TB-Profiler result

Run: ERR4822261
Summary

Run ID: ERR4822261

Sample name:

Date: 01-04-2023 17:43:50

Number of reads: 1185782

Percentage reads mapped: 55.5

Strain: lineage2.2.1

Drug-resistance: RR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761110 p.Asp435Val missense_variant 0.12 rifampicin
rpoB 761127 p.Ser441Ala missense_variant 0.25 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.7 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoB 761039 p.Leu411Phe missense_variant 0.19
rpoB 761054 c.1248G>C synonymous_variant 0.12
rpoB 761058 p.Val418Thr missense_variant 0.31
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.26
rpoB 761096 c.1290G>C synonymous_variant 0.23
rpoB 761102 c.1296A>G synonymous_variant 0.23
rpoB 761132 c.1326G>C synonymous_variant 0.24
rpoB 761133 c.1327T>C synonymous_variant 0.22
rpoB 761612 c.1806G>C synonymous_variant 0.19
rpoB 761615 c.1809A>C synonymous_variant 0.2
rpoB 761633 c.1827G>C synonymous_variant 0.2
rpoB 761990 c.2184G>C synonymous_variant 0.18
rpoB 761997 p.Leu731Ile missense_variant 0.18
rpoB 762003 p.Asn733Gln missense_variant 0.21
rpoB 762009 p.Leu735Val missense_variant 0.23
rpoB 762016 p.Glu737Ala missense_variant 0.23
rpoB 762024 p.Val740Met missense_variant 0.33
rpoB 762053 c.2247T>C synonymous_variant 0.31
rpoB 762057 p.Ile751Val missense_variant 0.28
rpoB 762062 c.2256T>C synonymous_variant 0.28
rpoB 762065 c.2259T>C synonymous_variant 0.26
rpoB 762083 c.2277T>A synonymous_variant 0.12
rpoB 762086 c.2280G>C synonymous_variant 0.12
rpoB 762110 c.2304G>C synonymous_variant 0.11
rpoC 762926 c.-444C>G upstream_gene_variant 0.17
rpoC 762929 c.-441G>T upstream_gene_variant 0.17
rpoC 762938 c.-432G>C upstream_gene_variant 0.17
rpoC 762944 c.-426C>T upstream_gene_variant 0.16
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.22
rpoC 763043 c.-327G>C upstream_gene_variant 0.24
rpoC 763053 c.-317T>C upstream_gene_variant 0.28
rpoC 763067 c.-303C>G upstream_gene_variant 0.17
rpoC 763070 c.-300T>C upstream_gene_variant 0.19
rpoB 763077 p.Val1091Thr missense_variant 0.23
rpoC 763103 c.-267G>C upstream_gene_variant 0.21
rpoC 763109 c.-261C>T upstream_gene_variant 0.16
rpoC 763115 c.-255T>C upstream_gene_variant 0.19
rpoB 763119 p.Asn1105Asp missense_variant 0.18
rpoC 763127 c.-243G>C upstream_gene_variant 0.12
rpoC 763468 c.99G>C synonymous_variant 0.14
rpoC 763483 c.114G>C synonymous_variant 0.12
rpoC 763486 c.117T>C synonymous_variant 0.11
rpoC 763492 c.123G>C synonymous_variant 0.17
rpoC 763507 c.138G>C synonymous_variant 0.23
rpoC 763528 c.159G>C synonymous_variant 0.27
rpoC 763531 c.162G>C synonymous_variant 0.28
rpoC 763534 c.165T>C synonymous_variant 0.28
rpoC 763537 c.168C>G synonymous_variant 0.25
rpoC 763546 c.177A>G synonymous_variant 0.29
rpoC 763550 p.Tyr61Ala missense_variant 0.29
rpoC 763558 c.189C>T synonymous_variant 0.15
rpoC 763570 c.201G>C synonymous_variant 0.32
rpoC 763578 p.Phe70Tyr missense_variant 0.4
rpoC 763585 c.216C>G synonymous_variant 0.4
rpoC 763589 p.Ile74Val missense_variant 0.35
rpoC 763597 c.228G>A synonymous_variant 0.23
rpoC 763606 c.237C>A synonymous_variant 0.35
rpoC 763615 c.246G>C synonymous_variant 0.38
rpoC 763618 c.249C>T synonymous_variant 0.36
rpoC 763622 p.Ala85Ser missense_variant 0.35
rpoC 763642 c.273G>C synonymous_variant 0.36
rpoC 763647 p.Gly93Ala missense_variant 0.34
rpoC 763655 p.Glu96Lys missense_variant 0.38
rpoC 763660 c.291T>C synonymous_variant 0.38
rpoC 763669 c.300C>G synonymous_variant 0.32
rpoC 763696 c.327T>C synonymous_variant 0.17
rpoC 763699 c.330G>T synonymous_variant 0.2
rpoC 763708 c.339G>C synonymous_variant 0.32
rpoC 763714 c.345G>C synonymous_variant 0.31
rpoC 763717 c.348T>C synonymous_variant 0.29
rpoC 763723 c.354G>C synonymous_variant 0.28
rpoC 763724 p.Asp119Asn missense_variant 0.28
rpoC 763729 c.360G>C synonymous_variant 0.23
rpoC 763732 c.363C>G synonymous_variant 0.2
rpoC 763735 c.366G>C synonymous_variant 0.3
rpoC 763751 p.Ile128Val missense_variant 0.24
rpoC 764509 c.1140G>C synonymous_variant 0.11
rpoC 764521 c.1152T>C synonymous_variant 0.16
rpoC 764536 c.1167G>C synonymous_variant 0.19
rpoC 764539 c.1170C>G synonymous_variant 0.13
rpoC 764548 c.1179G>C synonymous_variant 0.12
rpoC 764549 p.Pro394Val missense_variant 0.15
rpoC 764566 c.1197C>G synonymous_variant 0.16
rpoC 764572 c.1203G>C synonymous_variant 0.14
rpoC 764575 c.1206T>G synonymous_variant 0.14
rpoC 764581 c.1212T>C synonymous_variant 0.19
rpoC 764582 p.Leu405Met missense_variant 0.18
rpoC 764605 c.1236G>C synonymous_variant 0.16
rpoC 764611 c.1242G>C synonymous_variant 0.14
rpoC 764632 c.1263T>C synonymous_variant 0.18
rpoC 764650 c.1281G>T synonymous_variant 0.13
rpoC 764653 c.1284G>C synonymous_variant 0.17
rpoC 764662 c.1293G>C synonymous_variant 0.17
rpoC 765923 p.Asn852Ala missense_variant 0.12
rpoC 765934 c.2565C>T synonymous_variant 0.14
rpoC 765937 c.2568T>C synonymous_variant 0.17
rpoC 765940 c.2571A>T synonymous_variant 0.17
rpoC 765947 c.2578T>C synonymous_variant 0.19
rpoC 765958 c.2589C>G synonymous_variant 0.21
rpoC 765962 c.2593T>C synonymous_variant 0.2
rpoC 765967 c.2598C>T synonymous_variant 0.28
rpoC 765988 c.2619G>C synonymous_variant 0.21
rpoC 765991 c.2622C>G synonymous_variant 0.22
rpoC 765994 c.2625A>T synonymous_variant 0.22
rpoC 766003 c.2634G>C synonymous_variant 0.19
rpoC 766009 c.2640G>C synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 778527 p.Thr127Ala missense_variant 0.12
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781623 p.Ala22Pro missense_variant 0.12
rpsL 781628 c.69T>G synonymous_variant 0.12
rpsL 781639 p.Ser27Thr missense_variant 0.13
rpsL 781643 c.84G>C synonymous_variant 0.12
rpsL 781652 c.93T>C synonymous_variant 0.12
rpsL 781655 c.96T>C synonymous_variant 0.12
rpsL 781658 c.99A>G synonymous_variant 0.12
rpsL 781682 c.123T>G synonymous_variant 0.14
rpsL 781706 c.147T>G synonymous_variant 0.11
rpsL 781709 c.150G>A synonymous_variant 0.11
rpsL 781908 p.Tyr117His missense_variant 0.11
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.5
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.82
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.86
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.96
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.52
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.83
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.87
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.94
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.9
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.89
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.44
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.93
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.48
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.42
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.43
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.92
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.87
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.92
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.75
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.75
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.8
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.67
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.71
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.71
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.67
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.67
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.67
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.67
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.75
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.75
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.26
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.68
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.68
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.79
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.8
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.82
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.82
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.17
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.79
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.81
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.49
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.73
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.22
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.21
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.76
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.76
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.37
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.2
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.88
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.9
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.41
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.55
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.4
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.36
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 0.86
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.53
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.28
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.67
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.14
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.61
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.36
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.62
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.68
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.68
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.67
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.32
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.65
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.66
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.91
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.4
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.42
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.92
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 0.5
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.9
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.39
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.92
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.42
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.51
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.93
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.94
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.49
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.52
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.98
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.37
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.36
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.96
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.93
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.94
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.95
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.22
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.36
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.93
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.3
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.92
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.21
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.91
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.91
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.91
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.81
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.92
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.37
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.47
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.55
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.55
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.49
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.4
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.9
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.86
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.53
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.53
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.38
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.89
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.59
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.27
rrs 1473284 n.1439A>T non_coding_transcript_exon_variant 0.27
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.5
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.8
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.3
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.3
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.8
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.37
rrl 1473782 n.125A>G non_coding_transcript_exon_variant 0.57
rrl 1473783 n.126A>G non_coding_transcript_exon_variant 0.57
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.67
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.86
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.86
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.86
rrl 1473811 n.154C>T non_coding_transcript_exon_variant 0.86
