TB-Profiler result

Run: DRR185024
Summary

Run ID: DRR185024

Sample name:

Date: 31-03-2023 07:24:10

Number of reads: 606503

Percentage reads mapped: 40.38

Strain: lineage2.2.2

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.2 East-Asian (Beijing) Beijing-RD105/RD207 RD105;RD207 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.24 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.48 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.48 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.29 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575974 p.Glu209Asp missense_variant 0.17
mshA 576689 p.Tyr448Asn missense_variant 0.11
rpoB 762023 c.2217C>T synonymous_variant 0.15
rpoB 762030 p.Thr742Ser missense_variant 0.17
rpoB 762053 c.2247T>C synonymous_variant 0.19
rpoB 762056 c.2250G>A synonymous_variant 0.19
rpoB 762057 p.Ile751Val missense_variant 0.19
rpoB 762068 c.2262C>T synonymous_variant 0.19
rpoB 762080 c.2274G>C synonymous_variant 0.19
rpoB 762086 c.2280G>C synonymous_variant 0.18
rpoB 762089 c.2283G>A synonymous_variant 0.19
rpoB 762098 c.2292C>T synonymous_variant 0.19
rpoB 762101 c.2295C>G synonymous_variant 0.2
rpoB 762119 c.2313C>G synonymous_variant 0.18
rpoB 762120 p.Asp772Pro missense_variant 0.18
rpoB 762125 p.Glu773Asp missense_variant 0.18
rpoB 762127 p.Val774Ala missense_variant 0.17
rpoB 762131 c.2325C>G synonymous_variant 0.17
rpoB 762140 c.2334G>C synonymous_variant 0.17
rpoB 762143 c.2337T>C synonymous_variant 0.17
rpoB 762146 p.Glu780Asp missense_variant 0.17
rpoB 762149 c.2343G>C synonymous_variant 0.17
rpoB 762152 c.2346C>A synonymous_variant 0.17
rpoB 762156 p.Val784Ile missense_variant 0.17
rpoB 762167 c.2361T>C synonymous_variant 0.16
rpoB 762170 c.2364C>A synonymous_variant 0.16
rpoB 762176 c.2370T>C synonymous_variant 0.16
rpoB 762177 p.Arg791Thr missense_variant 0.16
rpoB 762185 c.2379G>C synonymous_variant 0.16
rpoB 762194 c.2388G>C synonymous_variant 0.16
rpoB 762233 c.2427G>T synonymous_variant 0.13
rpoB 762245 c.2439G>C synonymous_variant 0.11
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763528 c.159G>T synonymous_variant 0.12
rpoC 763558 c.189C>A synonymous_variant 0.12
rpoC 763570 c.201G>A synonymous_variant 0.13
rpoC 763597 c.228G>A synonymous_variant 0.12
rpoC 763621 c.252C>T synonymous_variant 0.12
rpoC 763636 c.267T>C synonymous_variant 0.14
rpoC 763652 p.Ile95Leu missense_variant 0.16
rpoC 763660 c.291T>C synonymous_variant 0.16
rpoC 763666 c.297G>T synonymous_variant 0.19
rpoC 763672 c.303C>G synonymous_variant 0.19
rpoC 763705 c.336G>A synonymous_variant 0.15
rpoC 763708 c.339G>T synonymous_variant 0.15
rpoC 763714 c.345G>C synonymous_variant 0.15
rpoC 763717 c.348T>C synonymous_variant 0.16
rpoC 763726 c.357C>T synonymous_variant 0.14
rpoC 764521 c.1152T>C synonymous_variant 0.11
rpoC 764539 c.1170C>G synonymous_variant 0.11
rpoC 764560 c.1191T>C synonymous_variant 0.15
rpoC 764575 c.1206T>G synonymous_variant 0.15
rpoC 764578 c.1209C>G synonymous_variant 0.15
rpoC 764581 c.1212T>C synonymous_variant 0.15
rpoC 764582 p.Leu405Met missense_variant 0.15
rpoC 764602 c.1233C>A synonymous_variant 0.2
rpoC 764605 c.1236G>T synonymous_variant 0.2
rpoC 764611 c.1242G>T synonymous_variant 0.19
rpoC 764626 c.1257C>T synonymous_variant 0.19
rpoC 764635 c.1266C>G synonymous_variant 0.24
rpoC 764650 c.1281G>T synonymous_variant 0.25
rpoC 764662 c.1293G>C synonymous_variant 0.25
rpoC 764668 c.1299C>T synonymous_variant 0.28
rpoC 764677 c.1308C>G synonymous_variant 0.29
rpoC 764678 p.Lys437His missense_variant 0.29
rpoC 764705 p.Leu446Thr missense_variant 0.3
rpoC 764731 c.1362G>C synonymous_variant 0.27
rpoC 764746 c.1377G>T synonymous_variant 0.23
rpoC 764752 c.1383G>C synonymous_variant 0.24
rpoC 764755 c.1386C>T synonymous_variant 0.24
rpoC 764764 c.1395T>C synonymous_variant 0.23
rpoC 764767 c.1398G>T synonymous_variant 0.23
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.22
rpoC 764797 c.1428G>C synonymous_variant 0.2
rpoC 764803 c.1434C>T synonymous_variant 0.19
rpoC 764808 p.Arg480His missense_variant 0.17
rpoC 764812 c.1443C>G synonymous_variant 0.17
rpoC 764815 c.1446A>G synonymous_variant 0.17
rpoC 764827 c.1458G>C synonymous_variant 0.17
rpoC 764843 p.Ala492Thr missense_variant 0.14
rpoC 764854 c.1485G>C synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781406 c.-154_-153insC upstream_gene_variant 1.0
Rv1258c 1406569 p.Val258Leu missense_variant 0.12
Rv1258c 1406672 c.669G>T synonymous_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471889 n.44G>T non_coding_transcript_exon_variant 0.19
rrs 1471935 n.91_94delACTC non_coding_transcript_exon_variant 0.17
rrs 1471967 n.122G>A non_coding_transcript_exon_variant 0.31
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.3
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.3
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.29
rrs 1471980 n.135G>T non_coding_transcript_exon_variant 0.29
rrs 1471981 n.136C>G non_coding_transcript_exon_variant 0.29
rrs 1471983 n.138C>T non_coding_transcript_exon_variant 0.29
rrs 1472023 n.178G>C non_coding_transcript_exon_variant 0.23
rrs 1472030 n.185G>C non_coding_transcript_exon_variant 0.22
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.22
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.22
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.23
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.23
rrs 1472043 n.198T>G non_coding_transcript_exon_variant 0.23
rrs 1472054 n.210_212delCGC non_coding_transcript_exon_variant 0.24
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.24
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 0.24
rrs 1472065 n.220G>A non_coding_transcript_exon_variant 0.24
rrs 1472067 n.222G>C non_coding_transcript_exon_variant 0.24
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.24
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.23
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.23
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.3
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.28
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.34
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.41
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.47
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 0.38
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.44
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 0.39
rrs 1472245 n.400C>A non_coding_transcript_exon_variant 0.38
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.39
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 0.39
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.41
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.41
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.42
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.41
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.44
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.38
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.4
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.4
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.4
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 0.44
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.49
rrs 1472380 n.535G>A non_coding_transcript_exon_variant 0.57
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.6
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.54
rrs 1472431 n.586G>A non_coding_transcript_exon_variant 0.51
rrs 1472434 n.589_590insC non_coding_transcript_exon_variant 0.48
rrs 1472437 n.592T>C non_coding_transcript_exon_variant 0.47
rrs 1472438 n.594delC non_coding_transcript_exon_variant 0.47
rrs 1472443 n.598A>G non_coding_transcript_exon_variant 0.47
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.47
rrs 1472448 n.603T>G non_coding_transcript_exon_variant 0.47
rrs 1472451 n.606C>A non_coding_transcript_exon_variant 0.48
rrs 1472452 n.607G>C non_coding_transcript_exon_variant 0.48
rrs 1472460 n.615T>G non_coding_transcript_exon_variant 0.49
rrs 1472461 n.616G>T non_coding_transcript_exon_variant 0.5
rrs 1472464 n.619A>C non_coding_transcript_exon_variant 0.51
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.54
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.54
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.54
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.55
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.56
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.59
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.58
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.57
rrs 1472506 n.661A>T non_coding_transcript_exon_variant 0.56
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.67
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.2
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.29
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.34
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.33
rrs 1472572 n.727T>A non_coding_transcript_exon_variant 0.44
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.33
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.33
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.74
rrs 1472591 n.746G>A non_coding_transcript_exon_variant 0.34
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.43
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.45
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.29
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.49
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.49
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.67
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.51
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.22
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.51
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.51
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.2
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.5
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.5
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.5
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.22
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.49
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.23
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.49
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.49
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.43
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.39
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.27
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.28
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.26
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.39
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.38
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.38
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.35
rrs 1472851 n.1006A>G non_coding_transcript_exon_variant 0.35
rrs 1472854 n.1009G>A non_coding_transcript_exon_variant 0.37
rrs 1472856 n.1011T>C non_coding_transcript_exon_variant 0.37
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 0.42
rrs 1472865 n.1020C>T non_coding_transcript_exon_variant 0.36
rrs 1472868 n.1024delG non_coding_transcript_exon_variant 0.4
rrs 1472871 n.1027_1028insAG non_coding_transcript_exon_variant 0.43
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.4
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.43
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.42
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.52
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.48
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.45
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.47
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.47
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.46
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.47
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.47
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.47
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.47
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.58
rrs 1473047 n.1202C>T non_coding_transcript_exon_variant 0.57
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.59
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.59
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.6
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.64
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.65
rrs 1473091 n.1246G>A non_coding_transcript_exon_variant 0.66
rrs 1473093 n.1248C>A non_coding_transcript_exon_variant 0.67
rrs 1473094 n.1249T>G non_coding_transcript_exon_variant 0.69
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.69
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.69
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.68
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.68
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.7
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.69
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.65
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.66
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.67
rrs 1473157 n.1312C>T non_coding_transcript_exon_variant 0.65
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.7
rrs 1473164 n.1319C>A non_coding_transcript_exon_variant 0.7
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.54
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.46
rrs 1473280 n.1435G>T non_coding_transcript_exon_variant 0.35
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.34
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.13
rrs 1473298 n.1453A>G non_coding_transcript_exon_variant 0.31
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.38
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.31
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.12
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.12
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.16
rrl 1474171 n.514C>G non_coding_transcript_exon_variant 0.15
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.14
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.14
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.14
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.2
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.39
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.39
rrl 1474287 n.630T>A non_coding_transcript_exon_variant 0.4
rrl 1474290 n.633T>C non_coding_transcript_exon_variant 0.39
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.42
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.41
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.38
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.38
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.37
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.37
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.38
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.39
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.41
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.33
rrl 1474437 n.782_784delATA non_coding_transcript_exon_variant 0.31
rrl 1474444 n.787G>C non_coding_transcript_exon_variant 0.32
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.33
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.36
rrl 1474476 n.819C>G non_coding_transcript_exon_variant 0.61
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.61
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.62
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.61
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.58
rrl 1474520 n.863A>C non_coding_transcript_exon_variant 0.55
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.47
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.47
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.47
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.48
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.48
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.49
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.49
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.45
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.46
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.44
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.44
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.44
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.45
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.44
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.54
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.52
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.52
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.49
rrl 1474694 n.1037C>T non_coding_transcript_exon_variant 0.49
rrl 1474716 n.1059A>T non_coding_transcript_exon_variant 0.43
rrl 1474717 n.1060A>C non_coding_transcript_exon_variant 0.43
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.45
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.45
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.45
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.44
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.47
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.47
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.47
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.47
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.47
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.47
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.49
rrl 1474806 n.1149A>C non_coding_transcript_exon_variant 0.48
rrl 1474822 n.1165G>T non_coding_transcript_exon_variant 0.48
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.48
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.47
rrl 1474905 n.1248T>A non_coding_transcript_exon_variant 0.19
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.12
rrl 1475650 n.1993A>G non_coding_transcript_exon_variant 0.12
rrl 1475655 n.1998T>A non_coding_transcript_exon_variant 0.18
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.2
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.29
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.39
rrl 1475697 n.2040C>T non_coding_transcript_exon_variant 0.4
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.4
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.43
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.58
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.63
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.65
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.64
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.64
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.65
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.63
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.66
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.67
rrl 1475963 n.2306G>A non_coding_transcript_exon_variant 0.67
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.63
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.63
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.64
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.62
rrl 1475989 n.2332T>G non_coding_transcript_exon_variant 0.62
rrl 1475990 n.2333G>A non_coding_transcript_exon_variant 0.62
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.58
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.59
rrl 1476019 n.2362G>A non_coding_transcript_exon_variant 0.57
rrl 1476026 n.2369T>G non_coding_transcript_exon_variant 0.55
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.55
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.53
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.51
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.4
rrl 1476079 n.2422G>A non_coding_transcript_exon_variant 0.4
rrl 1476082 n.2425T>G non_coding_transcript_exon_variant 0.39
rrl 1476085 n.2429_2430delGC non_coding_transcript_exon_variant 0.4
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.4
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.41
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.4
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.38
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.4
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.4
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.35
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.35
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.44
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.43
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.43
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.39
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.3
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.23
rrl 1476234 n.2577G>A non_coding_transcript_exon_variant 0.32
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.22
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.19
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.19
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.19
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.19
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.55
rrl 1476267 n.2610G>A non_coding_transcript_exon_variant 0.19
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.44
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.44
rrl 1476276 n.2619C>T non_coding_transcript_exon_variant 0.18
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.36
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.36
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.18
rrl 1476288 n.2631T>C non_coding_transcript_exon_variant 0.19
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.43
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.35
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.18
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.44
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.44
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.36
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.37
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.2
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.41
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.41
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.19
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.42
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.43
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.21
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.43
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.43
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.44
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.45
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.64
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.64
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.64
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.34
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.57
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.31
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.23
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.28
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.37
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.52
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.52
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.52
rrl 1476534 n.2877A>T non_coding_transcript_exon_variant 0.22
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.28
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.28
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.49
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.22
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.36
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.52
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.3
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.27
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.28
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.42
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.15
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.15
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.15
rpsA 1833909 p.Asp123Ala missense_variant 1.0
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834222 c.681T>C synonymous_variant 0.17
rpsA 1834228 c.687C>T synonymous_variant 0.16
rpsA 1834234 c.693G>C synonymous_variant 0.15
rpsA 1834240 c.699T>A synonymous_variant 0.17
rpsA 1834243 c.702G>C synonymous_variant 0.17
rpsA 1834246 c.705G>C synonymous_variant 0.17
rpsA 1834249 c.708T>C synonymous_variant 0.18
rpsA 1834261 c.720A>G synonymous_variant 0.18
rpsA 1834264 c.723G>C synonymous_variant 0.17
rpsA 1834279 c.738C>T synonymous_variant 0.16
rpsA 1834286 p.Ser249Gly missense_variant 0.14
rpsA 1834294 c.753G>C synonymous_variant 0.14
rpsA 1834298 p.Gln253Thr missense_variant 0.12
rpsA 1834303 c.762T>G synonymous_variant 0.13
rpsA 1834327 c.786G>C synonymous_variant 0.13
rpsA 1834354 c.813G>C synonymous_variant 0.13
rpsA 1834361 c.820T>C synonymous_variant 0.13
rpsA 1834366 c.825A>G synonymous_variant 0.13
rpsA 1834375 c.834G>C synonymous_variant 0.13
rpsA 1834378 c.837T>C synonymous_variant 0.13
rpsA 1834387 c.846C>T synonymous_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918034 p.Val32Gly missense_variant 0.5
ndh 2102214 p.Ser277Pro missense_variant 0.1
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2222540 p.Gly209Ser missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518608 p.Met165Thr missense_variant 0.14
ahpC 2726399 c.207C>T synonymous_variant 0.15
ribD 2987172 p.Ser112Cys missense_variant 1.0
ribD 2987185 p.Gln116Leu missense_variant 1.0
Rv2752c 3065369 p.Gln275* stop_gained 0.15
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
rpoA 3877903 p.Ile202Thr missense_variant 0.13
clpC1 4039769 c.936C>G synonymous_variant 0.11
clpC1 4039775 c.930G>C synonymous_variant 0.11
clpC1 4039778 c.927A>G synonymous_variant 0.11
clpC1 4039781 c.924G>C synonymous_variant 0.14
clpC1 4039790 c.915C>T synonymous_variant 0.18
clpC1 4039796 c.909C>T synonymous_variant 0.21
clpC1 4039805 c.900C>T synonymous_variant 0.29
clpC1 4039808 c.897G>A synonymous_variant 0.29
clpC1 4039820 c.885T>G synonymous_variant 0.3
clpC1 4039826 c.879C>G synonymous_variant 0.3
clpC1 4039831 c.874T>C synonymous_variant 0.3
clpC1 4039838 p.Leu289Ile missense_variant 0.33
clpC1 4039850 c.855T>C synonymous_variant 0.32
clpC1 4039853 c.852G>C synonymous_variant 0.32
clpC1 4039865 c.840T>C synonymous_variant 0.3
clpC1 4039875 p.Asn277Arg missense_variant 0.28
clpC1 4039898 c.807C>G synonymous_variant 0.32
clpC1 4039904 c.801A>G synonymous_variant 0.32
clpC1 4039907 c.798G>A synonymous_variant 0.32
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.28
clpC1 4039931 c.774T>C synonymous_variant 0.28
clpC1 4039937 c.768G>C synonymous_variant 0.26
clpC1 4039946 c.759A>T synonymous_variant 0.23
clpC1 4039949 c.756G>C synonymous_variant 0.23
clpC1 4039952 c.753T>C synonymous_variant 0.23
clpC1 4039955 c.750G>C synonymous_variant 0.23
clpC1 4039958 c.747G>C synonymous_variant 0.23
clpC1 4039976 p.Lys243Thr missense_variant 0.2
clpC1 4039982 p.Thr241Ile missense_variant 0.17
clpC1 4039994 c.711G>A synonymous_variant 0.17
clpC1 4040002 p.His235Asn missense_variant 0.17
clpC1 4040003 c.702G>C synonymous_variant 0.17
clpC1 4040012 c.693G>A synonymous_variant 0.18
clpC1 4040015 c.690G>A synonymous_variant 0.18
clpC1 4040018 c.687G>C synonymous_variant 0.18
clpC1 4040272 p.Tyr145His missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4247818 c.1305C>T synonymous_variant 0.13
aftB 4267321 p.Asp506Asn missense_variant 0.17
aftB 4267647 p.Asp397Gly missense_variant 1.0
ethA 4328452 c.-979C>T upstream_gene_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0
gid 4408469 c.-267T>C upstream_gene_variant 0.11