TB-Profiler result

Run: SRR1175474
Summary

Run ID: SRR1175474

Sample name:

Date: 03-04-2023 03:39:46

Number of reads: 97746

Percentage reads mapped: 7.06

Strain: lineage4.9

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
lineage4.3.4.1 Euro-American (LAM) LAM1;LAM2 RD174 0.07
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.96 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.94 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
pncA 2289050 c.182_191delCACCGGACTA frameshift_variant 1.0 pyrazinamide, pyrazinamide
embB 4247431 p.Met306Ile missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5937 p.Ala233Glu missense_variant 0.5
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7391 c.90C>T synonymous_variant 0.5
gyrA 7394 c.93T>C synonymous_variant 0.5
gyrA 7397 c.96G>C synonymous_variant 0.5
gyrA 7403 c.102C>T synonymous_variant 0.5
gyrA 7412 c.111C>G synonymous_variant 0.5
gyrA 7421 c.120G>C synonymous_variant 0.5
gyrA 7424 c.123G>C synonymous_variant 0.5
gyrA 7427 c.126G>C synonymous_variant 0.5
gyrA 7433 c.132G>C synonymous_variant 0.5
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491366 p.Thr195Lys missense_variant 0.4
rpoB 760101 c.295T>C synonymous_variant 0.67
rpoB 760110 c.304_306delTCTinsAGC synonymous_variant 0.67
rpoB 760118 c.312T>G synonymous_variant 0.67
rpoB 760121 c.315T>C synonymous_variant 0.67
rpoB 760130 p.Asp108Glu missense_variant 0.67
rpoB 760139 c.333A>G synonymous_variant 0.67
rpoB 760184 c.378A>G synonymous_variant 0.4
rpoB 760235 c.429T>C synonymous_variant 0.5
rpoB 760244 c.438G>C synonymous_variant 0.5
rpoB 760991 c.1185G>C synonymous_variant 0.5
rpoB 760997 c.1191G>C synonymous_variant 0.43
rpoB 761003 c.1197C>G synonymous_variant 0.38
rpoB 761006 c.1200C>G synonymous_variant 0.5
rpoB 761013 p.Val403Ile missense_variant 0.43
rpoB 761027 c.1221A>G synonymous_variant 0.5
rpoB 761036 c.1230G>C synonymous_variant 0.57
rpoB 761037 c.1231T>C synonymous_variant 0.67
rpoB 761046 p.Ile414Val missense_variant 0.5
rpoB 761051 c.1245G>C synonymous_variant 0.6
rpoB 761054 c.1248G>T synonymous_variant 0.6
rpoB 761057 c.1251G>C synonymous_variant 0.5
rpoB 761147 c.1341C>T synonymous_variant 1.0
rpoB 761150 c.1344A>C synonymous_variant 1.0
rpoB 761153 c.1347G>C synonymous_variant 1.0
rpoB 761159 c.1353G>C synonymous_variant 1.0
rpoB 761162 c.1356G>C synonymous_variant 1.0
rpoB 761165 c.1359G>C synonymous_variant 1.0
rpoB 761171 c.1365C>T synonymous_variant 1.0
rpoB 761180 c.1374A>G synonymous_variant 1.0
rpoB 761189 c.1383T>C synonymous_variant 1.0
rpoB 761192 c.1386C>G synonymous_variant 0.67
rpoB 761195 c.1389G>C synonymous_variant 1.0
rpoB 761196 p.Leu464Val missense_variant 0.67
rpoB 761207 c.1401C>T synonymous_variant 0.67
rpoB 761213 c.1407G>C synonymous_variant 0.67
rpoB 761234 c.1428G>C synonymous_variant 1.0
rpoB 761537 c.1731C>G synonymous_variant 0.88
rpoB 761557 p.Ala584Gly missense_variant 0.78
rpoB 761562 p.Ala586Ser missense_variant 0.88
rpoB 761565 p.Met587Leu missense_variant 0.88
rpoB 761570 c.1764T>C synonymous_variant 0.88
rpoB 761573 c.1767C>G synonymous_variant 0.88
rpoB 761579 c.1773G>C synonymous_variant 0.88
rpoB 761594 c.1788C>G synonymous_variant 0.88
rpoB 761600 c.1794T>C synonymous_variant 0.88
rpoB 761612 c.1806G>T synonymous_variant 0.83
rpoB 761615 c.1809A>C synonymous_variant 0.71
rpoB 762167 c.2361T>C synonymous_variant 1.0
rpoB 762176 c.2370T>C synonymous_variant 1.0
rpoB 762180 p.Asp792Pro missense_variant 1.0
rpoB 762185 c.2379G>C synonymous_variant 1.0
rpoB 762194 c.2388G>C synonymous_variant 1.0
rpoB 762209 c.2403C>G synonymous_variant 1.0
rpoB 762212 c.2406G>C synonymous_variant 1.0
rpoB 762218 c.2412T>C synonymous_variant 1.0
rpoB 762231 c.2425_2426insG frameshift_variant 1.0
rpoB 762235 c.2431delG frameshift_variant 1.0
rpoB 762245 c.2439G>C synonymous_variant 1.0
rpoB 762254 c.2448T>C synonymous_variant 1.0
rpoB 762264 p.Gly820Asn missense_variant 1.0
rpoB 762273 p.Ala823Ser missense_variant 1.0
rpoB 762281 c.2475G>A synonymous_variant 1.0
rpoB 762284 c.2478G>C synonymous_variant 1.0
rpoB 762287 c.2481C>T synonymous_variant 1.0
rpoB 762293 c.2487T>C synonymous_variant 1.0
rpoB 762308 c.2502G>C synonymous_variant 1.0
rpoC 762863 c.-507T>C upstream_gene_variant 0.75
rpoB 762879 p.Met1025Leu missense_variant 0.92
rpoC 762899 c.-471G>C upstream_gene_variant 0.94
rpoC 762920 c.-450C>T upstream_gene_variant 0.91
rpoC 762923 c.-447C>G upstream_gene_variant 0.91
rpoC 762929 c.-441G>C upstream_gene_variant 0.91
rpoC 762959 c.-411G>C upstream_gene_variant 0.95
rpoC 762962 c.-408C>T upstream_gene_variant 0.94
rpoC 762980 c.-390T>C upstream_gene_variant 0.89
rpoC 762989 c.-381G>C upstream_gene_variant 0.83
rpoC 762995 c.-375G>C upstream_gene_variant 0.8
rpoB 763005 p.Cys1067Gly missense_variant 0.67
rpoC 763070 c.-300T>C upstream_gene_variant 0.56
rpoB 763075 p.Thr1090Ile missense_variant 0.6
rpoC 763082 c.-288C>A upstream_gene_variant 0.67
rpoC 763094 c.-276G>C upstream_gene_variant 0.62
rpoB 763126 p.Pro1107Gln missense_variant 0.73
rpoC 763133 c.-237G>C upstream_gene_variant 0.73
rpoC 763148 c.-222G>C upstream_gene_variant 0.62
rpoC 763160 c.-210G>C upstream_gene_variant 0.71
rpoB 763161 p.Leu1119Met missense_variant 0.6
rpoC 763166 c.-204A>G upstream_gene_variant 0.6
rpoC 763169 c.-201A>G upstream_gene_variant 0.6
rpoB 763170 p.Leu1122Met missense_variant 0.6
rpoC 763181 c.-189G>C upstream_gene_variant 0.6
rpoC 763187 c.-183C>G upstream_gene_variant 0.6
rpoC 763483 c.114G>C synonymous_variant 0.8
rpoC 763486 c.117T>C synonymous_variant 0.75
rpoC 763492 c.123G>C synonymous_variant 0.71
rpoC 763504 c.135C>T synonymous_variant 0.75
rpoC 763511 p.Cys48Gly missense_variant 0.82
rpoC 763517 p.Lys50Gln missense_variant 0.85
rpoC 763528 c.159G>T synonymous_variant 0.85
rpoC 763532 p.Thr55Ser missense_variant 0.85
rpoC 763546 c.177A>G synonymous_variant 0.92
rpoC 763550 p.Tyr61Ala missense_variant 0.92
rpoC 763570 c.201G>T synonymous_variant 0.82
rpoC 763573 c.204G>C synonymous_variant 0.83
rpoC 763589 p.Ile74Val missense_variant 0.86
rpoC 763615 c.246G>C synonymous_variant 0.86
rpoC 763619 p.Arg84Lys missense_variant 0.83
rpoC 763622 p.Ala85Ser missense_variant 0.83
rpoC 763625 p.Lys86Ser missense_variant 0.83
rpoC 763636 c.267T>C synonymous_variant 0.81
rpoC 763642 c.273G>C synonymous_variant 0.84
rpoC 763657 c.288G>A synonymous_variant 0.9
rpoC 763660 c.291T>C synonymous_variant 0.9
rpoC 763666 c.297G>C synonymous_variant 0.92
rpoC 763696 c.327T>C synonymous_variant 0.95
rpoC 763708 c.339G>C synonymous_variant 0.95
rpoC 763711 c.342G>C synonymous_variant 0.95
rpoC 763717 c.348T>C synonymous_variant 0.95
rpoC 763723 c.354G>C synonymous_variant 0.95
rpoC 763727 p.Leu120Met missense_variant 0.94
rpoC 763732 c.363C>G synonymous_variant 0.94
rpoC 763744 c.375G>C synonymous_variant 0.92
rpoC 763751 p.Ile128Val missense_variant 0.9
rpoC 763765 c.396T>C synonymous_variant 0.8
rpoC 763772 p.Val135Met missense_variant 0.67
rpoC 764365 c.996C>T synonymous_variant 0.69
rpoC 764371 c.1002G>C synonymous_variant 0.73
rpoC 764377 c.1008C>G synonymous_variant 0.73
rpoC 764380 c.1011G>C synonymous_variant 0.73
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.6
rpoC 764387 c.1018T>C synonymous_variant 0.73
rpoC 764398 c.1029G>A synonymous_variant 0.59
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.67
rpoC 764410 c.1041G>C synonymous_variant 0.6
rpoC 764431 c.1062G>C synonymous_variant 0.33
rpoC 764435 c.1066A>C synonymous_variant 0.29
rpoC 764446 c.1077T>C synonymous_variant 0.25
rpoC 764449 c.1080G>C synonymous_variant 0.25
rpoC 764455 c.1086G>C synonymous_variant 0.4
rpoC 764458 c.1089G>C synonymous_variant 0.56
rpoC 764461 c.1092A>G synonymous_variant 0.44
rpoC 764497 c.1128A>G synonymous_variant 0.56
rpoC 764498 p.Ser377Ala missense_variant 0.56
rpoC 764503 c.1134G>C synonymous_variant 0.56
rpoC 764506 c.1137C>T synonymous_variant 0.56
rpoC 764521 c.1152T>C synonymous_variant 0.5
rpoC 764527 c.1158C>T synonymous_variant 0.43
rpoC 764530 c.1161C>T synonymous_variant 0.33
rpoC 764533 c.1164C>T synonymous_variant 0.33
rpoC 764536 c.1167G>T synonymous_variant 0.4
rpoC 764587 c.1218C>G synonymous_variant 0.75
rpoC 764611 c.1242G>C synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 0.91
rpoC 764635 c.1266C>G synonymous_variant 0.95
rpoC 764650 c.1281G>T synonymous_variant 0.94
rpoC 764660 p.Val431Ile missense_variant 0.94
rpoC 764677 c.1308C>G synonymous_variant 0.91
rpoC 764706 p.Leu446Gln missense_variant 0.88
rpoC 764722 c.1353G>C synonymous_variant 0.81
rpoC 764740 p.Met457Ile missense_variant 0.67
rpoC 764746 c.1377G>C synonymous_variant 0.67
rpoC 764893 c.1524T>C synonymous_variant 0.5
rpoC 764911 c.1542A>G synonymous_variant 0.67
rpoC 764912 p.Met515Gln missense_variant 0.67
rpoC 764917 c.1548G>C synonymous_variant 0.57
rpoC 764920 c.1551G>C synonymous_variant 0.57
rpoC 764923 c.1554A>G synonymous_variant 0.57
rpoC 764935 c.1566T>C synonymous_variant 0.57
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 0.5
rpoC 764953 c.1584G>C synonymous_variant 0.5
rpoC 764956 c.1587T>C synonymous_variant 0.5
rpoC 764958 p.Glu530Ala missense_variant 0.5
rpoC 764968 c.1599T>C synonymous_variant 0.5
rpoC 764995 c.1626C>G synonymous_variant 0.8
rrs 1472068 n.223T>A non_coding_transcript_exon_variant 0.67
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.91
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.96
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.92
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.92
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.92
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.94
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.96
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.93
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.91
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.89
rrs 1472256 n.411T>C non_coding_transcript_exon_variant 0.93
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.43
