TB-Profiler result

Run: ERR987765
Summary

Run ID: ERR987765

Sample name:

Date: 02-04-2023 13:23:57

Number of reads: 3753191

Percentage reads mapped: 87.28

Strain: lineage4.6.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.1 Euro-American (Uganda) T2 RD724 0.99
lineage4.6.1.1 Euro-American T2-Uganda RD724 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6190 c.951A>G synonymous_variant 0.18
gyrB 6196 c.957C>A synonymous_variant 0.14
gyrB 6208 c.969G>A synonymous_variant 0.15
gyrB 6214 c.975G>C synonymous_variant 0.16
gyrB 6223 c.984G>C synonymous_variant 0.15
gyrB 6229 c.990G>A synonymous_variant 0.15
gyrA 6622 c.-680C>T upstream_gene_variant 0.11
gyrA 6634 c.-668T>C upstream_gene_variant 0.12
gyrA 6649 c.-653T>G upstream_gene_variant 0.16
gyrB 6663 p.Phe475Tyr missense_variant 0.23
gyrA 6667 c.-635G>A upstream_gene_variant 0.24
gyrA 6673 c.-629A>T upstream_gene_variant 0.23
gyrA 6700 c.-602T>C upstream_gene_variant 0.16
gyrA 6703 c.-599G>C upstream_gene_variant 0.14
gyrA 6709 c.-593A>G upstream_gene_variant 0.16
gyrA 6712 c.-590G>C upstream_gene_variant 0.16
gyrA 6715 c.-587C>G upstream_gene_variant 0.16
gyrA 6722 c.-580C>A upstream_gene_variant 0.14
gyrA 6730 c.-572A>G upstream_gene_variant 0.15
gyrA 6742 c.-560A>G upstream_gene_variant 0.17
gyrA 6745 c.-557T>C upstream_gene_variant 0.15
gyrA 6760 c.-542G>C upstream_gene_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7442 c.141G>T synonymous_variant 0.13
gyrA 7472 c.171T>C synonymous_variant 0.12
gyrA 7475 c.174A>C synonymous_variant 0.13
gyrA 7484 c.183T>C synonymous_variant 0.14
gyrA 7514 c.213C>G synonymous_variant 0.12
gyrA 7523 c.222C>G synonymous_variant 0.15
gyrA 7526 c.225G>T synonymous_variant 0.15
gyrA 7532 c.231T>C synonymous_variant 0.14
gyrA 7539 p.Thr80Ala missense_variant 0.85
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7694 c.393A>G synonymous_variant 0.17
gyrA 7697 c.396C>G synonymous_variant 0.19
gyrA 7703 c.402G>C synonymous_variant 0.21
gyrA 7710 c.409_411delTTGinsCTC synonymous_variant 0.21
gyrA 7728 c.427_429delAGGinsCGT synonymous_variant 0.25
gyrA 7763 c.462T>G synonymous_variant 0.27
gyrA 7775 c.474C>T synonymous_variant 0.28
gyrA 7784 c.483A>G synonymous_variant 0.25
gyrA 7787 c.486G>A synonymous_variant 0.24
gyrA 7793 c.492G>C synonymous_variant 0.24
gyrA 7799 c.498A>G synonymous_variant 0.2
gyrA 7832 c.531G>C synonymous_variant 0.24
gyrA 7835 c.534A>C synonymous_variant 0.24
gyrA 7841 c.540C>T synonymous_variant 0.22
gyrA 7847 c.546G>C synonymous_variant 0.24
gyrA 7853 c.552C>G synonymous_variant 0.23
gyrA 7859 c.558A>G synonymous_variant 0.22
gyrA 7865 c.564T>C synonymous_variant 0.23
gyrA 7886 c.585T>C synonymous_variant 0.18
gyrA 7889 c.588G>A synonymous_variant 0.19
gyrA 7892 c.591G>C synonymous_variant 0.18
gyrA 7898 p.Asp199Glu missense_variant 0.2
gyrA 7906 p.Phe202Tyr missense_variant 0.2
gyrA 7919 p.Glu206Asp missense_variant 0.13
gyrA 8324 c.1023T>C synonymous_variant 0.18
gyrA 8327 c.1026C>T synonymous_variant 0.18
gyrA 8339 c.1038A>G synonymous_variant 0.19
gyrA 8366 c.1065G>C synonymous_variant 0.15
gyrA 8382 p.Leu361Met missense_variant 0.18
gyrA 8391 p.Tyr364His missense_variant 0.14
gyrA 8399 c.1098T>C synonymous_variant 0.13
gyrA 8408 c.1107A>G synonymous_variant 0.13
gyrA 8453 c.1152A>C synonymous_variant 0.14
gyrA 8585 c.1284C>T synonymous_variant 0.11
gyrA 8996 c.1695T>C synonymous_variant 0.14
gyrA 8998 p.Leu566Trp missense_variant 0.12
gyrA 9023 c.1722A>C synonymous_variant 0.12
gyrA 9029 c.1728T>G synonymous_variant 0.15
gyrA 9051 c.1750T>C synonymous_variant 0.18
gyrA 9056 c.1755C>G synonymous_variant 0.17
