TB-Profiler result

Run: ERR2513470
Summary

Run ID: ERR2513470

Sample name:

Date: 2024-04-16T09:34:04.771338

Number of reads: 2763595

Percentage reads mapped: 81.08

Median coverage: 77.0

Strain: lineage4.2.2.2

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.2.2 Euro-American (Ural) None 1.0
lineage4.2 Euro-American None 0.94
La1.2.BCG M.bovis None 0.06
lineage4 Euro-American None 0.98
lineage4.2.2.2 Euro-American (Ural) None 0.98
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 708 c.708T>C synonymous_variant 0.16 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.2 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.21 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.19 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.16 isoniazid
dnaA 759 c.759C>T synonymous_variant 0.17 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.19 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.16 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.15 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.17 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.15 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.15 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 0.16 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.19 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.17 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.16 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.16 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.16 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.17 isoniazid Not assoc w R - Interim
gyrB 6196 c.957C>T synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.2 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.16 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.31 levofloxacin Uncertain significance
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.24 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.19 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7015 c.-287G>A upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>A upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.23 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.23 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>C upstream_gene_variant 0.17 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.15 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.16 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7457 c.156T>C synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.16 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7658 c.357A>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7670 c.369A>G synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.19 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8276 c.975G>A synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.18 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>A synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318_1320delTTGinsCA frameshift_variant&missense_variant 0.16 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8688 p.Ala463Ser missense_variant 0.92 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8891 c.1590G>A synonymous_variant 0.14 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 0.15 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9252 p.Val651Ile missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9284 c.1983T>C synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 9300 p.Ala667Ser missense_variant 0.16 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.17 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.16 levofloxacin
moxifloxacin
fgd1 490797 c.15G>A synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.16 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 0.24 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fgd1 491130 c.348C>G synonymous_variant 0.15 clofazimine
pretomanid
delamanid
mshA 575737 c.390T>C synonymous_variant 0.15 ethionamide
isoniazid
mshA 575770 c.423G>A synonymous_variant 0.18 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.17 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.18 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.18 ethionamide
isoniazid
mshA 575809 c.462C>T synonymous_variant 0.23 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.2 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.2 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.2 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.19 ethionamide
isoniazid
mshA 575833 c.486C>G synonymous_variant 0.19 ethionamide
isoniazid
mshA 575845 c.498C>T synonymous_variant 0.17 ethionamide
isoniazid Not assoc w R - Interim
mshA 576077 c.730C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R
ccsA 619584 c.-307A>T upstream_gene_variant 0.16 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.16 capreomycin
amikacin
kanamycin
ccsA 620226 c.336G>A synonymous_variant 0.18 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.18 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 0.16 capreomycin
amikacin
kanamycin
ccsA 620265 c.375C>G synonymous_variant 0.18 capreomycin
amikacin
kanamycin
ccsA 620268 c.378G>C synonymous_variant 0.19 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 620284 c.394_396delGCGinsCC frameshift_variant&missense_variant 0.2 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.2 capreomycin
amikacin
kanamycin
ccsA 620298 c.408G>C synonymous_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 620310 c.420C>T synonymous_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.26 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.23 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.19 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.18 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.16 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
Rv0565c 657425 p.Gly16Ser missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.15 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.15 ethionamide
hadA 731717 c.-213T>G upstream_gene_variant 0.18 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.21 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.23 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.16 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.16 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.19 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.19 isoniazid
nusG 734442 c.189G>A synonymous_variant 0.16 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.17 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.17 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.19 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.16 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.2 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.2 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.23 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.23 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.21 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.2 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.21 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.21 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.19 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.17 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.16 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.19 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.24 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.16 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.2 rifampicin
rpoB 760718 c.912C>T synonymous_variant 0.18 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760949 c.1143C>T synonymous_variant 0.16 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.24 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.24 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.22 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.23 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.22 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.23 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761489 c.1683G>A synonymous_variant 0.87 rifampicin Not assoc w R
rpoB 761510 c.1704T>C synonymous_variant 0.16 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.2 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.18 rifampicin
rpoB 761773 p.His656Pro missense_variant 0.15 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.16 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.16 rifampicin
rpoB 761815 p.Ala670Asp missense_variant 0.15 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.19 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.2 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.18 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.17 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.17 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.22 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.21 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.23 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.23 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.23 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.21 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.24 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.24 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.22 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.22 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.21 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.19 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.22 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.19 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.16 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.16 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.16 rifampicin
rpoB 763040 c.3234C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.18 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.21 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.15 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.18 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.21 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.26 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.18 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.19 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.19 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.2 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.19 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.2 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.21 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.24 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.19 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.2 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.2 rifampicin
rpoC 763936 c.567C>G synonymous_variant 0.18 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.18 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764005 c.636G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.17 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.16 rifampicin
rpoC 764041 p.Ser224Arg missense_variant 0.15 rifampicin
