TB-Profiler result

Run: ERR4819809
Summary

Run ID: ERR4819809

Sample name:

Date: 01-04-2023 16:19:08

Number of reads: 1884233

Percentage reads mapped: 63.6

Strain: lineage4.6.2.2

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 0.99
lineage4.6.2 Euro-American T;LAM RD726 1.0
lineage4.6.2.2 Euro-American (Cameroon) LAM10-CAM RD726 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
fabG1 1673425 c.-15C>T upstream_gene_variant 1.0 isoniazid, ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6751 c.-551G>C upstream_gene_variant 0.16
gyrA 6811 c.-491C>T upstream_gene_variant 0.13
gyrA 7153 c.-149G>T upstream_gene_variant 0.18
gyrA 7159 c.-143C>T upstream_gene_variant 0.19
gyrA 7162 c.-140C>T upstream_gene_variant 0.18
gyrA 7165 c.-137C>T upstream_gene_variant 0.18
gyrA 7168 c.-134C>G upstream_gene_variant 0.2
gyrA 7178 c.-124T>C upstream_gene_variant 0.2
gyrB 7210 p.Asp657Glu missense_variant 0.15
gyrA 7213 c.-89G>C upstream_gene_variant 0.15
gyrA 7216 c.-86G>A upstream_gene_variant 0.16
gyrA 7225 c.-77T>C upstream_gene_variant 0.15
gyrA 7234 c.-68C>T upstream_gene_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7391 c.90C>T synonymous_variant 0.17
gyrA 7394 c.93T>C synonymous_variant 0.17
gyrA 7397 c.96G>C synonymous_variant 0.17
gyrA 7406 c.105G>C synonymous_variant 0.2
gyrA 7412 c.111C>G synonymous_variant 0.23
gyrA 7433 c.132G>A synonymous_variant 0.21
gyrA 7442 c.141G>C synonymous_variant 0.25
gyrA 7457 c.156T>C synonymous_variant 0.24
gyrA 7463 c.162G>C synonymous_variant 0.25
gyrA 7472 c.171T>C synonymous_variant 0.24
gyrA 7475 c.174A>G synonymous_variant 0.26
gyrA 7480 p.Phe60Tyr missense_variant 0.28
gyrA 7484 c.183T>C synonymous_variant 0.28
gyrA 7499 c.198G>C synonymous_variant 0.3
gyrA 7526 c.225G>C synonymous_variant 0.24
gyrA 7532 c.231T>G synonymous_variant 0.21
gyrA 7541 c.240C>G synonymous_variant 0.2
gyrA 7547 c.246C>T synonymous_variant 0.18
gyrA 7565 c.264C>T synonymous_variant 0.16
gyrA 7569 p.Ala90Ser missense_variant 0.14
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7763 c.462T>G synonymous_variant 0.21
gyrA 7775 c.474C>T synonymous_variant 0.29
gyrA 7784 c.483A>G synonymous_variant 0.38
gyrA 7790 c.489G>C synonymous_variant 0.34
gyrA 7796 c.495G>T synonymous_variant 0.34
gyrA 7799 c.498A>G synonymous_variant 0.31
gyrA 7802 c.501C>G synonymous_variant 0.33
gyrA 7832 c.531G>T synonymous_variant 0.24
gyrA 7835 c.534A>G synonymous_variant 0.24
gyrA 7841 c.540C>T synonymous_variant 0.25
gyrA 7847 c.546G>C synonymous_variant 0.24
gyrA 7859 c.558A>C synonymous_variant 0.26
gyrA 7865 c.564T>C synonymous_variant 0.18
gyrA 8294 c.993T>C synonymous_variant 0.14
gyrA 8315 c.1014G>A synonymous_variant 0.14
gyrA 8324 c.1023T>C synonymous_variant 0.14
gyrA 8327 c.1026C>G synonymous_variant 0.14
gyrA 8339 c.1038A>G synonymous_variant 0.15
gyrA 8340 p.Ala347Ser missense_variant 0.15
gyrA 8852 c.1551T>C synonymous_variant 0.15
gyrA 8858 c.1557T>G synonymous_variant 0.15
gyrA 8870 c.1569G>C synonymous_variant 0.13
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491490 c.708C>T synonymous_variant 0.13
fgd1 491499 c.717G>C synonymous_variant 0.11
fgd1 491523 c.741G>C synonymous_variant 0.15
fgd1 491526 c.744T>C synonymous_variant 0.15
fgd1 491542 c.760T>C synonymous_variant 0.18
fgd1 491547 c.765A>T synonymous_variant 0.19
fgd1 491548 p.Ala256Pro missense_variant 0.19
fgd1 491562 c.780C>T synonymous_variant 0.16
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.16
fgd1 491571 c.789C>T synonymous_variant 0.16
mshA 575785 c.438T>C synonymous_variant 0.14
mshA 575795 p.Ile150Val missense_variant 0.2
mshA 575800 c.453G>C synonymous_variant 0.21
mshA 575803 c.456C>T synonymous_variant 0.2
mshA 575821 c.474G>C synonymous_variant 0.2
mshA 575842 c.495G>C synonymous_variant 0.21
mshA 575864 c.517T>C synonymous_variant 0.16
ccsA 620619 c.729G>C synonymous_variant 0.19
ccsA 620625 c.735A>C synonymous_variant 0.19
ccsA 620631 c.741T>C synonymous_variant 0.24
ccsA 620649 c.759A>G synonymous_variant 0.24
ccsA 620652 c.762C>G synonymous_variant 0.22
ccsA 620661 c.771C>G synonymous_variant 0.19
ccsA 620694 c.804C>G synonymous_variant 0.18
ccsA 620698 p.Val270Ile missense_variant 0.18
