TB-Profiler result

Run: SRR6832644
Summary

Run ID: SRR6832644

Sample name:

Date: 04-04-2023 17:33:18

Number of reads: 359064

Percentage reads mapped: 14.69

Strain: lineage4.3.3

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.87 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5451 p.Glu71Val missense_variant 0.33
gyrB 6302 p.Ala355Ser missense_variant 0.22
gyrB 6576 c.1339delT frameshift_variant 0.4
gyrB 6796 p.Ile519Met missense_variant 0.29
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 760422 c.616_618delCTCinsTTG synonymous_variant 0.25
rpoB 760466 c.660C>T synonymous_variant 0.33
rpoB 760475 c.669A>G synonymous_variant 0.3
rpoB 760481 c.675G>C synonymous_variant 0.3
rpoB 760484 c.678A>G synonymous_variant 0.3
rpoB 760490 c.684C>A synonymous_variant 0.3
rpoB 760502 c.696C>T synonymous_variant 0.33
rpoB 760508 c.702G>A synonymous_variant 0.33
rpoB 760519 p.Thr238Ser missense_variant 0.38
rpoB 761152 p.Leu449Gln missense_variant 0.2
rpoB 761594 c.1788C>T synonymous_variant 0.33
rpoB 761969 c.2163G>A synonymous_variant 0.33
rpoB 761990 c.2184G>C synonymous_variant 0.3
rpoB 761998 c.2193_2195delGTC disruptive_inframe_deletion 0.3
rpoB 762005 c.2200_2201insAGC disruptive_inframe_insertion 0.43
rpoB 762009 p.Leu735Ile missense_variant 0.43
rpoB 762014 c.2208C>G synonymous_variant 0.38
rpoB 762024 p.Val740Ile missense_variant 0.33
rpoB 762029 c.2223C>G synonymous_variant 0.33
rpoB 762035 c.2229G>C synonymous_variant 0.27
rpoB 762036 p.Ile744Val missense_variant 0.25
rpoB 762053 c.2247T>C synonymous_variant 0.25
rpoB 762065 c.2259T>C synonymous_variant 0.18
rpoB 762112 p.Asn769Ser missense_variant 0.22
rpoB 762143 c.2337T>C synonymous_variant 0.72
rpoB 762149 c.2343G>C synonymous_variant 0.76
rpoB 762156 p.Val784Ile missense_variant 0.75
rpoB 762173 p.Glu789Asp missense_variant 0.71
rpoB 762176 c.2370T>C synonymous_variant 0.74
rpoB 762181 p.Asp792Ala missense_variant 0.75
rpoB 762185 c.2379G>C synonymous_variant 0.75
rpoB 762191 c.2385C>T synonymous_variant 0.78
rpoB 762197 c.2391C>G synonymous_variant 0.8
rpoB 762200 c.2394C>T synonymous_variant 0.8
rpoB 762233 c.2427G>C synonymous_variant 0.87
rpoB 762242 c.2436G>A synonymous_variant 0.78
rpoB 762245 c.2439G>C synonymous_variant 0.78
rpoB 762254 c.2448T>C synonymous_variant 0.76
rpoB 762257 c.2451C>G synonymous_variant 0.77
rpoB 762266 c.2460T>C synonymous_variant 0.75
rpoB 762284 c.2478G>T synonymous_variant 0.77
rpoB 762290 c.2484C>T synonymous_variant 0.7
rpoB 762293 c.2487T>C synonymous_variant 0.7
rpoB 762296 c.2490G>C synonymous_variant 0.6
rpoB 762297 p.Leu831Met missense_variant 0.6
rpoC 762962 c.-408C>T upstream_gene_variant 0.53
rpoC 762971 c.-399G>C upstream_gene_variant 0.6
rpoC 762989 c.-381G>C upstream_gene_variant 0.67
rpoC 762995 c.-375G>C upstream_gene_variant 0.68
rpoB 763005 p.Cys1067Val missense_variant 0.69
rpoC 763013 c.-357C>A upstream_gene_variant 0.7
rpoC 763022 c.-348C>A upstream_gene_variant 0.76
rpoC 763028 c.-342T>C upstream_gene_variant 0.76
rpoC 763053 c.-317T>C upstream_gene_variant 0.82
rpoB 763074 p.Thr1090Val missense_variant 0.6
rpoC 763088 c.-282C>G upstream_gene_variant 0.43
rpoC 763094 c.-276G>C upstream_gene_variant 0.33
rpoC 763570 c.201G>C synonymous_variant 0.6
rpoC 763573 c.204G>C synonymous_variant 0.6
rpoC 763578 p.Phe70Tyr missense_variant 0.6
rpoC 763594 c.225C>T synonymous_variant 0.8
rpoC 763603 c.234C>T synonymous_variant 0.77
rpoC 763609 c.240C>T synonymous_variant 0.77
rpoC 763619 p.Arg84Lys missense_variant 0.77
rpoC 763622 p.Ala85Ser missense_variant 0.77
rpoC 763630 c.261G>T synonymous_variant 0.76
rpoC 763633 c.264T>C synonymous_variant 0.72
rpoC 763642 c.273G>C synonymous_variant 0.81
rpoC 763654 c.285C>T synonymous_variant 0.83
rpoC 763660 c.291T>G synonymous_variant 0.84
rpoC 763666 c.297G>T synonymous_variant 0.84
rpoC 763669 c.300C>G synonymous_variant 0.81
rpoC 763672 c.303C>A synonymous_variant 0.81
rpoC 763696 c.327T>C synonymous_variant 0.74
rpoC 763699 c.330G>T synonymous_variant 0.74
rpoC 763702 c.333C>T synonymous_variant 0.74
rpoC 763705 c.336G>C synonymous_variant 0.74
rpoC 763708 c.339G>C synonymous_variant 0.74
rpoC 763714 c.345G>C synonymous_variant 0.74
rpoC 763717 c.348T>C synonymous_variant 0.74
rpoC 763732 c.363C>T synonymous_variant 0.73
rpoC 763741 c.372C>T synonymous_variant 0.62
rpoC 763744 c.375G>C synonymous_variant 0.4
rpoC 764311 c.942C>G synonymous_variant 0.81
rpoC 764314 c.945C>T synonymous_variant 0.81
rpoC 764318 p.Val317Ile missense_variant 0.84
rpoC 764326 c.957G>T synonymous_variant 0.85
rpoC 764329 c.960C>T synonymous_variant 0.85
rpoC 764335 c.966G>A synonymous_variant 0.84
rpoC 764359 c.990C>G synonymous_variant 0.84
rpoC 764365 c.996C>T synonymous_variant 0.84
rpoC 764371 c.1002G>C synonymous_variant 0.83
