TB-Profiler result

Run: ERR176518
Summary

Run ID: ERR176518

Sample name:

Date: 31-03-2023 15:03:50

Number of reads: 2051335

Percentage reads mapped: 76.04

Strain: lineage4.3.4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.2 Euro-American (LAM) LAM1;LAM4;LAM11 RD174 0.96
lineage4.3.4.2.1 Euro-American (LAM) LAM11 RD174 0.97
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6140 p.Val301Leu missense_variant 0.95
gyrA 6904 c.-398C>G upstream_gene_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7394 c.93T>C synonymous_variant 0.14
gyrA 7406 c.105G>C synonymous_variant 0.14
gyrA 7415 c.114C>A synonymous_variant 0.15
gyrA 7418 c.117C>T synonymous_variant 0.14
gyrA 7427 c.126G>C synonymous_variant 0.14
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7607 c.306C>G synonymous_variant 0.18
gyrA 7622 c.321C>T synonymous_variant 0.18
gyrA 7631 c.330G>C synonymous_variant 0.16
gyrA 7637 c.336C>G synonymous_variant 0.16
gyrA 7652 c.351C>T synonymous_variant 0.14
gyrA 7658 c.357A>G synonymous_variant 0.14
gyrA 7763 c.462T>G synonymous_variant 0.15
gyrA 7781 c.480G>T synonymous_variant 0.13
gyrA 7784 c.483A>G synonymous_variant 0.15
gyrA 7793 c.492G>C synonymous_variant 0.14
gyrA 7799 c.498A>G synonymous_variant 0.14
gyrA 8177 c.876A>C synonymous_variant 0.13
gyrA 8189 c.888G>C synonymous_variant 0.13
gyrA 8198 c.897T>C synonymous_variant 0.13
gyrA 8207 c.906T>C synonymous_variant 0.13
gyrA 8219 c.918T>C synonymous_variant 0.12
gyrA 8225 c.924T>C synonymous_variant 0.13
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.15
gyrA 8247 p.Ile316Val missense_variant 0.23
gyrA 8253 p.Ile318Leu missense_variant 0.22
gyrA 8261 c.960C>A synonymous_variant 0.2
gyrA 8264 c.963T>C synonymous_variant 0.19
gyrA 8267 c.966G>C synonymous_variant 0.21
gyrA 8283 p.Ile328Leu missense_variant 0.2
gyrA 8288 c.987T>C synonymous_variant 0.23
gyrA 8294 c.993T>C synonymous_variant 0.24
gyrA 8324 c.1023T>C synonymous_variant 0.26
gyrA 8330 c.1029C>G synonymous_variant 0.24
gyrA 8339 c.1038A>C synonymous_variant 0.15
gyrA 8340 p.Ala347Ser missense_variant 0.14
gyrA 8366 c.1065G>C synonymous_variant 0.12
gyrA 8382 p.Leu361Met missense_variant 0.12
gyrA 8852 c.1551T>G synonymous_variant 0.15
gyrA 8858 c.1557T>G synonymous_variant 0.16
gyrA 8867 c.1566A>G synonymous_variant 0.15
gyrA 8873 c.1572A>G synonymous_variant 0.16
gyrA 8897 c.1596T>C synonymous_variant 0.17
gyrA 8900 c.1599G>C synonymous_variant 0.17
gyrA 8903 c.1602T>C synonymous_variant 0.17
gyrA 9267 p.Asn656Gly missense_variant 0.16
gyrA 9296 c.1995T>C synonymous_variant 0.13
gyrA 9299 c.1998G>C synonymous_variant 0.13
gyrA 9300 p.Ala667Ser missense_variant 0.14
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9323 c.2022C>G synonymous_variant 0.18
gyrA 9329 c.2028C>G synonymous_variant 0.14
gyrA 9335 c.2034G>C synonymous_variant 0.13
gyrA 9341 c.2040C>G synonymous_variant 0.12
ccsA 620649 c.759A>G synonymous_variant 0.14
ccsA 620661 c.771C>G synonymous_variant 0.2
ccsA 620691 c.801G>C synonymous_variant 0.19
ccsA 620694 c.804C>G synonymous_variant 0.16
ccsA 620698 p.Val270Ile missense_variant 0.18
ccsA 620703 c.813G>C synonymous_variant 0.17
ccsA 620721 c.831G>C synonymous_variant 0.2
ccsA 620724 c.834C>T synonymous_variant 0.2
ccsA 620739 c.849A>G synonymous_variant 0.21
ccsA 620745 c.855G>C synonymous_variant 0.19
ccsA 620748 c.858T>C synonymous_variant 0.21
ccsA 620778 c.888T>C synonymous_variant 0.16
ccsA 620783 p.Ala298Val missense_variant 0.14
ccsA 620787 c.897C>A synonymous_variant 0.14
ccsA 620793 c.903G>C synonymous_variant 0.14
rpoB 760139 c.333A>G synonymous_variant 0.14
rpoB 760181 c.375T>C synonymous_variant 0.17
rpoB 760184 c.378A>G synonymous_variant 0.17
rpoB 760196 c.390C>G synonymous_variant 0.21
rpoB 760223 c.417T>C synonymous_variant 0.31
rpoB 760235 c.429T>C synonymous_variant 0.31
rpoB 760271 c.465C>G synonymous_variant 0.29
rpoB 760283 c.477G>C synonymous_variant 0.23
rpoB 760298 c.492G>C synonymous_variant 0.18
rpoB 760307 c.501T>C synonymous_variant 0.14
rpoB 760313 c.507G>C synonymous_variant 0.15
rpoB 760325 c.519G>C synonymous_variant 0.17
rpoB 760328 c.522G>C synonymous_variant 0.18
rpoB 760340 c.534G>T synonymous_variant 0.18
rpoB 760361 c.555T>C synonymous_variant 0.21