gyrA 9062 c.1761C>T synonymous_variant 0.17
gyrA 9065 c.1764C>G synonymous_variant 0.17
gyrA 9068 c.1767G>C synonymous_variant 0.17
gyrA 9071 c.1770G>C synonymous_variant 0.17
gyrA 9080 c.1779G>C synonymous_variant 0.16
gyrA 9089 c.1788G>C synonymous_variant 0.13
gyrA 9304 p.Gly668Asp missense_variant 0.99
fgd1 491316 c.534C>G synonymous_variant 0.16
fgd1 491321 p.Ala180Val missense_variant 0.16
fgd1 491343 c.561C>T synonymous_variant 0.16
fgd1 491349 c.567T>C synonymous_variant 0.16
fgd1 491355 c.573C>A synonymous_variant 0.2
fgd1 491364 c.582T>C synonymous_variant 0.15
fgd1 491367 c.585G>A synonymous_variant 0.14
fgd1 491370 c.588C>G synonymous_variant 0.14
fgd1 491563 p.Ser261Cys missense_variant 0.12
rpoB 760091 c.285G>C synonymous_variant 0.13
rpoB 760092 p.Ser96Thr missense_variant 0.13
rpoB 760101 c.295T>C synonymous_variant 0.13
rpoB 760106 c.300G>C synonymous_variant 0.15
rpoB 760112 c.306T>C synonymous_variant 0.15
rpoB 760118 c.312T>G synonymous_variant 0.16
rpoB 760121 c.315T>C synonymous_variant 0.16
rpoB 760130 c.324T>C synonymous_variant 0.17
rpoB 760139 c.333A>G synonymous_variant 0.15
rpoB 760142 c.336C>G synonymous_variant 0.14
rpoB 760148 p.Asp114Glu missense_variant 0.15
rpoB 760172 c.366G>C synonymous_variant 0.15
rpoB 760181 c.375T>C synonymous_variant 0.14
rpoB 760184 c.378A>G synonymous_variant 0.15
rpoB 760196 c.390C>G synonymous_variant 0.17
rpoB 760208 p.Ile134Met missense_variant 0.15
rpoB 760223 c.417T>C synonymous_variant 0.14
rpoB 760235 c.429T>C synonymous_variant 0.14
rpoB 760265 p.Met153Ile missense_variant 0.12
rpoB 760406 c.600G>C synonymous_variant 0.12
rpoB 760415 c.609C>T synonymous_variant 0.18
rpoB 760424 c.618C>G synonymous_variant 0.19
rpoB 760430 c.624T>C synonymous_variant 0.2
rpoB 760457 c.651C>G synonymous_variant 0.23
rpoB 760475 c.669A>G synonymous_variant 0.23
rpoB 760481 c.675G>C synonymous_variant 0.23
rpoB 760484 c.678A>G synonymous_variant 0.21
rpoB 760485 p.Pro227Ser missense_variant 0.21
rpoB 760511 c.705G>C synonymous_variant 0.16
rpoB 760611 c.805T>C synonymous_variant 0.16
rpoB 760616 p.Asp270Glu missense_variant 0.15
rpoB 760643 c.837G>A synonymous_variant 0.16
rpoB 760646 c.840C>G synonymous_variant 0.15
rpoB 760655 c.849A>G synonymous_variant 0.16
rpoB 760661 c.855A>C synonymous_variant 0.15
rpoB 760668 p.Thr288Ala missense_variant 0.14
rpoB 760674 c.868T>C synonymous_variant 0.13
rpoB 760683 c.877T>C synonymous_variant 0.13
rpoB 760841 c.1035T>C synonymous_variant 0.12
rpoB 760845 p.Thr347Val missense_variant 0.12
rpoB 760858 p.Val351Ala missense_variant 0.16
rpoB 760862 c.1056G>C synonymous_variant 0.16
rpoB 760869 p.Val355Phe missense_variant 0.17
rpoB 760883 c.1077G>C synonymous_variant 0.16
rpoB 760886 c.1080A>G synonymous_variant 0.16
rpoB 760887 p.Thr361Val missense_variant 0.17
rpoB 760916 c.1110C>T synonymous_variant 0.19
rpoB 760925 c.1119T>C synonymous_variant 0.18
rpoB 760928 c.1122G>C synonymous_variant 0.19
rpoB 760934 c.1128C>T synonymous_variant 0.18
rpoB 760946 c.1140A>G synonymous_variant 0.24
rpoB 760964 c.1158C>G synonymous_variant 0.25
rpoB 760965 p.Met387Leu missense_variant 0.25
rpoB 760970 c.1164G>C synonymous_variant 0.26
rpoB 760985 c.1179G>T synonymous_variant 0.29
rpoB 760991 c.1185G>C synonymous_variant 0.27
rpoB 761015 c.1209G>C synonymous_variant 0.28
rpoB 761027 c.1221A>G synonymous_variant 0.27
rpoB 761036 c.1230G>C synonymous_variant 0.22
rpoB 761037 c.1231T>C synonymous_variant 0.23
rpoB 761051 c.1245G>C synonymous_variant 0.22
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.14
rpoB 761102 c.1296A>G synonymous_variant 0.14
rpoB 761129 c.1323G>C synonymous_variant 0.15
rpoB 761133 c.1327T>C synonymous_variant 0.15
rpoB 761150 c.1344A>G synonymous_variant 0.15
rpoB 761282 c.1476C>G synonymous_variant 0.12
rpoB 761300 c.1494G>C synonymous_variant 0.14
rpoB 761600 c.1794T>C synonymous_variant 0.12
rpoB 761606 c.1800C>G synonymous_variant 0.13
rpoB 761615 c.1809A>G synonymous_variant 0.13
rpoB 761627 c.1821C>T synonymous_variant 0.12
rpoB 762014 c.2208C>T synonymous_variant 0.12
rpoB 762083 c.2277T>C synonymous_variant 0.12
rpoB 762086 c.2280G>C synonymous_variant 0.12
rpoB 762101 c.2295C>G synonymous_variant 0.13
rpoB 762170 c.2364C>G synonymous_variant 0.13
rpoB 762254 c.2448T>C synonymous_variant 0.12
rpoB 762293 c.2487T>C synonymous_variant 0.15
rpoB 762314 c.2508C>G synonymous_variant 0.14
rpoB 762317 c.2511A>G synonymous_variant 0.14
rpoC 762857 c.-513C>G upstream_gene_variant 0.15
rpoC 762860 c.-510G>C upstream_gene_variant 0.15
rpoC 762863 c.-507T>C upstream_gene_variant 0.16
rpoC 762929 c.-441G>C upstream_gene_variant 0.23
rpoC 762983 c.-387C>T upstream_gene_variant 0.17
rpoC 762995 c.-375G>T upstream_gene_variant 0.15
rpoC 763028 c.-342T>C upstream_gene_variant 0.12
rpoC 763031 c.-339T>G upstream_gene_variant 0.12
rpoC 763040 c.-330C>G upstream_gene_variant 0.16
rpoC 763053 c.-317T>C upstream_gene_variant 0.14
rpoC 763058 c.-312C>G upstream_gene_variant 0.12
rpoC 763070 c.-300T>C upstream_gene_variant 0.15
rpoC 763076 c.-294C>G upstream_gene_variant 0.16
rpoC 763082 c.-288C>G upstream_gene_variant 0.16
rpoC 763085 c.-285C>G upstream_gene_variant 0.15
rpoC 763094 c.-276G>C upstream_gene_variant 0.15
rpoC 763103 c.-267G>C upstream_gene_variant 0.16
rpoC 763115 c.-255T>G upstream_gene_variant 0.13
rpoC 763127 c.-243G>C upstream_gene_variant 0.12
rpoC 763133 c.-237G>C upstream_gene_variant 0.14
rpoC 763166 c.-204A>G upstream_gene_variant 0.15
rpoC 763169 c.-201A>G upstream_gene_variant 0.14
rpoC 763202 c.-168A>C upstream_gene_variant 0.12
rpoC 763205 c.-165G>C upstream_gene_variant 0.12
rpoC 763208 c.-162T>C upstream_gene_variant 0.13
rpoC 763430 c.61A>C synonymous_variant 0.12
rpoC 763468 c.99G>C synonymous_variant 0.19
rpoC 763486 c.117T>C synonymous_variant 0.17
rpoC 763489 c.120G>A synonymous_variant 0.17
rpoC 763492 c.123G>C synonymous_variant 0.18
rpoC 763546 c.177A>G synonymous_variant 0.22
rpoC 763597 c.228G>A synonymous_variant 0.13
rpoC 763606 c.237C>T synonymous_variant 0.12
rpoC 763609 c.240C>G synonymous_variant 0.12
rpoC 763615 c.246G>C synonymous_variant 0.12
rpoC 763618 c.249C>T synonymous_variant 0.12
rpoC 763633 c.264T>C synonymous_variant 0.12
rpoC 763660 c.291T>G synonymous_variant 0.12
rpoC 763696 c.327T>C synonymous_variant 0.14
rpoC 763732 c.363C>G synonymous_variant 0.14
rpoC 763744 c.375G>C synonymous_variant 0.16
rpoC 763765 c.396T>C synonymous_variant 0.15
rpoC 763782 p.Ser138Trp missense_variant 0.12
rpoC 764044 c.675T>C synonymous_variant 0.14
rpoC 764059 c.690G>C synonymous_variant 0.15
rpoC 764060 p.Pro231Ile missense_variant 0.16
rpoC 764083 c.714A>G synonymous_variant 0.18
rpoC 764098 c.729A>G synonymous_variant 0.23
rpoC 764102 p.Val245Ile missense_variant 0.24
rpoC 764134 c.765C>G synonymous_variant 0.15
rpoC 764140 c.771C>T synonymous_variant 0.12
rpoC 764236 c.867G>A synonymous_variant 0.13
rpoC 764257 c.888G>C synonymous_variant 0.15
rpoC 764266 c.897T>C synonymous_variant 0.15
rpoC 764278 c.909A>G synonymous_variant 0.13
rpoC 764284 c.915G>C synonymous_variant 0.14
rpoC 764338 c.969G>A synonymous_variant 0.17
rpoC 764347 c.978G>C synonymous_variant 0.14
rpoC 764365 c.996C>T synonymous_variant 0.12
rpoC 764428 c.1059G>C synonymous_variant 0.15
rpoC 764431 c.1062G>C synonymous_variant 0.14
rpoC 764434 c.1065A>G synonymous_variant 0.14
rpoC 764435 c.1066A>C synonymous_variant 0.14
rpoC 764443 p.Ile358Met missense_variant 0.14
rpoC 764458 c.1089G>C synonymous_variant 0.14
rpoC 764461 c.1092A>G synonymous_variant 0.13
rpoC 764539 c.1170C>G synonymous_variant 0.14
rpoC 764548 c.1179G>C synonymous_variant 0.13
rpoC 764560 c.1191T>C synonymous_variant 0.14
rpoC 764566 c.1197C>G synonymous_variant 0.14
rpoC 764575 c.1206T>G synonymous_variant 0.17
rpoC 764581 c.1212T>C synonymous_variant 0.19
rpoC 764626 c.1257C>T synonymous_variant 0.19
rpoC 764644 c.1275G>C synonymous_variant 0.19
rpoC 764650 c.1281G>T synonymous_variant 0.19
rpoC 764656 c.1287C>G synonymous_variant 0.2
rpoC 764695 c.1326T>C synonymous_variant 0.2
rpoC 764701 c.1332C>G synonymous_variant 0.2
rpoC 764713 c.1344G>A synonymous_variant 0.16
rpoC 764716 c.1347G>C synonymous_variant 0.15
rpoC 764746 c.1377G>C synonymous_variant 0.22
rpoC 764752 c.1383G>C synonymous_variant 0.21
rpoC 764758 c.1389C>G synonymous_variant 0.21
rpoC 764764 c.1395T>C synonymous_variant 0.19
rpoC 764791 c.1422C>G synonymous_variant 0.13
rpoC 764803 c.1434C>T synonymous_variant 0.14
rpoC 764809 c.1440C>T synonymous_variant 0.14
rpoC 764812 c.1443C>G synonymous_variant 0.15
rpoC 764815 c.1446A>G synonymous_variant 0.14
rpoC 764824 c.1455T>C synonymous_variant 0.14
rpoC 764827 c.1458G>C synonymous_variant 0.12
rpoC 765435 p.His689Pro missense_variant 0.85
rpoC 765454 c.2085C>G synonymous_variant 0.2
rpoC 765466 c.2097C>T synonymous_variant 0.19
rpoC 765478 c.2109T>C synonymous_variant 0.2
rpoC 765493 c.2124G>C synonymous_variant 0.21
rpoC 765544 c.2175C>G synonymous_variant 0.13
rpoC 765547 c.2178C>T synonymous_variant 0.13
rpoC 765548 c.2179_2180delAGinsTC synonymous_variant 0.13
rpoC 765553 c.2184C>G synonymous_variant 0.13
rpoC 765556 c.2187G>C synonymous_variant 0.13
rpoC 765559 c.2190G>C synonymous_variant 0.13
rpoC 765772 c.2403C>G synonymous_variant 0.14
rpoC 765781 p.Asp804Glu missense_variant 0.14
rpoC 765796 c.2427C>T synonymous_variant 0.15
rpoC 765811 c.2442T>C synonymous_variant 0.13
rpoC 765814 c.2445A>C synonymous_variant 0.13
rpoC 765823 c.2454C>G synonymous_variant 0.15
rpoC 765826 c.2457T>G synonymous_variant 0.15
rpoC 765850 c.2481G>C synonymous_variant 0.17
rpoC 765875 p.Val836Ile missense_variant 0.18
rpoC 765886 c.2517C>G synonymous_variant 0.16
rpoC 765892 c.2523T>C synonymous_variant 0.16
rpoC 765898 c.2529C>T synonymous_variant 0.16
rpoC 765934 c.2565C>T synonymous_variant 0.15
rpoC 765937 c.2568T>C synonymous_variant 0.15
rpoC 765940 c.2571A>T synonymous_variant 0.15
rpoC 765946 c.2577C>T synonymous_variant 0.13
rpoC 765947 c.2578T>C synonymous_variant 0.14
rpoC 765967 c.2598C>G synonymous_variant 0.15
rpoC 766381 c.3012C>T synonymous_variant 0.14
rpoC 766384 c.3015A>G synonymous_variant 0.15
rpoC 766390 c.3021C>T synonymous_variant 0.15
rpoC 766426 c.3057C>T synonymous_variant 0.16
rpoC 766447 c.3078T>C synonymous_variant 0.14
rpoC 766456 c.3087C>G synonymous_variant 0.16
rpoC 766486 c.3117A>G synonymous_variant 0.13
rpoC 766492 c.3123T>C synonymous_variant 0.13
rpoC 766495 c.3126C>T synonymous_variant 0.13
rpoC 766517 p.Thr1050Ser missense_variant 0.12
rpoC 766522 c.3153C>T synonymous_variant 0.12
rpoC 766525 c.3156G>C synonymous_variant 0.12
rpoC 766526 p.Val1053Ile missense_variant 0.12
rpoC 766534 c.3165C>G synonymous_variant 0.13
rpoC 766540 p.Asp1057Glu missense_variant 0.14
rpoC 766542 p.Gly1058Asp missense_variant 0.14
rpoC 766714 c.3345G>C synonymous_variant 0.12
rpoC 766726 c.3357T>C synonymous_variant 0.12
rpoC 766738 c.3369G>C synonymous_variant 0.14
rpoC 766765 c.3396A>C synonymous_variant 0.19
rpoC 766774 c.3405T>C synonymous_variant 0.2
rpoC 766775 p.Arg1136Lys missense_variant 0.2
rpoC 766804 c.3435A>G synonymous_variant 0.18
rpoC 766813 c.3444G>C synonymous_variant 0.17
rpoC 766963 c.3594T>C synonymous_variant 0.12
rpoC 766972 c.3603G>C synonymous_variant 0.17
rpoC 766996 c.3627C>G synonymous_variant 0.21
rpoC 767002 c.3633G>C synonymous_variant 0.24
rpoC 767011 c.3642G>C synonymous_variant 0.25
rpoC 767035 c.3666G>C synonymous_variant 0.2
rpoC 767044 c.3675G>C synonymous_variant 0.2
rpoC 767059 c.3690T>C synonymous_variant 0.14
rpoC 767062 c.3693C>G synonymous_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800693 c.-116A>G upstream_gene_variant 0.15
rplC 800703 c.-106T>C upstream_gene_variant 0.14
rplC 801249 c.441T>C synonymous_variant 0.13
rplC 801252 c.444G>C synonymous_variant 0.13
fbiC 1304403 c.1473T>C synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.21
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.21
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.2
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.21
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 0.21
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.12
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.12
rrs 1472033 n.188A>T non_coding_transcript_exon_variant 0.12
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.12
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.13
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.2
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.21
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.25
rrs 1472106 n.261G>T non_coding_transcript_exon_variant 0.3
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.31
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.23
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.29
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.29
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.27
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.28
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.29
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.3
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.13
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.13
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.13
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.27
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.39
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.36
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.36
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.35
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.33
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.29
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.26
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.26
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.24
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.22
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.22
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.21
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.15
rrl 1473677 n.20C>T non_coding_transcript_exon_variant 0.18
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.23
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.23
rrl 1473758 n.101G>A non_coding_transcript_exon_variant 0.24
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.12
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.12
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.14
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.14