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.86
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.86
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.86
rrl 1473840 n.183A>G non_coding_transcript_exon_variant 0.86
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 1.0
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.9
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.94
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.53
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.62
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.73
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 1.0
rrl 1474288 n.631C>T non_coding_transcript_exon_variant 1.0
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.67
rrl 1474315 n.658A>G non_coding_transcript_exon_variant 0.67
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.88
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.88
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.89
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.91
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.94
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 0.88
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.94
rrl 1474413 n.757_776delCCCACACGCGCATACGCGCG non_coding_transcript_exon_variant 1.0
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 1.0
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 1.0
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.93
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.93
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.94
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.94
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.94
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.95
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.81
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.15
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.15
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.96
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.16
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.16
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.8
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.79
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.77
rrl 1474634 n.977T>G non_coding_transcript_exon_variant 0.77
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.97
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 0.19
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.94
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.22
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.68
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.9
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.22
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.65
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.88
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.88
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.88
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.25
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.75
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 0.82
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.21
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.97
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.93
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.93
rrl 1475026 n.1369G>C non_coding_transcript_exon_variant 0.67
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 0.75
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 0.8
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.8
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 0.8
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 0.8
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.89
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.92
rrl 1475109 n.1452C>T non_coding_transcript_exon_variant 0.17
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.92
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 1.0
rrl 1475172 n.1515A>G non_coding_transcript_exon_variant 0.86
rrl 1475488 n.1831G>C non_coding_transcript_exon_variant 1.0
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 1.0
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 1.0
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 1.0
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 1.0
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 1.0
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 1.0
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 1.0
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.6
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.6
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 1.0
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.67
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.75
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 1.0
rrl 1475754 n.2097G>A non_coding_transcript_exon_variant 0.78
rrl 1475774 n.2117C>T non_coding_transcript_exon_variant 0.8
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.93
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.69
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.9
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.72
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.84
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.79
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.79
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.73
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.62
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.62
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.5
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.71
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.5
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.5
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.5
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.67
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.67
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.67
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.5
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.5
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.5
rrl 1476035 n.2378G>T non_coding_transcript_exon_variant 0.5
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.5
rrl 1476046 n.2389G>C non_coding_transcript_exon_variant 0.5
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.5
rrl 1476058 n.2401T>C non_coding_transcript_exon_variant 0.5
rrl 1476059 n.2402G>C non_coding_transcript_exon_variant 0.5
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.67
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.56
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.92
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 0.83
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.88
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.12
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.75
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.75
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.73
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.71
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.18
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.69
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.25
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.2
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 0.14
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.35
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.47
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.35
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.35
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.35
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.82
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.35
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.25
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.18
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.55
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.18
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.41
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.1
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.82
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.85
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.5
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.44
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.83
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.39
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.95
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.96
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.95
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.14
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.65
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.93
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.86
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.95
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.5
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.15
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.76
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.94
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.94
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.32
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.16
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.18
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.81
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.81
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.78
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.79
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.77
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.77
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.77
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.73
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.74
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.67
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.57
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.5
rrl 1476675 n.3018C>A non_coding_transcript_exon_variant 0.33
rrl 1476680 n.3023T>C non_coding_transcript_exon_variant 0.27
rpsA 1833661 c.120A>G synonymous_variant 0.14
rpsA 1833667 c.126C>T synonymous_variant 0.15
rpsA 1833668 p.Ile43Val missense_variant 0.15
rpsA 1833676 c.135A>G synonymous_variant 0.17
rpsA 1833679 c.138G>C synonymous_variant 0.17
rpsA 1833685 c.144G>T synonymous_variant 0.14
rpsA 1833688 c.147C>T synonymous_variant 0.14
rpsA 1833694 c.153G>C synonymous_variant 0.21
rpsA 1833727 c.186G>C synonymous_variant 0.32
rpsA 1833732 p.Pro64Leu missense_variant 0.27
rpsA 1833736 c.195C>T synonymous_variant 0.28
rpsA 1833742 c.201A>G synonymous_variant 0.28
rpsA 1833770 p.Asn77Asp missense_variant 0.25
rpsA 1833776 p.Val79Ile missense_variant 0.21
rpsA 1833781 c.240T>C synonymous_variant 0.2
rpsA 1833790 c.249T>C synonymous_variant 0.22
rpsA 1833797 p.Val86Ile missense_variant 0.17
rpsA 1834009 c.468C>T synonymous_variant 0.15
rpsA 1834012 c.471G>C synonymous_variant 0.15
rpsA 1834015 c.474G>T synonymous_variant 0.15
rpsA 1834024 c.483G>C synonymous_variant 0.14
rpsA 1834034 p.Ile165Val missense_variant 0.12
rpsA 1834040 p.Lys167Arg missense_variant 0.14
rpsA 1834046 p.Ile169Leu missense_variant 0.12
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834195 c.654G>C synonymous_variant 0.19
rpsA 1834228 c.687C>T synonymous_variant 0.35
rpsA 1834231 c.690T>C synonymous_variant 0.36
rpsA 1834234 c.693G>C synonymous_variant 0.39
rpsA 1834240 c.699T>C synonymous_variant 0.24
rpsA 1834246 c.705G>T synonymous_variant 0.24
rpsA 1834249 c.708T>C synonymous_variant 0.41
rpsA 1834261 c.720A>G synonymous_variant 0.38
rpsA 1834264 c.723G>C synonymous_variant 0.37
rpsA 1834285 c.744G>C synonymous_variant 0.12
rpsA 1834294 c.753G>C synonymous_variant 0.27
rpsA 1834298 p.Gln253Glu missense_variant 0.28
rpsA 1834303 c.762T>C synonymous_variant 0.11
rpsA 1834306 c.765T>C synonymous_variant 0.21
rpsA 1834307 p.Asp256Asn missense_variant 0.13
rpsA 1834318 c.777C>G synonymous_variant 0.13
rpsA 1834327 c.786G>T synonymous_variant 0.12
rpsA 1834451 c.910T>C synonymous_variant 0.12
rpsA 1834456 c.915T>C synonymous_variant 0.12
rpsA 1834459 c.918G>C synonymous_variant 0.13
rpsA 1834465 c.924T>C synonymous_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290147 c.-906T>C upstream_gene_variant 0.11
ald 3086700 c.-120G>T upstream_gene_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448615 p.Arg38Trp missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
alr 3841120 p.Arg101Ser missense_variant 1.0
clpC1 4040051 c.654C>G synonymous_variant 0.11
clpC1 4040057 c.648C>G synonymous_variant 0.14
clpC1 4040063 c.642G>C synonymous_variant 0.14
clpC1 4040066 c.639G>C synonymous_variant 0.14
clpC1 4040069 c.636G>C synonymous_variant 0.15
clpC1 4040090 c.615T>C synonymous_variant 0.17
clpC1 4040096 c.609G>C synonymous_variant 0.17
clpC1 4040110 c.595C>A synonymous_variant 0.18
clpC1 4040114 p.Ile197Met missense_variant 0.17
clpC1 4040117 c.588A>G synonymous_variant 0.13
clpC1 4040125 p.Glu194Lys missense_variant 0.12
embC 4240550 p.Lys230Glu missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0