TB-Profiler result

Run: SRR18003015
Summary

Run ID: SRR18003015

Sample name:

Date: 03-04-2023 19:14:41

Number of reads: 1951750

Percentage reads mapped: 40.66

Strain: lineage2.2.1

Drug-resistance: MDR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761089 p.Ser428Thr missense_variant 0.12 rifampicin
rpoB 761127 p.Ser441Ala missense_variant 0.13 rifampicin
rpoB 761155 p.Ser450Leu missense_variant 0.85 rifampicin
rpsL 781822 p.Lys88Arg missense_variant 0.96 streptomycin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.31 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.36 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.46 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.82 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
katG 2155633 p.Ser160Leu missense_variant 0.18 isoniazid
pncA 2288817 p.Thr142Arg missense_variant 1.0 pyrazinamide
embB 4247429 p.Met306Val missense_variant 0.93 ethambutol
ethA 4327250 c.223delA frameshift_variant 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7789 p.Pro163Leu missense_variant 0.12
gyrA 7993 p.Ala231Val missense_variant 0.12
gyrA 8116 p.Thr272Ile missense_variant 0.17
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575807 p.His154Tyr missense_variant 0.15
mshA 576108 p.Ala254Gly missense_variant 0.42
ccsA 620389 c.499C>T synonymous_variant 0.15
ccsA 620527 p.Ala213Thr missense_variant 0.12
rpoB 760871 c.1065C>T synonymous_variant 0.14
rpoB 761054 c.1248G>C synonymous_variant 0.12
rpoB 761060 c.1254C>G synonymous_variant 0.12
rpoB 761075 c.1269G>A synonymous_variant 0.12
rpoB 761096 c.1290G>C synonymous_variant 0.14
rpoB 761102 c.1296A>G synonymous_variant 0.14
rpoB 761132 c.1326G>C synonymous_variant 0.14
rpoB 761133 c.1327T>C synonymous_variant 0.14
rpoB 761150 c.1344A>C synonymous_variant 0.13
rpoB 761159 c.1353G>C synonymous_variant 0.14
rpoB 761165 c.1359G>C synonymous_variant 0.12
rpoB 761174 c.1368T>C synonymous_variant 0.12
rpoB 761213 c.1407G>A synonymous_variant 0.14
rpoB 761710 p.Val635Asp missense_variant 0.24
rpoB 761713 p.Val636Asp missense_variant 0.2
rpoB 761862 p.Ala686Thr missense_variant 0.13
rpoB 762148 c.2345delG frameshift_variant 0.15
rpoC 762839 c.-531G>A upstream_gene_variant 0.14
rpoC 762947 c.-423C>G upstream_gene_variant 0.12
rpoC 762971 c.-399G>C upstream_gene_variant 0.12
rpoC 762980 c.-390T>C upstream_gene_variant 0.15
rpoC 763031 c.-339T>C upstream_gene_variant 0.96
rpoC 763386 p.Phe6Tyr missense_variant 0.15
rpoC 763393 c.24T>C synonymous_variant 0.15
rpoC 763396 c.27A>G synonymous_variant 0.2
rpoC 763405 c.36C>T synonymous_variant 0.2
rpoC 763408 c.39T>G synonymous_variant 0.2
rpoC 763411 c.42T>C synonymous_variant 0.2
rpoC 763414 c.45T>A synonymous_variant 0.2
rpoC 763417 c.48C>A synonymous_variant 0.2
rpoC 763420 c.51G>C synonymous_variant 0.2
rpoC 763423 p.Glu18Asp missense_variant 0.2
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 0.2
rpoC 763434 p.Gln22Arg missense_variant 0.2
rpoC 763442 p.Tyr25Lys missense_variant 0.18
rpoC 763456 c.87A>G synonymous_variant 0.18
rpoC 763468 c.99G>C synonymous_variant 0.18
rpoC 763483 c.114G>C synonymous_variant 0.12
rpoC 763486 c.117T>C synonymous_variant 0.18
rpoC 764165 p.Glu266Lys missense_variant 0.2
rpoC 764485 c.1116G>A synonymous_variant 0.12
rpoC 764573 p.Leu402Ile missense_variant 0.14
rpoC 764578 c.1209C>G synonymous_variant 0.14
rpoC 764581 c.1212T>C synonymous_variant 0.15
rpoC 764582 p.Leu405Met missense_variant 0.16
rpoC 764647 c.1278C>T synonymous_variant 0.12
rpoC 764653 c.1284G>C synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775988 c.2493G>A synonymous_variant 0.18
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777748 p.Gly245Arg missense_variant 0.12
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303435 p.Ser169Pro missense_variant 0.12
fbiC 1304141 p.Ala404Val missense_variant 0.12
fbiC 1305065 c.2138_2139delTG frameshift_variant 0.17
Rv1258c 1406450 c.891C>T synonymous_variant 0.2
Rv1258c 1406513 c.828G>A synonymous_variant 0.17
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.19
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.27
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.15
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.2
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.23
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.14
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.16
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.22
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.57
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.16
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.32
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.44
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.27
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.49
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.14
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 0.12
rrs 1472282 n.437T>G non_coding_transcript_exon_variant 0.13
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.22
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.22
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.12
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.29
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.15
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.15
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.13
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.23
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.31
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.18
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.18
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.32
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.21
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.5
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.33
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.5
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.19
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.19
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.2
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.2
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.36
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.33
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.29
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.28
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.22
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.28
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.24
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.23
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.3
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.14
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.54
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.33
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.24
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.23
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.32
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.35
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.67