rpoB 760178 c.372G>A synonymous_variant 0.14
rpoB 760181 c.375T>C synonymous_variant 0.13
rpoB 760184 c.378A>G synonymous_variant 0.13
rpoB 760196 c.390C>G synonymous_variant 0.17
rpoB 760235 c.429T>C synonymous_variant 0.14
rpoB 760244 c.438G>C synonymous_variant 0.17
rpoB 760283 c.477G>C synonymous_variant 0.16
rpoB 760298 c.492G>C synonymous_variant 0.17
rpoB 760310 c.504G>C synonymous_variant 0.15
rpoB 760316 c.510C>G synonymous_variant 0.16
rpoB 760325 c.519G>C synonymous_variant 0.16
rpoB 760331 c.525G>C synonymous_variant 0.15
rpoB 760334 c.528G>T synonymous_variant 0.16
rpoB 760340 c.534G>T synonymous_variant 0.17
rpoB 760357 p.Thr184Ser missense_variant 0.15
rpoB 760361 c.555T>C synonymous_variant 0.15
rpoB 760376 p.Asp190Glu missense_variant 0.15
rpoB 760406 c.600G>T synonymous_variant 0.16
rpoB 760407 p.Ser201Gly missense_variant 0.16
rpoB 760415 c.609C>T synonymous_variant 0.16
rpoB 760424 c.618C>G synonymous_variant 0.17
rpoB 760430 c.624T>C synonymous_variant 0.19
rpoB 760457 c.651C>T synonymous_variant 0.18
rpoB 760463 c.657C>T synonymous_variant 0.16
rpoB 760475 c.669A>G synonymous_variant 0.18
rpoB 760478 c.672C>T synonymous_variant 0.17
rpoB 760481 c.675G>T synonymous_variant 0.17
rpoB 760484 c.678A>G synonymous_variant 0.17
rpoB 760502 c.696C>G synonymous_variant 0.13
rpoB 760646 c.840C>G synonymous_variant 0.14
rpoB 760655 c.849A>G synonymous_variant 0.17
rpoB 760661 c.855A>C synonymous_variant 0.19
rpoB 760670 c.864G>C synonymous_variant 0.18
rpoB 760674 c.868T>C synonymous_variant 0.16
rpoB 760721 c.915C>G synonymous_variant 0.17
rpoB 760724 c.918T>C synonymous_variant 0.17
rpoB 760730 c.924T>C synonymous_variant 0.16
rpoB 760748 c.942C>G synonymous_variant 0.16
rpoB 760751 c.945G>C synonymous_variant 0.14
rpoB 760755 p.His317Asn missense_variant 0.14
rpoB 760759 p.Val318Ala missense_variant 0.13
rpoB 760769 c.963C>G synonymous_variant 0.14
rpoB 760784 c.978G>T synonymous_variant 0.17
rpoB 760793 c.987A>G synonymous_variant 0.15
rpoB 760841 c.1035T>C synonymous_variant 0.2
rpoB 760859 c.1053T>C synonymous_variant 0.28
rpoB 760862 c.1056G>C synonymous_variant 0.29
rpoB 760877 c.1071G>C synonymous_variant 0.27
rpoB 760883 c.1077G>C synonymous_variant 0.28
rpoB 760886 c.1080A>G synonymous_variant 0.28
rpoB 760887 p.Thr361Val missense_variant 0.28
rpoB 760910 c.1104C>T synonymous_variant 0.28
rpoB 760916 c.1110C>T synonymous_variant 0.22
rpoB 760919 c.1113C>T synonymous_variant 0.22
rpoB 760925 c.1119T>C synonymous_variant 0.22
rpoB 760928 c.1122G>C synonymous_variant 0.17
rpoB 760931 c.1125C>G synonymous_variant 0.15
rpoB 761111 c.1305C>T synonymous_variant 0.17
rpoB 761132 c.1326G>T synonymous_variant 0.19
rpoB 761133 c.1327T>C synonymous_variant 0.19
rpoB 761147 c.1341C>T synonymous_variant 0.2
rpoB 761150 c.1344A>T synonymous_variant 0.2
rpoB 761165 c.1359G>C synonymous_variant 0.19
rpoB 761180 c.1374A>C synonymous_variant 0.17
rpoB 761189 c.1383T>C synonymous_variant 0.19
rpoB 761195 c.1389G>C synonymous_variant 0.14
rpoB 761198 c.1392G>T synonymous_variant 0.14
rpoB 761234 c.1428G>C synonymous_variant 0.21
rpoB 761249 c.1443A>G synonymous_variant 0.23
rpoB 761261 c.1455G>T synonymous_variant 0.25
rpoB 761264 c.1458C>G synonymous_variant 0.26
rpoB 761282 c.1476C>T synonymous_variant 0.27
rpoB 761288 c.1482G>T synonymous_variant 0.27
rpoB 761318 c.1512G>T synonymous_variant 0.25
rpoB 761327 c.1521A>G synonymous_variant 0.21
rpoB 761330 c.1524G>C synonymous_variant 0.2
rpoB 761345 c.1539G>C synonymous_variant 0.2
rpoB 761354 c.1548C>T synonymous_variant 0.2
rpoB 761360 c.1554T>C synonymous_variant 0.16
rpoB 761362 p.Ser519Thr missense_variant 0.15
rpoB 761367 p.Glu521Gln missense_variant 0.16
rpoB 761374 p.Val523Asp missense_variant 0.14
rpoB 761408 c.1602G>C synonymous_variant 0.12
rpoB 761414 c.1608A>G synonymous_variant 1.0
rpoB 761537 c.1731C>G synonymous_variant 0.18
rpoB 761552 c.1746G>C synonymous_variant 0.19
rpoB 761555 c.1749G>C synonymous_variant 0.18
rpoB 761558 c.1752C>G synonymous_variant 0.19
rpoB 761570 c.1764T>C synonymous_variant 0.2
rpoB 761573 c.1767C>G synonymous_variant 0.2
rpoB 761579 c.1773G>C synonymous_variant 0.21
rpoB 761600 c.1794T>C synonymous_variant 0.28
rpoB 761606 c.1800C>G synonymous_variant 0.28
rpoB 761612 c.1806G>T synonymous_variant 0.27
rpoB 761615 c.1809A>C synonymous_variant 0.27
rpoB 761636 c.1830G>T synonymous_variant 0.2
rpoB 761645 c.1839C>G synonymous_variant 0.19
rpoB 761648 c.1842T>C synonymous_variant 0.18
rpoB 761666 c.1860G>C synonymous_variant 0.13
rpoB 761669 c.1863C>T synonymous_variant 0.13
rpoB 761675 c.1869G>T synonymous_variant 0.16
rpoB 761930 c.2124G>C synonymous_variant 0.13
rpoB 761948 c.2142G>C synonymous_variant 0.25
rpoB 761954 c.2148C>G synonymous_variant 0.27
rpoB 762008 c.2202C>T synonymous_variant 0.35
rpoB 762014 c.2208C>T synonymous_variant 0.38
rpoB 762047 c.2241G>A synonymous_variant 0.33
rpoB 762053 c.2247T>C synonymous_variant 0.33
rpoB 762062 c.2256T>C synonymous_variant 0.28
rpoB 762065 c.2259T>C synonymous_variant 0.27
rpoB 762083 c.2277T>C synonymous_variant 0.21
rpoB 762086 c.2280G>C synonymous_variant 0.19
rpoB 762101 c.2295C>G synonymous_variant 0.26
rpoB 762114 p.Ile770Val missense_variant 0.23
rpoB 762131 c.2325C>G synonymous_variant 0.17
rpoB 762137 c.2331C>T synonymous_variant 0.2
rpoB 762140 c.2334G>C synonymous_variant 0.2
rpoB 762143 c.2337T>C synonymous_variant 0.19
rpoB 762149 c.2343G>C synonymous_variant 0.22
rpoB 762158 c.2352G>C synonymous_variant 0.22
rpoB 762167 c.2361T>C synonymous_variant 0.26
rpoB 762176 c.2370T>C synonymous_variant 0.24
rpoB 762185 c.2379G>C synonymous_variant 0.26
rpoB 762233 c.2427G>C synonymous_variant 0.3
rpoB 762245 c.2439G>C synonymous_variant 0.33
rpoB 762284 c.2478G>T synonymous_variant 0.28
rpoB 762293 c.2487T>C synonymous_variant 0.27
rpoB 762308 c.2502G>C synonymous_variant 0.18
rpoB 762317 c.2511A>G synonymous_variant 0.14
rpoB 762329 c.2523G>C synonymous_variant 0.16
rpoB 762369 c.2563T>C synonymous_variant 0.14
rpoC 762374 c.-996G>C upstream_gene_variant 0.16
rpoC 762395 c.-975G>C upstream_gene_variant 0.13
rpoC 762398 c.-972T>C upstream_gene_variant 0.13
rpoC 762404 c.-966T>C upstream_gene_variant 0.13
rpoC 762410 c.-960T>C upstream_gene_variant 0.15
rpoC 762416 c.-954A>G upstream_gene_variant 0.17
rpoC 762482 c.-888C>T upstream_gene_variant 0.12
rpoC 762491 c.-879T>C upstream_gene_variant 0.12
rpoB 762881 p.Met1025Ile missense_variant 0.13
rpoC 762920 c.-450C>T upstream_gene_variant 0.22
rpoC 762929 c.-441G>C upstream_gene_variant 0.17
rpoC 762962 c.-408C>T upstream_gene_variant 0.2
rpoC 763007 c.-363C>T upstream_gene_variant 0.12
rpoC 763028 c.-342T>C upstream_gene_variant 0.24
rpoC 763031 c.-339T>G upstream_gene_variant 0.23
rpoC 763053 c.-317T>C upstream_gene_variant 0.18
rpoC 763070 c.-300T>C upstream_gene_variant 0.16
rpoC 763085 c.-285C>G upstream_gene_variant 0.16
rpoC 763103 c.-267G>C upstream_gene_variant 0.27
rpoC 763115 c.-255T>C upstream_gene_variant 0.21
rpoC 763127 c.-243G>C upstream_gene_variant 0.19
rpoC 763130 c.-240G>A upstream_gene_variant 0.18
rpoC 763133 c.-237G>C upstream_gene_variant 0.19
rpoC 763136 c.-234C>T upstream_gene_variant 0.21
rpoC 763142 c.-228C>G upstream_gene_variant 0.21
rpoC 763160 c.-210G>T upstream_gene_variant 0.21
rpoC 763166 c.-204A>G upstream_gene_variant 0.22
rpoC 763169 c.-201A>G upstream_gene_variant 0.22
rpoC 763190 c.-180C>T upstream_gene_variant 0.17
rpoC 763456 c.87A>G synonymous_variant 0.17
rpoC 763468 c.99G>C synonymous_variant 0.24
rpoC 763486 c.117T>C synonymous_variant 0.3
rpoC 763492 c.123G>T synonymous_variant 0.34
rpoC 763528 c.159G>A synonymous_variant 0.4
rpoC 763546 c.177A>G synonymous_variant 0.4
rpoC 763558 c.189C>T synonymous_variant 0.44
rpoC 763570 c.201G>C synonymous_variant 0.32
rpoC 763573 c.204G>C synonymous_variant 0.35
rpoC 763594 c.225C>T synonymous_variant 0.42
rpoC 763603 c.234C>T synonymous_variant 0.33
rpoC 763615 c.246G>C synonymous_variant 0.38
rpoC 763618 c.249C>T synonymous_variant 0.37
rpoC 763633 c.264T>C synonymous_variant 0.37
rpoC 763660 c.291T>G synonymous_variant 0.4
rpoC 763666 c.297G>A synonymous_variant 0.45
rpoC 763675 c.306C>G synonymous_variant 0.41
rpoC 763702 c.333C>G synonymous_variant 0.41
rpoC 763709 c.340C>T synonymous_variant 0.42
rpoC 763714 c.345G>C synonymous_variant 0.38
rpoC 763717 c.348T>C synonymous_variant 0.41
rpoC 763723 c.354G>C synonymous_variant 0.39
rpoC 763732 c.363C>T synonymous_variant 0.46
rpoC 763741 c.372C>T synonymous_variant 0.42
rpoC 763747 c.378G>A synonymous_variant 0.41
rpoC 763765 c.396T>G synonymous_variant 0.39
rpoC 763792 p.Glu141Asp missense_variant 0.29
rpoC 763807 c.438T>C synonymous_variant 0.26
rpoC 763813 c.444C>G synonymous_variant 0.25
rpoC 763831 c.462A>G synonymous_variant 0.26
rpoC 763837 c.468G>C synonymous_variant 0.24
rpoC 763840 c.471G>C synonymous_variant 0.24
rpoC 763858 c.489A>G synonymous_variant 0.18
rpoC 763861 c.492C>T synonymous_variant 0.19
rpoC 763872 p.Gly168Ala missense_variant 0.2
rpoC 763876 p.Glu169Asp missense_variant 0.18
rpoC 763879 c.510A>G synonymous_variant 0.18
rpoC 763882 c.513G>A synonymous_variant 0.18
rpoC 763891 c.522G>C synonymous_variant 0.23
rpoC 763894 c.525A>G synonymous_variant 0.21
rpoC 763900 c.531G>C synonymous_variant 0.22
rpoC 763921 c.552G>C synonymous_variant 0.17
rpoC 763924 c.555G>A synonymous_variant 0.17
rpoC 763930 c.561G>A synonymous_variant 0.16
rpoC 763933 c.564C>T synonymous_variant 0.15
rpoC 763940 p.Ala191Ser missense_variant 0.15
rpoC 763945 c.576T>C synonymous_variant 0.13
rpoC 763951 c.582G>C synonymous_variant 0.15
rpoC 763960 c.591T>G synonymous_variant 0.14
rpoC 763969 c.600C>T synonymous_variant 0.15
rpoC 763987 c.618C>T synonymous_variant 0.16
rpoC 764040 p.Ser224Thr missense_variant 0.14
rpoC 764044 c.675T>C synonymous_variant 0.23
rpoC 764059 c.690G>T synonymous_variant 0.19
rpoC 764071 c.702G>C synonymous_variant 0.15
rpoC 764084 p.Asn239Val missense_variant 0.14
rpoC 764089 c.720C>G synonymous_variant 0.15
rpoC 764098 c.729A>G synonymous_variant 0.16
rpoC 764101 c.732C>G synonymous_variant 0.17
rpoC 764102 p.Val245Gln missense_variant 0.17
rpoC 764153 p.Gln262Lys missense_variant 0.16
rpoC 764161 c.792G>C synonymous_variant 0.21
rpoC 764182 p.Asp271Glu missense_variant 0.25
rpoC 764188 c.819A>G synonymous_variant 0.24
rpoC 764195 c.826_828delTCGinsAGC synonymous_variant 0.22
rpoC 764203 c.834G>C synonymous_variant 0.22
rpoC 764206 p.Asp279Glu missense_variant 0.22
rpoC 764207 p.Val280Thr missense_variant 0.21
rpoC 764215 c.846A>C synonymous_variant 0.2
rpoC 764217 p.Asn283Ser missense_variant 0.19
rpoC 764239 c.870T>G synonymous_variant 0.3
rpoC 764254 c.885G>C synonymous_variant 0.25
rpoC 764257 c.888G>C synonymous_variant 0.21
rpoC 764263 c.894G>C synonymous_variant 0.18
rpoC 764266 c.897T>C synonymous_variant 0.18
rpoC 764272 c.903G>C synonymous_variant 0.2
rpoC 764278 c.909A>G synonymous_variant 0.21
rpoC 764293 c.924G>C synonymous_variant 0.26
rpoC 764297 p.Met310Leu missense_variant 0.26
rpoC 764344 c.975C>T synonymous_variant 0.26
rpoC 764353 c.984G>T synonymous_variant 0.21
rpoC 764365 c.996C>T synonymous_variant 0.22
rpoC 764371 c.1002G>C synonymous_variant 0.19
rpoC 764380 c.1011G>C synonymous_variant 0.21
rpoC 764387 c.1018T>C synonymous_variant 0.23
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.24
rpoC 764431 c.1062G>C synonymous_variant 0.17
rpoC 764434 c.1065A>G synonymous_variant 0.17
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.17
rpoC 764446 c.1077T>C synonymous_variant 0.21
rpoC 764449 c.1080G>C synonymous_variant 0.24
rpoC 764458 c.1089G>C synonymous_variant 0.26
rpoC 764461 c.1092A>G synonymous_variant 0.27
rpoC 764485 c.1116G>C synonymous_variant 0.27
rpoC 764491 c.1122G>T synonymous_variant 0.28
rpoC 764497 c.1128A>G synonymous_variant 0.26
rpoC 764500 c.1131C>G synonymous_variant 0.28
rpoC 764503 c.1134G>C synonymous_variant 0.28
rpoC 764521 c.1152T>C synonymous_variant 0.31
rpoC 764527 c.1158C>T synonymous_variant 0.36
rpoC 764536 c.1167G>T synonymous_variant 0.33
rpoC 764539 c.1170C>G synonymous_variant 0.34
rpoC 764575 c.1206T>G synonymous_variant 0.32
rpoC 764605 c.1236G>C synonymous_variant 0.31
rpoC 764611 c.1242G>T synonymous_variant 0.33
rpoC 764623 c.1254C>G synonymous_variant 0.36
rpoC 764626 c.1257C>T synonymous_variant 0.33
rpoC 764632 c.1263T>C synonymous_variant 0.4
rpoC 764650 c.1281G>T synonymous_variant 0.4
rpoC 764701 c.1332C>G synonymous_variant 0.35
rpoC 764713 c.1344G>T synonymous_variant 0.36
rpoC 764716 c.1347G>C synonymous_variant 0.36
rpoC 764746 c.1377G>T synonymous_variant 0.33
rpoC 764752 c.1383G>C synonymous_variant 0.34
rpoC 764758 c.1389C>G synonymous_variant 0.33
rpoC 764764 c.1395T>C synonymous_variant 0.31
rpoC 764803 c.1434C>T synonymous_variant 0.25
rpoC 764809 c.1440C>T synonymous_variant 0.24
rpoC 764815 c.1446A>G synonymous_variant 0.22
rpoC 764824 c.1455T>C synonymous_variant 0.2
rpoC 764827 c.1458G>C synonymous_variant 0.16
rpoC 764858 c.1489T>C synonymous_variant 0.23
rpoC 764869 c.1500C>T synonymous_variant 0.23
rpoC 764875 c.1506C>T synonymous_variant 0.21
rpoC 764878 c.1509C>G synonymous_variant 0.22
rpoC 764887 c.1518G>C synonymous_variant 0.23
rpoC 764888 c.1519T>C synonymous_variant 0.22
rpoC 764911 c.1542A>G synonymous_variant 0.29
rpoC 764912 p.Met515Gln missense_variant 0.28
rpoC 764935 c.1566T>C synonymous_variant 0.32
rpoC 764948 c.1579T>C synonymous_variant 0.28
rpoC 764968 c.1599T>C synonymous_variant 0.23
rpoC 765383 p.Met672Leu missense_variant 0.21
rpoC 765403 c.2034G>C synonymous_variant 0.21
rpoC 765404 p.Leu679Lys missense_variant 0.22
rpoC 765409 c.2040T>C synonymous_variant 0.2
rpoC 765412 c.2043T>C synonymous_variant 0.2
rpoC 765425 p.Lys686Glu missense_variant 0.23
rpoC 765445 c.2076G>C synonymous_variant 0.21
rpoC 765452 p.Ala695Arg missense_variant 0.25
rpoC 765466 c.2097C>T synonymous_variant 0.22
rpoC 765496 c.2127C>G synonymous_variant 0.23
rpoC 765499 c.2130C>G synonymous_variant 0.22
rpoC 765529 c.2160C>T synonymous_variant 0.19
rpoC 765533 p.Tyr722His missense_variant 0.15
rpoC 765871 c.2502T>C synonymous_variant 0.15
rpoC 765875 p.Val836Ile missense_variant 0.16
rpoC 765886 c.2517C>G synonymous_variant 0.15
rpoC 765908 c.2539C>T synonymous_variant 0.15
rpoC 765934 c.2565C>T synonymous_variant 0.2
rpoC 765940 c.2571A>T synonymous_variant 0.17
rpoC 765946 c.2577C>T synonymous_variant 0.13
rpoC 765994 c.2625A>T synonymous_variant 0.14
rpoC 766309 c.2940G>C synonymous_variant 0.13
rpoC 766363 c.2994G>C synonymous_variant 0.12
rpoC 766714 c.3345G>C synonymous_variant 0.17
rpoC 766717 c.3348C>G synonymous_variant 0.17
rpoC 766720 c.3351C>T synonymous_variant 0.17
rpoC 766726 c.3357T>C synonymous_variant 0.22
rpoC 766738 c.3369G>T synonymous_variant 0.19
rpoC 766741 c.3372G>C synonymous_variant 0.19
rpoC 766747 c.3378C>T synonymous_variant 0.24
rpoC 766765 c.3396A>C synonymous_variant 0.22
rpoC 766771 c.3402G>C synonymous_variant 0.22
rpoC 766774 c.3405T>C synonymous_variant 0.22
rpoC 766775 p.Arg1136Lys missense_variant 0.22
rpoC 766798 c.3429C>G synonymous_variant 0.17
rpoC 767008 c.3639G>A synonymous_variant 0.14
rpoC 767020 c.3651C>G synonymous_variant 0.19
rpoC 767023 c.3654C>T synonymous_variant 0.23
rpoC 767098 c.3729T>C synonymous_variant 0.26
rpoC 767104 c.3735C>G synonymous_variant 0.24
rpoC 767105 p.Asn1246Gln missense_variant 0.25
rpoC 767119 c.3750A>G synonymous_variant 0.23
rpoC 767134 c.3765C>T synonymous_variant 0.18
rpoC 767138 c.3769C>T synonymous_variant 0.19
rpoC 767158 c.3789T>C synonymous_variant 0.18
rpoC 767162 p.Asn1265Ala missense_variant 0.15
rpoC 767174 p.Asn1269Asp missense_variant 0.15
rpoC 767180 p.Ala1271Gln missense_variant 0.15
rpoC 767191 c.3822C>G synonymous_variant 0.15
rpoC 767197 c.3828G>A synonymous_variant 0.16
rpoC 767200 c.3831G>A synonymous_variant 0.15
rpoC 767221 c.3852C>G synonymous_variant 0.15
rpoC 767230 c.3861G>C synonymous_variant 0.16
rpoC 767233 c.3864T>C synonymous_variant 0.16
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775886 c.2595A>T synonymous_variant 0.14
mmpL5 775904 c.2577G>A synonymous_variant 0.16
mmpL5 775915 p.Ala856Ser missense_variant 0.15
mmpL5 775916 c.2565T>C synonymous_variant 0.16
mmpL5 775951 c.2530C>T synonymous_variant 0.23
mmpL5 775966 p.Ala839Ser missense_variant 0.25
mmpL5 775981 p.Leu834Met missense_variant 0.17
mmpR5 778298 c.-692C>T upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781595 c.36T>C synonymous_variant 0.14
rpsL 781598 c.39G>C synonymous_variant 0.14
rpsL 781605 p.Ile16Val missense_variant 0.14
rpsL 781608 p.Ser17Ala missense_variant 0.14
rpsL 781628 c.69T>C synonymous_variant 0.19
rpsL 781631 c.72G>C synonymous_variant 0.2
rpsL 781649 c.90T>C synonymous_variant 0.18
rpsL 781655 c.96T>C synonymous_variant 0.18
rpsL 781658 c.99A>G synonymous_variant 0.17
rpsL 781829 c.270G>C synonymous_variant 0.14
rpsL 781832 c.273T>C synonymous_variant 0.14
rpsL 781838 c.279G>C synonymous_variant 0.2
rpsL 781841 c.282C>T synonymous_variant 0.18
rpsL 781859 c.300T>G synonymous_variant 0.24
rpsL 781865 c.306G>C synonymous_variant 0.23
rpsL 781868 c.309T>C synonymous_variant 0.23
rpsL 781871 c.312G>C synonymous_variant 0.24
rpsL 781892 c.333A>G synonymous_variant 0.27
rpsL 781898 c.339A>C synonymous_variant 0.28
rpsL 781901 c.342C>T synonymous_variant 0.29
rpsL 781907 c.348T>C synonymous_variant 0.29
rpsL 781916 c.357T>C synonymous_variant 0.28
rpsL 781929 p.Gly124Ser missense_variant 0.26
rplC 800654 c.-155T>C upstream_gene_variant 0.17
rplC 800678 c.-131C>T upstream_gene_variant 0.27
rplC 800684 c.-125G>A upstream_gene_variant 0.27
rplC 800693 c.-116A>C upstream_gene_variant 0.27
rplC 800702 c.-107G>A upstream_gene_variant 0.29
rplC 800703 c.-106T>C upstream_gene_variant 0.27
rplC 800715 c.-94A>C upstream_gene_variant 0.25
rplC 800720 c.-89T>C upstream_gene_variant 0.26
rplC 800723 c.-86C>G upstream_gene_variant 0.27
rplC 800735 c.-74C>G upstream_gene_variant 0.25
rplC 800762 c.-47T>G upstream_gene_variant 0.12
rplC 800964 c.156G>C synonymous_variant 0.16
rplC 800985 c.177A>G synonymous_variant 0.16
rplC 801195 c.387G>T synonymous_variant 0.15
rplC 801205 p.Arg133Ala missense_variant 0.15
rplC 801210 c.402T>C synonymous_variant 0.14
rplC 801220 p.Ser138Ala missense_variant 0.15
rplC 801231 c.423C>T synonymous_variant 0.14
rplC 801237 c.429G>A synonymous_variant 0.15
fbiC 1303509 c.579G>C synonymous_variant 0.16
fbiC 1303512 c.582T>G synonymous_variant 0.17
fbiC 1303531 p.Met201Leu missense_variant 0.17
fbiC 1303536 c.606G>A synonymous_variant 0.19
fbiC 1303539 c.609G>C synonymous_variant 0.19
fbiC 1303545 c.615A>G synonymous_variant 0.19
fbiC 1303548 c.618G>C synonymous_variant 0.19
fbiC 1303551 c.621G>C synonymous_variant 0.2
fbiC 1303554 c.624G>A synonymous_variant 0.19
fbiC 1303581 c.651G>C synonymous_variant 0.17
fbiC 1303584 c.654C>G synonymous_variant 0.15
fbiC 1303587 c.657G>C synonymous_variant 0.15
fbiC 1304640 c.1710A>C synonymous_variant 0.14
fbiC 1304694 c.1764A>G synonymous_variant 0.16
fbiC 1304715 c.1785G>T synonymous_variant 0.16
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.21
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.22
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.28
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.27
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.25
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.15
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.15
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.13
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.14
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.17
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.17
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.15
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.17
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.2
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.2
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.29
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.43
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.33
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.33
rrs 1472487 n.643dupT non_coding_transcript_exon_variant 1.0
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.8
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.43
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.33
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.33
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.62
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.5
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.5
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.5
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.2
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.18
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.18
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.13
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.18
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.29
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.4
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.4
