TB-Profiler result

Run: ERR11465511
Summary

Run ID: ERR11465511

Sample name:

Date: 09-01-2024 23:53:23

Number of reads: 1362538

Percentage reads mapped: 80.98

Strain: lineage4.3.4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.2 Euro-American (LAM) LAM1;LAM4;LAM11 RD174 0.92
lineage4.3.4.2.1 Euro-American (LAM) LAM11 RD174 0.92
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5611 c.372C>T synonymous_variant 1.0
gyrB 6140 p.Val301Leu missense_variant 1.0
gyrA 6709 c.-593A>G upstream_gene_variant 0.2
gyrA 6724 c.-578G>C upstream_gene_variant 0.15
gyrA 6730 c.-572A>G upstream_gene_variant 0.19
gyrA 6745 c.-557T>C upstream_gene_variant 0.17
gyrA 6760 c.-542G>C upstream_gene_variant 0.15
gyrA 6775 c.-527G>T upstream_gene_variant 0.15
gyrA 6793 c.-509T>C upstream_gene_variant 0.2
gyrB 6797 p.Gly520Ser missense_variant 0.22
gyrA 6808 c.-494C>G upstream_gene_variant 0.27
gyrA 6811 c.-491C>T upstream_gene_variant 0.28
gyrA 6838 c.-464C>A upstream_gene_variant 0.25
gyrA 6841 c.-461T>C upstream_gene_variant 0.24
gyrA 6844 c.-458T>C upstream_gene_variant 0.25
gyrA 6856 c.-446T>C upstream_gene_variant 0.2
gyrA 6862 c.-440C>G upstream_gene_variant 0.15
gyrA 7355 c.54T>C synonymous_variant 0.16
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7406 c.105G>T synonymous_variant 0.29
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7760 c.459C>T synonymous_variant 0.23
gyrA 7763 c.462T>A synonymous_variant 0.23
gyrA 7784 c.483A>G synonymous_variant 0.29
gyrA 7793 c.492G>C synonymous_variant 0.24
gyrA 7796 c.495G>C synonymous_variant 0.23
gyrA 7799 c.498A>G synonymous_variant 0.23
gyrA 7802 c.501C>G synonymous_variant 0.23
gyrA 7814 c.513C>G synonymous_variant 0.2
gyrA 7832 c.531G>T synonymous_variant 0.25
gyrA 7835 c.534A>G synonymous_variant 0.28
gyrA 7841 c.540C>G synonymous_variant 0.33
gyrA 8619 c.1318T>C synonymous_variant 0.15
gyrA 8915 c.1614A>G synonymous_variant 0.17
gyrA 8930 c.1629C>T synonymous_variant 0.16
gyrA 8996 c.1695T>C synonymous_variant 0.26
gyrA 8998 p.Leu566Trp missense_variant 0.27
gyrA 9023 c.1722A>C synonymous_variant 0.23
gyrA 9029 c.1728T>G synonymous_variant 0.22
gyrA 9032 c.1731T>C synonymous_variant 0.22
gyrA 9038 c.1737C>G synonymous_variant 0.24
gyrA 9050 p.Asp583Glu missense_variant 0.21
gyrA 9056 c.1755C>G synonymous_variant 0.21
gyrA 9062 c.1761C>G synonymous_variant 0.2
gyrA 9068 c.1767G>C synonymous_variant 0.23
gyrA 9080 c.1779G>T synonymous_variant 0.3
gyrA 9089 c.1788G>C synonymous_variant 0.3
gyrA 9092 c.1791C>G synonymous_variant 0.3
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.26
gyrA 9114 p.Glu605Asn missense_variant 0.24
gyrA 9119 c.1818A>G synonymous_variant 0.21
gyrA 9128 c.1827C>G synonymous_variant 0.2
gyrA 9304 p.Gly668Glu missense_variant 1.0
gyrA 9332 p.Asn677Lys missense_variant 0.35
gyrA 9335 c.2034G>C synonymous_variant 0.32
gyrA 9341 c.2040C>G synonymous_variant 0.26
gyrA 9345 c.2044A>C synonymous_variant 0.27
gyrA 9353 c.2052G>C synonymous_variant 0.25
gyrA 9356 c.2055G>C synonymous_variant 0.25
mshA 575782 c.435G>C synonymous_variant 0.23
mshA 575821 c.474G>C synonymous_variant 0.21
mshA 575842 c.495G>C synonymous_variant 0.17
mshA 575845 c.498C>G synonymous_variant 0.19
ccsA 620694 c.804C>G synonymous_variant 0.24
ccsA 620712 c.822G>C synonymous_variant 0.21
ccsA 620718 c.828G>C synonymous_variant 0.22
ccsA 620721 c.831G>C synonymous_variant 0.23
ccsA 620733 c.843G>C synonymous_variant 0.26
ccsA 620736 c.846G>C synonymous_variant 0.26
ccsA 620739 c.849A>G synonymous_variant 0.24
ccsA 620745 c.855G>C synonymous_variant 0.24
ccsA 620748 c.858T>G synonymous_variant 0.24
ccsA 620769 c.879C>G synonymous_variant 0.25
rpoB 760181 c.375T>C synonymous_variant 0.24
rpoB 760184 c.378A>G synonymous_variant 0.24
rpoB 760196 c.390C>G synonymous_variant 0.2
rpoB 760199 c.393C>G synonymous_variant 0.19
rpoB 760415 c.609C>T synonymous_variant 0.21
rpoB 760424 c.618C>G synonymous_variant 0.26
rpoB 760430 c.624T>C synonymous_variant 0.33
rpoB 760508 c.702G>C synonymous_variant 0.21
rpoB 760511 c.705G>C synonymous_variant 0.18
rpoB 760522 p.Ser239Asn missense_variant 0.21
rpoB 760547 c.741G>C synonymous_variant 0.21
rpoB 760551 c.745_746delTCinsAG synonymous_variant 0.21
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 0.22
rpoB 760625 c.819C>G synonymous_variant 0.31
rpoB 760646 c.840C>G synonymous_variant 0.2
rpoB 760655 c.849A>G synonymous_variant 0.18
rpoB 760670 c.864G>C synonymous_variant 0.19
rpoB 760674 c.868T>C synonymous_variant 0.21
rpoB 760679 c.873A>G synonymous_variant 0.18
rpoB 760683 c.877T>C synonymous_variant 0.21
rpoB 761300 c.1494G>C synonymous_variant 0.2
rpoB 761318 c.1512G>C synonymous_variant 0.24
rpoB 761327 c.1521A>G synonymous_variant 0.24
rpoB 761633 c.1827G>C synonymous_variant 0.31
rpoB 761636 c.1830G>T synonymous_variant 0.31
rpoB 761648 c.1842T>C synonymous_variant 0.24
rpoB 762083 c.2277T>C synonymous_variant 0.19
rpoB 762086 c.2280G>C synonymous_variant 0.2
rpoC 762983 c.-387C>T upstream_gene_variant 0.19
rpoC 762995 c.-375G>C upstream_gene_variant 0.15
rpoC 763028 c.-342T>C upstream_gene_variant 0.22
rpoC 763031 c.-339T>C upstream_gene_variant 0.22
rpoC 763040 c.-330C>G upstream_gene_variant 0.24
rpoC 763058 c.-312C>G upstream_gene_variant 0.35
rpoC 763070 c.-300T>C upstream_gene_variant 0.39
rpoC 763082 c.-288C>G upstream_gene_variant 0.35
rpoC 763103 c.-267G>C upstream_gene_variant 0.38
rpoC 763115 c.-255T>C upstream_gene_variant 0.29
rpoC 763127 c.-243G>C upstream_gene_variant 0.29
rpoC 763142 c.-228C>G upstream_gene_variant 0.15
rpoC 763160 c.-210G>T upstream_gene_variant 0.25
rpoC 763166 c.-204A>G upstream_gene_variant 0.24
rpoC 763486 c.117T>C synonymous_variant 0.19
rpoC 763501 c.132C>T synonymous_variant 0.15
rpoC 763528 c.159G>A synonymous_variant 0.15
rpoC 763570 c.201G>C synonymous_variant 0.24
rpoC 763573 c.204G>C synonymous_variant 0.24
rpoC 763594 c.225C>T synonymous_variant 0.32
rpoC 763675 c.306C>G synonymous_variant 0.15
rpoC 764491 c.1122G>C synonymous_variant 0.15
rpoC 764497 c.1128A>G synonymous_variant 0.14
rpoC 764500 c.1131C>G synonymous_variant 0.16
rpoC 764650 c.1281G>T synonymous_variant 0.19
rpoC 764677 c.1308C>G synonymous_variant 0.17
rpoC 764701 c.1332C>G synonymous_variant 0.26
rpoC 764716 c.1347G>C synonymous_variant 0.24
rpoC 764746 c.1377G>T synonymous_variant 0.14
rpoC 764752 c.1383G>C synonymous_variant 0.17
rpoC 764758 c.1389C>G synonymous_variant 0.15
rpoC 764764 c.1395T>C synonymous_variant 0.17
rpoC 764800 c.1431G>A synonymous_variant 0.16
rpoC 764803 c.1434C>T synonymous_variant 0.16
rpoC 764824 c.1455T>C synonymous_variant 0.16
rpoC 764857 c.1488G>T synonymous_variant 0.2
rpoC 764858 c.1489T>C synonymous_variant 0.2
rpoC 764878 c.1509C>G synonymous_variant 0.27
rpoC 764995 c.1626C>G synonymous_variant 0.95
rpoC 765478 c.2109T>C synonymous_variant 0.27
rpoC 765480 p.Tyr704Phe missense_variant 0.27
rpoC 765493 c.2124G>C synonymous_variant 0.28
rpoC 765499 c.2130C>A synonymous_variant 0.3
rpoC 765904 c.2535C>G synonymous_variant 0.29
rpoC 765937 c.2568T>C synonymous_variant 0.13
rpoC 766003 c.2634G>C synonymous_variant 0.21
rpoC 766009 c.2640G>T synonymous_variant 0.25
rpoC 766012 c.2643C>G synonymous_variant 0.23
rpoC 766459 c.3090G>C synonymous_variant 0.23
rpoC 766471 c.3102G>C synonymous_variant 0.21
rpoC 766483 c.3114G>C synonymous_variant 0.19
rpoC 766486 c.3117A>G synonymous_variant 0.19
rpoC 766492 c.3123T>G synonymous_variant 0.2
rpoC 766493 p.Gly1042Asn missense_variant 0.2
rpoC 766517 p.Thr1050Ser missense_variant 0.22
rpoC 766525 c.3156G>T synonymous_variant 0.2
rpoC 766528 c.3159T>G synonymous_variant 0.21
rpoC 766530 p.Arg1054Gln missense_variant 0.2
rpoC 766540 p.Asp1057Glu missense_variant 0.23
rpoC 766543 c.3174C>T synonymous_variant 0.23
rpoC 766549 c.3180G>C synonymous_variant 0.19
rpoC 766570 c.3201T>C synonymous_variant 0.21
rpoC 766573 c.3204T>G synonymous_variant 0.22
rpoC 766582 c.3213C>T synonymous_variant 0.24
rpoC 766585 c.3216T>C synonymous_variant 0.24
rpoC 766607 p.Ile1080Leu missense_variant 0.26
rpoC 766618 c.3249G>T synonymous_variant 0.25
rpoC 766624 c.3255G>C synonymous_variant 0.24
rpoC 766630 c.3261G>T synonymous_variant 0.24
rpoC 766634 p.Phe1089Ile missense_variant 0.25
rpoC 766645 c.3276A>G synonymous_variant 0.16
rpoC 766672 c.3303T>C synonymous_variant 0.2
rpoC 766690 c.3321G>C synonymous_variant 0.26
rpoC 766694 p.Gln1109Asp missense_variant 0.26
rpoC 766702 c.3333G>C synonymous_variant 0.26
rpoC 766708 c.3339A>G synonymous_variant 0.24
rpoC 766711 c.3342C>T synonymous_variant 0.24
rpoC 766720 c.3351C>T synonymous_variant 0.19
rpoC 766726 c.3357T>C synonymous_variant 0.26
rpoC 766732 c.3363G>T synonymous_variant 0.27
rpoC 766738 c.3369G>T synonymous_variant 0.28
rpoC 766747 c.3378C>T synonymous_variant 0.29
rpoC 766750 c.3381C>G synonymous_variant 0.31
rpoC 766753 c.3384C>T synonymous_variant 0.32
rpoC 766765 c.3396A>C synonymous_variant 0.3
rpoC 766774 c.3405T>C synonymous_variant 0.35
rpoC 766776 p.Arg1136His missense_variant 0.35
rpoC 766798 c.3429C>G synonymous_variant 0.28
rpoC 766804 c.3435A>G synonymous_variant 0.22
rpoC 766807 c.3438T>C synonymous_variant 0.22
rpoC 766837 c.3468G>C synonymous_variant 0.28
rpoC 767180 p.Ala1271Gln missense_variant 0.17
rpoC 767191 c.3822C>G synonymous_variant 0.16
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775915 p.Ala856Ser missense_variant 0.2
mmpL5 775916 c.2565T>C synonymous_variant 0.26
mmpL5 775922 c.2559G>C synonymous_variant 0.27
mmpL5 775943 c.2538C>G synonymous_variant 0.14
mmpL5 775946 c.2535C>G synonymous_variant 0.31
mmpL5 775951 c.2530C>T synonymous_variant 0.45
mmpL5 775966 p.Ala839Ser missense_variant 0.36
mmpL5 775975 p.Leu836Met missense_variant 0.38
mmpL5 775981 p.Leu834Met missense_variant 0.3
mmpL5 775991 c.2490G>A synonymous_variant 0.25
mmpL5 775997 c.2484T>G synonymous_variant 0.24
mmpL5 776000 p.Leu827Ile missense_variant 0.24
mmpL5 776009 c.2472A>G synonymous_variant 0.28
mmpL5 776021 c.2460G>A synonymous_variant 0.4
mmpL5 776024 c.2457G>C synonymous_variant 0.41
mmpL5 776030 c.2451G>C synonymous_variant 0.43
mmpL5 776060 c.2421C>G synonymous_variant 0.28
mmpL5 776072 c.2409C>G synonymous_variant 0.21
mmpL5 776075 c.2406C>G synonymous_variant 0.21
mmpL5 776080 p.Ala801Ser missense_variant 0.27
mmpL5 776645 c.1836C>G synonymous_variant 0.18
mmpL5 776650 p.Asp611Asn missense_variant 0.2
mmpL5 776654 c.1827A>C synonymous_variant 0.19
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781631 c.72G>C synonymous_variant 0.18
rpsL 781655 c.96T>C synonymous_variant 0.21
rpsL 781658 c.99A>G synonymous_variant 0.22
rpsL 781676 c.117C>G synonymous_variant 0.24
rpsL 781682 c.123T>C synonymous_variant 0.24
rpsL 781709 c.150G>C synonymous_variant 0.25
rpsL 781715 c.156T>C synonymous_variant 0.24
rpsL 781718 c.159C>G synonymous_variant 0.24
rpsL 781728 c.169T>C synonymous_variant 0.26
rpsL 781733 c.174G>C synonymous_variant 0.31
rpsL 781736 c.177T>C synonymous_variant 0.33
rpsL 781751 c.192G>C synonymous_variant 0.35
rpsL 781754 c.195G>A synonymous_variant 0.36
rpsL 781760 c.201T>C synonymous_variant 0.36
rpsL 781766 c.207C>T synonymous_variant 0.32
rpsL 781811 c.252C>T synonymous_variant 0.17
rpsL 781814 c.255C>T synonymous_variant 0.15
rpsL 781865 c.306G>C synonymous_variant 0.2
rpsL 781868 c.309T>C synonymous_variant 0.2
rpsL 781871 c.312G>C synonymous_variant 0.2
rpsL 781880 c.321C>G synonymous_variant 0.27
rpsL 781892 c.333A>G synonymous_variant 0.26
rpsL 781895 c.336G>A synonymous_variant 0.25
rpsL 781898 c.339A>G synonymous_variant 0.24
rpsL 781907 c.348T>C synonymous_variant 0.24
rpsL 781916 c.357T>C synonymous_variant 0.28
rpsL 781929 p.Gly124Ser missense_variant 0.28
rplC 800612 c.-197A>G upstream_gene_variant 0.16
rplC 800618 c.-191T>C upstream_gene_variant 0.2
rplC 800654 c.-155T>C upstream_gene_variant 0.19
rplC 800672 c.-137G>T upstream_gene_variant 0.21
rplC 800690 c.-119C>T upstream_gene_variant 0.21
rplC 800693 c.-116A>T upstream_gene_variant 0.21
rplC 800715 c.-94A>C upstream_gene_variant 0.23
rplC 800720 c.-89T>C upstream_gene_variant 0.24
rplC 800723 c.-86C>G upstream_gene_variant 0.22
rplC 800738 c.-71T>C upstream_gene_variant 0.17
fbiC 1303531 p.Met201Leu missense_variant 0.21
fbiC 1303548 c.618G>C synonymous_variant 0.17
fbiC 1303551 c.621G>T synonymous_variant 0.18
fbiC 1304613 c.1683T>G synonymous_variant 0.16
atpE 1461050 c.6C>T synonymous_variant 0.17
atpE 1461056 c.12T>A synonymous_variant 0.16
atpE 1461089 c.45G>C synonymous_variant 0.21
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.33
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.21
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 0.21
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.21
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.21
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.22
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.23
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.43
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.41
rrl 1474287 n.630_635delTCCTTTinsCTCGACTTG non_coding_transcript_exon_variant 0.27
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 0.28
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.28
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.26
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.35
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.35
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.37
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.22
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.23
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.24
rrl 1474708 n.1052_1053insACAAG non_coding_transcript_exon_variant 0.52
rrl 1474711 n.1055_1058delGTGT non_coding_transcript_exon_variant 0.5
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.5
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.5
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.47
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.46
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.51
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.45
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.28
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.53
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.48
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.48
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.4
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.33
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.33
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.54
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.5
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.5
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.5
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.5
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.46
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.41
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.45
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 0.44
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.33
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.26
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.25
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.25
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.25
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.24
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.25
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.24
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.24
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.26
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.21
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.23
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.32
inhA 1674864 c.663C>T synonymous_variant 0.37
inhA 1674870 c.669T>C synonymous_variant 0.35
inhA 1674876 c.675C>G synonymous_variant 0.33
inhA 1674879 c.678T>G synonymous_variant 0.32
inhA 1674904 p.Ala235Pro missense_variant 0.21
rpsA 1833745 c.204G>T synonymous_variant 0.15
rpsA 1833772 c.231C>T synonymous_variant 0.3
rpsA 1833778 c.237C>T synonymous_variant 0.28
rpsA 1833781 c.240T>G synonymous_variant 0.25
rpsA 1833790 c.249T>C synonymous_variant 0.17
rpsA 1833793 c.252C>T synonymous_variant 0.17
rpsA 1833808 c.267G>C synonymous_variant 0.23
rpsA 1833811 c.270G>T synonymous_variant 0.21
rpsA 1833820 c.279G>A synonymous_variant 0.24
rpsA 1833832 c.291G>A synonymous_variant 0.2
rpsA 1833838 c.297G>C synonymous_variant 0.19
rpsA 1833841 c.300C>G synonymous_variant 0.19
rpsA 1833928 c.387G>C synonymous_variant 0.2
rpsA 1833949 c.408T>C synonymous_variant 0.24
rpsA 1833970 c.429G>C synonymous_variant 0.22
rpsA 1833976 c.435C>T synonymous_variant 0.25
rpsA 1833979 c.438T>C synonymous_variant 0.25
rpsA 1833991 c.450C>A synonymous_variant 0.28
rpsA 1834000 c.459G>C synonymous_variant 0.23
rpsA 1834009 c.468C>T synonymous_variant 0.2
rpsA 1834012 c.471G>C synonymous_variant 0.2
rpsA 1834261 c.720A>G synonymous_variant 0.19
rpsA 1834264 c.723G>C synonymous_variant 0.22
rpsA 1834282 c.741C>T synonymous_variant 0.16
rpsA 1834303 c.762T>G synonymous_variant 0.15
rpsA 1834306 c.765T>C synonymous_variant 0.15
rpsA 1834348 c.807T>C synonymous_variant 0.23
rpsA 1834361 c.820T>C synonymous_variant 0.27
rpsA 1834366 c.825A>G synonymous_variant 0.27
rpsA 1834378 c.837T>C synonymous_variant 0.28
rpsA 1834387 c.846C>T synonymous_variant 0.27
rpsA 1834396 c.855G>C synonymous_variant 0.29
rpsA 1834411 c.870T>C synonymous_variant 0.18
rpsA 1834423 c.882G>C synonymous_variant 0.31
rpsA 1834543 c.1002C>G synonymous_variant 0.16
rpsA 1834600 c.1059G>C synonymous_variant 0.33
rpsA 1834606 c.1065C>T synonymous_variant 0.32
rpsA 1834609 c.1068T>C synonymous_variant 0.34
rpsA 1834619 c.1078T>C synonymous_variant 0.42
rpsA 1834633 c.1092A>G synonymous_variant 0.42
rpsA 1834639 c.1098T>C synonymous_variant 0.4
rpsA 1834666 c.1125G>C synonymous_variant 0.19
rpsA 1834667 p.Ala376Ser missense_variant 0.19
rpsA 1834678 c.1137C>T synonymous_variant 0.19
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518651 c.537C>G synonymous_variant 0.24
kasA 2518656 p.Ala181Gly missense_variant 0.24
kasA 2518672 c.558G>C synonymous_variant 0.29
kasA 2518678 c.564C>T synonymous_variant 0.3
kasA 2518711 c.597A>G synonymous_variant 0.25
kasA 2519137 c.1023T>G synonymous_variant 0.5
kasA 2519143 c.1029G>C synonymous_variant 0.37
kasA 2519152 c.1038G>C synonymous_variant 0.37
kasA 2519158 c.1044C>G synonymous_variant 0.32
Rv2752c 3065249 c.943T>C synonymous_variant 0.31
thyX 3067685 c.261A>G synonymous_variant 0.21
thyX 3067688 c.258G>C synonymous_variant 0.21
thyA 3073868 p.Thr202Ala missense_variant 0.91
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
alr 3840719 c.702A>G synonymous_variant 1.0
rpoA 3877656 c.852T>G synonymous_variant 0.17
rpoA 3877818 c.690A>G synonymous_variant 0.21
rpoA 3877836 c.672A>G synonymous_variant 0.24
rpoA 3877839 c.669G>T synonymous_variant 0.25
rpoA 3877842 c.666A>G synonymous_variant 0.23
rpoA 3877848 c.660C>T synonymous_variant 0.25
rpoA 3877856 c.652T>C synonymous_variant 0.27
rpoA 3877875 c.633T>G synonymous_variant 0.29
rpoA 3877881 c.627G>C synonymous_variant 0.25
rpoA 3877884 c.624G>C synonymous_variant 0.25
rpoA 3877893 c.615C>T synonymous_variant 0.26
rpoA 3877900 p.Ser203Thr missense_variant 0.24
rpoA 3877905 c.603A>G synonymous_variant 0.23
rpoA 3877908 c.600T>C synonymous_variant 0.22
rpoA 3877920 c.588G>C synonymous_variant 0.19
rpoA 3877926 c.582G>C synonymous_variant 0.22
rpoA 3877962 c.546G>C synonymous_variant 0.15
rpoA 3877971 p.Asp179Glu missense_variant 0.17
rpoA 3877989 c.519A>G synonymous_variant 0.2
rpoA 3878118 c.390T>C synonymous_variant 0.17
rpoA 3878130 c.378C>G synonymous_variant 0.19
rpoA 3878142 p.Gly122Glu missense_variant 0.24
rpoA 3878157 c.351C>G synonymous_variant 0.24
rpoA 3878160 c.348C>G synonymous_variant 0.2
rpoA 3878163 c.345C>T synonymous_variant 0.2
rpoA 3878175 c.333G>C synonymous_variant 0.19
rpoA 3878187 c.321C>G synonymous_variant 0.17
rpoA 3878193 c.315T>C synonymous_variant 0.16
rpoA 3878202 c.306G>C synonymous_variant 0.18
rpoA 3878217 c.291A>G synonymous_variant 0.18
rpoA 3878247 c.261G>C synonymous_variant 0.16
rpoA 3878292 c.216T>C synonymous_variant 0.17
rpoA 3878298 c.210A>G synonymous_variant 0.17
rpoA 3878310 c.198G>T synonymous_variant 0.21
rpoA 3878313 c.195G>C synonymous_variant 0.21
rpoA 3878346 c.162T>C synonymous_variant 0.17
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4038551 c.2154C>G synonymous_variant 0.25
clpC1 4038640 p.Asp689Asn missense_variant 0.14
clpC1 4038671 c.2034T>G synonymous_variant 0.15
clpC1 4038683 c.2022T>C synonymous_variant 0.14
clpC1 4038701 c.2004G>C synonymous_variant 0.16
clpC1 4038704 c.2001T>C synonymous_variant 0.17
clpC1 4038707 c.1998C>G synonymous_variant 0.17
clpC1 4038710 c.1995G>C synonymous_variant 0.17
clpC1 4038713 c.1992T>C synonymous_variant 0.17
clpC1 4038749 c.1956C>T synonymous_variant 0.16
clpC1 4038767 c.1938G>T synonymous_variant 0.16
clpC1 4038773 c.1932T>C synonymous_variant 0.19
clpC1 4038782 c.1923G>C synonymous_variant 0.17
clpC1 4038791 c.1914G>C synonymous_variant 0.15
clpC1 4038812 c.1893T>C synonymous_variant 0.19
clpC1 4038815 c.1890G>C synonymous_variant 0.19
clpC1 4038941 c.1764G>C synonymous_variant 0.15
clpC1 4039274 c.1431G>C synonymous_variant 0.23
clpC1 4039277 c.1428C>G synonymous_variant 0.21
clpC1 4039280 c.1425G>C synonymous_variant 0.21
clpC1 4039286 c.1419T>G synonymous_variant 0.19
clpC1 4039517 c.1188C>G synonymous_variant 0.18
clpC1 4040693 c.12A>T synonymous_variant 0.29
embC 4241039 p.Asp393Asn missense_variant 0.26
embC 4241047 c.1185C>T synonymous_variant 0.25
embC 4241050 c.1188T>G synonymous_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247500 c.987C>G synonymous_variant 0.16
embB 4247512 c.999T>C synonymous_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0