TB-Profiler result

Run: ERR9786592
Summary

Run ID: ERR9786592

Sample name:

Date: 2025-09-15T15:39:31.635823

Number of reads: 2126929

Percentage reads mapped: 81.05

Median coverage: 99.0

Strain: lineage4.3.4.2

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 100.0
lineage4.3 Euro-American (LAM) None 100.0
lineage4.3.4 Euro-American (LAM) RD174 100.0
lineage4.3.4.2 Euro-American (LAM) RD174 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6817 c.1578G>A synonymous_variant 0.99 levofloxacin Not assoc w R
moxifloxacin Not assoc w R - Interim
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7631 c.330G>C synonymous_variant 0.13 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8729 c.1428T>C synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8731 p.Gly477Ala missense_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8747 c.1446A>G synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8750 c.1449C>G synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8756 c.1455A>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8774 c.1473C>T synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8786 c.1485T>C synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8796 p.Ile499Val missense_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8799 p.Ala500Pro missense_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8810 c.1509A>C synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8840 c.1539C>G synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8843 c.1542G>A synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8909 c.1608C>T synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8915 c.1614A>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8952 p.Gln551Ala missense_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8967 p.Ala556Asn missense_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8987 c.1686C>G synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8990 c.1689C>G synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8996 c.1695T>C synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8998 p.Leu566Trp missense_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13418 c.141G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
fgd1 491133 c.351A>C synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491138 p.Glu119Ala missense_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491142 c.360C>G synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491144 p.Ala121Asp missense_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491166 c.384G>C synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
rpoB 760196 c.390C>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760316 c.510C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760325 c.519G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760334 c.528G>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760340 c.534G>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.17 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.18 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 0.23 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760484 c.678A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760511 c.705G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760514 c.708C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.16 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.16 rifampicin Uncertain significance
rpoB 760541 c.735G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.16 rifampicin Uncertain significance
rpoB 760567 p.Ser254Trp missense_variant 0.16 rifampicin Uncertain significance
rpoB 760568 c.762_763insGC frameshift_variant 0.16 rifampicin Uncertain significance
rpoB 760571 c.765G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760585 p.Asn260Ser missense_variant 0.17 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.17 rifampicin Uncertain significance
rpoB 760595 c.789C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760596 p.Thr264Pro missense_variant 0.17 rifampicin Uncertain significance
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 760634 c.828T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760658 c.852G>A synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760661 c.855A>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760674 c.868T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760883 c.1077G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760887 p.Thr361Val missense_variant 0.15 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760925 c.1119T>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760928 c.1122G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760934 c.1128C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760946 c.1140A>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760949 c.1143C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760965 p.Met387Leu missense_variant 0.16 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760982 c.1176G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 761102 c.1296A>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 761126 c.1320G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761217 p.Pro471Ala missense_variant 0.22 rifampicin Uncertain significance
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 761234 c.1428G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761765 c.1959T>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 762245 c.2439G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762275 c.2469C>A synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 762284 c.2478G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 762329 c.2523G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 0.13 rifampicin Uncertain significance
rpoB 762369 c.2563T>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 762374 c.-996G>C upstream_gene_variant 0.14 rifampicin Uncertain significance
rpoC 762380 c.-990T>C upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoC 762395 c.-975G>C upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoC 762398 c.-972T>C upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoB 762404 c.2598T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoB 762416 c.2610A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoC 762443 c.-927G>C upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoB 762449 c.2643C>A synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.24 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoB 763115 c.3309T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.15 rifampicin Uncertain significance
rpoB 763136 c.3330C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoC 763528 c.159G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 763675 c.306C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 763702 c.333C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763714 c.345G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 763741 c.372C>T synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 763747 c.378G>A synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763765 c.396T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763783 c.414G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 763792 p.Glu141Asp missense_variant 0.16 rifampicin Uncertain significance
rpoC 763807 c.438T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763831 c.462A>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 763837 c.468G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 763840 c.471G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763900 c.531G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 763924 c.555G>A synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 764344 c.975C>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 764353 c.984G>T synonymous_variant 0.12 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 764446 c.1077T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764449 c.1080G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764452 c.1083T>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 764458 c.1089G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764491 c.1122G>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764497 c.1128A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764521 c.1152T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765871 c.2502T>C synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.13 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 765934 c.2565C>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 765937 c.2568T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 765947 c.2578T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 765961 c.2592G>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 765964 p.Leu865Phe missense_variant 0.13 rifampicin Uncertain significance
rpoC 765967 c.2598C>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.12 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.14 rifampicin Uncertain significance
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781929 p.Gly124Ser missense_variant 0.13 streptomycin Uncertain significance
fbiC 1304544 c.1614T>C synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304547 c.1617C>G synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304559 p.Glu543Asp missense_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304562 c.1632G>C synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304565 c.1635C>G synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304568 c.1638T>C synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304571 c.1641G>C synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304580 c.1650T>C synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304682 c.1752C>T synonymous_variant 0.12 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.21 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.26 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.27 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.3 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.25 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.25 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.23 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.2 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.16 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.2 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.2 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.28 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.28 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.26 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.26 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.26 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.13 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.13 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.26 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373_2378delACCTCGinsGCTCAC non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.29 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.2 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.2 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
inhA 1674477 c.276G>T synonymous_variant 0.13 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674486 c.285T>C synonymous_variant 0.14 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674503 p.Thr101Ser missense_variant 0.14 ethionamide Uncertain significance
isoniazid Uncertain significance
rpsA 1834162 c.621A>G synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834213 c.672G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834234 c.693G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834240 c.699T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834243 c.702G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834249 c.708T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834261 c.720A>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834279 c.738C>T synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834303 c.762T>G synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834306 c.765T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834330 c.789C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834345 c.804C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834366 c.825A>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834396 c.855G>T synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834411 c.870T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834423 c.882G>T synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834432 c.891G>T synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834451 c.910T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>G synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834513 c.972C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834520 p.Ala327Ser missense_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834540 c.999G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834543 c.1002C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2156815 c.-704A>G upstream_gene_variant 1.0 isoniazid Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
eis 2714432 p.Val301Ile missense_variant 1.0 amikacin Uncertain significance
kanamycin Uncertain significance
thyA 3073868 p.Thr202Ala missense_variant 0.99 para-aminosalicylic_acid Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0 pyrazinamide Not assoc w R
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
rpoA 3877803 c.705G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877818 c.690A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877866 c.642G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3877875 c.633T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877893 c.615C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3877929 c.579C>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.19 rifampicin Uncertain significance
rpoA 3877974 c.534G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877989 c.519A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877992 c.516C>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3877998 c.510G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3878001 c.505_507delTCAinsAGC synonymous_variant 0.2 rifampicin Uncertain significance
rpoA 3878019 c.489A>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3878022 c.486T>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3878025 c.483C>T synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3878028 c.480G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878031 c.477T>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3878034 c.474A>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878046 c.462T>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoA 3878050 p.Arg153Lys missense_variant 0.22 rifampicin Uncertain significance
rpoA 3878055 c.453A>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3878061 c.447G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878070 c.438T>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3878079 c.429C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3878103 c.405A>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3878106 c.402G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3878118 c.390T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3878124 c.384G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3878127 c.381G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.16 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878154 c.354G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.17 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3878244 c.264G>A synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3878247 c.261G>C synonymous_variant 0.14 rifampicin Uncertain significance
clpC1 4038287 c.2418C>T synonymous_variant 1.0 pyrazinamide Not assoc w R
clpC1 4038941 c.1764G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038953 c.1752A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038956 c.1749T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038965 c.1740T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038971 c.1734T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038974 c.1731T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038997 c.1708T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039067 c.1638G>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039079 c.1626C>G synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039091 c.1614G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039097 c.1608G>T synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039100 c.1605C>T synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4039103 c.1602T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039106 c.1599G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039136 c.1569C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039142 c.1563A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039145 c.1560G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039169 c.1536A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039178 c.1527G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039183 c.1522T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039187 c.1518G>T synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039190 c.1515C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039199 c.1506C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039241 c.1464G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039274 c.1431G>A synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039277 c.1428C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039280 c.1425G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039286 c.1419T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039292 c.1413C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039295 c.1410A>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039310 c.1395A>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039313 c.1392C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039321 p.Ala462Ser missense_variant 0.12 pyrazinamide Uncertain significance
clpC1 4039338 p.Thr456Gln missense_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039346 c.1359G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039352 c.1353C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039361 c.1344C>A synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039517 c.1188C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039553 c.1152C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039559 c.1146C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039570 p.Met379Leu missense_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039577 c.1128T>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039592 c.1113G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039598 c.1107C>T synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4039610 c.1095G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039622 c.1083C>T synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039649 c.1056G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039652 c.1053G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039664 c.1041G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039670 c.1035G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039682 c.1023C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039694 c.1011G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039724 c.981A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039733 c.972G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039742 c.963C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039748 c.957G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039751 c.954A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039757 c.948A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039760 c.945T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039769 c.936C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039778 c.927A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039793 c.912C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039802 c.903G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039817 c.888A>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039820 c.885T>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039829 p.Leu292Phe missense_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039832 c.873C>G synonymous_variant 0.12 pyrazinamide Uncertain significance
clpC1 4039844 c.861C>T synonymous_variant 0.13 pyrazinamide Not assoc w R - Interim
clpC1 4039850 c.855T>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039865 c.840T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039898 c.807C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039904 c.801A>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039913 c.792C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040126 c.579C>T synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4040144 c.561G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4040147 c.558A>G synonymous_variant 0.13 pyrazinamide Not assoc w R - Interim
clpC1 4040159 c.546G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040162 c.543G>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040168 c.537G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040171 c.534C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040177 c.528C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040195 c.510G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040200 c.505T>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040201 c.504C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040207 c.498T>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040213 p.Ser164Asn missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040219 c.486C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040225 c.480A>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040228 c.477G>A synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040231 c.474C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040237 c.468C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4040249 c.456A>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040258 c.447G>A synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040267 c.438A>G synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040279 c.426C>G synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040300 c.405C>T synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040306 c.399G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
embC 4239763 c.-100C>T upstream_gene_variant 0.99 ethambutol Not assoc w R
embC 4240382 p.Gly174Arg missense_variant 1.0 ethambutol Uncertain significance
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
gid 4408156 p.Leu16Arg missense_variant 1.0 streptomycin Not assoc w R