rpoB 760376 p.Asp190Glu missense_variant 0.22
rpoB 760400 c.594G>C synonymous_variant 0.23
rpoB 760406 c.600G>C synonymous_variant 0.22
rpoB 760407 p.Ser201Gly missense_variant 0.2
rpoB 760415 c.609C>T synonymous_variant 0.2
rpoB 760424 c.618C>G synonymous_variant 0.18
rpoB 760430 c.624T>C synonymous_variant 0.18
rpoB 760460 c.654G>C synonymous_variant 0.15
rpoB 760511 c.705G>C synonymous_variant 0.15
rpoB 760522 p.Ser239Asn missense_variant 0.15
rpoB 760532 c.726T>C synonymous_variant 0.14
rpoB 760533 p.Val243Thr missense_variant 0.14
rpoB 760541 c.735G>C synonymous_variant 0.15
rpoB 760547 c.741G>C synonymous_variant 0.15
rpoB 760566 p.Ser254Ala missense_variant 0.15
rpoB 760567 c.762delG frameshift_variant 0.15
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 0.13
rpoB 760625 c.819C>G synonymous_variant 0.15
rpoB 760646 c.840C>G synonymous_variant 0.18
rpoB 760655 c.849A>G synonymous_variant 0.21
rpoB 760661 c.855A>C synonymous_variant 0.22
rpoB 760670 c.864G>C synonymous_variant 0.22
rpoB 760674 c.868T>C synonymous_variant 0.21
rpoB 760679 c.873A>G synonymous_variant 0.22
rpoB 760683 c.877T>C synonymous_variant 0.22
rpoB 760703 c.897C>T synonymous_variant 0.14
rpoB 760910 c.1104C>T synonymous_variant 0.14
rpoB 760916 c.1110C>T synonymous_variant 0.14
rpoB 760919 c.1113C>T synonymous_variant 0.13
rpoB 760928 c.1122G>C synonymous_variant 0.12
rpoB 760931 c.1125C>G synonymous_variant 0.15
rpoB 760946 c.1140A>G synonymous_variant 0.17
rpoB 760965 p.Met387Leu missense_variant 0.16
rpoB 761133 c.1327T>C synonymous_variant 0.13
rpoB 761318 c.1512G>C synonymous_variant 0.14
rpoB 761570 c.1764T>C synonymous_variant 0.16
rpoB 761573 c.1767C>G synonymous_variant 0.15
rpoB 761579 c.1773G>C synonymous_variant 0.15
rpoB 761612 c.1806G>T synonymous_variant 0.17
rpoB 761615 c.1809A>C synonymous_variant 0.19
rpoB 761636 c.1830G>T synonymous_variant 0.14
rpoB 761645 c.1839C>G synonymous_variant 0.14
rpoB 761648 c.1842T>C synonymous_variant 0.12
rpoB 761892 p.Ile696Val missense_variant 0.12
rpoB 761972 c.2166C>T synonymous_variant 0.14
rpoB 761999 c.2193G>C synonymous_variant 0.21
rpoB 762014 c.2208C>G synonymous_variant 0.24
rpoB 762017 c.2211A>G synonymous_variant 0.24
rpoB 762053 c.2247T>C synonymous_variant 0.3
rpoB 762065 c.2259T>C synonymous_variant 0.26
rpoB 762083 c.2277T>C synonymous_variant 0.18
rpoB 762086 c.2280G>C synonymous_variant 0.17
rpoB 762101 c.2295C>G synonymous_variant 0.16
rpoB 762114 p.Ile770Val missense_variant 0.19
rpoB 762122 c.2316C>T synonymous_variant 0.13
rpoB 762131 c.2325C>G synonymous_variant 0.13
rpoB 762176 c.2370T>C synonymous_variant 0.13
rpoB 762179 c.2373C>A synonymous_variant 0.13
rpoB 762185 c.2379G>C synonymous_variant 0.16
rpoB 762209 c.2403C>T synonymous_variant 0.21
rpoB 762233 c.2427G>C synonymous_variant 0.17
rpoB 762251 c.2445G>C synonymous_variant 0.19
rpoB 762257 c.2451C>G synonymous_variant 0.19
rpoB 762275 c.2469C>G synonymous_variant 0.14
rpoB 762284 c.2478G>T synonymous_variant 0.16
rpoB 762293 c.2487T>G synonymous_variant 0.14
rpoB 762299 c.2493G>C synonymous_variant 0.14
rpoC 762410 c.-960T>C upstream_gene_variant 0.13
rpoC 762416 c.-954A>G upstream_gene_variant 0.13
rpoC 762443 c.-927G>C upstream_gene_variant 0.14
rpoC 762449 c.-921C>A upstream_gene_variant 0.13
rpoC 762452 c.-918G>C upstream_gene_variant 0.13
rpoC 762917 c.-453C>G upstream_gene_variant 0.21
rpoC 762923 c.-447C>G upstream_gene_variant 0.2
rpoC 762929 c.-441G>T upstream_gene_variant 0.21
rpoC 762959 c.-411G>C upstream_gene_variant 0.18
rpoC 762962 c.-408C>T upstream_gene_variant 0.18
rpoC 762983 c.-387C>T upstream_gene_variant 0.23
rpoC 762995 c.-375G>C upstream_gene_variant 0.18
rpoC 763028 c.-342T>C upstream_gene_variant 0.18
rpoC 763031 c.-339T>C upstream_gene_variant 0.17
rpoC 763040 c.-330C>G upstream_gene_variant 0.17
rpoC 763058 c.-312C>G upstream_gene_variant 0.2
rpoC 763070 c.-300T>C upstream_gene_variant 0.23
rpoC 763100 c.-270G>A upstream_gene_variant 0.21
rpoC 763103 c.-267G>C upstream_gene_variant 0.21
rpoC 763115 c.-255T>C upstream_gene_variant 0.16
rpoC 763127 c.-243G>C upstream_gene_variant 0.16
rpoC 763468 c.99G>C synonymous_variant 0.12
rpoC 763495 c.126G>A synonymous_variant 0.11