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.17
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.17
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.18
rrl 1473937 n.280C>G non_coding_transcript_exon_variant 0.18
rrl 1473941 n.284T>C non_coding_transcript_exon_variant 0.17
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.16
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.16
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.16
rrl 1473965 n.308G>T non_coding_transcript_exon_variant 0.12
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.21
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.22
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.2
rrl 1474105 n.448T>C non_coding_transcript_exon_variant 0.19
rrl 1474106 n.449A>G non_coding_transcript_exon_variant 0.18
rrl 1474107 n.450T>G non_coding_transcript_exon_variant 0.18
rrl 1474109 n.452A>G non_coding_transcript_exon_variant 0.18
rrl 1474110 n.453A>T non_coding_transcript_exon_variant 0.18
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.27
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.27
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.28
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.29
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.29
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.33
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.33
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.21
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.12
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.13
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.12
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.12
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.28
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.28
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.28
rrl 1474498 n.841G>A non_coding_transcript_exon_variant 0.27
rrl 1474505 n.848C>T non_coding_transcript_exon_variant 0.28
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.3
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.3
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.29
rrl 1474712 n.1055G>T non_coding_transcript_exon_variant 0.16
rrl 1474715 n.1061delA non_coding_transcript_exon_variant 0.16
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.28
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.32
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.36
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.38
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.33
rrl 1475030 n.1373_1374insT non_coding_transcript_exon_variant 0.12
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.21
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.23
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.18
rrl 1475217 n.1560T>A non_coding_transcript_exon_variant 0.16
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.14
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.15
rrl 1475430 n.1773T>A non_coding_transcript_exon_variant 0.15
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 0.24
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.27
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.35
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.46
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.39
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.33
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.34
rrl 1475586 n.1929C>A non_coding_transcript_exon_variant 0.19
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.12
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.43