rpoC 764374 c.1005C>T synonymous_variant 0.83
rpoC 764377 c.1008C>T synonymous_variant 0.83
rpoC 764380 c.1011G>C synonymous_variant 0.83
rpoC 764387 c.1018T>C synonymous_variant 0.83
rpoC 764398 c.1029G>C synonymous_variant 0.77
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.7
rpoC 764410 c.1041G>T synonymous_variant 0.64
rpoC 764422 c.1053C>T synonymous_variant 0.5
rpoC 764455 c.1086G>T synonymous_variant 0.33
rpoC 764458 c.1089G>A synonymous_variant 0.33
rpoC 764461 c.1092A>G synonymous_variant 0.33
rpoC 764470 c.1101C>G synonymous_variant 0.33
rpoC 764473 c.1104C>T synonymous_variant 0.33
rpoC 764485 c.1116G>C synonymous_variant 0.33
rpoC 764512 c.1143G>C synonymous_variant 0.62
rpoC 764518 c.1149C>T synonymous_variant 0.62
rpoC 764521 c.1152T>C synonymous_variant 0.62
rpoC 764530 c.1161C>T synonymous_variant 0.73
rpoC 764536 c.1167G>T synonymous_variant 0.7
rpoC 764539 c.1170C>G synonymous_variant 0.7
rpoC 764542 c.1173C>T synonymous_variant 0.75
rpoC 764548 c.1179G>T synonymous_variant 0.89
rpoC 764566 c.1197C>G synonymous_variant 0.94
rpoC 764572 c.1203G>C synonymous_variant 0.94
rpoC 764575 c.1206T>G synonymous_variant 0.91
rpoC 764578 c.1209C>T synonymous_variant 0.91
rpoC 764581 c.1212T>C synonymous_variant 0.91
rpoC 764582 c.1213C>T synonymous_variant 0.91
rpoC 764605 c.1236G>C synonymous_variant 0.94
rpoC 764611 c.1242G>C synonymous_variant 0.93
rpoC 764623 c.1254C>G synonymous_variant 0.85
rpoC 764626 c.1257C>T synonymous_variant 0.85
rpoC 764632 c.1263T>C synonymous_variant 0.85
rpoC 764635 c.1266C>G synonymous_variant 0.85
rpoC 764644 c.1275G>T synonymous_variant 0.73
rpoC 764854 c.1485G>A synonymous_variant 0.4
rpoC 764858 p.Leu497Met missense_variant 0.6
rpoC 764863 c.1494G>C synonymous_variant 0.71
rpoC 764869 c.1500C>T synonymous_variant 0.83
rpoC 764875 c.1506C>T synonymous_variant 0.85
rpoC 764878 c.1509C>G synonymous_variant 0.85
rpoC 764887 c.1518G>C synonymous_variant 0.83
rpoC 764888 c.1519T>C synonymous_variant 0.83
rpoC 764911 c.1542A>G synonymous_variant 0.92
rpoC 764913 p.Met515Lys missense_variant 0.92
rpoC 764920 c.1551G>T synonymous_variant 0.95
rpoC 764923 c.1554A>G synonymous_variant 0.95
rpoC 764926 c.1557C>T synonymous_variant 0.95
rpoC 764932 c.1563C>T synonymous_variant 0.95
rpoC 764948 c.1579T>C synonymous_variant 0.94
rpoC 764952 p.Val528Ala missense_variant 0.94
rpoC 764968 c.1599T>C synonymous_variant 0.82
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 778782 p.Lys42Glu missense_variant 0.67
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781763 c.204C>G synonymous_variant 0.21
rpsL 781766 c.207C>T synonymous_variant 0.21
rpsL 781793 c.234G>C synonymous_variant 0.5
rpsL 781799 c.240G>C synonymous_variant 0.5
rpsL 781802 c.243G>C synonymous_variant 0.5
rpsL 781805 c.246G>C synonymous_variant 0.5
rpsL 781817 c.258G>T synonymous_variant 0.5
rpsL 781829 c.270G>T synonymous_variant 0.5
rpsL 781838 c.279G>T synonymous_variant 0.5
rpsL 781841 c.282C>T synonymous_variant 0.5
rplC 800654 c.-155T>C upstream_gene_variant 0.4
rplC 800669 c.-140G>T upstream_gene_variant 0.55
rplC 800672 c.-137G>C upstream_gene_variant 0.58
rplC 800693 c.-116A>T upstream_gene_variant 0.59
rplC 800702 c.-107G>C upstream_gene_variant 0.56
rplC 800703 c.-106T>C upstream_gene_variant 0.56
rplC 800714 c.-95C>T upstream_gene_variant 0.53
rplC 800715 c.-94A>C upstream_gene_variant 0.53
rplC 800720 c.-89T>C upstream_gene_variant 0.53
rplC 800723 c.-86C>A upstream_gene_variant 0.53
rplC 800726 c.-83G>C upstream_gene_variant 0.53
rplC 800741 c.-68C>T upstream_gene_variant 0.62
rplC 800744 c.-65G>T upstream_gene_variant 0.56
rplC 800747 c.-62C>T upstream_gene_variant 0.56
rplC 800759 c.-50C>T upstream_gene_variant 0.42
rplC 800768 c.-41C>A upstream_gene_variant 0.4
rplC 800780 c.-29C>G upstream_gene_variant 0.29
fbiC 1303095 c.165G>A synonymous_variant 1.0
fbiC 1305196 p.Ala756Thr missense_variant 0.18
embR 1417464 c.-117C>T upstream_gene_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.96
rrs 1471922 n.78T>C non_coding_transcript_exon_variant 0.89
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.96
rrs 1471925 n.80_81insTG non_coding_transcript_exon_variant 0.89
rrs 1471928 n.83T>G non_coding_transcript_exon_variant 0.73
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 0.5
rrs 1472069 n.224G>A non_coding_transcript_exon_variant 0.86
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.97
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.98
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.98
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.97
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.98
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.98
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.98
rrs 1472278 n.433C>T non_coding_transcript_exon_variant 0.33
