TB-Profiler result

Run: SRR1173719
Summary

Run ID: SRR1173719

Sample name:

Date: 03-04-2023 03:30:23

Number of reads: 232959

Percentage reads mapped: 6.8

Strain: lineage3

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 0.06
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.51 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.53 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.96 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol
ethA 4326284 p.Leu397Arg missense_variant 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5078 c.-162_-161insG upstream_gene_variant 1.0
gyrB 6248 p.Leu337Ile missense_variant 0.25
gyrB 6302 p.Ala355Thr missense_variant 0.22
gyrA 6307 c.-995T>C upstream_gene_variant 0.3
gyrA 6316 c.-986G>C upstream_gene_variant 0.3
gyrB 6323 p.Val362Leu missense_variant 0.3
gyrA 6326 c.-976_-975delAGinsTC upstream_gene_variant 0.3
gyrA 6331 c.-971A>G upstream_gene_variant 0.33
gyrA 6362 c.-940_-938delTTGinsCTC upstream_gene_variant 0.5
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
ccsA 620307 c.417C>A synonymous_variant 0.5
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 761027 c.1221A>C synonymous_variant 0.67
rpoB 761036 c.1230G>C synonymous_variant 0.75
rpoB 761037 c.1231T>C synonymous_variant 0.75
rpoB 761051 c.1245G>C synonymous_variant 0.75
rpoB 761054 c.1248G>C synonymous_variant 1.0
rpoB 761060 c.1254C>G synonymous_variant 1.0
rpoB 761063 c.1257C>G synonymous_variant 1.0
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 1.0
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0
rpoB 761102 c.1296A>G synonymous_variant 1.0
rpoB 761537 c.1731C>G synonymous_variant 0.5
rpoB 761554 p.Val583Ala missense_variant 0.5
rpoB 761564 c.1758G>C synonymous_variant 0.4
rpoB 761565 p.Met587Leu missense_variant 0.4
rpoB 761570 c.1764T>C synonymous_variant 0.4
rpoB 761573 c.1767C>G synonymous_variant 0.4
rpoB 761579 c.1773G>C synonymous_variant 0.4
rpoB 761600 c.1794T>C synonymous_variant 0.4
rpoB 761603 c.1797C>G synonymous_variant 0.4
rpoB 761612 c.1806G>C synonymous_variant 0.33
rpoB 761615 c.1809A>G synonymous_variant 0.33
rpoB 761963 c.2157G>C synonymous_variant 0.75
rpoB 761974 p.His723Leu missense_variant 0.75
rpoB 762003 p.Asn733Gln missense_variant 0.71
rpoB 762009 p.Leu735Met missense_variant 0.83
rpoB 762015 p.Glu737Ser missense_variant 0.83
rpoB 762026 c.2220G>C synonymous_variant 0.78
rpoB 762053 c.2247T>C synonymous_variant 0.6
rpoB 762057 p.Ile751Val missense_variant 0.6
rpoB 762062 c.2256T>C synonymous_variant 0.6
rpoB 762065 c.2259T>C synonymous_variant 0.6
rpoB 762083 c.2277T>C synonymous_variant 0.44
rpoB 762086 c.2280G>C synonymous_variant 0.4
rpoB 762098 c.2292C>G synonymous_variant 0.4
rpoB 762110 c.2304G>C synonymous_variant 0.4
rpoB 762114 p.Ile770Val missense_variant 0.33
rpoB 762122 p.Asp772Glu missense_variant 0.33
rpoB 762233 c.2427G>C synonymous_variant 0.43
rpoB 762245 c.2439G>C synonymous_variant 0.43
rpoB 762254 c.2448T>C synonymous_variant 0.43
rpoB 762257 c.2451C>G synonymous_variant 0.43
rpoB 762266 c.2460T>C synonymous_variant 0.5
rpoB 762273 p.Ala823Ser missense_variant 0.6
rpoB 762284 c.2478G>C synonymous_variant 0.75
rpoB 762293 c.2487T>G synonymous_variant 0.75
rpoB 762296 c.2490G>C synonymous_variant 0.75
rpoB 762317 c.2511A>G synonymous_variant 0.6
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoB 762849 p.Tyr1015Asp missense_variant 0.75
rpoC 762857 c.-513C>G upstream_gene_variant 0.75
rpoB 762858 p.Thr1018Ser missense_variant 0.75
rpoC 762863 c.-507T>G upstream_gene_variant 0.6
rpoB 762878 p.Ile1024Met missense_variant 0.67
rpoB 762879 p.Met1025Leu missense_variant 0.67
rpoC 762920 c.-450C>T upstream_gene_variant 0.6
rpoC 762926 c.-444C>G upstream_gene_variant 0.56
rpoC 762929 c.-441G>C upstream_gene_variant 0.56
rpoC 762947 c.-423C>G upstream_gene_variant 0.33
rpoC 762971 c.-399G>C upstream_gene_variant 0.27
rpoC 762980 c.-390T>C upstream_gene_variant 0.3
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763053 c.-317T>C upstream_gene_variant 0.29
rpoC 763070 c.-300T>C upstream_gene_variant 0.5
rpoB 763075 p.Thr1090Ile missense_variant 0.5
rpoB 763077 p.Val1091His missense_variant 0.5
rpoC 763088 c.-282C>G upstream_gene_variant 0.5
rpoC 763094 c.-276G>C upstream_gene_variant 0.4
rpoC 763103 c.-267G>C upstream_gene_variant 0.4
rpoC 763115 c.-255T>C upstream_gene_variant 0.44
rpoC 763136 c.-234C>T upstream_gene_variant 0.5
rpoB 763137 p.Ile1111Val missense_variant 0.5
rpoC 763148 c.-222G>C upstream_gene_variant 0.25
rpoC 763468 c.99G>C synonymous_variant 0.33
rpoC 763483 c.114G>C synonymous_variant 0.67
rpoC 763486 c.117T>G synonymous_variant 0.6
rpoC 763504 c.135C>A synonymous_variant 0.73
rpoC 763507 c.138G>C synonymous_variant 0.75
rpoC 763528 c.159G>C synonymous_variant 0.8
rpoC 763531 c.162G>C synonymous_variant 0.8
rpoC 763534 c.165T>C synonymous_variant 0.86
rpoC 763537 c.168C>T synonymous_variant 0.8
rpoC 763546 c.177A>G synonymous_variant 0.8
rpoC 763550 p.Tyr61Ala missense_variant 0.8
rpoC 763570 c.201G>C synonymous_variant 0.69
rpoC 763622 p.Ala85Ser missense_variant 0.55
rpoC 763633 c.264T>C synonymous_variant 0.55
rpoC 763636 c.267T>C synonymous_variant 0.6
rpoC 763639 p.Glu90Asp missense_variant 0.64
rpoC 763642 c.273G>C synonymous_variant 0.67
rpoC 763660 c.291T>G synonymous_variant 0.75
rpoC 763663 c.294C>T synonymous_variant 0.77
rpoC 763669 c.300C>G synonymous_variant 0.82
rpoC 763696 c.327T>C synonymous_variant 0.9
rpoC 763708 c.339G>C synonymous_variant 0.86
rpoC 763714 c.345G>C synonymous_variant 0.86
rpoC 763717 c.348T>C synonymous_variant 0.86
rpoC 763732 c.363C>G synonymous_variant 0.67
rpoC 763744 c.375G>C synonymous_variant 0.67
rpoC 763751 p.Ile128Val missense_variant 0.67
rpoC 764115 p.Gly249Ala missense_variant 0.33
rpoC 764344 c.975C>T synonymous_variant 0.8
rpoC 764359 c.990C>G synonymous_variant 0.8
rpoC 764371 c.1002G>C synonymous_variant 0.8
rpoC 764377 c.1008C>G synonymous_variant 0.8
rpoC 764380 c.1011G>C synonymous_variant 0.8
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 1.0
rpoC 764404 c.1035C>T synonymous_variant 0.8
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.8
rpoC 764428 c.1059G>C synonymous_variant 0.8
rpoC 764434 c.1065A>G synonymous_variant 0.75
rpoC 764435 c.1066A>C synonymous_variant 0.75
rpoC 764441 p.Ile358Leu missense_variant 0.75
rpoC 764446 c.1077T>C synonymous_variant 0.75
rpoC 764449 c.1080G>C synonymous_variant 0.75
rpoC 764452 c.1083T>C synonymous_variant 0.75
rpoC 764458 c.1089G>C synonymous_variant 0.6
rpoC 764461 c.1092A>G synonymous_variant 0.6
rpoC 764485 c.1116G>C synonymous_variant 0.57
rpoC 764497 c.1128A>G synonymous_variant 0.5
rpoC 764498 p.Ser377Ala missense_variant 0.5
rpoC 764507 p.Ala380Ser missense_variant 0.67
rpoC 764521 c.1152T>C synonymous_variant 0.71
rpoC 764539 c.1170C>G synonymous_variant 0.75
rpoC 764542 c.1173C>G synonymous_variant 0.75
rpoC 764548 c.1179G>C synonymous_variant 0.75
rpoC 764560 c.1191T>C synonymous_variant 0.71
rpoC 764572 c.1203G>A synonymous_variant 0.71
rpoC 764575 c.1206T>C synonymous_variant 0.71
rpoC 764581 c.1212T>C synonymous_variant 0.75
rpoC 764582 p.Leu405Met missense_variant 0.78
rpoC 764611 c.1242G>T synonymous_variant 0.88
rpoC 764632 c.1263T>C synonymous_variant 0.67
rpoC 764635 c.1266C>G synonymous_variant 0.8
rpoC 764650 c.1281G>C synonymous_variant 1.0
rpoC 764665 c.1296C>G synonymous_variant 0.89
rpoC 764668 c.1299C>T synonymous_variant 0.89
rpoC 764671 c.1302G>C synonymous_variant 0.89
rpoC 764695 c.1326T>C synonymous_variant 0.75
rpoC 764701 c.1332C>G synonymous_variant 0.78
rpoC 764706 p.Leu446Gln missense_variant 0.78
rpoC 764746 c.1377G>T synonymous_variant 0.67
rpoC 764749 c.1380G>C synonymous_variant 0.67
rpoC 764758 c.1389C>G synonymous_variant 0.6
rpoC 764764 c.1395T>C synonymous_variant 0.6
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.67
rpoC 764843 p.Ala492Thr missense_variant 0.5
rpoC 764857 c.1488G>C synonymous_variant 0.5
rpoC 764858 c.1489T>C synonymous_variant 0.5
rpoC 767301 p.Gly1311Val missense_variant 0.67
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776795 c.1686C>T synonymous_variant 0.2
mmpL5 778006 p.Glu159Lys missense_variant 0.4
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800759 c.-50C>T upstream_gene_variant 0.25
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.46
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.46
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.46
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.46
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.5
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 0.2
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.33
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.38
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.94
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.46
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.48
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.97
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.54
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.17
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 0.59
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.58
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.86
rrs 1472251 n.406G>T non_coding_transcript_exon_variant 0.88
rrs 1472252 n.407G>A non_coding_transcript_exon_variant 0.49
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.49
rrs 1472256 n.411T>A non_coding_transcript_exon_variant 0.51
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.54
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 0.14
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.5
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.5
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.57
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.76
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.62
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.5
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.45
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.55
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.57
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.62
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.21
rrs 1472553 n.708C>T non_coding_transcript_exon_variant 0.24
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.62
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.65
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.25
rrs 1472572 n.727T>C non_coding_transcript_exon_variant 0.25
