TB-Profiler result

Run: ERR4872322

Summary

Run ID: ERR4872322

Sample name:

Date: 01-04-2023 21:32:37

Number of reads: 2275916

Percentage reads mapped: 58.61

Strain: lineage2.2.1

Drug-resistance: Pre-XDR-TB


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7572 p.Ser91Pro missense_variant 1.0 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
rpoB 761127 p.Ser441Ala missense_variant 0.12 rifampicin
rpoB 761155 p.Ser450Leu missense_variant 0.9 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.54 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.38 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
pncA 2288928 p.Gly105Val missense_variant 1.0 pyrazinamide
eis 2715342 c.-10G>C upstream_gene_variant 1.0 kanamycin, kanamycin
embA 4243221 c.-12C>T upstream_gene_variant 1.0 ethambutol
embB 4247399 p.Asn296His missense_variant 1.0 ethambutol
ethA 4327363 c.110delA frameshift_variant 1.0 ethionamide, ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
mshA 576113 p.Arg256Gly missense_variant 0.25
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoB 761021 c.1215G>C synonymous_variant 0.13
rpoB 761027 c.1221A>G synonymous_variant 0.16
rpoB 761036 c.1230G>C synonymous_variant 0.17
rpoB 761037 c.1231T>C synonymous_variant 0.17
rpoB 761046 p.Ile414Val missense_variant 0.15
rpoB 761051 c.1245G>C synonymous_variant 0.15
rpoB 761057 c.1251G>C synonymous_variant 0.15
rpoB 761102 c.1296A>G synonymous_variant 0.12
rpoB 761126 c.1320G>C synonymous_variant 0.12
rpoC 762959 c.-411G>C upstream_gene_variant 0.14
rpoC 762962 c.-408C>T upstream_gene_variant 0.16
rpoC 762983 c.-387C>A upstream_gene_variant 0.15
rpoC 762989 c.-381G>C upstream_gene_variant 0.14
rpoC 762995 c.-375G>T upstream_gene_variant 0.13
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763070 c.-300T>C upstream_gene_variant 0.13
rpoC 763082 c.-288C>T upstream_gene_variant 0.14
rpoC 763103 c.-267G>C upstream_gene_variant 0.14
rpoC 763507 c.138G>C synonymous_variant 0.12
rpoC 763511 p.Cys48Gly missense_variant 0.12
rpoC 763517 p.Lys50Gln missense_variant 0.12
rpoC 763528 c.159G>C synonymous_variant 0.12
rpoC 763532 p.Thr55Ser missense_variant 0.12
rpoC 763537 c.168C>T synonymous_variant 0.12
rpoC 763546 c.177A>G synonymous_variant 0.12
rpoC 763550 p.Tyr61Ala missense_variant 0.12
rpoC 763570 c.201G>C synonymous_variant 0.18
rpoC 763573 c.204G>C synonymous_variant 0.18
rpoC 763589 p.Ile74Val missense_variant 0.16
rpoC 763609 c.240C>G synonymous_variant 0.15
rpoC 763660 c.291T>C synonymous_variant 0.11
rpoC 764344 c.975C>T synonymous_variant 0.11
rpoC 764353 c.984G>C synonymous_variant 0.19
rpoC 764365 c.996C>T synonymous_variant 0.22
rpoC 764371 c.1002G>C synonymous_variant 0.16
rpoC 764377 c.1008C>G synonymous_variant 0.17
rpoC 764380 c.1011G>C synonymous_variant 0.19
rpoC 764387 c.1018T>C synonymous_variant 0.2
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.2
rpoC 764428 c.1059G>T synonymous_variant 0.19
rpoC 764431 c.1062G>C synonymous_variant 0.19
rpoC 764432 p.Lys355Arg missense_variant 0.19
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.19
rpoC 764446 c.1077T>C synonymous_variant 0.17
rpoC 764449 c.1080G>C synonymous_variant 0.17
rpoC 764455 c.1086G>C synonymous_variant 0.17
rpoC 764458 c.1089G>C synonymous_variant 0.18
rpoC 764461 c.1092A>G synonymous_variant 0.18
rpoC 764497 c.1128A>G synonymous_variant 0.13
rpoC 764498 p.Ser377Ala missense_variant 0.13
rpoC 764503 c.1134G>C synonymous_variant 0.14
rpoC 764593 c.1224C>A synonymous_variant 0.14
rpoC 764602 c.1233C>T synonymous_variant 0.15
rpoC 764605 c.1236G>C synonymous_variant 0.15
rpoC 764611 c.1242G>C synonymous_variant 0.16
rpoC 764632 c.1263T>C synonymous_variant 0.16
rpoC 764650 c.1281G>T synonymous_variant 0.15
rpoC 764662 c.1293G>C synonymous_variant 0.14
rpoC 764701 c.1332C>G synonymous_variant 0.11
rpoC 764840 p.Ile491Val missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.21
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.21
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.22
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.22
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.24
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.28
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.39
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.4
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.2
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.29
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.26
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.28
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.28
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.32
rrs 1472507 n.662C>T non_coding_transcript_exon_variant 0.41
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.55
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.56
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.56
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.6
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.59
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.59
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.57
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 0.52
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.49
rrs 1472660 n.815T>A non_coding_transcript_exon_variant 0.44
rrs 1472666 n.821G>T non_coding_transcript_exon_variant 0.43
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.4
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.38
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.38
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.37
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.38
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.37
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.38
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.39
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.4
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.38
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.25
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.21
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.42
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.42
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.43
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.43
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.47
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.46
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.47
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.47
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.51
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.48
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.48
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.52
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.52
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.52
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.51
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.5
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.5
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.5
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.51
rrs 1473134 n.1289T>C non_coding_transcript_exon_variant 0.52
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.53
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.52
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.55
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.55
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.54
rrs 1473269 n.1424C>T non_coding_transcript_exon_variant 0.5
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.49
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.46
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.46
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.38
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.38
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.38
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.12
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.13
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.13
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.13
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 0.13
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.13
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.16
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.16
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.17
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.17
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.18
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.18
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.21
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.17
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.11
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.12
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.3
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.44
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.48
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.52
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.51
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.51
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.52
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.55
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.58
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.58
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.61
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.57
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.47
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.46
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.47
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.48
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.47
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.42
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.2
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.19
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.19
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.19
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.38
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.39
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.4
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.4
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.4
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.4
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.42
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.42
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.42
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.43
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.44
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.46
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.48
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.48
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.47
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.45
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.44
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.44
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.44
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.15
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.13
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.12
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.12
rrl 1475692 n.2035G>C non_coding_transcript_exon_variant 0.36
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.6
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.62
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.7
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.67
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.67
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.67
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.67
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.69
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.67
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.66
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.64
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.62
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.59
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.57
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.51
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.5
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.51
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.31
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.28
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.26
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.26
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.26
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.28
rrl 1476046 n.2389G>C non_coding_transcript_exon_variant 0.28
rrl 1476047 n.2390G>C non_coding_transcript_exon_variant 0.27
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.28
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.3
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.29
rrl 1476079 n.2422G>A non_coding_transcript_exon_variant 0.25
rrl 1476080 n.2423T>C non_coding_transcript_exon_variant 0.24
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.24
rrl 1476082 n.2425T>C non_coding_transcript_exon_variant 0.25
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.26
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.27
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.35
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.35
rrl 1476104 n.2448delG non_coding_transcript_exon_variant 0.36
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.4
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.43
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.53
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.56
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.56
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.57
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.57
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.63
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.68
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.68
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.68
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.68
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.64
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.56
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.56
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.56
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.56
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.55
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.55
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.56
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.58
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.62
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.6
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.56
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.54
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.56
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.48
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.43
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.37
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.38
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.37
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.38
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.37
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.37
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.36
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.36
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.37
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.35
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.36
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.23
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.23
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.23
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.25
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.24
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.13
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.13
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.13
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834210 c.669C>T synonymous_variant 0.12
rpsA 1834213 c.672G>A synonymous_variant 0.12
rpsA 1834225 c.684C>G synonymous_variant 0.11
rpsA 1834231 c.690T>C synonymous_variant 0.11
rpsA 1834240 c.699T>C synonymous_variant 0.11
rpsA 1834249 c.708T>C synonymous_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.24
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.18
ald 3086731 c.-89A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.55
fbiD 3339749 p.Val211Gly missense_variant 0.23
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568428 c.252A>G synonymous_variant 0.31
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
rpoA 3878597 c.-90G>C upstream_gene_variant 0.33
rpoA 3878618 c.-111A>C upstream_gene_variant 0.67
rpoA 3878641 c.-134C>G upstream_gene_variant 0.29
clpC1 4039574 c.1131G>C synonymous_variant 0.12
clpC1 4039577 c.1128T>C synonymous_variant 0.13
clpC1 4039587 p.Ser373Gln missense_variant 0.13
clpC1 4039593 p.Arg371Gln missense_variant 0.12
clpC1 4039610 c.1095G>C synonymous_variant 0.23
clpC1 4039616 c.1089G>C synonymous_variant 0.22
clpC1 4039622 c.1083C>T synonymous_variant 0.22
clpC1 4039634 p.Glu357Asn missense_variant 0.17
clpC1 4039640 p.Thr355Ala missense_variant 0.14
clpC1 4039647 p.Glu353Pro missense_variant 0.14
clpC1 4039651 p.Val352Leu missense_variant 0.13
clpC1 4039661 p.Gly348Asn missense_variant 0.14
clpC1 4039670 c.1035G>A synonymous_variant 0.17
clpC1 4039691 c.1014G>C synonymous_variant 0.17
clpC1 4039711 p.Ile332Phe missense_variant 0.19
clpC1 4039714 p.Tyr331His missense_variant 0.18
clpC1 4039724 c.981A>G synonymous_variant 0.21
clpC1 4039742 c.963C>T synonymous_variant 0.18
clpC1 4039751 c.954A>G synonymous_variant 0.12
clpC1 4039754 c.951G>C synonymous_variant 0.11
clpC1 4039757 c.948A>G synonymous_variant 0.11
clpC1 4039766 c.939T>C synonymous_variant 0.11
clpC1 4039898 c.807C>G synonymous_variant 0.11
clpC1 4039904 c.801A>G synonymous_variant 0.14
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.14
clpC1 4039934 c.771G>C synonymous_variant 0.13
clpC1 4039937 p.Val256Ile missense_variant 0.13
clpC1 4039940 c.765G>C synonymous_variant 0.13
clpC1 4039946 c.759A>C synonymous_variant 0.12
clpC1 4039949 c.756G>C synonymous_variant 0.12
clpC1 4039952 c.753T>C synonymous_variant 0.12
clpC1 4039955 c.750G>C synonymous_variant 0.12
clpC1 4039960 p.Thr249Ser missense_variant 0.12
clpC1 4039979 c.726C>G synonymous_variant 0.14
clpC1 4039994 p.Glu237Asp missense_variant 0.12
clpC1 4040000 p.His235Lys missense_variant 0.12
clpC1 4040003 c.702G>C synonymous_variant 0.12
clpC1 4040009 c.696C>G synonymous_variant 0.12
clpC1 4040015 c.690G>C synonymous_variant 0.12
clpC1 4040018 c.687G>C synonymous_variant 0.12
clpC1 4040024 c.681A>G synonymous_variant 0.12
clpC1 4040030 c.675C>G synonymous_variant 0.12
clpC1 4040033 c.672G>C synonymous_variant 0.12
embC 4240409 p.Pro183Ala missense_variant 0.14
embC 4240413 p.Leu184Arg missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243346 c.114A>G synonymous_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.25
embB 4248324 p.Ala604Gly missense_variant 0.3
embB 4248328 c.1815G>C synonymous_variant 0.18
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338371 p.Thr51Pro missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0