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.63
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.34
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.4
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.34
rrs 1472680 n.835C>T non_coding_transcript_exon_variant 0.21
rrs 1472689 n.844C>T non_coding_transcript_exon_variant 0.2
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.33
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.39
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.13
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.35
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.44
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.35
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.38
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.4
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.27
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.14
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.14
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.12
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.17
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.46
rrs 1472951 n.1106T>C non_coding_transcript_exon_variant 0.19
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.22
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.18
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.32
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.22
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.52
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.72
rrs 1472970 n.1126delG non_coding_transcript_exon_variant 0.15
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.44
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.61
rrs 1472974 n.1129A>C non_coding_transcript_exon_variant 0.19
rrs 1472975 n.1130T>G non_coding_transcript_exon_variant 0.14
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.17
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.44
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.26
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.52
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.32
rrs 1473001 n.1156G>C non_coding_transcript_exon_variant 0.17
rrs 1473002 n.1157G>A non_coding_transcript_exon_variant 0.18
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.21
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.31
rrs 1473008 n.1163C>T non_coding_transcript_exon_variant 0.18
rrs 1473009 n.1164T>G non_coding_transcript_exon_variant 0.18
rrs 1473020 n.1175T>C non_coding_transcript_exon_variant 0.15
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.73
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.43
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.66
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.19
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.47
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.14
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.4
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.39
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.14
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.42
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.34
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.38
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.39
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.48
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.36
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.57
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.65
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.7
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.12
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.14
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.2
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.63
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.64
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.45
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.58
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.14
rrs 1473291 n.1446G>C non_coding_transcript_exon_variant 0.18
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.17
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.19
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.46
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.34
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.5
rrl 1473406 n.-252A>G upstream_gene_variant 0.11
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.17
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.17
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.11
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.11
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.15
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.24
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.16
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.2
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.16
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.11
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.17
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.11
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.19
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.19
rrl 1474353 n.696A>T non_coding_transcript_exon_variant 0.18
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.2
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.2
rrl 1474425 n.768A>G non_coding_transcript_exon_variant 0.32
rrl 1474428 n.771C>T non_coding_transcript_exon_variant 0.36
rrl 1474438 n.781A>G non_coding_transcript_exon_variant 0.17
rrl 1474449 n.792G>A non_coding_transcript_exon_variant 0.13
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.27
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.41
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.43
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.39
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.42
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.46
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.52
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.52
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.52
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.66
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.55
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.59
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.55
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.5
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.36
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.35
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.24
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.45
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.58
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.58
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.34
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.24
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.14
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.14
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.4
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.13
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.45
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.44
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.36
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.4
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.14
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.43
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.31
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.43
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.14
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.54
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.39
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.57
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.15
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.47
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.44
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.39
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.53
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.13
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.28
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.42
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.36
rrl 1474933 n.1276A>G non_coding_transcript_exon_variant 0.18
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 0.18
rrl 1475485 n.1828C>T non_coding_transcript_exon_variant 0.13
rrl 1475640 n.1983G>C non_coding_transcript_exon_variant 0.18
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.14
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.18
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.15
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.16
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.32
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.14
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.12
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.24
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.32
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.25
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.28
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.27
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.28
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.33
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.2
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.39
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.51
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.61
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.68
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.34
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.24
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.27
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.76
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.76
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.28
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.81
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.79
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.73
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.27
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.76
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.49
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.7
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.7
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.7
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.55
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.65
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.51
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.56
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.56
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.55
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.34
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.3
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.3
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.29
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.29
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.29
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.29
rrl 1476135 n.2478T>C non_coding_transcript_exon_variant 0.16
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.32
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.48
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.35
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.33
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.64
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.44
rrl 1476196 n.2539C>G non_coding_transcript_exon_variant 0.32
rrl 1476197 n.2540T>C non_coding_transcript_exon_variant 0.26
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.41
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.41
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.41
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.47
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.35
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.41
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.14
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 0.33
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.28
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.26
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.45
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.59
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.23
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.5
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.23
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.91
rrl 1476279 n.2622G>T non_coding_transcript_exon_variant 0.18
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.59
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.21
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.38
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.88
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.85
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.85
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.78
rrl 1476299 n.2642C>A non_coding_transcript_exon_variant 0.3
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.18
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.3
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.36
rrl 1476308 n.2651G>T non_coding_transcript_exon_variant 0.29
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.85
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.86
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.36
rrl 1476319 n.2662C>T non_coding_transcript_exon_variant 0.19
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.67
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.71
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.4
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.71
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.43
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.65
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.68
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.4
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.72
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.76
