TB-Profiler result

Run: ERR3797019

Summary

Run ID: ERR3797019

Sample name:

Date: 01-04-2023 03:02:39

Number of reads: 3313836

Percentage reads mapped: 80.31

Strain: La1.8.1

Drug-resistance: Other


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
La1 M.bovis None None 0.99
La1.8 M.bovis None None 1.0
La1.8.1 M.bovis None None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrB 6172 c.933C>T synonymous_variant 0.15
gyrB 6196 c.957C>G synonymous_variant 0.16
gyrB 6202 c.963C>T synonymous_variant 0.17
gyrB 6203 p.Ser322Ala missense_variant 0.17
gyrB 6242 p.Arg335Lys missense_variant 0.21
gyrB 6250 c.1011A>G synonymous_variant 0.2
gyrB 6253 c.1014G>C synonymous_variant 0.21
gyrB 6259 p.Asp340Glu missense_variant 0.21
gyrB 6268 c.1029C>G synonymous_variant 0.22
gyrB 6286 c.1047T>C synonymous_variant 0.23
gyrB 6292 c.1053G>C synonymous_variant 0.19
gyrB 6295 c.1056A>G synonymous_variant 0.16
gyrB 6298 c.1059C>A synonymous_variant 0.14
gyrB 6301 c.1062G>C synonymous_variant 0.13
gyrA 6307 c.-995T>G upstream_gene_variant 0.15
gyrA 6310 c.-992G>C upstream_gene_variant 0.13
gyrA 6406 c.-896C>T upstream_gene_variant 0.98
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 6634 c.-668T>C upstream_gene_variant 0.23
gyrA 6637 c.-665T>G upstream_gene_variant 0.24
gyrA 6640 c.-662A>C upstream_gene_variant 0.22
gyrA 6643 c.-659A>G upstream_gene_variant 0.21
gyrA 6649 c.-653T>C upstream_gene_variant 0.26
gyrA 6652 c.-650C>G upstream_gene_variant 0.26
gyrA 6655 c.-647T>C upstream_gene_variant 0.27
gyrA 6673 c.-629A>T upstream_gene_variant 0.26
gyrA 6700 c.-602T>C upstream_gene_variant 0.24
gyrA 6703 c.-599G>C upstream_gene_variant 0.23
gyrA 6709 c.-593A>G upstream_gene_variant 0.24
gyrA 6712 c.-590G>C upstream_gene_variant 0.24
gyrA 6724 c.-578G>C upstream_gene_variant 0.24
gyrA 6730 c.-572A>C upstream_gene_variant 0.28
gyrA 6745 c.-557T>C upstream_gene_variant 0.21
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7715 c.414G>C synonymous_variant 0.13
gyrA 7730 p.Arg143Ser missense_variant 0.14
gyrA 8048 c.747C>A synonymous_variant 0.99
gyrA 8189 c.888G>C synonymous_variant 0.13
gyrA 8190 p.Ala297Thr missense_variant 0.13
gyrA 8198 c.897T>C synonymous_variant 0.14
gyrA 8201 c.900C>G synonymous_variant 0.14
gyrA 8207 c.906T>C synonymous_variant 0.14
gyrA 8219 c.918T>C synonymous_variant 0.17
gyrA 8228 c.927G>T synonymous_variant 0.18
gyrA 8234 c.933T>C synonymous_variant 0.17
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.18
gyrA 8246 c.945C>G synonymous_variant 0.18
gyrA 8247 p.Ile316Val missense_variant 0.18
gyrA 8253 p.Ile318Val missense_variant 0.2
gyrA 8264 c.963T>C synonymous_variant 0.2
gyrA 8267 c.966G>C synonymous_variant 0.19
gyrA 8283 p.Ile328Leu missense_variant 0.17
gyrA 8288 c.987T>C synonymous_variant 0.16
gyrA 8294 c.993T>C synonymous_variant 0.17
gyrA 8324 c.1023T>C synonymous_variant 0.16
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9217 p.Asp639Ala missense_variant 0.98
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 760184 c.378A>G synonymous_variant 0.2
rpoB 760196 c.390C>G synonymous_variant 0.22
rpoB 760235 c.429T>C synonymous_variant 0.17
rpoB 760244 c.438G>C synonymous_variant 0.17
rpoB 760253 c.447T>C synonymous_variant 0.16
rpoB 760283 c.477G>C synonymous_variant 0.22
rpoB 760298 c.492G>C synonymous_variant 0.23
rpoB 760310 c.504G>C synonymous_variant 0.21
rpoB 760316 c.510C>G synonymous_variant 0.19
rpoB 760328 c.522G>C synonymous_variant 0.14
rpoB 760331 c.525G>T synonymous_variant 0.14
rpoB 760334 c.528G>C synonymous_variant 0.14
rpoB 760340 c.534G>T synonymous_variant 0.15
rpoB 760356 p.Thr184Ser missense_variant 0.15
rpoB 760361 c.555T>C synonymous_variant 0.16
rpoB 760370 c.564C>G synonymous_variant 0.15
rpoB 760373 c.567C>G synonymous_variant 0.15
rpoB 760376 p.Asp190Glu missense_variant 0.17
rpoB 760400 c.594G>C synonymous_variant 0.18
rpoB 760406 c.600G>C synonymous_variant 0.16
rpoB 760407 p.Ser201Gly missense_variant 0.17
rpoB 760424 c.618C>G synonymous_variant 0.16
rpoB 760430 c.624T>C synonymous_variant 0.16
rpoB 760457 c.651C>T synonymous_variant 0.15
rpoB 760460 c.654G>C synonymous_variant 0.17
rpoB 760475 c.669A>G synonymous_variant 0.21
rpoB 760481 c.675G>T synonymous_variant 0.21
rpoB 760484 c.678A>G synonymous_variant 0.23
rpoB 760487 c.681G>C synonymous_variant 0.19
rpoB 760511 c.705G>C synonymous_variant 0.15
rpoB 760522 p.Ser239Asn missense_variant 0.19
rpoB 760532 c.726T>C synonymous_variant 0.17
rpoB 760535 c.729C>G synonymous_variant 0.13
rpoB 760541 c.735G>C synonymous_variant 0.13
rpoB 760547 c.741G>C synonymous_variant 0.16
rpoB 761015 c.1209G>C synonymous_variant 0.14
rpoB 761027 c.1221A>G synonymous_variant 0.16
rpoB 761036 c.1230G>C synonymous_variant 0.17
rpoB 761037 c.1231T>C synonymous_variant 0.17
rpoB 761051 c.1245G>T synonymous_variant 0.16
rpoB 761054 c.1248G>C synonymous_variant 0.16
rpoB 761057 c.1251G>C synonymous_variant 0.16
rpoB 761060 c.1254C>G synonymous_variant 0.16
rpoB 761063 c.1257C>G synonymous_variant 0.16
rpoB 761075 c.1269G>A synonymous_variant 0.17
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.15
rpoB 761102 c.1296A>G synonymous_variant 0.15
rpoB 761132 c.1326G>T synonymous_variant 0.15
rpoB 761133 c.1327T>C synonymous_variant 0.15
rpoB 761147 c.1341C>T synonymous_variant 0.15
rpoB 762143 c.2337T>C synonymous_variant 0.13
rpoB 762149 c.2343G>C synonymous_variant 0.13
rpoB 762158 c.2352G>C synonymous_variant 0.13
rpoB 762167 c.2361T>C synonymous_variant 0.13
rpoB 762176 c.2370T>C synonymous_variant 0.15
rpoB 762185 c.2379G>C synonymous_variant 0.14
rpoB 762218 c.2412T>C synonymous_variant 0.14
rpoB 762362 p.Glu852Asp missense_variant 0.16
rpoB 762369 c.2563T>C synonymous_variant 0.15
rpoC 762374 c.-996G>C upstream_gene_variant 0.16
rpoC 762395 c.-975G>C upstream_gene_variant 0.13
rpoC 762401 c.-969G>C upstream_gene_variant 0.14
rpoC 762404 c.-966T>C upstream_gene_variant 0.17
rpoC 762410 c.-960T>C upstream_gene_variant 0.17
rpoC 762416 c.-954A>G upstream_gene_variant 0.18
rpoC 762434 c.-936T>C upstream_gene_variant 0.19
rpoC 762443 c.-927G>C upstream_gene_variant 0.18
rpoC 762449 c.-921C>A upstream_gene_variant 0.18
rpoC 762452 c.-918G>C upstream_gene_variant 0.18
rpoC 762470 c.-900G>C upstream_gene_variant 0.18
rpoC 762491 c.-879T>C upstream_gene_variant 0.14
rpoC 763031 c.-339T>C upstream_gene_variant 0.99
rpoC 763040 c.-330C>G upstream_gene_variant 0.14
rpoC 763053 c.-317T>C upstream_gene_variant 0.14
rpoC 763070 c.-300T>C upstream_gene_variant 0.14
rpoC 763115 c.-255T>C upstream_gene_variant 0.14
rpoC 763166 c.-204A>G upstream_gene_variant 0.15
rpoC 763468 c.99G>C synonymous_variant 0.19
rpoC 763486 c.117T>C synonymous_variant 0.2
rpoC 763492 c.123G>A synonymous_variant 0.18
rpoC 763528 c.159G>A synonymous_variant 0.23
rpoC 763531 c.162G>T synonymous_variant 0.25
rpoC 763546 c.177A>G synonymous_variant 0.18
rpoC 763570 c.201G>C synonymous_variant 0.16
rpoC 763573 c.204G>C synonymous_variant 0.19
rpoC 763576 c.207C>G synonymous_variant 0.17
rpoC 763594 c.225C>T synonymous_variant 0.17
rpoC 763621 c.252C>T synonymous_variant 0.15
rpoC 763675 c.306C>G synonymous_variant 0.13
rpoC 763702 c.333C>G synonymous_variant 0.14
rpoC 763709 c.340C>T synonymous_variant 0.14
rpoC 763714 c.345G>C synonymous_variant 0.14
rpoC 763717 c.348T>C synonymous_variant 0.14
rpoC 763723 c.354G>C synonymous_variant 0.14
rpoC 763732 c.363C>T synonymous_variant 0.15
rpoC 763741 c.372C>T synonymous_variant 0.16
rpoC 763744 c.375G>C synonymous_variant 0.15
rpoC 763765 c.396T>G synonymous_variant 0.15
rpoC 763771 c.402C>T synonymous_variant 0.15
rpoC 763781 p.Ser138Ala missense_variant 0.15
rpoC 763787 p.Asp140Asn missense_variant 0.14
rpoC 763792 p.Glu141Asp missense_variant 0.16
rpoC 763807 c.438T>C synonymous_variant 0.15
rpoC 763813 c.444C>G synonymous_variant 0.14
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.14
rpoC 764434 c.1065A>G synonymous_variant 0.14
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.15
rpoC 764446 c.1077T>C synonymous_variant 0.16
rpoC 764449 c.1080G>C synonymous_variant 0.15
rpoC 764452 c.1083T>C synonymous_variant 0.15
rpoC 764458 c.1089G>C synonymous_variant 0.15
rpoC 764461 c.1092A>G synonymous_variant 0.17
rpoC 764485 c.1116G>C synonymous_variant 0.16
rpoC 764491 c.1122G>T synonymous_variant 0.14
rpoC 764497 c.1128A>G synonymous_variant 0.14
rpoC 764500 c.1131C>G synonymous_variant 0.14
rpoC 764521 c.1152T>C synonymous_variant 0.16
rpoC 764527 c.1158C>G synonymous_variant 0.16
rpoC 764551 c.1182G>C synonymous_variant 0.13
rpoC 764575 c.1206T>G synonymous_variant 0.16
rpoC 764605 c.1236G>C synonymous_variant 0.15
rpoC 764611 c.1242G>T synonymous_variant 0.19
rpoC 764626 c.1257C>T synonymous_variant 0.19
rpoC 764632 c.1263T>C synonymous_variant 0.17
rpoC 764650 c.1281G>T synonymous_variant 0.19
rpoC 764713 c.1344G>T synonymous_variant 0.19
rpoC 764716 c.1347G>C synonymous_variant 0.19
rpoC 764746 c.1377G>T synonymous_variant 0.18
rpoC 764752 c.1383G>C synonymous_variant 0.19
rpoC 764758 c.1389C>G synonymous_variant 0.17
rpoC 764764 c.1395T>C synonymous_variant 0.15
rpoC 764797 c.1428G>C synonymous_variant 0.15
rpoC 764803 c.1434C>T synonymous_variant 0.13
rpoC 764809 c.1440C>T synonymous_variant 0.14
rpoC 764827 c.1458G>C synonymous_variant 0.16
rpoC 764843 p.Ala492Ser missense_variant 0.18
rpoC 764858 c.1489T>C synonymous_variant 0.15
rpoC 764875 c.1506C>A synonymous_variant 0.15
rpoC 764887 c.1518G>C synonymous_variant 0.13
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 0.14
rpoC 764911 c.1542A>G synonymous_variant 0.14
rpoC 764912 p.Met515Gln missense_variant 0.14
rpoC 764923 c.1554A>G synonymous_variant 0.16
rpoC 764935 c.1566T>C synonymous_variant 0.18
rpoC 764948 c.1579T>C synonymous_variant 0.16
rpoC 764953 c.1584G>C synonymous_variant 0.15
rpoC 764968 c.1599T>C synonymous_variant 0.13
rpoC 765892 c.2523T>C synonymous_variant 0.13
rpoC 765898 c.2529C>T synonymous_variant 0.13
rpoC 765904 c.2535C>G synonymous_variant 0.14
rpoC 765937 c.2568T>C synonymous_variant 0.14
rpoC 766804 c.3435A>G synonymous_variant 0.16
rpoC 767098 c.3729T>C synonymous_variant 0.16
rpoC 767104 c.3735C>G synonymous_variant 0.16
rpoC 767105 p.Asn1246Gln missense_variant 0.14
rpoC 767119 c.3750A>G synonymous_variant 0.2
rpoC 767149 c.3780C>A synonymous_variant 0.16
rpoC 767152 c.3783T>C synonymous_variant 0.14
rpoC 767158 c.3789T>C synonymous_variant 0.15
rpoC 767167 c.3798C>G synonymous_variant 0.16
rpoC 767180 p.Ala1271Gln missense_variant 0.15
rpoC 767191 c.3822C>G synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781802 c.243G>C synonymous_variant 0.15
rpsL 781814 c.255C>T synonymous_variant 0.17
rpsL 781817 c.258G>T synonymous_variant 0.17
rpsL 781829 c.270G>C synonymous_variant 0.18
rpsL 781832 c.273T>C synonymous_variant 0.17
rpsL 781835 c.276T>C synonymous_variant 0.16
rpsL 781859 c.300T>C synonymous_variant 0.19
rpsL 781868 c.309T>C synonymous_variant 0.22
rpsL 781871 c.312G>C synonymous_variant 0.22
rpsL 781877 c.318T>C synonymous_variant 0.2
rpsL 781892 c.333A>G synonymous_variant 0.2
rpsL 781895 c.336G>A synonymous_variant 0.17
rpsL 781898 c.339A>C synonymous_variant 0.18
rpsL 781916 c.357T>G synonymous_variant 0.2
rpsL 781929 p.Gly124Ser missense_variant 0.2
rplC 801454 p.Glu216Gln missense_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471935 n.90T>C non_coding_transcript_exon_variant 0.87
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.13
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.14
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.25
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.31
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.17
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.15
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.16
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.19
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.17
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.18
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.18
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.2
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.2
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.23
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.21
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.21
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.22
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.24
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.54
rrs 1472847 n.1002G>T non_coding_transcript_exon_variant 0.46
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.44
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.44
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.46
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.46
rrs 1472860 n.1015C>A non_coding_transcript_exon_variant 0.46
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.47
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.44
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.38
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.32
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.61
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.66
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.68
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.46
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.42
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.13
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.15
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.26
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.31
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.36
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.26
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.25
rrl 1473813 n.156C>A non_coding_transcript_exon_variant 0.27
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.25
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.25
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.22
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.22
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.26
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.23
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.27
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.2
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.18
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.18
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.22
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.13
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.15
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.33
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.33
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.32
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.27
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.26
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.27
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.29
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.28
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.22
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.22
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.26
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.41
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.36
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.36
rrl 1474630 n.973T>G non_coding_transcript_exon_variant 0.36
rrl 1474631 n.974G>T non_coding_transcript_exon_variant 0.38
rrl 1474636 n.979A>G non_coding_transcript_exon_variant 0.4
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.4
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.4
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.4
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.35
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.33
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.31
rrl 1474718 n.1061A>T non_coding_transcript_exon_variant 0.27
rrl 1474720 n.1065_1066delTG non_coding_transcript_exon_variant 0.29
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.27
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.23
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.22
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.19
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.2
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.17
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.2
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.25
rrl 1475324 n.1667G>A non_coding_transcript_exon_variant 0.29
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.38
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.38
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.37
rrl 1475376 n.1719A>C non_coding_transcript_exon_variant 0.35
rrl 1475380 n.1723C>T non_coding_transcript_exon_variant 0.37
rrl 1475387 n.1730C>T non_coding_transcript_exon_variant 0.38
rrl 1475397 n.1740G>A non_coding_transcript_exon_variant 0.4
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.41
rrl 1475403 n.1746T>G non_coding_transcript_exon_variant 0.41
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.44
rrl 1475406 n.1749T>G non_coding_transcript_exon_variant 0.46
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.5
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.54
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.54
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.53
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.5
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.44
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.41
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.47
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.41
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.46
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.46
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.29
rrl 1475603 n.1946G>A non_coding_transcript_exon_variant 0.29
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.29
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.33
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.3
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 0.3
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 0.3
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 0.33
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.3
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.3
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.32
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.33
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.33
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.36
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.58
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.59
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.5
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.52
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.52
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.5
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.32
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.32
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.32
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.32
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.32
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.37
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.33
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.32
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.32
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.4
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.38
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.37
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.37
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.37
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.35
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.33
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.36
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.38
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.38
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.45
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.44
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.44
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.44
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.45
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.51
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.49
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.5
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.4
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.31
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.35
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.33
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.33
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.35
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.41
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.35
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.38
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.42
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.39
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.43
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.34
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.31
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.3
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.18
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.27
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 0.14
rrl 1476744 n.3087G>A non_coding_transcript_exon_variant 0.14
rrl 1476746 n.3089T>A non_coding_transcript_exon_variant 0.16
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.2
rrl 1476755 n.3098G>T non_coding_transcript_exon_variant 0.16
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.24
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.14
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.14
inhA 1673715 c.-487C>G upstream_gene_variant 0.9
rpsA 1833829 c.288A>G synonymous_variant 0.14
rpsA 1833841 c.300C>G synonymous_variant 0.14
rpsA 1833847 c.306C>G synonymous_variant 0.14
rpsA 1833856 c.315A>G synonymous_variant 0.14
rpsA 1833862 c.321G>T synonymous_variant 0.13
rpsA 1833868 c.327C>T synonymous_variant 0.13
rpsA 1833892 c.351G>A synonymous_variant 0.13
rpsA 1833894 p.Ala118Glu missense_variant 0.13
rpsA 1833928 c.387G>C synonymous_variant 0.13
rpsA 1833949 c.408T>C synonymous_variant 0.14
rpsA 1833970 c.429G>C synonymous_variant 0.16
rpsA 1833979 c.438T>C synonymous_variant 0.16
rpsA 1833988 c.447C>T synonymous_variant 0.14
rpsA 1833991 c.450C>A synonymous_variant 0.14
rpsA 1834213 c.672G>C synonymous_variant 0.14
rpsA 1834234 c.693G>C synonymous_variant 0.13
rpsA 1834249 c.708T>C synonymous_variant 0.13
rpsA 1834303 c.762T>G synonymous_variant 0.14
rpsA 1834306 c.765T>C synonymous_variant 0.15
rpsA 1834348 c.807T>C synonymous_variant 0.15
rpsA 1834396 c.855G>C synonymous_variant 0.12
rpsA 1834859 p.Ala440Thr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103173 c.-132delG upstream_gene_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156025 c.87C>A synonymous_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168011 p.Ser868Arg missense_variant 1.0
PPE35 2168319 p.Thr765Ile missense_variant 1.0
PPE35 2168814 c.1798dupA frameshift_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 0.98
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
eis 2715125 p.Thr70Ala missense_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
Rv3083 3448783 p.Val94Ile missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474427 p.Val141Ile missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
rpoA 3877638 c.870T>C synonymous_variant 0.14
rpoA 3877656 c.852T>G synonymous_variant 0.15
rpoA 3877662 c.846C>T synonymous_variant 0.16
rpoA 3877668 c.840A>G synonymous_variant 0.16
rpoA 3877671 c.837C>G synonymous_variant 0.15
rpoA 3877677 c.831G>C synonymous_variant 0.16
rpoA 3877680 c.828G>C synonymous_variant 0.16
rpoA 3877686 c.822A>G synonymous_variant 0.17
rpoA 3877692 c.816G>C synonymous_variant 0.15
rpoA 3877704 c.804G>T synonymous_variant 0.18
rpoA 3877710 c.798C>T synonymous_variant 0.16
rpoA 3877731 c.777G>T synonymous_variant 0.17
rpoA 3877743 c.765T>C synonymous_variant 0.18
rpoA 3877764 c.744C>G synonymous_variant 0.13
rpoA 3877900 p.Ser203Thr missense_variant 0.13
rpoA 3877905 c.603A>G synonymous_variant 0.13
rpoA 3877908 c.600T>C synonymous_variant 0.13
rpoA 3878187 c.321C>G synonymous_variant 0.14
rpoA 3878193 c.315T>C synonymous_variant 0.14
rpoA 3878202 c.306G>C synonymous_variant 0.17
rpoA 3878205 c.303T>A synonymous_variant 0.17
rpoA 3878217 c.291A>G synonymous_variant 0.2
rpoA 3878247 c.261G>C synonymous_variant 0.22
rpoA 3878253 c.255G>C synonymous_variant 0.22
rpoA 3878259 c.249G>C synonymous_variant 0.21
rpoA 3878264 p.Ser82Gly missense_variant 0.21
rpoA 3878271 c.237T>C synonymous_variant 0.24
rpoA 3878283 p.Glu75Asp missense_variant 0.19
rpoA 3878292 c.216T>C synonymous_variant 0.22
rpoA 3878298 c.210A>G synonymous_variant 0.21
rpoA 3878310 c.198G>C synonymous_variant 0.18
rpoA 3878313 c.195G>C synonymous_variant 0.19
rpoA 3878322 c.186A>G synonymous_variant 0.2
rpoA 3878331 c.177A>G synonymous_variant 0.18
rpoA 3878337 c.171T>C synonymous_variant 0.18
rpoA 3878346 c.162T>C synonymous_variant 0.16
rpoA 3878630 c.-124delC upstream_gene_variant 1.0
clpC1 4038403 c.2302T>C synonymous_variant 1.0
clpC1 4038914 c.1791G>C synonymous_variant 0.13
clpC1 4038923 c.1782A>G synonymous_variant 0.17
clpC1 4038953 c.1752A>G synonymous_variant 0.19
clpC1 4038956 c.1749T>C synonymous_variant 0.19
clpC1 4038965 c.1740T>C synonymous_variant 0.2
clpC1 4038971 c.1734T>C synonymous_variant 0.19
clpC1 4038974 c.1731T>C synonymous_variant 0.2
clpC1 4038989 c.1716T>C synonymous_variant 0.16
clpC1 4038997 c.1708T>C synonymous_variant 0.14
clpC1 4039022 c.1683A>G synonymous_variant 0.16
clpC1 4039064 c.1641C>G synonymous_variant 0.14
clpC1 4039085 c.1620A>G synonymous_variant 0.15
clpC1 4039103 c.1602T>C synonymous_variant 0.15
clpC1 4039106 c.1599G>C synonymous_variant 0.15
clpC1 4039112 c.1593C>G synonymous_variant 0.15
clpC1 4039121 c.1584T>C synonymous_variant 0.15
clpC1 4039136 c.1569C>T synonymous_variant 0.16
clpC1 4039142 c.1563A>G synonymous_variant 0.16
clpC1 4039145 c.1560G>C synonymous_variant 0.18
clpC1 4039169 p.Glu512Asp missense_variant 0.17
clpC1 4039172 c.1533A>G synonymous_variant 0.16
clpC1 4039178 c.1527G>C synonymous_variant 0.16
clpC1 4039181 c.1522_1524delTTGinsCTC synonymous_variant 0.15
clpC1 4039187 c.1518G>T synonymous_variant 0.14
clpC1 4039190 c.1515C>G synonymous_variant 0.14
clpC1 4039199 p.Ala502Glu missense_variant 0.16
clpC1 4039208 c.1497C>G synonymous_variant 0.17
clpC1 4039226 c.1479T>C synonymous_variant 0.13
clpC1 4039244 c.1461G>C synonymous_variant 0.12
clpC1 4039286 c.1419T>C synonymous_variant 0.13
clpC1 4039298 c.1407T>C synonymous_variant 0.16
clpC1 4039310 c.1395A>G synonymous_variant 0.15
clpC1 4039313 c.1392C>T synonymous_variant 0.14
clpC1 4039319 c.1386T>C synonymous_variant 0.15
clpC1 4039322 c.1383T>C synonymous_variant 0.15
clpC1 4039328 c.1377A>G synonymous_variant 0.15
clpC1 4039334 c.1371G>C synonymous_variant 0.16
clpC1 4039337 c.1368A>C synonymous_variant 0.14
clpC1 4039347 p.Arg453Lys missense_variant 0.14
clpC1 4039382 c.1323C>G synonymous_variant 0.14
clpC1 4039430 c.1275T>C synonymous_variant 0.14
clpC1 4039517 c.1188C>G synonymous_variant 0.14
clpC1 4039541 c.1164C>G synonymous_variant 0.14
clpC1 4039577 c.1128T>C synonymous_variant 0.13
clpC1 4039586 c.1119G>C synonymous_variant 0.13
clpC1 4039592 c.1113G>C synonymous_variant 0.14
clpC1 4039616 c.1089G>C synonymous_variant 0.19
clpC1 4039622 c.1083C>T synonymous_variant 0.17
clpC1 4039979 c.726C>G synonymous_variant 0.13
clpC1 4040009 c.696C>G synonymous_variant 0.14
embC 4240671 p.Thr270Ile missense_variant 0.99
embC 4242642 p.Arg927His missense_variant 1.0
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 0.99
embB 4246551 p.Asn13Ser missense_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4248734 p.Arg741Trp missense_variant 1.0
aftB 4267167 p.Gln557Pro missense_variant 1.0
aftB 4267858 p.Ile327Val missense_variant 1.0
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4326024 p.Pro484Ser missense_variant 0.99
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0