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.43
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.29
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.3
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.3
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.3
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.3
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.33
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.42
rrl 1476085 n.2428G>A non_coding_transcript_exon_variant 0.33
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.33
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.33
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.33
rrl 1476105 n.2448G>C non_coding_transcript_exon_variant 0.3
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.3
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.31
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.35
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.38
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.35
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.35
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.4
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.4
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.36
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.37
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 0.38
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.35
rrl 1476540 n.2883C>A non_coding_transcript_exon_variant 0.37
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.3
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.28
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.38
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.29
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.28
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.28
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.28
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.24
rrl 1476691 n.3034T>C non_coding_transcript_exon_variant 0.24
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.24
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.24
inhA 1674503 p.Thr101Ser missense_variant 0.13
inhA 1674507 c.306G>C synonymous_variant 0.14
inhA 1674513 c.312C>G synonymous_variant 0.15
inhA 1674514 p.Ile105Val missense_variant 0.15
inhA 1674534 c.333G>C synonymous_variant 0.21
inhA 1674542 p.Ala114Glu missense_variant 0.22
inhA 1674546 c.345T>C synonymous_variant 0.21
inhA 1674549 c.348G>C synonymous_variant 0.17
inhA 1674550 p.Ser117Ala missense_variant 0.17
inhA 1674573 c.372G>C synonymous_variant 0.18
inhA 1674576 c.375T>C synonymous_variant 0.19
inhA 1674585 c.384T>G synonymous_variant 0.24
inhA 1674589 p.Met130Leu missense_variant 0.24
inhA 1674601 p.Leu134Val missense_variant 0.21
inhA 1674610 p.Ile137Val missense_variant 0.19
inhA 1674621 c.420C>G synonymous_variant 0.21
inhA 1674624 c.423A>C synonymous_variant 0.19
inhA 1674630 c.429C>G synonymous_variant 0.17
inhA 1674636 c.435C>G synonymous_variant 0.16
inhA 1674656 p.Ser152Thr missense_variant 0.19
rpsA 1833685 c.144G>C synonymous_variant 0.12
rpsA 1833691 c.150G>A synonymous_variant 0.13
rpsA 1833694 c.153G>C synonymous_variant 0.14
rpsA 1833697 c.156C>G synonymous_variant 0.14
rpsA 1833709 c.168C>T synonymous_variant 0.18
rpsA 1833724 c.183C>T synonymous_variant 0.17
rpsA 1833727 c.186G>C synonymous_variant 0.17
rpsA 1833733 c.192C>G synonymous_variant 0.15
rpsA 1833734 p.Ala65Ser missense_variant 0.16
rpsA 1833748 c.207C>G synonymous_variant 0.18
rpsA 1833770 p.Asn77His missense_variant 0.17
rpsA 1833778 c.237C>G synonymous_variant 0.14
rpsA 1833781 c.240T>G synonymous_variant 0.14
rpsA 1833790 c.249T>C synonymous_variant 0.15
rpsA 1833806 c.265C>T synonymous_variant 0.13
rpsA 1833894 p.Ala118Glu missense_variant 0.13
rpsA 1833928 c.387G>C synonymous_variant 0.14
rpsA 1833949 c.408T>C synonymous_variant 0.12
rpsA 1834423 c.882G>C synonymous_variant 0.12
rpsA 1834451 c.910T>C synonymous_variant 0.12
rpsA 1834465 c.924T>C synonymous_variant 0.15
rpsA 1834468 c.927A>G synonymous_variant 0.14
rpsA 1834489 c.948T>C synonymous_variant 0.12
rpsA 1834573 c.1032G>C synonymous_variant 0.13
rpsA 1834579 c.1038C>G synonymous_variant 0.16
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518609 p.Met165Ile missense_variant 0.13
kasA 2518612 c.498C>G synonymous_variant 0.12
eis 2715188 p.Arg49Cys missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3877710 c.798C>G synonymous_variant 0.13
rpoA 3877737 c.771G>C synonymous_variant 0.14
rpoA 3877743 c.765T>C synonymous_variant 0.14
rpoA 3877770 c.738A>G synonymous_variant 0.13
rpoA 3877788 c.720G>A synonymous_variant 0.12
rpoA 3878106 c.402G>C synonymous_variant 0.14
rpoA 3878118 c.390T>C synonymous_variant 0.14
rpoA 3878127 c.381G>C synonymous_variant 0.14
rpoA 3878130 c.378C>G synonymous_variant 0.14
rpoA 3878143 p.Gly122Asp missense_variant 0.16
rpoA 3878145 c.363C>G synonymous_variant 0.17
rpoA 3878159 p.Thr117Ala missense_variant 0.17
rpoA 3878163 c.345C>G synonymous_variant 0.17
rpoA 3878185 p.Gly108Ala missense_variant 0.17
rpoA 3878193 c.315T>C synonymous_variant 0.16
rpoA 3878202 c.306G>A synonymous_variant 0.17
rpoA 3878205 c.303T>G synonymous_variant 0.17
rpoA 3878217 c.291A>G synonymous_variant 0.19
rpoA 3878247 c.261G>C synonymous_variant 0.18
rpoA 3878253 c.255G>C synonymous_variant 0.18
rpoA 3878256 c.252G>C synonymous_variant 0.18
rpoA 3878264 p.Ser82Gly missense_variant 0.15
rpoA 3878270 p.Leu80Ile missense_variant 0.14
rpoA 3878271 c.237T>C synonymous_variant 0.14
rpoA 3878276 c.232C>T synonymous_variant 0.15
rpoA 3878283 p.Glu75Asp missense_variant 0.16
rpoA 3878292 c.216T>C synonymous_variant 0.12
clpC1 4038878 c.1827A>G synonymous_variant 0.19
clpC1 4038905 c.1800A>G synonymous_variant 0.2
clpC1 4038908 c.1797C>G synonymous_variant 0.19
clpC1 4038914 c.1791G>C synonymous_variant 0.16
clpC1 4038923 c.1782A>G synonymous_variant 0.16
clpC1 4038932 c.1773G>C synonymous_variant 0.16
clpC1 4038953 c.1752A>G synonymous_variant 0.14
clpC1 4038956 c.1749T>C synonymous_variant 0.14
clpC1 4038965 c.1740T>C synonymous_variant 0.13
clpC1 4038971 c.1734T>C synonymous_variant 0.13
clpC1 4038974 c.1731T>G synonymous_variant 0.13
clpC1 4039178 c.1527G>C synonymous_variant 0.12
clpC1 4039823 c.882T>G synonymous_variant 0.13
clpC1 4039831 c.874T>C synonymous_variant 0.13
clpC1 4039832 c.873C>G synonymous_variant 0.12
clpC1 4039850 c.855T>C synonymous_variant 0.18
clpC1 4039865 c.840T>C synonymous_variant 0.18
clpC1 4039889 c.816G>C synonymous_variant 0.18
clpC1 4039898 c.807C>G synonymous_variant 0.13
clpC1 4039901 c.804C>G synonymous_variant 0.13
clpC1 4039931 c.774T>C synonymous_variant 0.12
clpC1 4039937 c.768G>C synonymous_variant 0.12
clpC1 4039970 c.735G>A synonymous_variant 0.13
clpC1 4040057 c.648C>T synonymous_variant 0.12
clpC1 4040498 c.207G>A synonymous_variant 0.13
clpC1 4040522 c.183T>C synonymous_variant 0.12
clpC1 4040531 c.174T>G synonymous_variant 0.13
clpC1 4040534 c.171A>G synonymous_variant 0.15
clpC1 4040540 c.165G>C synonymous_variant 0.15
clpC1 4040551 c.154T>C synonymous_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248220 c.1707A>G synonymous_variant 0.13
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0