rpoC 763528 c.159G>A synonymous_variant 0.18
rpoC 763546 c.177A>G synonymous_variant 0.22
rpoC 763570 c.201G>C synonymous_variant 0.22
rpoC 763594 c.225C>T synonymous_variant 0.21
rpoC 763633 c.264T>C synonymous_variant 0.2
rpoC 763642 c.273G>C synonymous_variant 0.17
rpoC 763660 c.291T>G synonymous_variant 0.17
rpoC 763666 c.297G>A synonymous_variant 0.17
rpoC 763675 c.306C>G synonymous_variant 0.18
rpoC 763699 c.330G>C synonymous_variant 0.2
rpoC 763702 c.333C>G synonymous_variant 0.19
rpoC 763714 c.345G>C synonymous_variant 0.18
rpoC 763717 c.348T>C synonymous_variant 0.18
rpoC 763741 c.372C>T synonymous_variant 0.18
rpoC 763744 c.375G>C synonymous_variant 0.18
rpoC 763765 c.396T>G synonymous_variant 0.13
rpoC 764059 c.690G>T synonymous_variant 0.18
rpoC 764083 c.714A>G synonymous_variant 0.16
rpoC 764084 p.Asn239Val missense_variant 0.16
rpoC 764098 c.729A>G synonymous_variant 0.17
rpoC 764131 c.762T>C synonymous_variant 0.18
rpoC 764153 p.Gln262Lys missense_variant 0.11
rpoC 764320 c.951C>T synonymous_variant 0.15
rpoC 764353 c.984G>C synonymous_variant 0.21
rpoC 764365 c.996C>T synonymous_variant 0.16
rpoC 764371 c.1002G>C synonymous_variant 0.14
rpoC 764380 c.1011G>C synonymous_variant 0.15
rpoC 764387 c.1018T>C synonymous_variant 0.15
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.14
rpoC 764485 c.1116G>C synonymous_variant 0.13
rpoC 764491 c.1122G>C synonymous_variant 0.14
rpoC 764545 c.1176C>G synonymous_variant 0.13
rpoC 764548 c.1179G>A synonymous_variant 0.15
rpoC 764551 c.1182G>C synonymous_variant 0.16
rpoC 764566 c.1197C>G synonymous_variant 0.16
rpoC 764575 c.1206T>G synonymous_variant 0.15
rpoC 764611 c.1242G>T synonymous_variant 0.14
rpoC 764650 c.1281G>T synonymous_variant 0.18
rpoC 764716 c.1347G>C synonymous_variant 0.2
rpoC 764746 c.1377G>T synonymous_variant 0.24
rpoC 764752 c.1383G>C synonymous_variant 0.28
rpoC 764758 c.1389C>G synonymous_variant 0.29
rpoC 764764 c.1395T>C synonymous_variant 0.3
rpoC 764803 c.1434C>T synonymous_variant 0.36
rpoC 764809 c.1440C>T synonymous_variant 0.38
rpoC 764815 c.1446A>G synonymous_variant 0.36
rpoC 764827 c.1458G>C synonymous_variant 0.3
rpoC 764858 c.1489T>C synonymous_variant 0.26
rpoC 764878 c.1509C>G synonymous_variant 0.23
rpoC 764887 c.1518G>C synonymous_variant 0.2
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 0.2
rpoC 764908 c.1539G>A synonymous_variant 0.12
rpoC 764926 c.1557C>T synonymous_variant 0.13
rpoC 764995 c.1626C>G synonymous_variant 0.94
rpoC 765425 p.Lys686Glu missense_variant 0.13
rpoC 765811 c.2442T>C synonymous_variant 0.15
rpoC 765814 c.2445A>C synonymous_variant 0.15
rpoC 765820 c.2451G>C synonymous_variant 0.15
rpoC 765823 c.2454C>G synonymous_variant 0.15
rpoC 765826 c.2457T>C synonymous_variant 0.15
rpoC 765835 c.2466C>T synonymous_variant 0.16
rpoC 765871 c.2502T>G synonymous_variant 0.17
rpoC 765875 p.Val836Ile missense_variant 0.18
rpoC 765886 c.2517C>G synonymous_variant 0.15
rpoC 765892 c.2523T>C synonymous_variant 0.14
rpoC 765904 c.2535C>G synonymous_variant 0.17
rpoC 765937 c.2568T>C synonymous_variant 0.22
rpoC 765940 c.2571A>T synonymous_variant 0.22
rpoC 765946 c.2577C>T synonymous_variant 0.21
rpoC 765947 c.2578T>C synonymous_variant 0.21
rpoC 765958 c.2589C>G synonymous_variant 0.21
rpoC 765962 c.2593_2595delTTGinsCTT synonymous_variant 0.19
rpoC 765967 c.2598C>T synonymous_variant 0.19
rpoC 765979 c.2610C>G synonymous_variant 0.2
rpoC 765982 c.2613C>T synonymous_variant 0.19
rpoC 765994 c.2625A>T synonymous_variant 0.18
rpoC 766518 p.Thr1050Ser missense_variant 0.19
rpoC 766525 c.3156G>C synonymous_variant 0.18
rpoC 766528 c.3159T>G synonymous_variant 0.16
rpoC 766530 p.Arg1054Gln missense_variant 0.16
rpoC 766540 p.Asp1057Glu missense_variant 0.22
rpoC 766543 c.3174C>T synonymous_variant 0.23
rpoC 766546 p.Glu1059Asp missense_variant 0.22
rpoC 766549 c.3180G>C synonymous_variant 0.22
rpoC 766570 c.3201T>C synonymous_variant 0.17
rpoC 766573 c.3204T>C synonymous_variant 0.15
rpoC 766582 c.3213C>T synonymous_variant 0.16
rpoC 766585 c.3216T>C synonymous_variant 0.16
rpoC 766597 c.3228C>G synonymous_variant 0.15
rpoC 766798 c.3429C>G synonymous_variant 0.14
rpoC 766801 c.3432C>G synonymous_variant 0.14
rpoC 766804 c.3435A>G synonymous_variant 0.12
rpoC 766807 c.3438T>C synonymous_variant 0.13
rpoC 766837 c.3468G>C synonymous_variant 0.12
rpoC 767206 c.3837C>G synonymous_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775937 c.2544G>C synonymous_variant 0.17
mmpL5 775946 c.2535C>G synonymous_variant 0.23
mmpL5 775961 c.2520C>G synonymous_variant 0.24
mmpL5 775966 p.Ala839Ser missense_variant 0.23
mmpL5 775975 c.2506T>C synonymous_variant 0.21
mmpL5 775981 p.Leu834Met missense_variant 0.24
mmpL5 775991 c.2490G>A synonymous_variant 0.19
mmpL5 775997 c.2484T>C synonymous_variant 0.19
mmpL5 776000 c.2481G>C synonymous_variant 0.15
mmpL5 776003 p.Ile826Leu missense_variant 0.15
mmpL5 776009 c.2472A>G synonymous_variant 0.19
mmpL5 776030 c.2451G>C synonymous_variant 0.2
mmpL5 776042 c.2439C>G synonymous_variant 0.16
mmpL5 777128 c.1353A>G synonymous_variant 0.12
mmpL5 777133 p.Val450Ile missense_variant 0.14
mmpL5 777142 p.Val447Leu missense_variant 0.16
mmpL5 777170 c.1311T>C synonymous_variant 0.16
mmpL5 777173 c.1308C>G synonymous_variant 0.16
mmpL5 777176 p.Glu435Asp missense_variant 0.16
mmpL5 777179 c.1302G>C synonymous_variant 0.17
mmpL5 777182 c.1299C>G synonymous_variant 0.18
mmpL5 777188 c.1293T>C synonymous_variant 0.21
mmpL5 777194 c.1287A>G synonymous_variant 0.2
mmpL5 777209 c.1272C>T synonymous_variant 0.18
mmpL5 777215 c.1266C>T synonymous_variant 0.17
mmpL5 777225 p.Asn419Ser missense_variant 0.17
mmpL5 777245 c.1236G>C synonymous_variant 0.16
mmpL5 777251 c.1230C>G synonymous_variant 0.14
mmpL5 777254 c.1227G>C synonymous_variant 0.14
mmpL5 777278 c.1203G>C synonymous_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781709 c.150G>C synonymous_variant 0.12
rpsL 781718 c.159C>T synonymous_variant 0.12
rpsL 781728 c.169T>C synonymous_variant 0.15
rpsL 781733 c.174G>C synonymous_variant 0.13
rpsL 781736 c.177T>C synonymous_variant 0.12
rpsL 781751 c.192G>C synonymous_variant 0.15
rpsL 781754 c.195G>C synonymous_variant 0.15
rpsL 781760 c.201T>C synonymous_variant 0.15
rpsL 781766 c.207C>T synonymous_variant 0.15
rpsL 781814 c.255C>T synonymous_variant 0.22
rpsL 781817 c.258G>T synonymous_variant 0.21
rpsL 781832 c.273T>C synonymous_variant 0.2
rpsL 781835 c.276T>C synonymous_variant 0.21
rpsL 781838 c.279G>C synonymous_variant 0.23
rpsL 781859 c.300T>C synonymous_variant 0.24
rpsL 781868 c.309T>C synonymous_variant 0.24
rpsL 781871 c.312G>C synonymous_variant 0.25
rpsL 781877 c.318T>C synonymous_variant 0.24
rpsL 781889 c.330C>T synonymous_variant 0.25
rpsL 781892 c.333A>G synonymous_variant 0.24
rpsL 781898 c.339A>C synonymous_variant 0.19
rpsL 781907 c.348T>C synonymous_variant 0.2
rpsL 781916 c.357T>G synonymous_variant 0.19
rplC 800645 c.-164C>G upstream_gene_variant 0.13
rplC 800648 c.-161A>C upstream_gene_variant 0.13
rplC 800654 c.-155T>C upstream_gene_variant 0.13
rplC 800693 c.-116A>C upstream_gene_variant 0.14
rplC 800720 c.-89T>C upstream_gene_variant 0.14
fbiC 1303525 p.Ser199Ala missense_variant 0.16
fbiC 1303531 p.Met201Leu missense_variant 0.15
fbiC 1303542 c.612C>G synonymous_variant 0.16
fbiC 1303545 c.615A>G synonymous_variant 0.16
fbiC 1303554 c.624G>A synonymous_variant 0.2
fbiC 1303575 c.645G>C synonymous_variant 0.23
fbiC 1303581 c.651G>C synonymous_variant 0.2
fbiC 1303584 c.654C>G synonymous_variant 0.2
fbiC 1303590 c.660A>T synonymous_variant 0.18
fbiC 1303598 p.Phe223Tyr missense_variant 0.16
fbiC 1303602 c.672A>G synonymous_variant 0.15
fbiC 1303605 c.675C>G synonymous_variant 0.15
fbiC 1304613 c.1683T>G synonymous_variant 0.12
fbiC 1304637 c.1707G>A synonymous_variant 0.12
fbiC 1304658 c.1728C>G synonymous_variant 0.14
fbiC 1304664 c.1734G>C synonymous_variant 0.14
fbiC 1304682 c.1752C>G synonymous_variant 0.12
fbiC 1304691 c.1761G>C synonymous_variant 0.12
fbiC 1305318 c.2388C>G synonymous_variant 0.13
fbiC 1305330 c.2400C>G synonymous_variant 0.15
fbiC 1305331 p.Glu801Gln missense_variant 0.15
fbiC 1305336 c.2406T>C synonymous_variant 0.15
fbiC 1305339 c.2409C>T synonymous_variant 0.15
fbiC 1305351 c.2421G>C synonymous_variant 0.15
fbiC 1305381 c.2451G>C synonymous_variant 0.17
fbiC 1305393 c.2463T>A synonymous_variant 0.13
fbiC 1305400 p.His824Asn missense_variant 0.12
fbiC 1305405 c.2475A>G synonymous_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.16
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.15
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.16
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.16
rrs 1472324 n.479G>T non_coding_transcript_exon_variant 0.12
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.12
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.3
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.32
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.36
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.26
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.27
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.25
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.28
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.28
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.27
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.38
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.34
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.33
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.34
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.34
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.32
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.32
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.14
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.14
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.16
rrl 1473728 n.71A>T non_coding_transcript_exon_variant 0.18
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.17
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.17
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.17
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.18
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.18
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.17
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.17
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.18
rrl 1473831 n.174G>A non_coding_transcript_exon_variant 0.2
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.2
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.2
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.12
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.15
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.14
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.14
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.14
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.14
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.18
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.18
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.13
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.13
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.16
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.16
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.16
rrl 1474498 n.841G>A non_coding_transcript_exon_variant 0.15
rrl 1474505 n.848C>T non_coding_transcript_exon_variant 0.16
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.16
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.16
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.16
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.16
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.16
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.16
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.16
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.16
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.17
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.12
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.13
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.13
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 0.19
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.19
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.28
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.26
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.26
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.26
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.26
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.23
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.18
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.14
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.23
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.23
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.23
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.28
rrl 1475366 n.1709G>A non_coding_transcript_exon_variant 0.21
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.2
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.18
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.15
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.14
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.18
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.15
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.24
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.22
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.2
rrl 1475482 n.1825A>G non_coding_transcript_exon_variant 0.22
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.23
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.12
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.12
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.17
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.38
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.31
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.29
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.3
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.31
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.33
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.39
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.26
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 0.27
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.27
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.17
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.17
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.17
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.16
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.16
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.17
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.17
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.21
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.31
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.32
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.31
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.28
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.29
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.29
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.33
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.39
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.38
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.36
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.37
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.45
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.45
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.45
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.43
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.33
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.29
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.32
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.32
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.22
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.22
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.27
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.26
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.25
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.29
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.25
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.26
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.27
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.27
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.2
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.19
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.19
inhA 1674542 p.Ala114Glu missense_variant 0.12
rpsA 1833772 c.231C>T synonymous_variant 0.22
rpsA 1833778 c.237C>T synonymous_variant 0.22
rpsA 1833781 c.240T>G synonymous_variant 0.22
rpsA 1833790 c.249T>C synonymous_variant 0.2
rpsA 1833793 c.252C>T synonymous_variant 0.22
rpsA 1833802 c.261A>G synonymous_variant 0.24
rpsA 1833811 c.270G>T synonymous_variant 0.23
rpsA 1833817 c.276C>T synonymous_variant 0.24
rpsA 1833820 c.279G>A synonymous_variant 0.24
rpsA 1833832 c.291G>A synonymous_variant 0.22
rpsA 1833838 c.297G>T synonymous_variant 0.23
rpsA 1833841 c.300C>G synonymous_variant 0.22
rpsA 1833847 c.306C>G synonymous_variant 0.19
rpsA 1833856 c.315A>G synonymous_variant 0.2
rpsA 1833862 c.321G>T synonymous_variant 0.17
rpsA 1833874 c.333T>G synonymous_variant 0.22
rpsA 1833886 c.345C>G synonymous_variant 0.19
rpsA 1833892 c.351G>A synonymous_variant 0.19
rpsA 1833894 p.Ala118Glu missense_variant 0.21
rpsA 1833928 c.387G>C synonymous_variant 0.24
rpsA 1833949 c.408T>C synonymous_variant 0.21
rpsA 1833979 c.438T>C synonymous_variant 0.19
rpsA 1833991 c.450C>G synonymous_variant 0.2
rpsA 1834000 c.459G>C synonymous_variant 0.18
rpsA 1834012 c.471G>C synonymous_variant 0.17
rpsA 1834015 c.474G>C synonymous_variant 0.17
rpsA 1834021 c.480C>T synonymous_variant 0.17
rpsA 1834030 c.489C>G synonymous_variant 0.14
rpsA 1834069 c.528G>C synonymous_variant 0.15
rpsA 1834099 c.558C>G synonymous_variant 0.13
rpsA 1834108 c.567C>G synonymous_variant 0.12
rpsA 1834249 c.708T>C synonymous_variant 0.15
rpsA 1834261 c.720A>G synonymous_variant 0.15
rpsA 1834264 c.723G>C synonymous_variant 0.15
rpsA 1834345 c.804C>T synonymous_variant 0.12
rpsA 1834361 c.820T>C synonymous_variant 0.13
rpsA 1834366 c.825A>G synonymous_variant 0.13
rpsA 1834387 c.846C>T synonymous_variant 0.18
rpsA 1834396 c.855G>T synonymous_variant 0.22
rpsA 1834411 c.870T>C synonymous_variant 0.21
rpsA 1834432 c.891G>T synonymous_variant 0.18
rpsA 1834451 c.910T>C synonymous_variant 0.17
rpsA 1834456 c.915T>G synonymous_variant 0.17
rpsA 1834468 c.927A>G synonymous_variant 0.2
rpsA 1834489 c.948T>C synonymous_variant 0.15
rpsA 1834498 c.957C>T synonymous_variant 0.13
rpsA 1834513 c.972C>G synonymous_variant 0.17
rpsA 1834520 p.Ala327Ser missense_variant 0.15
rpsA 1834540 c.999G>C synonymous_variant 0.14
rpsA 1834543 c.1002C>G synonymous_variant 0.14
rpsA 1834546 c.1005T>C synonymous_variant 0.14
rpsA 1834555 c.1014T>C synonymous_variant 0.14
rpsA 1834556 p.Ala339Thr missense_variant 0.14
rpsA 1834654 p.Glu371Asp missense_variant 0.13
rpsA 1834690 c.1149T>C synonymous_variant 0.15
rpsA 1834699 p.Glu386Asp missense_variant 0.16
rpsA 1834700 p.Gln387Ala missense_variant 0.16
rpsA 1834733 p.Ala398Ser missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2517941 c.-174C>G upstream_gene_variant 0.23
kasA 2517962 c.-153C>G upstream_gene_variant 0.18
kasA 2517974 c.-141T>C upstream_gene_variant 0.16
thyA 3073806 c.666C>G synonymous_variant 0.23
thyA 3073868 p.Thr202Ala missense_variant 1.0
thyA 3073977 c.495A>G synonymous_variant 0.14
thyA 3073989 c.483T>C synonymous_variant 0.14
thyA 3073998 c.474G>A synonymous_variant 0.15
thyA 3074004 c.468T>C synonymous_variant 0.13
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339273 c.156T>G synonymous_variant 0.27
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
alr 3840719 c.702A>G synonymous_variant 1.0
rpoA 3877638 c.870T>C synonymous_variant 0.13
rpoA 3877644 c.864C>T synonymous_variant 0.16
rpoA 3877656 c.852T>G synonymous_variant 0.16
rpoA 3877668 c.840A>G synonymous_variant 0.17
rpoA 3877671 c.837C>G synonymous_variant 0.16
rpoA 3877677 c.831G>C synonymous_variant 0.17
rpoA 3877683 c.825G>C synonymous_variant 0.19
rpoA 3877686 c.822A>G synonymous_variant 0.19
rpoA 3877704 c.804G>T synonymous_variant 0.22
rpoA 3877728 c.780C>G synonymous_variant 0.22
rpoA 3877749 c.759C>T synonymous_variant 0.2
rpoA 3877770 c.738A>G synonymous_variant 0.16
rpoA 3877776 c.732T>C synonymous_variant 0.16
rpoA 3877782 c.726T>C synonymous_variant 0.17
rpoA 3877785 c.723C>G synonymous_variant 0.17
rpoA 3877794 c.714G>C synonymous_variant 0.14
rpoA 3877818 c.690A>G synonymous_variant 0.17
rpoA 3877839 c.669G>C synonymous_variant 0.17
rpoA 3877842 c.666A>G synonymous_variant 0.13
rpoA 3877848 c.660C>T synonymous_variant 0.14
rpoA 3877856 c.652T>C synonymous_variant 0.13
rpoA 3877872 c.636C>T synonymous_variant 0.17
rpoA 3877875 c.633T>G synonymous_variant 0.19
rpoA 3877881 c.627G>C synonymous_variant 0.2
rpoA 3877884 c.624G>C synonymous_variant 0.2
rpoA 3877893 c.615C>T synonymous_variant 0.22
rpoA 3877905 c.603A>C synonymous_variant 0.24
rpoA 3877908 c.600T>C synonymous_variant 0.22
rpoA 3877920 c.588G>C synonymous_variant 0.18
rpoA 3877926 c.582G>C synonymous_variant 0.19
rpoA 3878187 c.321C>G synonymous_variant 0.14
rpoA 3878193 c.315T>C synonymous_variant 0.15
rpoA 3878217 c.291A>G synonymous_variant 0.18
rpoA 3878626 c.-119A>C upstream_gene_variant 0.24
ddn 3986661 c.-183C>A upstream_gene_variant 0.2
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.17
ddn 3986681 c.-163C>G upstream_gene_variant 0.16
ddn 3986687 c.-157C>T upstream_gene_variant 0.14
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4038569 c.2136C>T synonymous_variant 0.14
clpC1 4038773 c.1932T>C synonymous_variant 0.14
clpC1 4038782 c.1923G>C synonymous_variant 0.19
clpC1 4038791 c.1914G>C synonymous_variant 0.18
clpC1 4038812 c.1893T>C synonymous_variant 0.22
clpC1 4038815 c.1890G>C synonymous_variant 0.24
clpC1 4038836 c.1869G>C synonymous_variant 0.25
clpC1 4038842 c.1863G>C synonymous_variant 0.24
clpC1 4038845 c.1858_1860delTCGinsAGT synonymous_variant 0.24
clpC1 4038857 c.1848C>A synonymous_variant 0.17
clpC1 4038860 c.1845G>C synonymous_variant 0.29
clpC1 4038878 c.1827A>G synonymous_variant 0.19
clpC1 4038923 c.1782A>G synonymous_variant 0.12
clpC1 4038932 c.1773G>A synonymous_variant 0.18
clpC1 4038941 c.1764G>C synonymous_variant 0.16
clpC1 4038953 c.1752A>G synonymous_variant 0.16
clpC1 4038965 c.1740T>C synonymous_variant 0.19
clpC1 4038971 c.1734T>C synonymous_variant 0.21
clpC1 4038974 c.1731T>C synonymous_variant 0.21
clpC1 4038995 c.1708_1710delTTGinsCTC synonymous_variant 0.22
clpC1 4039004 c.1701C>G synonymous_variant 0.24
clpC1 4039022 c.1683A>G synonymous_variant 0.23
clpC1 4039037 c.1668T>C synonymous_variant 0.19
clpC1 4039085 c.1620A>G synonymous_variant 0.16
clpC1 4039091 c.1614G>T synonymous_variant 0.17
clpC1 4039097 c.1608G>C synonymous_variant 0.17
clpC1 4039103 c.1602T>C synonymous_variant 0.14
clpC1 4039106 c.1599G>C synonymous_variant 0.14
clpC1 4039133 c.1572C>G synonymous_variant 0.11
clpC1 4039442 c.1263A>G synonymous_variant 0.16
clpC1 4039448 c.1257A>G synonymous_variant 0.18
clpC1 4039454 c.1251A>G synonymous_variant 0.2
clpC1 4039463 c.1242C>G synonymous_variant 0.14
clpC1 4039466 c.1239T>C synonymous_variant 0.14
clpC1 4039469 c.1236T>C synonymous_variant 0.13
clpC1 4039472 c.1233G>C synonymous_variant 0.13
clpC1 4039481 c.1224T>C synonymous_variant 0.14
clpC1 4039484 c.1221T>C synonymous_variant 0.15
clpC1 4039517 c.1188C>G synonymous_variant 0.15
clpC1 4039526 c.1179G>A synonymous_variant 0.19
clpC1 4039553 c.1152C>G synonymous_variant 0.17
clpC1 4039559 c.1146C>T synonymous_variant 0.19
clpC1 4039566 p.Val380Ala missense_variant 0.19
clpC1 4039568 p.Met379Ile missense_variant 0.19
clpC1 4039574 p.Ala377Gly missense_variant 0.2
clpC1 4039577 c.1128T>C synonymous_variant 0.2
clpC1 4039589 c.1116G>C synonymous_variant 0.19
clpC1 4039616 c.1089G>C synonymous_variant 0.19
clpC1 4039622 c.1083C>T synonymous_variant 0.16
clpC1 4039661 c.1044T>C synonymous_variant 0.12
clpC1 4039673 c.1032G>C synonymous_variant 0.12
clpC1 4039694 c.1011G>C synonymous_variant 0.17
clpC1 4039931 c.774T>C synonymous_variant 0.13
clpC1 4039937 c.768G>C synonymous_variant 0.13
clpC1 4039949 c.756G>C synonymous_variant 0.15
clpC1 4039955 c.750G>C synonymous_variant 0.17
clpC1 4039958 c.747G>C synonymous_variant 0.18
clpC1 4039979 c.726C>G synonymous_variant 0.22
clpC1 4039991 c.714G>C synonymous_variant 0.25
clpC1 4039994 p.Glu237Asp missense_variant 0.23
clpC1 4039997 c.708C>A synonymous_variant 0.24
clpC1 4040009 c.696C>G synonymous_variant 0.26
clpC1 4040018 c.687G>C synonymous_variant 0.26
clpC1 4040021 c.684A>C synonymous_variant 0.24
clpC1 4040024 c.681A>G synonymous_variant 0.25
clpC1 4040033 c.672G>C synonymous_variant 0.25
embC 4242422 p.Trp854Gly missense_variant 0.26
embC 4242425 p.Arg855Gly missense_variant 0.32
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243566 p.Asp112His missense_variant 0.98
aftB 4267601 c.1236C>G synonymous_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0