TB-Profiler result

Run: 22d563d8-3c3c-42f5-aba1-36dd727b025e
Summary

Run ID: 22d563d8-3c3c-42f5-aba1-36dd727b025e

Sample name:

Date: 15-03-2024 02:52:45

Number of reads: 3900181

Percentage reads mapped: 83.13

Median coverage: 125

Strain: lineage1.2.1.2.1

Spoligotype:

Drug-resistance: MDR-TB

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1 Indo-Oceanic RD239 0.96
lineage1.2.1 Indo-Oceanic RD239 0.99
lineage1.2.1.2 Indo-Oceanic RD239 0.96
lineage1.2.1.2.1 Indo-Oceanic RD239 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser450Trp Assoc w R
isoniazid katG p.Ser315Thr Assoc w R
ethambutol
pyrazinamide
moxifloxacin
levofloxacin
bedaquiline
delamanid
pretomanid
linezolid
streptomycin gid c.351delG Assoc w R - interim
amikacin
kanamycin
capreomycin
clofazimine
ethionamide
para-aminosalicylic_acid
cycloserine
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761155 p.Ser450Trp missense_variant 0.93 rifampicin Assoc w R
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R
gid 4407851 c.351delG frameshift_variant 1.0 streptomycin Assoc w R - interim
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6112 p.Met291Ile missense_variant 0.97 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7484 c.183T>C synonymous_variant 0.1 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8452 p.Ala384Val missense_variant 0.91 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8571 c.1270C>T synonymous_variant 0.1 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.1 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.12 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9260 c.1959G>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
fgd1 491742 c.960T>C synonymous_variant 1.0 delamanid
mshA 575368 c.21T>C synonymous_variant 1.0 ethionamide
isoniazid
rpoB 760181 c.375T>C synonymous_variant 0.11 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.11 rifampicin
rpoB 760196 c.390C>G synonymous_variant 0.12 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.13 rifampicin
rpoB 760244 c.438G>C synonymous_variant 0.13 rifampicin
rpoB 760253 c.447T>C synonymous_variant 0.15 rifampicin
rpoB 760283 c.477G>C synonymous_variant 0.15 rifampicin
rpoB 760298 c.492G>C synonymous_variant 0.13 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.11 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.11 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.1 rifampicin
rpoB 760331 c.525G>T synonymous_variant 0.11 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.11 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.11 rifampicin
rpoB 760370 c.564C>G synonymous_variant 0.12 rifampicin
rpoB 760373 c.567C>G synonymous_variant 0.12 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.11 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.11 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.11 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.1 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.1 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.1 rifampicin
rpoB 761579 c.1773G>C synonymous_variant 0.1 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.11 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 0.11 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 0.11 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.11 rifampicin
rpoB 761868 p.Asp688Gln missense_variant 0.1 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.12 rifampicin
rpoB 761999 c.2193G>C synonymous_variant 0.11 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.11 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 0.11 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.14 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.15 rifampicin
rpoB 762065 c.2259T>C synonymous_variant 0.14 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.14 rifampicin
rpoB 762086 c.2280G>C synonymous_variant 0.14 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.14 rifampicin
rpoB 762114 p.Ile770Val missense_variant 0.14 rifampicin
rpoB 762122 c.2316C>T synonymous_variant 0.11 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.11 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.12 rifampicin
rpoB 762156 p.Val784Ile missense_variant 0.12 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.13 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 0.11 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.12 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.13 rifampicin
rpoB 762245 c.2439G>C synonymous_variant 0.12 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.14 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.11 rifampicin
rpoB 762293 c.2487T>G synonymous_variant 0.1 rifampicin
rpoC 763031 c.-339T>C upstream_gene_variant 1.0 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.11 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.14 rifampicin
rpoC 763166 c.-204A>G upstream_gene_variant 0.15 rifampicin
rpoC 763169 c.-201A>G upstream_gene_variant 0.13 rifampicin
rpoC 763199 c.-171G>C upstream_gene_variant 0.14 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.14 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.14 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.14 rifampicin
rpoC 763214 c.-156T>C upstream_gene_variant 0.14 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.15 rifampicin
rpoC 763232 c.-138C>G upstream_gene_variant 0.15 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.15 rifampicin
rpoC 763238 c.-132T>C upstream_gene_variant 0.15 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 0.16 rifampicin
rpoC 763259 c.-111G>T upstream_gene_variant 0.15 rifampicin
rpoC 763265 c.-105G>T upstream_gene_variant 0.15 rifampicin
rpoC 763274 c.-96G>C upstream_gene_variant 0.16 rifampicin
rpoC 763283 c.-87T>C upstream_gene_variant 0.13 rifampicin
rpoC 763289 c.-81C>G upstream_gene_variant 0.11 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.1 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.11 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.89 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.1 rifampicin
rpoC 763573 c.204G>C synonymous_variant 0.1 rifampicin
rpoC 763576 c.207C>G synonymous_variant 0.1 rifampicin
rpoC 763884 p.Ala172Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763886 c.517C>A synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.12 rifampicin
rpoC 764215 c.846A>C synonymous_variant 0.1 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.12 rifampicin
rpoC 764245 c.876C>G synonymous_variant 0.13 rifampicin
rpoC 764248 c.879C>G synonymous_variant 0.12 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.11 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.11 rifampicin
rpoC 764383 c.1014C>G synonymous_variant 0.11 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.11 rifampicin
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.11 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.12 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.14 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 0.13 rifampicin
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.13 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.14 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.15 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.15 rifampicin
rpoC 764461 c.1092A>G synonymous_variant 0.15 rifampicin
rpoC 764485 c.1116G>C synonymous_variant 0.14 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.15 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.15 rifampicin
rpoC 764500 c.1131C>G synonymous_variant 0.13 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.13 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.1 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.11 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.11 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.12 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.11 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.11 rifampicin
rpoC 764671 c.1302G>C synonymous_variant 0.14 rifampicin
rpoC 764705 c.1336C>T synonymous_variant 0.16 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.18 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.15 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.15 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.16 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.15 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 0.14 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.15 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.15 rifampicin
rpoC 764827 c.1458G>C synonymous_variant 0.15 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.11 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.11 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 0.13 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.12 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 0.14 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.14 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.15 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.15 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.15 rifampicin
rpoC 765814 c.2445A>G synonymous_variant 0.14 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.15 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 0.16 rifampicin
rpoC 765841 c.2472G>C synonymous_variant 0.17 rifampicin
rpoC 765871 c.2502T>G synonymous_variant 0.15 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.15 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.15 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.12 rifampicin
rpoC 766779 p.Glu1137Gly missense_variant 0.18 rifampicin
rpoC 767059 c.3690T>C synonymous_variant 0.1 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.14 rifampicin
rpoC 767104 c.3735C>G synonymous_variant 0.13 rifampicin
rpoC 767105 p.Asn1246Gln missense_variant 0.12 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.13 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.14 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.12 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.1 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.1 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.1 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 0.11 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.11 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 0.99 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775943 c.2538C>G synonymous_variant 0.14 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.12 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.1 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Uncertain significance
rpsL 781760 c.201T>C synonymous_variant 0.11 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.11 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.11 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.14 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.14 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.14 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.14 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.14 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.16 streptomycin
rpsL 781862 c.303G>A synonymous_variant 0.15 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.16 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.17 streptomycin
rpsL 781889 c.330C>T synonymous_variant 0.16 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.16 streptomycin
rpsL 781895 c.336G>A synonymous_variant 0.15 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.16 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.16 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.16 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.14 streptomycin Uncertain significance
fbiC 1304655 c.1725C>T synonymous_variant 0.11 delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.1 delamanid
Rv1258c 1406312 c.1029T>C synonymous_variant 1.0 streptomycin
pyrazinamide
isoniazid
embR 1417019 p.Cys110Tyr missense_variant 1.0 ethambutol Uncertain significance
atpE 1460907 c.-138T>C upstream_gene_variant 1.0 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.1 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.12 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.13 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.13 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.21 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.21 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.17 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.25 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.23 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.24 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.26 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.31 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.31 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.31 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.16 linezolid
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.16 linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473813 n.156C>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.12 linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.13 linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.11 linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.2 linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474630 n.973T>G non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474631 n.974G>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474636 n.979A>G non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.27 linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.26 linezolid
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.26 linezolid
rrl 1474718 n.1061A>T non_coding_transcript_exon_variant 0.22 linezolid
rrl 1474720 n.1065_1066delTG non_coding_transcript_exon_variant 0.22 linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.21 linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.27 linezolid
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.22 linezolid
rrl 1474965 n.1308G>T non_coding_transcript_exon_variant 0.13 linezolid
rrl 1474990 n.1333C>T non_coding_transcript_exon_variant 0.15 linezolid
rrl 1474991 n.1334T>G non_coding_transcript_exon_variant 0.15 linezolid
rrl 1474995 n.1338T>C non_coding_transcript_exon_variant 0.15 linezolid
rrl 1474997 n.1340A>G non_coding_transcript_exon_variant 0.15 linezolid
rrl 1474999 n.1342C>T non_coding_transcript_exon_variant 0.15 linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475015 n.1358C>T non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475017 n.1360_1361insA non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.22 linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.15 linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.13 linezolid
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.14 linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1475765 n.2108A>C non_coding_transcript_exon_variant 0.23 linezolid
rrl 1475766 n.2109G>C non_coding_transcript_exon_variant 0.22 linezolid
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.27 linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.24 linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.24 linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.26 linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.18 linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.19 linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.23 linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.2 linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476105 n.2448G>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.2 linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476114 n.2457T>C non_coding_transcript_exon_variant 0.21 linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.31 linezolid
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.34 linezolid
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.35 linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.39 linezolid
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.36 linezolid
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.36 linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.22 linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.22 linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.22 linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.23 linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.15 linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.13 linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476692 n.3035T>C non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.12 linezolid
inhA 1674162 c.-40C>T upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674745 p.Tyr182Val missense_variant 0.11 ethionamide
isoniazid
inhA 1674750 c.549T>G synonymous_variant 0.12 ethionamide
isoniazid
inhA 1674756 c.555T>G synonymous_variant 0.13 ethionamide
isoniazid
inhA 1674777 c.576C>A synonymous_variant 0.13 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.14 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.14 ethionamide
isoniazid
inhA 1674804 c.603G>C synonymous_variant 0.14 ethionamide
isoniazid
inhA 1674810 c.609C>G synonymous_variant 0.14 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 0.15 ethionamide
isoniazid
rpsA 1833661 c.120A>G synonymous_variant 0.13 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.15 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.15 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.15 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.15 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 0.14 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.14 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.15 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.15 pyrazinamide
rpsA 1833718 c.177C>T synonymous_variant 0.12 pyrazinamide
rpsA 1833868 c.327C>T synonymous_variant 0.1 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.1 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.12 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.12 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.13 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.13 pyrazinamide
rpsA 1833994 c.453G>A synonymous_variant 0.15 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.14 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.14 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.14 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.14 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.14 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.14 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.12 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.14 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.14 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.11 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.1 pyrazinamide
rpsA 1834183 c.642T>C synonymous_variant 0.12 pyrazinamide
rpsA 1834186 c.645C>G synonymous_variant 0.1 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.11 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.11 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.1 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.13 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.13 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.14 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.14 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.14 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.16 pyrazinamide
rpsA 1834387 c.846C>T synonymous_variant 0.14 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.13 pyrazinamide
rpsA 1834405 c.864C>T synonymous_variant 0.12 pyrazinamide
rpsA 1834408 c.867C>T synonymous_variant 0.11 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.1 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.11 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.1 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Uncertain significance
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2519048 p.Gly312Ser missense_variant 0.99 isoniazid
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0 isoniazid
thyA 3074001 c.471C>A synonymous_variant 0.1 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.11 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.11 para-aminosalicylic_acid
thyA 3074043 c.429G>A synonymous_variant 0.11 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.1 para-aminosalicylic_acid
thyA 3074055 p.Glu139Pro missense_variant 0.1 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 0.1 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
fbiD 3339417 c.300A>G synonymous_variant 1.0 delamanid
Rv3083 3448714 p.Asp71His missense_variant 1.0 ethionamide Uncertain significance
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0 capreomycin
amikacin
fprA 3474597 c.591C>A synonymous_variant 1.0 capreomycin
amikacin
fprA 3475159 p.Asn385Asp missense_variant 1.0 capreomycin Uncertain significance
amikacin Uncertain significance
whiB7 3568488 c.191delG frameshift_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
amikacin Uncertain significance
fbiB 3640557 c.-978T>C upstream_gene_variant 1.0 delamanid
rpoA 3877638 c.870T>C synonymous_variant 0.1 rifampicin
rpoA 3877647 c.861C>T synonymous_variant 0.1 rifampicin
rpoA 3877728 c.780C>G synonymous_variant 0.1 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 0.13 rifampicin
rpoA 3877857 c.651G>A synonymous_variant 0.11 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.12 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.12 rifampicin
rpoA 3877881 c.627G>C synonymous_variant 0.13 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.13 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.13 rifampicin
rpoA 3877908 c.600T>C synonymous_variant 0.12 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.12 rifampicin
rpoA 3877926 c.582G>C synonymous_variant 0.11 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.1 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.1 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.11 rifampicin
rpoA 3878169 c.339G>C synonymous_variant 0.11 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 0.13 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.12 rifampicin
rpoA 3878205 c.303T>G synonymous_variant 0.14 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.17 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.13 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.12 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.11 rifampicin
rpoA 3878283 p.Glu75Asp missense_variant 0.11 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.11 rifampicin
clpC1 4038953 c.1752A>G synonymous_variant 0.12 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.12 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.11 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.11 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.11 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.14 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.13 pyrazinamide
clpC1 4039004 c.1701C>G synonymous_variant 0.14 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.13 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 0.12 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.14 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.15 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.14 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.13 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.14 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.15 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.14 pyrazinamide
clpC1 4039145 c.1560G>T synonymous_variant 0.14 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.16 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.16 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.17 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.16 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.16 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.14 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.13 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.12 pyrazinamide
clpC1 4039226 c.1479T>A synonymous_variant 0.12 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.12 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 0.11 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.12 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.13 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.13 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.12 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.11 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.11 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.12 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.12 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.12 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.12 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.13 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.13 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.13 pyrazinamide
clpC1 4040517 p.Val63Ala missense_variant 0.99 pyrazinamide Uncertain significance
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Uncertain significance
embC 4241042 p.Asn394Asp missense_variant 0.95 ethambutol Uncertain significance
embA 4242643 c.-590C>T upstream_gene_variant 1.0 ethambutol
embA 4243580 c.348G>A synonymous_variant 1.0 ethambutol
embA 4244420 c.1188G>C synonymous_variant 0.99 ethambutol
embA 4245969 p.Pro913Ser missense_variant 1.0 ethambutol Uncertain significance
embB 4247578 c.1065G>A synonymous_variant 0.98 ethambutol
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Uncertain significance
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Uncertain significance
aftB 4269606 c.-770T>C upstream_gene_variant 1.0 capreomycin
amikacin
ubiA 4269864 c.-32delG upstream_gene_variant 1.0 ethambutol
whiB6 4338361 p.Arg54Gln missense_variant 1.0 streptomycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 streptomycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0 streptomycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin
gid 4407873 c.330G>T synonymous_variant 1.0 streptomycin