Run ID: SRR22175249
Sample name:
Date: 2024-04-15T15:08:54.493839
Number of reads: 1015419
Percentage reads mapped: 45.11
Median coverage: 30.0
Strain: lineage2.2.1
Spoligotype:
Drug-resistance: Pre-XDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage2 | East-Asian | RD105 | 0.99 |
lineage2.2.1 | East-Asian (Beijing) | RD105;RD207;RD181 | 1.0 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Ser450Leu | Assoc w R | |
isoniazid | katG | p.Ser315Thr | Assoc w R | High-level resistance |
ethambutol | embB | p.Met306Val | Assoc w R | |
pyrazinamide | pncA | p.Leu159Arg | Assoc w R | |
streptomycin | rpsL | p.Lys43Arg | Assoc w R | |
rrs | n.799C>T | Uncertain significance | Mutation from literature | |
fluoroquinolones | ||||
moxifloxacin | gyrA | p.Asp94Gly | Assoc w R | High-level resistance |
ofloxacin | ||||
levofloxacin | gyrA | p.Asp94Gly | Assoc w R | |
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
capreomycin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
kanamycin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
cycloserine | ||||
ethionamide | ethA | c.549_551delTGG | Mutation from literature | |
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
gyrA | 7582 | p.Asp94Gly | missense_variant | 0.97 | moxifloxacin | Assoc w R | High-level resistance |
levofloxacin | Assoc w R | ||||||
rpoB | 761155 | p.Ser450Leu | missense_variant | 0.94 | rifampicin | Assoc w R | |
rpsL | 781687 | p.Lys43Arg | missense_variant | 0.95 | streptomycin | Assoc w R | |
rrs | 1472644 | n.799C>T | non_coding_transcript_exon_variant | 0.63 | streptomycin | Uncertain significance | Mutation from literature |
rrs | 1473247 | n.1402C>A | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance | Mutation from literature |
amikacin | Uncertain significance | Mutation from literature | |||||
kanamycin | Uncertain significance | Mutation from literature | |||||
rrs | 1473329 | n.1484G>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Assoc w R | |
kanamycin | Assoc w R | ||||||
amikacin | Assoc w R | ||||||
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
pncA | 2288766 | p.Leu159Arg | missense_variant | 1.0 | pyrazinamide | Assoc w R | |
embB | 4247429 | p.Met306Val | missense_variant | 1.0 | ethambutol | Assoc w R | |
ethA | 4326922 | c.549_551delTGG | disruptive_inframe_deletion | 1.0 | ethionamide | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
fgd1 | 491290 | p.Val170Met | missense_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Uncertain significance | |||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
mshA | 575907 | p.Ala187Val | missense_variant | 1.0 | ethionamide | Not assoc w R |
isoniazid | Not assoc w R | |||||
ccsA | 620625 | p.Ile245Met | missense_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Uncertain significance | |||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 1.0 | ethionamide | Uncertain significance |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760973 | c.1167G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 760988 | c.1182C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762057 | p.Ile751Val | missense_variant | 0.28 | rifampicin | Uncertain significance |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762084 | p.Ala760Pro | missense_variant | 0.27 | rifampicin | |
rpoB | 762110 | c.2304G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.31 | rifampicin | Uncertain significance |
rpoB | 762122 | p.Asp772Glu | missense_variant | 0.34 | rifampicin | |
rpoB | 762128 | c.2322G>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762152 | c.2346C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762156 | c.2350_2352delGTGinsAC | frameshift_variant&missense_variant | 0.35 | rifampicin | |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 762178 | p.Arg791Gln | missense_variant | 0.14 | rifampicin | |
rpoB | 762181 | p.Asp792Ala | missense_variant | 0.14 | rifampicin | |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 762189 | c.2383_2385delATCinsCG | frameshift_variant&missense_variant | 0.3 | rifampicin | |
rpoB | 762194 | c.2388G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 762197 | c.2391C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 762209 | c.2403C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762212 | c.2406G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762236 | c.2430G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762245 | c.2439G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.14 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.12 | rifampicin | |
rpoB | 762273 | p.Ala823Ser | missense_variant | 0.12 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 763531 | c.162G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R |
rpoC | 763534 | c.165T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763537 | c.168C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 763578 | p.Phe70Tyr | missense_variant | 0.19 | rifampicin | |
rpoC | 763609 | c.240C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763615 | c.246G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763618 | c.249C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763660 | c.291T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763672 | c.303C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763709 | c.340C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 0.17 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 0.17 | rifampicin | |
rpoC | 764441 | p.Ile358Leu | missense_variant | 0.17 | rifampicin | |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764485 | c.1116G>C | synonymous_variant | 0.11 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764498 | p.Ser377Ala | missense_variant | 0.24 | rifampicin | |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764533 | c.1164C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764542 | c.1173C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764573 | c.1204_1206delCTTinsAC | frameshift_variant&missense_variant | 0.26 | rifampicin | |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764582 | p.Leu405Met | missense_variant | 0.47 | rifampicin | |
rpoC | 764605 | c.1236G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764623 | c.1254C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764662 | c.1293G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764671 | c.1302G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764672 | p.Gln435Thr | missense_variant | 0.3 | rifampicin | |
rpoC | 764703 | p.Lys445Arg | missense_variant | 0.45 | rifampicin | Uncertain significance |
rpoC | 764706 | p.Leu446Gln | missense_variant | 0.52 | rifampicin | Uncertain significance |
rpoC | 764713 | c.1344G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764714 | c.1345C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764719 | c.1350G>A | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764722 | c.1353G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764746 | c.1377G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764749 | c.1380G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764780 | c.1411_1413delAGCinsTCG | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764843 | p.Ala492Thr | missense_variant | 0.29 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776182 | p.Asp767Asn | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R | |||||
