TB-Profiler result

Run: 8d207ed2-777d-45e4-b9c1-c2ee9463a875
Summary

Run ID: 8d207ed2-777d-45e4-b9c1-c2ee9463a875

Sample name:

Date: 14-02-2023 02:11:29

Number of reads: 6873639

Percentage reads mapped: 63.31

Median coverage: 151

Strain: lineage4.5

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.5 Euro-American RD122 0.99
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
moxifloxacin
levofloxacin
bedaquiline
delamanid
pretomanid
linezolid
streptomycin rrs n.888G>A Uncertain significance
amikacin
kanamycin
capreomycin
clofazimine
ethionamide
para-aminosalicylic_acid
cycloserine
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7362 p.Glu21Gln missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7892 c.591G>A synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9304 p.Gly668Asp missense_variant 0.99 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
mshA 576479 p.Pro378Ala missense_variant 0.14 ethionamide
isoniazid
ccsA 620029 c.139C>T synonymous_variant 1.0 capreomycin
amikacin
rpoB 761318 c.1512G>C synonymous_variant 0.11 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.1 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.11 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.11 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 0.11 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.12 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.13 rifampicin
rpoB 762239 c.2433G>A synonymous_variant 0.12 rifampicin
rpoB 762245 c.2439G>C synonymous_variant 0.13 rifampicin
rpoB 762284 c.2478G>T synonymous_variant 0.12 rifampicin
rpoB 762293 c.2487T>G synonymous_variant 0.12 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.1 rifampicin
rpoB 762314 c.2508C>A synonymous_variant 0.1 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.1 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.1 rifampicin
rpoC 762911 c.-459C>T upstream_gene_variant 0.15 rifampicin
rpoC 762920 c.-450C>T upstream_gene_variant 0.16 rifampicin
rpoC 762929 c.-441G>C upstream_gene_variant 0.17 rifampicin
rpoC 762959 c.-411G>C upstream_gene_variant 0.16 rifampicin
rpoC 762962 c.-408C>T upstream_gene_variant 0.14 rifampicin
rpoC 762983 c.-387C>T upstream_gene_variant 0.15 rifampicin
rpoC 762989 c.-381G>A upstream_gene_variant 0.16 rifampicin
rpoC 762995 c.-375G>T upstream_gene_variant 0.17 rifampicin
rpoC 763004 c.-366G>A upstream_gene_variant 0.15 rifampicin
rpoC 763007 c.-363C>T upstream_gene_variant 0.16 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.15 rifampicin
rpoC 763028 c.-342T>C upstream_gene_variant 0.15 rifampicin
rpoC 763053 c.-317T>C upstream_gene_variant 0.13 rifampicin
rpoC 763070 c.-300T>C upstream_gene_variant 0.14 rifampicin
rpoC 763076 c.-294C>G upstream_gene_variant 0.14 rifampicin
rpoC 763088 c.-282C>G upstream_gene_variant 0.16 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.15 rifampicin
rpoC 763115 c.-255T>C upstream_gene_variant 0.14 rifampicin
rpoC 763127 c.-243G>T upstream_gene_variant 0.12 rifampicin
rpoC 763130 c.-240G>A upstream_gene_variant 0.12 rifampicin
rpoC 763133 c.-237G>C upstream_gene_variant 0.12 rifampicin
rpoC 763136 c.-234C>T upstream_gene_variant 0.13 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.12 rifampicin
rpoC 763166 c.-204A>G upstream_gene_variant 0.11 rifampicin
rpoC 763169 c.-201A>G upstream_gene_variant 0.11 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.11 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.1 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.11 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.12 rifampicin
rpoC 763921 c.552G>C synonymous_variant 0.1 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.18 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.18 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.18 rifampicin
rpoC 764371 c.1002G>C synonymous_variant 0.15 rifampicin
rpoC 764374 c.1005C>T synonymous_variant 0.15 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.15 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 0.13 rifampicin
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.1 rifampicin
rpoC 764485 c.1116G>C synonymous_variant 0.11 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.13 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.12 rifampicin
rpoC 764500 c.1131C>G synonymous_variant 0.12 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.11 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.12 rifampicin
rpoC 764530 c.1161C>T synonymous_variant 0.12 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.14 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.14 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.2 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.17 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.16 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.17 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.17 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.16 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.17 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.13 rifampicin
rpoC 764692 c.1323C>T synonymous_variant 0.13 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 0.12 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.13 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.15 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.16 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.16 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.15 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.17 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.17 rifampicin
rpoC 764827 c.1458G>C synonymous_variant 0.16 rifampicin
rpoC 764851 c.1482C>T synonymous_variant 0.13 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.13 rifampicin
rpoC 764869 c.1500C>T synonymous_variant 0.14 rifampicin
rpoC 764875 c.1506C>T synonymous_variant 0.13 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.13 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.12 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.11 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.14 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.13 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 0.13 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.1 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.1 rifampicin
rpoC 765908 c.2539C>T synonymous_variant 0.11 rifampicin
rpoC 767020 c.3651C>G synonymous_variant 0.1 rifampicin
rpoC 767023 c.3654C>T synonymous_variant 0.1 rifampicin
rpoC 767068 c.3699G>T synonymous_variant 0.12 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.11 rifampicin
rpoC 767104 c.3735C>G synonymous_variant 0.1 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.12 rifampicin
rpoC 767134 c.3765C>T synonymous_variant 0.12 rifampicin
rpoC 767138 c.3769C>T synonymous_variant 0.13 rifampicin
rpoC 767162 p.Asn1265Ala missense_variant 0.11 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.13 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.13 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.13 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.11 rifampicin
rpoC 767197 c.3828G>A synonymous_variant 0.12 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776053 c.2428T>C synonymous_variant 0.12 clofazimine
bedaquiline
mmpL5 776075 c.2406C>G synonymous_variant 0.2 clofazimine
bedaquiline
mmpL5 776078 c.2403C>A synonymous_variant 0.16 clofazimine
bedaquiline
mmpL5 776084 c.2397C>G synonymous_variant 0.16 clofazimine
bedaquiline
mmpL5 776087 c.2394C>G synonymous_variant 0.2 clofazimine
bedaquiline
mmpL5 776090 c.2391C>T synonymous_variant 0.16 clofazimine
bedaquiline
mmpL5 776096 c.2385C>G synonymous_variant 0.2 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Leu missense_variant 0.22 clofazimine
bedaquiline
mmpL5 776107 c.2374C>T synonymous_variant 0.16 clofazimine
bedaquiline
mmpL5 776129 c.2352C>G synonymous_variant 0.13 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Uncertain significance
rpsL 781892 c.333A>G synonymous_variant 0.1 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.1 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.1 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.13 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.14 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.14 streptomycin Uncertain significance
Rv1258c 1406101 p.Pro414Ser missense_variant 1.0 streptomycin Uncertain significance
pyrazinamide Uncertain significance
isoniazid Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.32 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.32 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.33 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.32 linezolid
