Run ID: ERR11466146
Sample name:
Date: 2024-10-05T02:39:05.635045
Number of reads: 3774078
Percentage reads mapped: 96.19
Median coverage: 113.0
Strain: lineage4.3.4.2.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.3 | Euro-American (LAM) | None | 0.99 |
La1.2.BCG | M.bovis | None | 0.1 |
lineage4 | Euro-American | None | 0.97 |
lineage4.3.4.2.1 | Euro-American (LAM) | RD174 | 0.97 |
lineage4.3.4 | Euro-American (LAM) | RD174 | 1.0 |
lineage4.3.4.2 | Euro-American (LAM) | RD174 | 0.9 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.29 | streptomycin | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrB | 6140 | p.Val301Leu | missense_variant | 0.94 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9224 | c.1923C>T | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>T | synonymous_variant | 0.14 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.14 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9278 | c.1977G>A | synonymous_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9300 | p.Ala667Ser | missense_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.15 | ethionamide | |
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 0.2 | ethionamide | |
Rv0565c | 657592 | c.-122A>C | upstream_gene_variant | 0.15 | ethionamide | |
Rv0565c | 657607 | c.-138_-137insCA | upstream_gene_variant | 0.15 | ethionamide | |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 0.18 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.19 | ethionamide | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.19 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.18 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.19 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.24 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.26 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.27 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.22 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.24 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.25 | isoniazid | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.15 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.13 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.14 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.15 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.17 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.27 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.26 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoB | 760541 | c.735G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.15 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.18 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.17 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760949 | c.1143C>T | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.17 | rifampicin | |
rpoB | 761373 | p.Val523Gln | missense_variant | 0.14 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761439 | p.Asp545Lys | missense_variant | 0.17 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.16 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.17 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761639 | c.1833G>A | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761720 | c.1914C>G | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.22 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.22 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.2 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.28 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.28 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.17 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.18 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762314 | c.2508C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.27 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.31 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.21 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoB | 762729 | p.Gln975Lys | missense_variant | 0.19 | rifampicin | |
rpoB | 762736 | p.Ala977Glu | missense_variant | 0.17 | rifampicin | |
rpoB | 762744 | p.Gln980Ala | missense_variant | 0.17 | rifampicin | |
rpoB | 762750 | p.Leu982Met | missense_variant | 0.19 | rifampicin | |
rpoB | 762753 | c.2947T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 762758 | c.-612G>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762785 | p.Asp993Glu | missense_variant | 0.18 | rifampicin | Uncertain significance |
rpoB | 762788 | c.2982G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762789 | p.Leu995Met | missense_variant | 0.18 | rifampicin | Uncertain significance |
rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoB | 762810 | p.Ala1002Ser | missense_variant | 0.17 | rifampicin | |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.17 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.28 | rifampicin | |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.33 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.34 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.32 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.15 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.15 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.15 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.24 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.28 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.25 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.24 | rifampicin | |
rpoC | 763877 | c.508_510delCTAinsTTG | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763951 | c.582G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 763960 | c.591T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 763991 | p.Ile208Leu | missense_variant | 0.18 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.22 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.2 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.29 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.39 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.28 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 765292 | c.1923G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.24 | rifampicin | Uncertain significance |
rpoC | 765329 | p.Ser654Gly | missense_variant | 0.24 | rifampicin | |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.28 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.28 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.38 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.35 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.39 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766030 | c.2661C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766036 | c.2667C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.26 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.24 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 766168 | c.2799C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766174 | p.Asn935Lys | missense_variant | 0.16 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.16 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.18 | rifampicin | |
rpoC | 766288 | c.2919C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766303 | c.2934C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766327 | c.2958C>A | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766393 | c.3024C>T | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766484 | p.Val1039Ile | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.2 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.14 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.14 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.21 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.16 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.24 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.14 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.14 | bedaquiline | |
clofazimine | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.16 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.15 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.15 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.15 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.15 | streptomycin | Uncertain significance |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.22 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.2 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.21 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.2 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.17 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.17 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 0.15 | linezolid | |
rplC | 800875 | p.Val23Ile | missense_variant | 0.14 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.15 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.16 | linezolid | |
rplC | 800892 | c.84G>C | synonymous_variant | 0.16 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.17 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.15 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.16 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.15 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.15 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.14 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.14 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.14 | linezolid | |
fbiC | 1303641 | c.711C>T | synonymous_variant | 0.14 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.15 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.16 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.16 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.16 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472045 | n.200T>A | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472581 | n.736A>G | non_coding_transcript_exon_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.21 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474409 | n.756_766delACCCACACGCG | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1474427 | n.770A>C | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1474429 | n.772G>C | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1474435 | n.780_783delGAAT | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1674006 | c.-196T>G | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674015 | c.-187C>T | upstream_gene_variant | 0.14 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1674042 | c.-160G>T | upstream_gene_variant | 0.14 | isoniazid | |
ethionamide | ||||||
inhA | 1674063 | c.-139G>C | upstream_gene_variant | 0.15 | isoniazid | |
ethionamide | ||||||
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834262 | p.Ser241Thr | missense_variant | 0.14 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.15 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.25 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.26 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.27 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.24 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.17 | linezolid | |
tsnR | 1853423 | c.-183C>T | upstream_gene_variant | 0.17 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.22 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.17 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.17 | isoniazid | |
kasA | 2518162 | c.48G>A | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518174 | c.60A>G | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 0.18 | isoniazid | |
kasA | 2518199 | p.Ile29Val | missense_variant | 0.17 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.15 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518693 | c.579C>G | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.15 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518906 | c.792A>G | synonymous_variant | 0.15 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.15 | isoniazid | |
ahpC | 2726600 | c.408T>C | synonymous_variant | 0.15 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.17 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 0.17 | isoniazid | |
Rv2477c | 2782450 | c.1593C>A | synonymous_variant | 0.14 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782453 | c.1590C>G | synonymous_variant | 0.14 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782928 | p.Thr372Lys | missense_variant | 0.14 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783275 | c.768C>G | synonymous_variant | 0.14 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783309 | p.Leu245Pro | missense_variant | 0.81 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783314 | c.729C>G | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783335 | c.708C>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783401 | c.642C>T | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.16 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783557 | c.486T>C | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.14 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.15 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2752c | 3064860 | c.1332G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064863 | c.1329G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065979 | c.213T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065993 | p.Val67Ile | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3065994 | c.198T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066002 | p.Met64Leu | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066009 | c.183G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066018 | c.174T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066024 | c.168T>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066040 | p.Gly51Thr | missense_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066042 | c.150T>C | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066045 | c.147T>C | synonymous_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066050 | p.Leu48Met | missense_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066054 | c.138T>G | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066467 | c.-276G>A | upstream_gene_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066522 | c.-331C>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066531 | c.-340C>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066839 | c.-648A>G | upstream_gene_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066855 | c.-664T>C | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067661 | c.285C>G | synonymous_variant | 0.14 | para-aminosalicylic_acid | |
thyA | 3073868 | p.Thr202Ala | missense_variant | 0.96 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612009 | p.Ala370Thr | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.14 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625711 | c.903C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.16 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.18 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.14 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.14 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.14 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627071 | c.279G>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627299 | c.-688_-686delTTGinsCTA | upstream_gene_variant | 0.14 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627917 | c.-568G>C | upstream_gene_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627920 | c.-571A>G | upstream_gene_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
fbiA | 3641440 | p.Gly300Arg | missense_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | Uncertain significance | |||||
alr | 3840719 | c.702A>G | synonymous_variant | 1.0 | cycloserine | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.19 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.2 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.2 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.18 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoA | 3878713 | c.-206G>A | upstream_gene_variant | 0.15 | rifampicin | Uncertain significance |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.14 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.17 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.26 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.28 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.19 | rifampicin | Uncertain significance |
rpoA | 3878884 | c.-377C>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.15 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.16 | rifampicin | Uncertain significance |
rpoA | 3878920 | c.-413C>T | upstream_gene_variant | 0.15 | rifampicin | |
rpoA | 3878974 | c.-469_-467delATCinsGTG | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.15 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.16 | rifampicin | |
clpC1 | 4038287 | c.2418C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038433 | c.2272C>T | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038434 | c.2271G>A | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.17 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039124 | c.1581C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.17 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.18 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039982 | c.723G>A | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.17 | pyrazinamide | |
glpK | 4139597 | c.159C>G | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139601 | p.Arg52Gln | missense_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4238953 | c.-910G>A | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
embC | 4240699 | c.837C>G | synonymous_variant | 0.16 | ethambutol | Not assoc w R - Interim |
embC | 4240780 | c.918T>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.17 | ethambutol | |
embC | 4240828 | c.966G>A | synonymous_variant | 0.17 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.17 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.15 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.17 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.15 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.15 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.15 | ethambutol | |
embC | 4241449 | c.1587C>G | synonymous_variant | 0.14 | ethambutol | |
embC | 4241453 | p.Ile531Val | missense_variant | 0.15 | ethambutol | |
embC | 4241479 | c.1617C>G | synonymous_variant | 0.16 | ethambutol | |
embC | 4241480 | c.1618T>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 0.96 | ethambutol | Not assoc w R |
embA | 4242754 | c.-479G>C | upstream_gene_variant | 0.15 | ethambutol | |
embC | 4242764 | p.Val968Leu | missense_variant | 0.16 | ethambutol | |
embC | 4242779 | p.Asn973Asp | missense_variant | 0.19 | ethambutol | |
embC | 4242791 | p.Ala977Ser | missense_variant | 0.19 | ethambutol | |
embA | 4242796 | c.-437G>C | upstream_gene_variant | 0.18 | ethambutol | |
embA | 4242799 | c.-434T>C | upstream_gene_variant | 0.17 | ethambutol | |
embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.15 | ethambutol | |
embA | 4246080 | p.Pro950Ser | missense_variant | 0.16 | ethambutol | |
embA | 4246164 | c.2932T>C | synonymous_variant | 0.15 | ethambutol | Not assoc w R - Interim |
embB | 4246184 | c.-330A>C | upstream_gene_variant | 0.17 | ethambutol | |
embB | 4246196 | c.-318C>G | upstream_gene_variant | 0.2 | ethambutol | |
embB | 4246205 | c.-309A>G | upstream_gene_variant | 0.19 | ethambutol | |
embB | 4246211 | c.-303T>C | upstream_gene_variant | 0.17 | ethambutol | |
embB | 4246217 | c.-297G>A | upstream_gene_variant | 0.17 | ethambutol | |
embA | 4246220 | c.2988T>C | synonymous_variant | 0.15 | ethambutol | Not assoc w R - Interim |
embB | 4246223 | c.-291C>T | upstream_gene_variant | 0.15 | ethambutol | |
embA | 4246227 | p.Ile999Val | missense_variant | 0.15 | ethambutol | |
embA | 4246235 | c.3003G>A | synonymous_variant | 0.16 | ethambutol | Not assoc w R - Interim |
embA | 4246242 | p.Gln1004Glu | missense_variant | 0.15 | ethambutol | |
embB | 4246250 | c.-264G>C | upstream_gene_variant | 0.16 | ethambutol | |
embB | 4246256 | c.-258G>T | upstream_gene_variant | 0.17 | ethambutol | |
embB | 4246259 | c.-255G>C | upstream_gene_variant | 0.17 | ethambutol | |
embA | 4246264 | p.His1011Arg | missense_variant | 0.15 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 0.18 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.15 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.15 | ethambutol | |
embB | 4248035 | p.Val508Ile | missense_variant | 0.17 | ethambutol | |
embB | 4248040 | c.1527C>G | synonymous_variant | 0.18 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.19 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 0.19 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.26 | ethambutol | |
embB | 4248111 | p.Val533Ala | missense_variant | 0.19 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.15 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4408156 | p.Leu16Arg | missense_variant | 1.0 | streptomycin | Not assoc w R |