Run ID: SRR7645901
Sample name:
Date: 2024-04-16T11:28:33.338063
Number of reads: 3759371
Percentage reads mapped: 73.71
Median coverage: 75.0
Strain: lineage2.2.1
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage2 | East-Asian | RD105 | 1.0 |
lineage2.2.1 | East-Asian (Beijing) | RD105;RD207;RD181 | 1.0 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Leu430Pro | Assoc w R | |
isoniazid | katG | p.Ser315Thr | Assoc w R | High-level resistance |
ethambutol | ||||
pyrazinamide | pncA | p.Ala134Val | Assoc w R | |
streptomycin | rpsL | p.Lys43Arg | Assoc w R | |
rrs | n.799C>T | Uncertain significance | Mutation from literature | |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
capreomycin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
kanamycin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
cycloserine | ||||
ethionamide | ethA | p.Gln347* | Assoc w R | |
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpoB | 761095 | p.Leu430Pro | missense_variant | 0.93 | rifampicin | Assoc w R | |
rpsL | 781687 | p.Lys43Arg | missense_variant | 1.0 | streptomycin | Assoc w R | |
rrs | 1472644 | n.799C>T | non_coding_transcript_exon_variant | 0.48 | streptomycin | Uncertain significance | Mutation from literature |
rrs | 1473247 | n.1402C>A | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance | Mutation from literature |
kanamycin | Uncertain significance | Mutation from literature | |||||
amikacin | Uncertain significance | Mutation from literature | |||||
rrs | 1473329 | n.1484G>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Assoc w R | |
amikacin | Assoc w R | ||||||
kanamycin | Assoc w R | ||||||
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
pncA | 2288841 | p.Ala134Val | missense_variant | 1.0 | pyrazinamide | Assoc w R | |
ethA | 4326435 | p.Gln347* | stop_gained | 0.97 | ethionamide | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
mshA | 575907 | p.Ala187Val | missense_variant | 1.0 | ethionamide | Not assoc w R |
isoniazid | Not assoc w R | |||||
ccsA | 620625 | p.Ile245Met | missense_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Uncertain significance | |||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 1.0 | ethionamide | Uncertain significance |
rpoB | 761147 | c.1341C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>G | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 761156 | c.1350G>C | synonymous_variant | 0.12 | rifampicin | |
rpoB | 761159 | c.1353G>T | synonymous_variant | 0.12 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.11 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.1 | rifampicin | Not assoc w R - Interim |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.11 | rifampicin | |
rpoB | 761600 | c.1794T>C | synonymous_variant | 0.12 | rifampicin | |
rpoB | 761603 | c.1797C>G | synonymous_variant | 0.12 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 762879 | p.Met1025Leu | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoB | 762923 | c.3117C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 762947 | c.-423C>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 762956 | c.-414G>C | upstream_gene_variant | 0.14 | rifampicin | |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763504 | c.135C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763507 | c.138G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763528 | c.159G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763531 | c.162G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R |
rpoC | 763534 | c.165T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763540 | c.171C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763551 | p.Tyr61Ser | missense_variant | 0.28 | rifampicin | |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763578 | p.Phe70Tyr | missense_variant | 0.19 | rifampicin | |
rpoC | 763621 | c.252C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763648 | c.279C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763652 | c.283_285delATCinsCG | frameshift_variant&missense_variant | 0.22 | rifampicin | |
rpoC | 763660 | c.291T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763672 | c.303C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763705 | c.336G>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763708 | c.339G>T | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764545 | c.1176C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764548 | c.1179G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764561 | p.Pro398Ala | missense_variant | 0.25 | rifampicin | |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764582 | p.Leu405Met | missense_variant | 0.32 | rifampicin | |
rpoC | 764605 | c.1236G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764635 | c.1266C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764673 | c.1305_1306insTTG | conservative_inframe_insertion | 0.23 | rifampicin | |
rpoC | 764676 | p.Leu436Arg | missense_variant | 0.23 | rifampicin | |
rpoC | 764678 | c.1310_1312delAGC | disruptive_inframe_deletion | 0.24 | rifampicin | |
rpoC | 764706 | p.Leu446Gln | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoC | 764713 | c.1344G>A | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766645 | p.Glu1092Asp | missense_variant | 1.0 | rifampicin | Not assoc w R |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776182 | p.Asp767Asn | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R | |||||
mmpS5 | 779615 | c.-710C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
Rv1129c | 1254144 | p.Thr131Pro | missense_variant | 0.98 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 0.99 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
sigE | 1364706 | c.294G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
Rv1258c | 1406760 | c.580_581insC | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
isoniazid | Uncertain significance | |||||
pyrazinamide | Uncertain significance | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472102 | n.257G>A | non_coding_transcript_exon_variant | 0.34 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.36 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.37 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472112 | n.267C>T | non_coding_transcript_exon_variant | 0.33 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472113 | n.268T>C | non_coding_transcript_exon_variant | 0.34 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.59 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.66 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472225 | n.380C>A | non_coding_transcript_exon_variant | 0.65 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Uncertain significance | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472338 | n.493A>G | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472379 | n.534T>C | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472382 | n.537G>A | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472400 | n.555C>T | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472422 | n.577T>C | non_coding_transcript_exon_variant | 0.2 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Uncertain significance | |||||
rrs | 1472494 | n.649A>G | non_coding_transcript_exon_variant | 0.36 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472496 | n.651T>A | non_coding_transcript_exon_variant | 0.37 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 0.4 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472558 | n.713G>A | non_coding_transcript_exon_variant | 0.69 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472569 | n.724G>A | non_coding_transcript_exon_variant | 0.69 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472570 | n.725G>A | non_coding_transcript_exon_variant | 0.22 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472581 | n.736A>T | non_coding_transcript_exon_variant | 0.68 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472584 | n.739A>T | non_coding_transcript_exon_variant | 0.68 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472607 | n.762G>A | non_coding_transcript_exon_variant | 0.66 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472655 | n.810G>T | non_coding_transcript_exon_variant | 0.44 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472660 | n.815T>C | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472673 | n.828T>G | non_coding_transcript_exon_variant | 0.14 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472674 | n.829T>G | non_coding_transcript_exon_variant | 0.12 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472675 | n.830T>A | non_coding_transcript_exon_variant | 0.12 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472677 | n.832C>A | non_coding_transcript_exon_variant | 0.14 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472692 | n.847T>C | non_coding_transcript_exon_variant | 0.24 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.46 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.54 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.38 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472952 | n.1107T>C | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472955 | n.1110C>T | non_coding_transcript_exon_variant | 0.6 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.6 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 0.68 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 0.66 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.66 | streptomycin | Uncertain significance |
kanamycin | Not assoc w R | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.62 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.56 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.58 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473093 | n.1248C>T | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473102 | n.1257C>T | non_coding_transcript_exon_variant | 0.45 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.44 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.44 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.43 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473115 | n.1270G>T | non_coding_transcript_exon_variant | 0.45 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.44 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473122 | n.1277T>A | non_coding_transcript_exon_variant | 0.44 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.51 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473147 | n.1302G>A | non_coding_transcript_exon_variant | 0.51 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473164 | n.1319C>T | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.51 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473252 | n.1407T>C | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance |
kanamycin | Not assoc w R | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.63 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473283 | n.1438T>C | non_coding_transcript_exon_variant | 0.62 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.59 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446_1447insT | non_coding_transcript_exon_variant | 0.59 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.59 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473315 | n.1470T>C | non_coding_transcript_exon_variant | 0.58 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.57 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473698 | n.41G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1473699 | n.42A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473719 | n.62G>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1473721 | n.64G>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1473722 | n.65G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1473744 | n.87T>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1473746 | n.89T>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1473747 | n.90C>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1473750 | n.93C>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1473753 | n.96A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1473756 | n.99G>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473757 | n.100T>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473823 | n.166T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1473833 | n.176G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1473836 | n.179A>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1473871 | n.214T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473887 | n.230T>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473888 | n.231T>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473923 | n.266C>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473924 | n.267A>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1474155 | n.498G>A | non_coding_transcript_exon_variant | 0.14 | capreomycin | |
linezolid | ||||||
rrl | 1474164 | n.507C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474202 | n.545T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474228 | n.571T>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474275 | n.618T>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474281 | n.624A>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474284 | n.631_633delCCT | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474293 | n.637_651delCCTCTCCGGAGGAGG | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474316 | n.659T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474348 | n.691C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474351 | n.694G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474353 | n.696A>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474384 | n.727C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474466 | n.809G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474488 | n.831G>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474498 | n.841G>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1474505 | n.848C>G | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474529 | n.872A>C | non_coding_transcript_exon_variant | 0.59 | capreomycin | |
linezolid | ||||||
rrl | 1474530 | n.873G>A | non_coding_transcript_exon_variant | 0.58 | capreomycin | |
linezolid | ||||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474539 | n.882C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1474540 | n.883T>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1474583 | n.926C>T | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474628 | n.971C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474641 | n.984G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474663 | n.1006C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474675 | n.1018C>A | non_coding_transcript_exon_variant | 0.14 | capreomycin | |
linezolid | ||||||
rrl | 1474676 | n.1019T>C | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474677 | n.1020A>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474692 | n.1035G>A | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474736 | n.1079C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474751 | n.1094G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474777 | n.1120T>C | non_coding_transcript_exon_variant | 0.51 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474779 | n.1122G>A | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474783 | n.1126G>A | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474827 | n.1170C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>C | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474905 | n.1248T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474932 | n.1275C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475515 | n.1858G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475531 | n.1874C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475539 | n.1882A>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475548 | n.1891C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1475549 | n.1892T>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1475649 | n.1992A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475655 | n.1998T>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475672 | n.2015C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475673 | n.2016T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475699 | n.2042C>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475722 | n.2065G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475753 | n.2096C>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475767 | n.2110_2112delGGTinsTC | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1475869 | n.2212C>A | non_coding_transcript_exon_variant | 0.77 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475916 | n.2259C>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475943 | n.2286G>A | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475952 | n.2295A>G | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475963 | n.2306G>A | non_coding_transcript_exon_variant | 0.69 | capreomycin | |
linezolid | ||||||
rrl | 1475970 | n.2313C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475978 | n.2321C>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.59 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1476001 | n.2344T>C | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476130 | n.2473G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476164 | n.2507A>G | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476165 | n.2508T>A | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.57 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476221 | n.2564T>C | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476250 | n.2593C>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476255 | n.2598A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476256 | n.2599A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476308 | n.2651G>T | non_coding_transcript_exon_variant | 0.12 | capreomycin | |
linezolid | ||||||
rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.13 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476312 | n.2655T>C | non_coding_transcript_exon_variant | 0.13 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476337 | n.2680C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.66 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476429 | n.2772A>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.58 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.54 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476515 | n.2858C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476524 | n.2867C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476530 | n.2873C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476536 | n.2879G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476538 | n.2881A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476547 | n.2890C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rpsA | 1833668 | p.Ile43Val | missense_variant | 0.12 | pyrazinamide | |
rpsA | 1833694 | c.153G>C | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1833922 | p.Lys127Asn | missense_variant | 0.16 | pyrazinamide | Uncertain significance |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834069 | c.528G>C | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834090 | c.549G>C | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1834105 | c.564C>T | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834114 | c.573G>C | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
thyX | 3067963 | c.-19_-18insAC | upstream_gene_variant | 0.96 | para-aminosalicylic_acid | |
thyX | 3067969 | c.-24G>T | upstream_gene_variant | 0.96 | para-aminosalicylic_acid | |
thyX | 3067970 | c.-25T>C | upstream_gene_variant | 0.97 | para-aminosalicylic_acid | |
thyA | 3074393 | c.73_78delGGAACC | conservative_inframe_deletion | 1.0 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612813 | p.Thr102Ala | missense_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
mtrB | 3626562 | p.Pro18Ser | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039940 | c.765G>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039949 | c.756G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039967 | p.Gln246His | missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039994 | p.Glu237Asp | missense_variant | 0.14 | pyrazinamide | |
clpC1 | 4040001 | p.His235Arg | missense_variant | 0.15 | pyrazinamide | |
clpC1 | 4040015 | c.690G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040030 | c.675C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040051 | c.654C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040069 | c.636G>C | synonymous_variant | 0.18 | pyrazinamide | |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4243460 | c.228C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
aftB | 4267647 | p.Asp397Gly | missense_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338563 | c.-42G>T | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
whiB6 | 4338594 | c.-73T>A | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407927 | p.Glu92Asp | missense_variant | 1.0 | streptomycin | Not assoc w R |