TB-Profiler result

Run: ERR553132
Summary

Run ID: ERR553132

Sample name:

Date: 15-08-2022 11:00:22

Number of reads: 1572604

Percentage reads mapped: 87.67

Strain: lineage4.1.2.1

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
La1.2.BCG M.bovis BCG None 0.05
lineage4.1 Euro-American T;X;H None 0.96
lineage4.1.2 Euro-American T;H None 0.97
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761161 p.Leu452Pro missense_variant 0.83 rifampicin
rpsL 781822 p.Lys88Arg missense_variant 0.83 streptomycin
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.15 streptomycin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247580 p.Ala356Val missense_variant 0.14 ethambutol
embB 4247588 p.Leu359Ile missense_variant 0.15 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6982 c.-320A>C upstream_gene_variant 0.18
gyrA 7007 c.-295C>T upstream_gene_variant 0.19
gyrA 7010 c.-292C>T upstream_gene_variant 0.19
gyrB 7023 p.Leu595Gln missense_variant 0.19
gyrA 7033 c.-269G>C upstream_gene_variant 0.19
gyrB 7051 p.Glu604Asp missense_variant 0.19
gyrA 7066 c.-236G>C upstream_gene_variant 0.19
gyrA 7078 c.-224A>C upstream_gene_variant 0.17
gyrA 7084 c.-218A>G upstream_gene_variant 0.18
gyrA 7090 c.-212C>T upstream_gene_variant 0.16
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7480 p.Phe60Tyr missense_variant 0.15
gyrA 7484 c.183T>C synonymous_variant 0.16
gyrA 7514 c.213C>G synonymous_variant 0.17
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8636 c.1335A>C synonymous_variant 0.15
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 0.95
mshA 575679 p.Asn111Ser missense_variant 0.96
rpoB 760106 c.300G>A synonymous_variant 0.92
rpoB 760115 c.309C>T synonymous_variant 0.92
rpoB 760340 c.534G>T synonymous_variant 0.16
rpoB 760361 c.555T>C synonymous_variant 0.15
rpoB 760381 p.Thr192Met missense_variant 0.14
rpoB 760406 c.600G>C synonymous_variant 0.17
rpoB 760424 c.618C>G synonymous_variant 0.16
rpoB 760430 c.624T>C synonymous_variant 0.16
rpoB 760481 c.675G>C synonymous_variant 0.16
rpoB 760591 p.Val262Ala missense_variant 0.15
rpoB 761057 c.1251G>C synonymous_variant 0.15
rpoB 761102 c.1296A>G synonymous_variant 0.15
rpoB 761129 c.1323G>C synonymous_variant 0.17
rpoB 761132 c.1326G>T synonymous_variant 0.17
rpoB 761133 c.1327T>C synonymous_variant 0.17
rpoB 761150 c.1344A>C synonymous_variant 0.17
rpoB 761153 c.1347G>C synonymous_variant 0.18
rpoB 761165 c.1359G>C synonymous_variant 0.19
rpoB 761180 c.1374A>C synonymous_variant 0.17
rpoB 761189 c.1383T>C synonymous_variant 0.17
rpoB 761195 c.1389G>C synonymous_variant 0.18
rpoB 761207 c.1401C>T synonymous_variant 0.18
rpoB 761213 c.1407G>C synonymous_variant 0.17
rpoB 761219 c.1413G>C synonymous_variant 0.16
rpoB 761249 c.1443A>G synonymous_variant 0.16
rpoC 762989 c.-381G>C upstream_gene_variant 0.2
rpoC 762995 c.-375G>T upstream_gene_variant 0.21
rpoC 763013 c.-357C>G upstream_gene_variant 0.21
rpoC 763028 c.-342T>C upstream_gene_variant 0.22
rpoC 763031 c.-339T>G upstream_gene_variant 0.21
rpoC 763034 c.-336C>G upstream_gene_variant 0.21
rpoC 763040 c.-330C>G upstream_gene_variant 0.23
rpoC 763070 c.-300T>C upstream_gene_variant 0.23
rpoC 763085 c.-285C>G upstream_gene_variant 0.25
rpoC 763115 c.-255T>C upstream_gene_variant 0.24
rpoC 763136 c.-234C>T upstream_gene_variant 0.23
rpoC 763148 c.-222G>C upstream_gene_variant 0.21
rpoC 763158 c.-212C>T upstream_gene_variant 0.19
rpoC 763166 c.-204A>G upstream_gene_variant 0.19
rpoC 763190 c.-180C>T upstream_gene_variant 0.15
rpoC 764489 c.1120C>T synonymous_variant 0.16
rpoC 764497 c.1128A>G synonymous_variant 0.15
rpoC 764510 c.1141C>T synonymous_variant 0.15
rpoC 764521 c.1152T>C synonymous_variant 0.16
