Run ID: ERR4818851
Sample name:
Date: 2024-10-04T19:10:59.682673
Number of reads: 1168188
Percentage reads mapped: 43.37
Median coverage: 26.0
Strain: lineage4.4.1.1
Spoligotype:
Drug-resistance: RR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.4.1 | Euro-American (S-type) | None | 1.0 |
lineage4 | Euro-American | None | 1.0 |
lineage4.4.1.1 | Euro-American | None | 1.0 |
lineage4.4 | Euro-American | None | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Ser441Ala | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpoB | 761127 | p.Ser441Ala | missense_variant | 0.31 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
Rv0010c | 13452 | p.Gly36Val | missense_variant | 1.0 | isoniazid | Uncertain significance |
rpoB | 761054 | c.1248G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761058 | p.Val418Thr | missense_variant | 0.33 | rifampicin | |
rpoB | 761088 | c.1282_1283delAGinsTC | synonymous_variant | 0.39 | rifampicin | |
rpoB | 761096 | c.1290G>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.37 | rifampicin | |
rpoB | 761132 | c.1326G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761600 | c.1794T>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762197 | c.2391C>G | synonymous_variant | 0.34 | rifampicin | |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.44 | rifampicin | |
rpoB | 762212 | c.2406G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | p.Pro810Ser | missense_variant | 0.41 | rifampicin | |
rpoB | 762245 | c.2439G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 762248 | c.2442G>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 762863 | c.-507T>G | upstream_gene_variant | 0.25 | rifampicin | |
rpoB | 762879 | p.Met1025Leu | missense_variant | 0.43 | rifampicin | Uncertain significance |
rpoB | 762887 | c.3081G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 762896 | c.-474G>C | upstream_gene_variant | 0.47 | rifampicin | |
rpoC | 762926 | c.-444C>G | upstream_gene_variant | 0.46 | rifampicin | |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 762938 | c.-432G>C | upstream_gene_variant | 0.47 | rifampicin | |
rpoC | 762944 | c.-426C>T | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 763483 | c.114G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763492 | c.123G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 763507 | c.138G>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 763528 | c.159G>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 763531 | c.162G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R |
rpoC | 763534 | c.165T>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 763537 | c.168C>G | synonymous_variant | 0.66 | rifampicin | |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 763550 | p.Tyr61Ala | missense_variant | 0.65 | rifampicin | |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 763578 | p.Phe70Tyr | missense_variant | 0.54 | rifampicin | |
rpoC | 763585 | c.216C>G | synonymous_variant | 0.49 | rifampicin | |
rpoC | 763589 | p.Ile74Val | missense_variant | 0.48 | rifampicin | |
rpoC | 763606 | c.237C>A | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763615 | c.246G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 763618 | c.249C>T | synonymous_variant | 0.46 | rifampicin | |
rpoC | 763622 | p.Ala85Ser | missense_variant | 0.51 | rifampicin | Uncertain significance |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763647 | p.Gly93Ala | missense_variant | 0.59 | rifampicin | |
rpoC | 763655 | p.Glu96Lys | missense_variant | 0.57 | rifampicin | |
rpoC | 763660 | c.291T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763724 | p.Asp119Asn | missense_variant | 0.4 | rifampicin | |
rpoC | 763729 | c.360G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763751 | p.Ile128Val | missense_variant | 0.4 | rifampicin | |
rpoC | 763765 | c.396T>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764549 | p.Pro394Val | missense_variant | 0.3 | rifampicin | |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764572 | c.1203G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764582 | p.Leu405Met | missense_variant | 0.33 | rifampicin | |
rpoC | 764605 | c.1236G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764620 | c.1251G>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764623 | c.1254C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764635 | c.1266C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800632 | c.-177_-176delATinsTC | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800639 | c.-170C>G | upstream_gene_variant | 0.45 | linezolid | |
rplC | 800645 | c.-164C>G | upstream_gene_variant | 0.48 | linezolid | |
rplC | 800648 | c.-161A>G | upstream_gene_variant | 0.5 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800667 | c.-142_-140delTCGinsAGC | upstream_gene_variant | 0.42 | linezolid | |
rplC | 800672 | c.-137G>C | upstream_gene_variant | 0.42 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.34 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.25 | linezolid | |
Rv1129c | 1254427 | c.108G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.75 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472078 | n.233C>T | non_coding_transcript_exon_variant | 0.82 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.94 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472123 | n.278A>G | non_coding_transcript_exon_variant | 0.95 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472124 | n.279C>T | non_coding_transcript_exon_variant | 0.87 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472150 | n.305T>G | non_coding_transcript_exon_variant | 0.95 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472151 | n.306C>A | non_coding_transcript_exon_variant | 0.88 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472155 | n.310C>T | non_coding_transcript_exon_variant | 0.88 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.88 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472258 | n.413A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472259 | n.414C>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472285 | n.440A>G | non_coding_transcript_exon_variant | 0.85 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472549 | n.704G>A | non_coding_transcript_exon_variant | 0.94 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472581 | n.736A>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472584 | n.739A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.97 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.97 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472824 | n.979T>A | non_coding_transcript_exon_variant | 0.93 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472825 | n.980G>A | non_coding_transcript_exon_variant | 0.83 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472828 | n.983T>C | non_coding_transcript_exon_variant | 0.91 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.89 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.92 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472958 | n.1113A>G | non_coding_transcript_exon_variant | 0.95 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 0.96 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472974 | n.1129A>G | non_coding_transcript_exon_variant | 0.96 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472988 | n.1143T>C | non_coding_transcript_exon_variant | 0.95 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.95 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.97 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.97 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.91 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473148 | n.1303G>T | non_coding_transcript_exon_variant | 0.96 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473163 | n.1318C>A | non_coding_transcript_exon_variant | 0.96 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473173 | n.1328C>T | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473221 | n.1376C>T | non_coding_transcript_exon_variant | 0.91 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473262 | n.1417T>C | non_coding_transcript_exon_variant | 0.91 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473276 | n.1431A>C | non_coding_transcript_exon_variant | 0.86 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473283 | n.1438T>C | non_coding_transcript_exon_variant | 0.83 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473284 | n.1439A>T | non_coding_transcript_exon_variant | 0.82 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473287 | n.1442_1449delCCTCGGGAinsG | non_coding_transcript_exon_variant | 0.84 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>G | non_coding_transcript_exon_variant | 0.84 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473314 | n.1469A>G | non_coding_transcript_exon_variant | 0.88 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1473315 | n.1470T>C | non_coding_transcript_exon_variant | 0.88 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.88 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473319 | n.1474C>T | non_coding_transcript_exon_variant | 0.88 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473782 | n.125A>G | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1473783 | n.126A>G | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1473788 | n.131A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473797 | n.140G>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473807 | n.150T>C | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473811 | n.154C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1473822 | n.165delAinsTG | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473836 | n.179A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473840 | n.183A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474197 | n.540C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474200 | n.545delT | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474264 | n.607T>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1474266 | n.609T>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474275 | n.618T>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1474315 | n.658A>G | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1474351 | n.694G>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474355 | n.698A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474393 | n.736A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1474402 | n.745T>C | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474413 | n.757_776delCCCACACGCGCATACGCGCG | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1474437 | n.781_782delAA | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474448 | n.791T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474467 | n.810A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1474488 | n.831G>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474495 | n.838G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1474498 | n.841G>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1474505 | n.848C>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474508 | n.851C>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474527 | n.870T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474542 | n.885A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474634 | n.977T>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1474636 | n.979A>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474658 | n.1001A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1474663 | n.1006C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474676 | n.1019T>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474677 | n.1020A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474692 | n.1035G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474711 | n.1054_1060delGGTGTAAinsCGGGTTGT | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474734 | n.1077G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474753 | n.1096_1097delACinsG | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474903 | n.1246T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475031 | n.1374G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475059 | n.1403_1404insTA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475062 | n.1405A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475065 | n.1409_1411delCAA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475076 | n.1419_1422delCCTTinsGCCCTA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475080 | n.1425_1426delCC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475090 | n.1433A>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475104 | n.1447T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475114 | n.1457C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475124 | n.1467A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475171 | n.1514C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475172 | n.1515A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475696 | n.2039T>C | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475699 | n.2042C>T | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475703 | n.2046A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475751 | n.2094C>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | |
linezolid | ||||||
rrl | 1475754 | n.2097G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
linezolid | ||||||
rrl | 1475756 | n.2099T>C | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
linezolid | ||||||
rrl | 1475762 | n.2105G>C | non_coding_transcript_exon_variant | 0.71 | capreomycin | |
linezolid | ||||||
rrl | 1475762 | n.2105G>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475763 | n.2107_2108delAA | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1475774 | n.2117C>T | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
linezolid | ||||||
rrl | 1475777 | n.2120A>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475900 | n.2243A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475916 | n.2259C>G | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476164 | n.2507A>G | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476179 | n.2522C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
linezolid | ||||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.86 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476207 | n.2550T>C | non_coding_transcript_exon_variant | 0.86 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476221 | n.2564T>C | non_coding_transcript_exon_variant | 0.82 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476357 | n.2700T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.9 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.92 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476513 | n.2856G>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
linezolid | ||||||
rrl | 1476515 | n.2858C>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476523 | n.2866T>C | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476524 | n.2867C>A | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476528 | n.2871A>G | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476536 | n.2879G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476538 | n.2881A>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476600 | n.2943A>C | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476633 | n.2976A>G | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476664 | n.3007T>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
linezolid | ||||||
rrl | 1476668 | n.3011C>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | |
linezolid | ||||||
rrl | 1476675 | n.3018C>A | non_coding_transcript_exon_variant | 0.81 | capreomycin | |
linezolid | ||||||
rpsA | 1833641 | p.Asn34Asp | missense_variant | 0.3 | pyrazinamide | |
rpsA | 1833646 | c.105T>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833652 | c.111C>T | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833667 | c.126C>T | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833668 | p.Ile43Val | missense_variant | 0.47 | pyrazinamide | |
rpsA | 1833676 | c.135A>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833679 | c.138G>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1833685 | c.144G>T | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1833688 | c.147C>T | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1833694 | c.153G>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.69 | pyrazinamide | |
rpsA | 1833732 | p.Pro64Leu | missense_variant | 0.65 | pyrazinamide | |
rpsA | 1833736 | c.195C>T | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.68 | pyrazinamide | |
rpsA | 1833770 | p.Asn77Asp | missense_variant | 0.56 | pyrazinamide | |
rpsA | 1833776 | p.Val79Ile | missense_variant | 0.53 | pyrazinamide | |
rpsA | 1833781 | c.240T>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833893 | p.AlaLeu118ArgIle | missense_variant | 0.4 | pyrazinamide | |
rpsA | 1833905 | p.Lys122Glu | missense_variant | 0.35 | pyrazinamide | |
rpsA | 1833912 | p.Glu124Gly | missense_variant | 0.39 | pyrazinamide | |
rpsA | 1833915 | p.Ala125Val | missense_variant | 0.41 | pyrazinamide | Uncertain significance |
rpsA | 1833921 | p.Lys127Thr | missense_variant | 0.41 | pyrazinamide | |
rpsA | 1833926 | p.Thr129Ser | missense_variant | 0.5 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833952 | c.411C>T | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833955 | c.414G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833961 | c.420C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833994 | c.453G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834009 | c.468C>T | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1834012 | c.471G>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1834015 | c.474G>T | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1834024 | c.483G>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834034 | p.Ile165Val | missense_variant | 0.41 | pyrazinamide | |
rpsA | 1834040 | p.Lys167Arg | missense_variant | 0.4 | pyrazinamide | |
rpsA | 1834046 | p.Ile169Leu | missense_variant | 0.41 | pyrazinamide | |
rpsA | 1834054 | c.513C>G | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834063 | c.522C>T | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834213 | c.672G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834219 | c.678C>G | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834225 | c.684C>G | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834228 | c.687C>T | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834246 | c.705G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834285 | c.744G>C | synonymous_variant | 0.37 | pyrazinamide | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
ndh | 2102990 | p.Val18Ala | missense_variant | 1.0 | isoniazid | Not assoc w R |
delamanid | Uncertain significance | |||||
ethionamide | Uncertain significance | |||||
PPE35 | 2169840 | p.Gly258Asp | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3083 | 3448608 | c.105G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv3236c | 3612665 | p.Val151Ala | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
clpC1 | 4040015 | p.Ala230Ser | missense_variant | 0.24 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040045 | c.660C>G | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040051 | c.654C>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040057 | c.648C>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040063 | c.642G>C | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040066 | c.639G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4040069 | c.636G>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040090 | c.615T>C | synonymous_variant | 0.43 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040096 | c.609G>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4040110 | c.595C>A | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040114 | p.Ile197Met | missense_variant | 0.28 | pyrazinamide | |
clpC1 | 4040117 | c.588A>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040125 | p.Glu194Lys | missense_variant | 0.29 | pyrazinamide | |
embC | 4238963 | c.-900C>T | upstream_gene_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin |