TB-Profiler result

Run: ERR9787030
Summary

Run ID: ERR9787030

Sample name:

Date: 2025-09-15T15:21:41.207042

Number of reads: 1918455

Percentage reads mapped: 79.84

Median coverage: 79.0

Strain: lineage6

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6 West-Africa 2 RD702 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6215 p.Ser326Thr missense_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6223 c.984G>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6250 c.1011A>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6286 c.1047T>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6292 c.1053G>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6295 c.1056A>G synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6307 c.1068T>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6319 c.1080G>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 6325 c.-977C>G upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6326 p.Ser363Ala missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6346 c.1107C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6388 c.-914T>C upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6397 c.1158G>A synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6403 c.-899T>C upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6416 p.Thr393Gly missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6427 c.-875T>C upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6430 c.-872A>G upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6440 p.Thr401Ala missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6445 p.Asp402Glu missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6446 p.Ala403Ser missense_variant 0.84 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6452 p.Val405Thr missense_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6469 c.-833T>G upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6472 c.-830G>C upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6475 c.-827C>G upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6478 c.-824G>C upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6481 c.-821G>T upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6484 c.-818A>G upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6487 c.1248C>G synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6490 c.-812T>C upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6496 c.-806G>C upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6499 c.-803A>G upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6508 c.-794A>G upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6511 c.-791A>T upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6541 c.1302C>T synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6547 c.-755T>C upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6550 c.-752A>C upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6551 c.1312T>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6577 c.1338T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6896 p.Arg553Lys missense_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7427 c.126G>C synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7451 c.150C>G synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7457 c.156T>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7472 c.171T>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 7475 c.174A>C synonymous_variant 0.13 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7490 c.189C>T synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7496 c.195C>G synonymous_variant 0.14 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7511 c.210C>T synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7514 c.213C>G synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7517 c.216G>A synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7526 c.225G>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7532 c.231T>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7568 c.267C>T synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7607 c.306C>G synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7631 c.330G>C synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7637 c.336C>G synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7658 c.357A>G synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7664 c.363T>C synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7670 c.369A>G synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7676 c.375G>C synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7679 c.378G>C synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7697 c.396C>G synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7700 c.399G>A synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7710 c.409T>C synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8493 p.Leu398Phe missense_variant 0.91 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13460 c.99T>C synonymous_variant 1.0 isoniazid Not assoc w R
Rv0010c 13482 p.Ala26Val missense_variant 1.0 isoniazid Not assoc w R
fgd1 491668 p.Lys296Glu missense_variant 0.99 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
Rv0565c 656432 p.Gly347Ser missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656609 p.Pro288Ser missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 760340 c.534G>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 0.15 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760475 c.669A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760502 c.696C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.17 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760534 p.Val243Ala missense_variant 0.14 rifampicin Uncertain significance
rpoB 760855 p.Thr350Ile missense_variant 0.98 rifampicin Uncertain significance
rpoB 760969 p.Ser388Leu missense_variant 0.9 rifampicin Not assoc w R
rpoB 761015 c.1209G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761087 c.1281C>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 761102 c.1296A>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 761147 c.1341C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 761165 c.1359G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 761171 c.1365C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 761217 p.Pro471Ala missense_variant 0.18 rifampicin Uncertain significance
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 761249 c.1443A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761723 p.Glu639Asp missense_variant 1.0 rifampicin Not assoc w R
rpoB 761792 c.1986T>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 762062 c.2256T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 762131 c.2325C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 762140 c.2334G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 762143 c.2337T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 762149 c.2343G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762249 c.2443C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 762275 c.2469C>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 762284 c.2478G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 762314 c.2508C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 762917 c.3111C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.78 rifampicin Not assoc w R
rpoB 763031 c.3225T>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 763528 c.159G>A synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 763711 c.342G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 763717 c.348T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 763732 c.363C>G synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 763735 c.366G>C synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 763741 c.372C>T synonymous_variant 0.3 rifampicin Uncertain significance
rpoC 763744 c.375G>C synonymous_variant 0.3 rifampicin Uncertain significance
rpoC 763765 c.396T>C synonymous_variant 0.35 rifampicin Uncertain significance
rpoC 763768 c.399C>T synonymous_variant 0.34 rifampicin Uncertain significance
rpoC 763774 c.405G>C synonymous_variant 0.34 rifampicin Uncertain significance
rpoC 763781 p.Ser138Glu missense_variant 0.35 rifampicin Uncertain significance
rpoC 763807 c.438T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.35 rifampicin Uncertain significance
rpoC 763816 c.447C>G synonymous_variant 0.35 rifampicin Uncertain significance
rpoC 763822 c.453C>G synonymous_variant 0.33 rifampicin Uncertain significance
rpoC 763831 c.462A>G synonymous_variant 0.32 rifampicin Uncertain significance
rpoC 763837 c.468G>C synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 763840 c.471G>C synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 763849 c.480G>A synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 763855 c.486C>T synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 763858 c.489A>G synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763867 c.498C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763870 c.501C>T synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 763871 p.Gly168Ser missense_variant 0.22 rifampicin Uncertain significance
rpoC 763876 p.Glu169Asp missense_variant 0.22 rifampicin Uncertain significance
rpoC 763879 c.510A>G synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763888 c.519G>T synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 763894 c.525A>G synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 763900 c.531G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763910 p.Leu181Met missense_variant 0.27 rifampicin Uncertain significance
rpoC 763933 c.564C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.24 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763947 p.Ala193Val missense_variant 0.24 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 764005 c.636G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 764032 p.Asp221Glu missense_variant 0.2 rifampicin Uncertain significance
rpoC 764040 p.Ser224Asn missense_variant 0.22 rifampicin Uncertain significance
rpoC 764044 c.675T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764059 c.690G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764084 p.Asn239Asp missense_variant 0.14 rifampicin Uncertain significance
rpoC 764242 c.873C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 764248 c.879C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764338 c.969G>A synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 764431 c.1062G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764452 c.1083T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764458 c.1089G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764491 c.1122G>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 764497 c.1128A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 764521 c.1152T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 764585 c.1216_1218delCTCinsTTG synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 764611 c.1242G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764686 c.1317C>T synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 764713 c.1344G>A synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 764746 c.1377G>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.22 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764857 c.1488G>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 764858 c.1489T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764887 c.1518G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 764893 c.1524T>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 764911 c.1542A>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 764948 c.1579T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 765079 c.1710T>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765886 c.2517C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 765892 c.2523T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 765937 c.2568T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 765947 c.2578T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766231 c.2862T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766486 c.3117A>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 766492 c.3123T>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 766494 p.Gly1042Asp missense_variant 0.15 rifampicin Uncertain significance
rpoC 766996 c.3627C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>T synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 767023 c.3654C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rplC 800232 c.-577G>T upstream_gene_variant 1.0 linezolid Uncertain significance
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 isoniazid Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rifampicin Not assoc w R
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304817 c.1887T>C synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304835 c.1905G>A synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
Rv1258c 1406685 p.Val219Ala missense_variant 1.0 isoniazid Uncertain significance
pyrazinamide Uncertain significance
streptomycin Uncertain significance
embR 1416633 p.Leu239Val missense_variant 1.0 ethambutol Uncertain significance
embR 1417554 c.-207C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
atpE 1461251 c.207G>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.25 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.18 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472297 n.453_454delGT non_coding_transcript_exon_variant 0.16 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472303 n.458_470delGGTTCTCTCGGATinsTGAGG non_coding_transcript_exon_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.31 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.29 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.3 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.32 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.2 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.2 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473289 n.1444T>G non_coding_transcript_exon_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473290 n.1445_1446insAA non_coding_transcript_exon_variant 0.16 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrl 1473596 n.-62G>A upstream_gene_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474452 n.795C>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053delTinsACAA non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474955 n.1298T>A non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474956 n.1299C>G non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474957 n.1301_1306delACCTTG non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474990 n.1333C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474991 n.1334T>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474995 n.1338T>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474997 n.1340A>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474999 n.1342C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475008 n.1351C>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475009 n.1352G>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475015 n.1358_1360delCCGinsTTCA non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475707 n.2050T>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.33 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476058 n.2401T>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
inhA 1674434 p.Val78Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid Not assoc w R
inhA 1674750 c.549T>G synonymous_variant 0.13 ethionamide Uncertain significance
isoniazid Uncertain significance
rpsA 1833874 c.333T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1833928 c.387G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833949 c.408T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833970 c.429G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833979 c.438T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834378 c.837T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834408 c.867C>T synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834411 c.870T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834423 c.882G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834432 c.891G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834435 c.894G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834451 c.910T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>G synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834465 c.924T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834489 c.948T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834520 p.Ala327Ser missense_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834543 c.1002C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834546 c.1005T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834555 c.1014T>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834556 p.Ala339Gln missense_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834609 c.1068T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834619 c.1078T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834666 c.1125G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834667 p.Ala376Ser missense_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834690 c.1149T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.14 linezolid Uncertain significance
tsnR 1853387 c.-219T>G upstream_gene_variant 0.15 linezolid Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 0.98 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2062922 p.Ile603Val missense_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
streptomycin Not assoc w R
bacA 2063121 c.1608A>T synonymous_variant 1.0 amikacin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
bacA 2063303 c.1426C>T synonymous_variant 1.0 amikacin Not assoc w R - Interim
capreomycin Uncertain significance
kanamycin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2155503 c.609C>T synonymous_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid Uncertain significance
Rv2477c 2783077 c.966T>C synonymous_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
ald 3086728 c.-92C>T upstream_gene_variant 1.0 cycloserine Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
ald 3087084 c.266delA frameshift_variant 1.0 cycloserine Uncertain significance
Rv3236c 3612143 p.Arg325His missense_variant 1.0 pyrazinamide Uncertain significance
lpqB 3624350 c.561G>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3624486 p.Asp142Gly missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625183 c.-273G>C upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625186 c.-276T>A upstream_gene_variant 0.18 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625189 c.1425A>G synonymous_variant 0.17 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625198 c.-288C>G upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625204 c.-294G>C upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625207 c.-297C>G upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625222 c.1392T>C synonymous_variant 0.18 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625690 c.-780T>C upstream_gene_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625696 c.-786A>G upstream_gene_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625705 c.909C>G synonymous_variant 0.16 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.16 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
alr 3840637 p.Pro238Ser missense_variant 1.0 cycloserine Uncertain significance
rpoA 3877686 c.822A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3877740 c.768G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3877743 c.765T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877770 c.735_738delGTCAinsCAGC synonymous_variant 0.2 rifampicin Uncertain significance
rpoA 3877776 c.732T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877794 c.714G>T synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3877818 c.690A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3877866 c.642G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877872 c.636C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3877905 c.603A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.22 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877989 c.519A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878001 c.505_507delTCAinsAGC synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878019 c.489A>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878022 c.486T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878028 c.480G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878031 c.477T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878034 c.474A>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878040 c.468T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878050 p.Arg153Lys missense_variant 0.15 rifampicin Uncertain significance
rpoA 3878055 c.453A>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878061 c.447G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3878064 c.444G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3878070 c.438T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoA 3878082 c.426T>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878103 c.405A>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878106 c.402G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878118 c.390T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878124 c.384G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878127 c.381G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.2 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3878187 c.321C>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3878193 c.315T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3878253 c.255G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3878256 c.252G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3878264 p.Ser82Gly missense_variant 0.17 rifampicin Uncertain significance
rpoA 3878271 c.237T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878274 c.234G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878283 p.Glu75Asp missense_variant 0.17 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878313 c.195G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.14 rifampicin Uncertain significance
clpC1 4038596 c.2109A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038602 c.2103G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038613 p.Asn698His missense_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038647 c.2058T>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038653 c.2052C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038658 p.Lys683Gln missense_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038661 p.Ser682Thr missense_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038662 c.2043T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038679 p.Pro676Ala missense_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038683 c.2022T>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4038713 c.1992T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038773 c.1932T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038782 c.1923G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038790 c.1915C>T synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038815 c.1890G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038878 c.1827A>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4038908 c.1797C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4038914 c.1791G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4038923 c.1782A>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4038932 c.1773G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4038953 c.1752A>G synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4038956 c.1749T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4038965 c.1740T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4038971 c.1734T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4038974 c.1731T>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038989 c.1716T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4038997 c.1708T>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039022 c.1683A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039031 c.1674T>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039037 c.1668T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039046 c.1659C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039067 c.1638G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039070 c.1635G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039073 c.1632C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039079 c.1626C>G synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4039082 c.1623C>T synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039085 c.1620A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039097 c.1608G>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039103 c.1602T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039112 c.1593C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039121 c.1584T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039145 c.1560G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039169 c.1536A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039172 c.1533A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039610 c.1095G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039616 c.1089G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039622 c.1083C>A synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039646 c.1059G>A synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039661 c.1044T>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039664 c.1041G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039691 c.1014G>T synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039694 c.1011G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039724 c.981A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039748 c.957G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039751 c.954A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039757 c.948A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039760 c.945T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039766 c.939T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039769 c.936C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039778 c.927A>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039781 c.924G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039802 c.903G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039805 c.900C>T synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4039808 c.897G>A synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039925 c.780C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039931 c.774T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040021 c.684A>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040024 c.681A>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040105 c.600C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040225 c.480A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040228 c.477G>A synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040237 c.468C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040243 c.462C>T synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4040249 c.456A>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040267 c.438A>G synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
glpK 4138377 p.Val460Ala missense_variant 1.0 ethambutol Not assoc w R
isoniazid Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rifampicin Not assoc w R
streptomycin Not assoc w R
glpK 4139183 c.572dupG frameshift_variant 0.71 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4241843 p.Leu661Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244220 c.988C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244379 p.Pro383Ser missense_variant 1.0 ethambutol Not assoc w R
embB 4246864 c.351C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269351 c.483C>T synonymous_variant 1.0 ethambutol Not assoc w R
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269522 c.312C>T synonymous_variant 1.0 ethambutol Not assoc w R
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
ethA 4326465 p.Ile337Val missense_variant 1.0 ethionamide Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4408034 p.Glu57Lys missense_variant 1.0 streptomycin Uncertain significance