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.14 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.31 linezolid
kanamycin Uncertain significance
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.4 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.25 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.35 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.51 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.49 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.48 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.13 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.13 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.23 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.26 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.27 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.26 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.34 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.36 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.36 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.36 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.32 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.16 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.26 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.26 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.29 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.27 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.3 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.32 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.39 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.4 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.41 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.43 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.4 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.38 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.38 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.27 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.28 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.29 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.25 linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.26 linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.27 linezolid
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.24 linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 0.23 linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.22 linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1473830 n.173T>A non_coding_transcript_exon_variant 0.21 linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.22 linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.22 linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.16 linezolid
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.14 linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.14 linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.13 linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.14 linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.2 linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.2 linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.2 linezolid
rrl 1474102 n.445_446insTGAAC non_coding_transcript_exon_variant 0.2 linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.29 linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.28 linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.29 linezolid
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.29 linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.31 linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.14 linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.1 linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.11 linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.19 linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.21 linezolid
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.22 linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.22 linezolid
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.16 linezolid
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.16 linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.28 linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.41 linezolid
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.42 linezolid
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.44 linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.46 linezolid
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 0.28 linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.28 linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.38 linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.1 linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.13 linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.24 linezolid
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.34 linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.41 linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.35 linezolid
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.36 linezolid
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.3 linezolid
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.3 linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.35 linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.3 linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.3 linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.3 linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.3 linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.36 linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.35 linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.34 linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.35 linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.26 linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.34 linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.31 linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.31 linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.35 linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.39 linezolid
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.46 linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.48 linezolid
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.47 linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.49 linezolid
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.45 linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.43 linezolid
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.42 linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.41 linezolid
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.4 linezolid
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.4 linezolid Uncertain significance
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.13 linezolid
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.14 linezolid Uncertain significance
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.2 linezolid
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.27 linezolid
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.28 linezolid
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.35 linezolid
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.34 linezolid
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.34 linezolid
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.44 linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.42 linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.39 linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.35 linezolid
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.23 linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.23 linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.2 linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.15 linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.14 linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.14 linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.14 linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.15 linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.11 linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.1 linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.11 linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.1 linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.1 linezolid
fabG1 1673710 p.Leu91Ile missense_variant 0.1 ethionamide
isoniazid
fabG1 1673716 p.Ala93Gln missense_variant 0.1 ethionamide
isoniazid
inhA 1673721 c.-481C>T upstream_gene_variant 0.12 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.12 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.11 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.11 ethionamide
isoniazid
fabG1 1673760 p.Lys107Asn missense_variant 0.11 ethionamide
isoniazid
inhA 1673769 c.-433C>T upstream_gene_variant 0.1 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.1 ethionamide
isoniazid
inhA 1674839 p.Ala213Asp missense_variant 0.1 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.11 ethionamide
isoniazid
inhA 1674848 p.Gln216Arg missense_variant 0.11 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 0.13 ethionamide
isoniazid
inhA 1674876 c.675C>T synonymous_variant 0.11 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 0.11 ethionamide
isoniazid
inhA 1674883 p.Ile228Val missense_variant 0.11 ethionamide Uncertain significance
isoniazid Uncertain significance
rpsA 1833760 c.219C>T synonymous_variant 0.11 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.12 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.12 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.12 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.13 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.13 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.12 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.14 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.14 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.15 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.15 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.17 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.17 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.19 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.22 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.23 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.23 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.23 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.23 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.22 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.21 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.2 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.18 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.18 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.2 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.19 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.21 pyrazinamide
rpsA 1834067 c.526C>T synonymous_variant 0.21 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.16 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.16 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.13 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.14 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.16 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.17 pyrazinamide
rpsA 1834264 c.723G>C synonymous_variant 0.19 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.18 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.2 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.19 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.24 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.21 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.23 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.25 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.24 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.19 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.19 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.2 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.15 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.14 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.15 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.13 pyrazinamide
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.13 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.21 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.19 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.16 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.15 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.17 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.19 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.12 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin
PPE35 2170035 p.Val193Ala missense_variant 0.21 pyrazinamide
PPE35 2170048 p.Leu189Val missense_variant 0.38 pyrazinamide
PPE35 2170053 p.Thr187Ser missense_variant 0.37 pyrazinamide
PPE35 2170210 p.Ala135Pro missense_variant 0.21 pyrazinamide
PPE35 2170568 p.Ile15Met missense_variant 0.99 pyrazinamide
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
Rv2752c 3065058 c.1134C>G synonymous_variant 0.17 rifampicin
isoniazid
Rv2752c 3065061 c.1131C>T synonymous_variant 0.17 rifampicin
isoniazid
Rv2752c 3065064 c.1128G>C synonymous_variant 0.18 rifampicin
isoniazid
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 0.19 rifampicin
isoniazid
Rv2752c 3065088 c.1104A>G synonymous_variant 0.19 rifampicin
isoniazid
Rv2752c 3065109 c.1081_1083delAGAinsCGT synonymous_variant 0.16 rifampicin
isoniazid
Rv2752c 3065115 c.1077C>G synonymous_variant 0.16 rifampicin
isoniazid
Rv2752c 3065126 p.Ser356Ala missense_variant 0.12 rifampicin
isoniazid
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0 capreomycin
amikacin
rpoA 3877875 c.633T>C synonymous_variant 0.1 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.12 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.13 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.12 rifampicin
rpoA 3877908 c.600T>C synonymous_variant 0.13 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.12 rifampicin
rpoA 3877923 c.585C>T synonymous_variant 0.12 rifampicin
rpoA 3877926 c.582G>A synonymous_variant 0.13 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.12 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.12 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.1 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.1 rifampicin
rpoA 3878575 c.-68C>T upstream_gene_variant 0.99 rifampicin
rpoA 3878608 c.-101C>G upstream_gene_variant 0.29 rifampicin
clpC1 4038318 p.Pro796Leu missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4038878 c.1827A>G synonymous_variant 0.12 pyrazinamide
clpC1 4038884 c.1821C>T synonymous_variant 0.12 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.12 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.11 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.1 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.11 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.11 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.14 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.12 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.12 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.14 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.13 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.14 pyrazinamide
clpC1 4039064 c.1641C>G synonymous_variant 0.12 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.12 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.12 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.11 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.1 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.11 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.1 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.1 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.1 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.14 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.14 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 0.12 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.12 pyrazinamide
clpC1 4039280 c.1425G>T synonymous_variant 0.11 pyrazinamide
clpC1 4039283 c.1422C>T synonymous_variant 0.11 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.1 pyrazinamide
clpC1 4039979 c.726C>A synonymous_variant 0.11 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.12 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.1 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.1 pyrazinamide
embC 4240777 c.915G>A synonymous_variant 0.1 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.1 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.1 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.1 ethambutol
embA 4242643 c.-590C>T upstream_gene_variant 1.0 ethambutol
embB 4246544 p.Thr11Pro missense_variant 0.17 ethambutol Uncertain significance
embB 4246548 p.Pro12Gln missense_variant 0.2 ethambutol Uncertain significance
embB 4246555 c.42G>C synonymous_variant 0.16 ethambutol
embB 4246556 p.Ala15Pro missense_variant 0.16 ethambutol Uncertain significance
embB 4246563 p.Leu17Trp missense_variant 0.17 ethambutol Uncertain significance
embB 4246567 c.54G>T synonymous_variant 0.13 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 streptomycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance