TB-Profiler result

Run: ERR9786592
Summary

Run ID: ERR9786592

Sample name:

Date: 02-04-2023 12:34:05

Number of reads: 2126929

Percentage reads mapped: 81.05

Strain: lineage4.3.4.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.2 Euro-American (LAM) LAM1;LAM4;LAM11 RD174 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6817 c.-485G>A upstream_gene_variant 0.99
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7631 c.330G>C synonymous_variant 0.13
gyrA 8729 c.1428T>C synonymous_variant 0.15
gyrA 8731 p.Gly477Ala missense_variant 0.15
gyrA 8747 c.1446A>G synonymous_variant 0.17
gyrA 8750 c.1449C>G synonymous_variant 0.17
gyrA 8756 c.1455A>G synonymous_variant 0.17
gyrA 8762 c.1461G>C synonymous_variant 0.17
gyrA 8765 p.Asp488Glu missense_variant 0.17
gyrA 8767 p.Arg489Lys missense_variant 0.18
gyrA 8774 c.1473C>T synonymous_variant 0.21
gyrA 8786 c.1485T>C synonymous_variant 0.19
gyrA 8796 p.Ile499Val missense_variant 0.19
gyrA 8799 p.Ala500Pro missense_variant 0.2
gyrA 8810 c.1509A>C synonymous_variant 0.19
gyrA 8828 c.1527T>C synonymous_variant 0.18
gyrA 8829 c.1528T>C synonymous_variant 0.18
gyrA 8840 c.1539C>G synonymous_variant 0.18
gyrA 8843 c.1542G>A synonymous_variant 0.18
gyrA 8852 c.1551T>G synonymous_variant 0.17
gyrA 8858 c.1557T>G synonymous_variant 0.19
gyrA 8867 c.1566A>G synonymous_variant 0.19
gyrA 8897 c.1596T>C synonymous_variant 0.17
gyrA 8903 c.1602T>C synonymous_variant 0.19
gyrA 8909 c.1608C>T synonymous_variant 0.19
gyrA 8915 c.1614A>G synonymous_variant 0.19
gyrA 8939 c.1638T>C synonymous_variant 0.17
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.15
gyrA 8952 p.Gln551Ala missense_variant 0.14
gyrA 8967 p.Ala556Asn missense_variant 0.14
gyrA 8987 c.1686C>G synonymous_variant 0.14
gyrA 8990 c.1689C>G synonymous_variant 0.14
gyrA 8996 c.1695T>C synonymous_variant 0.14
gyrA 8998 p.Leu566Trp missense_variant 0.14
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491133 c.351A>C synonymous_variant 0.14
fgd1 491138 p.Glu119Ala missense_variant 0.14
fgd1 491142 c.360C>G synonymous_variant 0.14
fgd1 491144 p.Ala121Asp missense_variant 0.14
fgd1 491166 c.384G>C synonymous_variant 0.13
rpoB 760196 c.390C>G synonymous_variant 0.13
rpoB 760235 c.429T>C synonymous_variant 0.14
rpoB 760244 c.438G>C synonymous_variant 0.14
rpoB 760298 c.492G>C synonymous_variant 0.16
rpoB 760310 c.504G>C synonymous_variant 0.15
rpoB 760316 c.510C>G synonymous_variant 0.16
rpoB 760325 c.519G>C synonymous_variant 0.16
rpoB 760331 c.525G>C synonymous_variant 0.16
rpoB 760334 c.528G>T synonymous_variant 0.16
rpoB 760340 c.534G>T synonymous_variant 0.17
rpoB 760357 p.Thr184Ser missense_variant 0.17
rpoB 760361 c.555T>C synonymous_variant 0.17
rpoB 760376 p.Asp190Glu missense_variant 0.18
rpoB 760406 c.600G>C synonymous_variant 0.23
rpoB 760407 p.Ser201Gly missense_variant 0.23
rpoB 760415 c.609C>T synonymous_variant 0.2
rpoB 760424 c.618C>G synonymous_variant 0.17
rpoB 760430 c.624T>C synonymous_variant 0.15
rpoB 760460 c.654G>C synonymous_variant 0.18
rpoB 760475 c.669A>G synonymous_variant 0.17
rpoB 760478 c.672C>T synonymous_variant 0.17
rpoB 760481 c.675G>T synonymous_variant 0.17
rpoB 760484 c.678A>G synonymous_variant 0.17
rpoB 760511 c.705G>C synonymous_variant 0.17
rpoB 760514 c.708C>T synonymous_variant 0.18
rpoB 760522 p.Ser239Asn missense_variant 0.16
rpoB 760532 c.726T>C synonymous_variant 0.16
rpoB 760533 p.Val243Thr missense_variant 0.16
rpoB 760541 c.735G>C synonymous_variant 0.19
rpoB 760561 c.757_758delCG frameshift_variant 0.16
rpoB 760567 p.Ser254Trp missense_variant 0.16
rpoB 760568 c.762_763insGC frameshift_variant 0.16
rpoB 760571 c.765G>C synonymous_variant 0.17
rpoB 760585 p.Asn260Ser missense_variant 0.17
rpoB 760591 p.Val262Ala missense_variant 0.17
rpoB 760595 c.789C>T synonymous_variant 0.17
rpoB 760596 p.Thr264Pro missense_variant 0.17
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 0.18
rpoB 760634 c.828T>C synonymous_variant 0.18
rpoB 760646 c.840C>G synonymous_variant 0.16
rpoB 760655 c.849A>G synonymous_variant 0.16
rpoB 760658 c.852G>A synonymous_variant 0.16
rpoB 760661 c.855A>C synonymous_variant 0.18
rpoB 760670 c.864G>C synonymous_variant 0.16
rpoB 760674 c.868T>C synonymous_variant 0.15
rpoB 760679 c.873A>G synonymous_variant 0.15
rpoB 760683 c.877T>C synonymous_variant 0.14
rpoB 760793 c.987A>G synonymous_variant 0.15
rpoB 760805 c.999G>C synonymous_variant 0.18
rpoB 760817 c.1011A>G synonymous_variant 0.14
rpoB 760820 c.1014T>C synonymous_variant 0.13
rpoB 760826 c.1020C>G synonymous_variant 0.14
rpoB 760830 c.1024T>C synonymous_variant 0.15
rpoB 760841 c.1035T>C synonymous_variant 0.17
rpoB 760859 c.1053T>C synonymous_variant 0.16
rpoB 760862 c.1056G>C synonymous_variant 0.16
rpoB 760877 c.1071G>C synonymous_variant 0.17
rpoB 760883 c.1077G>C synonymous_variant 0.17
rpoB 760886 c.1080A>G synonymous_variant 0.15
rpoB 760887 p.Thr361Val missense_variant 0.15
rpoB 760910 c.1104C>T synonymous_variant 0.16
rpoB 760916 c.1110C>T synonymous_variant 0.15
rpoB 760919 c.1113C>T synonymous_variant 0.14
rpoB 760925 c.1119T>C synonymous_variant 0.14
rpoB 760928 c.1122G>C synonymous_variant 0.14
rpoB 760931 c.1125C>G synonymous_variant 0.14
rpoB 760934 c.1128C>T synonymous_variant 0.14
rpoB 760946 c.1140A>G synonymous_variant 0.14
rpoB 760949 c.1143C>T synonymous_variant 0.14
rpoB 760965 p.Met387Leu missense_variant 0.16
rpoB 760970 c.1164G>C synonymous_variant 0.16
rpoB 760973 c.1167G>C synonymous_variant 0.16
rpoB 760982 c.1176G>C synonymous_variant 0.16
rpoB 760985 c.1179G>C synonymous_variant 0.16
rpoB 760988 c.1182C>G synonymous_variant 0.15
rpoB 760991 c.1185G>T synonymous_variant 0.16
rpoB 760997 c.1191G>C synonymous_variant 0.17
rpoB 761015 c.1209G>C synonymous_variant 0.16
rpoB 761027 c.1221A>G synonymous_variant 0.14
rpoB 761036 c.1230G>C synonymous_variant 0.15
rpoB 761037 c.1231T>C synonymous_variant 0.16
rpoB 761051 c.1245G>T synonymous_variant 0.18
rpoB 761054 c.1248G>C synonymous_variant 0.19
rpoB 761057 c.1251G>C synonymous_variant 0.18
rpoB 761060 c.1254C>G synonymous_variant 0.18
rpoB 761063 c.1257C>G synonymous_variant 0.2
rpoB 761084 c.1278C>T synonymous_variant 0.23
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.22
rpoB 761102 c.1296A>G synonymous_variant 0.23
rpoB 761126 c.1320G>T synonymous_variant 0.24
rpoB 761132 c.1326G>T synonymous_variant 0.24
rpoB 761133 c.1327T>C synonymous_variant 0.24
rpoB 761147 c.1341C>T synonymous_variant 0.23
rpoB 761150 c.1344A>C synonymous_variant 0.23
rpoB 761165 c.1359G>C synonymous_variant 0.24
rpoB 761180 c.1374A>C synonymous_variant 0.23
rpoB 761195 c.1389G>C synonymous_variant 0.24
rpoB 761198 c.1392G>T synonymous_variant 0.23
rpoB 761217 p.Pro471Ala missense_variant 0.22
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.22
rpoB 761234 c.1428G>C synonymous_variant 0.23
rpoB 761249 c.1443A>G synonymous_variant 0.24
rpoB 761261 c.1455G>T synonymous_variant 0.22
rpoB 761264 c.1458C>G synonymous_variant 0.21
rpoB 761300 c.1494G>C synonymous_variant 0.14
rpoB 761765 c.1959T>C synonymous_variant 0.14
rpoB 762245 c.2439G>C synonymous_variant 0.13
rpoB 762275 c.2469C>A synonymous_variant 0.16
rpoB 762284 c.2478G>C synonymous_variant 0.16
rpoB 762293 c.2487T>C synonymous_variant 0.16
rpoB 762314 c.2508C>T synonymous_variant 0.15
rpoB 762329 c.2523G>C synonymous_variant 0.13
rpoB 762362 p.Glu852Asp missense_variant 0.13
rpoB 762369 c.2563T>C synonymous_variant 0.14
rpoC 762374 c.-996G>C upstream_gene_variant 0.14
rpoC 762380 c.-990T>C upstream_gene_variant 0.16
rpoC 762395 c.-975G>C upstream_gene_variant 0.18
rpoC 762398 c.-972T>C upstream_gene_variant 0.18
rpoC 762404 c.-966T>C upstream_gene_variant 0.18
rpoC 762410 c.-960T>C upstream_gene_variant 0.19
rpoC 762416 c.-954A>G upstream_gene_variant 0.19
rpoC 762434 c.-936T>C upstream_gene_variant 0.18
rpoC 762443 c.-927G>C upstream_gene_variant 0.18
rpoC 762449 c.-921C>A upstream_gene_variant 0.18
rpoC 762452 c.-918G>C upstream_gene_variant 0.17
rpoC 762470 c.-900G>C upstream_gene_variant 0.18
rpoC 762929 c.-441G>T upstream_gene_variant 0.2
rpoC 762959 c.-411G>C upstream_gene_variant 0.25
rpoC 762962 c.-408C>T upstream_gene_variant 0.25
rpoC 762989 c.-381G>A upstream_gene_variant 0.23
rpoC 762995 c.-375G>T upstream_gene_variant 0.22
rpoC 763004 c.-366G>A upstream_gene_variant 0.21
rpoC 763007 c.-363C>T upstream_gene_variant 0.2
rpoC 763028 c.-342T>C upstream_gene_variant 0.23
rpoC 763031 c.-339T>C upstream_gene_variant 0.24
rpoC 763053 c.-317T>C upstream_gene_variant 0.23
rpoC 763070 c.-300T>C upstream_gene_variant 0.24
rpoC 763085 c.-285C>G upstream_gene_variant 0.22
rpoC 763103 c.-267G>C upstream_gene_variant 0.19
rpoC 763115 c.-255T>C upstream_gene_variant 0.2
rpoC 763127 c.-243G>C upstream_gene_variant 0.19
rpoC 763130 c.-240G>A upstream_gene_variant 0.15
rpoC 763133 c.-237G>C upstream_gene_variant 0.15
rpoC 763136 c.-234C>T upstream_gene_variant 0.15
rpoC 763142 c.-228C>G upstream_gene_variant 0.16
rpoC 763528 c.159G>A synonymous_variant 0.2
rpoC 763546 c.177A>G synonymous_variant 0.2
rpoC 763558 c.189C>T synonymous_variant 0.23
rpoC 763570 c.201G>C synonymous_variant 0.22
rpoC 763573 c.204G>C synonymous_variant 0.23
rpoC 763594 c.225C>T synonymous_variant 0.27
rpoC 763615 c.246G>C synonymous_variant 0.27
rpoC 763618 c.249C>T synonymous_variant 0.28
rpoC 763633 c.264T>C synonymous_variant 0.27
rpoC 763657 c.288G>A synonymous_variant 0.26
rpoC 763660 c.291T>G synonymous_variant 0.27
rpoC 763666 c.297G>A synonymous_variant 0.28
rpoC 763675 c.306C>G synonymous_variant 0.25
rpoC 763699 c.330G>T synonymous_variant 0.19
rpoC 763702 c.333C>G synonymous_variant 0.19
rpoC 763709 c.340C>T synonymous_variant 0.18
rpoC 763714 c.345G>C synonymous_variant 0.18
rpoC 763717 c.348T>C synonymous_variant 0.18
rpoC 763723 c.354G>C synonymous_variant 0.19
rpoC 763741 c.372C>T synonymous_variant 0.2
rpoC 763747 c.378G>A synonymous_variant 0.18
rpoC 763765 c.396T>G synonymous_variant 0.19
rpoC 763783 c.414G>C synonymous_variant 0.17
rpoC 763792 p.Glu141Asp missense_variant 0.16
rpoC 763807 c.438T>C synonymous_variant 0.16
rpoC 763813 c.444C>G synonymous_variant 0.18
rpoC 763831 c.462A>G synonymous_variant 0.16
rpoC 763837 c.468G>C synonymous_variant 0.16
rpoC 763840 c.471G>C synonymous_variant 0.15
rpoC 763900 c.531G>C synonymous_variant 0.13
rpoC 763921 c.552G>C synonymous_variant 0.14
rpoC 763924 c.555G>A synonymous_variant 0.14
rpoC 764344 c.975C>T synonymous_variant 0.13
rpoC 764353 c.984G>T synonymous_variant 0.12
rpoC 764365 c.996C>T synonymous_variant 0.14
rpoC 764380 c.1011G>C synonymous_variant 0.14
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.17
rpoC 764431 c.1062G>C synonymous_variant 0.15
rpoC 764434 c.1065A>G synonymous_variant 0.15
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.15
rpoC 764446 c.1077T>C synonymous_variant 0.17
rpoC 764449 c.1080G>C synonymous_variant 0.17
rpoC 764452 c.1083T>C synonymous_variant 0.18
rpoC 764458 c.1089G>C synonymous_variant 0.18
rpoC 764461 c.1092A>G synonymous_variant 0.18
rpoC 764485 c.1116G>C synonymous_variant 0.19
rpoC 764491 c.1122G>T synonymous_variant 0.19
rpoC 764497 c.1128A>G synonymous_variant 0.19
rpoC 764500 c.1131C>G synonymous_variant 0.17
rpoC 764521 c.1152T>C synonymous_variant 0.19
rpoC 764527 c.1158C>T synonymous_variant 0.19
rpoC 764536 c.1167G>T synonymous_variant 0.18
rpoC 764539 c.1170C>G synonymous_variant 0.18
rpoC 764548 c.1179G>T synonymous_variant 0.19
rpoC 764575 c.1206T>G synonymous_variant 0.19
rpoC 764605 c.1236G>C synonymous_variant 0.2
rpoC 764611 c.1242G>T synonymous_variant 0.21
rpoC 764623 c.1254C>G synonymous_variant 0.21
rpoC 764626 c.1257C>T synonymous_variant 0.21
rpoC 764632 c.1263T>C synonymous_variant 0.21
rpoC 764650 c.1281G>T synonymous_variant 0.19
rpoC 764701 c.1332C>G synonymous_variant 0.16
rpoC 764707 c.1338G>C synonymous_variant 0.14
rpoC 764713 c.1344G>T synonymous_variant 0.14
rpoC 764716 c.1347G>C synonymous_variant 0.14
rpoC 764746 c.1377G>T synonymous_variant 0.15
rpoC 764752 c.1383G>C synonymous_variant 0.16
rpoC 764758 c.1389C>G synonymous_variant 0.16
rpoC 764764 c.1395T>C synonymous_variant 0.16
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 765871 c.2502T>C synonymous_variant 0.13
rpoC 765875 p.Val836Ile missense_variant 0.13
rpoC 765886 c.2517C>G synonymous_variant 0.14
rpoC 765934 c.2565C>T synonymous_variant 0.13
rpoC 765937 c.2568T>C synonymous_variant 0.13
rpoC 765940 c.2571A>T synonymous_variant 0.13
rpoC 765946 c.2577C>T synonymous_variant 0.13
rpoC 765947 c.2578T>C synonymous_variant 0.14
rpoC 765952 c.2583G>C synonymous_variant 0.14
rpoC 765961 c.2592G>T synonymous_variant 0.13
rpoC 765964 p.Leu865Phe missense_variant 0.13
rpoC 765967 c.2598C>T synonymous_variant 0.13
rpoC 765979 c.2610C>G synonymous_variant 0.13
rpoC 765982 c.2613C>T synonymous_variant 0.13
rpoC 765994 c.2625A>T synonymous_variant 0.13
rpoC 766963 c.3594T>C synonymous_variant 0.12
rpoC 767002 c.3633G>C synonymous_variant 0.13
rpoC 767008 c.3639G>A synonymous_variant 0.13
rpoC 767020 c.3651C>G synonymous_variant 0.14
rpoC 767023 c.3654C>T synonymous_variant 0.15
rpoC 767059 c.3690T>C synonymous_variant 0.14
rpoC 767098 c.3729T>C synonymous_variant 0.13
rpoC 767180 p.Ala1271Gln missense_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781929 p.Gly124Ser missense_variant 0.13
fbiC 1304544 c.1614T>C synonymous_variant 0.13
fbiC 1304547 c.1617C>G synonymous_variant 0.13
fbiC 1304559 p.Glu543Asp missense_variant 0.14
fbiC 1304562 c.1632G>C synonymous_variant 0.14
fbiC 1304565 c.1635C>G synonymous_variant 0.14
fbiC 1304568 c.1638T>C synonymous_variant 0.14
fbiC 1304571 c.1641G>C synonymous_variant 0.13
fbiC 1304580 c.1650T>C synonymous_variant 0.13
fbiC 1304682 c.1752C>T synonymous_variant 0.12
fbiC 1305494 c.2565_*55delGGCCTAGCCCCGGCGACGATGCCGGGTCGCGGGATGCGGCCCGTTGAGGAGCGGGGCAATCT frameshift_variant&stop_lost&splice_region_variant 0.26
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.19
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.22
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.22
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.22
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.21
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.22
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.23
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.26
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.27
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.3
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.25
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.25
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.23
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.2
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 0.13
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.13
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.13
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.13
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.14
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.13
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.14
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.14
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.14
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 0.14
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.16
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.23
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.2
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.2
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.19
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.22
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.22
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.23
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.23
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.23
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.23
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.28
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.28
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.26
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.26
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.17
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.14
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.15
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.17
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.15
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.17
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.16
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.16
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.16
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.16
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.16
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.16
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.16
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.16
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.14
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.14
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.14
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.14
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.14
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.14
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.14
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.16
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.15
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.16
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.16
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.16
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.17
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.18
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.19
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.18
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.18
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.18
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.18
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.18
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.19
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.19
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.19
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.19
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.19
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.19
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.19
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.19
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.19
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.19
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.21
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.17
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.14
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.14
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.13
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.13
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.16
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.26
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.25
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.24
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.21
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.21
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.22
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.24
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.25
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.23
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.22
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.23
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.23
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.26
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.28
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.28
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.33
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.33
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.32
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.3
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.28
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.29
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.29
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.29
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.29
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.25
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.26
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.2
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.2
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.2
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.2
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.2
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.18
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.14
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.14
inhA 1674477 c.276G>T synonymous_variant 0.13
inhA 1674486 c.285T>C synonymous_variant 0.14
inhA 1674503 p.Thr101Ser missense_variant 0.14
rpsA 1834162 c.621A>G synonymous_variant 0.15
rpsA 1834169 p.Thr210Ala missense_variant 0.14
rpsA 1834177 c.636A>C synonymous_variant 0.14
rpsA 1834189 c.648G>C synonymous_variant 0.15
rpsA 1834213 c.672G>C synonymous_variant 0.15
rpsA 1834234 c.693G>C synonymous_variant 0.16
rpsA 1834240 c.699T>C synonymous_variant 0.16
rpsA 1834243 c.702G>C synonymous_variant 0.16
rpsA 1834249 c.708T>C synonymous_variant 0.18
rpsA 1834261 c.720A>G synonymous_variant 0.19
rpsA 1834264 c.723G>C synonymous_variant 0.18
rpsA 1834279 c.738C>T synonymous_variant 0.21
rpsA 1834297 c.756C>T synonymous_variant 0.21
rpsA 1834303 c.762T>G synonymous_variant 0.21
rpsA 1834306 c.765T>C synonymous_variant 0.21
rpsA 1834330 c.789C>G synonymous_variant 0.2
rpsA 1834345 c.804C>T synonymous_variant 0.16
rpsA 1834348 c.807T>C synonymous_variant 0.17
rpsA 1834361 c.820T>C synonymous_variant 0.19
rpsA 1834366 c.825A>G synonymous_variant 0.19
rpsA 1834387 c.846C>T synonymous_variant 0.19
rpsA 1834396 c.855G>T synonymous_variant 0.2
rpsA 1834411 c.870T>C synonymous_variant 0.21
rpsA 1834423 c.882G>T synonymous_variant 0.21
rpsA 1834432 c.891G>T synonymous_variant 0.23
rpsA 1834451 c.910T>C synonymous_variant 0.23
rpsA 1834456 c.915T>G synonymous_variant 0.23
rpsA 1834468 c.927A>G synonymous_variant 0.22
rpsA 1834513 c.972C>G synonymous_variant 0.2
rpsA 1834520 p.Ala327Ser missense_variant 0.2
rpsA 1834528 c.987T>C synonymous_variant 0.2
rpsA 1834540 c.999G>C synonymous_variant 0.18
rpsA 1834543 c.1002C>G synonymous_variant 0.18
rpsA 1834546 c.1005T>C synonymous_variant 0.17
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.18
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714432 p.Val301Ile missense_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 0.99
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
rpoA 3877803 c.705G>C synonymous_variant 0.15
rpoA 3877818 c.690A>G synonymous_variant 0.15
rpoA 3877839 c.669G>C synonymous_variant 0.15
rpoA 3877848 c.660C>T synonymous_variant 0.15
rpoA 3877857 c.651G>A synonymous_variant 0.15
rpoA 3877866 c.642G>C synonymous_variant 0.16
rpoA 3877875 c.633T>C synonymous_variant 0.16
rpoA 3877887 c.621G>C synonymous_variant 0.17
rpoA 3877893 c.615C>T synonymous_variant 0.17
rpoA 3877905 c.603A>G synonymous_variant 0.18
rpoA 3877908 c.600T>C synonymous_variant 0.17
rpoA 3877920 c.588G>C synonymous_variant 0.18
rpoA 3877926 c.582G>C synonymous_variant 0.19
rpoA 3877929 c.579C>T synonymous_variant 0.19
rpoA 3877962 c.546G>T synonymous_variant 0.22
rpoA 3877971 p.Asp179Glu missense_variant 0.19
rpoA 3877974 c.534G>T synonymous_variant 0.19
rpoA 3877989 c.519A>G synonymous_variant 0.22
rpoA 3877992 c.516C>G synonymous_variant 0.21
rpoA 3877998 c.510G>C synonymous_variant 0.21
rpoA 3878001 c.505_507delTCAinsAGC synonymous_variant 0.2
rpoA 3878019 c.489A>G synonymous_variant 0.21
rpoA 3878022 c.486T>C synonymous_variant 0.21
rpoA 3878025 c.483C>T synonymous_variant 0.21
rpoA 3878028 c.480G>C synonymous_variant 0.22
rpoA 3878031 c.477T>C synonymous_variant 0.21
rpoA 3878034 c.474A>G synonymous_variant 0.22
rpoA 3878046 c.462T>C synonymous_variant 0.23
rpoA 3878050 p.Arg153Lys missense_variant 0.22
rpoA 3878055 c.453A>G synonymous_variant 0.21
rpoA 3878061 c.447G>C synonymous_variant 0.22
rpoA 3878070 c.438T>C synonymous_variant 0.21
rpoA 3878079 c.429C>T synonymous_variant 0.22
rpoA 3878082 c.426T>G synonymous_variant 0.22
rpoA 3878103 c.405A>G synonymous_variant 0.19
rpoA 3878106 c.402G>C synonymous_variant 0.19
rpoA 3878118 c.390T>C synonymous_variant 0.15
rpoA 3878124 c.384G>C synonymous_variant 0.14
rpoA 3878127 c.381G>C synonymous_variant 0.14
rpoA 3878143 p.Gly122Asp missense_variant 0.16
rpoA 3878145 c.363C>G synonymous_variant 0.17
rpoA 3878154 c.354G>C synonymous_variant 0.18
rpoA 3878160 c.348C>G synonymous_variant 0.2
rpoA 3878163 c.345C>T synonymous_variant 0.19
rpoA 3878184 c.324C>T synonymous_variant 0.18
rpoA 3878193 c.315T>C synonymous_variant 0.17
rpoA 3878196 p.Glu104Ala missense_variant 0.17
rpoA 3878205 c.303T>C synonymous_variant 0.17
rpoA 3878217 c.291A>G synonymous_variant 0.15
rpoA 3878244 c.264G>A synonymous_variant 0.14
rpoA 3878247 c.261G>C synonymous_variant 0.14
rpoA 3878639 c.-132C>G upstream_gene_variant 0.17
rpoA 3878641 c.-135_-134insG upstream_gene_variant 0.17
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4038941 c.1764G>C synonymous_variant 0.13
clpC1 4038953 c.1752A>G synonymous_variant 0.15
clpC1 4038956 c.1749T>C synonymous_variant 0.14
clpC1 4038965 c.1740T>C synonymous_variant 0.15
clpC1 4038971 c.1734T>C synonymous_variant 0.14
clpC1 4038974 c.1731T>C synonymous_variant 0.15
clpC1 4038989 c.1716T>C synonymous_variant 0.15
clpC1 4038997 c.1708T>C synonymous_variant 0.16
clpC1 4039022 c.1683A>G synonymous_variant 0.17
clpC1 4039067 c.1638G>T synonymous_variant 0.16
clpC1 4039079 c.1626C>G synonymous_variant 0.16
clpC1 4039085 c.1620A>G synonymous_variant 0.15
clpC1 4039091 c.1614G>C synonymous_variant 0.15
clpC1 4039097 c.1608G>T synonymous_variant 0.14
clpC1 4039100 c.1605C>T synonymous_variant 0.15
clpC1 4039103 c.1602T>C synonymous_variant 0.15
clpC1 4039106 c.1599G>C synonymous_variant 0.15
clpC1 4039136 c.1569C>T synonymous_variant 0.14
clpC1 4039142 c.1563A>G synonymous_variant 0.16
clpC1 4039145 c.1560G>C synonymous_variant 0.16
clpC1 4039169 c.1536A>G synonymous_variant 0.16
clpC1 4039178 c.1527G>C synonymous_variant 0.14
clpC1 4039183 c.1522T>C synonymous_variant 0.14
clpC1 4039187 c.1518G>T synonymous_variant 0.14
clpC1 4039190 c.1515C>G synonymous_variant 0.13
clpC1 4039199 c.1506C>G synonymous_variant 0.15
clpC1 4039241 c.1464G>C synonymous_variant 0.15
clpC1 4039274 c.1431G>A synonymous_variant 0.17
clpC1 4039277 c.1428C>G synonymous_variant 0.15
clpC1 4039280 c.1425G>C synonymous_variant 0.15
clpC1 4039286 c.1419T>C synonymous_variant 0.15
clpC1 4039292 c.1413C>T synonymous_variant 0.15
clpC1 4039295 c.1410A>G synonymous_variant 0.14
clpC1 4039310 c.1395A>G synonymous_variant 0.13
clpC1 4039313 c.1392C>G synonymous_variant 0.14
clpC1 4039321 p.Ala462Ser missense_variant 0.12
clpC1 4039338 p.Thr456Gln missense_variant 0.13
clpC1 4039346 c.1359G>C synonymous_variant 0.13
clpC1 4039352 c.1353C>G synonymous_variant 0.13
clpC1 4039361 c.1344C>A synonymous_variant 0.13
clpC1 4039517 c.1188C>G synonymous_variant 0.13
clpC1 4039553 c.1152C>G synonymous_variant 0.13
clpC1 4039559 c.1146C>G synonymous_variant 0.14
clpC1 4039570 p.Met379Leu missense_variant 0.14
clpC1 4039574 p.Ala377Gly missense_variant 0.14
clpC1 4039577 c.1128T>C synonymous_variant 0.14
clpC1 4039589 c.1116G>C synonymous_variant 0.14
clpC1 4039592 c.1113G>C synonymous_variant 0.14
clpC1 4039598 c.1107C>T synonymous_variant 0.17
clpC1 4039610 c.1095G>C synonymous_variant 0.17
clpC1 4039622 c.1083C>T synonymous_variant 0.17
clpC1 4039649 c.1056G>C synonymous_variant 0.15
clpC1 4039652 c.1053G>C synonymous_variant 0.15
clpC1 4039664 c.1041G>C synonymous_variant 0.16
clpC1 4039670 c.1035G>C synonymous_variant 0.17
clpC1 4039682 c.1023C>G synonymous_variant 0.18
clpC1 4039694 c.1011G>C synonymous_variant 0.21
clpC1 4039724 c.981A>G synonymous_variant 0.19
clpC1 4039733 c.972G>C synonymous_variant 0.22
clpC1 4039742 c.963C>T synonymous_variant 0.21
clpC1 4039748 c.957G>C synonymous_variant 0.19
clpC1 4039751 c.954A>G synonymous_variant 0.19
clpC1 4039757 c.948A>G synonymous_variant 0.19
clpC1 4039760 c.945T>C synonymous_variant 0.18
clpC1 4039769 c.936C>G synonymous_variant 0.18
clpC1 4039778 c.927A>G synonymous_variant 0.17
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.16
clpC1 4039793 c.912C>G synonymous_variant 0.17
clpC1 4039802 c.903G>C synonymous_variant 0.17
clpC1 4039817 c.888A>T synonymous_variant 0.16
clpC1 4039820 c.885T>G synonymous_variant 0.17
clpC1 4039829 p.Leu292Phe missense_variant 0.14
clpC1 4039832 c.873C>G synonymous_variant 0.12
clpC1 4039844 c.861C>T synonymous_variant 0.13
clpC1 4039850 c.855T>C synonymous_variant 0.13
clpC1 4039865 c.840T>C synonymous_variant 0.14
clpC1 4039898 c.807C>G synonymous_variant 0.13
clpC1 4039904 c.801A>G synonymous_variant 0.13
clpC1 4039913 c.792C>T synonymous_variant 0.14
clpC1 4040126 c.579C>T synonymous_variant 0.16
clpC1 4040141 c.564C>T synonymous_variant 0.13
clpC1 4040144 c.561G>C synonymous_variant 0.13
clpC1 4040147 c.558A>G synonymous_variant 0.13
clpC1 4040159 c.546G>C synonymous_variant 0.14
clpC1 4040162 c.543G>C synonymous_variant 0.14
clpC1 4040165 c.540G>C synonymous_variant 0.14
clpC1 4040168 c.537G>C synonymous_variant 0.14
clpC1 4040171 c.534C>G synonymous_variant 0.14
clpC1 4040177 c.528C>T synonymous_variant 0.16
clpC1 4040195 c.510G>C synonymous_variant 0.16
clpC1 4040200 c.505T>C synonymous_variant 0.17
clpC1 4040201 c.504C>G synonymous_variant 0.16
clpC1 4040207 c.498T>G synonymous_variant 0.15
clpC1 4040213 p.Ser164Asn missense_variant 0.16
clpC1 4040219 c.486C>G synonymous_variant 0.16
clpC1 4040225 c.480A>C synonymous_variant 0.16
clpC1 4040228 c.477G>A synonymous_variant 0.16
clpC1 4040231 c.474C>T synonymous_variant 0.16
clpC1 4040237 c.468C>T synonymous_variant 0.18
clpC1 4040249 c.456A>G synonymous_variant 0.2
clpC1 4040258 c.447G>A synonymous_variant 0.2
clpC1 4040267 c.438A>G synonymous_variant 0.2
clpC1 4040273 c.432T>C synonymous_variant 0.18
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.17
clpC1 4040279 c.426C>G synonymous_variant 0.17
clpC1 4040300 c.405C>T synonymous_variant 0.17
clpC1 4040306 c.399G>C synonymous_variant 0.15
embC 4239763 c.-100C>T upstream_gene_variant 0.99
embC 4240382 p.Gly174Arg missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0
fbiC 1305494 c.2565_*56delCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN frameshift_variant&stop_lost&splice_region_variant 1.0