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.33
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.4
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.7
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.61
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.15
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.15
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.15
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.35
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.35
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.42
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.56
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.69
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.9
rrs 1472504 n.659A>T non_coding_transcript_exon_variant 0.91
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.91
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.94
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.96
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.95
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.95
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 0.95
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.95
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.95
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.93
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.7
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.7
rrs 1472671 n.826G>A non_coding_transcript_exon_variant 0.53
rrs 1472689 n.844C>T non_coding_transcript_exon_variant 0.25
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.9
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.9
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.86
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.76
rrs 1472840 n.995A>T non_coding_transcript_exon_variant 0.4
rrs 1472866 n.1021C>T non_coding_transcript_exon_variant 0.38
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.5
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.5
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.55
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.56
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.93
rrs 1472974 n.1129A>T non_coding_transcript_exon_variant 0.92
rrs 1472977 n.1133dupT non_coding_transcript_exon_variant 0.93
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.95
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.9
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.75
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.18
rrs 1473132 n.1287T>C non_coding_transcript_exon_variant 0.73
rrs 1473135 n.1290C>T non_coding_transcript_exon_variant 0.83
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.88
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.91
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.95
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.97
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.96
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.95
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 0.92
rrs 1473293 n.1448G>T non_coding_transcript_exon_variant 0.92
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.92
rrs 1473346 n.1501G>C non_coding_transcript_exon_variant 0.8
rrs 1473365 n.1520C>G non_coding_transcript_exon_variant 0.4
rrl 1473390 n.-268A>T upstream_gene_variant 0.22
rrl 1473447 n.-211G>T upstream_gene_variant 0.2
rrl 1473697 n.40C>G non_coding_transcript_exon_variant 0.83
rrl 1473698 n.41G>C non_coding_transcript_exon_variant 0.83
rrl 1473699 n.42A>T non_coding_transcript_exon_variant 0.83
rrl 1473718 n.61G>A non_coding_transcript_exon_variant 0.81
rrl 1473719 n.62G>A non_coding_transcript_exon_variant 0.81
rrl 1473728 n.71A>T non_coding_transcript_exon_variant 0.81
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.81
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.8
rrl 1473750 n.93C>T non_coding_transcript_exon_variant 0.8
rrl 1473751 n.94C>T non_coding_transcript_exon_variant 0.8
rrl 1473752 n.95G>A non_coding_transcript_exon_variant 0.6
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.83
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.85
rrl 1473884 n.227C>T non_coding_transcript_exon_variant 0.57
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.57
rrl 1473889 n.232G>A non_coding_transcript_exon_variant 0.57
rrl 1473896 n.239C>T non_coding_transcript_exon_variant 0.57
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.6
rrl 1473911 n.254G>A non_coding_transcript_exon_variant 0.62
rrl 1473918 n.261C>T non_coding_transcript_exon_variant 0.62
rrl 1473922 n.265A>T non_coding_transcript_exon_variant 0.59
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.59
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.61
rrl 1473936 n.279A>G non_coding_transcript_exon_variant 0.61
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.61
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.56
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.58
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.58
rrl 1473950 n.293G>T non_coding_transcript_exon_variant 0.58
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 0.6
rrl 1474112 n.455T>G non_coding_transcript_exon_variant 0.29
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.78
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.84
rrl 1474142 n.485C>T non_coding_transcript_exon_variant 0.86
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.86
rrl 1474182 n.525C>A non_coding_transcript_exon_variant 0.91
rrl 1474183 n.526T>G non_coding_transcript_exon_variant 0.91
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.91
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.91
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.94
rrl 1474199 n.542G>T non_coding_transcript_exon_variant 0.94
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.95
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.92
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.91
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.86
rrl 1474293 n.637_651delCCTCTCCGGAGGAGG non_coding_transcript_exon_variant 0.74
rrl 1474311 n.654_655insT non_coding_transcript_exon_variant 0.7
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.15
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.15
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.15
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.35
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.56
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.6
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.58
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.58
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.58
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.58
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.6
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.62
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.65
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.64
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.76
rrl 1474527 n.870T>G non_coding_transcript_exon_variant 0.84
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.91
rrl 1474542 n.885A>C non_coding_transcript_exon_variant 0.89
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.81
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.81
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.76
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.72
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.72
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.87
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.95
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.97
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.98
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.98
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.99
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.99
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.99
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.99
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.98
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.99
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.98
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.96
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.95
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.94
rrl 1474917 n.1260G>T non_coding_transcript_exon_variant 0.94
rrl 1474918 n.1261T>C non_coding_transcript_exon_variant 0.65
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 0.94
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.89
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.4
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.94
rrl 1475514 n.1857G>A non_coding_transcript_exon_variant 0.91
rrl 1475522 n.1865A>T non_coding_transcript_exon_variant 0.91
rrl 1475525 n.1868G>A non_coding_transcript_exon_variant 0.91
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.91
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.95
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.95
rrl 1475542 n.1885A>G non_coding_transcript_exon_variant 0.95
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.95
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.95
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.95
rrl 1475562 n.1905C>T non_coding_transcript_exon_variant 0.96
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.8
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.5
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.5
rrl 1475688 n.2031G>A non_coding_transcript_exon_variant 0.4
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.4
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.4
rrl 1475704 n.2047C>T non_coding_transcript_exon_variant 0.4
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.82
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.9
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.89
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.96
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.97
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.98
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.98
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.98
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.98
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.98
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.98
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.98
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.97
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.97
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.95
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.51
rrl 1476033 n.2376T>A non_coding_transcript_exon_variant 0.95
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.94
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 1.0
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 1.0
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.97
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.97
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.98
rrl 1476080 n.2423T>G non_coding_transcript_exon_variant 0.98
rrl 1476085 n.2428G>A non_coding_transcript_exon_variant 0.97
rrl 1476097 n.2440C>T non_coding_transcript_exon_variant 0.96
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.96
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 0.96
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.93
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.93
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.93
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.95
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.96
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.98
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.98
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.98
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.98
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.97
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.97
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.97
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 0.97
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.97
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.97
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.97
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.98
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.99
rrl 1476298 n.2641C>A non_coding_transcript_exon_variant 0.99
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.99
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.99
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.99
rrl 1476309 n.2652G>T non_coding_transcript_exon_variant 0.99
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.99
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476535 n.2878G>A non_coding_transcript_exon_variant 0.98
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.98
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.97
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.97
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.96
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.96
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.97
rrl 1476605 n.2948C>T non_coding_transcript_exon_variant 0.94
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.96
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.95
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.95
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.93
rrl 1476624 n.2967T>A non_coding_transcript_exon_variant 0.93
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.93
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.93
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.93
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.5
inhA 1674535 p.Pro112Thr missense_variant 0.18
rpsA 1833649 c.108C>T synonymous_variant 1.0
rpsA 1833655 c.114C>T synonymous_variant 1.0
rpsA 1833661 c.120A>G synonymous_variant 1.0
rpsA 1833664 c.123C>T synonymous_variant 0.67
rpsA 1833667 c.126C>T synonymous_variant 0.67
rpsA 1833668 p.Ile43Val missense_variant 0.67
rpsA 1833676 c.135A>G synonymous_variant 0.5
rpsA 1833679 c.138G>T synonymous_variant 0.5
rpsA 1833684 p.Arg48His missense_variant 0.5
rpsA 1833694 c.153G>A synonymous_variant 0.4
rpsA 1833697 c.156C>G synonymous_variant 0.4
rpsA 1833700 c.159C>G synonymous_variant 0.4
rpsA 1833709 c.168C>A synonymous_variant 0.4
rpsA 1833724 c.183C>T synonymous_variant 0.4
rpsA 1834009 c.468C>T synonymous_variant 0.18
rpsA 1834012 c.471G>C synonymous_variant 0.18
rpsA 1834015 c.474G>C synonymous_variant 0.2
rpsA 1834018 c.477C>T synonymous_variant 0.22
rpsA 1834025 p.Gln162Glu missense_variant 0.2
rpsA 1834030 c.489C>G synonymous_variant 0.2
rpsA 1834040 p.Lys167Gln missense_variant 0.27
rpsA 1834046 p.Ile169Leu missense_variant 0.38
rpsA 1834051 c.510G>A synonymous_variant 0.38
rpsA 1834054 c.513C>T synonymous_variant 0.5
rpsA 1834076 p.Asn179Gln missense_variant 0.55
rpsA 1834090 c.549G>T synonymous_variant 0.6
rpsA 1834093 c.552G>C synonymous_variant 0.6
rpsA 1834096 c.555G>C synonymous_variant 0.67
rpsA 1834102 c.561T>C synonymous_variant 0.67
rpsA 1834105 c.564C>T synonymous_variant 0.67
rpsA 1834108 c.567C>A synonymous_variant 0.67
rpsA 1834110 p.Trp190Tyr missense_variant 0.57
rpsA 1834114 c.573G>C synonymous_variant 0.57
rpsA 1834135 c.594G>T synonymous_variant 0.5
rpsA 1834139 c.598_599delAGinsTC synonymous_variant 0.5
rpsA 1834183 c.642T>C synonymous_variant 0.33
rpsA 1834186 c.645C>T synonymous_variant 0.43
rpsA 1834189 c.648G>T synonymous_variant 0.5
rpsA 1834195 c.654G>C synonymous_variant 0.73
rpsA 1834213 c.672G>C synonymous_variant 0.9
rpsA 1834234 c.693G>C synonymous_variant 0.86
rpsA 1834240 c.699T>C synonymous_variant 0.83
rpsA 1834246 c.705G>T synonymous_variant 0.86
rpsA 1834249 c.708T>C synonymous_variant 0.86
rpsA 1834252 c.711C>T synonymous_variant 0.86
rpsA 1834261 c.720A>G synonymous_variant 0.86
rpsA 1834264 c.723G>T synonymous_variant 0.83
rpsA 1834276 c.735C>T synonymous_variant 0.78
rpsA 1834285 c.744G>A synonymous_variant 0.75
rpsA 1834288 c.747C>T synonymous_variant 0.75
rpsA 1834294 c.753G>T synonymous_variant 0.62
rpsA 1834298 p.Gln253Thr missense_variant 0.45
rpsA 1834654 c.1113G>A synonymous_variant 0.5
rpsA 1834663 c.1122C>T synonymous_variant 0.4
rpsA 1834667 p.Ala376Ser missense_variant 0.4
rpsA 1834684 c.1143C>T synonymous_variant 0.43
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.43
rpsA 1834712 p.Ile391Val missense_variant 0.38
rpsA 1834720 c.1179C>T synonymous_variant 0.38
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2156196 c.-85C>T upstream_gene_variant 1.0
PPE35 2167995 p.Ser873Ile missense_variant 1.0
Rv1979c 2222289 c.876C>G synonymous_variant 0.22
Rv1979c 2222883 c.282C>T synonymous_variant 0.29
Rv1979c 2223077 p.Ala30Thr missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2725978 c.-215G>T upstream_gene_variant 0.5
ahpC 2726022 c.-171C>A upstream_gene_variant 0.25
folC 2746340 p.Ala420Val missense_variant 1.0
ribD 2987413 p.Thr192Ile missense_variant 0.29
thyA 3073868 p.Thr202Ala missense_variant 1.0
Rv3083 3449213 p.Arg237Leu missense_variant 0.29
fprA 3473888 c.-119G>T upstream_gene_variant 0.2
fprA 3474952 p.Gln316Lys missense_variant 0.4
fprA 3475053 c.1049delG frameshift_variant 0.4
fbiB 3641782 p.Val83Ala missense_variant 0.29
alr 3840582 p.Ala280Asp missense_variant 0.29
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4038539 c.2166G>C synonymous_variant 0.33
clpC1 4038556 p.Ile717Val missense_variant 0.38
clpC1 4038563 c.2142C>T synonymous_variant 0.33
clpC1 4038569 c.2136C>T synonymous_variant 0.33
clpC1 4038575 c.2128_2130delCTCinsTTG synonymous_variant 0.38
clpC1 4038584 c.2121G>A synonymous_variant 0.5
clpC1 4038596 c.2109A>G synonymous_variant 0.43
clpC1 4038623 c.2082A>G synonymous_variant 0.43
clpC1 4038632 p.Glu691Asp missense_variant 0.29
clpC1 4038968 c.1737G>A synonymous_variant 1.0
clpC1 4039817 c.888A>T synonymous_variant 0.38
clpC1 4039826 c.879C>T synonymous_variant 0.5
clpC1 4039831 c.874T>C synonymous_variant 0.55
clpC1 4039838 p.Leu289Ile missense_variant 0.6
clpC1 4039844 c.861C>T synonymous_variant 0.55
clpC1 4039850 c.855T>C synonymous_variant 0.55
clpC1 4039855 c.850C>T synonymous_variant 0.5
clpC1 4039865 c.840T>C synonymous_variant 0.46
clpC1 4039871 p.Thr278Gln missense_variant 0.46
clpC1 4039877 c.828C>T synonymous_variant 0.43
clpC1 4039898 c.807C>G synonymous_variant 0.43
clpC1 4039910 c.795C>T synonymous_variant 0.5
clpC1 4040508 p.Ile66Asn missense_variant 0.33
clpC1 4040763 c.-59C>A upstream_gene_variant 0.5
embC 4240055 p.Gly65Ser missense_variant 0.5
embC 4240435 c.573C>T synonymous_variant 0.4
embC 4241891 p.Ala677Pro missense_variant 0.4
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243180 c.-53C>A upstream_gene_variant 0.25
embA 4243513 p.Pro94Leu missense_variant 0.17
embA 4244440 p.Gly403Glu missense_variant 0.29
embA 4246297 p.Gln1022Arg missense_variant 0.25
ethA 4326252 p.Tyr408Asp missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0