Run ID: ERR9786421
Sample name:
Date: 2024-10-04T20:41:45.593929
Number of reads: 814148
Percentage reads mapped: 69.99
Median coverage: 35.0
Strain: lineage4.1.2.1
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4.1 | Euro-American | None | 0.9 |
| lineage4.1.2 | Euro-American | None | 0.98 |
| lineage4.1.2.1 | Euro-American (Haarlem) | RD182 | 0.97 |
| La1.2.BCG | M.bovis | None | 0.06 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.His312Arg | Mutation from literature | |
| p.Leu359Ile | Uncertain significance | Mutation from literature | ||
| p.Tyr384Asn | Mutation from literature | |||
| p.Ala388Gly | Mutation from literature | |||
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.36 | streptomycin | Uncertain significance | Mutation from literature |
| embB | 4247448 | p.His312Arg | missense_variant | 0.3 | ethambutol | Mutation from literature | |
| embB | 4247588 | p.Leu359Ile | missense_variant | 0.23 | ethambutol | Uncertain significance | Mutation from literature |
| embB | 4247663 | p.Tyr384Asn | missense_variant | 0.2 | ethambutol | Mutation from literature | |
| embB | 4247676 | p.Ala388Gly | missense_variant | 0.24 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 708 | c.708T>C | synonymous_variant | 0.19 | isoniazid | |
| dnaA | 720 | c.720G>A | synonymous_variant | 0.19 | isoniazid | |
| dnaA | 741 | c.741T>C | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>G | synonymous_variant | 0.21 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 0.21 | isoniazid | |
| dnaA | 975 | c.975G>T | synonymous_variant | 0.18 | isoniazid | |
| dnaA | 984 | c.984T>C | synonymous_variant | 0.19 | isoniazid | Not assoc w R - Interim |
| dnaA | 996 | c.996A>G | synonymous_variant | 0.19 | isoniazid | |
| gyrB | 6238 | c.999G>A | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6242 | p.Arg335Lys | missense_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>G | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6256 | c.1017G>A | synonymous_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6265 | c.1026C>T | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6268 | c.1029C>G | synonymous_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6289 | c.1050C>T | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>C | synonymous_variant | 0.35 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6304 | c.-998C>G | upstream_gene_variant | 0.35 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6376 | c.-926G>A | upstream_gene_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6415 | c.-887G>C | upstream_gene_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6418 | c.-884C>G | upstream_gene_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6427 | c.-875T>C | upstream_gene_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6440 | p.Thr401Ala | missense_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6448 | c.-854G>C | upstream_gene_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6451 | c.-851A>G | upstream_gene_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6454 | c.-848C>G | upstream_gene_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6457 | c.-845T>G | upstream_gene_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6460 | c.-842G>C | upstream_gene_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6469 | c.-833T>G | upstream_gene_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6475 | c.-827C>G | upstream_gene_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6490 | c.-812T>G | upstream_gene_variant | 0.17 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6598 | c.-704C>G | upstream_gene_variant | 0.19 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6763 | c.1524G>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6775 | c.1536G>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Thr | missense_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6811 | c.1572C>T | synonymous_variant | 0.21 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6952 | c.1713C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7023 | p.Leu595Gln | missense_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7093 | c.-209T>G | upstream_gene_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7124 | p.Ser629Thr | missense_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>C | upstream_gene_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7186 | c.1947C>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7406 | c.105G>C | synonymous_variant | 0.19 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>A | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7562 | c.261C>T | synonymous_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7622 | c.321C>T | synonymous_variant | 0.34 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7625 | c.324G>C | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 0.34 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7673 | c.372G>A | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382_384delAGGinsCGC | synonymous_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7697 | c.396C>G | synonymous_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7710 | c.409_411delTTGinsCTC | synonymous_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 0.19 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>C | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7823 | c.522G>C | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8189 | c.888G>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8225 | c.924T>C | synonymous_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8270 | c.969G>T | synonymous_variant | 0.19 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8276 | c.975G>A | synonymous_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | p.Ile328Leu | missense_variant | 0.23 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8330 | c.1029C>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8337 | c.1036_1038delCTAinsTTG | synonymous_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8342 | c.1041G>C | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8357 | c.1056G>A | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8366 | c.1065G>T | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8367 | c.1066C>T | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8372 | c.1071G>C | synonymous_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8400 | p.Asp367Asn | missense_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8417 | c.1116C>G | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8423 | c.1122G>C | synonymous_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>C | synonymous_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8465 | c.1164C>G | synonymous_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8472 | c.1171C>T | synonymous_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>A | synonymous_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>C | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8528 | c.1227G>C | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8543 | c.1242C>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8553 | c.1252C>A | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8740 | p.Arg480His | missense_variant | 0.17 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9104 | c.1803C>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9122 | c.1821C>A | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 0.31 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9153 | p.Thr618Glu | missense_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9158 | c.1857C>T | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9161 | c.1860C>G | synonymous_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9176 | c.1875G>C | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9179 | c.1878C>T | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9191 | c.1890G>C | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9218 | c.1917C>T | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9224 | c.1923C>T | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9233 | c.1932C>G | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9239 | c.1938C>T | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 0.22 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| fgd1 | 490827 | c.45C>T | synonymous_variant | 0.18 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490848 | c.66A>G | synonymous_variant | 0.24 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 490851 | c.69A>T | synonymous_variant | 0.24 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490854 | c.72C>G | synonymous_variant | 0.24 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.24 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490887 | c.105G>A | synonymous_variant | 0.21 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490890 | c.108C>G | synonymous_variant | 0.23 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490896 | c.114C>T | synonymous_variant | 0.22 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490905 | c.123T>C | synonymous_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490917 | c.135C>G | synonymous_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490929 | c.147C>G | synonymous_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490932 | c.150T>C | synonymous_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490935 | c.153C>G | synonymous_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490948 | p.Ser56Ala | missense_variant | 0.18 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490962 | c.180T>G | synonymous_variant | 0.2 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491007 | c.225G>C | synonymous_variant | 0.22 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491013 | c.231C>G | synonymous_variant | 0.24 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491043 | c.261T>G | synonymous_variant | 0.3 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491049 | c.267T>C | synonymous_variant | 0.3 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.27 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491067 | c.285C>T | synonymous_variant | 0.27 | pretomanid | |
| delamanid | ||||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491077 | p.Asn99Gly | missense_variant | 0.21 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491082 | c.300T>C | synonymous_variant | 0.21 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491083 | p.Val101Ile | missense_variant | 0.21 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491091 | c.309T>C | synonymous_variant | 0.22 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491094 | c.312C>G | synonymous_variant | 0.22 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491097 | c.315G>C | synonymous_variant | 0.23 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 0.25 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 0.28 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491130 | c.348C>G | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.26 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491151 | c.369G>A | synonymous_variant | 0.28 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491184 | c.402A>G | synonymous_variant | 0.34 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.35 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491194 | c.412_414delCTAinsTTG | synonymous_variant | 0.35 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 0.36 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.26 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 0.26 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491256 | p.Lys158Asn | missense_variant | 0.71 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491313 | c.531C>T | synonymous_variant | 0.28 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491319 | c.537G>C | synonymous_variant | 0.26 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491325 | c.543G>C | synonymous_variant | 0.26 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491337 | c.555C>G | synonymous_variant | 0.27 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491340 | c.558C>G | synonymous_variant | 0.26 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491591 | p.Lys270Met | missense_variant | 0.77 | pretomanid | |
| delamanid | Uncertain significance | |||||
| clofazimine | Not assoc w R | |||||
| mshA | 575623 | c.276C>G | synonymous_variant | 0.32 | isoniazid | |
| ethionamide | ||||||
| mshA | 575629 | c.282A>G | synonymous_variant | 0.34 | isoniazid | |
| ethionamide | ||||||
| mshA | 575632 | c.285G>C | synonymous_variant | 0.34 | isoniazid | |
| ethionamide | ||||||
| mshA | 575635 | c.288A>C | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575638 | c.291T>C | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575641 | c.294A>G | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575647 | c.300G>C | synonymous_variant | 0.29 | isoniazid | |
| ethionamide | ||||||
| mshA | 575649 | p.Val101Ala | missense_variant | 0.29 | isoniazid | |
| ethionamide | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 0.31 | isoniazid | |
| ethionamide | ||||||
| mshA | 575662 | c.315C>G | synonymous_variant | 0.31 | isoniazid | |
| ethionamide | ||||||
| mshA | 575665 | c.318G>A | synonymous_variant | 0.31 | isoniazid | |
| ethionamide | ||||||
| mshA | 575674 | c.327G>C | synonymous_variant | 0.33 | isoniazid | |
| ethionamide | ||||||
| mshA | 575679 | p.Asn111Ser | missense_variant | 0.64 | isoniazid | Not assoc w R |
| ethionamide | Not assoc w R | |||||
| mshA | 575695 | c.348C>G | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575701 | c.354G>A | synonymous_variant | 0.29 | isoniazid | |
| ethionamide | ||||||
| mshA | 575704 | c.357T>G | synonymous_variant | 0.28 | isoniazid | |
| ethionamide | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 0.28 | isoniazid | |
