TB-Profiler result

Run: ERR4819864
Summary

Run ID: ERR4819864

Sample name:

Date: 01-04-2023 16:20:54

Number of reads: 2185029

Percentage reads mapped: 71.2

Strain: lineage1.1.3.1

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1 Indo-Oceanic EAI RD239 1.0
lineage1.1 Indo-Oceanic EAI3;EAI4;EAI5;EAI6 RD239 1.0
lineage1.1.3 Indo-Oceanic EAI6 RD239 1.0
lineage1.1.3.1 Indo-Oceanic NA RD239 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761033 p.Gln409His missense_variant 0.1 rifampicin
rpoB 761127 p.Ser441Ala missense_variant 0.16 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.46 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 1.0
gyrB 6125 p.Gly296Arg missense_variant 0.17
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575920 c.573C>T synonymous_variant 1.0
mshA 576093 p.Pro249Leu missense_variant 1.0
rpoB 761021 c.1215G>C synonymous_variant 0.1
rpoB 761037 c.1231T>C synonymous_variant 0.1
rpoB 761054 c.1248G>C synonymous_variant 0.22
rpoB 761058 p.Val418Thr missense_variant 0.21
rpoB 761084 c.1278C>A synonymous_variant 0.14
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.24
rpoB 761102 c.1296A>G synonymous_variant 0.24
rpoB 761132 c.1326G>C synonymous_variant 0.15
rpoB 761133 c.1327T>C synonymous_variant 0.12
rpoB 761564 c.1758G>C synonymous_variant 0.11
rpoB 761570 c.1764T>C synonymous_variant 0.11
rpoB 761600 c.1794T>C synonymous_variant 0.15
rpoB 761612 c.1806G>C synonymous_variant 0.14
rpoB 761615 c.1809A>G synonymous_variant 0.12
rpoB 761633 c.1827G>C synonymous_variant 0.19
rpoB 761650 p.Ser615Thr missense_variant 0.16
rpoB 762194 c.2388G>C synonymous_variant 0.12
rpoB 762212 c.2406G>C synonymous_variant 0.14
rpoB 762218 c.2412T>C synonymous_variant 0.11
rpoB 762245 c.2439G>C synonymous_variant 0.15
rpoC 762887 c.-483G>C upstream_gene_variant 0.14
rpoC 762896 c.-474G>C upstream_gene_variant 0.15
rpoC 762926 c.-444C>G upstream_gene_variant 0.15
rpoC 762938 c.-432G>C upstream_gene_variant 0.16
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763078 p.Val1091Ala missense_variant 0.11
rpoC 763103 c.-267G>C upstream_gene_variant 0.12
rpoC 763468 c.99G>C synonymous_variant 0.14
rpoC 763483 c.114G>C synonymous_variant 0.16
rpoC 763486 c.117T>C synonymous_variant 0.16
rpoC 763504 c.135C>G synonymous_variant 0.14
rpoC 763507 c.138G>C synonymous_variant 0.3
rpoC 763528 c.159G>C synonymous_variant 0.2
rpoC 763531 c.162G>C synonymous_variant 0.31
rpoC 763534 c.165T>C synonymous_variant 0.31
rpoC 763537 c.168C>G synonymous_variant 0.17
rpoC 763546 c.177A>G synonymous_variant 0.29
rpoC 763550 p.Tyr61Ala missense_variant 0.29
rpoC 763558 c.189C>T synonymous_variant 0.22
rpoC 763570 c.201G>C synonymous_variant 0.39
rpoC 763578 p.Phe70Tyr missense_variant 0.3
rpoC 763589 p.Ile74Val missense_variant 0.12
rpoC 763609 c.240C>G synonymous_variant 0.14
rpoC 763615 c.246G>C synonymous_variant 0.12
rpoC 763622 p.Ala85Ser missense_variant 0.2
rpoC 763633 c.264T>C synonymous_variant 0.1
rpoC 763636 c.267T>C synonymous_variant 0.11
rpoC 763642 c.273G>C synonymous_variant 0.12
rpoC 763647 p.Gly93Ala missense_variant 0.17
rpoC 763655 p.Glu96Lys missense_variant 0.15
rpoC 763660 c.291T>G synonymous_variant 0.13
rpoC 763699 c.330G>T synonymous_variant 0.12
rpoC 763708 c.339G>C synonymous_variant 0.17
rpoC 763714 c.345G>C synonymous_variant 0.11
rpoC 763717 c.348T>C synonymous_variant 0.12
rpoC 763884 p.Ala172Val missense_variant 1.0
rpoC 763886 c.517C>A synonymous_variant 1.0
rpoC 764485 c.1116G>C synonymous_variant 0.14
rpoC 764509 c.1140G>C synonymous_variant 0.24
rpoC 764521 c.1152T>C synonymous_variant 0.29
rpoC 764527 c.1158C>T synonymous_variant 0.15
rpoC 764536 c.1167G>C synonymous_variant 0.17
rpoC 764539 c.1170C>G synonymous_variant 0.17
rpoC 764548 c.1179G>C synonymous_variant 0.31
rpoC 764549 p.Pro394Val missense_variant 0.33
rpoC 764560 c.1191T>C synonymous_variant 0.32
rpoC 764566 c.1197C>G synonymous_variant 0.35
rpoC 764572 c.1203G>C synonymous_variant 0.35
rpoC 764575 c.1206T>G synonymous_variant 0.36
rpoC 764581 c.1212T>C synonymous_variant 0.41
rpoC 764582 p.Leu405Met missense_variant 0.4
rpoC 764605 c.1236G>C synonymous_variant 0.44
rpoC 764611 c.1242G>C synonymous_variant 0.26
rpoC 764620 c.1251G>C synonymous_variant 0.18
rpoC 764623 c.1254C>G synonymous_variant 0.35
rpoC 764632 c.1263T>C synonymous_variant 0.35
rpoC 764635 c.1266C>G synonymous_variant 0.29
rpoC 764644 c.1275G>C synonymous_variant 0.12
rpoC 764650 c.1281G>T synonymous_variant 0.12
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.12
rpoC 764662 c.1293G>C synonymous_variant 0.12
rpoC 764671 c.1302G>C synonymous_variant 0.19
rpoC 765171 p.Pro601Leu missense_variant 1.0
rpoC 765230 p.Ala621Thr missense_variant 1.0
rpoC 765923 p.Asn852Ala missense_variant 0.2
rpoC 765937 c.2568T>C synonymous_variant 0.2
rpoC 765940 c.2571A>T synonymous_variant 0.2
rpoC 765947 c.2578T>C synonymous_variant 0.28
rpoC 765958 c.2589C>G synonymous_variant 0.3
rpoC 765962 c.2593T>C synonymous_variant 0.33
rpoC 765967 c.2598C>T synonymous_variant 0.2
rpoC 765982 c.2613C>G synonymous_variant 0.15
rpoC 765988 c.2619G>C synonymous_variant 0.27
rpoC 765994 c.2625A>G synonymous_variant 0.13
rpoC 765997 c.2628T>C synonymous_variant 0.11
rpoC 766009 c.2640G>C synonymous_variant 0.16
rpoC 766345 c.2976T>C synonymous_variant 0.11
rpoC 766351 c.2982C>G synonymous_variant 0.12
rpoC 766361 p.Val998Ile missense_variant 0.12
rpoC 766384 c.3015A>G synonymous_variant 0.12
rpoC 766393 c.3024C>G synonymous_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781679 c.120C>T synonymous_variant 0.93
rpsL 781754 c.195G>C synonymous_variant 0.11
rpsL 781760 c.201T>C synonymous_variant 0.1
rplC 800703 c.-106T>C upstream_gene_variant 0.11
rplC 800715 c.-94A>G upstream_gene_variant 0.1
rplC 800720 c.-89T>C upstream_gene_variant 0.1
rplC 800723 c.-86C>G upstream_gene_variant 0.11
embR 1417019 p.Cys110Tyr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471961 n.116C>T non_coding_transcript_exon_variant 0.13
rrs 1471967 n.122G>A non_coding_transcript_exon_variant 0.21
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.17
rrs 1471975 n.130G>A non_coding_transcript_exon_variant 0.14
rrs 1471978 n.133C>T non_coding_transcript_exon_variant 0.14
rrs 1471980 n.135G>T non_coding_transcript_exon_variant 0.15
rrs 1471981 n.136C>T non_coding_transcript_exon_variant 0.36
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.17
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.17
rrs 1471996 n.151C>T non_coding_transcript_exon_variant 0.29
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.29
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.41
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.41
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.75
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.12
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.29
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.64
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.67
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.66
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.11
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.89
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.9
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.47
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.71
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.39
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.44
rrs 1472188 n.343A>G non_coding_transcript_exon_variant 0.1
rrs 1472207 n.362A>G non_coding_transcript_exon_variant 0.11
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.11
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.8
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.64
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.64
rrs 1472274 n.429A>G non_coding_transcript_exon_variant 0.4
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.67
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.67
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.67
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.94
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.2
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.95
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.97
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.85
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.95
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.2
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.96
rrs 1472584 n.739A>C non_coding_transcript_exon_variant 0.29
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.78
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.75
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.37
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.33
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.64
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.43
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.43
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.67
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.17
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.52
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.5
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.52
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.55
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.45
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.53
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.43
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.53
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.59
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.9
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.11
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.58
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.83
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.25
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.78
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.22
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.48
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.37
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.6
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.62
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.82
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.57
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.78
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.81
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.17
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.98
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.91
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.95
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.95
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.84
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.82
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.89
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.88
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.88
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.77
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.87
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.12
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.23
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.65
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.11
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.55
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.33
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.21
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.64
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.16
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.31
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.3
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.32
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.51
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.52
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.68
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.59
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.47
rrs 1473288 n.1443C>G non_coding_transcript_exon_variant 0.41
rrs 1473289 n.1444_1445insTTTG non_coding_transcript_exon_variant 0.42
rrs 1473293 n.1449delA non_coding_transcript_exon_variant 0.5
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.5
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.64
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.11
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.11
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.61
rrs 1473365 n.1520C>A non_coding_transcript_exon_variant 0.13
rrl 1473384 n.-274A>G upstream_gene_variant 0.44
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 1.0
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 1.0
rrl 1474183 n.527delC non_coding_transcript_exon_variant 1.0
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 1.0
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.83
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.33
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.33
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.33
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.33
rrl 1474275 n.618T>C non_coding_transcript_exon_variant 0.8
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.5
rrl 1474315 n.658A>G non_coding_transcript_exon_variant 0.67
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 1.0
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 1.0
rrl 1474406 n.749T>C non_coding_transcript_exon_variant 0.62
rrl 1474413 n.757_777delCCCACACGCGCATACGCGCGT non_coding_transcript_exon_variant 1.0
rrl 1474413 n.757_776delCCCACACGCGCATACGCGCG non_coding_transcript_exon_variant 1.0
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 1.0
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.12
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 0.88
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 1.0
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.81
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.12
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.89
rrl 1474501 n.844A>G non_coding_transcript_exon_variant 0.11
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.89
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.81
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.94
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.9
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.91
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.38
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.46
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.35
rrl 1474581 n.924C>T non_coding_transcript_exon_variant 0.35
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.12
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.85
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.82
rrl 1474634 n.977T>G non_coding_transcript_exon_variant 0.82
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 1.0
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 1.0
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474774 n.1117A>G non_coding_transcript_exon_variant 0.26
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.26
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.32
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.93
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.1
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.21
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.21
rrl 1474806 n.1149A>C non_coding_transcript_exon_variant 0.1
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.16
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.86
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.86
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.79
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.44
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.71
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.17
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.17
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.83
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.76
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 1.0
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 1.0
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 1.0
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 1.0
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 1.0
rrl 1475172 n.1515A>G non_coding_transcript_exon_variant 1.0
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.75
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 0.6
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 0.67
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 0.67
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 0.67
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 0.67
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.6
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.67
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.67
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.5
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.67
rrl 1475574 n.1917C>G non_coding_transcript_exon_variant 0.25
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 1.0
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 1.0
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 1.0
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.33
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.54
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.9
rrl 1475754 n.2097G>A non_coding_transcript_exon_variant 0.9
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 1.0
rrl 1475774 n.2117C>T non_coding_transcript_exon_variant 0.9
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.76
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.75
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 0.44
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.57
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.77
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.36
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.18
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.18
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.22
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.6
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.6
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.6
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.5
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.29
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.44
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.5
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.48
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.63
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.74
rrl 1476187 n.2530T>C non_coding_transcript_exon_variant 0.59
rrl 1476188 n.2531C>T non_coding_transcript_exon_variant 0.11
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.82
rrl 1476195 n.2538C>T non_coding_transcript_exon_variant 0.12
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.82
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.12
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.75
rrl 1476211 n.2554G>A non_coding_transcript_exon_variant 0.12
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.25
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.38
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.39
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.38
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.58
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.45
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.5
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.77
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.96
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.82
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.96
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.86
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.5
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.5
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.5
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.5
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.5
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.5
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.56
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.83
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.6
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.72
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.24
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.17
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.12
rrl 1476458 n.2801T>C non_coding_transcript_exon_variant 0.21
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.55
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.21
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.52
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.33
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.29
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.21
rrl 1476548 n.2891T>C non_coding_transcript_exon_variant 0.17
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.5
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.58
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.46
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.42
rrl 1476609 n.2952G>A non_coding_transcript_exon_variant 0.15
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.59
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.48
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.52
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.36
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.23
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.16
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.11
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.11
rrl 1476675 n.3018C>A non_coding_transcript_exon_variant 0.15
rrl 1476679 n.3022T>A non_coding_transcript_exon_variant 0.15
rrl 1476763 n.3106G>T non_coding_transcript_exon_variant 0.17
rpsA 1833727 c.186G>C synonymous_variant 0.26
rpsA 1833732 p.Pro64Leu missense_variant 0.24
rpsA 1833736 c.195C>T synonymous_variant 0.24
rpsA 1833742 c.201A>G synonymous_variant 0.25
rpsA 1833934 c.393C>T synonymous_variant 0.11
rpsA 1833994 c.453G>C synonymous_variant 0.15
rpsA 1834000 c.459G>C synonymous_variant 0.12
rpsA 1834009 c.468C>T synonymous_variant 0.25
rpsA 1834012 c.471G>C synonymous_variant 0.19
rpsA 1834024 c.483G>C synonymous_variant 0.17
rpsA 1834034 p.Ile165Val missense_variant 0.17
rpsA 1834040 p.Lys167Arg missense_variant 0.13
rpsA 1834046 p.Ile169Leu missense_variant 0.14
rpsA 1834054 c.513C>G synonymous_variant 0.14
rpsA 1834195 c.654G>C synonymous_variant 0.1
rpsA 1834213 c.672G>C synonymous_variant 0.12
rpsA 1834219 c.678C>G synonymous_variant 0.12
rpsA 1834222 c.681T>C synonymous_variant 0.11
rpsA 1834225 c.684C>G synonymous_variant 0.11
rpsA 1834246 c.705G>C synonymous_variant 0.2
rpsA 1834249 c.708T>C synonymous_variant 0.23
rpsA 1834261 c.720A>G synonymous_variant 0.26
rpsA 1834264 c.723G>C synonymous_variant 0.26
rpsA 1834285 c.744G>C synonymous_variant 0.31
rpsA 1834294 c.753G>C synonymous_variant 0.13
rpsA 1834297 c.756C>G synonymous_variant 0.11
rpsA 1834298 p.Gln253Glu missense_variant 0.2
rpsA 1834303 c.762T>C synonymous_variant 0.2
rpsA 1834306 c.765T>C synonymous_variant 0.21
rpsA 1834307 p.Asp256Asn missense_variant 0.21
rpsA 1834327 c.786G>C synonymous_variant 0.25
rpsA 1834333 p.Asp264Glu missense_variant 0.15
rpsA 1834451 c.910T>C synonymous_variant 0.14
rpsA 1834459 c.918G>C synonymous_variant 0.19
rpsA 1834465 c.924T>C synonymous_variant 0.19
rpsA 1834468 c.927A>C synonymous_variant 0.2
rpsA 1834486 p.Glu315Asp missense_variant 0.19
rpsA 1834489 c.948T>C synonymous_variant 0.19
rpsA 1834522 c.981C>T synonymous_variant 0.12
rpsA 1834523 p.Glu328Gln missense_variant 0.12
rpsA 1834609 c.1068T>C synonymous_variant 0.15
rpsA 1834612 c.1071G>C synonymous_variant 0.14
rpsA 1834619 c.1078T>C synonymous_variant 0.14
rpsA 1834633 c.1092A>G synonymous_variant 0.12
rpsA 1834639 c.1098T>C synonymous_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2167983 p.Gly877Asp missense_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2222474 p.Ala231Thr missense_variant 0.13
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
ahpC 2726642 c.450C>T synonymous_variant 0.11
Rv2752c 3064632 c.1560C>T synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339437 p.Ala107Val missense_variant 1.0
Rv3083 3448714 p.Asp71His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
fbiB 3642223 p.Arg230Gln missense_variant 1.0
alr 3841253 c.168C>T synonymous_variant 1.0
rpoA 3878030 p.Gly160Arg missense_variant 0.12
clpC1 4040051 c.654C>G synonymous_variant 0.1
clpC1 4040057 c.648C>G synonymous_variant 0.1
clpC1 4040096 p.Val203Ile missense_variant 0.12
clpC1 4040517 p.Val63Ala missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241042 p.Asn394Asp missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243848 p.Val206Met missense_variant 1.0
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407780 c.423G>A synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0
whiB6 4338429 c.-218_92del frameshift_variant&start_lost 1.0