Run ID: ERR4815022
Sample name:
Date: 2024-04-16T02:30:37.524179
Number of reads: 316333
Percentage reads mapped: 22.79
Median coverage: 6.0
Strain: lineage3.1.2.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage3 | East-African-Indian | RD750 | 1.0 |
lineage3.1.2 | East-African-Indian | RD750 | 0.5 |
lineage3.1.2.1 | East-African-Indian | RD750 | 1.0 |
lineage3.1 | East-African-Indian | RD750 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.799C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472644 | n.799C>T | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
rpoC | 762932 | c.-438G>T | upstream_gene_variant | 0.6 | rifampicin | |
rpoC | 762938 | c.-432G>C | upstream_gene_variant | 0.58 | rifampicin | |
rpoC | 762944 | c.-426C>T | upstream_gene_variant | 0.78 | rifampicin | |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.86 | rifampicin | |
rpoB | 762995 | c.3189G>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoB | 763005 | p.Cys1067Val | missense_variant | 0.76 | rifampicin | |
rpoC | 763013 | c.-357C>A | upstream_gene_variant | 0.73 | rifampicin | |
rpoC | 763022 | c.-348C>T | upstream_gene_variant | 0.74 | rifampicin | |
rpoC | 763025 | c.-345C>T | upstream_gene_variant | 0.74 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 763053 | c.3247T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763615 | c.246G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 763619 | p.Arg84Lys | missense_variant | 0.67 | rifampicin | |
rpoC | 763622 | p.Ala85Ser | missense_variant | 0.67 | rifampicin | Uncertain significance |
rpoC | 763630 | c.261G>T | synonymous_variant | 0.73 | rifampicin | |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>A | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764551 | c.1182G>T | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764572 | c.1203G>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>T | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764582 | c.1213C>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764605 | c.1236G>T | synonymous_variant | 0.68 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764623 | c.1254C>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764635 | c.1266C>T | synonymous_variant | 0.55 | rifampicin | |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764653 | c.1284G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764656 | c.1287C>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764659 | c.1290C>T | synonymous_variant | 0.45 | rifampicin | |
rpoC | 764660 | c.1291_1293delGTGinsAC | frameshift_variant&missense_variant | 0.45 | rifampicin | |
rpoC | 764887 | c.1518G>T | synonymous_variant | 0.58 | rifampicin | |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.62 | rifampicin | |
rpoC | 764913 | p.Met515Lys | missense_variant | 0.62 | rifampicin | |
rpoC | 764920 | c.1551G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764926 | c.1557C>T | synonymous_variant | 0.67 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 764952 | p.Val528Ala | missense_variant | 0.57 | rifampicin | |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764971 | c.1602C>T | synonymous_variant | 0.46 | rifampicin | |
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471927 | n.82_85delTTCGinsAGCTTGCT | non_coding_transcript_exon_variant | 0.94 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.94 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.95 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471978 | n.133C>T | non_coding_transcript_exon_variant | 0.88 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471996 | n.151C>T | non_coding_transcript_exon_variant | 0.82 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472078 | n.233C>T | non_coding_transcript_exon_variant | 0.84 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472123 | n.278A>T | non_coding_transcript_exon_variant | 0.93 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472150 | n.305T>G | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472151 | n.306C>A | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472160 | n.315C>T | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472225 | n.380C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472259 | n.414C>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472435 | n.590T>C | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472438 | n.593T>C | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472439 | n.594C>T | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472447 | n.602C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472448 | n.603T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472450 | n.605A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472451 | n.606C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472461 | n.616G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472462 | n.617T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472471 | n.626G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472484 | n.639A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>T | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472494 | n.649A>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472558 | n.713G>A | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472569 | n.724G>A | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472607 | n.762G>A | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472612 | n.767G>T | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472660 | n.815T>C | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472670 | n.825G>A | non_coding_transcript_exon_variant | 0.92 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.94 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472828 | n.983T>C | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125_1128delCGTAinsT | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472974 | n.1129A>T | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472977 | n.1133dupT | non_coding_transcript_exon_variant | 0.73 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472977 | n.1132G>T | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472977 | n.1133dupT | non_coding_transcript_exon_variant | 0.73 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472977 | n.1132G>T | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473080 | n.1235C>T | non_coding_transcript_exon_variant | 0.91 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473132 | n.1287T>C | non_coding_transcript_exon_variant | 0.82 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473135 | n.1290C>T | non_coding_transcript_exon_variant | 0.89 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 0.94 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473282 | n.1437_1438delCTinsTCA | non_coding_transcript_exon_variant | 0.91 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473285 | n.1442_1443delCC | non_coding_transcript_exon_variant | 0.92 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473292 | n.1447G>T | non_coding_transcript_exon_variant | 0.92 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473293 | n.1448G>T | non_coding_transcript_exon_variant | 0.92 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrl | 1473697 | n.40C>G | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1473698 | n.41G>C | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1473699 | n.42A>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1473718 | n.61G>A | non_coding_transcript_exon_variant | 0.86 | capreomycin | |
linezolid | ||||||
rrl | 1473719 | n.62G>A | non_coding_transcript_exon_variant | 0.86 | capreomycin | |
linezolid | ||||||
rrl | 1473728 | n.71A>T | non_coding_transcript_exon_variant | 0.86 | capreomycin | |
linezolid | ||||||
rrl | 1473731 | n.74T>A | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473743 | n.86C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1473750 | n.93C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1473751 | n.94C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1473752 | n.95G>A | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474182 | n.525C>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | |
linezolid | ||||||
rrl | 1474183 | n.526T>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | |
linezolid | ||||||
rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474185 | n.529delA | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1474197 | n.540C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474200 | n.545delT | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474253 | n.596A>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474263 | n.606G>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474351 | n.694G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474517 | n.860C>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1474527 | n.870T>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474542 | n.885A>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474736 | n.1079C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474751 | n.1094G>A | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474784 | n.1127C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474798 | n.1141C>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474825 | n.1168G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474837 | n.1180A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474896 | n.1239A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474901 | n.1244A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474921 | n.1264C>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475514 | n.1857G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475522 | n.1865A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475525 | n.1868G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475531 | n.1874C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475539 | n.1882A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475542 | n.1885A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475550 | n.1893A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475672 | n.2015C>T | non_coding_transcript_exon_variant | 0.77 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475673 | n.2016T>C | non_coding_transcript_exon_variant | 0.77 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475688 | n.2031G>A | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1475696 | n.2039T>A | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475699 | n.2042delCinsTT | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1475703 | n.2046A>T | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475704 | n.2047C>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
linezolid | ||||||
rrl | 1475713 | n.2056C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475758 | n.2101A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2108A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475769 | n.2112T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475879 | n.2222T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.96 | capreomycin | |
linezolid | ||||||
rrl | 1475883 | n.2226A>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475900 | n.2243A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475902 | n.2245T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475906 | n.2249C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475997 | n.2340A>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476033 | n.2376T>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1476034 | n.2377C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476080 | n.2423T>G | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
linezolid | ||||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476250 | n.2593C>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476256 | n.2599A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476262 | n.2605G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476298 | n.2641C>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1476300 | n.2643G>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476307 | n.2650A>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1476309 | n.2652G>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476524 | n.2867_2868delCAinsT | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1476535 | n.2878G>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | |
linezolid | ||||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476573 | n.2916A>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476607 | n.2950C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476624 | n.2967T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476630 | n.2973A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
Rv2680 | 2996212 | c.108C>T | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
clpC1 | 4038743 | p.Thr654Ile | missense_variant | 0.55 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>T | synonymous_variant | 0.59 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4038764 | c.1941C>G | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4038767 | c.1938G>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4038793 | c.1912C>T | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4038795 | p.Ser637Thr | missense_variant | 0.71 | pyrazinamide | |
clpC1 | 4038803 | c.1902C>T | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4038811 | p.Gln632Lys | missense_variant | 0.71 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.7 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>C | synonymous_variant | 0.72 | pyrazinamide | |
clpC1 | 4038836 | c.1869G>C | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4038839 | c.1866G>T | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4038851 | c.1854G>A | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.65 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038863 | c.1842G>T | synonymous_variant | 0.65 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.75 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038884 | c.1821C>T | synonymous_variant | 0.74 | pyrazinamide | |
clpC1 | 4038890 | c.1815G>A | synonymous_variant | 0.75 | pyrazinamide | |
panD | 4044872 | c.-591C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
glpK | 4138622 | c.1134C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R |