mmpS5 | 779615 | c.-710C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
Rv1129c | 1253930 | p.Phe202Tyr | missense_variant | 1.0 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
Rv1258c | 1406760 | c.580_581insC | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
isoniazid | Uncertain significance | |||||
pyrazinamide | Uncertain significance | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.59 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.56 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472225 | n.380C>A | non_coding_transcript_exon_variant | 0.19 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Uncertain significance | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472259 | n.414C>A | non_coding_transcript_exon_variant | 0.21 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472285 | n.440A>G | non_coding_transcript_exon_variant | 0.22 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.33 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472289 | n.444T>C | non_coding_transcript_exon_variant | 0.38 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472290 | n.445C>G | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472293 | n.448C>A | non_coding_transcript_exon_variant | 0.53 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472297 | n.453_465delGTCCGGGTTCTCT | non_coding_transcript_exon_variant | 0.56 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472313 | n.468delGinsAA | non_coding_transcript_exon_variant | 0.42 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 0.56 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472324 | n.479G>C | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472325 | n.480G>C | non_coding_transcript_exon_variant | 0.24 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472338 | n.493A>G | non_coding_transcript_exon_variant | 0.33 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.58 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472513 | n.668T>C | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.43 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472549 | n.704G>A | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472558 | n.713G>A | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472569 | n.724G>A | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472581 | n.736A>T | non_coding_transcript_exon_variant | 0.41 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472582 | n.737G>A | non_coding_transcript_exon_variant | 0.2 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472584 | n.739A>T | non_coding_transcript_exon_variant | 0.33 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472597 | n.752G>A | non_coding_transcript_exon_variant | 0.24 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472607 | n.762G>A | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472655 | n.810G>T | non_coding_transcript_exon_variant | 0.6 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472660 | n.815T>C | non_coding_transcript_exon_variant | 0.63 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.18 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472673 | n.828T>G | non_coding_transcript_exon_variant | 0.55 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472674 | n.829T>G | non_coding_transcript_exon_variant | 0.44 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472675 | n.830T>A | non_coding_transcript_exon_variant | 0.37 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472677 | n.832C>A | non_coding_transcript_exon_variant | 0.53 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472692 | n.847T>C | non_coding_transcript_exon_variant | 0.36 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472697 | n.852T>C | non_coding_transcript_exon_variant | 0.19 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.14 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.45 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472952 | n.1107T>C | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472955 | n.1110C>T | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.43 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 0.68 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 0.67 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472989 | n.1144G>A | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.67 | streptomycin | Uncertain significance |
kanamycin | Not assoc w R | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.73 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.73 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.73 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.71 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473082 | n.1237G>A | non_coding_transcript_exon_variant | 0.45 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473089 | n.1244A>T | non_coding_transcript_exon_variant | 0.4 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473091 | n.1246G>T | non_coding_transcript_exon_variant | 0.26 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473093 | n.1248C>T | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.37 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.65 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473109 | n.1264T>C | non_coding_transcript_exon_variant | 0.29 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.64 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.64 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473115 | n.1270G>T | non_coding_transcript_exon_variant | 0.34 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473120 | n.1275C>A | non_coding_transcript_exon_variant | 0.31 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.64 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473122 | n.1277T>A | non_coding_transcript_exon_variant | 0.32 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473129 | n.1284C>T | non_coding_transcript_exon_variant | 0.34 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473147 | n.1302G>T | non_coding_transcript_exon_variant | 0.35 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473164 | n.1319C>A | non_coding_transcript_exon_variant | 0.33 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473252 | n.1407T>C | non_coding_transcript_exon_variant | 0.68 | streptomycin | Uncertain significance |
kanamycin | Not assoc w R | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.64 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.57 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473292 | n.1447_1449delGGAinsTGGG | non_coding_transcript_exon_variant | 0.58 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.56 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473315 | n.1470T>C | non_coding_transcript_exon_variant | 0.56 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.32 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474281 | n.624A>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1474292 | n.636_649delTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1474316 | n.659T>C | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1474348 | n.691C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474351 | n.694G>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474354 | n.697C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474450 | n.793T>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474454 | n.797G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474467 | n.810A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1474488 | n.831G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474498 | n.841G>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1474505 | n.848C>G | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474529 | n.872A>C | non_coding_transcript_exon_variant | 0.55 | capreomycin | |
linezolid | ||||||
rrl | 1474530 | n.873G>A | non_coding_transcript_exon_variant | 0.55 | capreomycin | |
linezolid | ||||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474539 | n.882C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1474540 | n.883T>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474634 | n.977T>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474663 | n.1006C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474676 | n.1019T>A | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474677 | n.1020A>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474692 | n.1035G>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474710 | n.1053_1054delTGinsGTGAA | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1474715 | n.1061delA | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474736 | n.1079C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474751 | n.1094G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474777 | n.1120T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474779 | n.1122G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474780 | n.1123C>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474782 | n.1125G>A | non_coding_transcript_exon_variant | 0.54 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474783 | n.1126G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1474790 | n.1133C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474827 | n.1170C>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474905 | n.1248T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475722 | n.2065G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1475747 | n.2090A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475752 | n.2095C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475756 | n.2101dupA | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2108A>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1475768 | n.2112dupT | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475781 | n.2124T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475788 | n.2131C>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475869 | n.2212C>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475883 | n.2226A>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475892 | n.2235A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475916 | n.2259C>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475937 | n.2280A>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475943 | n.2286G>A | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475945 | n.2288C>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475952 | n.2295A>G | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475963 | n.2306G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475970 | n.2313C>T | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475978 | n.2321C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1475998 | n.2341C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1476001 | n.2344T>C | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476164 | n.2507A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476165 | n.2508T>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476250 | n.2593C>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476255 | n.2598A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476256 | n.2599A>G | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.63 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476294 | n.2637_2643delACCCCCGinsGGTAC | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1476308 | n.2651G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476309 | n.2652G>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476312 | n.2655T>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476337 | n.2680C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.76 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476429 | n.2772A>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.54 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476515 | n.2858C>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476524 | n.2867C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476538 | n.2881A>G | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833921 | p.Lys127Thr | missense_variant | 0.34 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833955 | c.414G>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833961 | c.420C>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833994 | c.453G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833997 | c.456G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834285 | c.744G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834294 | c.753G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834298 | p.Gln253Glu | missense_variant | 0.4 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834307 | c.766_768delGACinsCG | frameshift_variant&missense_variant | 0.38 | pyrazinamide | Uncertain significance |
rpsA | 1834310 | c.769_771delGAGinsAA | frameshift_variant&missense_variant | 0.25 | pyrazinamide | Uncertain significance |
rpsA | 1834327 | c.786G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834354 | c.813G>T | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834361 | c.820T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834395 | p.Arg285Gln | missense_variant | 0.26 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.28 | pyrazinamide | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612813 | p.Thr102Ala | missense_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
mtrB | 3626562 | p.Pro18Ser | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040009 | c.696C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.26 | pyrazinamide | |
embC | 4241022 | p.Ala387Val | missense_variant | 0.96 | ethambutol | Uncertain significance |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4243190 | c.-43G>C | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
embA | 4243460 | c.228C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
aftB | 4267647 | p.Asp397Gly | missense_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407620 | p.Tyr195His | missense_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407927 | p.Glu92Asp | missense_variant | 1.0 | streptomycin | Not assoc w R |