TB-Profiler result

Run: ERR4816113
Summary

Run ID: ERR4816113

Sample name:

Date: 2025-09-15T14:46:06.589888

Number of reads: 1374700

Percentage reads mapped: 69.45

Median coverage: 45.0

Strain: lineage4.1.1.1

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 100.0
lineage4.1 Euro-American None 100.0
lineage4.1.1 Euro-American (X-type) None 100.0
lineage4.1.1.1 Euro-American (X-type) RD183 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 6610 c.-692C>G upstream_gene_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6613 c.-689A>G upstream_gene_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6616 c.-686A>G upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6631 c.-671C>T upstream_gene_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6637 c.-665T>G upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6640 c.-662A>T upstream_gene_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6643 c.-659A>G upstream_gene_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6649 c.-653T>C upstream_gene_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6655 c.-647T>C upstream_gene_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6670 c.-632G>C upstream_gene_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6673 c.-629A>C upstream_gene_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6676 c.-626T>G upstream_gene_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6697 c.1458C>T synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6703 c.-599G>T upstream_gene_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6706 c.-596G>A upstream_gene_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6709 c.-593A>G upstream_gene_variant 0.28 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6715 c.1476C>T synonymous_variant 0.27 levofloxacin Uncertain significance
moxifloxacin Not assoc w R - Interim
gyrA 6727 c.-575G>T upstream_gene_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.25 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6745 c.1506T>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6764 c.-538C>T upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6772 c.1533C>G synonymous_variant 0.14 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6775 c.-527G>T upstream_gene_variant 0.13 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6796 c.-506C>T upstream_gene_variant 0.13 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6798 p.Gly520Ala missense_variant 0.13 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 7051 p.Glu604Asp missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7066 c.-236G>C upstream_gene_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7072 c.-230G>A upstream_gene_variant 0.27 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7078 c.-224A>T upstream_gene_variant 0.28 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7084 c.-218A>G upstream_gene_variant 0.3 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7090 c.-212C>T upstream_gene_variant 0.29 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7093 c.1854T>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.3 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7100 c.1861T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7120 c.-182T>C upstream_gene_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7123 c.-179C>G upstream_gene_variant 0.33 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7126 c.1887G>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7129 c.-173T>G upstream_gene_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7136 c.-166T>C upstream_gene_variant 0.35 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7144 c.-158A>G upstream_gene_variant 0.3 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7150 c.-152G>A upstream_gene_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7153 c.1914G>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7159 c.1920C>T synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7162 c.-140C>G upstream_gene_variant 0.3 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7168 c.-134C>G upstream_gene_variant 0.3 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7178 c.-124T>C upstream_gene_variant 0.28 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7186 c.1947C>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7189 c.-113C>T upstream_gene_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7412 c.111C>G synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7421 c.120G>C synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7427 c.126G>C synonymous_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7430 c.129G>A synonymous_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7442 c.141G>C synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7457 c.156T>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7463 c.162G>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7466 c.165G>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7469 c.168C>T synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7472 c.171T>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 7475 c.174A>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7484 c.183T>C synonymous_variant 0.25 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7490 c.189C>G synonymous_variant 0.25 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7496 c.195C>G synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7523 c.222C>G synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>A synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7571 c.270G>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7574 c.273G>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8915 c.1614A>G synonymous_variant 0.14 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8945 c.1644G>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Lys missense_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8990 c.1689C>G synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8993 c.1692C>T synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8998 p.Leu566Trp missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9018 p.Gln573Lys missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>T synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9026 c.1725G>C synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9029 c.1728T>C synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9032 c.1731T>C synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9035 c.1734G>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 9044 c.1743C>G synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 490661 c.-122_-121insGCGAGC upstream_gene_variant 0.98 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
Rv0565c 657269 p.Ser68Pro missense_variant 1.0 ethionamide Uncertain significance
nusG 734452 p.Glu67Gln missense_variant 0.13 rifampicin Uncertain significance
nusG 734460 c.207G>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 0.18 rifampicin Uncertain significance
rpoB 760276 p.Lys157Met missense_variant 0.19 rifampicin Uncertain significance
rpoB 760283 c.477G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760313 c.507G>C synonymous_variant 0.13 rifampicin Uncertain significance
rpoB 760319 p.Ser171Arg missense_variant 0.12 rifampicin Uncertain significance
rpoB 760328 c.522G>C synonymous_variant 0.12 rifampicin Uncertain significance
rpoB 760331 c.525G>T synonymous_variant 0.12 rifampicin Uncertain significance
rpoB 760370 c.564C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760376 p.Asp190Glu missense_variant 0.14 rifampicin Uncertain significance
rpoB 760382 c.576G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760484 c.678A>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760502 c.696C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760511 c.705G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 760522 p.Ser239Asn missense_variant 0.17 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760541 c.735G>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760561 c.757_758delCG frameshift_variant 0.15 rifampicin Uncertain significance
rpoB 760567 c.761delCinsGGG frameshift_variant&missense_variant 0.15 rifampicin Uncertain significance
rpoB 760571 c.765G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760588 p.Thr261Ile missense_variant 0.18 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.18 rifampicin Uncertain significance
rpoB 760595 c.789C>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 760596 p.Thr264Pro missense_variant 0.19 rifampicin Uncertain significance
rpoB 760607 c.801G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 760611 c.805T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760668 p.Thr288Ala missense_variant 0.16 rifampicin Uncertain significance
rpoB 760674 c.868T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760858 p.Val351Ala missense_variant 0.24 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Leu missense_variant 0.22 rifampicin Uncertain significance
rpoB 760877 c.1071G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 760883 c.1077G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 760887 p.Thr361Val missense_variant 0.22 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.29 rifampicin Uncertain significance
rpoB 760928 c.1122G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.32 rifampicin Uncertain significance
rpoB 760973 c.1167G>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 761015 c.1209G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 761102 c.1296A>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 761126 c.1320G>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761159 c.1353G>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 761165 c.1359G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761666 c.1860G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761669 c.1863C>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 761675 c.1869G>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761687 c.1881C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761690 c.1884G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761693 c.1887G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 761717 c.1911C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 761720 c.1914_1916delCGAinsGG frameshift_variant&synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761727 p.Ser641Gly missense_variant 0.15 rifampicin Uncertain significance
rpoB 761728 c.1923dupC frameshift_variant 0.15 rifampicin Uncertain significance
rpoB 761732 c.1926C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761741 c.1935G>A synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761750 c.1944G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761930 c.2124G>C synonymous_variant 0.13 rifampicin Uncertain significance
rpoB 761933 c.2127G>C synonymous_variant 0.12 rifampicin Uncertain significance
rpoB 761948 c.2142G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761955 p.Ile717Val missense_variant 0.18 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 762101 c.2295C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.11 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 762911 c.-459C>T upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoB 762917 c.3111C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoB 762989 c.3183G>A synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763034 c.-336C>A upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoB 763040 c.3234C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.12 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 763702 c.333C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 763711 c.342G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 763714 c.345G>A synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 763717 c.348T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763732 c.363C>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763741 c.372C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763747 c.378G>A synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763765 c.396T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763768 c.399C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763774 c.405G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763781 p.Ser138Ala missense_variant 0.14 rifampicin Uncertain significance
rpoC 763792 p.Glu141Asp missense_variant 0.14 rifampicin Uncertain significance
rpoC 763796 p.Met143Leu missense_variant 0.13 rifampicin Uncertain significance
rpoC 763801 c.432C>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 763807 c.438T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 764458 c.1089G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764506 c.1137C>T synonymous_variant 0.32 rifampicin Uncertain significance
rpoC 764527 c.1158C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>A synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.35 rifampicin Uncertain significance
rpoC 764554 c.1185C>T synonymous_variant 0.39 rifampicin Uncertain significance
rpoC 764566 c.1197C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.4 rifampicin Uncertain significance
rpoC 764593 c.1224C>T synonymous_variant 0.4 rifampicin Uncertain significance
rpoC 764602 c.1233C>T synonymous_variant 0.37 rifampicin Uncertain significance
rpoC 764611 c.1242G>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>T synonymous_variant 0.37 rifampicin Uncertain significance
rpoC 764650 c.1281G>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764810 p.Pro481Ala missense_variant 0.22 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764887 c.1518G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764912 p.Met515Gln missense_variant 0.12 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765150 p.Gly594Glu missense_variant 1.0 rifampicin Not assoc w R
rpoC 765478 c.2109T>G synonymous_variant 0.12 rifampicin Uncertain significance
rpoC 765861 p.Phe831Tyr missense_variant 0.16 rifampicin Uncertain significance
rpoC 765868 c.2499G>A synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 765871 c.2502T>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.19 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 765907 c.2538G>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 765947 c.2578T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCTT synonymous_variant 0.31 rifampicin Uncertain significance
rpoC 765973 c.2604C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 766594 c.3225G>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 767080 c.3711G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767125 c.3756G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767128 c.3759C>T synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 767134 c.3765C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>T synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 767180 p.Ala1271Ser missense_variant 0.29 rifampicin Uncertain significance
rpoC 767188 c.3819G>A synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 767206 c.3837C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 767221 c.3852C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>T synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 767233 c.3864T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Ser missense_variant 0.16 rifampicin Uncertain significance
rpoC 767267 p.Ala1300Asn missense_variant 0.17 rifampicin Uncertain significance
rpoC 767281 c.3912C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 0.97 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781682 c.123T>C synonymous_variant 0.13 streptomycin Uncertain significance
rpsL 781802 c.243G>C synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781808 c.249C>T synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781811 c.252C>T synonymous_variant 0.14 streptomycin Uncertain significance
rplC 800219 c.-590T>C upstream_gene_variant 1.0 linezolid Uncertain significance
fbiC 1303367 p.Thr146Ile missense_variant 1.0 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.28 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.28 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.46 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.5 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.5 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.67 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.67 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.65 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.65 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.67 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.7 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.79 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.79 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
streptomycin Uncertain significance
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.43 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.3 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.47 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.28 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.23 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.23 capreomycin Not assoc w R
linezolid Uncertain significance
rpsA 1833604 c.63C>T synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833616 c.75A>T synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833619 c.78A>C synonymous_variant 0.12 pyrazinamide Uncertain significance
rpsA 1833661 c.120A>G synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833664 c.123C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833676 c.135A>G synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833685 c.144G>C synonymous_variant 0.12 pyrazinamide Uncertain significance
rpsA 1833697 c.156C>T synonymous_variant 0.12 pyrazinamide Uncertain significance
rpsA 1833700 c.159C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833709 c.168C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833787 c.246C>G synonymous_variant 0.12 pyrazinamide Uncertain significance
rpsA 1833811 c.270G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833829 c.288A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1833832 c.291G>A synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1833838 c.297G>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1833841 c.300C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1833847 c.306C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833856 c.315A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833862 c.321G>T synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833874 c.333T>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833886 c.345C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833892 c.351G>A synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833894 p.Ala118Glu missense_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833928 c.387G>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1833949 c.408T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1833970 c.429G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1833979 c.438T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1833991 c.450C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834000 c.459G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834009 c.468C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834012 c.471G>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834015 c.474G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834021 c.480C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834030 c.489C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834033 c.492C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834097 p.Ser186Thr missense_variant 0.12 pyrazinamide Uncertain significance
rpsA 1834264 c.723G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1834297 c.756C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834303 c.762T>G synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834306 c.765T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834339 c.798C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834378 c.837T>C synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>T synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834405 c.864C>T synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834408 c.867C>T synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834411 c.870T>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834417 c.876G>C synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834423 c.882G>C synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834435 c.894G>C synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834451 c.910T>C synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>G synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1834480 c.939C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834483 c.942G>A synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834489 c.948T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834498 c.957C>T synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834520 p.Ala327Ser missense_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1834543 c.1002C>G synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1834552 c.1011G>T synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834555 c.1014T>G synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834557 p.Ala339Gly missense_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1834609 c.1068T>C synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1834612 c.1071G>C synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1834619 c.1078T>C synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1834633 c.1092A>G synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1834639 c.1098T>C synonymous_variant 0.33 pyrazinamide Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
eis 2715349 c.-17T>C upstream_gene_variant 1.0 amikacin Uncertain significance
kanamycin Uncertain significance
ahpC 2726210 c.18T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
Rv2477c 2783317 c.726G>C synonymous_variant 0.12 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783341 c.702C>G synonymous_variant 0.12 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783350 c.693T>C synonymous_variant 0.13 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783353 c.690T>C synonymous_variant 0.13 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783356 c.687C>G synonymous_variant 0.13 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783362 c.681G>C synonymous_variant 0.14 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783371 c.672A>G synonymous_variant 0.14 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783374 c.669G>C synonymous_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783377 c.666C>G synonymous_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783425 c.618C>G synonymous_variant 0.14 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783440 c.603T>C synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783449 c.594C>T synonymous_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrA 3627056 c.294C>T synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3627068 c.282T>C synonymous_variant 0.17 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627083 c.-470G>T upstream_gene_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3627098 c.252A>C synonymous_variant 0.14 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.18 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627110 c.-497G>C upstream_gene_variant 0.18 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3627119 c.231T>G synonymous_variant 0.15 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3627133 p.Ala73Ser missense_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627134 c.-521C>T upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627139 c.-526T>C upstream_gene_variant 0.18 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627149 c.-536G>A upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
fbiA 3641447 p.Thr302Met missense_variant 1.0 clofazimine Not assoc w R
delamanid Uncertain significance
pretomanid Uncertain significance
rpoA 3877553 p.Glu319Lys missense_variant 0.97 rifampicin Not assoc w R
rpoA 3877587 c.921A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877596 c.912G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877602 c.906C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877656 c.852T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3877665 c.843C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3877677 c.831G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3877686 c.822A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877983 c.525C>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877989 c.519A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878070 c.438T>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoA 3878079 c.429C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878102 p.Val136Ile missense_variant 0.22 rifampicin Uncertain significance
rpoA 3878103 c.405A>G synonymous_variant 0.25 rifampicin Uncertain significance
rpoA 3878118 c.390T>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoA 3878127 c.381G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoA 3878130 c.378C>G synonymous_variant 0.25 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.26 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878175 c.333G>T synonymous_variant 0.33 rifampicin Uncertain significance
rpoA 3878184 c.324C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878259 c.249G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3878274 c.234G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878283 p.Glu75Asp missense_variant 0.24 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.2 rifampicin Uncertain significance
clpC1 4038767 c.1938G>T synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038770 c.1935C>A synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038773 c.1932T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038782 c.1923G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038790 c.1915C>T synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038812 c.1893T>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038818 c.1887G>A synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038847 p.Ser620Thr missense_variant 0.12 pyrazinamide Uncertain significance
clpC1 4038860 c.1845G>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039238 c.1467C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039292 c.1413C>T synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039316 p.Glu463Asp missense_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039319 c.1386T>A synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039322 c.1383T>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039328 c.1377A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039336 c.1369C>T synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039338 p.Thr456Gln missense_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039346 p.Arg453Ser missense_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039360 p.Ser449Arg missense_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039361 c.1344C>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039391 c.1314T>C synonymous_variant 0.32 pyrazinamide Uncertain significance
clpC1 4039397 c.1308A>G synonymous_variant 0.34 pyrazinamide Uncertain significance
clpC1 4039409 c.1296T>C synonymous_variant 0.37 pyrazinamide Uncertain significance
clpC1 4039412 c.1293T>G synonymous_variant 0.37 pyrazinamide Uncertain significance
clpC1 4039415 p.Glu430Asp missense_variant 0.37 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4039442 c.1263A>G synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039451 c.1254G>A synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039454 c.1251A>T synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039457 c.1248C>T synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039463 c.1242C>G synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039466 c.1239T>C synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039469 c.1236T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039472 c.1233G>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039478 c.1227G>C synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039481 c.1224T>C synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039484 c.1221T>A synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039487 c.1218G>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039517 c.1188C>G synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039522 c.1183C>T synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039541 c.1164C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039694 c.1011G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039724 c.981A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039733 c.972G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039739 c.966C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039745 c.960C>T synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4039751 c.954A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039757 c.948A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039769 c.936C>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039775 c.930G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039778 c.927A>G synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039826 c.879C>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039831 c.874T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039850 c.855T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039865 c.840T>C synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039874 c.831C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039904 c.801A>G synonymous_variant 0.33 pyrazinamide Uncertain significance
clpC1 4039907 c.798G>A synonymous_variant 0.32 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039934 c.771G>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039943 c.762G>C synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039946 c.759A>G synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039949 c.756G>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039952 c.753T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039958 c.747G>C synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039964 c.741C>G synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039975 p.Asp244Asn missense_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039979 c.726C>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039982 c.723G>A synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4040000 c.705C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4040021 c.684A>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4040033 c.672G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4040042 c.663C>T synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4040087 c.618G>T synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040093 c.612C>G synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040510 c.195G>A synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4040522 c.183T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040534 c.171A>G synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040540 c.165G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040543 c.162C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040546 c.159G>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040551 c.154T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040573 c.132T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040579 c.126A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040582 c.123G>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040588 c.117T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040591 c.114C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040597 c.108C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040603 c.102T>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040606 c.99T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
embC 4240897 c.1035C>G synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242803 p.Val981Leu missense_variant 1.0 ethambutol Not assoc w R
embB 4249408 c.2895G>A synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338498 p.Glu8Asp missense_variant 0.98 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance