n.739A>T	non_coding_transcript_exon_variant	0.61	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472598	n.753A>C	non_coding_transcript_exon_variant	0.35	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472599	n.754G>T	non_coding_transcript_exon_variant	0.35	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472647	n.802C>T	non_coding_transcript_exon_variant	0.41	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472655	n.810G>T	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472660	n.815T>C	non_coding_transcript_exon_variant	0.76	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472673	n.828_837delTTTCCTTCCTinsGGCCACCCG	non_coding_transcript_exon_variant	0.57	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472673	n.828_838delTTTCCTTCCTTinsGGGCCTTTTCC	non_coding_transcript_exon_variant	0.43	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472686	n.841_842delGAinsTT	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472690	n.845C>T	non_coding_transcript_exon_variant	0.57	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin
rrs	1472692	n.847T>C	non_coding_transcript_exon_variant	0.63	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472707	n.862A>T	non_coding_transcript_exon_variant	0.27	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472713	n.868T>C	non_coding_transcript_exon_variant	0.43	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472714	n.869A>G	non_coding_transcript_exon_variant	0.55	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472716	n.871C>T	non_coding_transcript_exon_variant	0.48	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472742	n.897C>T	non_coding_transcript_exon_variant	0.6	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472744	n.899A>G	non_coding_transcript_exon_variant	0.61	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472781	n.936C>T	non_coding_transcript_exon_variant	0.73	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472790	n.945T>C	non_coding_transcript_exon_variant	0.26	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472793	n.948A>T	non_coding_transcript_exon_variant	0.74	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472803	n.958T>A	non_coding_transcript_exon_variant	0.74	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472824	n.979T>A	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472825	n.980G>A	non_coding_transcript_exon_variant	0.48	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472827	n.982G>T	non_coding_transcript_exon_variant	0.39	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472828	n.983T>C	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472840	n.995A>G	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472880	n.1035G>A	non_coding_transcript_exon_variant	0.35	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472895	n.1050C>T	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472954	n.1109T>C	non_coding_transcript_exon_variant	0.37	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472956	n.1111T>C	non_coding_transcript_exon_variant	0.73	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472957	n.1112C>T	non_coding_transcript_exon_variant	0.47	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472958	n.1113A>G	non_coding_transcript_exon_variant	0.53	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472973	n.1128A>T	non_coding_transcript_exon_variant	0.79	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472974	n.1129A>G	non_coding_transcript_exon_variant	0.53	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472988	n.1143T>C	non_coding_transcript_exon_variant	0.55	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472990	n.1145A>G	non_coding_transcript_exon_variant	0.99	kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472992	n.1147A>G	non_coding_transcript_exon_variant	0.35	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473005	n.1160C>T	non_coding_transcript_exon_variant	0.34	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473035	n.1190G>A	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473055	n.1210C>T	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473056	n.1211A>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473066	n.1221A>G	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473088	n.1243A>G	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473093	n.1248C>T	non_coding_transcript_exon_variant	0.35	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473100	n.1255G>A	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473110	n.1265T>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473111	n.1266A>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473121	n.1276T>C	non_coding_transcript_exon_variant	0.96	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473123	n.1278A>T	non_coding_transcript_exon_variant	0.86	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473145	n.1300C>T	non_coding_transcript_exon_variant	0.45	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473148	n.1303G>T	non_coding_transcript_exon_variant	0.64	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473163	n.1318C>A	non_coding_transcript_exon_variant	0.64	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473166	