TB-Profiler result

Run: ERR245675
Summary

Run ID: ERR245675

Sample name:

Date: 31-03-2023 18:14:12

Number of reads: 10657231

Percentage reads mapped: 74.7

Strain: lineage1.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1 Indo-Oceanic EAI RD239 0.99
lineage1.1 Indo-Oceanic EAI3;EAI4;EAI5;EAI6 RD239 1.0
lineage1.1.2 Indo-Oceanic EAI3;EAI5 RD239 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 0.99
gyrB 6124 c.885C>T synonymous_variant 0.99
gyrA 6775 c.-527G>C upstream_gene_variant 0.13
gyrA 6793 c.-509T>C upstream_gene_variant 0.19
gyrB 6797 p.Gly520Ser missense_variant 0.18
gyrA 6823 c.-479G>C upstream_gene_variant 0.21
gyrA 6844 c.-458T>G upstream_gene_variant 0.12
gyrA 7078 c.-224A>G upstream_gene_variant 0.12
gyrA 7093 c.-209T>C upstream_gene_variant 0.13
gyrA 7100 c.-202T>C upstream_gene_variant 0.14
gyrA 7123 c.-179C>G upstream_gene_variant 0.14
gyrA 7186 c.-116C>G upstream_gene_variant 0.13
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7391 c.90C>T synonymous_variant 0.15
gyrA 7394 c.93T>C synonymous_variant 0.15
gyrA 7493 c.192C>T synonymous_variant 0.19
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 0.99
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491310 c.528C>G synonymous_variant 0.13
fgd1 491316 c.534C>G synonymous_variant 0.3
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575821 c.474G>C synonymous_variant 0.15
mshA 575842 c.495G>C synonymous_variant 0.17
mshA 575851 c.504C>G synonymous_variant 0.15
mshA 575860 c.513G>A synonymous_variant 0.13
ccsA 620748 c.858T>G synonymous_variant 0.26
rpoB 760181 c.375T>C synonymous_variant 0.17
rpoB 760184 c.378A>G synonymous_variant 0.17
rpoB 760196 c.390C>G synonymous_variant 0.14
rpoB 760199 c.393C>G synonymous_variant 0.14
rpoB 760235 c.429T>C synonymous_variant 0.12
rpoB 760244 c.438G>C synonymous_variant 0.14
rpoB 760253 c.447T>C synonymous_variant 0.14
rpoB 760361 c.555T>C synonymous_variant 0.13
rpoB 760376 p.Asp190Glu missense_variant 0.22
rpoB 760406 c.600G>C synonymous_variant 0.21
rpoB 760407 p.Ser201Gly missense_variant 0.2
rpoB 760415 c.609C>T synonymous_variant 0.19
rpoB 760424 c.618C>G synonymous_variant 0.19
rpoB 760430 c.624T>C synonymous_variant 0.21
rpoB 760460 c.654G>C synonymous_variant 0.15
rpoB 760646 c.840C>G synonymous_variant 0.13
rpoB 760661 c.855A>C synonymous_variant 0.12
rpoB 760674 c.868T>C synonymous_variant 0.13
rpoB 760679 c.873A>G synonymous_variant 0.13
rpoB 760683 c.877T>C synonymous_variant 0.14
rpoB 761615 c.1809A>C synonymous_variant 0.12
rpoB 761969 c.2163G>A synonymous_variant 0.17
rpoB 761999 c.2193G>C synonymous_variant 0.2
rpoB 762002 c.2196C>G synonymous_variant 0.2
rpoB 762008 c.2202C>T synonymous_variant 0.19
rpoB 762158 c.2352G>C synonymous_variant 0.12
rpoB 762167 c.2361T>C synonymous_variant 0.14
rpoB 762179 c.2373C>T synonymous_variant 0.14
rpoB 762185 c.2379G>C synonymous_variant 0.14
rpoB 762249 p.Leu815Val missense_variant 0.2
rpoC 762836 c.-534C>G upstream_gene_variant 0.24
rpoC 762839 c.-531G>A upstream_gene_variant 0.16
rpoC 762857 c.-513C>G upstream_gene_variant 0.14
rpoC 762863 c.-507T>C upstream_gene_variant 0.15
rpoB 762879 p.Met1025Leu missense_variant 0.19
rpoC 762923 c.-447C>G upstream_gene_variant 0.19
rpoC 762929 c.-441G>T upstream_gene_variant 0.2
rpoC 762959 c.-411G>C upstream_gene_variant 0.16
rpoC 762962 c.-408C>T upstream_gene_variant 0.15
rpoC 762983 c.-387C>T upstream_gene_variant 0.14
rpoC 762995 c.-375G>C upstream_gene_variant 0.15
rpoC 763028 c.-342T>C upstream_gene_variant 0.14
rpoC 763031 c.-339T>C upstream_gene_variant 0.99
rpoC 763040 c.-330C>G upstream_gene_variant 0.12
rpoC 763053 c.-317T>C upstream_gene_variant 0.14
rpoC 763058 c.-312C>G upstream_gene_variant 0.13
rpoC 763076 c.-294C>G upstream_gene_variant 0.13
rpoC 763103 c.-267G>C upstream_gene_variant 0.12
rpoC 763115 c.-255T>C upstream_gene_variant 0.14
rpoC 763486 c.117T>C synonymous_variant 0.13
rpoC 763495 c.126G>A synonymous_variant 0.16
rpoC 763528 c.159G>A synonymous_variant 0.2
rpoC 763546 c.177A>G synonymous_variant 0.19
rpoC 763558 c.189C>T synonymous_variant 0.17
rpoC 763570 c.201G>C synonymous_variant 0.18
rpoC 763573 c.204G>C synonymous_variant 0.2
rpoC 763594 c.225C>T synonymous_variant 0.21
rpoC 763633 c.264T>C synonymous_variant 0.13
rpoC 763636 c.267T>C synonymous_variant 0.14
rpoC 763660 c.291T>G synonymous_variant 0.17
rpoC 763675 c.306C>G synonymous_variant 0.14
rpoC 763702 c.333C>G synonymous_variant 0.15
rpoC 763709 c.340C>T synonymous_variant 0.14
rpoC 763714 c.345G>C synonymous_variant 0.13
rpoC 763717 c.348T>C synonymous_variant 0.13
rpoC 763723 c.354G>C synonymous_variant 0.14
rpoC 763741 c.372C>T synonymous_variant 0.16
rpoC 763744 c.375G>C synonymous_variant 0.16
rpoC 763765 c.396T>G synonymous_variant 0.16
rpoC 763774 c.405G>C synonymous_variant 0.15
rpoC 763781 p.Ser138Ala missense_variant 0.12
rpoC 763884 p.Ala172Val missense_variant 0.9
rpoC 763886 c.517C>A synonymous_variant 0.9
rpoC 764353 c.984G>T synonymous_variant 0.14
rpoC 764521 c.1152T>C synonymous_variant 0.17
rpoC 764527 c.1158C>T synonymous_variant 0.15
rpoC 764530 c.1161C>T synonymous_variant 0.14
rpoC 764539 c.1170C>G synonymous_variant 0.23
rpoC 764548 c.1179G>T synonymous_variant 0.21
rpoC 764575 c.1206T>G synonymous_variant 0.17
rpoC 764584 c.1215G>A synonymous_variant 0.16
rpoC 764605 c.1236G>C synonymous_variant 0.13
rpoC 764611 c.1242G>T synonymous_variant 0.14
rpoC 764626 c.1257C>T synonymous_variant 0.14
rpoC 764632 c.1263T>C synonymous_variant 0.15
rpoC 764650 c.1281G>T synonymous_variant 0.18
rpoC 764662 c.1293G>C synonymous_variant 0.15
rpoC 764719 c.1350G>A synonymous_variant 0.18
rpoC 764725 p.Phe452Leu missense_variant 0.16
rpoC 764746 c.1377G>T synonymous_variant 0.24
rpoC 764752 c.1383G>C synonymous_variant 0.25
rpoC 764758 c.1389C>G synonymous_variant 0.27
rpoC 764764 c.1395T>C synonymous_variant 0.25
rpoC 764791 c.1422C>G synonymous_variant 0.19
rpoC 764803 c.1434C>T synonymous_variant 0.16
rpoC 764809 c.1440C>T synonymous_variant 0.14
rpoC 764812 c.1443C>G synonymous_variant 0.13
rpoC 764815 c.1446A>G synonymous_variant 0.12
rpoC 765171 p.Pro601Leu missense_variant 1.0
rpoC 765419 p.Val684Ile missense_variant 0.14
rpoC 765425 p.Lys686Glu missense_variant 0.13
rpoC 765466 c.2097C>T synonymous_variant 0.13
rpoC 765988 c.2619G>A synonymous_variant 0.98
rpoC 766345 c.2976T>C synonymous_variant 0.14
rpoC 766348 c.2979A>G synonymous_variant 0.13
rpoC 766357 c.2988C>T synonymous_variant 0.13
rpoC 766363 c.2994G>C synonymous_variant 0.13
rpoC 766369 c.3000C>G synonymous_variant 0.13
rpoC 766384 c.3015A>G synonymous_variant 0.12
rpoC 766393 c.3024C>G synonymous_variant 0.13
rpoC 766423 c.3054T>C synonymous_variant 0.14
rpoC 766426 c.3057C>T synonymous_variant 0.13
rpoC 766429 c.3060C>G synonymous_variant 0.13
rpoC 766459 c.3090G>C synonymous_variant 0.14
rpoC 766594 c.3225G>C synonymous_variant 0.12
rpoC 766607 p.Ile1080Leu missense_variant 0.14
rpoC 766750 c.3381C>G synonymous_variant 0.12
rpoC 766753 c.3384C>T synonymous_variant 0.13
rpoC 766765 c.3396A>C synonymous_variant 0.16
rpoC 766774 c.3405T>C synonymous_variant 0.17
rpoC 766776 p.Arg1136His missense_variant 0.18
rpoC 766798 c.3429C>G synonymous_variant 0.2
rpoC 766804 c.3435A>G synonymous_variant 0.19
rpoC 766807 c.3438T>C synonymous_variant 0.19
rpoC 766837 c.3468G>C synonymous_variant 0.14
rpoC 766843 c.3474T>C synonymous_variant 0.12
rpoC 766996 c.3627C>T synonymous_variant 0.14
rpoC 767008 c.3639G>A synonymous_variant 0.15
rpoC 767020 c.3651C>G synonymous_variant 0.19
