TB-Profiler result

Run: SRR29051093
Summary

Run ID: SRR29051093

Sample name:

Date: 2025-02-11T14:13:14.348463

Number of reads: 168672

Percentage reads mapped: 45.53

Median coverage: 4.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.84
lineage1.2.1.2.1 Indo-Oceanic RD239 0.38
lineage4.9 Euro-American (H37Rv-like) None 0.85
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Leu359Ile Uncertain significance Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
embB 4247448 p.His312Arg missense_variant 0.8 ethambutol Mutation from literature
embB 4247588 p.Leu359Ile missense_variant 0.65 ethambutol Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
ccsA 619609 c.-282G>C upstream_gene_variant 0.73 kanamycin
capreomycin
amikacin
Rv0565c 657219 p.Ala84Val missense_variant 0.6 ethionamide
Rv0565c 657231 p.Ile80Val missense_variant 0.6 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 0.64 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.73 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.73 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.79 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.79 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.83 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.81 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.81 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.8 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.8 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.86 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.86 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.86 ethionamide
Rv0565c 657356 p.Ile39Val missense_variant 0.86 ethionamide
Rv0565c 657372 c.99G>C synonymous_variant 0.83 ethionamide
Rv0565c 657375 c.96C>T synonymous_variant 0.83 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.77 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
rpoB 760283 c.477G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.92 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.92 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.94 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.94 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.9 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.94 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.94 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.94 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.94 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.54 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.54 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.57 rifampicin Uncertain significance
rpoB 760661 c.855A>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.64 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.6 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.5 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.82 rifampicin
rpoB 761312 c.1506G>C synonymous_variant 0.9 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.83 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.84 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 0.88 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.88 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.88 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.94 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.94 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.93 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.87 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.87 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.87 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.87 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.9 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.94 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.88 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.89 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.89 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.88 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.87 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.87 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.83 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.86 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.89 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.91 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.9 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.95 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.95 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.94 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762413 c.2607G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 1.0 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 1.0 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 1.0 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 1.0 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 762521 c.-849C>T upstream_gene_variant 0.92 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.92 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.92 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.92 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.92 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.53 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.53 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.56 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.56 rifampicin Uncertain significance
rpoB 762810 p.Ala1002Ser missense_variant 0.61 rifampicin
rpoB 762813 p.Met1003Val missense_variant 0.61 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.96 rifampicin
rpoC 763013 c.-357C>G upstream_gene_variant 0.93 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.94 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.95 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.95 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.88 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.88 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.88 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.88 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.73 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.73 rifampicin
rpoC 763402 c.33C>G synonymous_variant 0.87 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.89 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.95 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.96 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.92 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.88 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.87 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.86 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.83 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.81 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.84 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.76 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.77 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.77 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.78 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.8 rifampicin
rpoC 763877 c.508_510delCTAinsTTG synonymous_variant 0.8 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.8 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.81 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.81 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 0.93 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.93 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.93 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.93 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.95 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.95 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.96 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.96 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.94 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.96 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.96 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.93 rifampicin Not assoc w R
rpoC 765019 c.1650A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.95 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765346 c.1977C>G synonymous_variant 0.71 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.71 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.79 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.8 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.97 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.93 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.92 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.92 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.96 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.96 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.96 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.96 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.96 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.96 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.96 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.96 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.96 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.96 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.96 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.94 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.94 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.94 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.93 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.96 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.96 rifampicin
rpoC 766030 c.2661C>G synonymous_variant 0.97 rifampicin
rpoC 766036 c.2667C>T synonymous_variant 0.97 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.97 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.94 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.88 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.93 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.92 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.9 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766168 c.2799C>T synonymous_variant 0.88 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 1.0 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 1.0 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 1.0 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 1.0 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.9 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.83 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.67 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.67 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.73 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.76 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.78 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.78 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.82 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.83 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.84 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.87 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.87 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.87 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.88 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.88 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.9 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.89 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.88 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.88 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.88 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.89 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.94 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.88 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.82 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.82 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.82 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.92 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 1.0 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpsL 781628 c.69T>C synonymous_variant 0.7 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.7 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.77 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.77 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.85 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.77 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.77 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.73 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.82 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.83 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.86 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.88 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.88 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.79 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.79 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.85 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.79 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.79 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.79 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.79 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.75 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.73 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.73 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.8 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.9 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.85 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.85 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.85 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.83 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.85 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.93 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.93 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.92 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.92 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.92 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.91 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.9 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.9 linezolid
rplC 801207 c.399C>T synonymous_variant 0.86 linezolid
rplC 801246 c.438C>T synonymous_variant 0.88 linezolid
rplC 801249 c.441T>C synonymous_variant 0.88 linezolid
rplC 801255 c.447C>T synonymous_variant 0.88 linezolid
rplC 801264 c.456C>T synonymous_variant 0.88 linezolid
rplC 801267 c.459A>T synonymous_variant 0.88 linezolid
rplC 801270 c.462T>C synonymous_variant 0.88 linezolid
rplC 801276 c.468G>C synonymous_variant 0.88 linezolid
rplC 801279 c.471G>C synonymous_variant 0.88 linezolid
rplC 801282 c.474G>C synonymous_variant 0.88 linezolid
rplC 801285 c.477G>C synonymous_variant 0.89 linezolid
rplC 801300 c.492C>G synonymous_variant 0.95 linezolid
rplC 801309 c.501C>G synonymous_variant 0.95 linezolid
rplC 801312 c.504G>C synonymous_variant 0.95 linezolid
rplC 801321 c.513C>T synonymous_variant 0.91 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.91 linezolid
rplC 801339 c.531T>C synonymous_variant 0.88 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.87 linezolid
rplC 801348 c.540T>G synonymous_variant 0.82 linezolid
rplC 801357 c.549T>C synonymous_variant 0.73 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.67 linezolid
rplC 801402 c.594T>C synonymous_variant 0.73 linezolid
rplC 801405 c.597T>C synonymous_variant 0.73 linezolid
rplC 801423 c.615G>C synonymous_variant 0.71 linezolid
rplC 801426 c.618C>G synonymous_variant 0.71 linezolid
rplC 801427 p.Met207Val missense_variant 0.71 linezolid
rplC 801438 c.630T>C synonymous_variant 0.65 linezolid
rplC 801442 p.Ile212Val missense_variant 0.68 linezolid
fbiC 1303681 c.751T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1303728 c.798G>A synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 0.75 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303761 c.831T>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1303797 c.867A>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303845 c.915C>G synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303914 c.984C>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304856 c.1926C>G synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1304883 p.Glu651Asp missense_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304891 p.Ile654Thr missense_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1304907 c.1977C>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1304983 c.2053C>T synonymous_variant 0.5 pretomanid
delamanid
clofazimine
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rpsA 1833589 c.48A>T synonymous_variant 0.85 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.85 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.86 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.94 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.95 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 1.0 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
ndh 2101912 c.1131G>C synonymous_variant 0.73 isoniazid
delamanid
ethionamide
ndh 2101920 c.1123A>C synonymous_variant 0.7 isoniazid
delamanid
ethionamide
ndh 2101924 c.1119T>G synonymous_variant 0.7 isoniazid
delamanid
ethionamide
ndh 2101939 c.1104A>G synonymous_variant 0.7 isoniazid
delamanid
ethionamide
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.91 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.91 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.8 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.83 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.87 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.87 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.87 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.93 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.93 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.93 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.93 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.94 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.94 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.94 isoniazid
kasA 2518768 c.654C>T synonymous_variant 1.0 isoniazid
kasA 2518777 c.663C>T synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>C synonymous_variant 1.0 isoniazid
kasA 2518792 c.678C>A synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518910 p.Leu266Met missense_variant 1.0 isoniazid
kasA 2518921 c.807T>C synonymous_variant 1.0 isoniazid
kasA 2518936 c.822C>G synonymous_variant 1.0 isoniazid
kasA 2518939 c.825T>C synonymous_variant 1.0 isoniazid
kasA 2518942 c.828T>C synonymous_variant 1.0 isoniazid
kasA 2518951 c.837G>C synonymous_variant 1.0 isoniazid
kasA 2518954 c.840C>G synonymous_variant 1.0 isoniazid
kasA 2518963 c.849T>C synonymous_variant 1.0 isoniazid
kasA 2518969 c.855T>G synonymous_variant 1.0 isoniazid
kasA 2518975 c.861C>G synonymous_variant 1.0 isoniazid
kasA 2518979 c.865A>C synonymous_variant 1.0 isoniazid
kasA 2518990 c.876T>G synonymous_variant 1.0 isoniazid
kasA 2518993 c.879C>G synonymous_variant 1.0 isoniazid
kasA 2518999 c.885G>C synonymous_variant 1.0 isoniazid
kasA 2519008 c.894C>G synonymous_variant 1.0 isoniazid
kasA 2519017 c.903G>C synonymous_variant 1.0 isoniazid
kasA 2519020 c.906G>C synonymous_variant 1.0 isoniazid
kasA 2519021 p.Ala303Lys missense_variant 1.0 isoniazid
kasA 2519027 p.Ile305Val missense_variant 1.0 isoniazid
kasA 2519050 c.936C>G synonymous_variant 1.0 isoniazid
kasA 2519053 c.939G>C synonymous_variant 1.0 isoniazid
kasA 2519056 c.942G>C synonymous_variant 1.0 isoniazid
kasA 2519062 c.948T>G synonymous_variant 1.0 isoniazid
kasA 2519068 c.954C>T synonymous_variant 1.0 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 1.0 isoniazid
kasA 2519095 c.981C>A synonymous_variant 1.0 isoniazid
kasA 2519107 c.993T>C synonymous_variant 1.0 isoniazid
kasA 2519108 p.Asp332Gln missense_variant 1.0 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 1.0 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 1.0 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.9 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.92 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.92 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.86 isoniazid
kasA 2519196 p.Thr361Ser missense_variant 0.85 isoniazid
Rv2477c 2782869 p.Ala392Thr missense_variant 0.8 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783521 c.522G>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.92 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783557 c.486T>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.96 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2752c 3066002 p.Met64Leu missense_variant 0.62 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066009 c.183G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>G synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 0.58 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066042 c.150T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066045 c.147T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.67 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.67 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 c.126T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066074 c.118C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066102 c.90C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067316 c.630A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067328 c.618G>A synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.92 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.88 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.81 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.88 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.88 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.89 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.9 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.88 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.92 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.96 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067691 p.Ile85Leu missense_variant 0.95 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067736 p.Phe70Leu missense_variant 0.94 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.95 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.95 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.73 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.69 para-aminosalicylic_acid
lpqB 3624722 c.189C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3625149 p.Val489Ile missense_variant 0.8 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625165 c.-255G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625186 c.-276T>C upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3625189 c.1425A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.9 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrB 3627065 c.-452G>C upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627071 c.279G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627074 c.-461G>C upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.78 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrA 3627221 c.129C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTA upstream_gene_variant 0.9 rifampicin
bedaquiline
rpoA 3877553 p.Glu319Gln missense_variant 1.0 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.88 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.88 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.87 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.86 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.82 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.8 rifampicin
clpC1 4038293 c.2412G>C synonymous_variant 0.77 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.77 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 0.83 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.83 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.83 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.85 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.83 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.82 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 1.0 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.95 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.89 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.84 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.82 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.82 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.63 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.67 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.78 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.81 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.81 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.79 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.94 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.94 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.85 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.87 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.76 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.82 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.78 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4039988 c.717C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.79 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.82 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.81 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.8 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.67 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.71 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040342 c.363C>G synonymous_variant 0.75 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.85 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.86 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.85 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.91 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.91 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.92 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.81 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.87 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.81 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.81 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.81 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.69 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.69 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.69 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.69 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
embA 4245248 c.2016G>C synonymous_variant 0.82 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.82 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embA 4245282 p.Ile684Val missense_variant 0.8 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.8 ethambutol
embA 4245290 c.2058C>G synonymous_variant 0.8 ethambutol
embA 4245293 c.2061T>G synonymous_variant 0.8 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.8 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.8 ethambutol
embB 4245701 c.-813G>C upstream_gene_variant 0.8 ethambutol
embB 4245704 c.-810G>C upstream_gene_variant 0.8 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.86 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.86 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.88 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.82 ethambutol
embB 4246184 c.-330A>C upstream_gene_variant 0.69 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 0.71 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.71 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.67 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.73 ethambutol
embA 4246227 p.Ile999Val missense_variant 0.75 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.79 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.75 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.8 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.86 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.87 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.87 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.87 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.87 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.87 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.87 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.87 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.64 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.86 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.86 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.86 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.8 ethambutol
embB 4247446 c.933C>T synonymous_variant 0.8 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.82 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.83 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.76 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.81 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.71 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.75 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.74 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.67 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.65 ethambutol
embB 4247578 c.1065G>A synonymous_variant 0.35 ethambutol Not assoc w R
embB 4247579 p.Ala356Phe missense_variant 0.65 ethambutol
embB 4247587 c.1074G>A synonymous_variant 0.65 ethambutol
embB 4247603 c.1090C>T synonymous_variant 0.69 ethambutol
embB 4247611 c.1098G>T synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4247614 c.1101T>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.62 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.62 ethambutol
embB 4247638 c.1125G>T synonymous_variant 0.67 ethambutol
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
embB 4247797 c.1284C>G synonymous_variant 0.87 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.88 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.88 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.87 ethambutol
embB 4247819 p.Val436Ile missense_variant 0.93 ethambutol Uncertain significance
embB 4247830 c.1317A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.94 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.93 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.93 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.93 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.93 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.82 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.82 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.81 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.79 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.75 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.75 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.73 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.81 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.87 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.86 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.87 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.87 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.83 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.83 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.83 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.91 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.93 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.93 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.81 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.77 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.8 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.84 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.84 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.83 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.83 ethambutol Uncertain significance
embB 4248220 c.1707A>C synonymous_variant 0.84 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.92 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.82 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.8 ethambutol
embB 4249444 c.2931T>C synonymous_variant 0.8 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.73 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.67 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.7 ethambutol
aftB 4268096 c.741C>G synonymous_variant 0.92 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.92 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4268117 c.720G>C synonymous_variant 0.87 ethambutol
aftB 4268123 p.Ser238Gly missense_variant 0.87 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.88 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.88 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.88 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.94 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.94 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.94 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4268182 p.Phe219Leu missense_variant 0.94 ethambutol
aftB 4268183 c.654A>T synonymous_variant 0.94 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.93 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.93 ethambutol
aftB 4268213 c.624T>G synonymous_variant 0.93 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.92 ethambutol