TB-Profiler

Lineage	Family	RDs	Frequency
lineage4	Euro-American	None	1.0
lineage4.9	Euro-American (H37Rv-like)	None	1.0

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
rrs	1472644	n.799C>T	non_coding_transcript_exon_variant	0.51	streptomycin	Uncertain significance	Mutation from literature
rrs	1473247	n.1402C>A	non_coding_transcript_exon_variant	0.55	amikacin	Uncertain significance	Mutation from literature
capreomycin	Uncertain significance	Mutation from literature
kanamycin	Uncertain significance	Mutation from literature
rrs	1473329	n.1484G>T	non_coding_transcript_exon_variant	0.42	amikacin	Assoc w R
capreomycin	Assoc w R
kanamycin	Assoc w R

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	0.94	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472078	n.233C>T	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472102	n.257G>A	non_coding_transcript_exon_variant	0.5	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472106	n.261G>A	non_coding_transcript_exon_variant	0.52	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	0.5	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472112	n.267C>T	non_coding_transcript_exon_variant	0.52	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472113	n.268T>C	non_coding_transcript_exon_variant	0.5	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472122	n.277G>T	non_coding_transcript_exon_variant	0.35	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472123	n.278A>T	non_coding_transcript_exon_variant	0.37	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472124	n.279C>T	non_coding_transcript_exon_variant	0.43	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472150	n.305T>A	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472155	n.310C>T	non_coding_transcript_exon_variant	0.43	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472160	n.315C>T	non_coding_transcript_exon_variant	0.38	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472172	n.327T>C	non_coding_transcript_exon_variant	0.62	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472225	n.380C>A	non_coding_transcript_exon_variant	0.31	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472251	n.406G>A	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472258	n.413A>G	non_coding_transcript_exon_variant	0.29	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472259	n.414C>A	non_coding_transcript_exon_variant	0.34	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472282	n.437T>G	non_coding_transcript_exon_variant	0.42	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472344	n.499C>T	non_coding_transcript_exon_variant	0.95	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472379	n.534T>C	non_coding_transcript_exon_variant	0.59	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472400	n.555C>T	non_coding_transcript_exon_variant	0.92	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472412	n.567A>G	non_coding_transcript_exon_variant	0.6	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472416	n.571C>T	non_coding_transcript_exon_variant	0.77	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472494	n.649A>G	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472496	n.651T>A	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472498	n.653C>T	non_coding_transcript_exon_variant	0.96	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472513	n.668T>C	non_coding_transcript_exon_variant	0.98	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472549	n.704G>A	non_coding_transcript_exon_variant	0.96	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472558	n.713G>A	non_coding_transcript_exon_variant	0.42	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472569	n.724G>A	non_coding_transcript_exon_variant	0.43	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472581	n.736A>C	non_coding_transcript_exon_variant	0.53	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472581	n.736A>T	non_coding_transcript_exon_variant	0.46	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472584	n.739A>T	non_coding_transcript_exon_variant	0.5	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472597	n.752G>A	non_coding_transcript_exon_variant	0.45	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472607	n.762G>A	non_coding_transcript_exon_variant	0.46	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472647	n.802C>T	non_coding_transcript_exon_variant	0.39	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472655	n.810G>T	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472660	n.815T>C	non_coding_transcript_exon_variant	0.96	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472673	n.828_842delTTTCCTTCCTTGGGAinsGGACATTCCACGTTT	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472690	n.845C>T	non_coding_transcript_exon_variant	0.31	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin
rrs	1472692	n.847T>C	non_coding_transcript_exon_variant	0.9	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472707	n.862A>T	non_coding_transcript_exon_variant	0.38	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472714	n.869A>G	non_coding_transcript_exon_variant	0.89	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472755	n.910G>A	non_coding_transcript_exon_variant	0.4	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472790	n.945T>C	non_coding_transcript_exon_variant	0.75	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472824	n.979T>A	non_coding_transcript_exon_variant	0.91	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472825	n.980G>A	non_coding_transcript_exon_variant	0.72	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472828	n.983T>C	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472840	n.995A>G	non_coding_transcript_exon_variant	0.77	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472875	n.1030T>C	non_coding_transcript_exon_variant	0.75	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472895	n.1050C>T	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472952	n.1107T>C	non_coding_transcript_exon_variant	0.44	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472954	n.1109T>C	non_coding_transcript_exon_variant	0.47	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472955	n.1110C>T	non_coding_transcript_exon_variant	0.43	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472956	n.1111T>C	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472957	n.1112C>T	non_coding_transcript_exon_variant	0.94	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472973	n.1128A>G	non_coding_transcript_exon_variant	0.35	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472973	n.1128A>T	non_coding_transcript_exon_variant	0.65	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472987	n.1142G>A	non_coding_transcript_exon_variant	0.47	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472989	n.1144G>A	non_coding_transcript_exon_variant	0.44	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472990	n.1145A>G	non_coding_transcript_exon_variant	0.97	kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472992	n.1147A>G	non_coding_transcript_exon_variant	0.44	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473005	n.1160C>T	non_coding_transcript_exon_variant	0.41	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473035	n.1190G>A	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473055	n.1210C>T	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473056	n.1211A>T	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473066	n.1221A>G	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473088	n.1243A>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473093	n.1248C>T	non_coding_transcript_exon_variant	0.9	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473100	n.1255G>A	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473102	n.1257C>T	non_coding_transcript_exon_variant	0.89	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473110	n.1265T>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473111	n.1266A>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473115	n.1270G>T	non_coding_transcript_exon_variant	0.66	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473121	n.1276T>C	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473145	n.1300C>T	non_coding_transcript_exon_variant	0.93	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473166	n.1321G>A	non_coding_transcript_exon_variant	0.94	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473172	n.1327T>G	non_coding_transcript_exon_variant	0.28	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473173	n.1328C>T	non_coding_transcript_exon_variant	0.32	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1473221	n.1376C>T	non_coding_transcript_exon_variant	0.4	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473252	n.1407T>C	non_coding_transcript_exon_variant	0.95	kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473259	n.1414C>T	non_coding_transcript_exon_variant	0.96	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473270	n.1425G>A	non_coding_transcript_exon_variant	0.52	kanamycin	Uncertain significance
					capreomycin
					streptomycin
					amikacin	Uncertain significance
rrs	1473276	n.1431A>C	non_coding_transcript_exon_variant	0.46	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473276	n.1431A>G	non_coding_transcript_exon_variant	0.54	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473277	n.1432G>A	non_coding_transcript_exon_variant	0.43	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1473288	n.1443_1446delCTCGinsTTTTT	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473293	n.1449delA	non_coding_transcript_exon_variant	0.42	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473300	n.1455C>T	non_coding_transcript_exon_variant	0.49	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473301	n.1456T>C	non_coding_transcript_exon_variant	0.47	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473301	n.1456T>G	non_coding_transcript_exon_variant	0.52	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473305	n.1460G>T	non_coding_transcript_exon_variant	0.48	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473316	n.1471C>T	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1474164	n.507C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474164	n.507C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474181	n.524C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474181	n.524C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474184	n.527C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474184	n.527C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	0.32	capreomycin	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	0.32	linezolid
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	0.35	capreomycin	Uncertain significance
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	0.35	linezolid	Uncertain significance
rrl	1474197	n.540C>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1474197	n.540C>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1474199	n.542G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474199	n.542G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474200	n.545delT	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474200	n.545delT	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474271	n.614A>G	non_coding_transcript_exon_variant	0.78	capreomycin
rrl	1474271	n.614A>G	non_coding_transcript_exon_variant	0.78	linezolid
rrl	1474272	n.615C>T	non_coding_transcript_exon_variant	0.78	capreomycin
rrl	1474272	n.615C>T	non_coding_transcript_exon_variant	0.78	linezolid
rrl	1474275	n.618T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474275	n.618T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474467	n.810A>G	non_coding_transcript_exon_variant	0.81	capreomycin
rrl	1474467	n.810A>G	non_coding_transcript_exon_variant	0.81	linezolid
rrl	1474488	n.831G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474488	n.831G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474495	n.838G>A	non_coding_transcript_exon_variant	0.68	capreomycin
rrl	1474495	n.838G>A	non_coding_transcript_exon_variant	0.68	linezolid
rrl	1474496	n.839C>A	non_coding_transcript_exon_variant	0.75	capreomycin	Uncertain significance
rrl	1474496	n.839C>A	non_coding_transcript_exon_variant	0.75	linezolid	Uncertain significance
rrl	1474506	n.849C>G	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1474506	n.849C>G	non_coding_transcript_exon_variant	0.58	linezolid	Uncertain significance
rrl	1474507	n.850G>T	non_coding_transcript_exon_variant	0.5	capreomycin	Uncertain significance
rrl	1474507	n.850G>T	non_coding_transcript_exon_variant	0.5	linezolid	Uncertain significance
rrl	1474508	n.851C>T	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1474508	n.851C>T	non_coding_transcript_exon_variant	0.68	linezolid	Uncertain significance
rrl	1474516	n.859C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474516	n.859C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474527	n.870T>C	non_coding_transcript_exon_variant	0.54	capreomycin
rrl	1474527	n.870T>C	non_coding_transcript_exon_variant	0.54	linezolid
rrl	1474528	n.871T>A	non_coding_transcript_exon_variant	0.35	capreomycin
rrl	1474528	n.871T>A	non_coding_transcript_exon_variant	0.35	linezolid
rrl	1474529	n.872A>C	non_coding_transcript_exon_variant	0.45	capreomycin
rrl	1474529	n.872A>C	non_coding_transcript_exon_variant	0.45	linezolid
rrl	1474529	n.872A>G	non_coding_transcript_exon_variant	0.34	capreomycin
rrl	1474529	n.872A>G	non_coding_transcript_exon_variant	0.34	linezolid
rrl	1474530	n.873G>A	non_coding_transcript_exon_variant	0.45	capreomycin
rrl	1474530	n.873G>A	non_coding_transcript_exon_variant	0.45	linezolid
rrl	1474537	n.880G>A	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1474537	n.880G>A	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1474539	n.882C>T	non_coding_transcript_exon_variant	0.41	capreomycin
rrl	1474539	n.882C>T	non_coding_transcript_exon_variant	0.41	linezolid
rrl	1474540	n.883T>C	non_coding_transcript_exon_variant	0.28	capreomycin
rrl	1474540	n.883T>C	non_coding_transcript_exon_variant	0.28	linezolid
rrl	1474540	n.883T>G	non_coding_transcript_exon_variant	0.41	capreomycin
rrl	1474540	n.883T>G	non_coding_transcript_exon_variant	0.41	linezolid
rrl	1474542	n.885A>G	non_coding_transcript_exon_variant	0.33	capreomycin
rrl	1474542	n.885A>G	non_coding_transcript_exon_variant	0.33	linezolid
rrl	1474551	n.894G>A	non_coding_transcript_exon_variant	0.3	capreomycin
rrl	1474551	n.894G>A	non_coding_transcript_exon_variant	0.3	linezolid
rrl	1474558	n.901G>A	non_coding_transcript_exon_variant	0.31	capreomycin	Uncertain significance
rrl	1474558	n.901G>A	non_coding_transcript_exon_variant	0.31	linezolid
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.52	capreomycin	Uncertain significance
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.52	linezolid	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.3	capreomycin	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.3	linezolid	Uncertain significance
rrl	1474634	n.977T>C	non_coding_transcript_exon_variant	0.64	capreomycin
rrl	1474634	n.977T>C	non_coding_transcript_exon_variant	0.64	linezolid
rrl	1474636	n.979_983delACCGCinsCTGGT	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474636	n.979_983delACCGCinsCTGGT	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474674	n.1017_1018delACinsG	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474674	n.1017_1018delACinsG	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474709	n.1052G>A	non_coding_transcript_exon_variant	0.75	capreomycin
rrl	1474709	n.1052G>A	non_coding_transcript_exon_variant	0.75	linezolid
rrl	1474711	n.1054_1060delGGTGTAAinsTAGGTGT	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474711	n.1054_1060delGGTGTAAinsTAGGTGT	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474734	n.1077G>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474734	n.1077G>T	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474749	n.1092C>T	non_coding_transcript_exon_variant	0.73	capreomycin	Uncertain significance
rrl	1474749	n.1092C>T	non_coding_transcript_exon_variant	0.73	linezolid	Uncertain significance
rrl	1474753	n.1097delC	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474753	n.1097delC	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474779	n.1122G>A	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1474779	n.1122G>A	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1474780	n.1123C>T	non_coding_transcript_exon_variant	0.66	capreomycin	Uncertain significance
rrl	1474780	n.1123C>T	non_coding_transcript_exon_variant	0.66	linezolid	Uncertain significance
rrl	1474782	n.1125G>A	non_coding_transcript_exon_variant	0.72	capreomycin	Not assoc w R
rrl	1474782	n.1125G>A	non_coding_transcript_exon_variant	0.72	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474802	n.1145T>C	non_coding_transcript_exon_variant	0.6	capreomycin	Uncertain significance
rrl	1474802	n.1145T>C	non_coding_transcript_exon_variant	0.6	linezolid	Uncertain significance
rrl	1474823	n.1166C>G	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1474823	n.1166C>G	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1474831	n.1174A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474831	n.1174A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474832	n.1175A>T	non_coding_transcript_exon_variant	0.57	capreomycin	Uncertain significance
rrl	1474832	n.1175A>T	non_coding_transcript_exon_variant	0.57	linezolid	Uncertain significance
rrl	1474864	n.1207C>T	non_coding_transcript_exon_variant	0.67	capreomycin	Not assoc w R
rrl	1474864	n.1207C>T	non_coding_transcript_exon_variant	0.67	linezolid	Uncertain significance
rrl	1474883	n.1226T>C	non_coding_transcript_exon_variant	0.34	capreomycin
rrl	1474883	n.1226T>C	non_coding_transcript_exon_variant	0.34	linezolid
rrl	1474901	n.1244A>G	non_coding_transcript_exon_variant	0.38	capreomycin
rrl	1474901	n.1244A>G	non_coding_transcript_exon_variant	0.38	linezolid
rrl	1474904	n.1247G>C	non_coding_transcript_exon_variant	0.89	capreomycin	Uncertain significance
rrl	1474904	n.1247G>C	non_coding_transcript_exon_variant	0.89	linezolid	Uncertain significance
rrl	1474913	n.1256T>C	non_coding_transcript_exon_variant	0.56	capreomycin	Uncertain significance
rrl	1474913	n.1256T>C	non_coding_transcript_exon_variant	0.56	linezolid	Uncertain significance
rrl	1474932	n.1275C>T	non_coding_transcript_exon_variant	0.4	capreomycin	Uncertain significance
rrl	1474932	n.1275C>T	non_coding_transcript_exon_variant	0.4	linezolid	Uncertain significance
rrl	1475673	n.2016T>C	non_coding_transcript_exon_variant	0.8	capreomycin	Uncertain significance
rrl	1475673	n.2016T>C	non_coding_transcript_exon_variant	0.8	linezolid	Uncertain significance
rrl	1475686	n.2029C>G	non_coding_transcript_exon_variant	0.44	capreomycin
rrl	1475686	n.2029C>G	non_coding_transcript_exon_variant	0.44	linezolid
rrl	1475696	n.2039T>C	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1475696	n.2039T>C	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1475699	n.2042C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475699	n.2042C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475703	n.2046A>G	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1475703	n.2046A>G	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1475715	n.2058G>C	non_coding_transcript_exon_variant	0.42	capreomycin
rrl	1475715	n.2058G>C	non_coding_transcript_exon_variant	0.42	linezolid
rrl	1475722	n.2065G>T	non_coding_transcript_exon_variant	0.42	capreomycin
rrl	1475722	n.2065G>T	non_coding_transcript_exon_variant	0.42	linezolid
rrl	1475751	n.2094C>A	non_coding_transcript_exon_variant	0.53	capreomycin
rrl	1475751	n.2094C>A	non_coding_transcript_exon_variant	0.53	linezolid
rrl	1475751	n.2094C>T	non_coding_transcript_exon_variant	0.46	capreomycin
rrl	1475751	n.2094C>T	non_coding_transcript_exon_variant	0.46	linezolid
rrl	1475752	n.2095C>T	non_coding_transcript_exon_variant	0.42	capreomycin	Uncertain significance
rrl	1475752	n.2095C>T	non_coding_transcript_exon_variant	0.42	linezolid	Uncertain significance
rrl	1475753	n.2096C>G	non_coding_transcript_exon_variant	0.51	capreomycin	Uncertain significance
rrl	1475753	n.2096C>G	non_coding_transcript_exon_variant	0.51	linezolid
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.45	capreomycin
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.45	linezolid
rrl	1475758	n.2101_2108delACCCGCAAinsGCCTTTTTT	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475758	n.2101_2108delACCCGCAAinsGCCTTTTTT	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475769	n.2112T>C	non_coding_transcript_exon_variant	0.43	capreomycin
rrl	1475769	n.2112T>C	non_coding_transcript_exon_variant	0.43	linezolid
rrl	1475775	n.2118G>T	non_coding_transcript_exon_variant	0.44	capreomycin	Uncertain significance
rrl	1475775	n.2118G>T	non_coding_transcript_exon_variant	0.44	linezolid	Uncertain significance
rrl	1475777	n.2120A>T	non_coding_transcript_exon_variant	0.55	capreomycin
rrl	1475777	n.2120A>T	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1475869	n.2212C>A	non_coding_transcript_exon_variant	0.34	capreomycin
rrl	1475869	n.2212C>A	non_coding_transcript_exon_variant	0.34	linezolid
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	0.44	capreomycin
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	0.44	linezolid
rrl	1475883	n.2226A>C	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1475883	n.2226A>C	non_coding_transcript_exon_variant	0.65	linezolid
rrl	1475883	n.2226A>T	non_coding_transcript_exon_variant	0.35	capreomycin	Uncertain significance
rrl	1475883	n.2226A>T	non_coding_transcript_exon_variant	0.35	linezolid	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.63	capreomycin	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.63	linezolid	Uncertain significance
rrl	1475892	n.2235A>G	non_coding_transcript_exon_variant	0.46	capreomycin
rrl	1475892	n.2235A>G	non_coding_transcript_exon_variant	0.46	linezolid
rrl	1475896	n.2239A>G	non_coding_transcript_exon_variant	0.49	capreomycin
rrl	1475896	n.2239A>G	non_coding_transcript_exon_variant	0.49	linezolid
rrl	1475897	n.2240T>C	non_coding_transcript_exon_variant	0.35	capreomycin	Uncertain significance
rrl	1475897	n.2240T>C	non_coding_transcript_exon_variant	0.35	linezolid	Uncertain significance
rrl	1475898	n.2241A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475898	n.2241A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475899	n.2242G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475899	n.2242G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475906	n.2249C>T	non_coding_transcript_exon_variant	0.39	capreomycin	Uncertain significance
rrl	1475906	n.2249C>T	non_coding_transcript_exon_variant	0.39	linezolid	Uncertain significance
rrl	1475916	n.2259C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475916	n.2259C>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475937	n.2280A>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475937	n.2280A>T	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475943	n.2286G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475943	n.2286G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475945	n.2288C>A	non_coding_transcript_exon_variant	0.66	capreomycin
rrl	1475945	n.2288C>A	non_coding_transcript_exon_variant	0.66	linezolid
rrl	1475952	n.2295A>G	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1475952	n.2295A>G	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1475963	n.2306G>T	non_coding_transcript_exon_variant	0.35	capreomycin
rrl	1475963	n.2306G>T	non_coding_transcript_exon_variant	0.35	linezolid
rrl	1475970	n.2313C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475970	n.2313C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476130	n.2473G>A	non_coding_transcript_exon_variant	0.72	capreomycin	Uncertain significance
rrl	1476130	n.2473G>A	non_coding_transcript_exon_variant	0.72	linezolid	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.92	linezolid	Uncertain significance
rrl	1476164	n.2507A>G	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1476164	n.2507A>G	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1476194	n.2537A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1476194	n.2537A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476200	n.2543A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476200	n.2543A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476201	n.2544C>T	non_coding_transcript_exon_variant	0.97	capreomycin	Not assoc w R
rrl	1476201	n.2544C>T	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.78	capreomycin	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.78	linezolid	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.8	capreomycin	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.8	linezolid	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476245	n.2588C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1476245	n.2588C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1476252	n.2595T>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476252	n.2595T>G	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1476253	n.2596A>G	non_coding_transcript_exon_variant	0.9	capreomycin
rrl	1476253	n.2596A>G	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476256	n.2599A>G	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476256	n.2599A>G	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.77	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.77	linezolid	Uncertain significance
rrl	1476294	n.2637A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476294	n.2637A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476295	n.2638C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476295	n.2638C>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476296	n.2639C>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476296	n.2639C>T	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1476297	n.2640C>A	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476297	n.2640C>A	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1476299	n.2642C>G	non_coding_transcript_exon_variant	0.57	capreomycin
rrl	1476299	n.2642C>G	non_coding_transcript_exon_variant	0.57	linezolid
rrl	1476300	n.2643G>T	non_coding_transcript_exon_variant	0.57	capreomycin
rrl	1476300	n.2643G>T	non_coding_transcript_exon_variant	0.57	linezolid
rrl	1476301	n.2644A>T	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1476301	n.2644A>T	non_coding_transcript_exon_variant	0.58	linezolid	Uncertain significance
rrl	1476308	n.2651G>C	non_coding_transcript_exon_variant	0.59	capreomycin
rrl	1476308	n.2651G>C	non_coding_transcript_exon_variant	0.59	linezolid
rrl	1476311	n.2654G>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476311	n.2654G>C	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476312	n.2655T>C	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476312	n.2655T>C	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.3	capreomycin	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.3	linezolid	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.32	capreomycin	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.32	linezolid	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.47	capreomycin	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.47	linezolid	Uncertain significance
rrl	1476359	n.2702C>G	non_coding_transcript_exon_variant	0.52	capreomycin	Uncertain significance
rrl	1476359	n.2702C>G	non_coding_transcript_exon_variant	0.52	linezolid	Uncertain significance
rrl	1476369	n.2712C>T	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1476369	n.2712C>T	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.28	capreomycin	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.28	linezolid	Uncertain significance
rrl	1476381	n.2724G>C	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1476381	n.2724G>C	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.51	capreomycin	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.51	linezolid	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.33	capreomycin	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.33	linezolid	Uncertain significance
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Not assoc w R
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1476429	n.2772A>C	non_coding_transcript_exon_variant	0.6	capreomycin	Uncertain significance
rrl	1476429	n.2772A>C	non_coding_transcript_exon_variant	0.6	linezolid	Uncertain significance
rrl	1476466	n.2809C>T	non_coding_transcript_exon_variant	0.61	capreomycin	Not assoc w R
rrl	1476466	n.2809C>T	non_coding_transcript_exon_variant	0.61	linezolid	Uncertain significance
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.96	capreomycin	Not assoc w R
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	0.85	capreomycin	Not assoc w R
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	0.85	linezolid	Uncertain significance
rrl	1476513	n.2856G>T	non_coding_transcript_exon_variant	0.33	capreomycin
rrl	1476513	n.2856G>T	non_coding_transcript_exon_variant	0.33	linezolid
rrl	1476515	n.2858C>T	non_coding_transcript_exon_variant	0.74	capreomycin	Uncertain significance
rrl	1476515	n.2858C>T	non_coding_transcript_exon_variant	0.74	linezolid
rrl	1476519	n.2862C>G	non_coding_transcript_exon_variant	0.24	capreomycin	Uncertain significance
rrl	1476519	n.2862C>G	non_coding_transcript_exon_variant	0.24	linezolid	Uncertain significance
rrl	1476523	n.2866T>C	non_coding_transcript_exon_variant	0.29	capreomycin	Uncertain significance
rrl	1476523	n.2866T>C	non_coding_transcript_exon_variant	0.29	linezolid	Uncertain significance
rrl	1476524	n.2867C>A	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476524	n.2867C>A	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1476525	n.2868A>G	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476525	n.2868A>G	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1476530	n.2873C>T	non_coding_transcript_exon_variant	0.81	capreomycin	Uncertain significance
rrl	1476530	n.2873C>T	non_coding_transcript_exon_variant	0.81	linezolid	Uncertain significance
rrl	1476536	n.2879G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476536	n.2879G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476539	n.2882_2883delACinsGG	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476539	n.2882_2883delACinsGG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476547	n.2890C>T	non_coding_transcript_exon_variant	0.54	capreomycin	Uncertain significance
rrl	1476547	n.2890C>T	non_coding_transcript_exon_variant	0.54	linezolid	Uncertain significance
rrl	1476567	n.2910C>T	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1476567	n.2910C>T	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.98	capreomycin	Not assoc w R
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476585	n.2928A>G	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1476585	n.2928A>G	non_coding_transcript_exon_variant	0.87	linezolid	Uncertain significance
rrl	1476600	n.2943A>C	non_coding_transcript_exon_variant	0.31	capreomycin
rrl	1476600	n.2943A>C	non_coding_transcript_exon_variant	0.31	linezolid

Drug	Resistance	Supporting mutations	WHO confidence	Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin	rrs	n.799C>T	Uncertain significance	Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin	rrs	n.1402C>A	Uncertain significance	Mutation from literature
amikacin	rrs	n.1484G>T	Assoc w R
capreomycin	rrs	n.1402C>A	Uncertain significance	Mutation from literature
capreomycin	rrs	n.1484G>T	Assoc w R
kanamycin	rrs	n.1402C>A	Uncertain significance	Mutation from literature
kanamycin	rrs	n.1484G>T	Assoc w R
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid

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