n.1321G>A	non_coding_transcript_exon_variant	0.46	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473172	n.1327T>G	non_coding_transcript_exon_variant	0.33	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473173	n.1328C>T	non_coding_transcript_exon_variant	0.83	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1473221	n.1376C>T	non_coding_transcript_exon_variant	0.81	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473252	n.1407T>C	non_coding_transcript_exon_variant	0.68	kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473259	n.1414C>T	non_coding_transcript_exon_variant	0.69	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473262	n.1417T>C	non_coding_transcript_exon_variant	0.37	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473276	n.1431A>C	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473277	n.1432G>A	non_coding_transcript_exon_variant	0.49	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1473288	n.1443_1455delCTCGGGAGGGAGCinsGTTTTTGCGGGGGGAGT	non_coding_transcript_exon_variant	0.6	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473301	n.1456T>G	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473316	n.1471C>T	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1474171	n.514C>T	non_coding_transcript_exon_variant	0.54	capreomycin
rrl	1474171	n.514C>T	non_coding_transcript_exon_variant	0.54	linezolid
rrl	1474184	n.527C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474184	n.527C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	0.44	capreomycin	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	0.44	linezolid
rrl	1474197	n.540C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1474197	n.540C>T	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1474199	n.542G>C	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1474199	n.542G>C	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1474200	n.545delT	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474200	n.545delT	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1474454	n.797G>A	non_coding_transcript_exon_variant	0.63	capreomycin	Uncertain significance
rrl	1474454	n.797G>A	non_coding_transcript_exon_variant	0.63	linezolid	Uncertain significance
rrl	1474467	n.810A>G	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1474467	n.810A>G	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1474488	n.831G>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474488	n.831G>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474495	n.838G>A	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1474495	n.838G>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1474498	n.841G>T	non_coding_transcript_exon_variant	0.71	capreomycin
rrl	1474498	n.841G>T	non_coding_transcript_exon_variant	0.71	linezolid
rrl	1474505	n.848C>G	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1474505	n.848C>G	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1474508	n.851C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1474508	n.851C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1474516	n.859C>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474516	n.859C>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474527	n.870T>C	non_coding_transcript_exon_variant	0.73	capreomycin
rrl	1474527	n.870T>C	non_coding_transcript_exon_variant	0.73	linezolid
rrl	1474537	n.880G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474537	n.880G>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474542	n.885A>G	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1474542	n.885A>G	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.54	capreomycin	Uncertain significance
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.54	linezolid	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.39	capreomycin	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.39	linezolid	Uncertain significance
rrl	1474634	n.977T>C	non_coding_transcript_exon_variant	0.38	capreomycin
rrl	1474634	n.977T>C	non_coding_transcript_exon_variant	0.38	linezolid
rrl	1474634	n.977T>G	non_coding_transcript_exon_variant	0.34	capreomycin
rrl	1474634	n.977T>G	non_coding_transcript_exon_variant	0.34	linezolid
rrl	1474636	n.979A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474636	n.979A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.55	capreomycin	Uncertain significance
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474640	n.983C>T	non_coding_transcript_exon_variant	0.39	capreomycin	Uncertain significance
rrl	1474640	n.983C>T	non_coding_transcript_exon_variant	0.39	linezolid
rrl	1474658	n.1001A>G	non_coding_transcript_exon_variant	0.32	capreomycin
rrl	1474658	n.1001A>G	non_coding_transcript_exon_variant	0.32	linezolid
rrl	1474663	n.1006C>T	non_coding_transcript_exon_variant	0.59	capreomycin	Uncertain significance
rrl	1474663	n.1006C>T	non_coding_transcript_exon_variant	0.59	linezolid	Uncertain significance
rrl	1474673	n.1016_1019delTACTinsCACA	non_coding_transcript_exon_variant	0.44	capreomycin
rrl	1474673	n.1016_1019delTACTinsCACA	non_coding_transcript_exon_variant	0.44	linezolid
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474692	n.1035G>A	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1474692	n.1035G>A	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1474709	n.1052G>A	non_coding_transcript_exon_variant	0.43	capreomycin
rrl	1474709	n.1052G>A	non_coding_transcript_exon_variant	0.43	linezolid
rrl	1474711	n.1054_1060delGGTGTAAinsTAGGTGT	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474711	n.1054_1060delGGTGTAAinsTAGGTGT	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474734	n.1077G>C	non_coding_transcript_exon_variant	0.41	capreomycin
rrl	1474734	n.1077G>C	non_coding_transcript_exon_variant	0.41	linezolid
rrl	1474734	n.1077G>T	non_coding_transcript_exon_variant	0.59	capreomycin	Uncertain significance
rrl	1474734	n.1077G>T	non_coding_transcript_exon_variant	0.59	linezolid	Uncertain significance
rrl	1474749	n.1092C>T	non_coding_transcript_exon_variant	0.31	capreomycin	Uncertain significance
rrl	1474749	n.1092C>T	non_coding_transcript_exon_variant	0.31	linezolid	Uncertain significance
rrl	1474753	n.1096_1097delACinsG	non_coding_transcript_exon_variant	0.52	capreomycin
rrl	1474753	n.1096_1097delACinsG	non_coding_transcript_exon_variant	0.52	linezolid
rrl	1474753	n.1097delC	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1474753	n.1097delC	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474779	n.1122G>A	non_coding_transcript_exon_variant	0.28	capreomycin	Uncertain significance
rrl	1474779	n.1122G>A	non_coding_transcript_exon_variant	0.28	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474802	n.1145T>C	non_coding_transcript_exon_variant	0.25	capreomycin	Uncertain significance
rrl	1474802	n.1145T>C	non_coding_transcript_exon_variant	0.25	linezolid	Uncertain significance
rrl	1474824	n.1167A>G	non_coding_transcript_exon_variant	0.74	capreomycin	Uncertain significance
rrl	1474824	n.1167A>G	non_coding_transcript_exon_variant	0.74	linezolid	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474831	n.1174A>C	non_coding_transcript_exon_variant	0.52	capreomycin	Uncertain significance
rrl	1474831	n.1174A>C	non_coding_transcript_exon_variant	0.52	linezolid	Uncertain significance
rrl	1474831	n.1174A>T	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1474831	n.1174A>T	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1474832	n.1175A>T	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1474832	n.1175A>T	non_coding_transcript_exon_variant	0.58	linezolid	Uncertain significance
rrl	1474864	n.1207C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1474864	n.1207C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474903	n.1246T>C	non_coding_transcript_exon_variant	0.79	capreomycin	Uncertain significance
rrl	1474903	n.1246T>C	non_coding_transcript_exon_variant	0.79	linezolid	Uncertain significance
rrl	1474913	n.1256T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474913	n.1256T>C	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475090	n.1433A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475090	n.1433A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475104	n.1447T>A	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475104	n.1447T>A	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475114	n.1457C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475114	n.1457C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475124	n.1467A>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1475124	n.1467A>T	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1475171	n.1514C>T	non_coding_transcript_exon_variant	0.8	capreomycin	Uncertain significance
rrl	1475171	n.1514C>T	non_coding_transcript_exon_variant	0.8	linezolid	Uncertain significance
rrl	1475172	n.1515A>G	non_coding_transcript_exon_variant	0.64	capreomycin
rrl	1475172	n.1515A>G	non_coding_transcript_exon_variant	0.64	linezolid
rrl	1475175	n.1518G>C	non_coding_transcript_exon_variant	0.36	capreomycin	Uncertain significance
rrl	1475175	n.1518G>C	non_coding_transcript_exon_variant	0.36	linezolid	Uncertain significance
rrl	1475649	n.1992A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475649	n.1992A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475655	n.1998T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475655	n.1998T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475686	n.2029C>G	non_coding_transcript_exon_variant	0.52	capreomycin
rrl	1475686	n.2029C>G	non_coding_transcript_exon_variant	0.52	linezolid
rrl	1475696	n.2039T>C	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1475696	n.2039T>C	non_coding_transcript_exon_variant	0.87	linezolid	Uncertain significance
rrl	1475699	n.2042C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475699	n.2042C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475703	n.2046A>G	non_coding_transcript_exon_variant	0.88	capreomycin	Uncertain significance
rrl	1475703	n.2046A>G	non_coding_transcript_exon_variant	0.88	linezolid	Uncertain significance
rrl	1475715	n.2058G>C	non_coding_transcript_exon_variant	0.39	capreomycin
rrl	1475715	n.2058G>C	non_coding_transcript_exon_variant	0.39	linezolid
rrl	1475751	n.2094C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475751	n.2094C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475754	n.2097G>A	non_coding_transcript_exon_variant	0.4	capreomycin
rrl	1475754	n.2097G>A	non_coding_transcript_exon_variant	0.4	linezolid
rrl	1475756	n.2099_2108delTAACCCGCAAinsCAACCCTC	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475756	n.2099_2108delTAACCCGCAAinsCAACCCTC	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475774	n.2117C>T	non_coding_transcript_exon_variant	0.51	capreomycin
rrl	1475774	n.2117C>T	non_coding_transcript_exon_variant	0.51	linezolid
rrl	1475777	n.2120A>T	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1475777	n.2120A>T	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	0.45	capreomycin
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	0.45	linezolid
rrl	1475883	n.2226A>C	non_coding_transcript_exon_variant	0.62	capreomycin	Uncertain significance
rrl	1475883	n.2226A>C	non_coding_transcript_exon_variant	0.62	linezolid
rrl	1475883	n.2226A>T	non_coding_transcript_exon_variant	0.38	capreomycin	Uncertain significance
rrl	1475883	n.2226A>T	non_coding_transcript_exon_variant	0.38	linezolid	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.61	capreomycin	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.61	linezolid	Uncertain significance
rrl	1475898	n.2241A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475898	n.2241A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475899	n.2242G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475899	n.2242G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475900	n.2243A>G	non_coding_transcript_exon_variant	0.38	capreomycin	Uncertain significance
rrl	1475900	n.2243A>G	non_coding_transcript_exon_variant	0.38	linezolid
rrl	1475916	n.2259C>G	non_coding_transcript_exon_variant	0.64	capreomycin	Uncertain significance
rrl	1475916	n.2259C>G	non_coding_transcript_exon_variant	0.64	linezolid	Uncertain significance
rrl	1475916	n.2259C>T	non_coding_transcript_exon_variant	0.36	capreomycin	Uncertain significance
rrl	1475916	n.2259C>T	non_coding_transcript_exon_variant	0.36	linezolid	Uncertain significance
rrl	1475937	n.2280A>T	non_coding_transcript_exon_variant	0.62	capreomycin	Uncertain significance
rrl	1475937	n.2280A>T	non_coding_transcript_exon_variant	0.62	linezolid	Uncertain significance
rrl	1475943	n.2286G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475943	n.2286G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475945	n.2288C>A	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1475945	n.2288C>A	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1475952	n.2295A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475952	n.2295A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475970	n.2313C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475970	n.2313C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475975	n.2318C>T	non_coding_transcript_exon_variant	0.54	capreomycin	Uncertain significance
rrl	1475975	n.2318C>T	non_coding_transcript_exon_variant	0.54	linezolid	Uncertain significance
rrl	1475977	n.2320A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475977	n.2320A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1476164	n.2507A>G	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1476164	n.2507A>G	non_coding_transcript_exon_variant	0.58	linezolid	Uncertain significance
rrl	1476179	n.2522C>T	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1476179	n.2522C>T	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1476194	n.2537A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476194	n.2537A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476200	n.2543A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476200	n.2543A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476201	n.2544C>T	non_coding_transcript_exon_variant	0.44	capreomycin	Not assoc w R
rrl	1476201	n.2544C>T	non_coding_transcript_exon_variant	0.44	linezolid	Uncertain significance
rrl	1476204	n.2547C>T	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1476204	n.2547C>T	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1476207	n.2550T>C	non_coding_transcript_exon_variant	0.56	capreomycin
rrl	1476207	n.2550T>C	non_coding_transcript_exon_variant	0.56	linezolid
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.69	capreomycin	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.69	linezolid	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.7	capreomycin	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.7	linezolid	Uncertain significance
rrl	1476221	n.2564T>C	non_coding_transcript_exon_variant	0.64	capreomycin	Uncertain significance
rrl	1476221	n.2564T>C	non_coding_transcript_exon_variant	0.64	linezolid	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476245	n.2588C>T	non_coding_transcript_exon_variant	0.57	capreomycin	Uncertain significance
rrl	1476245	n.2588C>T	non_coding_transcript_exon_variant	0.57	linezolid	Uncertain significance
rrl	1476252	n.2595T>G	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1476252	n.2595T>G	non_coding_transcript_exon_variant	0.87	linezolid	Uncertain significance
rrl	1476256	n.2599A>G	non_coding_transcript_exon_variant	0.86	capreomycin	Uncertain significance
rrl	1476256	n.2599A>G	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1476311	n.2654G>C	non_coding_transcript_exon_variant	0.6	capreomycin	Uncertain significance
rrl	1476311	n.2654G>C	non_coding_transcript_exon_variant	0.6	linezolid	Uncertain significance
rrl	1476312	n.2655_2656delTGinsCA	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1476312	n.2655_2656delTGinsCA	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.78	capreomycin	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.78	linezolid	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.74	capreomycin	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.74	linezolid	Uncertain significance
rrl	1476353	n.2696G>T	non_coding_transcript_exon_variant	0.78	capreomycin	Uncertain significance
rrl	1476353	n.2696G>T	non_coding_transcript_exon_variant	0.78	linezolid	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1476369	n.2712C>T	non_coding_transcript_exon_variant	0.8	capreomycin	Uncertain significance
rrl	1476369	n.2712C>T	non_coding_transcript_exon_variant	0.8	linezolid	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.8	capreomycin	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.8	linezolid	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.84	linezolid	Uncertain significance
rrl	1476425	n.2768G>T	non_coding_transcript_exon_variant	0.78	capreomycin	Uncertain significance
rrl	1476425	n.2768G>T	non_coding_transcript_exon_variant	0.78	linezolid	Uncertain significance
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Not assoc w R
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1476429	n.2772A>C	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1476429	n.2772A>C	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.86	capreomycin	Not assoc w R
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	0.98	capreomycin	Not assoc w R
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476513	n.2856G>T	non_coding_transcript_exon_variant	0.35	capreomycin
rrl	1476513	n.2856G>T	non_coding_transcript_exon_variant	0.35	linezolid
rrl	1476514	n.2857C>T	non_coding_transcript_exon_variant	0.61	capreomycin	Uncertain significance
rrl	1476514	n.2857C>T	non_coding_transcript_exon_variant	0.61	linezolid	Uncertain significance
rrl	1476515	n.2858C>T	non_coding_transcript_exon_variant	0.4	capreomycin	Uncertain significance
rrl	1476515	n.2858C>T	non_coding_transcript_exon_variant	0.4	linezolid
rrl	1476519	n.2862C>G	non_coding_transcript_exon_variant	0.55	capreomycin	Uncertain significance
rrl	1476519	n.2862C>G	non_coding_transcript_exon_variant	0.55	linezolid	Uncertain significance
rrl	1476523	n.2866T>C	non_coding_transcript_exon_variant	0.36	capreomycin	Uncertain significance
rrl	1476523	n.2866T>C	non_coding_transcript_exon_variant	0.36	linezolid	Uncertain significance
rrl	1476524	n.2867C>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476524	n.2867C>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476525	n.2868A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476525	n.2868A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476528	n.2871A>G	non_coding_transcript_exon_variant	0.33	capreomycin	Uncertain significance
rrl	1476528	n.2871A>G	non_coding_transcript_exon_variant	0.33	linezolid
rrl	1476530	n.2873C>T	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1476530	n.2873C>T	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1476536	n.2879G>A	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1476536	n.2879G>A	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1476538	n.2881A>G	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1476538	n.2881A>G	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1476539	n.2882A>G	non_coding_transcript_exon_variant	0.88	capreomycin	Uncertain significance
rrl	1476539	n.2882A>G	non_coding_transcript_exon_variant	0.88	linezolid	Uncertain significance
rrl	1476540	n.2883C>G	non_coding_transcript_exon_variant	0.41	capreomycin	Uncertain significance
rrl	1476540	n.2883C>G	non_coding_transcript_exon_variant	0.41	linezolid	Uncertain significance
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.98	capreomycin	Not assoc w R
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476585	n.2928A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476585	n.2928A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476600	n.2943A>C	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1476600	n.2943A>C	non_coding_transcript_exon_variant	0.84	linezolid
rpsA	1834009	c.468C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834012	c.471G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834024	c.483G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834034	p.Ile165Val	missense_variant	1.0	pyrazinamide
rpsA	1834040	p.Lys167Arg	missense_variant	1.0	pyrazinamide
rpsA	1834046	p.Ile169Leu	missense_variant	1.0	pyrazinamide
rpsA	1834054	c.513C>G	synonymous_variant	0.95	pyrazinamide
rpsA	1834093	c.552G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834096	c.555G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834102	c.561T>C	synonymous_variant	0.93	pyrazinamide
rpsA	1834114	c.573G>C	synonymous_variant	0.8	pyrazinamide

Drug	Resistance	Supporting mutations	WHO confidence	Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin	rrs	n.888G>A	Uncertain significance	Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid

TB-Profiler result