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.31
rrl 1476420 n.2763G>A non_coding_transcript_exon_variant 0.21
rrl 1476422 n.2765C>G non_coding_transcript_exon_variant 0.21
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.46
rrl 1476427 n.2770G>T non_coding_transcript_exon_variant 0.2
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.77
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.7
rrl 1476431 n.2774G>C non_coding_transcript_exon_variant 0.2
rrl 1476433 n.2776C>T non_coding_transcript_exon_variant 0.19
rrl 1476450 n.2793T>C non_coding_transcript_exon_variant 0.19
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.53
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.74
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.71
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.14
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.18
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.51
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.15
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.15
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.56
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.6
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.56
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.58
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.23
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.53
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.63
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.12
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.37
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.19
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.28
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.28
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.24
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.17
fabG1 1673298 c.-142A>T upstream_gene_variant 0.13
inhA 1674220 p.Gly7Ser missense_variant 0.12
inhA 1674382 p.Leu61Phe missense_variant 0.12
rpsA 1833648 p.Gly36Val missense_variant 0.16
rpsA 1833651 p.Asp37Ala missense_variant 0.16
rpsA 1833970 c.429G>T synonymous_variant 0.13
rpsA 1833979 c.438T>C synonymous_variant 0.12
rpsA 1833991 c.450C>T synonymous_variant 0.13
rpsA 1833994 c.453G>C synonymous_variant 0.12
rpsA 1833997 c.456G>C synonymous_variant 0.14
rpsA 1834000 c.459G>C synonymous_variant 0.14
rpsA 1834009 c.468C>T synonymous_variant 0.14
rpsA 1834012 c.471G>C synonymous_variant 0.15
rpsA 1834015 c.474G>C synonymous_variant 0.13
rpsA 1834024 c.483G>C synonymous_variant 0.14
rpsA 1834025 p.Gln162Ala missense_variant 0.14
rpsA 1834039 c.498C>T synonymous_variant 0.14
rpsA 1834040 p.Lys167Arg missense_variant 0.14
rpsA 1834051 c.510G>A synonymous_variant 0.14
rpsA 1834054 c.513C>G synonymous_variant 0.14
rpsA 1834069 c.528G>C synonymous_variant 0.13
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834294 c.753G>C synonymous_variant 0.13
rpsA 1834298 p.Gln253Glu missense_variant 0.12
rpsA 1834306 c.765T>C synonymous_variant 0.12
rpsA 1834307 p.Asp256Gln missense_variant 0.12
rpsA 1834312 c.771G>A synonymous_variant 0.12
rpsA 1834348 c.807T>C synonymous_variant 0.18
rpsA 1834354 c.813G>C synonymous_variant 0.18
rpsA 1834357 c.816T>C synonymous_variant 0.17
rpsA 1834360 c.819G>C synonymous_variant 0.17
rpsA 1834361 c.820T>C synonymous_variant 0.16
rpsA 1834366 c.825A>G synonymous_variant 0.16
rpsA 1834375 c.834G>C synonymous_variant 0.16
rpsA 1834387 c.846C>T synonymous_variant 0.16
rpsA 1834411 c.870T>C synonymous_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102814 p.Arg77Cys missense_variant 0.12
ndh 2103032 c.10delC frameshift_variant 0.12
katG 2154114 c.1998C>T synonymous_variant 0.15
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155308 c.804C>T synonymous_variant 0.12
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169425 c.1188G>A synonymous_variant 0.12
PPE35 2169558 p.Phe352Ser missense_variant 0.2
PPE35 2170048 p.Leu189Val missense_variant 0.29
PPE35 2170053 p.Thr187Ser missense_variant 0.3
Rv1979c 2222360 p.Leu269Phe missense_variant 0.12
Rv1979c 2223216 c.-52C>T upstream_gene_variant 0.17
Rv1979c 2223228 c.-64C>G upstream_gene_variant 0.13
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290084 c.-843T>A upstream_gene_variant 0.14
pncA 2290112 c.-871C>T upstream_gene_variant 0.2
pncA 2290167 c.-926G>T upstream_gene_variant 0.15
kasA 2519198 c.1084C>T synonymous_variant 0.15
kasA 2519206 c.1092C>T synonymous_variant 0.14
ahpC 2726175 c.-18T>A upstream_gene_variant 0.15
ahpC 2726186 c.-7G>A upstream_gene_variant 0.17
ahpC 2726486 c.294A>G synonymous_variant 0.11
folC 2747354 c.244delG frameshift_variant 0.17
folC 2747362 c.237G>A synonymous_variant 0.15
pepQ 2859658 p.Ala254Val missense_variant 0.14
pepQ 2859844 p.Thr192Met missense_variant 0.14
pepQ 2859938 p.Gly161Ser missense_variant 0.12
pepQ 2860167 c.252C>T synonymous_variant 0.95
ribD 2987157 c.320delA frameshift_variant 0.12
Rv2752c 3065186 c.1006T>C synonymous_variant 0.13
Rv2752c 3066192 c.-1A>G upstream_gene_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339726 c.609A>C synonymous_variant 0.21
Rv3083 3449158 p.Ser219Pro missense_variant 0.11
Rv3083 3449293 c.790C>T synonymous_variant 0.12
Rv3083 3449467 p.Glu322Lys missense_variant 0.25
Rv3083 3449733 c.1230G>T synonymous_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.92
fprA 3474094 p.Glu30Lys missense_variant 0.14
fprA 3474180 c.174C>T synonymous_variant 0.13
fprA 3474734 p.Lys243Met missense_variant 0.12
fprA 3474792 c.786G>A synonymous_variant 0.13
fprA 3475360 c.1356delG frameshift_variant 0.13
whiB7 3568552 p.Cys43Phe missense_variant 0.13
whiB7 3568679 p.Val1Met missense_variant 0.17
Rv3236c 3612341 p.Ala259Val missense_variant 0.13
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
Rv3236c 3613277 c.-161C>T upstream_gene_variant 0.25
fbiB 3640879 c.-656C>T upstream_gene_variant 1.0
alr 3840524 p.Trp299Cys missense_variant 0.12
alr 3840793 p.Val210Ile missense_variant 0.15
rpoA 3877733 p.Arg259Trp missense_variant 0.18
rpoA 3878567 c.-60C>G upstream_gene_variant 0.14
rpoA 3878639 c.-132C>G upstream_gene_variant 0.19
clpC1 4040138 c.567G>A synonymous_variant 0.15
clpC1 4040714 c.-10G>T upstream_gene_variant 0.18
panD 4044356 c.-75T>C upstream_gene_variant 0.11
embC 4240421 p.Glu187Lys missense_variant 0.15
embC 4240725 p.Gly288Glu missense_variant 0.19
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4245069 p.Val613Met missense_variant 0.13
embA 4245123 p.Gly631Arg missense_variant 0.12
embA 4245933 p.Pro901Ser missense_variant 0.14
embB 4246544 p.Thr11Pro missense_variant 0.4
embB 4246548 p.Pro12Gln missense_variant 0.55
embB 4246555 c.42G>C synonymous_variant 0.56
embB 4246556 p.Ala15Pro missense_variant 0.56
embB 4246563 p.Leu17Trp missense_variant 0.89
embB 4246567 c.54G>T synonymous_variant 0.83
aftB 4267647 p.Asp397Gly missense_variant 1.0
aftB 4268030 c.807G>A synonymous_variant 0.14
aftB 4268695 p.Val48Phe missense_variant 0.13
aftB 4269153 c.-317C>T upstream_gene_variant 0.12
ethA 4326474 p.Pro334Ala missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0