Run ID: SRR1049676
Sample name:
Date: 2024-10-04T11:35:29.529266
Number of reads: 2102991
Percentage reads mapped: 41.26
Median coverage: 46.0
Strain: lineage4.3.3;lineage4.8
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.3 | Euro-American (LAM) | None | 0.88 |
lineage4 | Euro-American | None | 1.0 |
lineage4.8 | Euro-American (mainly T) | RD219 | 0.07 |
lineage4.3.3 | Euro-American (LAM) | RD115 | 0.85 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Asp435Val | Assoc w R | |
isoniazid | katG | p.Ser315Thr | Assoc w R | High-level resistance |
ethambutol | embB | p.Gly406Ser | Assoc w R | |
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
capreomycin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
kanamycin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpoB | 761110 | p.Asp435Val | missense_variant | 0.76 | rifampicin | Assoc w R | |
rrs | 1473247 | n.1402C>A | non_coding_transcript_exon_variant | 0.65 | amikacin | Uncertain significance | Mutation from literature |
capreomycin | Uncertain significance | Mutation from literature | |||||
kanamycin | Uncertain significance | Mutation from literature | |||||
rrs | 1473329 | n.1484G>T | non_coding_transcript_exon_variant | 0.62 | amikacin | Assoc w R | |
capreomycin | Assoc w R | ||||||
kanamycin | Assoc w R | ||||||
katG | 2155168 | p.Ser315Thr | missense_variant | 0.9 | isoniazid | Assoc w R | High-level resistance |
embB | 4247729 | p.Gly406Ser | missense_variant | 0.94 | ethambutol | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 0.87 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8040 | p.Gly247Ser | missense_variant | 0.86 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 0.96 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 760997 | c.1191G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761013 | p.Val403Ile | missense_variant | 0.2 | rifampicin | |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761046 | p.Ile414Val | missense_variant | 0.23 | rifampicin | |
rpoB | 761051 | c.1245G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761084 | c.1278C>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761880 | p.Ala692Thr | missense_variant | 0.8 | rifampicin | Uncertain significance |
rpoB | 762475 | p.Gly890Ala | missense_variant | 0.11 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 762491 | c.2685T>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 762879 | p.Met1025Leu | missense_variant | 0.31 | rifampicin | Uncertain significance |
rpoB | 762887 | c.3081G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 762959 | c.3153G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>A | upstream_gene_variant | 0.32 | rifampicin | |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 763038 | p.Thr1078Ala | missense_variant | 0.12 | rifampicin | |
rpoC | 763058 | c.-312C>G | upstream_gene_variant | 0.13 | rifampicin | |
rpoB | 763075 | p.Thr1090Ile | missense_variant | 0.32 | rifampicin | |
rpoB | 763077 | p.Val1091Leu | missense_variant | 0.33 | rifampicin | |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 763126 | p.Pro1107Gln | missense_variant | 0.39 | rifampicin | |
rpoC | 763133 | c.-237G>C | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 763142 | c.-228C>G | upstream_gene_variant | 0.38 | rifampicin | |
rpoC | 763517 | p.Lys50Gln | missense_variant | 0.23 | rifampicin | |
rpoC | 763528 | c.159G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763532 | p.Thr55Ser | missense_variant | 0.25 | rifampicin | |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763550 | p.Tyr61Ala | missense_variant | 0.21 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763648 | c.279C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 763660 | c.291T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>T | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763711 | c.342G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763727 | p.Leu120Met | missense_variant | 0.41 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763751 | p.Ile128Val | missense_variant | 0.31 | rifampicin | |
rpoC | 764316 | p.Ala316Val | missense_variant | 0.31 | rifampicin | |
rpoC | 764344 | c.975C>T | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764371 | c.1002G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764387 | c.1018T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764455 | c.1086G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764593 | c.1224C>A | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764602 | c.1233C>T | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764605 | c.1236G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764626 | c.1257C>A | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 764662 | c.1293G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 764706 | p.Leu446Gln | missense_variant | 0.46 | rifampicin | Uncertain significance |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764722 | c.1353G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764737 | c.1368G>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764740 | p.Met457Ile | missense_variant | 0.16 | rifampicin | |
rpoC | 764746 | c.1377G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R |
rpoC | 765671 | p.Asp768Tyr | missense_variant | 0.86 | rifampicin | Uncertain significance |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.22 | streptomycin | |
rpsL | 781766 | c.207C>T | synonymous_variant | 0.24 | streptomycin | Not assoc w R - Interim |
rpsL | 781793 | c.234G>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781794 | p.Met79Leu | missense_variant | 0.29 | streptomycin | |
rpsL | 781802 | c.243G>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781805 | c.246G>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781814 | c.255C>T | synonymous_variant | 0.3 | streptomycin | |
rpsL | 781817 | c.258G>T | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781829 | c.270G>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781841 | c.282C>T | synonymous_variant | 0.24 | streptomycin | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472102 | n.257G>A | non_coding_transcript_exon_variant | 0.45 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.46 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.45 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472112 | n.267C>T | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472113 | n.268T>C | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472123 | n.278A>T | non_coding_transcript_exon_variant | 0.57 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.66 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472240 | n.395G>A | non_coding_transcript_exon_variant | 0.59 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472379 | n.534T>C | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472382 | n.537G>A | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472389 | n.544G>A | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472400 | n.555C>T | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472494 | n.649A>G | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472496 | n.651T>G | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472507 | n.662C>T | non_coding_transcript_exon_variant | 0.51 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472558 | n.713G>A | non_coding_transcript_exon_variant | 0.74 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472569 | n.724G>A | non_coding_transcript_exon_variant | 0.76 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472571 | n.726G>A | non_coding_transcript_exon_variant | 0.77 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472581 | n.736A>C | non_coding_transcript_exon_variant | 0.77 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472606 | n.761C>G | non_coding_transcript_exon_variant | 0.68 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472623 | n.778A>C | non_coding_transcript_exon_variant | 0.58 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472645 | n.800G>C | non_coding_transcript_exon_variant | 0.5 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472655 | n.810G>T | non_coding_transcript_exon_variant | 0.43 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472660 | n.815T>A | non_coding_transcript_exon_variant | 0.41 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472666 | n.821G>T | non_coding_transcript_exon_variant | 0.4 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472673 | n.828T>G | non_coding_transcript_exon_variant | 0.34 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472675 | n.830T>C | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472677 | n.832C>A | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472682 | n.837T>A | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472683 | n.838T>C | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472686 | n.841G>A | non_coding_transcript_exon_variant | 0.33 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472687 | n.842A>T | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472694 | n.849C>A | non_coding_transcript_exon_variant | 0.37 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472697 | n.852T>C | non_coding_transcript_exon_variant | 0.36 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472714 | n.869A>T | non_coding_transcript_exon_variant | 0.46 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472767 | n.922G>A | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.48 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472952 | n.1107T>C | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472955 | n.1110C>T | non_coding_transcript_exon_variant | 0.56 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.59 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472982 | n.1137G>A | non_coding_transcript_exon_variant | 0.62 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 0.6 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.6 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472993 | n.1148G>T | non_coding_transcript_exon_variant | 0.61 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.52 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.51 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.55 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473097 | n.1252G>A | non_coding_transcript_exon_variant | 0.58 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.55 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.55 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.53 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.55 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473122 | n.1277T>A | non_coding_transcript_exon_variant | 0.56 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473134 | n.1289T>C | non_coding_transcript_exon_variant | 0.6 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473147 | n.1302G>A | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473164 | n.1319C>T | non_coding_transcript_exon_variant | 0.63 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.63 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473226 | n.1381C>T | non_coding_transcript_exon_variant | 0.66 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473269 | n.1424C>T | non_coding_transcript_exon_variant | 0.65 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.65 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.64 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446_1447insT | non_coding_transcript_exon_variant | 0.66 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473319 | n.1474C>T | non_coding_transcript_exon_variant | 0.63 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473320 | n.1475G>A | non_coding_transcript_exon_variant | 0.62 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473324 | n.1479G>A | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | ||||||
rrl | 1473828 | n.173_174delTG | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1473834 | n.178_179insTAG | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1473844 | n.187C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473870 | n.213G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473871 | n.214T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473883 | n.226A>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1473887 | n.230T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473888 | n.231T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473890 | n.233T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473917 | n.260G>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1473922 | n.265A>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1474164 | n.507C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474166 | n.509G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474184 | n.527C>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474202 | n.545T>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474265 | n.608G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474466 | n.809G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474476 | n.819C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474488 | n.831G>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474496 | n.839C>A | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474497 | n.840G>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474506 | n.849C>G | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474507 | n.850G>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474558 | n.901G>A | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474583 | n.926C>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474601 | n.944C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474676 | n.1019T>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474770 | n.1113G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1474777 | n.1120T>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474779 | n.1122G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474782 | n.1125G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474783 | n.1126G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1474790 | n.1133C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>A | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474800 | n.1143T>C | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474827 | n.1170C>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>C | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474832 | n.1175A>T | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474905 | n.1248T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474920 | n.1263G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474988 | n.1331C>T | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475508 | n.1851A>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475536 | n.1879C>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475538 | n.1881T>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475539 | n.1882A>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475548 | n.1891C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475549 | n.1892T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475550 | n.1893A>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475692 | n.2035G>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475758 | n.2101_2102delACinsG | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1475768 | n.2111_2112delGTinsC | non_coding_transcript_exon_variant | 0.63 | capreomycin | |
linezolid | ||||||
rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1475896 | n.2239A>G | non_coding_transcript_exon_variant | 0.66 | capreomycin | |
linezolid | ||||||
rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475943 | n.2286G>A | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475952 | n.2295A>G | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475963 | n.2306G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475970 | n.2313C>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.65 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1475998 | n.2341C>T | non_coding_transcript_exon_variant | 0.59 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1476001 | n.2344T>C | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476025 | n.2368G>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476165 | n.2508T>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476256 | n.2599A>G | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.59 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476295 | n.2638C>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476296 | n.2639C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476298 | n.2641C>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476300 | n.2643G>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476309 | n.2652G>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476337 | n.2680C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.53 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476515 | n.2858C>T | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476524 | n.2867C>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476530 | n.2873C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476536 | n.2879G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476537 | n.2880A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476538 | n.2881A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476544 | n.2887T>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1476566 | n.2909A>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1476567 | n.2910C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476586 | n.2929C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.51 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476613 | n.2956G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>G | non_coding_transcript_exon_variant | 0.49 | capreomycin | |
linezolid | ||||||
rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476630 | n.2973A>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | |
linezolid | ||||||
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833724 | c.183C>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833734 | p.Ala65Ser | missense_variant | 0.24 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833781 | c.240T>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833782 | p.Ser81Ala | missense_variant | 0.43 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833794 | p.Glu85Gln | missense_variant | 0.44 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1833815 | p.Thr92Gln | missense_variant | 0.29 | pyrazinamide | |
rpsA | 1833829 | c.288A>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833832 | c.291G>A | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1834836 | p.Met432Thr | missense_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
tlyA | 1918526 | p.Gly196Glu | missense_variant | 0.89 | capreomycin | |
katG | 2154459 | c.1653C>T | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
pncA | 2289431 | c.-190G>T | upstream_gene_variant | 0.95 | pyrazinamide | |
kasA | 2518919 | p.Gly269Ser | missense_variant | 0.85 | isoniazid | |
Rv2477c | 2782561 | c.1482G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782582 | p.Asn487Glu | missense_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782585 | c.1458G>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782591 | c.1452T>A | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782594 | c.1449T>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782606 | p.Gly479Ser | missense_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782612 | c.1431T>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782621 | c.1422T>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782624 | c.1419G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
thyA | 3073868 | p.Thr202Ala | missense_variant | 0.81 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 0.9 | cycloserine | |
mtrB | 3625065 | p.Met517Leu | missense_variant | 0.89 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
clpC1 | 4038287 | c.2418C>T | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R |
clpC1 | 4039593 | p.Arg371Lys | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039634 | p.Glu357Asn | missense_variant | 0.25 | pyrazinamide | |
clpC1 | 4039691 | c.1014G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>A | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039711 | p.Ile332Phe | missense_variant | 0.28 | pyrazinamide | |
clpC1 | 4039714 | p.Tyr331His | missense_variant | 0.3 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039742 | c.963C>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039754 | c.951G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039929 | c.775_776delAGinsTC | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039937 | p.Val256Ile | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4039940 | c.765G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039949 | c.756G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039955 | c.750G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039960 | p.Thr249Ser | missense_variant | 0.27 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039994 | p.Glu237Asp | missense_variant | 0.39 | pyrazinamide | |
clpC1 | 4040000 | p.His235Lys | missense_variant | 0.33 | pyrazinamide | |
clpC1 | 4040003 | c.702G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040018 | c.687G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040057 | c.648C>A | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040063 | c.642G>C | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040066 | c.639G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040069 | c.636G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040083 | p.Thr208Ser | missense_variant | 0.21 | pyrazinamide | |
panD | 4044824 | c.-543C>G | upstream_gene_variant | 0.79 | pyrazinamide | |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 0.94 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407695 | p.Glu170Lys | missense_variant | 0.88 | streptomycin | Uncertain significance |
gid | 4407720 | c.483C>G | synonymous_variant | 0.9 | streptomycin | Not assoc w R - Interim |
gid | 4408156 | p.Leu16Arg | missense_variant | 0.88 | streptomycin | Not assoc w R |