rrs 1472574 n.729T>C non_coding_transcript_exon_variant 0.25
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 0.26
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.69
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.27
rrs 1472583 n.738T>A non_coding_transcript_exon_variant 0.27
rrs 1472584 n.739A>G non_coding_transcript_exon_variant 0.27
rrs 1472594 n.749G>C non_coding_transcript_exon_variant 0.29
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.3
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.64
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.32
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.81
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.8
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.33
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.33
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.33
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.29
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.29
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.29
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.29
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.38
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.5
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.5
rrs 1472707 n.862A>G non_coding_transcript_exon_variant 0.5
rrs 1472714 n.869A>C non_coding_transcript_exon_variant 0.76
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.67
rrs 1472715 n.870C>G non_coding_transcript_exon_variant 0.52
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 0.56
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.87
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.87
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.86
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.88
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.4
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.81
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.81
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.81
rrs 1472973 n.1128A>C non_coding_transcript_exon_variant 0.93
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.94
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.89
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.9
rrs 1473022 n.1177G>A non_coding_transcript_exon_variant 0.79
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.78
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.78
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.75
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.75
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.8
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.79
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.78
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.79
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.77
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.81
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.89
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.85
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.85
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.9
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.9
rrs 1473139 n.1294T>C non_coding_transcript_exon_variant 0.35
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.96
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.64
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.73
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.99
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.73
rrs 1473191 n.1346C>T non_coding_transcript_exon_variant 0.69
rrs 1473198 n.1354delC non_coding_transcript_exon_variant 0.66
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.66
rrs 1473206 n.1361G>A non_coding_transcript_exon_variant 0.66
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.81
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.89
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.9
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.97
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.96
rrs 1473317 n.1472G>A non_coding_transcript_exon_variant 0.96
rrl 1473391 n.-267C>T upstream_gene_variant 0.6
rrl 1473450 n.-208C>T upstream_gene_variant 0.5
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.22
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.23
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.25
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.25
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.21
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.21
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.19
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.19
rrl 1473922 n.265A>T non_coding_transcript_exon_variant 0.17
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.17
rrl 1473924 n.267A>G non_coding_transcript_exon_variant 0.17
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.29
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 0.29
rrl 1474133 n.476T>A non_coding_transcript_exon_variant 0.56
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.6
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.6
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.73
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.78
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.8
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.86
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.86
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.86
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.86
rrl 1474186 n.529A>T non_coding_transcript_exon_variant 0.87
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.83
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.65
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.6
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.43
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.43
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.43
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.33
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.33
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.5
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.5
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.5
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.5
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.5
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.5
rrl 1474381 n.724T>A non_coding_transcript_exon_variant 0.62
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.62
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.86
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.85
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.88
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.88
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.87
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.87
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.84
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.84
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.84
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.78
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.78
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.78
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.78
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.76
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.78
rrl 1474662 n.1005C>A non_coding_transcript_exon_variant 0.85
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.89
rrl 1474688 n.1031G>T non_coding_transcript_exon_variant 0.85
rrl 1474710 n.1053T>G non_coding_transcript_exon_variant 0.8
rrl 1474711 n.1054_1055insAA non_coding_transcript_exon_variant 0.79
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.79
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.8
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.83
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.83
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.85
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.84
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.84
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.85
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.81
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.88
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.89
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.94
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.92
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.88
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.88
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.88
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.81
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.81
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.77
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.72
rrl 1474944 n.1287G>A non_coding_transcript_exon_variant 0.44
rrl 1474948 n.1291C>T non_coding_transcript_exon_variant 0.38
rrl 1475488 n.1831G>T non_coding_transcript_exon_variant 0.21
rrl 1475491 n.1834C>T non_coding_transcript_exon_variant 0.14
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.17
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.88
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.19
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.87
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.89
rrl 1475540 n.1883C>T non_coding_transcript_exon_variant 0.7
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.89
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.19
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.19
rrl 1475550 n.1893A>C non_coding_transcript_exon_variant 0.7
rrl 1475551 n.1894T>G non_coding_transcript_exon_variant 0.7
rrl 1475555 n.1898T>G non_coding_transcript_exon_variant 0.69
rrl 1475564 n.1907C>A non_coding_transcript_exon_variant 0.67
rrl 1475574 n.1917C>G non_coding_transcript_exon_variant 0.65
rrl 1475575 n.1918C>T non_coding_transcript_exon_variant 0.67
rrl 1475576 n.1919C>G non_coding_transcript_exon_variant 0.65
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.2
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.3
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.3
rrl 1475688 n.2031G>A non_coding_transcript_exon_variant 0.3
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.46
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.71
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.9
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.88
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.5
rrl 1475757 n.2101_2104delACCC non_coding_transcript_exon_variant 0.84
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.84
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.84
rrl 1475766 n.2109G>C non_coding_transcript_exon_variant 0.84
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.82
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.82
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.78
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.76
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.79
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.79
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.44
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.78
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.78
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.74
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.71
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.7
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.75
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.75
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.56
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.5
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.5
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.5
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.38
rrl 1475990 n.2333G>A non_coding_transcript_exon_variant 0.36
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.31
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.31
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.31
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.31
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.15
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.46
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.5
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.26
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.76
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.77
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.77
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.76
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.71
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.68
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.52
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.43
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.48
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.48
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.48
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.48
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.52
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.5
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.2
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.2
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.2
rrl 1476299 n.2642C>G non_coding_transcript_exon_variant 0.2
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.2
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.2
rrl 1476308 n.2651G>C non_coding_transcript_exon_variant 0.15
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.29
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.38
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.17
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.8
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.77
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.79
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.78
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.92
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.78
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.94
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.78
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.78
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.78
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.85
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.85
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.84
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.97
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.83
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.83
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.84
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.84
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.81
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.96
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.19
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.88
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.36
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.44
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.51
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.27
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.71
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.73
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.71
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.67
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.65
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.65
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.64
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.65
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.56
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.6
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.6
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.6
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.6
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.6
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.6
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.53
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.47
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.47
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.47
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.45
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.45
rrl 1476630 n.2973A>T non_coding_transcript_exon_variant 0.45
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.17
rpsA 1833653 p.Ile38Leu missense_variant 0.33
rpsA 1833661 c.120A>G synonymous_variant 0.33
rpsA 1833668 p.Ile43Val missense_variant 0.43
rpsA 1833676 c.135A>G synonymous_variant 0.6
rpsA 1833685 c.144G>C synonymous_variant 0.62
rpsA 1833694 c.153G>C synonymous_variant 0.62
rpsA 1833697 c.156C>G synonymous_variant 0.62
rpsA 1833721 c.180A>G synonymous_variant 0.5
rpsA 1833727 c.186G>C synonymous_variant 0.5
rpsA 1833733 c.192C>G synonymous_variant 0.56
rpsA 1833734 p.Ala65Ser missense_variant 0.56
rpsA 1833742 c.201A>G synonymous_variant 0.57
rpsA 1833763 c.222C>G synonymous_variant 0.5
rpsA 1833769 c.228C>G synonymous_variant 0.4
rpsA 1833770 p.Asn77Asp missense_variant 0.4
rpsA 1834040 p.Lys167Gln missense_variant 0.33
rpsA 1834043 p.Glu168Lys missense_variant 0.33
rpsA 1834046 p.Ile169Leu missense_variant 0.33
rpsA 1834054 c.513C>G synonymous_variant 0.29
rpsA 1834369 c.828C>G synonymous_variant 0.5
rpsA 1834378 c.837T>C synonymous_variant 0.57
rpsA 1834384 c.843A>G synonymous_variant 0.8
rpsA 1834395 p.Arg285Gln missense_variant 0.8
rpsA 1834398 p.His286Leu missense_variant 0.8
rpsA 1834411 c.870T>C synonymous_variant 0.86
rpsA 1834417 c.876G>C synonymous_variant 0.86
rpsA 1834418 p.Ile293Leu missense_variant 0.86
rpsA 1834423 c.882G>C synonymous_variant 0.88
rpsA 1834427 p.Ile296Val missense_variant 0.89
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.89
rpsA 1834456 c.915T>G synonymous_variant 0.89
rpsA 1834468 c.927A>G synonymous_variant 0.89
rpsA 1834480 c.939C>G synonymous_variant 1.0
rpsA 1834486 p.Glu315Asp missense_variant 0.71
rpsA 1834489 c.948T>C synonymous_variant 0.71
rpsA 1834501 c.960G>C synonymous_variant 0.57
rpsA 1834513 c.972C>G synonymous_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102621 p.Ile141Asn missense_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2156122 c.-11G>C upstream_gene_variant 0.33
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170461 p.Gly51Glu missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 0.67
ahpC 2725949 c.-244G>A upstream_gene_variant 0.5
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ribD 2986922 c.84C>A synonymous_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087176 c.357C>T synonymous_variant 0.22
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568787 c.-108T>A upstream_gene_variant 0.22
rpoA 3877848 c.660C>A synonymous_variant 0.33
rpoA 3877935 p.Lys191Arg missense_variant 0.33
rpoA 3877959 c.549C>G synonymous_variant 0.33
rpoA 3877962 c.546G>T synonymous_variant 0.29
rpoA 3877971 p.Asp179Glu missense_variant 0.25
rpoA 3877974 c.534G>C synonymous_variant 0.25
rpoA 3877981 p.Tyr176Phe missense_variant 0.25
rpoA 3877989 c.519A>G synonymous_variant 0.22
rpoA 3877995 c.513G>C synonymous_variant 0.22
rpoA 3878001 c.507A>C synonymous_variant 0.25
rpoA 3878013 c.495T>C synonymous_variant 0.33
clpC1 4039814 c.891C>G synonymous_variant 0.5
clpC1 4039817 c.888A>C synonymous_variant 0.5
clpC1 4039820 c.885T>G synonymous_variant 0.5
clpC1 4039823 c.882T>G synonymous_variant 0.5
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.5
clpC1 4039838 p.Leu289Ile missense_variant 0.6
clpC1 4039850 c.855T>C synonymous_variant 0.6
clpC1 4039865 c.840T>G synonymous_variant 0.6
clpC1 4039875 p.Asn277Arg missense_variant 0.6
clpC1 4039898 c.807C>G synonymous_variant 0.5
clpC1 4039974 p.Asp244Gly missense_variant 0.36
clpC1 4039977 p.Lys243Arg missense_variant 0.36
clpC1 4039988 c.717C>G synonymous_variant 0.36
clpC1 4039991 c.714G>C synonymous_variant 0.4
clpC1 4039994 p.Glu237Asp missense_variant 0.4
clpC1 4040001 p.His235Arg missense_variant 0.36
clpC1 4040003 p.Val234Asp missense_variant 0.36
clpC1 4040009 c.696C>G synonymous_variant 0.46
clpC1 4040015 c.690G>C synonymous_variant 0.5
clpC1 4040021 c.684A>C synonymous_variant 0.53
clpC1 4040024 c.681A>G synonymous_variant 0.53
clpC1 4040033 c.672G>C synonymous_variant 0.53
clpC1 4040063 c.642G>C synonymous_variant 0.45
clpC1 4040069 c.636G>C synonymous_variant 0.4
clpC1 4040087 c.618G>C synonymous_variant 0.5
clpC1 4040090 c.615T>C synonymous_variant 0.5
clpC1 4040108 c.597G>C synonymous_variant 0.5
embC 4240172 p.Val104Met missense_variant 1.0
embC 4241562 p.Arg567His missense_variant 1.0
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248664 c.2151G>T synonymous_variant 0.17
ubiA 4269871 c.-38G>T upstream_gene_variant 0.5
ethA 4328154 c.-681C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0