Run ID: 0a1b7ec4-4703-436e-a37f-96c4d6891fae
Sample name:
Date: 29-11-2023 10:32:31
Number of reads: 219483
Percentage reads mapped: 53.82
Median coverage: 8
Strain: La3
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| La3 | M.orygis | None | 0.95 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | rrs | n.888G>A | Uncertain significance | |
| amikacin | rrs | n.1402C>A | Uncertain significance | |
| n.1484G>T | Assoc w R - interim | |||
| kanamycin | rrs | n.1402C>A | Uncertain significance | |
| n.1484G>T | Assoc w R | |||
| capreomycin | rrs | n.1402C>A | Uncertain significance | |
| n.1484G>T | Assoc w R | |||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rrs | 1472733 | n.888G>A | non_coding_transcript_exon_variant | 0.65 | streptomycin | Uncertain significance | |
| rrs | 1473247 | n.1402C>A | non_coding_transcript_exon_variant | 0.52 | kanamycin | Uncertain significance | |
| capreomycin | Uncertain significance | ||||||
| aminoglycosides | Uncertain significance | ||||||
| amikacin | Uncertain significance | ||||||
| rrs | 1473329 | n.1484G>T | non_coding_transcript_exon_variant | 0.5 | kanamycin | Assoc w R | |
| capreomycin | Assoc w R | ||||||
| aminoglycosides | Uncertain significance | ||||||
| amikacin | Assoc w R - interim |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 6098 | p.Val287Leu | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6109 | c.870G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6125 | p.Gly296Trp | missense_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6147 | p.Thr303Ser | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6180 | p.Gly314Val | missense_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6446 | p.Ala403Ser | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6717 | p.Ile493Thr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6916 | c.-386G>T | upstream_gene_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7311 | p.Thr4Ala | missense_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7437 | p.Asp46Tyr | missense_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7988 | c.687G>A | synonymous_variant | 0.2 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8118 | p.Glu273* | stop_gained | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8930 | c.1629C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| fgd1 | 490661 | c.-122_-121insGCGAGC | upstream_gene_variant | 0.92 | delamanid | |
| fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | delamanid | |
| fgd1 | 491749 | p.Leu323Phe | missense_variant | 1.0 | delamanid | Uncertain significance |
| mshA | 576060 | p.Val238Ala | missense_variant | 0.2 | ethionamide | |
| isoniazid | ||||||
| rpoB | 763285 | p.Leu1160Gln | missense_variant | 0.14 | rifampicin | |
| rpoC | 763827 | p.Ala153Gly | missense_variant | 0.15 | rifampicin | |
| rpoC | 763904 | p.Ala179Ser | missense_variant | 0.15 | rifampicin | |
| rpoC | 764318 | p.Val317Phe | missense_variant | 0.2 | rifampicin | |
| mmpL5 | 776025 | p.Ser819* | stop_gained | 0.2 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776095 | p.Arg796Ser | missense_variant | 0.18 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776549 | c.1932C>A | synonymous_variant | 0.18 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776976 | p.Ser502Ile | missense_variant | 0.18 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778086 | c.394dupG | frameshift_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpR5 | 779382 | p.Gln131His | missense_variant | 0.17 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 779516 | c.-611C>A | upstream_gene_variant | 0.15 | clofazimine | |
| bedaquiline | ||||||
| rplC | 801026 | c.221_223delGCG | disruptive_inframe_deletion | 0.2 | linezolid | |
| fbiC | 1302899 | c.-32A>G | upstream_gene_variant | 1.0 | delamanid | Uncertain significance |
| fbiC | 1303710 | p.Leu260Phe | missense_variant | 0.14 | delamanid | |
| fbiC | 1304498 | p.Pro523His | missense_variant | 0.17 | delamanid | |
| fbiC | 1304589 | c.1661delT | frameshift_variant | 0.17 | delamanid | |
| embR | 1416955 | p.Phe131Leu | missense_variant | 0.12 | ethambutol | |
| rrs | 1471866 | n.21C>A | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472337 | n.492C>T | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472379 | n.534T>C | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472400 | n.555C>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472422 | n.577T>C | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472427 | n.582T>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472449 | n.604C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472460 | n.615T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472467 | n.622G>T | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472473 | n.628G>T | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472474 | n.629C>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472476 | n.631A>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472494 | n.649A>G | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472507 | n.662C>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472517 | n.672T>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472518 | n.673G>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.21 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472537 | n.692C>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472544 | n.699C>A | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472545 | n.700A>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472566 | n.721G>A | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472579 | n.734G>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472580 | n.735C>T | non_coding_transcript_exon_variant | 0.26 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472581 | n.736A>T | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472598 | n.753A>C | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472599 | n.754G>T | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472658 | n.813G>A | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472680 | n.835C>T | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472681 | n.837_838delTT | non_coding_transcript_exon_variant | 0.45 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472687 | n.842_843insC | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472690 | n.845C>A | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472697 | n.852T>C | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472716 | n.871C>T | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.51 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472803 | n.958T>A | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472824 | n.979T>A | non_coding_transcript_exon_variant | 0.26 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472827 | n.982G>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472828 | n.983T>C | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472861 | n.1016G>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472875 | n.1030T>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472952 | n.1107T>C | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472955 | n.1110C>T | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472980 | n.1135G>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472989 | n.1144G>A | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472992 | n.1147A>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473005 | n.1160C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.71 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.71 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473080 | n.1235C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473081 | n.1236C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473093 | n.1248C>T | non_coding_transcript_exon_variant | 0.77 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473102 | n.1257C>T | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473115 | n.1270G>T | non_coding_transcript_exon_variant | 0.48 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473130 | n.1285G>A | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473252 | n.1407T>C | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 0.48 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473270 | n.1425G>A | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473305 | n.1460G>T | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473328 | n.1483C>A | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473338 | n.1493A>G | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473352 | n.1507C>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1474164 | n.507C>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474171 | n.514C>T | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474197 | n.540C>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474199 | n.542G>A | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474202 | n.545T>C | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 0.29 | linezolid | Uncertain significance |
| rrl | 1474275 | n.618T>G | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1474280 | n.623C>T | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1474281 | n.624A>G | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1474284 | n.631_633delCCT | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474293 | n.637_651delCCTCTCCGGAGGAGG | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474316 | n.659T>C | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| rrl | 1474317 | n.660G>A | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| rrl | 1474348 | n.691C>T | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474351 | n.694G>T | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474353 | n.696A>T | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474354 | n.697C>T | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| rrl | 1474383 | n.726G>T | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| rrl | 1474488 | n.831G>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474508 | n.851C>T | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474527 | n.870T>C | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474528 | n.871T>A | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474529 | n.872A>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474530 | n.873G>A | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.45 | linezolid | |
| rrl | 1474539 | n.882C>T | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474540 | n.883T>G | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474541 | n.884G>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474542 | n.885A>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474584 | n.927C>T | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| rrl | 1474672 | n.1015C>T | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1474674 | n.1017A>C | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1474675 | n.1018C>A | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474676 | n.1019T>C | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1474677 | n.1020A>G | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474694 | n.1037C>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474709 | n.1053_1056delTGGT | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474717 | n.1060_1061insGTGAG | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474723 | n.1066G>A | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474734 | n.1077G>A | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1474736 | n.1079C>T | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474751 | n.1094G>A | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1474777 | n.1120T>C | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474779 | n.1122G>A | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| rrl | 1474780 | n.1123C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1474782 | n.1125G>A | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| rrl | 1474783 | n.1126G>A | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| rrl | 1474801 | n.1144G>A | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1474802 | n.1145T>C | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.39 | linezolid | |
| rrl | 1474827 | n.1170C>T | non_coding_transcript_exon_variant | 0.28 | linezolid | |
| rrl | 1474830 | n.1173A>T | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1474831 | n.1174A>T | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1474832 | n.1175A>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474883 | n.1226T>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475699 | n.2042C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1475751 | n.2094C>A | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1475758 | n.2101A>G | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1475761 | n.2104C>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1475762 | n.2105G>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1475764 | n.2107A>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1475765 | n.2108A>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1475766 | n.2109G>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1475769 | n.2112T>C | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1475777 | n.2120A>T | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1475943 | n.2286G>A | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1476130 | n.2473G>A | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476135 | n.2478T>C | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1476141 | n.2484A>G | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1476153 | n.2496T>C | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1476165 | n.2508T>G | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.33 | linezolid | Uncertain significance |
| rrl | 1476195 | n.2538C>A | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1476196 | n.2539C>A | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1476204 | n.2547C>A | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1476210 | n.2553G>T | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1476211 | n.2554G>T | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1476212 | n.2555T>C | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1476214 | n.2557G>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1476215 | n.2558C>A | non_coding_transcript_exon_variant | 0.28 | linezolid | |
| rrl | 1476225 | n.2568T>G | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1476227 | n.2570C>T | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| rrl | 1476229 | n.2572C>T | non_coding_transcript_exon_variant | 0.32 | linezolid | |
| rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1476250 | n.2593C>G | non_coding_transcript_exon_variant | 0.32 | linezolid | |
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.37 | linezolid | |
| rrl | 1476252 | n.2595T>A | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476253 | n.2596A>G | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1476256 | n.2599A>G | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.48 | linezolid | Uncertain significance |
| rrl | 1476280 | n.2623A>C | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476293 | n.2636C>T | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1476294 | n.2637A>G | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| rrl | 1476295 | n.2638C>G | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| rrl | 1476296 | n.2639C>T | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.48 | linezolid | |
| rrl | 1476299 | n.2642C>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476300 | n.2643G>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| rrl | 1476302 | n.2645G>A | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| rrl | 1476308 | n.2651G>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| rrl | 1476312 | n.2655T>C | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| rrl | 1476313 | n.2656G>A | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| rrl | 1476332 | n.2675G>C | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1476337 | n.2680C>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1476338 | n.2681C>T | non_coding_transcript_exon_variant | 0.48 | linezolid | Uncertain significance |
| rrl | 1476353 | n.2696G>T | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| rrl | 1476358 | n.2701T>C | non_coding_transcript_exon_variant | 0.44 | linezolid | |
| rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1476382 | n.2725A>G | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| rrl | 1476383 | n.2726T>A | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| rrl | 1476425 | n.2768G>T | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.15 | linezolid | Uncertain significance |
| rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| rrl | 1476491 | n.2834T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1476514 | n.2857C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476515 | n.2858C>T | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1476529 | n.2872A>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1476530 | n.2873C>T | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| rrl | 1476531 | n.2874T>G | non_coding_transcript_exon_variant | 0.21 | linezolid | |
| rrl | 1476573 | n.2916A>G | non_coding_transcript_exon_variant | 0.3 | linezolid | Uncertain significance |
| rrl | 1476594 | n.2937C>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| inhA | 1673680 | c.-522C>G | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1674942 | c.741T>C | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833370 | c.-172G>A | upstream_gene_variant | 0.12 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834294 | c.753G>C | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1834298 | p.Gln253Glu | missense_variant | 0.2 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1834307 | p.Asp256Gln | missense_variant | 0.2 | pyrazinamide | |
| rpsA | 1834318 | c.777C>G | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1834327 | c.786G>C | synonymous_variant | 0.15 | pyrazinamide | |
| rpsA | 1834330 | c.789C>G | synonymous_variant | 0.15 | pyrazinamide | |
| rpsA | 1834345 | p.Asp268Glu | missense_variant | 0.13 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.13 | pyrazinamide | |
| rpsA | 1834354 | c.813G>C | synonymous_variant | 0.13 | pyrazinamide | |
| rpsA | 1834357 | c.816T>C | synonymous_variant | 0.13 | pyrazinamide | |
| rpsA | 1834360 | c.819G>C | synonymous_variant | 0.13 | pyrazinamide | |
| rpsA | 1834361 | c.820_822delTTGinsCTA | synonymous_variant | 0.13 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 0.13 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 0.12 | pyrazinamide | |
| rpsA | 1834414 | c.873C>T | synonymous_variant | 0.17 | pyrazinamide | |
| tlyA | 1918074 | c.135C>T | synonymous_variant | 0.12 | capreomycin | |
| katG | 2154030 | c.2082G>T | synonymous_variant | 0.2 | isoniazid | |
| katG | 2154707 | p.Val469Leu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155503 | c.609C>T | synonymous_variant | 1.0 | isoniazid | |
| PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| PPE35 | 2167983 | p.Gly877Asp | missense_variant | 0.12 | pyrazinamide | Uncertain significance |
| PPE35 | 2168102 | c.2511C>T | synonymous_variant | 0.11 | pyrazinamide | |
| PPE35 | 2169279 | c.1312_1333delAACAATGGTGTCTTTTACCGTG | frameshift_variant | 1.0 | pyrazinamide | |
| PPE35 | 2169493 | p.Val374Ile | missense_variant | 0.14 | pyrazinamide | |
| PPE35 | 2169542 | c.1071C>T | synonymous_variant | 0.15 | pyrazinamide | |
| PPE35 | 2169562 | p.Leu351Val | missense_variant | 0.12 | pyrazinamide | |
| PPE35 | 2169598 | p.Phe339Ile | missense_variant | 0.1 | pyrazinamide | |
| Rv1979c | 2222162 | p.Val335Phe | missense_variant | 0.11 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| Rv1979c | 2222715 | c.450C>A | synonymous_variant | 0.13 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| pncA | 2289032 | c.210G>T | synonymous_variant | 0.12 | pyrazinamide | |
| kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518772 | p.Asn220Asp | missense_variant | 0.2 | isoniazid | |
| eis | 2714977 | p.His119Arg | missense_variant | 0.13 | kanamycin | |
| amikacin | ||||||
| ahpC | 2726378 | c.186T>A | synonymous_variant | 1.0 | isoniazid | |
| Rv2752c | 3064874 | p.Gly440Ser | missense_variant | 0.15 | rifampicin | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3066370 | c.-179G>A | upstream_gene_variant | 0.17 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3067009 | c.-818A>G | upstream_gene_variant | 1.0 | rifampicin | |
| isoniazid | ||||||
| thyX | 3067698 | p.Thr83Asn | missense_variant | 0.13 | para-aminosalicylic_acid | |
| thyX | 3067812 | p.Gln45Arg | missense_variant | 1.0 | para-aminosalicylic_acid | |
| ald | 3086728 | c.-92C>T | upstream_gene_variant | 1.0 | cycloserine | |
| ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
| ald | 3086796 | c.-24C>T | upstream_gene_variant | 0.12 | cycloserine | |
| ald | 3086802 | c.-18G>T | upstream_gene_variant | 0.12 | cycloserine | |
| ald | 3087084 | c.266delA | frameshift_variant | 1.0 | cycloserine | |
| ald | 3087608 | c.789A>T | synonymous_variant | 0.12 | cycloserine | |
| Rv3083 | 3449385 | c.882C>T | synonymous_variant | 0.17 | ethionamide | |
| fprA | 3474348 | c.342C>A | synonymous_variant | 0.12 | capreomycin | |
| amikacin | ||||||
| fprA | 3474364 | p.Pro120Thr | missense_variant | 0.12 | capreomycin | |
| amikacin | ||||||
| fprA | 3474722 | p.Ala239Asp | missense_variant | 0.14 | capreomycin | |
| amikacin | ||||||
| fprA | 3474822 | p.Leu272Phe | missense_variant | 0.2 | capreomycin | |
| amikacin | ||||||
| Rv3236c | 3612230 | p.Ala296Val | missense_variant | 0.15 | pyrazinamide | |
| Rv3236c | 3613060 | c.57G>T | synonymous_variant | 0.18 | pyrazinamide | |
| fbiB | 3641580 | p.Pro16Thr | missense_variant | 0.2 | delamanid | |
| fbiB | 3641584 | p.Val17Ala | missense_variant | 1.0 | delamanid | Uncertain significance |
| fbiB | 3641667 | p.Val45Ile | missense_variant | 0.17 | delamanid | |
| alr | 3840614 | p.Met269Ile | missense_variant | 0.12 | cycloserine | |
| alr | 3840855 | p.Arg189Gln | missense_variant | 0.11 | cycloserine | |
| rpoA | 3877557 | c.951C>T | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3878170 | p.Pro113Leu | missense_variant | 0.17 | rifampicin | |
| clpC1 | 4038533 | c.2172C>A | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4040285 | p.Gln140His | missense_variant | 0.2 | pyrazinamide | |
| embC | 4241473 | c.1611G>A | synonymous_variant | 0.18 | ethambutol | |
| embC | 4241502 | p.Ser547Leu | missense_variant | 0.17 | ethambutol | Uncertain significance |
| embC | 4241528 | p.Arg556Cys | missense_variant | 0.2 | ethambutol | |
| embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4243516 | p.Ala95Asp | missense_variant | 0.2 | ethambutol | |
| embA | 4243518 | p.Gly96Ser | missense_variant | 0.2 | ethambutol | |
| embB | 4248103 | c.1590G>T | synonymous_variant | 0.2 | ethambutol | |
| embB | 4248493 | p.Met660Ile | missense_variant | 0.11 | ethambutol | |
| aftB | 4268540 | p.Met99Ile | missense_variant | 0.18 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| ethA | 4327788 | c.-315G>T | upstream_gene_variant | 0.2 | ethionamide | |
| whiB6 | 4338269 | p.Gly85Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| whiB6 | 4338387 | c.135C>A | synonymous_variant | 0.18 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| gid | 4407821 | c.382T>C | synonymous_variant | 0.12 | streptomycin |