| ethionamide | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 0.29 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 0.28 | isoniazid | |
| ethionamide | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575752 | c.405G>C | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575755 | c.408G>A | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575756 | c.409C>T | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575770 | c.423G>A | synonymous_variant | 0.28 | isoniazid | |
| ethionamide | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 0.27 | isoniazid | |
| ethionamide | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 0.29 | isoniazid | |
| ethionamide | ||||||
| mshA | 575812 | c.465C>T | synonymous_variant | 0.33 | isoniazid | |
| ethionamide | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 0.35 | isoniazid | |
| ethionamide | ||||||
| mshA | 575824 | c.477T>G | synonymous_variant | 0.34 | isoniazid | |
| ethionamide | ||||||
| mshA | 575830 | c.483C>G | synonymous_variant | 0.31 | isoniazid | |
| ethionamide | ||||||
| mshA | 575833 | c.486C>G | synonymous_variant | 0.31 | isoniazid | |
| ethionamide | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 0.36 | isoniazid | |
| ethionamide | ||||||
| mshA | 575875 | c.528C>G | synonymous_variant | 0.38 | isoniazid | |
| ethionamide | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 0.38 | isoniazid | |
| ethionamide | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 0.39 | isoniazid | |
| ethionamide | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 0.33 | isoniazid | |
| ethionamide | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 0.3 | isoniazid | |
| ethionamide | ||||||
| mshA | 575908 | c.561A>G | synonymous_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| ccsA | 619543 | c.-348C>G | upstream_gene_variant | 0.18 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.18 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.2 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.2 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.2 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.24 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.27 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619609 | c.-282G>C | upstream_gene_variant | 0.28 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.24 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619645 | c.-246G>C | upstream_gene_variant | 0.26 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620317 | p.Val143Leu | missense_variant | 0.22 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| Rv0565c | 657269 | p.Ser68Pro | missense_variant | 0.72 | ethionamide | Uncertain significance |
| hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.21 | isoniazid | |
| hadA | 732295 | c.366G>C | synonymous_variant | 0.45 | isoniazid | |
| hadA | 732305 | p.Ile126Val | missense_variant | 0.45 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 0.45 | isoniazid | |
| hadA | 732321 | p.Glu131Ala | missense_variant | 0.45 | isoniazid | |
| hadA | 732329 | p.Leu134Val | missense_variant | 0.45 | isoniazid | Uncertain significance |
| hadA | 732337 | c.408G>A | synonymous_variant | 0.45 | isoniazid | |
| hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.52 | isoniazid | |
| hadA | 732396 | p.Gly156Ala | missense_variant | 0.48 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 0.48 | isoniazid | |
| nusG | 734407 | p.Val52Ile | missense_variant | 0.31 | rifampicin | |
| nusG | 734421 | c.168A>G | synonymous_variant | 0.29 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 0.32 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 0.37 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 0.38 | rifampicin | |
| nusG | 734457 | c.204C>G | synonymous_variant | 0.39 | rifampicin | |
| nusG | 734472 | c.219T>C | synonymous_variant | 0.39 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| nusG | 734532 | c.279A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| nusG | 734556 | c.303C>T | synonymous_variant | 0.4 | rifampicin | |
| nusG | 734559 | c.306T>C | synonymous_variant | 0.41 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>C | synonymous_variant | 0.29 | rifampicin | |
| nusG | 734596 | c.343T>C | synonymous_variant | 0.27 | rifampicin | |
| nusG | 734601 | c.348C>G | synonymous_variant | 0.29 | rifampicin | |
| rpoB | 760101 | c.295T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoB | 760112 | c.306T>C | synonymous_variant | 0.39 | rifampicin | |
| rpoB | 760115 | c.309C>T | synonymous_variant | 0.61 | rifampicin | Not assoc w R |
| rpoB | 760118 | c.312T>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 0.47 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.43 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 0.62 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 0.51 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 0.51 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 0.51 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 0.51 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 760361 | c.555T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 0.46 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 0.46 | rifampicin | Uncertain significance |
| rpoB | 760380 | p.Thr192Leu | missense_variant | 0.44 | rifampicin | |
| rpoB | 760406 | c.600G>C | synonymous_variant | 0.5 | rifampicin | |
| rpoB | 760412 | c.606C>G | synonymous_variant | 0.52 | rifampicin | |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 0.5 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 0.49 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.51 | rifampicin | Uncertain significance |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.5 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 0.47 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoB | 760715 | c.909C>G | synonymous_variant | 0.42 | rifampicin | |
| rpoB | 760718 | c.912C>T | synonymous_variant | 0.42 | rifampicin | |
| rpoB | 760724 | c.918T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoB | 760751 | c.945G>C | synonymous_variant | 0.33 | rifampicin | |
| rpoB | 760757 | c.951T>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 760759 | p.Val318Ala | missense_variant | 0.29 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
| rpoB | 760949 | c.1143C>T | synonymous_variant | 0.23 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 0.28 | rifampicin | |
| rpoB | 761006 | c.1200C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 0.36 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 0.57 | rifampicin | |
| rpoB | 761129 | c.1323G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 761153 | c.1347G>C | synonymous_variant | 0.6 | rifampicin | |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 0.62 | rifampicin | |
| rpoB | 761213 | c.1407G>C | synonymous_variant | 0.6 | rifampicin | |
| rpoB | 761219 | c.1413G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 761306 | c.1500C>G | synonymous_variant | 0.45 | rifampicin | |
| rpoB | 761312 | c.1506G>C | synonymous_variant | 0.46 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 761330 | c.1524G>C | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 0.46 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 0.42 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 0.37 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 0.4 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 0.36 | rifampicin | |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 0.35 | rifampicin | |
| rpoB | 761438 | c.1632G>C | synonymous_variant | 0.35 | rifampicin | |
| rpoB | 761439 | p.Asp545Lys | missense_variant | 0.35 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 0.34 | rifampicin | |
| rpoB | 761447 | c.1641C>G | synonymous_variant | 0.34 | rifampicin | |
| rpoB | 761452 | p.Val549Glu | missense_variant | 0.33 | rifampicin | |
| rpoB | 761457 | p.Pro551Ser | missense_variant | 0.33 | rifampicin | |
| rpoB | 761477 | c.1671C>G | synonymous_variant | 0.32 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 0.35 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 0.31 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoB | 761588 | c.1782C>T | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 0.27 | rifampicin | |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoB | 761639 | c.1833G>A | synonymous_variant | 0.29 | rifampicin | |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 0.25 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 0.24 | rifampicin | |
| rpoB | 761720 | c.1914C>G | synonymous_variant | 0.24 | rifampicin | |
| rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 0.22 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 0.24 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 0.26 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 0.26 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 0.27 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 0.24 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 0.26 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 0.25 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 761815 | p.Ala670Glu | missense_variant | 0.3 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 0.4 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 0.45 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 0.45 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 0.48 | rifampicin | |
| rpoB | 761873 | c.2067A>C | synonymous_variant | 0.53 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 0.53 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 761915 | p.Asp703Glu | missense_variant | 0.49 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 0.49 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 0.5 | rifampicin | |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 0.4 | rifampicin | Uncertain significance |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 0.44 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 0.43 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 0.43 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 762206 | c.2400C>G | synonymous_variant | 0.46 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 762246 | c.2440C>T | synonymous_variant | 0.47 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 0.54 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoB | 762314 | c.2508C>T | synonymous_variant | 0.5 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 0.44 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 0.42 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 0.44 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.42 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.4 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.38 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.37 | rifampicin | |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.41 | rifampicin | |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.36 | rifampicin | |
| rpoB | 762488 | c.2682G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 762489 | p.Val895Gln | missense_variant | 0.28 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.29 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 0.29 | rifampicin | Uncertain significance |
| rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.29 | rifampicin | |
| rpoB | 762810 | p.Ala1002Ser | missense_variant | 0.28 | rifampicin | |
| rpoB | 762813 | p.Met1003Val | missense_variant | 0.31 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.6 | rifampicin | |
| rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.56 | rifampicin | |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
| rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.65 | rifampicin | |
| rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.6 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.56 | rifampicin | |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.44 | rifampicin | |
| rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.44 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.44 | rifampicin | |
| rpoB | 763214 | c.3408T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.45 | rifampicin | |
| rpoB | 763227 | c.3421C>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.39 | rifampicin | |
| rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.36 | rifampicin | |
| rpoB | 763268 | c.3462C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoB | 763283 | c.3477T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
| rpoC | 763284 | c.-86C>T | upstream_gene_variant | 0.29 | rifampicin | |
| rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.28 | rifampicin | Uncertain significance |
| rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.28 | rifampicin | Uncertain significance |
| rpoC | 763402 | c.33C>G | synonymous_variant | 0.31 | rifampicin | |
| rpoC | 763411 | c.42T>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 0.3 | rifampicin | |
| rpoC | 763441 | c.72C>T | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoC | 763633 | c.264T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 0.37 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 763774 | c.405G>C | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 763816 | c.447C>G | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 0.41 | rifampicin | |
| rpoC | 763853 | p.Val162Ile | missense_variant | 0.41 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 0.43 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 0.39 | rifampicin | |
| rpoC | 763877 | c.508_510delCTAinsTTG | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 763936 | c.567C>G | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 763945 | c.576T>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 763951 | c.582G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 763960 | c.591T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 763991 | p.Ile208Leu | missense_variant | 0.42 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 0.42 | rifampicin | |
| rpoC | 764040 | p.Ser224Thr | missense_variant | 0.4 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 764102 | p.Val245Ile | missense_variant | 0.38 | rifampicin | |
| rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.38 | rifampicin | |
| rpoC | 764116 | c.747C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 764131 | c.762T>C | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 764140 | c.771C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 764188 | c.819A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Ile | missense_variant | 0.4 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 0.36 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoC | 764215 | c.846A>G | synonymous_variant | 0.36 | rifampicin | |
| rpoC | 764236 | c.867G>A | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 764248 | c.879C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 764257 | c.888G>C | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 764338 | c.969G>A | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 764353 | c.984G>C | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 764419 | c.1050C>G | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 0.33 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 0.32 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 0.33 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoC | 764489 | c.1120C>T | synonymous_variant | 0.31 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 764510 | c.1141C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 0.33 | rifampicin | |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.33 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.31 | rifampicin | |
| rpoC | 765073 | c.1704G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>T | synonymous_variant | 0.34 | rifampicin | |
| rpoC | 765150 | p.Gly594Glu | missense_variant | 0.84 | rifampicin | Not assoc w R |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Ala | missense_variant | 0.21 | rifampicin | Uncertain significance |
| rpoC | 765329 | p.Ser654Gly | missense_variant | 0.21 | rifampicin | |
| rpoC | 765346 | c.1977C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 0.35 | rifampicin | Uncertain significance |
| rpoC | 765404 | p.Leu679Val | missense_variant | 0.4 | rifampicin | |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 0.53 | rifampicin | |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 765559 | c.2190G>C | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 765580 | c.2211G>C | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 765613 | p.His748Gln | missense_variant | 0.47 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 765631 | p.Asp754Glu | missense_variant | 0.44 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 0.4 | rifampicin | Uncertain significance |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 0.26 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
| rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 766027 | c.2658G>C | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 766030 | c.2661C>G | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 766036 | c.2667C>T | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 766043 | p.Gln892Glu | missense_variant | 0.23 | rifampicin | |
| rpoC | 766054 | c.2685C>G | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 766082 | p.Ala905Gln | missense_variant | 0.22 | rifampicin | |
| rpoC | 766096 | c.2727G>C | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 766135 | c.2766G>A | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoC | 766141 | c.2772C>T | synonymous_variant | 0.26 | rifampicin | |
| rpoC | 766142 | c.2773C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoC | 766258 | c.2889T>C | synonymous_variant | 0.3 | rifampicin | |
| rpoC | 766273 | c.2904T>C | synonymous_variant | 0.31 | rifampicin | |
| rpoC | 766274 | p.Ala969Thr | missense_variant | 0.31 | rifampicin | |
| rpoC | 766280 | p.Ser971Gly | missense_variant | 0.34 | rifampicin | |
| rpoC | 766288 | c.2919C>G | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 766303 | c.2934C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 766312 | c.2943T>G | synonymous_variant | 0.48 | rifampicin | |
| rpoC | 766327 | c.2958C>A | synonymous_variant | 0.53 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 0.51 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 766357 | c.2988C>T | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 0.53 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 766408 | c.3039C>G | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 766411 | c.3042C>G | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 0.56 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 766462 | c.3093G>C | synonymous_variant | 0.52 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 0.48 | rifampicin | |
| rpoC | 766484 | p.Val1039Ile | missense_variant | 0.49 | rifampicin | Uncertain significance |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 0.51 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 766531 | c.3162G>C | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.42 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 0.36 | rifampicin | |
| rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.36 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.38 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 0.37 | rifampicin | |
| rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.37 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 0.32 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 0.36 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 0.37 | rifampicin | |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 0.36 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 0.55 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.53 | rifampicin | |
| rpoC | 767014 | c.3645G>C | synonymous_variant | 0.55 | rifampicin | |
| rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.57 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.38 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 767263 | c.3894T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| clofazimine | Not assoc w R | |||||
| rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
| rpsL | 781649 | c.90T>C | synonymous_variant | 0.35 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 0.37 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 0.29 | streptomycin | |
| rpsL | 781700 | c.141G>C | synonymous_variant | 0.29 | streptomycin | |
| rpsL | 781703 | c.144G>T | synonymous_variant | 0.29 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 0.28 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 0.27 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 0.28 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 0.31 | streptomycin | |
| rpsL | 781748 | c.189C>G | synonymous_variant | 0.29 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 0.29 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 0.31 | streptomycin | |
| rpsL | 781772 | c.213C>A | synonymous_variant | 0.3 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.36 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 0.36 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 0.38 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 0.41 | streptomycin | |
| rpsL | 781841 | c.282C>G | synonymous_variant | 0.38 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 0.4 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 0.4 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 0.4 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 0.4 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 0.4 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 0.42 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 0.45 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 0.38 | streptomycin | Uncertain significance |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.21 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.21 | linezolid | |
| rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.23 | linezolid | |
| rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.24 | linezolid | |
| rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.24 | linezolid | |
| rplC | 800814 | c.6A>G | synonymous_variant | 0.24 | linezolid | |
| rplC | 800817 | c.9A>T | synonymous_variant | 0.27 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 0.28 | linezolid | |
| rplC | 800967 | c.159C>G | synonymous_variant | 0.24 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 0.24 | linezolid | Not assoc w R - Interim |
| rplC | 801195 | c.387G>C | synonymous_variant | 0.27 | linezolid | |
| rplC | 801207 | c.399C>T | synonymous_variant | 0.28 | linezolid | |
| rplC | 801246 | c.438C>T | synonymous_variant | 0.36 | linezolid | |
| rplC | 801249 | c.441T>C | synonymous_variant | 0.35 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 0.35 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 0.34 | linezolid | |
| rplC | 801267 | c.459A>T | synonymous_variant | 0.34 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 0.33 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 0.33 | linezolid | |
| rplC | 801279 | c.471G>C | synonymous_variant | 0.33 | linezolid | |
| rplC | 801282 | c.474G>C | synonymous_variant | 0.34 | linezolid | |
| rplC | 801285 | c.477G>C | synonymous_variant | 0.33 | linezolid | |
| rplC | 801300 | c.492C>G | synonymous_variant | 0.33 | linezolid | |
| rplC | 801309 | c.501C>G | synonymous_variant | 0.31 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 0.31 | linezolid | |
| rplC | 801321 | c.513C>T | synonymous_variant | 0.31 | linezolid | Not assoc w R - Interim |
| rplC | 801324 | c.516T>C | synonymous_variant | 0.36 | linezolid | |
| rplC | 801339 | c.531T>C | synonymous_variant | 0.32 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 0.32 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 0.35 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 0.38 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 0.38 | linezolid | |
| rplC | 801402 | c.594T>C | synonymous_variant | 0.36 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 0.36 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 0.24 | linezolid | |
| rplC | 801426 | c.618C>G | synonymous_variant | 0.24 | linezolid | |
| rplC | 801427 | p.Met207Val | missense_variant | 0.23 | linezolid | |
| rplC | 801438 | c.630T>C | synonymous_variant | 0.29 | linezolid | |
| rplC | 801442 | p.Ile212Val | missense_variant | 0.29 | linezolid | |
| fbiC | 1303512 | c.582T>C | synonymous_variant | 0.21 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303521 | c.591C>T | synonymous_variant | 0.2 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303530 | c.600G>A | synonymous_variant | 0.21 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.21 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303539 | c.609G>C | synonymous_variant | 0.23 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 0.25 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 0.28 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303602 | c.672A>G | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303614 | c.684C>T | synonymous_variant | 0.3 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303617 | c.687C>G | synonymous_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303632 | c.702T>G | synonymous_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303641 | c.711C>T | synonymous_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303650 | c.720G>C | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303654 | c.724C>T | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303659 | c.729T>C | synonymous_variant | 0.34 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303661 | p.Val244Ala | missense_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303663 | c.733C>T | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303671 | c.741C>T | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303674 | c.744C>G | synonymous_variant | 0.36 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303681 | c.751T>C | synonymous_variant | 0.37 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303686 | c.756C>G | synonymous_variant | 0.38 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303695 | c.765T>C | synonymous_variant | 0.35 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 0.35 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 0.34 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303728 | c.798G>A | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303731 | c.801A>C | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303746 | c.816T>C | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303749 | c.819G>C | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303752 | c.822A>G | synonymous_variant | 0.33 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303755 | c.825T>C | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303761 | c.831T>C | synonymous_variant | 0.35 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303785 | c.855G>C | synonymous_variant | 0.34 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303789 | p.Ile287Val | missense_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303797 | c.867A>G | synonymous_variant | 0.3 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303818 | c.888C>G | synonymous_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303827 | c.897A>G | synonymous_variant | 0.27 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303836 | c.906G>C | synonymous_variant | 0.3 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303845 | c.915C>G | synonymous_variant | 0.28 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303846 | p.Phe306Val | missense_variant | 0.28 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303860 | c.930A>C | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303866 | p.Glu312Asp | missense_variant | 0.28 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303884 | c.954T>G | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303905 | c.975G>C | synonymous_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303914 | c.984C>G | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303920 | c.990C>T | synonymous_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.3 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303977 | c.1047C>A | synonymous_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.33 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303998 | c.1068T>G | synonymous_variant | 0.39 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.35 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304008 | c.1078_1080delTTGinsCTC | synonymous_variant | 0.36 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.34 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304031 | c.1101C>G | synonymous_variant | 0.35 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.36 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304040 | c.1110C>G | synonymous_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304049 | c.1119T>C | synonymous_variant | 0.3 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304050 | c.1120T>C | synonymous_variant | 0.3 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304058 | c.1128G>A | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304059 | c.1129C>T | synonymous_variant | 0.27 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.29 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304085 | c.1155C>T | synonymous_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304091 | p.Asp387Glu | missense_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 0.31 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304097 | c.1167G>C | synonymous_variant | 0.34 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304106 | c.1176G>C | synonymous_variant | 0.32 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.2 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.2 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.2 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304671 | p.Val581Thr | missense_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.2 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.22 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.22 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.22 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.22 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.21 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.23 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| Rv1258c | 1406341 | p.Tyr334His | missense_variant | 1.0 | streptomycin | Uncertain significance |
| pyrazinamide | ||||||
| isoniazid | Uncertain significance | |||||
| rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472045 | n.200T>A | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.36 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
| linezolid | ||||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
| linezolid | ||||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
| linezolid | ||||||
| rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
| linezolid | ||||||
| rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
| linezolid | ||||||
| rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
| linezolid | Not assoc w R | |||||
| rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
| linezolid | ||||||
| rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
| linezolid | ||||||
| rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
| linezolid | ||||||
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
| linezolid | ||||||
| rrl | 1474409 | n.756_766delACCCACACGCG | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
| linezolid | ||||||
| rrl | 1474427 | n.770A>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
| linezolid | ||||||
| rrl | 1474429 | n.772G>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
| linezolid | ||||||
| rrl | 1474431 | n.774_775delGCinsATTGGG | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
| linezolid | ||||||
| rrl | 1474435 | n.780_783delGAAT | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
| linezolid | ||||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
| linezolid | ||||||
| rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
| linezolid | ||||||
| rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
| linezolid | ||||||
| rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
| linezolid | ||||||
| rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
| linezolid | ||||||
| rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
| linezolid | ||||||
| rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
| linezolid | ||||||
| rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
| linezolid | ||||||
| rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
| linezolid | ||||||
| rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
| linezolid | ||||||
| rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
| linezolid | ||||||
| rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
| linezolid | ||||||
| rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
| linezolid | ||||||
| rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
| linezolid | ||||||
| rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
| linezolid | ||||||
| rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
| linezolid | ||||||
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
| linezolid | ||||||
| rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
| linezolid | ||||||
| rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
| linezolid | ||||||
| rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
| linezolid | ||||||
| rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
| linezolid | ||||||
| rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
| linezolid | ||||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
| linezolid | ||||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
| linezolid | ||||||
| rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
| linezolid | ||||||
| inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.26 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673568 | c.-634C>G | upstream_gene_variant | 0.28 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673574 | c.-628C>G | upstream_gene_variant | 0.26 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673580 | c.-622T>G | upstream_gene_variant | 0.26 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1673589 | c.-613A>G | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673591 | c.-611C>T | upstream_gene_variant | 0.23 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1673595 | c.-607A>C | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673596 | c.-606A>G | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673602 | c.-600C>T | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.23 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673615 | c.-587_-586delAAinsTG | upstream_gene_variant | 0.23 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673619 | c.-583T>C | upstream_gene_variant | 0.23 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673633 | c.-569G>A | upstream_gene_variant | 0.23 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673637 | c.-565C>G | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673641 | c.-561G>A | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673646 | c.-556T>C | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673657 | c.-545C>A | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673660 | c.-542C>A | upstream_gene_variant | 0.21 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 0.21 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 0.21 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673679 | c.-523T>C | upstream_gene_variant | 0.22 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1673685 | c.-517C>T | upstream_gene_variant | 0.24 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673710 | c.-492C>A | upstream_gene_variant | 0.22 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673716 | c.-486_-485delGCinsAA | upstream_gene_variant | 0.18 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673733 | c.-469G>C | upstream_gene_variant | 0.21 | isoniazid | |
| ethionamide | ||||||
| rpsA | 1833568 | c.27G>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833589 | c.48A>T | synonymous_variant | 0.29 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 0.32 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 0.34 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 0.32 | pyrazinamide | |
| rpsA | 1833721 | c.180A>G | synonymous_variant | 0.34 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 0.31 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 0.31 | pyrazinamide | |
| rpsA | 1833748 | c.207C>G | synonymous_variant | 0.32 | pyrazinamide | |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 0.36 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 0.34 | pyrazinamide | |
| rpsA | 1833940 | c.399C>G | synonymous_variant | 0.36 | pyrazinamide | |
| rpsA | 1833971 | c.430C>T | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 0.31 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 0.3 | pyrazinamide | |
| rpsA | 1834099 | c.558C>G | synonymous_variant | 0.3 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 0.3 | pyrazinamide | |
| rpsA | 1834105 | c.564C>G | synonymous_variant | 0.31 | pyrazinamide | |
| rpsA | 1834108 | c.567C>G | synonymous_variant | 0.31 | pyrazinamide | |
| rpsA | 1834123 | c.582C>G | synonymous_variant | 0.29 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 0.34 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1834154 | p.Asn205Gln | missense_variant | 0.33 | pyrazinamide | |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.33 | pyrazinamide | Uncertain significance |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 0.37 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834210 | c.669C>T | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834231 | c.690T>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834234 | c.693G>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834333 | c.792C>T | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834435 | c.894G>C | synonymous_variant | 0.5 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.5 | pyrazinamide | |
| rpsA | 1834513 | c.972C>G | synonymous_variant | 0.53 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 0.51 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 0.57 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.6 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.6 | pyrazinamide | |
| rpsA | 1834618 | c.1077G>C | synonymous_variant | 0.6 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.6 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.58 | pyrazinamide | |
| rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.57 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.52 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.49 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.49 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.44 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.44 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.42 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.37 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.29 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.29 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.39 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.33 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.34 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.33 | linezolid | |
| tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
| bacA | 2064936 | c.-208C>G | upstream_gene_variant | 0.3 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| bacA | 2064942 | c.-214G>A | upstream_gene_variant | 0.3 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| bacA | 2064948 | c.-220G>C | upstream_gene_variant | 0.29 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.35 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.36 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.36 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.36 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.33 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| ndh | 2101808 | p.Thr412Ser | missense_variant | 0.21 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101830 | p.Ile405Val | missense_variant | 0.2 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101837 | p.Ala402Val | missense_variant | 0.21 | isoniazid | Uncertain significance |
| delamanid | ||||||
| ethionamide | Uncertain significance | |||||
| ndh | 2101894 | c.1149T>G | synonymous_variant | 0.21 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101912 | c.1131G>C | synonymous_variant | 0.25 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101920 | c.1123A>C | synonymous_variant | 0.24 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101924 | c.1119T>G | synonymous_variant | 0.24 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101939 | c.1104A>G | synonymous_variant | 0.26 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101960 | c.1083A>G | synonymous_variant | 0.19 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101963 | c.1080G>A | synonymous_variant | 0.19 | isoniazid | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2101966 | c.1077T>G | synonymous_variant | 0.19 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| clofazimine | Not assoc w R | |||||
| kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.31 | isoniazid | |
| kasA | 2518076 | c.-39C>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 0.23 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 0.24 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 0.32 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 0.38 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 0.44 | isoniazid | |
| kasA | 2518639 | c.525G>C | synonymous_variant | 0.46 | isoniazid | |
| kasA | 2518657 | c.543G>C | synonymous_variant | 0.43 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 0.4 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 0.4 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518693 | c.579C>G | synonymous_variant | 0.35 | isoniazid | |
| kasA | 2518696 | c.582C>G | synonymous_variant | 0.35 | isoniazid | |
| kasA | 2518702 | c.588C>T | synonymous_variant | 0.34 | isoniazid | |
| kasA | 2518705 | c.591T>C | synonymous_variant | 0.32 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 0.3 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 0.3 | isoniazid | |
| kasA | 2518732 | c.618C>G | synonymous_variant | 0.32 | isoniazid | |
| kasA | 2518744 | c.630C>T | synonymous_variant | 0.32 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 0.32 | isoniazid | |
| kasA | 2518768 | c.654C>T | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518777 | c.663C>T | synonymous_variant | 0.42 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 0.42 | isoniazid | |
| kasA | 2518789 | c.675G>C | synonymous_variant | 0.41 | isoniazid | |
| kasA | 2518792 | c.678C>A | synonymous_variant | 0.41 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 0.41 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 0.49 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518879 | c.765A>G | synonymous_variant | 0.31 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 0.33 | isoniazid | |
| kasA | 2518898 | c.784T>C | synonymous_variant | 0.33 | isoniazid | |
| kasA | 2518906 | c.792A>G | synonymous_variant | 0.36 | isoniazid | |
| kasA | 2518910 | p.Leu266Met | missense_variant | 0.36 | isoniazid | |
| kasA | 2518921 | c.807T>C | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518936 | c.822C>G | synonymous_variant | 0.39 | isoniazid | |
| kasA | 2518939 | c.825T>C | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518942 | c.828T>C | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518951 | c.837G>C | synonymous_variant | 0.42 | isoniazid | |
| kasA | 2518954 | c.840C>G | synonymous_variant | 0.41 | isoniazid | |
| kasA | 2518963 | c.849T>C | synonymous_variant | 0.44 | isoniazid | |
| kasA | 2518969 | c.855T>G | synonymous_variant | 0.36 | isoniazid | |
| ahpC | 2726486 | c.294A>G | synonymous_variant | 0.21 | isoniazid | |
| ahpC | 2726493 | p.Asn101Glu | missense_variant | 0.23 | isoniazid | |
| ahpC | 2726506 | p.Thr105Lys | missense_variant | 0.27 | isoniazid | Uncertain significance |
| ahpC | 2726508 | c.316_318delTTAinsCTG | synonymous_variant | 0.25 | isoniazid | |
| ahpC | 2726528 | c.336C>G | synonymous_variant | 0.29 | isoniazid | |
| ahpC | 2726540 | c.348C>G | synonymous_variant | 0.27 | isoniazid | |
| ahpC | 2726543 | c.351A>G | synonymous_variant | 0.28 | isoniazid | |
| ahpC | 2726546 | c.354C>G | synonymous_variant | 0.26 | isoniazid | |
| ahpC | 2726551 | p.Gln120Leu | missense_variant | 0.26 | isoniazid | |
| ahpC | 2726556 | p.Ala122Thr | missense_variant | 0.25 | isoniazid | Uncertain significance |
| ahpC | 2726564 | c.372C>G | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726579 | c.387T>C | synonymous_variant | 0.24 | isoniazid | |
| ahpC | 2726593 | p.Val134Ala | missense_variant | 0.2 | isoniazid | |
| ahpC | 2726600 | c.408T>C | synonymous_variant | 0.2 | isoniazid | |
| ahpC | 2726601 | p.Ile137Leu | missense_variant | 0.2 | isoniazid | |
| Rv2477c | 2782695 | c.1348A>C | synonymous_variant | 0.2 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782711 | c.1332C>G | synonymous_variant | 0.21 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782714 | c.1329A>C | synonymous_variant | 0.21 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782720 | c.1323T>C | synonymous_variant | 0.22 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782729 | c.1314A>G | synonymous_variant | 0.24 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782732 | c.1311A>G | synonymous_variant | 0.22 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782741 | c.1302G>A | synonymous_variant | 0.18 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782750 | c.1293T>C | synonymous_variant | 0.2 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782759 | c.1284A>G | synonymous_variant | 0.23 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782828 | c.1215T>C | synonymous_variant | 0.38 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782841 | p.Thr401Asn | missense_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782847 | p.Arg399Lys | missense_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782852 | c.1191T>C | synonymous_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782861 | c.1182T>G | synonymous_variant | 0.44 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782869 | p.Ala392Thr | missense_variant | 0.48 | kanamycin | Uncertain significance |
| levofloxacin | Uncertain significance | |||||
| moxifloxacin | Uncertain significance | |||||
| streptomycin | ||||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 0.55 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 0.52 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 0.44 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.44 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.52 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.54 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.44 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.43 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.43 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.46 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.48 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.53 | kanamycin | Uncertain significance |
| levofloxacin | Uncertain significance | |||||
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783044 | c.999G>A | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783051 | p.Tyr331Phe | missense_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.55 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783062 | c.981C>T | synonymous_variant | 0.55 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.55 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.59 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.55 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.54 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.51 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.52 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.57 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.57 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | ||||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.58 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.59 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783185 | c.858G>A | synonymous_variant | 0.58 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.61 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.57 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.58 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783275 | c.768C>G | synonymous_variant | 0.59 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | c.765A>G | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783314 | c.729C>G | synonymous_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783317 | c.726G>C | synonymous_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783335 | c.708C>G | synonymous_variant | 0.44 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783344 | c.699C>G | synonymous_variant | 0.43 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.39 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.41 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 0.33 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 0.33 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>C | synonymous_variant | 0.3 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | p.Pro206Ala | missense_variant | 0.3 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| amikacin | ||||||
| Rv2477c | 2783428 | c.615C>T | synonymous_variant | 0.31 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | ||||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783431 | c.610_612delAGCinsTCG | synonymous_variant | 0.32 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783437 | c.606G>C | synonymous_variant | 0.31 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.33 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.4 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783464 | c.579A>G | synonymous_variant | 0.43 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.43 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 0.47 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783497 | c.544_546delTTGinsCTC | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.53 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.55 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.52 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783521 | c.522G>C | synonymous_variant | 0.52 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.47 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.39 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.38 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.38 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.38 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783557 | c.486T>C | synonymous_variant | 0.38 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.36 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.37 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.39 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.43 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.46 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783662 | c.381G>A | synonymous_variant | 0.49 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.53 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.52 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.52 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.51 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.49 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.49 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.55 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.51 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.47 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.47 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.48 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.5 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.49 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.42 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.41 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.41 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.4 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.42 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.39 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.39 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.37 | kanamycin | Not assoc w R - Interim |
| levofloxacin | ||||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.36 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.41 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.37 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2752c | 3064876 | p.Ser439Phe | missense_variant | 0.86 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| Rv2752c | 3064914 | c.1278T>G | synonymous_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064926 | c.1264_1266delTTGinsCTC | synonymous_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064932 | c.1260T>C | synonymous_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064935 | c.1257A>G | synonymous_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064941 | p.Gln417Glu | missense_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064947 | c.1245A>G | synonymous_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064956 | p.Ser412Arg | missense_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| Rv2752c | 3064962 | c.1230C>G | synonymous_variant | 0.35 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064973 | p.Ala407Ser | missense_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064995 | c.1197C>G | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064998 | c.1194A>G | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065007 | c.1185G>C | synonymous_variant | 0.35 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065013 | c.1179G>C | synonymous_variant | 0.41 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065018 | p.Asn392His | missense_variant | 0.41 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065022 | c.1170G>C | synonymous_variant | 0.41 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065028 | p.Val388Ile | missense_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065040 | c.1152C>G | synonymous_variant | 0.43 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065048 | c.1144C>T | synonymous_variant | 0.52 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065052 | c.1140G>A | synonymous_variant | 0.52 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065055 | c.1137T>C | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065079 | c.1113T>C | synonymous_variant | 0.59 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065082 | c.1110G>T | synonymous_variant | 0.59 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065085 | c.1105_1107delAGGinsCGC | synonymous_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065109 | c.1081_1083delAGAinsCGC | synonymous_variant | 0.58 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065115 | c.1077C>A | synonymous_variant | 0.56 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065126 | p.Ser356Ala | missense_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065127 | c.1065G>C | synonymous_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065130 | p.Ala354Glu | missense_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 0.4 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065151 | c.1041G>C | synonymous_variant | 0.43 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065183 | p.Ser337Ala | missense_variant | 0.43 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065186 | c.1006T>C | synonymous_variant | 0.39 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065190 | p.Ile334Val | missense_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065196 | c.996T>C | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065202 | c.990T>G | synonymous_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065205 | c.987T>C | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065210 | c.982T>C | synonymous_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065232 | c.960T>C | synonymous_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065241 | c.951A>G | synonymous_variant | 0.26 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| thyX | 3067349 | c.597G>C | synonymous_variant | 0.5 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 0.48 | para-aminosalicylic_acid | |
| thyX | 3067367 | c.579G>C | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
| thyX | 3067388 | c.558C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
| thyX | 3067391 | c.555G>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
| thyX | 3067445 | c.501C>G | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
| thyX | 3067457 | c.489C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
| thyX | 3067462 | c.484C>T | synonymous_variant | 0.45 | para-aminosalicylic_acid | |
| thyX | 3067465 | p.Ile161Val | missense_variant | 0.43 | para-aminosalicylic_acid | |
| thyX | 3067475 | c.471A>G | synonymous_variant | 0.43 | para-aminosalicylic_acid | |
| thyX | 3067490 | c.456C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
| thyX | 3067493 | c.453A>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
| thyX | 3067515 | p.Ser144Thr | missense_variant | 0.41 | para-aminosalicylic_acid | |
| thyX | 3067530 | p.Ala139Ser | missense_variant | 0.44 | para-aminosalicylic_acid | |
| thyX | 3067545 | p.Glu134Ala | missense_variant | 0.46 | para-aminosalicylic_acid | |
| thyX | 3067549 | p.Thr133Ala | missense_variant | 0.44 | para-aminosalicylic_acid | |
| thyX | 3067556 | p.His130Gln | missense_variant | 0.43 | para-aminosalicylic_acid | |
| thyX | 3067559 | c.387C>G | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
| thyX | 3067565 | p.Asp127Glu | missense_variant | 0.41 | para-aminosalicylic_acid | |
| thyX | 3067570 | p.Ala126Pro | missense_variant | 0.43 | para-aminosalicylic_acid | |
| thyX | 3067577 | c.369G>A | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
| thyX | 3067583 | c.363C>G | synonymous_variant | 0.48 | para-aminosalicylic_acid | |
| thyX | 3067601 | p.Arg115His | missense_variant | 0.43 | para-aminosalicylic_acid | |
| thyX | 3067611 | p.Lys112Thr | missense_variant | 0.43 | para-aminosalicylic_acid | |
| thyX | 3067772 | c.174C>G | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 0.34 | para-aminosalicylic_acid | |
| thyX | 3067793 | c.153T>C | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
| thyX | 3067799 | c.147G>A | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
| thyX | 3067802 | c.144C>G | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
| thyA | 3073791 | c.681T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyA | 3073794 | c.678A>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
| thyA | 3073812 | c.660C>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
| thyA | 3073815 | c.657G>A | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
| thyA | 3073824 | c.648A>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyA | 3073839 | c.633T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
| thyA | 3073860 | c.612C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
| thyA | 3073863 | c.609T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
| thyA | 3073866 | c.606C>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
| thyA | 3073872 | p.Ile200Val | missense_variant | 0.27 | para-aminosalicylic_acid | |
| thyA | 3073917 | c.555C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
| thyA | 3073920 | c.552C>G | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
| thyA | 3074010 | c.462C>G | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
| thyA | 3074028 | c.444G>C | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
| thyA | 3074031 | c.441T>C | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
| thyA | 3074037 | c.435C>G | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
| thyA | 3074053 | p.Arg140Gln | missense_variant | 0.28 | para-aminosalicylic_acid | |
| thyA | 3074055 | p.Glu139Pro | missense_variant | 0.28 | para-aminosalicylic_acid | |
| thyA | 3074061 | c.411A>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
| thyA | 3074079 | c.393G>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
| thyA | 3074097 | c.375C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
| thyA | 3074100 | p.Asp124Asn | missense_variant | 0.23 | para-aminosalicylic_acid | |
| thyA | 3074106 | c.366T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
| thyA | 3074127 | c.345G>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
| thyA | 3074130 | c.342G>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
| thyA | 3074154 | c.318T>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
| thyA | 3074175 | c.297A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
| thyA | 3074181 | c.291A>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
| thyA | 3074187 | c.285T>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
| thyA | 3074205 | p.Glu89Asp | missense_variant | 0.3 | para-aminosalicylic_acid | |
| thyA | 3074214 | c.258T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
| thyA | 3074244 | c.228A>G | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
| ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
| lpqB | 3623531 | c.1380T>C | synonymous_variant | 0.22 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623549 | c.1362C>G | synonymous_variant | 0.21 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623555 | p.Gly452Ser | missense_variant | 0.21 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623561 | c.1350T>C | synonymous_variant | 0.19 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623575 | p.Leu446Phe | missense_variant | 0.18 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| lpqB | 3623580 | p.Asn444Thr | missense_variant | 0.21 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623587 | p.Ala442Pro | missense_variant | 0.21 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623597 | c.1314C>G | synonymous_variant | 0.21 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623601 | p.Ser437Thr | missense_variant | 0.21 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623612 | p.Thr433Val | missense_variant | 0.22 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623630 | c.1281G>C | synonymous_variant | 0.23 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624107 | c.804C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624116 | c.795A>G | synonymous_variant | 0.28 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624119 | c.792C>G | synonymous_variant | 0.28 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624124 | p.Leu263Val | missense_variant | 0.27 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624125 | c.786A>G | synonymous_variant | 0.28 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624143 | c.768T>C | synonymous_variant | 0.26 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
| bedaquiline | Uncertain significance | |||||
| lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.32 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 0.32 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625206 | p.Ser470Ala | missense_variant | 0.32 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625225 | c.-315G>C | upstream_gene_variant | 0.33 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.3 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.32 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625549 | c.-639G>A | upstream_gene_variant | 0.37 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.42 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.38 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.44 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.45 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.44 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.43 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.43 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625636 | c.978C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.48 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.5 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.54 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.5 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.5 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625705 | c.909C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.54 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.51 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.45 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625750 | c.864G>A | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.42 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625774 | c.840G>A | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625797 | p.Val273Met | missense_variant | 0.4 | rifampicin | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625807 | c.807C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.39 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.38 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626124 | p.Ala164Ser | missense_variant | 0.22 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626125 | c.489C>G | synonymous_variant | 0.25 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626155 | p.Ala153Ser | missense_variant | 0.27 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626158 | c.456C>T | synonymous_variant | 0.26 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626161 | c.453C>A | synonymous_variant | 0.26 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626170 | c.444T>C | synonymous_variant | 0.32 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626179 | c.435A>T | synonymous_variant | 0.31 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626185 | c.429T>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626188 | p.Ser142Thr | missense_variant | 0.31 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626191 | c.423C>G | synonymous_variant | 0.32 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626194 | c.420T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626203 | c.411G>A | synonymous_variant | 0.35 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626206 | c.408T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626209 | c.405T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626230 | c.384T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626236 | c.378G>C | synonymous_variant | 0.27 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626239 | c.375T>C | synonymous_variant | 0.26 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626245 | p.Leu123Met | missense_variant | 0.25 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626248 | c.366C>G | synonymous_variant | 0.23 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626251 | c.363T>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626254 | c.360G>C | synonymous_variant | 0.23 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626257 | c.357G>C | synonymous_variant | 0.24 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626260 | c.354T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626263 | p.Pro117Gln | missense_variant | 0.24 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626272 | c.342A>G | synonymous_variant | 0.24 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626275 | c.339G>C | synonymous_variant | 0.24 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626284 | c.330T>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626293 | c.321G>C | synonymous_variant | 0.24 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626296 | c.318T>G | synonymous_variant | 0.25 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626308 | c.306T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626317 | c.297A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626325 | p.Thr97Ala | missense_variant | 0.23 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626332 | c.282T>C | synonymous_variant | 0.22 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626338 | c.276C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.19 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.2 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.22 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.22 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.23 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.27 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.2 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.22 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 0.26 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.26 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626939 | c.411A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.3 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.32 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.42 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.44 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.39 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.39 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.35 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627071 | c.279G>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.42 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.38 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.43 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.33 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.36 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.35 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.35 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627188 | c.162A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.3 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627221 | c.129C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627227 | c.123T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.29 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.3 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627242 | c.108C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.28 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.27 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.24 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.23 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.23 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.22 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627299 | c.51G>A | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| fbiB | 3640899 | c.-636G>C | upstream_gene_variant | 0.19 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| rpoA | 3877494 | p.Glu338Asp | missense_variant | 0.24 | rifampicin | Uncertain significance |
| rpoA | 3877503 | c.1005G>C | synonymous_variant | 0.27 | rifampicin | |
| rpoA | 3877507 | p.Gly334Ala | missense_variant | 0.25 | rifampicin | |
| rpoA | 3877515 | c.993G>C | synonymous_variant | 0.26 | rifampicin | |
| rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.27 | rifampicin | |
| rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.26 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 0.31 | rifampicin | |
| rpoA | 3877617 | c.891G>C | synonymous_variant | 0.3 | rifampicin | |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 0.34 | rifampicin | |
| rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.34 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 0.29 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 0.35 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877748 | c.760C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877791 | c.717C>G | synonymous_variant | 0.31 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 0.54 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 0.53 | rifampicin | |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 0.54 | rifampicin | |
| rpoA | 3877878 | c.630G>C | synonymous_variant | 0.54 | rifampicin | |
| rpoA | 3877890 | c.618C>T | synonymous_variant | 0.52 | rifampicin | |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 0.52 | rifampicin | |
| rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.52 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.49 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877923 | c.585C>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 0.55 | rifampicin | |
| rpoA | 3877962 | c.546G>C | synonymous_variant | 0.57 | rifampicin | |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 0.59 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 0.63 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 0.63 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 0.63 | rifampicin | |
| rpoA | 3878040 | c.468T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 0.61 | rifampicin | |
| rpoA | 3878058 | c.450G>T | synonymous_variant | 0.63 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 0.58 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 0.59 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 0.61 | rifampicin | |
| rpoA | 3878076 | c.432C>T | synonymous_variant | 0.6 | rifampicin | |
| rpoA | 3878094 | c.414C>G | synonymous_variant | 0.5 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 0.47 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 0.48 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 0.39 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 0.41 | rifampicin | |
| rpoA | 3878141 | p.Met123Leu | missense_variant | 0.38 | rifampicin | Uncertain significance |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.4 | rifampicin | Uncertain significance |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 0.4 | rifampicin | |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878172 | c.336G>C | synonymous_variant | 0.42 | rifampicin | |
| rpoA | 3878187 | c.321C>A | synonymous_variant | 0.4 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878226 | c.282C>G | synonymous_variant | 0.55 | rifampicin | |
| rpoA | 3878232 | c.276G>C | synonymous_variant | 0.56 | rifampicin | |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 0.59 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.6 | rifampicin | |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 0.56 | rifampicin | |
| rpoA | 3878310 | c.198G>C | synonymous_variant | 0.56 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 0.63 | rifampicin | |
| rpoA | 3878352 | c.156C>G | synonymous_variant | 0.63 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 0.64 | rifampicin | |
| rpoA | 3878367 | c.141C>G | synonymous_variant | 0.64 | rifampicin | |
| rpoA | 3878376 | c.132G>C | synonymous_variant | 0.66 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 0.62 | rifampicin | |
| rpoA | 3878388 | c.120C>G | synonymous_variant | 0.66 | rifampicin | |
| rpoA | 3878391 | c.117T>C | synonymous_variant | 0.64 | rifampicin | |
| rpoA | 3878415 | c.93C>T | synonymous_variant | 0.61 | rifampicin | |
| rpoA | 3878424 | c.84G>C | synonymous_variant | 0.61 | rifampicin | |
| rpoA | 3878436 | c.72A>G | synonymous_variant | 0.6 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 0.59 | rifampicin | |
| rpoA | 3878454 | c.54A>C | synonymous_variant | 0.53 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.54 | rifampicin | |
| rpoA | 3878478 | c.30C>G | synonymous_variant | 0.54 | rifampicin | |
| rpoA | 3878484 | c.24C>A | synonymous_variant | 0.52 | rifampicin | |
| rpoA | 3878490 | c.18C>A | synonymous_variant | 0.48 | rifampicin | |
| rpoA | 3878496 | c.12A>T | synonymous_variant | 0.48 | rifampicin | |
| rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.47 | rifampicin | |
| rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.5 | rifampicin | |
| rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.5 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.5 | rifampicin | |
| rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.5 | rifampicin | Uncertain significance |
| rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.5 | rifampicin | |
| rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.45 | rifampicin | |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.48 | rifampicin | |
| rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.54 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.5 | rifampicin | Uncertain significance |
| rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.54 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.54 | rifampicin | |
| rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.56 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.56 | rifampicin | |
| rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.52 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.68 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.66 | rifampicin | Uncertain significance |
| rpoA | 3878881 | c.-374C>T | upstream_gene_variant | 0.64 | rifampicin | |
| rpoA | 3878890 | c.-383C>G | upstream_gene_variant | 0.59 | rifampicin | |
| rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.52 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.52 | rifampicin | Uncertain significance |
| rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.48 | rifampicin | Uncertain significance |
| rpoA | 3878932 | c.-425G>A | upstream_gene_variant | 0.5 | rifampicin | |
| rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 0.48 | rifampicin | |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.53 | rifampicin | Uncertain significance |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.57 | rifampicin | Uncertain significance |
| rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.55 | rifampicin | Uncertain significance |
| rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.55 | rifampicin | |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.53 | rifampicin | Uncertain significance |
| rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.54 | rifampicin | |
| rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.54 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.56 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.56 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.56 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.57 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.59 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.44 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.44 | rifampicin | |
| rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.45 | rifampicin | |
| rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.39 | rifampicin | |
| rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 0.31 | rifampicin | |
| rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.32 | rifampicin | |
| rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 0.33 | rifampicin | |
| rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 0.35 | rifampicin | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038407 | c.2298G>C | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038434 | c.2271G>A | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.28 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.3 | pyrazinamide | |
| clpC1 | 4038460 | p.Leu749Met | missense_variant | 0.27 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4038821 | c.1884G>A | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039229 | c.1476C>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.37 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039454 | c.1251A>G | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039480 | c.1225C>A | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>G | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.34 | pyrazinamide | Uncertain significance |
| clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4039625 | c.1080G>A | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.32 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.32 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040278 | p.Ser143Thr | missense_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4040444 | c.261C>T | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040477 | c.228G>C | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4040501 | c.204C>T | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044812 | c.-531A>C | upstream_gene_variant | 0.25 | pyrazinamide | |
| panD | 4044818 | c.-538_-537delCGinsAC | upstream_gene_variant | 0.24 | pyrazinamide | |
| panD | 4044823 | c.-542G>C | upstream_gene_variant | 0.24 | pyrazinamide | |
| panD | 4044844 | c.-563T>C | upstream_gene_variant | 0.24 | pyrazinamide | |
| panD | 4044848 | c.-567T>G | upstream_gene_variant | 0.25 | pyrazinamide | |
| panD | 4044854 | c.-573A>G | upstream_gene_variant | 0.23 | pyrazinamide | |
| panD | 4044860 | c.-579C>G | upstream_gene_variant | 0.21 | pyrazinamide | |
| panD | 4044872 | c.-591C>G | upstream_gene_variant | 0.21 | pyrazinamide | |
| panD | 4044895 | c.-614A>G | upstream_gene_variant | 0.19 | pyrazinamide | |
| panD | 4044909 | c.-628C>T | upstream_gene_variant | 0.17 | pyrazinamide | |
| panD | 4044926 | c.-645C>A | upstream_gene_variant | 0.17 | pyrazinamide | |
| panD | 4044936 | c.-655A>T | upstream_gene_variant | 0.16 | pyrazinamide | |
| panD | 4044954 | c.-674_-673delCCinsAT | upstream_gene_variant | 0.2 | pyrazinamide | |
| panD | 4044959 | c.-678C>G | upstream_gene_variant | 0.2 | pyrazinamide | |
| panD | 4044983 | c.-702G>T | upstream_gene_variant | 0.18 | pyrazinamide | |
| glpK | 4138460 | c.1296C>T | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138472 | c.1284G>T | synonymous_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138478 | c.1278T>C | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138481 | c.1275G>C | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138490 | c.1266G>T | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138495 | p.Gln421Glu | missense_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138496 | c.1260G>T | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138502 | c.1254T>G | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138511 | c.1245C>T | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138514 | c.1242A>G | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138517 | p.Glu413Ala | missense_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138523 | c.1233C>G | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138529 | c.1227G>A | synonymous_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138535 | c.1221T>C | synonymous_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138565 | c.1191G>C | synonymous_variant | 0.46 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138580 | c.1176C>T | synonymous_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138598 | c.1158G>A | synonymous_variant | 0.45 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138601 | c.1155G>C | synonymous_variant | 0.45 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138604 | c.1150_1152delTTGinsCTA | synonymous_variant | 0.45 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138610 | c.1146C>G | synonymous_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138622 | c.1134C>G | synonymous_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138625 | c.1131G>C | synonymous_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138628 | c.1128T>C | synonymous_variant | 0.43 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138634 | c.1122G>A | synonymous_variant | 0.46 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138643 | c.1113A>C | synonymous_variant | 0.41 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138646 | c.1110G>C | synonymous_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138654 | c.1102C>T | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138670 | c.1086G>C | synonymous_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138679 | p.Met359Val | missense_variant | 0.41 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138695 | p.Pro354Asp | missense_variant | 0.41 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 0.37 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138721 | c.1035G>A | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138724 | c.1032A>G | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138730 | c.1026C>G | synonymous_variant | 0.34 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138763 | c.993G>A | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139408 | c.348T>C | synonymous_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139417 | c.339A>C | synonymous_variant | 0.3 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139420 | c.336T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4139537 | c.219G>C | synonymous_variant | 0.41 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139541 | p.Ile72Thr | missense_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139545 | c.211T>C | synonymous_variant | 0.38 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139552 | p.Ala68Ser | missense_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139561 | c.195G>A | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139581 | p.Asn59Asp | missense_variant | 0.35 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| embC | 4239298 | c.-565C>T | upstream_gene_variant | 0.97 | ethambutol | Not assoc w R |
| embC | 4240780 | c.918T>C | synonymous_variant | 0.26 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 0.26 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 0.26 | ethambutol | |
| embC | 4240819 | c.957A>G | synonymous_variant | 0.25 | ethambutol | |
| embC | 4240828 | c.966G>C | synonymous_variant | 0.26 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 0.26 | ethambutol | |
| embC | 4240867 | c.1005T>C | synonymous_variant | 0.26 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 0.21 | ethambutol | |
| embC | 4241023 | c.1161T>G | synonymous_variant | 0.19 | ethambutol | |
| embC | 4241032 | c.1170G>C | synonymous_variant | 0.18 | ethambutol | |
| embC | 4241047 | c.1185C>G | synonymous_variant | 0.19 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 0.18 | ethambutol | |
| embC | 4241053 | c.1191G>C | synonymous_variant | 0.18 | ethambutol | |
| embC | 4241089 | c.1227C>G | synonymous_variant | 0.21 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 0.21 | ethambutol | |
| embC | 4241107 | c.1245G>C | synonymous_variant | 0.2 | ethambutol | |
| embC | 4241203 | c.1341T>C | synonymous_variant | 0.22 | ethambutol | |
| embC | 4241206 | c.1344G>C | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
| embC | 4241218 | c.1356G>C | synonymous_variant | 0.26 | ethambutol | |
| embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embA | 4242742 | c.-491C>G | upstream_gene_variant | 0.28 | ethambutol | |
| embA | 4242748 | c.-485A>G | upstream_gene_variant | 0.38 | ethambutol | |
| embA | 4242754 | c.-479G>C | upstream_gene_variant | 0.36 | ethambutol | |
| embC | 4242764 | p.Val968Leu | missense_variant | 0.35 | ethambutol | |
| embC | 4242779 | p.Asn973Asp | missense_variant | 0.35 | ethambutol | |
| embC | 4242791 | p.Ala977Ser | missense_variant | 0.29 | ethambutol | |
| embA | 4242796 | c.-437G>C | upstream_gene_variant | 0.29 | ethambutol | |
| embA | 4242799 | c.-434T>C | upstream_gene_variant | 0.27 | ethambutol | |
| embC | 4242803 | p.Val981Leu | missense_variant | 0.74 | ethambutol | Not assoc w R |
| embA | 4242820 | c.-413G>C | upstream_gene_variant | 0.26 | ethambutol | |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.26 | ethambutol | |
| embA | 4242832 | c.-401A>C | upstream_gene_variant | 0.29 | ethambutol | |
| embA | 4242838 | c.-395C>G | upstream_gene_variant | 0.27 | ethambutol | |
| embC | 4242841 | c.2979C>T | synonymous_variant | 0.28 | ethambutol | Not assoc w R - Interim |
| embA | 4242844 | c.-389A>G | upstream_gene_variant | 0.28 | ethambutol | |
| embA | 4242847 | c.-386C>A | upstream_gene_variant | 0.28 | ethambutol | |
| embA | 4242859 | c.-374C>T | upstream_gene_variant | 0.24 | ethambutol | |
| embA | 4242862 | c.-371A>G | upstream_gene_variant | 0.24 | ethambutol | |
| embC | 4242863 | p.Tyr1001Asn | missense_variant | 0.23 | ethambutol | |
| embC | 4242883 | c.3021C>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
| embA | 4245083 | c.1851A>C | synonymous_variant | 0.31 | ethambutol | |
| embA | 4245101 | c.1869G>C | synonymous_variant | 0.31 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 0.29 | ethambutol | |
| embA | 4245146 | c.1914G>A | synonymous_variant | 0.27 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 0.29 | ethambutol | |
| embA | 4245153 | p.Ile641Val | missense_variant | 0.32 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 0.38 | ethambutol | |
| embA | 4245189 | c.1957C>T | synonymous_variant | 0.36 | ethambutol | |
| embA | 4245198 | p.Leu656Ile | missense_variant | 0.36 | ethambutol | |
| embA | 4245207 | c.1975T>C | synonymous_variant | 0.38 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 0.37 | ethambutol | |
| embA | 4245222 | p.Tyr664Gln | missense_variant | 0.36 | ethambutol | |
| embA | 4245248 | c.2016G>C | synonymous_variant | 0.45 | ethambutol | |
| embA | 4245257 | c.2025A>G | synonymous_variant | 0.45 | ethambutol | |
| embA | 4245263 | c.2031A>G | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
| embA | 4245282 | p.Ile684Val | missense_variant | 0.29 | ethambutol | |
| embA | 4245285 | c.2053T>C | synonymous_variant | 0.29 | ethambutol | |
| embA | 4245290 | c.2058C>G | synonymous_variant | 0.3 | ethambutol | |
| embB | 4247413 | c.900C>T | synonymous_variant | 0.24 | ethambutol | |
| embB | 4247425 | c.912G>C | synonymous_variant | 0.25 | ethambutol | |
| embB | 4247434 | c.921C>G | synonymous_variant | 0.3 | ethambutol | |
| embB | 4247437 | c.924A>G | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
| embB | 4247440 | c.927C>G | synonymous_variant | 0.3 | ethambutol | |
| embB | 4247446 | c.933C>T | synonymous_variant | 0.3 | ethambutol | |
| embB | 4247464 | c.951C>G | synonymous_variant | 0.33 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 0.34 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 0.3 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 0.29 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 0.25 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 0.27 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 0.23 | ethambutol | |
| embB | 4247566 | c.1053C>A | synonymous_variant | 0.25 | ethambutol | |
| embB | 4247572 | c.1059A>G | synonymous_variant | 0.25 | ethambutol | |
| embB | 4247579 | p.Ala356Phe | missense_variant | 0.23 | ethambutol | |
| embB | 4247587 | c.1074G>A | synonymous_variant | 0.23 | ethambutol | |
| embB | 4247603 | c.1090C>T | synonymous_variant | 0.28 | ethambutol | |
| embB | 4247611 | c.1098G>T | synonymous_variant | 0.28 | ethambutol | Not assoc w R - Interim |
| embB | 4247614 | c.1101T>C | synonymous_variant | 0.28 | ethambutol | Not assoc w R - Interim |
| embB | 4247629 | c.1116C>G | synonymous_variant | 0.27 | ethambutol | |
| embB | 4247632 | c.1119C>G | synonymous_variant | 0.25 | ethambutol | |
| embB | 4247638 | c.1125G>C | synonymous_variant | 0.22 | ethambutol | |
| embB | 4247646 | p.Glu378Ala | missense_variant | 0.2 | ethambutol | Not assoc w R |
| embB | 4247656 | c.1143A>G | synonymous_variant | 0.2 | ethambutol | |
| embB | 4247659 | c.1146C>G | synonymous_variant | 0.2 | ethambutol | |
| embB | 4247662 | c.1149C>G | synonymous_variant | 0.2 | ethambutol | |
| embB | 4247683 | c.1170C>G | synonymous_variant | 0.23 | ethambutol | |
| embB | 4247692 | c.1179C>G | synonymous_variant | 0.2 | ethambutol | |
| embB | 4247746 | c.1233C>T | synonymous_variant | 0.17 | ethambutol | |
| embB | 4247761 | c.1248T>C | synonymous_variant | 0.22 | ethambutol | |
| embB | 4248035 | p.Val508Ile | missense_variant | 0.31 | ethambutol | |
| embB | 4248040 | c.1527C>G | synonymous_variant | 0.31 | ethambutol | |
| embB | 4248041 | p.Ala510Thr | missense_variant | 0.31 | ethambutol | Uncertain significance |
| embB | 4248044 | p.Lys511Ala | missense_variant | 0.31 | ethambutol | |
| embB | 4248070 | c.1557T>C | synonymous_variant | 0.37 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 0.4 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 0.4 | ethambutol | |
| embB | 4248130 | c.1617G>C | synonymous_variant | 0.33 | ethambutol | |
| embB | 4248133 | c.1620C>G | synonymous_variant | 0.33 | ethambutol | |
| embB | 4248139 | c.1626C>G | synonymous_variant | 0.33 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 0.33 | ethambutol | |
| embB | 4248143 | c.1630T>C | synonymous_variant | 0.33 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
| embB | 4248199 | c.1686A>G | synonymous_variant | 0.33 | ethambutol | |
| embB | 4248200 | p.Ile563Val | missense_variant | 0.33 | ethambutol | |
| embB | 4248205 | c.1692C>G | synonymous_variant | 0.3 | ethambutol | |
| embB | 4248206 | p.Ser565Gly | missense_variant | 0.3 | ethambutol | Uncertain significance |
| embB | 4248220 | c.1707A>C | synonymous_variant | 0.3 | ethambutol | |
| embB | 4248304 | c.1791G>C | synonymous_variant | 0.21 | ethambutol | |
| embB | 4249498 | c.2985G>C | synonymous_variant | 0.3 | ethambutol | |
| embB | 4249521 | p.Ala1003Val | missense_variant | 0.29 | ethambutol | |
| embB | 4249525 | c.3012T>C | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
| embB | 4249529 | p.Ile1006Val | missense_variant | 0.3 | ethambutol | |
| embB | 4249532 | p.Ala1007Thr | missense_variant | 0.3 | ethambutol | Uncertain significance |
| embB | 4249537 | c.3024A>G | synonymous_variant | 0.3 | ethambutol | |
| embB | 4249543 | c.3030G>C | synonymous_variant | 0.29 | ethambutol | |
| embB | 4249546 | c.3033G>A | synonymous_variant | 0.29 | ethambutol | |
| embB | 4249558 | c.3045A>C | synonymous_variant | 0.29 | ethambutol | |
| embB | 4249568 | p.Ser1019Thr | missense_variant | 0.29 | ethambutol | |
| embB | 4249573 | c.3060T>C | synonymous_variant | 0.29 | ethambutol | |
| embB | 4249580 | p.Leu1023Met | missense_variant | 0.29 | ethambutol | |
| aftB | 4268225 | c.612G>C | synonymous_variant | 0.27 | ethambutol | |
| aftB | 4268236 | p.Leu201Met | missense_variant | 0.26 | ethambutol | |
| ubiA | 4269075 | p.Ile253Val | missense_variant | 0.38 | ethambutol | |
| aftB | 4269081 | c.-245G>C | upstream_gene_variant | 0.33 | ethambutol | |
| aftB | 4269084 | c.-248G>C | upstream_gene_variant | 0.33 | ethambutol | |
| ubiA | 4269102 | c.731_732delGCinsCCATTCG | frameshift_variant&missense_variant | 0.3 | ethambutol | |
| ubiA | 4269105 | c.724_728delGGCTA | frameshift_variant | 0.3 | ethambutol | |
| aftB | 4269123 | c.-287T>G | upstream_gene_variant | 0.3 | ethambutol | |
| ubiA | 4269131 | c.703C>T | synonymous_variant | 0.28 | ethambutol | Not assoc w R - Interim |
| aftB | 4269132 | c.-296G>C | upstream_gene_variant | 0.28 | ethambutol | |
| aftB | 4269138 | c.-302C>T | upstream_gene_variant | 0.27 | ethambutol | |
| ubiA | 4269141 | p.Leu231Val | missense_variant | 0.27 | ethambutol | |
| ubiA | 4269144 | c.690C>G | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
| aftB | 4269159 | c.-323G>C | upstream_gene_variant | 0.29 | ethambutol | |
| ubiA | 4269164 | p.Leu224Met | missense_variant | 0.29 | ethambutol | |
| aftB | 4269165 | c.-329G>C | upstream_gene_variant | 0.27 | ethambutol | |
| aftB | 4269179 | c.-343C>A | upstream_gene_variant | 0.25 | ethambutol | |
| aftB | 4269183 | c.-347T>C | upstream_gene_variant | 0.27 | ethambutol | |
| aftB | 4269186 | c.-350C>G | upstream_gene_variant | 0.27 | ethambutol | |
| aftB | 4269201 | c.-365A>G | upstream_gene_variant | 0.32 | ethambutol | |
| ubiA | 4269220 | p.Ala205Lys | missense_variant | 0.26 | ethambutol | |
| ubiA | 4269222 | c.612T>C | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
| aftB | 4269234 | c.-398A>G | upstream_gene_variant | 0.31 | ethambutol | |
| aftB | 4269242 | c.-406C>T | upstream_gene_variant | 0.31 | ethambutol | |
| ubiA | 4269243 | p.His197Gln | missense_variant | 0.3 | ethambutol | |
| aftB | 4269249 | c.-413G>A | upstream_gene_variant | 0.31 | ethambutol | |
| aftB | 4269258 | c.-422C>T | upstream_gene_variant | 0.27 | ethambutol | |
| ethA | 4326644 | p.Asp277Gly | missense_variant | 1.0 | ethionamide | |
| whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
| capreomycin | Not assoc w R | |||||
| amikacin | Not assoc w R | |||||
| whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin |