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.6
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.67
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.71
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.71
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.71
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.71
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.71
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.82
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.57
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.5
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.6
rrs 1472507 n.662C>T non_coding_transcript_exon_variant 0.81
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.93
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.94
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.95
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.95
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.98
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.98
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.97
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 0.97
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.97
rrs 1472660 n.815T>A non_coding_transcript_exon_variant 0.97
rrs 1472666 n.821G>T non_coding_transcript_exon_variant 0.95
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.93
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.93
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.93
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.87
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.87
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.81
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.87
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.85
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.86
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.91
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.85
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.79
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.98
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.94
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.98
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.98
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.97
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.96
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.96
rrs 1472991 n.1146G>A non_coding_transcript_exon_variant 0.96
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.96
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.96
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.89
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.89
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.9
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.88
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.86
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.88
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.85
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.86
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.87
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.9
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.88
rrs 1473134 n.1289T>C non_coding_transcript_exon_variant 0.9
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.91
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.93
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.95
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.96
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.97
rrs 1473269 n.1424C>T non_coding_transcript_exon_variant 0.97
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.98
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.98
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.98
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.95
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.93
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.91
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.91
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.91
rrl 1473813 n.157_158delAT non_coding_transcript_exon_variant 0.5
rrl 1473828 n.173_174delTG non_coding_transcript_exon_variant 0.6
rrl 1473834 n.178_179insTAG non_coding_transcript_exon_variant 0.6
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.8
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.82
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.82
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.82
rrl 1473883 n.226A>G non_coding_transcript_exon_variant 0.82
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.82
rrl 1473888 n.231T>C non_coding_transcript_exon_variant 0.82
rrl 1473890 n.233T>C non_coding_transcript_exon_variant 0.82
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.9
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.9
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0
rrl 1473917 n.260G>C non_coding_transcript_exon_variant 1.0
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 1.0
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.67
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.83
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 1.0
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 1.0
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.96
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.88
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.96
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.88
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.76
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.8
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.67
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.33
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.33
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.8
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.86
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.93
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.93
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.96
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.89
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.89
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.87
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.87
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.9
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.93
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.9
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.91
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.96
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.97
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.94
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.94
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.94
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.94
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.9
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.6
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.67
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.9
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.9
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.9
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.94
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.88
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.88
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 1.0
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.89
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 1.0
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.95
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.98
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.94
rrl 1474830 n.1173A>C non_coding_transcript_exon_variant 0.98
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.93
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.93
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.96
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.91
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.95
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.89
rrl 1474935 n.1278A>G non_coding_transcript_exon_variant 0.86
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 1.0
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 0.33
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 0.33
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.5
rrl 1475078 n.1421T>A non_coding_transcript_exon_variant 0.38
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.6
rrl 1475084 n.1427G>T non_coding_transcript_exon_variant 0.64
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.73
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.73
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 0.73
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.82
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.82
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 0.73
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.73
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.73
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.73
rrl 1475488 n.1831G>C non_coding_transcript_exon_variant 0.4
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.88
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.94
rrl 1475536 n.1879C>A non_coding_transcript_exon_variant 0.88
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.94
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.94
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.83
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.83
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.83
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.79
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.5
rrl 1475652 n.1995C>T non_coding_transcript_exon_variant 0.67
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.8
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.8
