TB-Profiler

Lineage	Family	RDs	Frequency
lineage4	Euro-American	None	1.0
lineage4.9	Euro-American (H37Rv-like)	None	1.0

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
rrs	1472733	n.888G>A	non_coding_transcript_exon_variant	0.69	streptomycin	Uncertain significance	Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
rpoC	764626	c.1257C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764632	c.1263T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764647	c.1278C>T	synonymous_variant	1.0	rifampicin
rpoC	764650	c.1281G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764653	c.1284G>C	synonymous_variant	1.0	rifampicin
rpoC	764662	c.1293G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rrs	1472150	n.305T>A	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472155	n.310C>T	non_coding_transcript_exon_variant	0.65	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472160	n.315C>T	non_coding_transcript_exon_variant	0.72	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472225	n.380C>A	non_coding_transcript_exon_variant	0.74	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Uncertain significance
rrs	1472338	n.493A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472344	n.499C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472379	n.534T>C	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472400	n.555C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472412	n.567A>G	non_coding_transcript_exon_variant	0.91	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472416	n.571C>T	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472422	n.577T>C	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Uncertain significance
rrs	1472427	n.582T>G	non_coding_transcript_exon_variant	0.97	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472435	n.590T>C	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472436	n.591G>T	non_coding_transcript_exon_variant	0.97	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472437	n.592T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472438	n.593T>C	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472448	n.603T>C	non_coding_transcript_exon_variant	0.8	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472462	n.617T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472464	n.619A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472473	n.628G>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472474	n.629C>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472476	n.631A>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472484	n.639A>T	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472489	n.644A>T	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472494	n.649A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472496	n.651T>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472498	n.653C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472507	n.662C>G	non_coding_transcript_exon_variant	0.42	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472513	n.668T>C	non_coding_transcript_exon_variant	0.54	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472517	n.672T>A	non_coding_transcript_exon_variant	0.4	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472518	n.673G>T	non_coding_transcript_exon_variant	0.41	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472530	n.685G>A	non_coding_transcript_exon_variant	0.56	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472537	n.692C>T	non_coding_transcript_exon_variant	0.61	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472544	n.699C>A	non_coding_transcript_exon_variant	0.6	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472545	n.700A>T	non_coding_transcript_exon_variant	0.54	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472549	n.704G>A	non_coding_transcript_exon_variant	0.34	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472566	n.721G>A	non_coding_transcript_exon_variant	0.39	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472571	n.726G>C	non_coding_transcript_exon_variant	0.65	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472579	n.734G>C	non_coding_transcript_exon_variant	0.44	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472581	n.736A>T	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472598	n.753A>C	non_coding_transcript_exon_variant	0.72	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472599	n.754G>T	non_coding_transcript_exon_variant	0.66	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472616	n.771G>A	non_coding_transcript_exon_variant	0.72	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472655	n.810G>A	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472658	n.813G>A	non_coding_transcript_exon_variant	0.75	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472661	n.816A>G	non_coding_transcript_exon_variant	0.69	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472670	n.825_838delGGGTTTCCTTCCTTinsTAGACCCTTTCCG	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472687	n.842_844delATCinsTTT	non_coding_transcript_exon_variant	0.52	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472687	n.842A>T	non_coding_transcript_exon_variant	0.41	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472690	n.845C>A	non_coding_transcript_exon_variant	0.95	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472697	n.852T>C	non_coding_transcript_exon_variant	0.45	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472713	n.868T>C	non_coding_transcript_exon_variant	0.67	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472714	n.869A>G	non_coding_transcript_exon_variant	0.31	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472716	n.871C>T	non_coding_transcript_exon_variant	0.73	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472742	n.897C>T	non_coding_transcript_exon_variant	0.68	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472744	n.899A>G	non_coding_transcript_exon_variant	0.68	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472781	n.936C>T	non_coding_transcript_exon_variant	0.64	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472790	n.945T>C	non_coding_transcript_exon_variant	0.37	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472793	n.948A>T	non_coding_transcript_exon_variant	0.61	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472803	n.958T>A	non_coding_transcript_exon_variant	0.58	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472824	n.979T>A	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472825	n.980G>A	non_coding_transcript_exon_variant	0.62	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472828	n.983T>C	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472836	n.991G>C	non_coding_transcript_exon_variant	0.33	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472838	n.993_998delACAGGAinsCTCTGAC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472846	n.1002delG	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472850	n.1005_1006insGC	non_coding_transcript_exon_variant	0.5	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472857	n.1012_1021delAGGCGTTCCCinsG	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472868	n.1023T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472873	n.1028C>A	non_coding_transcript_exon_variant	0.35	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472874	n.1029_1030delCTinsATTTAGTTGGTC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472880	n.1035_1036insA	non_coding_transcript_exon_variant	0.35	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472895	n.1050C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472954	n.1109T>C	non_coding_transcript_exon_variant	0.71	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472956	n.1111T>C	non_coding_transcript_exon_variant	0.89	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472957	n.1112C>T	non_coding_transcript_exon_variant	0.92	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472973	n.1128A>G	non_coding_transcript_exon_variant	0.94	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472990	n.1145A>G	non_coding_transcript_exon_variant	0.93	streptomycin	Uncertain significance
					kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472992	n.1147A>G	non_coding_transcript_exon_variant	0.71	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473005	n.1160C>T	non_coding_transcript_exon_variant	0.76	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473035	n.1190G>A	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473055	n.1210C>T	non_coding_transcript_exon_variant	0.96	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473056	n.1211A>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473066	n.1221A>G	non_coding_transcript_exon_variant	0.85	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473080	n.1235C>T	non_coding_transcript_exon_variant	0.78	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473081	n.1236C>T	non_coding_transcript_exon_variant	0.83	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473088	n.1243A>G	non_coding_transcript_exon_variant	0.88	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473093	n.1248C>T	non_coding_transcript_exon_variant	0.87	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473100	n.1255G>A	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473101	n.1256C>T	non_coding_transcript_exon_variant	0.53	streptomycin
					kanamycin	Uncertain significance
					capreomycin
					amikacin	Uncertain significance
rrs	1473102	n.1257C>T	non_coding_transcript_exon_variant	0.41	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	0.89	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473110	n.1265T>G	non_coding_transcript_exon_variant	0.89	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473111	n.1266A>G	non_coding_transcript_exon_variant	0.88	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473121	n.1276T>C	non_coding_transcript_exon_variant	0.98	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1473123	n.1278A>T	non_coding_transcript_exon_variant	0.9	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473130	n.1285G>A	non_coding_transcript_exon_variant	0.88	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473145	n.1300C>T	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473166	n.1321G>A	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473172	n.1327T>G	non_coding_transcript_exon_variant	0.8	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473173	n.1328C>T	non_coding_transcript_exon_variant	0.74	streptomycin	Not assoc w R
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1473221	n.1376C>T	non_coding_transcript_exon_variant	0.71	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473252	n.1407T>C	non_coding_transcript_exon_variant	0.98	streptomycin	Uncertain significance
					kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1473259	n.1414C>T	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473276	n.1431A>C	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473277	n.1432G>A	non_coding_transcript_exon_variant	0.72	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473301	n.1456T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473316	n.1471C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474275	n.618T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474275	n.618T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474348	n.691C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474348	n.691C>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1474351	n.694G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474351	n.694G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474354	n.697C>T	non_coding_transcript_exon_variant	0.9	capreomycin
rrl	1474354	n.697C>T	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474542	n.885A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474542	n.885A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.56	capreomycin	Uncertain significance
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.56	linezolid	Uncertain significance
rrl	1474634	n.977T>C	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1474634	n.977T>C	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1474636	n.979A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474636	n.979A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474640	n.983C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1474640	n.983C>T	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1474674	n.1017_1018delACinsG	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474674	n.1017_1018delACinsG	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474709	n.1052G>A	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474709	n.1052G>A	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474734	n.1077G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474734	n.1077G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474749	n.1092C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474749	n.1092C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474753	n.1097delC	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474753	n.1097delC	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474779	n.1122G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474779	n.1122G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474780	n.1123C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474780	n.1123C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474782	n.1125G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1474782	n.1125G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474801	n.1144G>A	non_coding_transcript_exon_variant	0.5	capreomycin	Uncertain significance
rrl	1474801	n.1144G>A	non_coding_transcript_exon_variant	0.5	linezolid	Uncertain significance
rrl	1474802	n.1145T>C	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1474802	n.1145T>C	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1474823	n.1166C>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474823	n.1166C>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474831	n.1174A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474831	n.1174A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474832	n.1175A>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1474832	n.1175A>T	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1474864	n.1207C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1474864	n.1207C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474901	n.1244A>G	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1474901	n.1244A>G	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1474904	n.1247G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474904	n.1247G>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474913	n.1256T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1474913	n.1256T>C	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1474933	n.1276A>G	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474933	n.1276A>G	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1474934	n.1277C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474934	n.1277C>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1475696	n.2039T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475696	n.2039T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475699	n.2042C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475699	n.2042C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475703	n.2046A>G	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1475703	n.2046A>G	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1475715	n.2058G>C	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1475715	n.2058G>C	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1475751	n.2094C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475751	n.2094C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.43	capreomycin
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.43	linezolid
rrl	1475777	n.2120A>T	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475777	n.2120A>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475883	n.2226A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475883	n.2226A>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1475896	n.2239A>G	non_coding_transcript_exon_variant	0.61	capreomycin
rrl	1475896	n.2239A>G	non_coding_transcript_exon_variant	0.61	linezolid
rrl	1475897	n.2240T>C	non_coding_transcript_exon_variant	0.31	capreomycin	Uncertain significance
rrl	1475897	n.2240T>C	non_coding_transcript_exon_variant	0.31	linezolid	Uncertain significance
rrl	1475898	n.2241A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475898	n.2241A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475899	n.2242G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475899	n.2242G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475906	n.2249C>T	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1475906	n.2249C>T	non_coding_transcript_exon_variant	0.92	linezolid	Uncertain significance
rrl	1475916	n.2259C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475916	n.2259C>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475937	n.2280A>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475937	n.2280A>T	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475943	n.2286G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475943	n.2286G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475945	n.2288C>A	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1475945	n.2288C>A	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475952	n.2295A>G	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475952	n.2295A>G	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1475970	n.2313C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475970	n.2313C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475975	n.2318C>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475975	n.2318C>T	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475977	n.2320A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475977	n.2320A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475995	n.2338G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475995	n.2338G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475997	n.2340A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475997	n.2340A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475998	n.2341C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475998	n.2341C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476000	n.2343G>A	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1476000	n.2343G>A	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1476001	n.2344T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476001	n.2344T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.75	capreomycin	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.75	linezolid	Uncertain significance
rrl	1476135	n.2478T>C	non_coding_transcript_exon_variant	0.43	capreomycin	Uncertain significance
rrl	1476135	n.2478T>C	non_coding_transcript_exon_variant	0.43	linezolid	Uncertain significance
rrl	1476141	n.2484A>G	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1476141	n.2484A>G	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1476153	n.2496T>C	non_coding_transcript_exon_variant	0.54	capreomycin	Uncertain significance
rrl	1476153	n.2496T>C	non_coding_transcript_exon_variant	0.54	linezolid	Uncertain significance
rrl	1476164	n.2507A>G	non_coding_transcript_exon_variant	0.3	capreomycin	Uncertain significance
rrl	1476164	n.2507A>G	non_coding_transcript_exon_variant	0.3	linezolid	Uncertain significance
rrl	1476165	n.2508T>G	non_coding_transcript_exon_variant	0.42	capreomycin	Not assoc w R
rrl	1476165	n.2508T>G	non_coding_transcript_exon_variant	0.42	linezolid	Uncertain significance
rrl	1476179	n.2522C>T	non_coding_transcript_exon_variant	0.33	capreomycin
rrl	1476179	n.2522C>T	non_coding_transcript_exon_variant	0.33	linezolid
rrl	1476194	n.2537A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476194	n.2537A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476195	n.2538C>A	non_coding_transcript_exon_variant	0.5	capreomycin	Uncertain significance
rrl	1476195	n.2538C>A	non_coding_transcript_exon_variant	0.5	linezolid	Uncertain significance
rrl	1476196	n.2539C>A	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1476196	n.2539C>A	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1476200	n.2543A>T	non_coding_transcript_exon_variant	0.84	capreomycin	Not assoc w R
rrl	1476200	n.2543A>T	non_coding_transcript_exon_variant	0.84	linezolid	Uncertain significance
rrl	1476201	n.2544C>T	non_coding_transcript_exon_variant	0.84	capreomycin	Not assoc w R
rrl	1476201	n.2544C>T	non_coding_transcript_exon_variant	0.84	linezolid	Uncertain significance
rrl	1476204	n.2547C>A	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1476204	n.2547C>A	non_coding_transcript_exon_variant	0.85	linezolid	Uncertain significance
rrl	1476215	n.2558C>A	non_coding_transcript_exon_variant	0.62	capreomycin	Uncertain significance
rrl	1476215	n.2558C>A	non_coding_transcript_exon_variant	0.62	linezolid	Uncertain significance
rrl	1476225	n.2568T>G	non_coding_transcript_exon_variant	0.74	capreomycin	Uncertain significance
rrl	1476225	n.2568T>G	non_coding_transcript_exon_variant	0.74	linezolid	Uncertain significance
rrl	1476227	n.2570C>T	non_coding_transcript_exon_variant	0.64	capreomycin
rrl	1476227	n.2570C>T	non_coding_transcript_exon_variant	0.64	linezolid	Uncertain significance
rrl	1476229	n.2572C>T	non_coding_transcript_exon_variant	0.63	capreomycin	Uncertain significance
rrl	1476229	n.2572C>T	non_coding_transcript_exon_variant	0.63	linezolid
rrl	1476250	n.2593C>G	non_coding_transcript_exon_variant	0.54	capreomycin	Uncertain significance
rrl	1476250	n.2593C>G	non_coding_transcript_exon_variant	0.54	linezolid	Uncertain significance
rrl	1476251	n.2594T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476251	n.2594T>C	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476257	n.2600G>C	non_coding_transcript_exon_variant	0.53	capreomycin	Uncertain significance
rrl	1476257	n.2600G>C	non_coding_transcript_exon_variant	0.53	linezolid	Uncertain significance
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476280	n.2623A>C	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1476280	n.2623A>C	non_coding_transcript_exon_variant	0.87	linezolid	Uncertain significance
rrl	1476311	n.2654G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476311	n.2654G>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476312	n.2655T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476312	n.2655T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476313	n.2656G>A	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1476313	n.2656G>A	non_coding_transcript_exon_variant	0.84	linezolid	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.85	linezolid	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.78	capreomycin	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.78	linezolid	Uncertain significance
rrl	1476353	n.2696G>T	non_coding_transcript_exon_variant	0.77	capreomycin	Uncertain significance
rrl	1476353	n.2696G>T	non_coding_transcript_exon_variant	0.77	linezolid	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.83	linezolid	Uncertain significance
rrl	1476369	n.2712C>T	non_coding_transcript_exon_variant	0.74	capreomycin	Uncertain significance
rrl	1476369	n.2712C>T	non_coding_transcript_exon_variant	0.74	linezolid	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.76	capreomycin	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.76	linezolid	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.8	capreomycin	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.8	linezolid	Uncertain significance
rrl	1476425	n.2768G>T	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1476425	n.2768G>T	non_coding_transcript_exon_variant	0.68	linezolid	Uncertain significance
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476429	n.2772A>C	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476429	n.2772A>C	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1476466	n.2809C>T	non_coding_transcript_exon_variant	0.66	capreomycin	Not assoc w R
rrl	1476466	n.2809C>T	non_coding_transcript_exon_variant	0.66	linezolid	Uncertain significance
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476513	n.2856G>T	non_coding_transcript_exon_variant	0.47	capreomycin
rrl	1476513	n.2856G>T	non_coding_transcript_exon_variant	0.47	linezolid
rrl	1476514	n.2857C>T	non_coding_transcript_exon_variant	0.42	capreomycin	Uncertain significance
rrl	1476514	n.2857C>T	non_coding_transcript_exon_variant	0.42	linezolid	Uncertain significance
rrl	1476515	n.2858C>T	non_coding_transcript_exon_variant	0.51	capreomycin	Uncertain significance
rrl	1476515	n.2858C>T	non_coding_transcript_exon_variant	0.51	linezolid
rrl	1476517	n.2860C>T	non_coding_transcript_exon_variant	0.54	capreomycin	Uncertain significance
rrl	1476517	n.2860C>T	non_coding_transcript_exon_variant	0.54	linezolid
rrl	1476519	n.2862C>G	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1476519	n.2862C>G	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1476523	n.2866T>C	non_coding_transcript_exon_variant	0.53	capreomycin	Uncertain significance
rrl	1476523	n.2866T>C	non_coding_transcript_exon_variant	0.53	linezolid	Uncertain significance
rrl	1476524	n.2867C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476524	n.2867C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476525	n.2868A>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476525	n.2868A>G	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1476530	n.2873C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476530	n.2873C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476536	n.2879G>A	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1476536	n.2879G>A	non_coding_transcript_exon_variant	0.83	linezolid	Uncertain significance
rrl	1476537	n.2880A>G	non_coding_transcript_exon_variant	0.41	capreomycin	Uncertain significance
rrl	1476537	n.2880A>G	non_coding_transcript_exon_variant	0.41	linezolid	Uncertain significance
rrl	1476538	n.2881A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476538	n.2881A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476539	n.2882A>G	non_coding_transcript_exon_variant	0.59	capreomycin	Uncertain significance
rrl	1476539	n.2882A>G	non_coding_transcript_exon_variant	0.59	linezolid	Uncertain significance
rrl	1476540	n.2883C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476540	n.2883C>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476542	n.2885T>C	non_coding_transcript_exon_variant	0.59	capreomycin
rrl	1476542	n.2885T>C	non_coding_transcript_exon_variant	0.59	linezolid
rrl	1476547	n.2890C>T	non_coding_transcript_exon_variant	0.41	capreomycin	Uncertain significance
rrl	1476547	n.2890C>T	non_coding_transcript_exon_variant	0.41	linezolid	Uncertain significance
rrl	1476567	n.2910C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476567	n.2910C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.86	capreomycin	Not assoc w R
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1476585	n.2928A>G	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1476585	n.2928A>G	non_coding_transcript_exon_variant	0.68	linezolid	Uncertain significance
rrl	1476594	n.2937C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476594	n.2937C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476603	n.2946G>T	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1476603	n.2946G>T	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1476607	n.2950C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476607	n.2950C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	0.86	capreomycin	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1476614	n.2957A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476614	n.2957A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476619	n.2962C>T	non_coding_transcript_exon_variant	0.88	capreomycin	Not assoc w R
rrl	1476619	n.2962C>T	non_coding_transcript_exon_variant	0.88	linezolid	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476629	n.2972C>A	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1476629	n.2972C>A	non_coding_transcript_exon_variant	0.83	linezolid
rrl	1476630	n.2973A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476630	n.2973A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rpsA	1834249	c.708T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834264	c.723G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834294	c.753G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834298	p.Gln253Glu	missense_variant	1.0	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	0.92	pyrazinamide
rpsA	1834307	c.766_768delGACinsCG	frameshift_variant&missense_variant	1.0	pyrazinamide	Uncertain significance
rpsA	1834312	c.771G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1834327	c.786G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834345	c.804C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834348	c.807T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834354	c.813G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834357	c.816T>C	synonymous_variant	0.86	pyrazinamide
rpsA	1834360	c.819G>C	synonymous_variant	0.86	pyrazinamide
rpsA	1834361	c.820T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834366	c.825A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834375	c.834G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834378	c.837T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834387	c.846C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834395	p.Arg285Gln	missense_variant	0.92	pyrazinamide
rpsA	1834397	p.His286Ala	missense_variant	0.91	pyrazinamide
rpsA	1834411	c.870T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834417	c.876G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834423	c.882G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834427	c.886_888delATCinsGT	frameshift_variant&missense_variant	1.0	pyrazinamide	Uncertain significance
rpsA	1834435	c.894G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834451	c.910T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834456	c.915T>C	synonymous_variant	0.8	pyrazinamide
rpsA	1834459	c.918G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834465	c.924T>C	synonymous_variant	1.0	pyrazinamide

Drug	Resistance	Supporting mutations	WHO confidence	Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin	rrs	n.888G>A	Uncertain significance	Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid

TB-Profiler result