Run ID: 28a56603-503d-41b3-8561-84ff4ac5ca87
Sample name:
Date: 02-04-2024 07:07:49
Number of reads: 15128
Percentage reads mapped: 3.93
Median coverage: 0
Strain: lineage2.1
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage2.1 | East-Asian (non-Beijing) | None | 1.0 |
| lineage2.2.2 | East-Asian (Beijing) | RD105;RD207 | 0.8 |
| lineage6.3.1 | West-Africa 2 | RD702 | 1.0 |
| lineage4.3.1 | Euro-American (LAM) | None | 1.0 |
| lineage4.8.1 | Euro-American (mainly T) | RD219 | 0.36 |
| lineage3.1.2.2 | East-African-Indian | RD750 | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | ||||
| amikacin | ||||
| kanamycin | ||||
| capreomycin | ||||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7565 | c.264C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7569 | p.Ala90Ser | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760244 | c.438G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760316 | c.510C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760325 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760334 | c.528G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760357 | p.Thr184Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 760415 | c.609C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760433 | c.627C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760457 | c.651C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760463 | c.657C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760478 | c.672C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760481 | c.675G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760502 | c.696C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762245 | c.2439G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762287 | c.2481C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762308 | c.2502G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762314 | c.2508C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762341 | c.2535G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762350 | c.2544C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762374 | c.-996G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762404 | c.-966T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762416 | c.-954A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762443 | c.-927G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762449 | c.-921C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762452 | c.-918G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762470 | c.-900G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764485 | c.1116G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764491 | c.1122G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764500 | c.1131C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764536 | c.1167G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764605 | c.1236G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764623 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764701 | c.1332C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764713 | c.1344G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764851 | c.1482C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764875 | c.1506C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781901 | c.342C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472019 | n.174G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472023 | n.178G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472031 | n.186G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472033 | n.188A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472035 | n.190G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472040 | n.195T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472042 | n.197T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472380 | n.535G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472846 | n.1001C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472861 | n.1016G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473291 | n.1446_1447insT | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474417 | n.761_767delCACGCGC | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474427 | n.770A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474432 | n.775C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474434 | n.777_778insTG | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474437 | n.781_782delAA | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474446 | n.789C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474629 | n.972G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474639 | n.982G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474640 | n.983C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474676 | n.1019T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474677 | n.1020A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474710 | n.1053T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474711 | n.1054G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474712 | n.1055G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474713 | n.1056T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475429 | n.1772G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475479 | n.1822C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475531 | n.1874C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475603 | n.1946G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475612 | n.1955G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475615 | n.1958C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475616 | n.1959A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475618 | n.1961C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475629 | n.1972G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475637 | n.1980T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475638 | n.1981C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475643 | n.1986C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475647 | n.1990G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475753 | n.2096C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475762 | n.2105G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475764 | n.2107A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475765 | n.2108A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475775 | n.2118G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1475991 | n.2334T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476033 | n.2376T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476105 | n.2448G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476251 | n.2594T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476540 | n.2883C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476665 | n.3008T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476679 | n.3022T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833976 | c.435C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833991 | c.450C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834213 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834234 | c.693G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834279 | c.738C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834345 | c.804C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834361 | c.820T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834498 | c.957C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834513 | c.972C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834520 | p.Ala327Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834543 | c.1002C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834554 | c.1014_1015delTG | frameshift_variant | 1.0 | pyrazinamide | |
| rpsA | 1834558 | c.1017_1018insAG | frameshift_variant | 1.0 | pyrazinamide | |
| rpoA | 3878082 | c.426T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878127 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878197 | p.Glu104Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878199 | c.309T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878244 | c.264G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878301 | c.207C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878304 | c.204G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878310 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878352 | c.156C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878358 | c.150C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878361 | c.147G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878367 | c.141C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878373 | c.135G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878400 | c.108T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878403 | c.105C>T | synonymous_variant | 1.0 | rifampicin | |
| clpC1 | 4038842 | c.1863G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038890 | c.1815G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038905 | c.1800A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039025 | c.1680C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039067 | c.1638G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039079 | c.1626C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039091 | c.1614G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040015 | c.690G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040057 | c.648C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040126 | c.579C>T | synonymous_variant | 1.0 | pyrazinamide |