rpoC 767023 c.3654C>T synonymous_variant 0.21
rpoC 767119 c.3750A>G synonymous_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781655 c.96T>C synonymous_variant 0.13
rpsL 781658 c.99A>G synonymous_variant 0.13
rpsL 781682 c.123T>C synonymous_variant 0.13
rpsL 781766 c.207C>T synonymous_variant 0.13
rpsL 781811 c.252C>T synonymous_variant 0.19
rpsL 781817 c.258G>T synonymous_variant 0.17
rpsL 781829 c.270G>C synonymous_variant 0.13
rpsL 781832 c.273T>C synonymous_variant 0.13
rpsL 781841 c.282C>T synonymous_variant 0.14
fbiC 1303587 c.657G>C synonymous_variant 0.16
fbiC 1303596 c.666G>C synonymous_variant 0.16
fbiC 1303602 c.672A>G synonymous_variant 0.17
fbiC 1303608 c.678G>A synonymous_variant 0.16
fbiC 1303614 c.684C>G synonymous_variant 0.15
fbiC 1303617 c.687C>G synonymous_variant 0.14
fbiC 1304544 c.1614T>C synonymous_variant 0.13
fbiC 1304553 c.1623C>T synonymous_variant 0.13
fbiC 1304559 p.Glu543Asp missense_variant 0.13
fbiC 1304562 c.1632G>C synonymous_variant 0.13
fbiC 1304565 c.1635C>G synonymous_variant 0.12
fbiC 1304568 c.1638T>C synonymous_variant 0.13
fbiC 1304580 c.1650T>C synonymous_variant 0.14
fbiC 1304946 c.2016G>C synonymous_variant 0.14
fbiC 1304958 c.2028T>G synonymous_variant 0.12
embR 1417019 p.Cys110Tyr missense_variant 1.0
embR 1417233 c.115C>T synonymous_variant 0.19
atpE 1461071 c.27C>G synonymous_variant 0.14
atpE 1461080 c.36C>T synonymous_variant 0.17
atpE 1461113 c.69C>T synonymous_variant 0.14
atpE 1461116 c.72C>G synonymous_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.21
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.21
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.2
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.21
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.2
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.32
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.36
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.15
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.4
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.24
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.14
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.13
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.13
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.12
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.13
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.13
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.14
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.15
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.41
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.39
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.37
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.35
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.23
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.2
rrs 1473343 n.1498G>T non_coding_transcript_exon_variant 0.17
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.18
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.18
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.23
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.23
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.19
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.14
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.24
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.24
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.24
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.25
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.25
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.27
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.31
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.33
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.3
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.29
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.29
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.29
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.2
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.28
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.32
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.21
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.35
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.35
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.37
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.36
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.14
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.13
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.12
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.12
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.12
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.12
rrl 1474708 n.1052_1053insACAAG non_coding_transcript_exon_variant 0.13
rrl 1474711 n.1055_1058delGTGT non_coding_transcript_exon_variant 0.13
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.12
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.14
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.32
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.32
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.35
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.34
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.32
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.24
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 0.19
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.17
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.16
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.15
rrl 1475220 n.1563G>C non_coding_transcript_exon_variant 0.14
rrl 1475363 n.1706C>A non_coding_transcript_exon_variant 0.15
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.13
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.28
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.38
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.37
rrl 1475482 n.1825A>G non_coding_transcript_exon_variant 0.38
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.39
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.33
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.31
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.21
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.38
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.29
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.29
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.28
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.29
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.33
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.48
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.4
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 0.4
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.42
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.41
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.41
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.41
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.39
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.37
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.4
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.38
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.34
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.35
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.35
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.36
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.4
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.44
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.47
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.47
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.51
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.55
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.54
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.54
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.52
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.49
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.5
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.46
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.49
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.4
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.4
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.38
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.36
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.37
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.37
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.33
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.29
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.29
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.29
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.28
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.23
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.19
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.13
fabG1 1673546 p.Ala36Gly missense_variant 0.25
inhA 1674656 p.Ser152Thr missense_variant 0.13
inhA 1674660 c.459G>C synonymous_variant 0.14
inhA 1674687 c.486G>C synonymous_variant 0.13
inhA 1674819 c.618G>T synonymous_variant 0.17
inhA 1674825 c.624C>T synonymous_variant 0.16
inhA 1674828 p.Glu209Asp missense_variant 0.16
inhA 1674837 c.636C>T synonymous_variant 0.17
inhA 1674840 c.639C>G synonymous_variant 0.16
inhA 1674846 p.Ile215Met missense_variant 0.16
inhA 1674858 c.657G>A synonymous_variant 0.14
inhA 1674876 c.675C>G synonymous_variant 0.16
inhA 1674879 c.678T>G synonymous_variant 0.16
inhA 1674883 p.Ile228Leu missense_variant 0.17
inhA 1674892 p.Asn231Asp missense_variant 0.2
inhA 1674904 p.Ala235Pro missense_variant 0.19
inhA 1674915 c.714C>G synonymous_variant 0.12
rpsA 1833727 c.186G>C synonymous_variant 0.16
rpsA 1833733 c.192C>T synonymous_variant 0.16
rpsA 1833734 p.Ala65Ser missense_variant 0.17
rpsA 1833742 c.201A>G synonymous_variant 0.19
rpsA 1833745 c.204G>C synonymous_variant 0.19
rpsA 1833772 c.231C>T synonymous_variant 0.17
rpsA 1833778 c.237C>T synonymous_variant 0.16
rpsA 1833781 c.240T>G synonymous_variant 0.15
rpsA 1833790 c.249T>C synonymous_variant 0.14
rpsA 1833799 c.258C>G synonymous_variant 0.11
rpsA 1833859 c.318C>T synonymous_variant 0.12
rpsA 1833874 c.333T>C synonymous_variant 0.14
rpsA 1833892 c.351G>A synonymous_variant 0.16
rpsA 1833894 p.Ala118Glu missense_variant 0.16
rpsA 1833904 c.363G>A synonymous_variant 0.2
rpsA 1833907 c.366G>A synonymous_variant 0.21
rpsA 1833928 c.387G>C synonymous_variant 0.26
rpsA 1833949 c.408T>C synonymous_variant 0.26
rpsA 1833970 c.429G>C synonymous_variant 0.21
rpsA 1833979 c.438T>C synonymous_variant 0.15
rpsA 1834021 c.480C>T synonymous_variant 0.12
rpsA 1834030 c.489C>G synonymous_variant 0.18
rpsA 1834069 c.528G>C synonymous_variant 0.23
rpsA 1834096 c.555G>C synonymous_variant 0.18
rpsA 1834099 c.558C>G synonymous_variant 0.17
rpsA 1834102 c.561T>C synonymous_variant 0.15
rpsA 1834108 c.567C>G synonymous_variant 0.15
rpsA 1834192 c.651C>G synonymous_variant 0.13
rpsA 1834234 c.693G>C synonymous_variant 0.19
rpsA 1834240 c.699T>C synonymous_variant 0.2
rpsA 1834249 c.708T>C synonymous_variant 0.17
rpsA 1834261 c.720A>G synonymous_variant 0.13
rpsA 1834264 c.723G>C synonymous_variant 0.13
rpsA 1834348 c.807T>C synonymous_variant 0.13
rpsA 1834357 c.816T>G synonymous_variant 0.17
rpsA 1834361 c.820T>C synonymous_variant 0.19
rpsA 1834366 c.825A>G synonymous_variant 0.2
rpsA 1834387 c.846C>T synonymous_variant 0.22
rpsA 1834396 c.855G>C synonymous_variant 0.21
rpsA 1834408 c.867C>T synonymous_variant 0.22
rpsA 1834411 c.870T>C synonymous_variant 0.22
rpsA 1834423 c.882G>C synonymous_variant 0.2
rpsA 1834451 c.910T>C synonymous_variant 0.17
rpsA 1834456 c.915T>G synonymous_variant 0.16
rpsA 1834468 c.927A>G synonymous_variant 0.15
rpsA 1834483 c.942G>A synonymous_variant 0.14
rpsA 1834489 c.948T>C synonymous_variant 0.13
rpsA 1834603 c.1062G>A synonymous_variant 0.16
rpsA 1834606 c.1065C>T synonymous_variant 0.16
rpsA 1834609 c.1068T>C synonymous_variant 0.16
rpsA 1834619 c.1078T>C synonymous_variant 0.2
rpsA 1834633 c.1092A>G synonymous_variant 0.2
rpsA 1834639 c.1098T>C synonymous_variant 0.19
rpsA 1834678 c.1137C>G synonymous_variant 0.14
rpsA 1834690 c.1149T>C synonymous_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2167983 p.Gly877Asp missense_variant 1.0
PPE35 2169866 c.747G>C synonymous_variant 0.24
Rv1979c 2222308 p.Asp286Gly missense_variant 0.99
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2517941 c.-174C>G upstream_gene_variant 0.12
kasA 2517953 c.-162C>T upstream_gene_variant 0.13
kasA 2518132 c.18C>T synonymous_variant 1.0
eis 2714366 p.Val323Leu missense_variant 0.17
eis 2715586 c.-254G>C upstream_gene_variant 0.23
ahpC 2725954 c.-239C>T upstream_gene_variant 0.25
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
ahpC 2726468 c.276G>A synonymous_variant 1.0
ahpC 2726756 c.564C>G synonymous_variant 0.23
folC 2746186 c.1413G>C synonymous_variant 0.21
pepQ 2859680 p.Leu247Val missense_variant 0.2
pepQ 2859974 p.Ala149Pro missense_variant 0.17
Rv2752c 3064632 c.1560C>T synonymous_variant 0.98
Rv2752c 3064741 p.Gly484Ala missense_variant 0.3
thyX 3067355 c.591A>G synonymous_variant 0.12
thyX 3067364 c.582C>T synonymous_variant 0.13
thyX 3067385 c.561C>G synonymous_variant 0.13
thyX 3067491 p.Ala152Val missense_variant 0.99
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448714 p.Asp71His missense_variant 1.0
Rv3083 3449058 p.Ser185Arg missense_variant 0.22
Rv3083 3449673 p.Tyr390* stop_gained 0.2
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475023 c.1017G>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
fprA 3475280 p.Val425Gly missense_variant 0.25
fbiA 3640446 c.-97A>T upstream_gene_variant 1.0
fbiB 3641955 p.Gly141Arg missense_variant 0.22
fbiB 3642734 c.1200G>C synonymous_variant 0.25
rpoA 3877656 c.852T>G synonymous_variant 0.14
rpoA 3877662 c.846C>T synonymous_variant 0.14
rpoA 3877668 c.840A>G synonymous_variant 0.12
rpoA 3877818 c.690A>G synonymous_variant 0.17
rpoA 3877824 c.684G>A synonymous_variant 0.17
rpoA 3877839 c.669G>C synonymous_variant 0.14
rpoA 3877842 c.666A>G synonymous_variant 0.14
rpoA 3877848 c.660C>T synonymous_variant 0.13
rpoA 3877905 c.603A>C synonymous_variant 0.12
rpoA 3877908 c.600T>C synonymous_variant 0.12
rpoA 3877920 c.588G>C synonymous_variant 0.14
rpoA 3877926 c.582G>C synonymous_variant 0.17
rpoA 3877962 c.546G>T synonymous_variant 0.12
rpoA 3878143 p.Gly122Asp missense_variant 0.12
rpoA 3878160 c.348C>G synonymous_variant 0.15
rpoA 3878163 c.345C>T synonymous_variant 0.17
rpoA 3878187 c.321C>G synonymous_variant 0.19
rpoA 3878193 c.315T>C synonymous_variant 0.17
rpoA 3878202 c.306G>C synonymous_variant 0.16
rpoA 3878217 c.291A>G synonymous_variant 0.15
clpC1 4038551 c.2154C>G synonymous_variant 0.14
clpC1 4038596 c.2109A>G synonymous_variant 0.19
clpC1 4038623 c.2082A>G synonymous_variant 0.12
clpC1 4038755 c.1950G>C synonymous_variant 0.13
clpC1 4038767 c.1938G>C synonymous_variant 0.15
clpC1 4038782 c.1923G>C synonymous_variant 0.14
clpC1 4038791 c.1914G>C synonymous_variant 0.14
clpC1 4038812 c.1893T>C synonymous_variant 0.12
clpC1 4038815 c.1890G>C synonymous_variant 0.12
clpC1 4038974 c.1731T>C synonymous_variant 0.11
clpC1 4038989 c.1716T>C synonymous_variant 0.14
clpC1 4038997 c.1708T>C synonymous_variant 0.17
clpC1 4039010 c.1695G>A synonymous_variant 0.17
clpC1 4039022 c.1683A>G synonymous_variant 0.15
clpC1 4039145 c.1560G>C synonymous_variant 0.13
clpC1 4039169 p.Glu512Asp missense_variant 0.16
clpC1 4039172 c.1533A>G synonymous_variant 0.15
clpC1 4039178 c.1527G>C synonymous_variant 0.17
clpC1 4039183 c.1522T>C synonymous_variant 0.17
clpC1 4039193 c.1512C>G synonymous_variant 0.16
clpC1 4039199 p.Ala502Glu missense_variant 0.14
clpC1 4039208 c.1497C>G synonymous_variant 0.15
clpC1 4039220 c.1485G>C synonymous_variant 0.15
clpC1 4039241 c.1464G>C synonymous_variant 0.17
clpC1 4039262 c.1443C>T synonymous_variant 0.12
clpC1 4039361 c.1344C>G synonymous_variant 0.14
clpC1 4039382 c.1323C>G synonymous_variant 0.25
clpC1 4039391 c.1314T>G synonymous_variant 0.22
clpC1 4039397 c.1308A>G synonymous_variant 0.25
clpC1 4039409 c.1296T>C synonymous_variant 0.18
clpC1 4039412 c.1293T>G synonymous_variant 0.17
clpC1 4039415 p.Glu430Asp missense_variant 0.16
clpC1 4039430 c.1275T>C synonymous_variant 0.15
clpC1 4039442 c.1263A>G synonymous_variant 0.13
clpC1 4039454 c.1251A>T synonymous_variant 0.13
clpC1 4039481 c.1224T>C synonymous_variant 0.14
clpC1 4039484 c.1221T>C synonymous_variant 0.15
clpC1 4039487 c.1218G>C synonymous_variant 0.14
clpC1 4039508 c.1197G>C synonymous_variant 0.15
clpC1 4039517 c.1188C>G synonymous_variant 0.14
clpC1 4039556 c.1149G>C synonymous_variant 0.12
clpC1 4039589 c.1116G>C synonymous_variant 0.13
clpC1 4039592 c.1113G>C synonymous_variant 0.14
clpC1 4039616 c.1089G>C synonymous_variant 0.17
clpC1 4039622 c.1083C>T synonymous_variant 0.16
clpC1 4039649 c.1056G>C synonymous_variant 0.15
clpC1 4039652 c.1053G>C synonymous_variant 0.15
clpC1 4039661 c.1044T>C synonymous_variant 0.14
clpC1 4039694 c.1011G>C synonymous_variant 0.17
clpC1 4039724 c.981A>G synonymous_variant 0.17
clpC1 4039733 c.972G>C synonymous_variant 0.16
clpC1 4039751 c.954A>G synonymous_variant 0.14
clpC1 4039865 c.840T>C synonymous_variant 0.14
clpC1 4039898 c.807C>G synonymous_variant 0.23
clpC1 4039931 p.Gly258Val missense_variant 0.2
clpC1 4039937 c.768G>C synonymous_variant 0.17
clpC1 4039946 c.759A>T synonymous_variant 0.16
clpC1 4039952 c.753T>C synonymous_variant 0.14
clpC1 4039955 c.750G>C synonymous_variant 0.13
clpC1 4039958 c.747G>C synonymous_variant 0.13
clpC1 4039979 c.726C>G synonymous_variant 0.17
clpC1 4039988 c.717C>G synonymous_variant 0.18
clpC1 4040009 c.696C>G synonymous_variant 0.16
clpC1 4040018 c.687G>C synonymous_variant 0.16
clpC1 4040021 c.684A>C synonymous_variant 0.15
clpC1 4040024 c.681A>G synonymous_variant 0.16
clpC1 4040033 c.672G>C synonymous_variant 0.14
clpC1 4040517 p.Val63Ala missense_variant 0.92
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4240789 c.927T>C synonymous_variant 0.13
embC 4240819 c.957A>G synonymous_variant 0.12
embC 4241042 p.Asn394Asp missense_variant 1.0
embC 4241056 c.1194C>G synonymous_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.37
embC 4242827 p.Leu989Val missense_variant 0.21
embA 4243848 p.Val206Met missense_variant 1.0
embA 4244375 c.1143C>G synonymous_variant 0.24
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
ubiA 4269529 p.Ala102Gly missense_variant 0.16
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4326851 p.Ser208Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 0.99
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0