rpoC 764527 c.1158C>T synonymous_variant 0.16
rpoC 764536 c.1167G>C synonymous_variant 0.16
rpoC 764554 c.1185C>T synonymous_variant 0.2
rpoC 764560 c.1191T>C synonymous_variant 0.19
rpoC 764566 c.1197C>G synonymous_variant 0.19
rpoC 764575 c.1206T>G synonymous_variant 0.23
rpoC 764581 c.1212T>C synonymous_variant 0.22
rpoC 764593 c.1224C>T synonymous_variant 0.22
rpoC 764611 c.1242G>T synonymous_variant 0.22
rpoC 764650 c.1281G>C synonymous_variant 0.23
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.23
rpoC 764752 c.1383G>C synonymous_variant 0.17
rpoC 764764 c.1395T>C synonymous_variant 0.16
rpoC 764809 c.1440C>T synonymous_variant 0.15
rpoC 764815 c.1446A>G synonymous_variant 0.16
rpoC 765150 p.Gly594Glu missense_variant 0.99
rpoC 765319 c.1950A>G synonymous_variant 0.15
rpoC 765326 p.His653Ala missense_variant 0.15
rpoC 765329 p.Ser654Gly missense_variant 0.15
rpoC 765346 c.1977C>G synonymous_variant 0.16
rpoC 765349 c.1980T>C synonymous_variant 0.16
rpoC 765352 c.1983G>C synonymous_variant 0.18
rpoC 765383 p.Met672Leu missense_variant 0.2
rpoC 765404 p.Leu679Val missense_variant 0.23
rpoC 765409 c.2040T>C synonymous_variant 0.22
rpoC 765421 c.2052C>G synonymous_variant 0.2
rpoC 765478 c.2109T>C synonymous_variant 0.21
rpoC 765499 c.2130C>G synonymous_variant 0.21
rpoC 765529 c.2160C>T synonymous_variant 0.22
rpoC 765541 c.2172C>G synonymous_variant 0.24
rpoC 765553 c.2184C>T synonymous_variant 0.22
rpoC 765556 c.2187G>C synonymous_variant 0.21
rpoC 765559 c.2190G>C synonymous_variant 0.21
rpoC 765580 c.2211G>C synonymous_variant 0.21
rpoC 765613 p.His748Gln missense_variant 0.18
rpoC 765625 c.2256C>G synonymous_variant 0.19
rpoC 765631 p.Asp754Glu missense_variant 0.18
rpoC 765700 c.2331T>C synonymous_variant 0.17
rpoC 765734 c.2365T>C synonymous_variant 0.17
rpoC 765739 c.2370G>T synonymous_variant 0.17
rpoC 765751 c.2382C>G synonymous_variant 0.16
rpoC 765753 p.Asp795Ala missense_variant 0.16
rpoC 765772 c.2403C>G synonymous_variant 0.15
rpoC 765787 c.2418C>T synonymous_variant 0.13
rpoC 765793 c.2424C>G synonymous_variant 0.14
rpoC 765796 c.2427C>T synonymous_variant 0.14
rpoC 765811 c.2442T>C synonymous_variant 0.14
rpoC 765814 c.2445A>G synonymous_variant 0.15
rpoC 765826 c.2457T>C synonymous_variant 0.14
rpoC 765835 c.2466C>T synonymous_variant 0.15
rpoC 765937 c.2568T>C synonymous_variant 0.15
rpoC 765967 c.2598C>T synonymous_variant 0.15
rpoC 766096 c.2727G>C synonymous_variant 0.15
rpoC 766738 c.3369G>C synonymous_variant 0.15
rpoC 766747 c.3378C>T synonymous_variant 0.13
rpoC 766861 c.3492G>C synonymous_variant 0.24
rpoC 766864 c.3495G>C synonymous_variant 0.25
rpoC 766867 c.3498C>G synonymous_variant 0.24
rpoC 766882 c.3513C>T synonymous_variant 0.23
rpoC 766894 c.3525T>C synonymous_variant 0.21
rpoC 766900 c.3531T>C synonymous_variant 0.22
rpoC 766933 c.3564A>G synonymous_variant 0.19
rpoC 766945 c.3576A>G synonymous_variant 0.19
rpoC 766963 c.3594T>C synonymous_variant 0.21
rpoC 766972 c.3603G>C synonymous_variant 0.2
rpoC 766987 c.3618G>C synonymous_variant 0.18
rpoC 766996 c.3627C>T synonymous_variant 0.18
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.18
rpoC 767014 c.3645G>C synonymous_variant 0.18
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.2
rpoC 767059 c.3690T>G synonymous_variant 0.16
rpoC 767062 c.3693C>A synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781742 c.183C>T synonymous_variant 0.14
rpsL 781748 c.189C>G synonymous_variant 0.15
rpsL 781760 c.201T>C synonymous_variant 0.15
rpsL 781772 c.213C>A synonymous_variant 0.16
rpsL 781808 c.249C>T synonymous_variant 0.17
rpsL 781811 c.252C>T synonymous_variant 0.17
rpsL 781832 c.273T>C synonymous_variant 0.16
rpsL 781838 c.279G>C synonymous_variant 0.16
rpsL 781841 c.282C>G synonymous_variant 0.16
rpsL 781865 c.306G>C synonymous_variant 0.17
rpsL 781868 c.309T>C synonymous_variant 0.17
rpsL 781871 c.312G>C synonymous_variant 0.19
rpsL 781877 c.318T>C synonymous_variant 0.2
rpsL 781892 c.333A>G synonymous_variant 0.19
rpsL 781898 c.339A>T synonymous_variant 0.19
rpsL 781916 c.357T>C synonymous_variant 0.19
rpsL 781929 p.Gly124Ser missense_variant 0.19
rplC 801207 c.399C>T synonymous_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.13
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.13
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.14
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.14
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 0.15
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.15
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.15
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.15
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.14
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.17
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.15
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.16
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.18
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.24
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.24
rrl 1473938 n.281G>A non_coding_transcript_exon_variant 0.22
rrl 1473939 n.282C>T non_coding_transcript_exon_variant 0.23
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.25
rrl 1473981 n.324G>T non_coding_transcript_exon_variant 0.22
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.23
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.23
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.24
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.25
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.25
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.25
rrl 1474044 n.387C>T non_coding_transcript_exon_variant 0.22
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.19
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.19
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.2
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.19
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.19
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.23
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.24
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.2
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.17
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.13
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.22
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.22
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.23
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.25
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.3
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.31
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.32
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.32
rrl 1474964 n.1307T>C non_coding_transcript_exon_variant 0.32
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.33
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.36
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.28
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.23
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.26
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.2
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.2
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.2
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.2
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.21
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.2
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.24
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.22
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.23
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.23
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.26
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.23
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.21
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.21
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.18
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.15
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.19
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.21
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.19
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.18
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.16
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.18
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.21
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.2
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.2
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.18
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.21
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.22
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.22
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.24
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.23
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.23
inhA 1673685 c.-517C>T upstream_gene_variant 0.16
fabG1 1673710 p.Leu91Ile missense_variant 0.16
inhA 1674759 c.558G>C synonymous_variant 0.15
rpsA 1833724 c.183C>G synonymous_variant 0.14
rpsA 1833727 c.186G>C synonymous_variant 0.14
rpsA 1834210 c.669C>T synonymous_variant 0.14
rpsA 1834249 c.708T>C synonymous_variant 0.14
rpsA 1834333 c.792C>T synonymous_variant 0.14
rpsA 1834348 c.807T>C synonymous_variant 0.14
rpsA 1834417 c.876G>C synonymous_variant 0.15
rpsA 1834435 c.894G>C synonymous_variant 0.15
rpsA 1834489 c.948T>C synonymous_variant 0.15
rpsA 1834513 c.972C>G synonymous_variant 0.16
rpsA 1834528 c.987T>C synonymous_variant 0.15
rpsA 1834540 c.999G>C synonymous_variant 0.17
rpsA 1834546 c.1005T>C synonymous_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
kasA 2518768 c.654C>T synonymous_variant 0.15
kasA 2518777 c.663C>T synonymous_variant 0.15
kasA 2518792 c.678C>A synonymous_variant 0.14
Rv2752c 3065048 c.1144C>T synonymous_variant 0.14
thyX 3067531 p.Ala139Thr missense_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3877692 c.816G>C synonymous_variant 0.15
rpoA 3877737 c.771G>C synonymous_variant 0.16
rpoA 3877743 c.765T>C synonymous_variant 0.17
rpoA 3877764 c.744C>G synonymous_variant 0.2
rpoA 3877770 c.738A>G synonymous_variant 0.19
rpoA 3877776 c.732T>C synonymous_variant 0.2
rpoA 3877782 c.726T>C synonymous_variant 0.21
rpoA 3877791 c.717C>G synonymous_variant 0.22
rpoA 3877818 c.690A>G synonymous_variant 0.2
rpoA 3877839 c.669G>C synonymous_variant 0.2
rpoA 3877857 c.651G>A synonymous_variant 0.17
rpoA 3877866 c.642G>C synonymous_variant 0.17
rpoA 3877875 c.633T>G synonymous_variant 0.18
rpoA 3877878 c.630G>C synonymous_variant 0.18
rpoA 3877890 c.618C>T synonymous_variant 0.17
rpoA 3877896 c.612G>C synonymous_variant 0.18
rpoA 3877900 p.Ser203Asn missense_variant 0.17
rpoA 3877905 c.603A>G synonymous_variant 0.16
rpoA 3877908 p.Asn200Ser missense_variant 0.16
rpoA 3877920 c.588G>C synonymous_variant 0.18
rpoA 3877926 c.582G>C synonymous_variant 0.19
rpoA 3877962 c.546G>C synonymous_variant 0.21
rpoA 3877986 c.522G>C synonymous_variant 0.23
rpoA 3877989 c.519A>G synonymous_variant 0.23
rpoA 3878001 c.507A>G synonymous_variant 0.22
rpoA 3878022 c.486T>C synonymous_variant 0.22
rpoA 3878028 c.480G>C synonymous_variant 0.18
rpoA 3878031 c.477T>C synonymous_variant 0.19
rpoA 3878040 c.468T>C synonymous_variant 0.19
rpoA 3878046 c.462T>C synonymous_variant 0.19
rpoA 3878055 c.453A>G synonymous_variant 0.19
rpoA 3878058 c.450G>T synonymous_variant 0.18
rpoA 3878061 c.447G>C synonymous_variant 0.18
rpoA 3878067 c.441C>G synonymous_variant 0.19
rpoA 3878070 c.438T>C synonymous_variant 0.19
rpoA 3878076 c.432C>T synonymous_variant 0.2
rpoA 3878094 c.414C>G synonymous_variant 0.18
rpoA 3878103 c.405A>G synonymous_variant 0.17
rpoA 3878106 c.402G>C synonymous_variant 0.17
rpoA 3878118 c.390T>C synonymous_variant 0.16
rpoA 3878130 c.378C>G synonymous_variant 0.15
rpoA 3878143 p.Gly122Asp missense_variant 0.14
rpoA 3878271 c.237T>C synonymous_variant 0.16
rpoA 3878284 p.Glu75Ala missense_variant 0.16
rpoA 3878292 c.216T>C synonymous_variant 0.15
rpoA 3878310 c.198G>C synonymous_variant 0.15
rpoA 3878322 c.186A>G synonymous_variant 0.15
rpoA 3878331 c.177A>G synonymous_variant 0.14
rpoA 3878334 c.174T>C synonymous_variant 0.15
rpoA 3878337 c.171T>C synonymous_variant 0.15
rpoA 3878346 c.162T>C synonymous_variant 0.16
rpoA 3878364 c.144A>C synonymous_variant 0.16
rpoA 3878367 c.141C>G synonymous_variant 0.16
rpoA 3878376 c.132G>C synonymous_variant 0.16
rpoA 3878385 c.123C>G synonymous_variant 0.15
rpoA 3878388 c.120C>G synonymous_variant 0.16
rpoA 3878391 c.117T>C synonymous_variant 0.16
rpoA 3878424 c.84G>C synonymous_variant 0.16
rpoA 3878436 c.72A>G synonymous_variant 0.16
rpoA 3878442 c.66G>C synonymous_variant 0.17
rpoA 3878454 c.54A>C synonymous_variant 0.19
rpoA 3878463 c.45C>A synonymous_variant 0.14
rpoA 3878484 c.24C>A synonymous_variant 0.14
rpoA 3878496 c.12A>T synonymous_variant 0.14
clpC1 4038596 c.2109A>G synonymous_variant 0.16
clpC1 4038623 c.2082A>G synonymous_variant 0.16
clpC1 4038640 p.Asp689Asn missense_variant 0.16
clpC1 4038653 c.2052C>T synonymous_variant 0.16
clpC1 4038658 p.Lys683Gln missense_variant 0.16
clpC1 4038661 p.Ser682Thr missense_variant 0.17
clpC1 4038662 c.2043T>C synonymous_variant 0.17
clpC1 4038671 c.2034T>C synonymous_variant 0.18
clpC1 4038683 c.2022T>C synonymous_variant 0.17
clpC1 4038695 c.2010C>G synonymous_variant 0.17
clpC1 4038701 c.2004G>C synonymous_variant 0.16
clpC1 4038704 c.2001T>C synonymous_variant 0.15
clpC1 4038707 c.1998C>G synonymous_variant 0.16
clpC1 4038710 c.1995G>C synonymous_variant 0.16
clpC1 4038713 c.1992T>C synonymous_variant 0.16
clpC1 4038749 c.1956C>A synonymous_variant 0.19
clpC1 4038755 c.1950G>T synonymous_variant 0.18
clpC1 4038770 c.1935C>T synonymous_variant 0.18
clpC1 4038773 c.1932T>C synonymous_variant 0.18
clpC1 4038782 c.1923G>C synonymous_variant 0.18
clpC1 4038812 c.1893T>C synonymous_variant 0.18
clpC1 4038845 c.1860G>C synonymous_variant 0.19
clpC1 4038860 c.1845G>C synonymous_variant 0.19
clpC1 4038878 c.1827A>G synonymous_variant 0.21
clpC1 4038893 c.1812C>T synonymous_variant 0.22
clpC1 4038908 c.1797C>G synonymous_variant 0.24
clpC1 4038914 c.1791G>C synonymous_variant 0.23
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.21
clpC1 4038953 c.1752A>G synonymous_variant 0.21
clpC1 4038956 c.1749T>C synonymous_variant 0.2
clpC1 4038965 c.1740T>C synonymous_variant 0.21
clpC1 4038971 c.1734T>C synonymous_variant 0.19
clpC1 4038974 c.1731T>C synonymous_variant 0.19
clpC1 4038989 c.1716T>C synonymous_variant 0.19
clpC1 4038997 c.1708T>C synonymous_variant 0.19
clpC1 4039004 c.1701C>G synonymous_variant 0.18
clpC1 4039022 c.1683A>G synonymous_variant 0.16
clpC1 4039064 c.1641C>T synonymous_variant 0.16
clpC1 4039106 c.1599G>C synonymous_variant 0.15
clpC1 4039145 c.1560G>C synonymous_variant 0.15
clpC1 4039178 c.1527G>C synonymous_variant 0.14
clpC1 4039183 c.1522T>C synonymous_variant 0.16
clpC1 4039186 c.1519C>T synonymous_variant 0.16
clpC1 4039190 c.1515C>G synonymous_variant 0.16
clpC1 4039274 c.1431G>C synonymous_variant 0.15
clpC1 4039850 c.855T>C synonymous_variant 0.17
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.15
clpC1 4039937 c.768G>C synonymous_variant 0.15
clpC1 4039946 c.759A>C synonymous_variant 0.17
clpC1 4039952 c.753T>C synonymous_variant 0.17
clpC1 4039982 c.723G>A synonymous_variant 0.17
clpC1 4039988 c.717C>G synonymous_variant 0.17
clpC1 4039991 c.714G>C synonymous_variant 0.17
clpC1 4040021 c.684A>C synonymous_variant 0.17
clpC1 4040024 c.681A>G synonymous_variant 0.17
clpC1 4040033 c.672G>C synonymous_variant 0.18
clpC1 4040036 c.669C>G synonymous_variant 0.18
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.18
clpC1 4040093 c.612C>G synonymous_variant 0.18
clpC1 4040105 c.600C>G synonymous_variant 0.17
clpC1 4040147 c.558A>G synonymous_variant 0.16
clpC1 4040162 c.543G>C synonymous_variant 0.17
clpC1 4040165 c.540G>C synonymous_variant 0.16
clpC1 4040171 c.534C>G synonymous_variant 0.17
clpC1 4040201 c.504C>G synonymous_variant 0.15
clpC1 4040215 p.Ser164Thr missense_variant 0.14
clpC1 4040237 c.468C>T synonymous_variant 0.15
clpC1 4040246 c.459C>G synonymous_variant 0.19
clpC1 4040249 c.456A>G synonymous_variant 0.18
clpC1 4040267 c.438A>G synonymous_variant 0.17
clpC1 4040273 c.432T>C synonymous_variant 0.17
clpC1 4040276 c.427_429delTCCinsAGT synonymous_variant 0.17
clpC1 4040279 c.426C>G synonymous_variant 0.17
clpC1 4040291 c.414G>C synonymous_variant 0.17
clpC1 4040318 c.387C>G synonymous_variant 0.15
embC 4240660 c.798C>G synonymous_variant 0.15
embC 4240669 c.807G>C synonymous_variant 0.15
embC 4240671 p.Thr270Ile missense_variant 0.15
embC 4240693 c.831T>G synonymous_variant 0.15
embC 4240699 c.837C>G synonymous_variant 0.15
embC 4240726 c.864G>C synonymous_variant 0.16
embC 4241551 c.1689A>G synonymous_variant 0.15
embC 4241567 p.Ile569Val missense_variant 0.18
embC 4241572 c.1710C>G synonymous_variant 0.17
embC 4241578 c.1716G>C synonymous_variant 0.17
embC 4241584 c.1722T>C synonymous_variant 0.2
embC 4241587 c.1725C>G synonymous_variant 0.2
embC 4241591 p.Leu577Val missense_variant 0.17
embC 4241611 c.1749G>C synonymous_variant 0.18
embC 4241614 c.1752A>C synonymous_variant 0.18
embC 4241626 c.1764T>C synonymous_variant 0.18
embC 4241635 c.1773G>C synonymous_variant 0.16
embC 4241644 c.1782G>C synonymous_variant 0.16
embC 4241648 c.1786_1788delTTGinsCTC synonymous_variant 0.16
embC 4241657 p.Ser599Pro missense_variant 0.16
embC 4241665 c.1803G>C synonymous_variant 0.17
embC 4241671 c.1809T>C synonymous_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 0.95
embC 4242803 p.Val981Leu missense_variant 0.97
embB 4247566 c.1053C>A synonymous_variant 0.14
embB 4247587 c.1074G>A synonymous_variant 0.15
embB 4247603 c.1090C>T synonymous_variant 0.17
embB 4247611 c.1098G>T synonymous_variant 0.17
embB 4247614 c.1101T>C synonymous_variant 0.17
embB 4247629 c.1116C>G synonymous_variant 0.14
embB 4247632 c.1119C>G synonymous_variant 0.14
embB 4247887 c.1374C>T synonymous_variant 0.15
embB 4247893 c.1380C>T synonymous_variant 0.15
embB 4247899 p.Met462Ile missense_variant 0.15
embB 4247905 c.1392G>C synonymous_variant 0.15
embB 4247909 c.1396T>C synonymous_variant 0.15
embB 4247914 c.1401G>C synonymous_variant 0.15
embB 4248172 c.1659G>C synonymous_variant 0.15
embB 4249568 p.Ser1019Thr missense_variant 0.14
embB 4249580 p.Leu1023Met missense_variant 0.14
embB 4249606 c.3093C>A synonymous_variant 0.14
embB 4249624 c.3111C>G synonymous_variant 0.14
embB 4249657 c.3144C>G synonymous_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0