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.89
rrl 1475692 n.2035G>C non_coding_transcript_exon_variant 0.95
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.96
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.97
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.91
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.92
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.91
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.91
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.9
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.9
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.9
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.89
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.89
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.89
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.85
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.81
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.85
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.75
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.69
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.7
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.7
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.7
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.7
rrl 1476046 n.2389G>C non_coding_transcript_exon_variant 0.7
rrl 1476047 n.2390G>C non_coding_transcript_exon_variant 0.7
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.7
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.73
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.7
rrl 1476079 n.2422G>A non_coding_transcript_exon_variant 0.4
rrl 1476080 n.2423T>C non_coding_transcript_exon_variant 0.5
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.4
rrl 1476082 n.2425T>C non_coding_transcript_exon_variant 0.4
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.6
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.4
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.44
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.5
rrl 1476104 n.2448delG non_coding_transcript_exon_variant 0.5
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.62
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.64
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.9
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.91
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.9
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.95
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.95
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.94
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.93
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.93
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.95
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.94
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.94
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.88
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.84
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.83
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.87
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.87
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.86
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.83
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.88
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.86
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.9
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.93
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.93
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.93
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.92
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.93
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.94
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.94
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.94
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.93
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.93
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.93
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.93
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.93
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.94
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.95
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.95
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.96
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.93
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.88
rrl 1476601 n.2944G>A non_coding_transcript_exon_variant 0.88
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.92
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.85
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.89
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.88
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.82
rrl 1476630 n.2973A>T non_coding_transcript_exon_variant 0.82
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.38
rpsA 1833636 p.Tyr32Phe missense_variant 0.5
rpsA 1833646 c.105T>C synonymous_variant 0.67
rpsA 1833649 c.108C>A synonymous_variant 0.67
rpsA 1833653 p.Ile38Leu missense_variant 0.5
rpsA 1833656 p.Val39Ile missense_variant 0.5
rpsA 1833668 p.Ile43Val missense_variant 0.5
rpsA 1833676 c.135A>G synonymous_variant 0.5
rpsA 1833677 p.Val46Ile missense_variant 0.5
rpsA 1833685 c.144G>C synonymous_variant 0.8
rpsA 1833694 c.153G>C synonymous_variant 0.67
rpsA 1833704 p.Ile55Val missense_variant 0.67
rpsA 1833709 c.168C>T synonymous_variant 0.73
rpsA 1833721 c.180A>G synonymous_variant 0.75
rpsA 1833727 c.186G>C synonymous_variant 0.7
rpsA 1833734 p.Ala65Ser missense_variant 0.7
rpsA 1833742 c.201A>G synonymous_variant 0.7
rpsA 1833745 c.204G>T synonymous_variant 0.7
rpsA 1833748 c.207C>G synonymous_variant 0.64
rpsA 1833753 p.Lys71Arg missense_variant 0.7
rpsA 1833781 c.240T>C synonymous_variant 0.4
rpsA 1833782 p.Ser81Lys missense_variant 0.4
rpsA 1833790 c.249T>C synonymous_variant 0.67
rpsA 1833802 c.261A>G synonymous_variant 0.67
rpsA 1833811 c.270G>C synonymous_variant 0.67
rpsA 1833961 c.420C>G synonymous_variant 0.67
rpsA 1833970 c.429G>T synonymous_variant 0.67
rpsA 1833979 c.438T>C synonymous_variant 0.67
rpsA 1834030 c.489C>G synonymous_variant 1.0
rpsA 1834034 p.Ile165Leu missense_variant 0.8
rpsA 1834040 p.Lys167Gln missense_variant 0.83
rpsA 1834061 p.Ile174Leu missense_variant 1.0
rpsA 1834069 c.528G>C synonymous_variant 1.0
rpsA 1834090 c.549G>C synonymous_variant 1.0
rpsA 1834096 c.555G>C synonymous_variant 1.0
rpsA 1834099 c.558C>G synonymous_variant 1.0
rpsA 1834102 c.561T>C synonymous_variant 1.0
rpsA 1834109 p.Trp190Leu missense_variant 1.0
rpsA 1834114 c.573G>C synonymous_variant 1.0
rpsA 1834123 c.582C>G synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168850 p.Ser588* stop_gained 0.25
PPE35 2170797 c.-185A>G upstream_gene_variant 0.4
Rv1979c 2222854 p.Ile104Thr missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746481 p.Arg373Leu missense_variant 1.0
Rv2752c 3064711 p.Ser494* stop_gained 0.5
ald 3086788 c.-32T>C upstream_gene_variant 1.0
clpC1 4039898 c.807C>G synonymous_variant 0.71
clpC1 4039904 c.801A>G synonymous_variant 0.71
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.83
clpC1 4039934 c.771G>C synonymous_variant 0.83
clpC1 4039937 p.Val256Ile missense_variant 0.83
clpC1 4039946 c.759A>C synonymous_variant 0.71
clpC1 4039949 c.756G>C synonymous_variant 0.62
clpC1 4039952 c.753T>C synonymous_variant 0.62
clpC1 4039955 c.750G>C synonymous_variant 0.62
clpC1 4039960 p.Thr249Ser missense_variant 0.73
clpC1 4039966 p.Leu247Val missense_variant 0.77
clpC1 4039979 c.726C>G synonymous_variant 0.8
clpC1 4039991 c.714G>C synonymous_variant 1.0
clpC1 4039994 p.Glu237Asp missense_variant 0.78
clpC1 4039998 p.Gly236Asn missense_variant 0.78
clpC1 4040000 p.His235Lys missense_variant 0.78
clpC1 4040009 c.696C>G synonymous_variant 0.78
clpC1 4040018 c.687G>C synonymous_variant 0.78
clpC1 4040021 c.684A>C synonymous_variant 0.78
clpC1 4040024 c.681A>G synonymous_variant 0.78
clpC1 4040033 c.672G>C synonymous_variant 0.83
clpC1 4040063 c.642G>C synonymous_variant 0.88
clpC1 4040066 c.639G>C synonymous_variant 0.88
clpC1 4040069 c.636G>C synonymous_variant 0.83
clpC1 4040081 p.Thr208Ser missense_variant 0.83
clpC1 4040087 c.618G>C synonymous_variant 0.83
clpC1 4040090 c.615T>G synonymous_variant 0.83
clpC1 4040093 c.612C>G synonymous_variant 0.83
clpC1 4040096 p.Val203Ile missense_variant 0.83
clpC1 4040105 c.600C>G synonymous_variant 0.83
clpC1 4040108 c.597G>C synonymous_variant 0.83
clpC1 4040117 c.588A>G synonymous_variant 0.83
clpC1 4040129 c.576C>G synonymous_variant 0.8
clpC1 4040138 c.567G>C synonymous_variant 0.67
clpC1 4040267 c.438A>G synonymous_variant 0.5
clpC1 4040273 c.432T>C synonymous_variant 0.5
clpC1 4040276 c.429C>G synonymous_variant 0.5
clpC1 4040291 c.414G>C synonymous_variant 0.71
clpC1 4040307 p.Arg133Lys missense_variant 0.83
clpC1 4040310 p.Thr132Asn missense_variant 0.71
clpC1 4040312 c.393G>C synonymous_variant 0.83
clpC1 4040315 p.Glu130Asp missense_variant 0.71
clpC1 4040324 c.381G>C synonymous_variant 0.71
clpC1 4040333 c.372G>C synonymous_variant 0.8
clpC1 4040342 c.363C>G synonymous_variant 0.82
clpC1 4040348 c.357G>C synonymous_variant 0.82
clpC1 4040354 c.351A>G synonymous_variant 0.78
clpC1 4040357 c.348T>C synonymous_variant 0.8
clpC1 4040363 c.342A>C synonymous_variant 0.8
clpC1 4040375 c.330G>C synonymous_variant 0.71
clpC1 4040380 c.325T>C synonymous_variant 0.71
clpC1 4040381 c.324T>C synonymous_variant 0.71
clpC1 4040387 c.318A>G synonymous_variant 0.71
clpC1 4040393 c.312G>C synonymous_variant 0.62
clpC1 4040411 c.294T>G synonymous_variant 0.71
clpC1 4040432 p.Ser91Arg missense_variant 0.6
clpC1 4040695 c.10C>A synonymous_variant 0.67
embC 4241490 p.Ala543Glu missense_variant 1.0
ethA 4326447 p.Gly343Trp missense_variant 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0