rpoC 764215 c.846A>G synonymous_variant 0.18 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.2 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.19 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.19 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.2 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.29 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.19 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.18 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.19 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.18 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.22 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.22 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.17 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.16 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.23 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.21 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.19 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.23 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.25 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.25 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.26 rifampicin Not assoc w R
rpoC 765019 c.1650A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.21 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.17 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.16 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.19 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.18 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.26 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.24 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.2 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.2 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.2 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.17 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.23 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.21 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.2 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.16 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.15 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.2 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.2 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.27 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.21 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.26 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.25 rifampicin
rpoC 766030 c.2661C>G synonymous_variant 0.25 rifampicin
rpoC 766036 c.2667C>T synonymous_variant 0.25 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.24 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.22 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.2 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.19 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.21 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.16 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>T synonymous_variant 0.17 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.17 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.17 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.19 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.22 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.18 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.15 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.16 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.16 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.18 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.18 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.18 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.18 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.17 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.16 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.14 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.17 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.2 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.18 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.15 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.18 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.18 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.27 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.29 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.38 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.35 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.33 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.39 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.43 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.35 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.28 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.26 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.26 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.23 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.22 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.23 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776402 c.2079C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781628 c.69T>C synonymous_variant 0.16 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.18 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.22 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.23 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.27 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.27 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.25 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.23 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.24 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.23 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.21 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.23 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.23 streptomycin
rpsL 781763 c.204C>A synonymous_variant 0.21 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.22 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.21 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.2 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.19 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.2 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.2 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.16 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.15 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.15 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.15 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.16 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.16 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.16 streptomycin Uncertain significance
rplC 800204 c.-605T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.19 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.18 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.18 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.16 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.17 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.17 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.17 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.15 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.15 linezolid
rplC 801246 c.438C>T synonymous_variant 0.16 linezolid
rplC 801249 c.441T>C synonymous_variant 0.16 linezolid
rplC 801255 c.447C>T synonymous_variant 0.16 linezolid
rplC 801264 c.456C>T synonymous_variant 0.15 linezolid
rplC 801300 c.492C>G synonymous_variant 0.19 linezolid
rplC 801309 c.501C>G synonymous_variant 0.18 linezolid
rplC 801312 c.504G>C synonymous_variant 0.17 linezolid
rplC 801321 c.513C>T synonymous_variant 0.16 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.16 linezolid
rplC 801341 p.Leu178His missense_variant 0.14 linezolid
rplC 801348 c.540T>G synonymous_variant 0.15 linezolid
rplC 801357 c.549T>C synonymous_variant 0.16 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.16 linezolid
fbiC 1303818 c.888C>G synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1304040 c.1110C>G synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fbiC 1304046 c.1116C>G synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>C synonymous_variant 0.15 clofazimine
pretomanid
delamanid
fbiC 1304058 c.1128G>A synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fbiC 1304059 c.1129C>T synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>T synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>C synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Asp missense_variant 0.15 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.17 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.15 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.15 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.27 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1304891 p.Ile654Thr missense_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.22 clofazimine
pretomanid
delamanid
atpE 1461113 c.69C>T synonymous_variant 0.18 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.17 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.16 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.16 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.15 bedaquiline Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.32 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.33 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.5 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.36 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.28 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1476717 n.3060C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
inhA 1674780 c.579T>G synonymous_variant 0.16 ethionamide
isoniazid
inhA 1674789 c.588G>T synonymous_variant 0.16 ethionamide
isoniazid
inhA 1674795 c.594G>C synonymous_variant 0.15 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.15 ethionamide
isoniazid
inhA 1674813 c.612C>T synonymous_variant 0.15 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 0.16 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674819 c.618G>A synonymous_variant 0.16 ethionamide
isoniazid
inhA 1674828 p.Glu209Asp missense_variant 0.18 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.19 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.16 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.16 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.16 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 0.17 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 0.16 ethionamide
isoniazid
rpsA 1833568 c.27G>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.17 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.19 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.18 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.19 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.18 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.18 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.18 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.18 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.2 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.2 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.15 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.15 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.17 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.17 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.17 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.21 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.2 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.2 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.24 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.2 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.18 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.16 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.17 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.19 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.17 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.18 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.15 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.16 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.16 pyrazinamide
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2063685 c.1044G>A synonymous_variant 1.0 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin Not assoc w R
amikacin Not assoc w R
bacA 2063911 p.Ile273Thr missense_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
bacA 2064972 c.-244T>C upstream_gene_variant 0.18 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
katG 2155695 c.417C>G synonymous_variant 0.16 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.2 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.16 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.16 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.16 isoniazid
katG 2155743 c.369G>C synonymous_variant 0.16 isoniazid
katG 2155746 c.366C>T synonymous_variant 0.16 isoniazid
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
kasA 2517950 c.-165C>G upstream_gene_variant 0.3 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.2 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.2 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.15 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.18 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.18 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.17 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.19 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.19 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.18 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.16 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.16 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.16 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.14 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.16 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.15 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.15 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.15 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.16 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.18 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.17 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.17 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.16 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.16 isoniazid
folC 2747302 c.297A>C synonymous_variant 0.15 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.16 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.16 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.22 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.2 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 0.22 para-aminosalicylic_acid
Rv2477c 2782928 p.Thr372Lys missense_variant 0.14 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Not assoc w R
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Not assoc w R
amikacin Uncertain significance
Rv2477c 2782936 c.1107G>T synonymous_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.19 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.19 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>A synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783048 p.Asp332Gly missense_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783062 c.981C>T synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.18 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.17 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.21 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.23 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.24 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.22 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.2 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.19 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2752c 3066280 c.-89C>T upstream_gene_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067439 c.507A>G synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.22 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.23 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.21 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.21 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.17 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 0.18 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.16 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.16 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.15 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.15 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.17 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.15 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.16 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.16 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.16 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.19 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.19 para-aminosalicylic_acid
ald 3086742 c.-78A>C upstream_gene_variant 1.0 cycloserine
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625543 c.-633G>C upstream_gene_variant 0.15 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.2 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.18 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.19 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.21 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.2 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.19 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.19 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrB 3625633 c.981C>T synonymous_variant 0.2 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625636 c.978C>G synonymous_variant 0.2 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.17 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.18 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.15 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.15 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.15 bedaquiline
rifampicin
mtrB 3625797 p.Val273Met missense_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626876 c.-263A>G upstream_gene_variant 0.16 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.18 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.18 bedaquiline
rifampicin
mtrB 3626900 c.-287G>A upstream_gene_variant 0.21 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.22 bedaquiline
rifampicin
mtrB 3626912 c.-299T>G upstream_gene_variant 0.21 bedaquiline
rifampicin
mtrB 3626927 c.-314G>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.23 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.22 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.22 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.23 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 0.19 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 0.25 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.27 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.26 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.27 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.28 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.3 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 0.25 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.25 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.25 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.26 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.24 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.23 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.14 bedaquiline
rifampicin
fbiB 3642587 p.Met351Ile missense_variant 0.15 clofazimine
pretomanid
delamanid
fbiB 3642593 c.1059G>T synonymous_variant 0.15 clofazimine
pretomanid
delamanid
fbiB 3642614 c.1080C>T synonymous_variant 0.15 clofazimine
pretomanid
delamanid
fbiB 3642617 c.1083C>G synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 0.16 clofazimine
pretomanid
delamanid
rpoA 3877587 c.921A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.22 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.19 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.18 rifampicin
rpoA 3877692 c.816G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 0.16 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.31 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.33 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.31 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.3 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.35 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.35 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.35 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 0.34 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.34 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.27 rifampicin
rpoA 3877986 c.522G>C synonymous_variant 0.22 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.16 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.15 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.18 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.23 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.2 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.2 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.19 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.21 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.22 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.23 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.25 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.25 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.25 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.25 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.22 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.24 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.25 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.25 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.23 rifampicin
rpoA 3878463 c.45C>A synonymous_variant 0.17 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.16 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.16 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.16 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.17 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.18 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.18 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.2 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.16 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.16 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 0.16 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.15 rifampicin Uncertain significance
rpoA 3878932 c.-425G>A upstream_gene_variant 0.18 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.2 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.18 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.21 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.2 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.19 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.16 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.15 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.15 rifampicin
clpC1 4038456 p.Val750Glu missense_variant 0.17 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.17 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.17 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.17 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.17 pyrazinamide
clpC1 4038497 p.Ser736Gln missense_variant 0.17 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.19 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.22 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.2 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.14 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.15 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.19 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.17 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.18 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.18 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.19 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.18 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.18 pyrazinamide
clpC1 4038749 c.1956C>A synonymous_variant 0.21 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.21 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.21 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.21 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.19 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.18 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.2 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.23 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.23 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.2 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.21 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.22 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.21 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.21 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.19 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.19 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.18 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.21 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.21 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.26 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.25 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.22 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.23 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.21 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.21 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039229 c.1476C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.17 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039338 p.Thr456Gln missense_variant 0.14 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.17 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.17 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.17 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.16 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.17 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.17 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.21 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.2 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.19 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.2 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.19 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4039988 c.717C>G synonymous_variant 0.18 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.19 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.25 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.24 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.26 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.18 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.18 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.19 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.19 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.16 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.15 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.15 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.14 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.14 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.17 pyrazinamide
panD 4044746 c.-467_-465delGTGinsAC upstream_gene_variant 0.19 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.18 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.17 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.15 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.16 pyrazinamide
panD 4044819 c.-538C>A upstream_gene_variant 0.15 pyrazinamide
panD 4044833 c.-552A>G upstream_gene_variant 0.18 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.19 pyrazinamide
panD 4044848 c.-567T>A upstream_gene_variant 0.19 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 0.18 pyrazinamide
panD 4044860 c.-579C>G upstream_gene_variant 0.16 pyrazinamide
panD 4044872 c.-591C>G upstream_gene_variant 0.17 pyrazinamide
panD 4044890 c.-609G>C upstream_gene_variant 0.16 pyrazinamide
panD 4044954 c.-674_-673delCCinsAT upstream_gene_variant 0.16 pyrazinamide
glpK 4138460 c.1296C>T synonymous_variant 0.14 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>T synonymous_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138496 c.1260G>T synonymous_variant 0.14 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 0.16 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>G synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139541 p.Ile72Thr missense_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139554 p.Ala68Ser missense_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139561 c.195G>A synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139581 p.Asn59Asp missense_variant 0.17 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139597 c.159C>G synonymous_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139601 p.Arg52Gln missense_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240669 c.807G>C synonymous_variant 0.21 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.21 ethambutol Not assoc w R
embC 4240677 p.Gly272Ala missense_variant 0.19 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.19 ethambutol
embC 4240693 c.831T>G synonymous_variant 0.16 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.18 ethambutol Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.22 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.23 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.22 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.2 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.18 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.18 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.15 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.15 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.17 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.21 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.18 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.15 ethambutol
embC 4241218 c.1356G>C synonymous_variant 0.15 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4245146 c.1914G>A synonymous_variant 0.16 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.16 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.16 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.19 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.18 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.16 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.16 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.16 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.17 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.19 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.19 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.21 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.19 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.2 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.18 ethambutol
embB 4247603 c.1090C>T synonymous_variant 0.15 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.16 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.14 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.16 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.18 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.17 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.18 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.18 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 0.18 ethambutol
embB 4247830 c.1317A>C synonymous_variant 0.19 ethambutol
embB 4247836 c.1323A>G synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.22 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.24 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.23 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.24 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embB 4247899 p.Met462Ile missense_variant 0.22 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.18 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.2 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.16 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.15 ethambutol Not assoc w R - Interim
embB 4248130 c.1617G>C synonymous_variant 0.16 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.16 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.16 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.16 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.16 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.16 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.16 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.15 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.15 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.16 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.16 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.19 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.15 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.19 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.18 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.18 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.16 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin