TB-Profiler result

Run: ERR9786164
Summary

Run ID: ERR9786164

Sample name:

Date: 02-04-2023 12:10:38

Number of reads: 683881

Percentage reads mapped: 55.85

Strain: lineage4.1.1.3

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.42 rifampicin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.5 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.27 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 760965 p.Met387Leu missense_variant 0.16
rpoB 760970 c.1164G>C synonymous_variant 0.19
rpoB 760973 c.1167G>C synonymous_variant 0.17
rpoB 760982 c.1176G>C synonymous_variant 0.2
rpoB 760985 c.1179G>C synonymous_variant 0.2
rpoB 760991 c.1185G>C synonymous_variant 0.3
rpoB 760997 c.1191G>C synonymous_variant 0.34
rpoB 761006 c.1200C>G synonymous_variant 0.39
rpoB 761013 p.Val403Ile missense_variant 0.42
rpoB 761027 c.1221A>G synonymous_variant 0.45
rpoB 761036 c.1230G>C synonymous_variant 0.47
rpoB 761037 c.1231T>C synonymous_variant 0.48
rpoB 761046 p.Ile414Val missense_variant 0.48
rpoB 761051 c.1245G>C synonymous_variant 0.52
rpoB 761054 c.1248G>C synonymous_variant 0.52
rpoB 761057 c.1251G>C synonymous_variant 0.52
rpoB 761087 c.1281C>G synonymous_variant 0.52
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.52
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.48
rpoB 761102 c.1296A>G synonymous_variant 0.45
rpoB 761126 c.1320G>C synonymous_variant 0.42
rpoB 761132 c.1326G>T synonymous_variant 0.42
rpoB 761133 c.1327T>C synonymous_variant 0.44
rpoB 761150 c.1344A>C synonymous_variant 0.41
rpoB 761162 c.1356G>C synonymous_variant 0.34
rpoB 761165 c.1359G>C synonymous_variant 0.34
rpoB 761171 c.1365C>T synonymous_variant 0.34
rpoB 761175 c.1371_1372delGT frameshift_variant 0.32
rpoB 761180 c.1374_1375insGC frameshift_variant 0.33
rpoB 761189 c.1383T>C synonymous_variant 0.35
rpoB 761195 c.1389G>C synonymous_variant 0.35
rpoB 761196 p.Leu464Val missense_variant 0.35
rpoB 761207 c.1401C>T synonymous_variant 0.35
rpoB 761213 c.1407G>C synonymous_variant 0.33
rpoB 761234 c.1428G>C synonymous_variant 0.26
rpoB 761249 c.1443A>G synonymous_variant 0.16
rpoB 762879 p.Met1025Leu missense_variant 0.12
rpoC 762896 c.-474G>C upstream_gene_variant 0.19
rpoC 762929 c.-441G>C upstream_gene_variant 0.23
rpoC 762932 c.-438G>C upstream_gene_variant 0.23
rpoC 762947 c.-423C>G upstream_gene_variant 0.26
rpoC 762962 c.-408C>T upstream_gene_variant 0.3
rpoC 762980 c.-390T>C upstream_gene_variant 0.32
rpoC 762989 c.-381G>C upstream_gene_variant 0.31
rpoC 762995 c.-375G>C upstream_gene_variant 0.3
rpoB 763005 p.Cys1067Val missense_variant 0.3
rpoC 763013 c.-357C>G upstream_gene_variant 0.29
rpoB 763014 p.Met1070Leu missense_variant 0.3
rpoB 763017 p.Gln1071Glu missense_variant 0.29
rpoC 763031 c.-339T>C upstream_gene_variant 0.25
rpoC 763034 c.-336C>G upstream_gene_variant 0.24
rpoB 763038 p.Thr1078Ala missense_variant 0.25
rpoC 763052 c.-318G>C upstream_gene_variant 0.28
rpoC 763053 c.-317T>C upstream_gene_variant 0.28
rpoC 763058 c.-312C>G upstream_gene_variant 0.29
rpoC 763070 c.-300T>C upstream_gene_variant 0.31
rpoB 763075 p.Thr1090Ile missense_variant 0.31
rpoC 763094 c.-276G>C upstream_gene_variant 0.29
rpoC 763115 c.-255T>C upstream_gene_variant 0.25
rpoB 763126 p.Pro1107Gln missense_variant 0.24
rpoC 763148 c.-222G>C upstream_gene_variant 0.12
rpoC 763483 c.114G>C synonymous_variant 0.12
rpoC 763486 c.117T>C synonymous_variant 0.12
rpoC 763492 c.123G>C synonymous_variant 0.12
rpoC 763504 c.135C>T synonymous_variant 0.16
rpoC 763511 p.Cys48Gly missense_variant 0.15
rpoC 763517 p.Lys50Gln missense_variant 0.16
rpoC 763528 c.159G>C synonymous_variant 0.17
rpoC 763531 c.162G>T synonymous_variant 0.17
rpoC 763532 p.Thr55Ser missense_variant 0.17
rpoC 763540 c.171C>T synonymous_variant 0.18
rpoC 763546 c.177A>G synonymous_variant 0.17
rpoC 763550 p.Tyr61Ala missense_variant 0.17
rpoC 763570 c.201G>C synonymous_variant 0.19
rpoC 763573 c.204G>C synonymous_variant 0.19
rpoC 763589 p.Ile74Val missense_variant 0.22
rpoC 763614 c.246_251delGACCCG disruptive_inframe_deletion 0.17
rpoC 763622 p.Ala85Thr missense_variant 0.17
rpoC 763642 c.273G>C synonymous_variant 0.21
rpoC 763660 c.291T>C synonymous_variant 0.21
rpoC 763666 c.297G>C synonymous_variant 0.21
rpoC 763696 c.327T>C synonymous_variant 0.17
rpoC 763708 c.339G>C synonymous_variant 0.12
rpoC 763711 c.342G>C synonymous_variant 0.13
rpoC 763714 c.345G>A synonymous_variant 0.13
rpoC 763717 c.348T>C synonymous_variant 0.14
rpoC 763723 c.354G>C synonymous_variant 0.14
rpoC 763727 p.Leu120Met missense_variant 0.14
rpoC 763732 c.363C>G synonymous_variant 0.14
rpoC 763765 c.396T>C synonymous_variant 0.12
rpoC 763772 p.Val135Met missense_variant 0.13
rpoC 763775 p.Ile136Val missense_variant 0.13
rpoC 763779 p.Thr137Ile missense_variant 0.12
rpoC 764353 c.984G>C synonymous_variant 0.19
rpoC 764365 c.996C>T synonymous_variant 0.21
rpoC 764371 c.1002G>C synonymous_variant 0.21
rpoC 764380 c.1011G>C synonymous_variant 0.21
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.21
rpoC 764387 c.1018T>C synonymous_variant 0.24
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.33
rpoC 764428 c.1059G>C synonymous_variant 0.35
rpoC 764431 c.1062G>C synonymous_variant 0.35
rpoC 764432 p.Lys355Arg missense_variant 0.35
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.36
rpoC 764446 c.1077T>C synonymous_variant 0.37
rpoC 764449 c.1080G>C synonymous_variant 0.37
rpoC 764455 c.1086G>C synonymous_variant 0.38
rpoC 764458 c.1089G>C synonymous_variant 0.39
rpoC 764461 c.1092A>G synonymous_variant 0.4
rpoC 764470 c.1101C>G synonymous_variant 0.46
rpoC 764497 c.1128A>G synonymous_variant 0.5
rpoC 764498 p.Ser377Ala missense_variant 0.51
rpoC 764503 c.1134G>C synonymous_variant 0.53
rpoC 764509 c.1140G>C synonymous_variant 0.53
rpoC 764521 c.1152T>C synonymous_variant 0.53
rpoC 764533 c.1164C>T synonymous_variant 0.52
rpoC 764536 c.1167G>T synonymous_variant 0.54
rpoC 764548 c.1179G>T synonymous_variant 0.52
rpoC 764549 p.Pro394Thr missense_variant 0.52
rpoC 764561 p.Pro398Ala missense_variant 0.55
rpoC 764566 c.1197C>G synonymous_variant 0.56
rpoC 764575 c.1206T>G synonymous_variant 0.52
rpoC 764581 c.1212T>C synonymous_variant 0.47
rpoC 764582 p.Leu405Met missense_variant 0.47
rpoC 764611 c.1242G>C synonymous_variant 0.45
rpoC 764632 c.1263T>C synonymous_variant 0.4
rpoC 764635 c.1266C>G synonymous_variant 0.39
rpoC 764650 c.1281G>T synonymous_variant 0.25
rpoC 764660 p.Val431Ile missense_variant 0.25
rpoC 764677 c.1308C>G synonymous_variant 0.25
rpoC 764683 c.1314G>C synonymous_variant 0.23
rpoC 764692 c.1323C>T synonymous_variant 0.23
rpoC 764705 p.Leu446Ala missense_variant 0.16
rpoC 764716 c.1347G>C synonymous_variant 0.13
rpoC 764824 c.1455T>C synonymous_variant 0.18
rpoC 764837 p.Val490Ile missense_variant 0.14
rpoC 764843 p.Ala492Arg missense_variant 0.14
rpoC 764850 p.His494Arg missense_variant 0.14
rpoC 764854 c.1485G>C synonymous_variant 0.14
rpoC 764858 c.1489T>C synonymous_variant 0.14
rpoC 764863 c.1494G>C synonymous_variant 0.14
rpoC 764872 c.1503A>T synonymous_variant 0.15
rpoC 764878 c.1509C>G synonymous_variant 0.14
rpoC 764887 c.1518G>C synonymous_variant 0.15
rpoC 764888 c.1519T>C synonymous_variant 0.17
rpoC 764893 c.1524T>C synonymous_variant 0.18
rpoC 764911 c.1542A>G synonymous_variant 0.13
rpoC 764912 p.Met515Leu missense_variant 0.13
rpoC 764917 c.1548G>C synonymous_variant 0.12
rpoC 764923 c.1554A>G synonymous_variant 0.13
rpoC 764935 c.1566T>C synonymous_variant 0.15
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 0.14
rpoC 764953 c.1584G>C synonymous_variant 0.15
rpoC 764956 c.1587T>C synonymous_variant 0.15
rpoC 764958 p.Glu530Ala missense_variant 0.15
rpoC 764968 c.1599T>C synonymous_variant 0.14
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.25
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.29
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.3
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.3
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.24
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.26
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.28
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.35
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.33
rrs 1472256 n.411T>C non_coding_transcript_exon_variant 0.33
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 0.25
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.24
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.24
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.23
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.23
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.26
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.25
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.26
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.26
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.26
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.26
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.24
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.29
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.24
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.23
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.16
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.18
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.18
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.2
rrs 1472507 n.662C>T non_coding_transcript_exon_variant 0.25
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.3
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.3
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.3
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.34
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.39
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.4
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.38
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 0.42
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.35
rrs 1472660 n.815T>A non_coding_transcript_exon_variant 0.34
rrs 1472666 n.821G>T non_coding_transcript_exon_variant 0.35
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.32
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.32
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.3
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.3
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.3
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.3
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.3
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.31
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.3
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.31
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.18
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.19
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.15
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.23
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.23
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.23
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.2
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.29
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.29
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.31
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.34
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.44
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.56
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.54
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.48
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.51
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.51
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.51
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.51
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.52
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.53
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.55
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.55
rrs 1473134 n.1289T>C non_coding_transcript_exon_variant 0.54
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.57
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.57
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.59
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.6
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.53
rrs 1473269 n.1424C>T non_coding_transcript_exon_variant 0.42
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.41
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.4
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.33
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.36
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.32
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.23
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.23
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.23
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.14
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.12
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.11
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.11
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.11
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.12
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.13
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.13
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.14
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.15
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.15
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.14
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.14
rrl 1474376 n.719T>A non_coding_transcript_exon_variant 0.19
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.19
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.11
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.12
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.19
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.2
rrl 1474488 n.831G>C non_coding_transcript_exon_variant 0.21
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.21
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.26
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.29
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.29
rrl 1474516 n.859C>G non_coding_transcript_exon_variant 0.33
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.35
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.37
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.29
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.29
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.23
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.23
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.22
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.19
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.21
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.32
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.23
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.24
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.24
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.25
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.28
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.28
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.28
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.28
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.28
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.27
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.26
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.27
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.29
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.26
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.26
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.28
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.29
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.3
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.32
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.32
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.28
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.28
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.28
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.35
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.31
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.28
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.24
rrl 1474935 n.1278A>G non_coding_transcript_exon_variant 0.17
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 0.15
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.14
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.26
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.39
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.35
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.37
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.37
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.36
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.47
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.44
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.36
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.35
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.33
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.31
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.33
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.32
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.35
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.24
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.21
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.21
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.21
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.21
rrl 1476046 n.2389G>C non_coding_transcript_exon_variant 0.21
rrl 1476047 n.2390G>C non_coding_transcript_exon_variant 0.21
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.21
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.21
rrl 1476079 n.2422G>A non_coding_transcript_exon_variant 0.21
rrl 1476080 n.2423T>C non_coding_transcript_exon_variant 0.21
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.21
rrl 1476082 n.2425T>C non_coding_transcript_exon_variant 0.21
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.21
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.21
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.21
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.21
rrl 1476104 n.2448delG non_coding_transcript_exon_variant 0.21
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.2
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.2
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.23
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.33
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.33
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.4
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.4
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.39
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.37
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.39
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.39
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.4
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.44
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.41
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.41
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.41
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.41
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.4
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.41
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.42
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.42
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.5
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.47
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.47
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.38
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.25
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.2
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.18
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.14
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.14
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.14
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.14
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.14
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.13
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.14
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.14
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.15
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.13
rpsA 1833709 c.168C>G synonymous_variant 0.13
rpsA 1833721 c.180A>G synonymous_variant 0.18
rpsA 1833727 c.186G>C synonymous_variant 0.2
rpsA 1833734 p.Ala65Ser missense_variant 0.19
rpsA 1833742 c.201A>G synonymous_variant 0.24
rpsA 1833745 c.204G>C synonymous_variant 0.24
rpsA 1833769 c.228C>G synonymous_variant 0.22
rpsA 1833781 c.240T>C synonymous_variant 0.24
rpsA 1833782 p.Ser81Lys missense_variant 0.24
rpsA 1833790 c.249T>C synonymous_variant 0.26
rpsA 1833808 c.267G>C synonymous_variant 0.26
rpsA 1833811 c.270G>C synonymous_variant 0.26
rpsA 1833815 p.Thr92Gln missense_variant 0.26
rpsA 1833829 c.288A>G synonymous_variant 0.29
rpsA 1833832 c.291G>A synonymous_variant 0.29
rpsA 1833838 c.297G>C synonymous_variant 0.32
rpsA 1833856 c.315A>G synonymous_variant 0.38
rpsA 1833874 c.333T>C synonymous_variant 0.35
rpsA 1833884 p.Thr115Asp missense_variant 0.33
rpsA 1833887 p.Ile116Val missense_variant 0.33
rpsA 1833893 p.Ala118Lys missense_variant 0.33
rpsA 1833896 p.Leu119Ile missense_variant 0.34
rpsA 1833907 p.Lys122Asn missense_variant 0.29
rpsA 1833912 p.Glu124Gly missense_variant 0.29
rpsA 1833915 p.Ala125Val missense_variant 0.29
rpsA 1833921 p.Lys127Thr missense_variant 0.29
rpsA 1833928 c.387G>C synonymous_variant 0.3
rpsA 1833955 c.414G>C synonymous_variant 0.2
rpsA 1833959 p.Leu140Val missense_variant 0.2
rpsA 1833970 c.429G>C synonymous_variant 0.17
rpsA 1833979 c.438T>G synonymous_variant 0.16
rpsA 1833985 c.444G>C synonymous_variant 0.12
rpsA 1834279 p.Asp246Glu missense_variant 0.13
rpsA 1834283 p.Pro248Ala missense_variant 0.13
rpsA 1834294 c.753G>C synonymous_variant 0.14
rpsA 1834298 p.Gln253Glu missense_variant 0.13
rpsA 1834303 c.762T>G synonymous_variant 0.14
rpsA 1834306 c.765T>C synonymous_variant 0.15
rpsA 1834307 p.Asp256Gln missense_variant 0.15
rpsA 1834325 p.Val262Ile missense_variant 0.17
rpsA 1834333 p.Asp264Glu missense_variant 0.17
rpsA 1834340 p.Met267Leu missense_variant 0.16
rpsA 1834348 c.807T>C synonymous_variant 0.19
rpsA 1834354 c.813G>C synonymous_variant 0.2
rpsA 1834357 c.816T>C synonymous_variant 0.2
rpsA 1834361 c.820T>C synonymous_variant 0.2
rpsA 1834366 c.825A>G synonymous_variant 0.2
rpsA 1834369 c.828C>G synonymous_variant 0.2
rpsA 1834378 c.837T>G synonymous_variant 0.23
rpsA 1834384 c.843A>G synonymous_variant 0.23
rpsA 1834395 p.Arg285Gln missense_variant 0.21
rpsA 1834397 p.His286Val missense_variant 0.21
rpsA 1834411 c.870T>C synonymous_variant 0.27
rpsA 1834423 c.882G>T synonymous_variant 0.3
rpsA 1834427 p.Ile296Val missense_variant 0.3
rpsA 1834431 p.Val297Ala missense_variant 0.28
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.27
rpsA 1834456 c.915T>C synonymous_variant 0.22
rpsA 1834465 c.924T>C synonymous_variant 0.21
rpsA 1834468 c.927A>G synonymous_variant 0.21
rpsA 1834482 p.Glu314Ala missense_variant 0.19
rpsA 1834486 p.Glu315Asp missense_variant 0.19
rpsA 1834489 c.948T>C synonymous_variant 0.19
rpsA 1834501 c.960G>C synonymous_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168058 p.Gln852Arg missense_variant 0.2
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339178 p.Ala21Thr missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474504 c.498G>A synonymous_variant 1.0
embC 4239763 c.-100C>T upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0