TB-Profiler result

Run: SRR10869071
Summary

Run ID: SRR10869071

Sample name:

Date: 02-04-2023 19:38:14

Number of reads: 1492202

Percentage reads mapped: 59.39

Strain: lineage2.2.1

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 0.91 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.41 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.6 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.48 kanamycin, capreomycin, aminoglycosides, amikacin
fabG1 1673425 c.-15C>T upstream_gene_variant 1.0 isoniazid, ethionamide
pncA 2288933 p.Tyr103* stop_gained 1.0 pyrazinamide
ethR 4327831 p.Ala95Thr missense_variant 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.32
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoB 761015 c.1209G>C synonymous_variant 0.13
rpoB 761027 c.1221A>G synonymous_variant 0.14
rpoB 761032 p.Gln409Leu missense_variant 0.12
rpoB 761037 c.1231T>C synonymous_variant 0.12
rpoB 761051 c.1245G>T synonymous_variant 0.12
rpoB 761057 c.1251G>C synonymous_variant 0.12
rpoB 761058 p.Val418Thr missense_variant 0.12
rpoB 761063 c.1257C>G synonymous_variant 0.12
rpoB 761084 c.1278C>A synonymous_variant 0.13
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.12
rpoB 761096 c.1290G>C synonymous_variant 0.12
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.12
rpoB 761102 c.1296A>G synonymous_variant 0.14
rpoB 761132 c.1326G>C synonymous_variant 0.11
rpoB 762026 c.2220G>C synonymous_variant 0.14
rpoB 762053 c.2247T>C synonymous_variant 0.14
rpoB 762057 p.Ile751Val missense_variant 0.13
rpoB 762062 c.2256T>C synonymous_variant 0.14
rpoB 762065 c.2259T>C synonymous_variant 0.13
rpoB 762080 c.2274G>C synonymous_variant 0.13
rpoB 762101 c.2295C>G synonymous_variant 0.2
rpoB 762114 p.Ile770Val missense_variant 0.18
rpoB 762117 p.Ser771Gly missense_variant 0.18
rpoB 762125 p.Glu773Asp missense_variant 0.2
rpoB 762131 c.2325C>G synonymous_variant 0.2
rpoB 762137 c.2331C>T synonymous_variant 0.19
rpoB 762140 c.2334G>C synonymous_variant 0.2
rpoB 762143 c.2337T>C synonymous_variant 0.21
rpoB 762149 c.2343G>C synonymous_variant 0.21
rpoB 762156 p.Val784Ile missense_variant 0.21
rpoB 762167 c.2361T>C synonymous_variant 0.21
rpoB 762175 c.2370_2372delTCG disruptive_inframe_deletion 0.16
rpoB 762181 c.2375_2376insGCC disruptive_inframe_insertion 0.15
rpoB 762185 c.2379G>C synonymous_variant 0.15
rpoB 762218 c.2412T>C synonymous_variant 0.12
rpoC 762887 c.-483G>C upstream_gene_variant 0.13
rpoB 762909 p.Ile1035Leu missense_variant 0.18
rpoC 762923 c.-447C>G upstream_gene_variant 0.24
rpoC 762929 c.-441G>T upstream_gene_variant 0.25
rpoC 762947 c.-423C>G upstream_gene_variant 0.27
rpoC 762971 c.-399G>C upstream_gene_variant 0.36
rpoC 762980 c.-390T>C upstream_gene_variant 0.38
rpoC 762989 c.-381G>C upstream_gene_variant 0.38
rpoC 762995 c.-375G>C upstream_gene_variant 0.36
rpoB 763005 p.Cys1067Val missense_variant 0.37
rpoB 763014 p.Met1070Leu missense_variant 0.38
rpoB 763017 p.Gln1071Glu missense_variant 0.39
rpoC 763028 c.-342T>C upstream_gene_variant 0.38
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.4
rpoC 763053 c.-317T>C upstream_gene_variant 0.4
rpoC 763070 c.-300T>C upstream_gene_variant 0.39
rpoB 763075 p.Thr1090Ile missense_variant 0.37
rpoB 763077 p.Val1091Ser missense_variant 0.36
rpoC 763088 c.-282C>G upstream_gene_variant 0.37
rpoC 763115 c.-255T>C upstream_gene_variant 0.32
rpoC 763127 c.-243G>C upstream_gene_variant 0.25
rpoC 763133 c.-237G>C upstream_gene_variant 0.22
rpoC 763136 c.-234C>G upstream_gene_variant 0.19
rpoC 763142 c.-228C>G upstream_gene_variant 0.19
rpoC 763148 c.-222G>C upstream_gene_variant 0.18
rpoB 763152 p.Lys1116Arg missense_variant 0.18
rpoC 763166 c.-204A>G upstream_gene_variant 0.2
rpoC 763169 c.-201A>G upstream_gene_variant 0.2
rpoB 763170 p.Leu1122Met missense_variant 0.19
rpoC 763187 c.-183C>G upstream_gene_variant 0.17
rpoC 763456 c.87A>G synonymous_variant 0.14
rpoC 763462 c.93G>C synonymous_variant 0.2
rpoC 763468 c.99G>C synonymous_variant 0.21
rpoC 763483 c.114G>C synonymous_variant 0.21
rpoC 763486 c.117T>G synonymous_variant 0.21
rpoC 763492 c.123G>C synonymous_variant 0.21
rpoC 763497 p.Lys43Met missense_variant 0.23
rpoC 763517 p.Lys50Arg missense_variant 0.2
rpoC 763528 c.159G>T synonymous_variant 0.2
rpoC 763531 c.162G>C synonymous_variant 0.21
rpoC 763534 c.165T>C synonymous_variant 0.2
rpoC 763537 c.168C>G synonymous_variant 0.22
rpoC 763546 c.177A>G synonymous_variant 0.26
rpoC 763555 c.186C>T synonymous_variant 0.7
rpoC 763570 c.201G>C synonymous_variant 0.31
rpoC 763573 c.204G>C synonymous_variant 0.3
rpoC 763589 p.Ile74Val missense_variant 0.31
rpoC 763609 c.240C>G synonymous_variant 0.23
rpoC 763614 c.246_251delGACCCG disruptive_inframe_deletion 0.19
rpoC 763622 p.Ala85Thr missense_variant 0.18
rpoC 763627 c.258_259insTCCTCC conservative_inframe_insertion 0.18
rpoC 763633 c.264T>C synonymous_variant 0.2
rpoC 763642 c.273G>C synonymous_variant 0.2
rpoC 763652 p.Ile95Val missense_variant 0.2
rpoC 763660 c.291T>C synonymous_variant 0.19
rpoC 763663 c.294C>G synonymous_variant 0.2
rpoC 763666 c.297G>C synonymous_variant 0.2
rpoC 763696 c.327T>C synonymous_variant 0.14
rpoC 764338 p.Glu323Asp missense_variant 0.13
rpoC 764359 c.990C>G synonymous_variant 0.16
rpoC 764371 c.1002G>C synonymous_variant 0.14
rpoC 764485 c.1116G>C synonymous_variant 0.14
rpoC 764497 c.1128A>G synonymous_variant 0.17
rpoC 764500 c.1131C>G synonymous_variant 0.14
rpoC 764503 c.1134G>C synonymous_variant 0.14
rpoC 764507 p.Ala380Ser missense_variant 0.17
rpoC 764521 c.1152T>C synonymous_variant 0.14
rpoC 764527 c.1158C>T synonymous_variant 0.16
rpoC 764536 c.1167G>C synonymous_variant 0.14
rpoC 764539 c.1170C>G synonymous_variant 0.14
rpoC 764545 c.1176C>G synonymous_variant 0.19
rpoC 764548 c.1179G>C synonymous_variant 0.2
rpoC 764551 c.1182G>C synonymous_variant 0.26
rpoC 764566 c.1197C>G synonymous_variant 0.29
rpoC 764575 c.1206T>C synonymous_variant 0.28
rpoC 764581 c.1212T>C synonymous_variant 0.32
rpoC 764582 p.Leu405Met missense_variant 0.32
rpoC 764605 c.1236G>C synonymous_variant 0.34
rpoC 764611 c.1242G>C synonymous_variant 0.33
rpoC 764623 c.1254C>G synonymous_variant 0.29
rpoC 764632 c.1263T>C synonymous_variant 0.28
rpoC 764635 c.1266C>G synonymous_variant 0.27
rpoC 764644 c.1275G>C synonymous_variant 0.28
rpoC 764646 p.Gly426Ala missense_variant 0.28
rpoC 764650 c.1281G>C synonymous_variant 0.28
rpoC 764653 c.1284G>C synonymous_variant 0.28
rpoC 764656 c.1287C>G synonymous_variant 0.27
rpoC 764662 c.1293G>C synonymous_variant 0.26
rpoC 764663 p.Val432Asn missense_variant 0.26
rpoC 764668 c.1299C>T synonymous_variant 0.25
rpoC 764677 c.1308C>G synonymous_variant 0.25
rpoC 764705 p.Leu446Gly missense_variant 0.22
rpoC 764731 c.1362G>C synonymous_variant 0.21
rpoC 764737 c.1368G>C synonymous_variant 0.19
rpoC 764746 c.1377G>C synonymous_variant 0.16
rpoC 764752 c.1383G>C synonymous_variant 0.17
rpoC 764755 p.Asp462Glu missense_variant 0.15
rpoC 764760 p.Asn464Ser missense_variant 0.13
rpoC 764764 c.1395T>C synonymous_variant 0.14
rpoC 764767 c.1398G>C synonymous_variant 0.14
rpoC 764774 p.Ile469Val missense_variant 0.14
rpoC 764780 p.Ser471Ala missense_variant 0.14
rpoC 764797 c.1428G>C synonymous_variant 0.14
rpoC 764804 p.Gln479Ala missense_variant 0.14
rpoC 764813 p.Gln482Glu missense_variant 0.15
rpoC 764818 c.1449G>C synonymous_variant 0.16
rpoC 764824 c.1455T>C synonymous_variant 0.16
rpoC 764833 c.1464A>G synonymous_variant 0.14
rpoC 764869 c.1500C>T synonymous_variant 0.12
rpoC 764872 c.1503A>G synonymous_variant 0.12
rpoC 764875 c.1506C>G synonymous_variant 0.12
rpoC 764887 c.1518G>C synonymous_variant 0.11
rpoC 764893 c.1524T>C synonymous_variant 0.1
rpoC 766488 p.Pro1040Leu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 778979 c.-74G>T upstream_gene_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472092 n.247C>T non_coding_transcript_exon_variant 0.18
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.25
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.26
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.26
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.28
rrs 1472120 n.275G>A non_coding_transcript_exon_variant 0.37
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.37
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.47
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.48
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.51
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.49
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.27
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.15
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.16
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.15
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.15
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.15
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.16
rrs 1472312 n.467_468insA non_coding_transcript_exon_variant 0.14
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.14
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.15
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.15
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.16
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.18
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.18
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.21
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.21
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.19
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.23
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.21
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.21
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.21
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.21
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.21
rrs 1472591 n.746G>A non_coding_transcript_exon_variant 0.25
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.28
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.37
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.38
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.42
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.43
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.33
rrs 1472674 n.829T>G non_coding_transcript_exon_variant 0.33
rrs 1472675 n.830T>A non_coding_transcript_exon_variant 0.33
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.34
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.42
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.51
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.32
rrs 1472791 n.946G>T non_coding_transcript_exon_variant 0.32
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.24
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.24
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.24
rrs 1472840 n.995A>T non_coding_transcript_exon_variant 0.2
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.18
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.41
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.41
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.41
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.41
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.44
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.41
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.42
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.4
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.51
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.52
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.54
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.53
rrs 1473065 n.1220C>A non_coding_transcript_exon_variant 0.53
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.52
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.52
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.51
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.48
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.49
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.49
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.49
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.49
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.49
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.49
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.51
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.52
rrs 1473132 n.1287T>C non_coding_transcript_exon_variant 0.52
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.52
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.47
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.58
rrs 1473286 n.1441C>T non_coding_transcript_exon_variant 0.53
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 0.54
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.51
rrl 1473391 n.-267C>T upstream_gene_variant 0.11
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.16
rrl 1473789 n.132G>C non_coding_transcript_exon_variant 0.34
rrl 1473797 n.140G>C non_coding_transcript_exon_variant 0.34
rrl 1473806 n.149C>G non_coding_transcript_exon_variant 0.34
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.32
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.32
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 0.32
rrl 1473828 n.171_172insCA non_coding_transcript_exon_variant 0.34
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.35
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.32
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.27
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.26
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.18
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.2
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.25
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.26
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.27
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.24
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.24
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.3
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.3
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.33
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.35
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.46
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.4
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.39
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.37
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.32
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.29
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.27
rrl 1474352 n.696_699delACAT non_coding_transcript_exon_variant 0.3
rrl 1474359 n.703_704insGTGG non_coding_transcript_exon_variant 0.26
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.26
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.2
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.19
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.27
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.31
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.32
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.32
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.33
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.33
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.31
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.31
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.33
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.32
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.13
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.32
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.33
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.17
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.16
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.15
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.16
rrl 1474777 n.1120T>A non_coding_transcript_exon_variant 0.26
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.25
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.25
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.27
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.36
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.37
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.36
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.37
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.38
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.38
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.27
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.19
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.42
rrl 1475706 n.2049A>C non_coding_transcript_exon_variant 0.43
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.39
rrl 1475767 n.2110G>A non_coding_transcript_exon_variant 0.36
rrl 1475769 n.2112_2113insTC non_coding_transcript_exon_variant 0.35
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.37
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.43
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.43
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.43
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.45
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.46
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.48
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.47
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.43
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.4
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.35
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.33
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.33
rrl 1475982 n.2325G>A non_coding_transcript_exon_variant 0.36
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.36
rrl 1475996 n.2339T>G non_coding_transcript_exon_variant 0.31
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.29
rrl 1476026 n.2369T>G non_coding_transcript_exon_variant 0.15
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.13
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.21
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.21
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.29
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.33
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.33
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 0.3
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.3
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.29
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.28
rrl 1476261 n.2604A>G non_coding_transcript_exon_variant 0.27
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.28
rrl 1476268 n.2611A>G non_coding_transcript_exon_variant 0.28
rrl 1476275 n.2618T>C non_coding_transcript_exon_variant 0.29
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.29
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.29
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.31
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.35
rrl 1476299 n.2642C>A non_coding_transcript_exon_variant 0.33
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.33
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.33
rrl 1476308 n.2651G>T non_coding_transcript_exon_variant 0.39
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.54
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.56
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.55
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.58
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.57
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.57
rrl 1476443 n.2786G>A non_coding_transcript_exon_variant 0.6
rrl 1476455 n.2798C>T non_coding_transcript_exon_variant 0.59
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.54
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.43
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.36
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.3
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.3
rrl 1476528 n.2871A>T non_coding_transcript_exon_variant 0.3
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.31
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.32
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.32
rrl 1476539 n.2882A>T non_coding_transcript_exon_variant 0.32
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.31
rrl 1476572 n.2915G>T non_coding_transcript_exon_variant 0.3
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.28
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.18
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.18
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.12
rpsA 1833955 c.414G>C synonymous_variant 0.14
rpsA 1833959 p.Leu140Val missense_variant 0.15
rpsA 1833970 c.429G>C synonymous_variant 0.19
rpsA 1833979 c.438T>C synonymous_variant 0.2
rpsA 1833985 c.444G>C synonymous_variant 0.25
rpsA 1833988 c.447C>G synonymous_variant 0.26
rpsA 1833994 c.453G>C synonymous_variant 0.26
rpsA 1833997 c.456G>C synonymous_variant 0.27
rpsA 1834012 c.471G>C synonymous_variant 0.3
rpsA 1834015 c.474G>C synonymous_variant 0.28
rpsA 1834034 p.Ile165Val missense_variant 0.29
rpsA 1834040 p.Lys167Gln missense_variant 0.28
rpsA 1834054 c.513C>G synonymous_variant 0.27
rpsA 1834093 c.552G>C synonymous_variant 0.2
rpsA 1834102 c.561T>C synonymous_variant 0.15
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834222 c.681T>C synonymous_variant 0.13
rpsA 1834231 c.690T>C synonymous_variant 0.16
rpsA 1834234 c.693G>C synonymous_variant 0.16
rpsA 1834240 c.699T>C synonymous_variant 0.16
rpsA 1834249 c.708T>C synonymous_variant 0.15
rpsA 1834307 p.Asp256His missense_variant 0.11
rpsA 1834390 c.849G>C synonymous_variant 0.12
rpsA 1834395 p.Arg285Gln missense_variant 0.12
rpsA 1834398 p.His286Leu missense_variant 0.12
rpsA 1834411 c.870T>C synonymous_variant 0.16
rpsA 1834417 c.876G>C synonymous_variant 0.16
rpsA 1834423 c.882G>C synonymous_variant 0.16
rpsA 1834424 p.Gln295Glu missense_variant 0.16
rpsA 1834427 p.Ile296Val missense_variant 0.17
rpsA 1834435 c.894G>C synonymous_variant 0.16
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.18
rpsA 1834456 c.915T>C synonymous_variant 0.16
rpsA 1834459 c.918G>C synonymous_variant 0.15
rpsA 1834465 c.924T>C synonymous_variant 0.15
rpsA 1834468 c.927A>G synonymous_variant 0.14
rpsA 1834486 p.Glu315Asp missense_variant 0.16
rpsA 1834489 c.948T>C synonymous_variant 0.16
rpsA 1834501 c.960G>C synonymous_variant 0.16
rpsA 1834523 p.Glu328Gln missense_variant 0.16
rpsA 1834528 c.987T>C synonymous_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.38
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
rpoA 3877866 c.642G>C synonymous_variant 0.17
rpoA 3877875 c.633T>G synonymous_variant 0.18
rpoA 3877881 c.627G>C synonymous_variant 0.17
rpoA 3877886 p.Leu208Val missense_variant 0.17
rpoA 3877896 c.612G>C synonymous_variant 0.18
rpoA 3877905 p.Ser201Ala missense_variant 0.2
rpoA 3877908 p.Asn200Pro missense_variant 0.19
rpoA 3877920 c.588G>C synonymous_variant 0.19
rpoA 3877926 p.Leu194Val missense_variant 0.19
rpoA 3877932 c.576G>C synonymous_variant 0.18
rpoA 3877962 c.546G>T synonymous_variant 0.17
rpoA 3877968 c.540C>G synonymous_variant 0.18
rpoA 3877971 p.Asp179Glu missense_variant 0.18
rpoA 3877974 c.534G>C synonymous_variant 0.17
rpoA 3877989 c.519A>G synonymous_variant 0.2
rpoA 3877992 c.516C>G synonymous_variant 0.18
rpoA 3877998 c.510G>C synonymous_variant 0.19
rpoA 3878001 c.507A>G synonymous_variant 0.13
clpC1 4039593 p.Arg371Lys missense_variant 0.11
clpC1 4039616 c.1089G>C synonymous_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0