Run ID: dc33fbe6-4f71-417a-89be-9a269ab1f5b9
Sample name:
Date: 10-07-2023 12:23:00
Number of reads: 86912
Percentage reads mapped: 1.3
Median coverage: 0
Strain:
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage1.1.1 | Indo-Oceanic | RD239 | 0.79 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | rrs | n.799C>T | Uncertain significance | |
| amikacin | rrs | n.1401A>G | Assoc w R | |
| kanamycin | rrs | n.1401A>G | Assoc w R | |
| capreomycin | rrs | n.1401A>G | Assoc w R | |
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rrs | 1472644 | n.799C>T | non_coding_transcript_exon_variant | 0.91 | streptomycin | Uncertain significance | |
| rrs | 1473246 | n.1401A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Assoc w R | |
| capreomycin | Assoc w R | ||||||
| aminoglycosides | Uncertain significance | ||||||
| amikacin | Assoc w R |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762995 | c.-375G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763005 | p.Cys1067Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 763013 | c.-357C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763022 | c.-348C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763028 | c.-342T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763052 | c.-318G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763053 | c.-317T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763070 | c.-300T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763074 | p.Thr1090Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 763085 | c.-285C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763094 | c.-276G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763103 | c.-267G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763109 | c.-261C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763115 | c.-255T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763118 | p.Glu1104Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763578 | p.Phe70Tyr | missense_variant | 1.0 | rifampicin | |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.91 | rifampicin | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471925 | n.80_81insGCAGCTTG | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471928 | n.83T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471930 | n.88_89delGA | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1471978 | n.133C>T | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471996 | n.151C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472078 | n.233C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472123 | n.278A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472151 | n.306C>A | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472160 | n.315C>T | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472225 | n.380C>G | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472259 | n.414C>A | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472278 | n.433C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472279 | n.434T>C | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472285 | n.440A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472286 | n.441C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472289 | n.444T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472290 | n.445C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472324 | n.479G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472325 | n.480G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472328 | n.483G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472330 | n.485G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472435 | n.590T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472438 | n.593T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472439 | n.594C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472447 | n.602C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472448 | n.603T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472450 | n.605A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472451 | n.606C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472461 | n.616G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472462 | n.617T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472471 | n.626G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472484 | n.639A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472489 | n.644A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472494 | n.649A>G | non_coding_transcript_exon_variant | 0.99 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472558 | n.713G>A | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472569 | n.724G>A | non_coding_transcript_exon_variant | 0.88 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472607 | n.762G>A | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472612 | n.767G>T | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472660 | n.815T>C | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472685 | n.840G>T | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472686 | n.841G>C | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472687 | n.842A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472690 | n.845C>T | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.88 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472828 | n.983T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472836 | n.991G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472837 | n.992C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472841 | n.996G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472844 | n.999_1000insAG | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472847 | n.1004_1005delCT | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472873 | n.1028C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472874 | n.1029C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472878 | n.1033G>A | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472880 | n.1035G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472974 | n.1129A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472977 | n.1133dupT | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473080 | n.1235C>T | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473089 | n.1244A>C | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473091 | n.1246G>C | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473094 | n.1249T>A | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473099 | n.1254T>C | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473102 | n.1257C>T | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473120 | n.1275C>G | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473123 | n.1278A>G | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473132 | n.1287T>C | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473135 | n.1290C>T | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473285 | n.1442_1443delCC | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473292 | n.1447G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473293 | n.1448G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| rrl | 1473884 | n.227C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473888 | n.231T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473889 | n.232G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473896 | n.239C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473911 | n.254G>A | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474182 | n.525C>A | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| rrl | 1474183 | n.526T>G | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474185 | n.529delA | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474197 | n.540C>T | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| rrl | 1474200 | n.545delT | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1474253 | n.596A>T | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1474263 | n.606G>A | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 0.96 | linezolid | Uncertain significance |
| rrl | 1474310 | n.655delG | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474310 | n.654_655insT | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474351 | n.694G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474447 | n.790G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474451 | n.794T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474467 | n.810A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474487 | n.830G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474495 | n.838G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474496 | n.839C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474497 | n.840G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474498 | n.841G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474505 | n.848C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474506 | n.849C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474507 | n.850G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474508 | n.851C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474517 | n.860C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474527 | n.870T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474542 | n.885A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474601 | n.944C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474736 | n.1079C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474751 | n.1094G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474784 | n.1127C>T | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.99 | linezolid | |
| rrl | 1474798 | n.1141C>G | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1474825 | n.1168G>A | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474837 | n.1180A>G | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1474896 | n.1239A>G | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| rrl | 1474901 | n.1244A>G | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1474921 | n.1264C>T | non_coding_transcript_exon_variant | 0.96 | linezolid | Uncertain significance |
| rrl | 1475514 | n.1857G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475522 | n.1865A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475525 | n.1868G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475531 | n.1874C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475539 | n.1882A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475542 | n.1885A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475550 | n.1893A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475672 | n.2015C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475673 | n.2016T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475688 | n.2031G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475696 | n.2039T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475703 | n.2046A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475704 | n.2047C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475713 | n.2056C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1475883 | n.2226A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1475900 | n.2243A>G | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1475902 | n.2245T>C | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1475906 | n.2249C>T | non_coding_transcript_exon_variant | 0.98 | linezolid | Uncertain significance |
| rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1475997 | n.2340A>T | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1476025 | n.2368G>A | non_coding_transcript_exon_variant | 0.96 | linezolid | Uncertain significance |
| rrl | 1476029 | n.2372A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476032 | n.2375C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476035 | n.2378G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476036 | n.2379A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476043 | n.2386T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476044 | n.2387T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476045 | n.2388G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476047 | n.2390G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476080 | n.2423T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| rrl | 1476250 | n.2593C>G | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| rrl | 1476256 | n.2599A>G | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476262 | n.2605G>A | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476280 | n.2623A>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| rrl | 1476293 | n.2636C>T | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1476294 | n.2637A>G | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1476295 | n.2638C>G | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1476296 | n.2639C>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1476298 | n.2641C>A | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| rrl | 1476300 | n.2643G>T | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| rrl | 1476307 | n.2650A>T | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| rrl | 1476309 | n.2652G>T | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1476312 | n.2655T>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1476313 | n.2656G>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1476336 | n.2679C>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1476338 | n.2681C>T | non_coding_transcript_exon_variant | 0.21 | linezolid | Uncertain significance |
| rrl | 1476356 | n.2699C>G | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476357 | n.2700T>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476384 | n.2727G>C | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1476408 | n.2751G>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476411 | n.2754G>T | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| rrl | 1476442 | n.2785T>A | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| rrl | 1476535 | n.2878G>A | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.96 | linezolid | Uncertain significance |
| rrl | 1476540 | n.2883C>G | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1476573 | n.2916A>T | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| rrl | 1476607 | n.2950C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476624 | n.2967T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476630 | n.2973A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| clpC1 | 4038836 | c.1869G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039871 | p.Thr278Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039877 | c.828C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039889 | c.816G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide |