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.43
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.5
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.43
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.43
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.38
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.23
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.18
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.18
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.25
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.18
inhA 1674331 p.Leu44Met missense_variant 0.2
inhA 1674334 p.Arg45Lys missense_variant 0.21
inhA 1674342 c.141T>C synonymous_variant 0.19
inhA 1674352 p.Thr51Ala missense_variant 0.17
inhA 1674361 c.160C>T synonymous_variant 0.17
inhA 1674365 c.165_166delGG frameshift_variant 0.17
inhA 1674375 c.174C>G synonymous_variant 0.17
inhA 1674384 c.183C>G synonymous_variant 0.17
inhA 1674399 c.198A>G synonymous_variant 0.19
inhA 1674690 c.489C>G synonymous_variant 0.17
inhA 1674702 c.501G>T synonymous_variant 0.18
inhA 1674703 c.502_504delTTGinsCTC synonymous_variant 0.18
inhA 1674718 c.517A>C synonymous_variant 0.26
inhA 1674729 c.528G>T synonymous_variant 0.26
inhA 1674742 p.Lys181Ala missense_variant 0.24
inhA 1674745 p.Tyr182Ala missense_variant 0.24
inhA 1674753 c.552G>C synonymous_variant 0.25
inhA 1674774 c.573A>C synonymous_variant 0.26
inhA 1674777 c.576C>G synonymous_variant 0.24
inhA 1674780 c.579T>G synonymous_variant 0.25
inhA 1674789 c.588G>T synonymous_variant 0.23
inhA 1674792 c.591G>C synonymous_variant 0.2
inhA 1674795 c.594G>C synonymous_variant 0.19
inhA 1674801 c.600T>C synonymous_variant 0.15
inhA 1674804 c.603G>C synonymous_variant 0.15
rpsA 1833554 p.Thr5Ser missense_variant 0.13
rpsA 1833589 c.48A>C synonymous_variant 0.13
rpsA 1833595 c.54T>G synonymous_variant 0.13
rpsA 1833596 p.Ser19Ala missense_variant 0.13
rpsA 1833616 c.75A>C synonymous_variant 0.14
rpsA 1833628 c.87G>C synonymous_variant 0.15
rpsA 1833634 c.93G>A synonymous_variant 0.17
rpsA 1833679 c.138G>T synonymous_variant 0.13
rpsA 1833709 c.168C>T synonymous_variant 0.13
rpsA 1833724 c.183C>T synonymous_variant 0.16
rpsA 1833727 c.186G>C synonymous_variant 0.13
rpsA 1833760 c.219C>T synonymous_variant 0.15
rpsA 1833787 c.246C>G synonymous_variant 0.18
rpsA 1833790 c.249T>C synonymous_variant 0.17
rpsA 1833793 c.252C>T synonymous_variant 0.19
rpsA 1833802 c.261A>G synonymous_variant 0.23
rpsA 1833808 c.267G>C synonymous_variant 0.2
rpsA 1833811 c.270G>T synonymous_variant 0.22
rpsA 1833829 c.288A>G synonymous_variant 0.32
rpsA 1833832 c.291G>A synonymous_variant 0.31
rpsA 1833838 c.297G>C synonymous_variant 0.35
rpsA 1833841 c.300C>G synonymous_variant 0.33
rpsA 1833847 c.306C>G synonymous_variant 0.34
rpsA 1833856 c.315A>G synonymous_variant 0.31
rpsA 1833862 c.321G>T synonymous_variant 0.27
rpsA 1833894 p.Ala118Glu missense_variant 0.24
rpsA 1833904 c.363G>A synonymous_variant 0.23
rpsA 1833928 c.387G>C synonymous_variant 0.29
rpsA 1833949 c.408T>C synonymous_variant 0.31
rpsA 1833970 c.429G>T synonymous_variant 0.29
rpsA 1833976 c.435C>T synonymous_variant 0.29
rpsA 1833979 c.438T>C synonymous_variant 0.31
rpsA 1833991 c.450C>A synonymous_variant 0.3
rpsA 1834000 c.459G>C synonymous_variant 0.24
rpsA 1834009 c.468C>T synonymous_variant 0.22
rpsA 1834012 c.471G>T synonymous_variant 0.22
rpsA 1834015 c.474G>C synonymous_variant 0.22
rpsA 1834021 c.480C>T synonymous_variant 0.21
rpsA 1834030 c.489C>G synonymous_variant 0.21
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.2
rpsA 1834102 c.561T>C synonymous_variant 0.22
rpsA 1834279 c.738C>T synonymous_variant 0.16
rpsA 1834297 c.756C>T synonymous_variant 0.21
rpsA 1834303 c.762T>G synonymous_variant 0.23
rpsA 1834306 c.765T>C synonymous_variant 0.25
rpsA 1834345 c.804C>T synonymous_variant 0.28
rpsA 1834348 c.807T>C synonymous_variant 0.28
rpsA 1834361 c.820T>C synonymous_variant 0.25
rpsA 1834366 c.825A>G synonymous_variant 0.26
rpsA 1834396 c.855G>C synonymous_variant 0.21
rpsA 1834411 c.870T>C synonymous_variant 0.18
rpsA 1834423 c.882G>T synonymous_variant 0.2
rpsA 1834451 c.910T>C synonymous_variant 0.21
rpsA 1834456 c.915T>G synonymous_variant 0.23
rpsA 1834468 c.927A>G synonymous_variant 0.21
rpsA 1834489 c.948T>C synonymous_variant 0.19
rpsA 1834498 c.957C>T synonymous_variant 0.19
rpsA 1834513 c.972C>G synonymous_variant 0.21
rpsA 1834520 p.Ala327Ser missense_variant 0.2
rpsA 1834528 c.987T>C synonymous_variant 0.2
rpsA 1834540 c.999G>C synonymous_variant 0.18
rpsA 1834543 c.1002C>G synonymous_variant 0.16
rpsA 1834546 c.1005T>C synonymous_variant 0.16
rpsA 1834606 c.1065C>T synonymous_variant 0.17
rpsA 1834609 c.1068T>C synonymous_variant 0.12
rpsA 1834666 c.1125G>C synonymous_variant 0.16
rpsA 1834667 p.Ala376Ser missense_variant 0.16
rpsA 1834690 c.1149T>C synonymous_variant 0.18
rpsA 1834732 c.1191T>C synonymous_variant 0.18
rpsA 1834738 c.1197A>G synonymous_variant 0.19
rpsA 1834753 c.1212T>C synonymous_variant 0.21
rpsA 1834756 c.1215G>A synonymous_variant 0.21
rpsA 1834759 c.1218A>C synonymous_variant 0.24
rpsA 1834765 p.Glu408Asp missense_variant 0.23
rpsA 1834774 c.1233C>G synonymous_variant 0.17
rpsA 1834776 p.Ala412Glu missense_variant 0.17
rpsA 1834780 c.1239A>G synonymous_variant 0.16
rpsA 1834786 c.1245A>G synonymous_variant 0.16
rpsA 1834789 c.1248T>C synonymous_variant 0.17
rpsA 1834792 c.1251G>C synonymous_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155389 c.723C>G synonymous_variant 1.0
katG 2155696 p.Ala139Val missense_variant 0.17
katG 2155716 c.396T>G synonymous_variant 0.18
katG 2155722 c.390G>C synonymous_variant 0.18
katG 2155728 c.384G>C synonymous_variant 0.18
katG 2155742 p.Gly124Arg missense_variant 0.17
Rv1979c 2221746 c.1416_1418dupCCG disruptive_inframe_insertion 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2517941 c.-174C>G upstream_gene_variant 0.3
kasA 2517959 c.-156C>T upstream_gene_variant 0.29
kasA 2517962 c.-153C>G upstream_gene_variant 0.26
kasA 2517968 c.-147T>C upstream_gene_variant 0.28
kasA 2517974 c.-141T>C upstream_gene_variant 0.27
kasA 2517980 c.-135C>T upstream_gene_variant 0.18
kasA 2517989 c.-126T>G upstream_gene_variant 0.16
kasA 2517993 c.-122G>T upstream_gene_variant 0.22
kasA 2518756 c.642G>C synonymous_variant 0.18
kasA 2518780 p.Glu222Asp missense_variant 0.15
kasA 2518783 c.669T>C synonymous_variant 0.15
kasA 2518785 p.Glu224Ala missense_variant 0.14
kasA 2518787 p.Arg225Gly missense_variant 0.13
kasA 2518792 c.678C>G synonymous_variant 0.13
kasA 2518795 c.681C>T synonymous_variant 0.13
kasA 2518813 c.699C>T synonymous_variant 0.13
kasA 2518816 c.702C>T synonymous_variant 0.14
kasA 2518825 c.711T>C synonymous_variant 0.14
thyX 3067403 c.543C>G synonymous_variant 0.14
thyX 3067415 c.531C>T synonymous_variant 0.12
thyX 3067474 p.Pro158Ala missense_variant 0.97
Rv3083 3448567 p.His22Asp missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612571 c.546C>T synonymous_variant 1.0
Rv3236c 3612910 p.Leu69Phe missense_variant 1.0
rpoA 3877545 c.963G>C synonymous_variant 0.13
rpoA 3877557 c.951C>G synonymous_variant 0.13
rpoA 3877560 c.948C>T synonymous_variant 0.14
rpoA 3877566 p.Ser314Thr missense_variant 0.14
rpoA 3877569 p.Pro313Ala missense_variant 0.15
rpoA 3877587 c.921A>G synonymous_variant 0.16
rpoA 3877590 c.918G>C synonymous_variant 0.17
rpoA 3877593 c.915C>T synonymous_variant 0.15
rpoA 3877638 c.870T>C synonymous_variant 0.16
rpoA 3877647 c.861C>T synonymous_variant 0.18
rpoA 3877656 c.852T>G synonymous_variant 0.17
rpoA 3877668 c.840A>G synonymous_variant 0.17
rpoA 3877671 c.837C>G synonymous_variant 0.23
rpoA 3877677 c.831G>C synonymous_variant 0.18
rpoA 3877680 c.828G>C synonymous_variant 0.17
rpoA 3877683 c.825G>C synonymous_variant 0.17
rpoA 3877686 c.822A>G synonymous_variant 0.17
rpoA 3877695 c.813C>G synonymous_variant 0.17
rpoA 3877704 c.804G>T synonymous_variant 0.16
rpoA 3877818 c.690A>G synonymous_variant 0.21
rpoA 3877848 c.660C>T synonymous_variant 0.28
rpoA 3877856 c.652T>C synonymous_variant 0.27
rpoA 3877857 c.651G>A synonymous_variant 0.27
rpoA 3877866 c.642G>C synonymous_variant 0.31
rpoA 3877875 c.633T>A synonymous_variant 0.28
rpoA 3877878 c.630G>C synonymous_variant 0.26
rpoA 3877887 c.621G>C synonymous_variant 0.24
rpoA 3877893 c.615C>T synonymous_variant 0.27
rpoA 3877905 c.603A>G synonymous_variant 0.27
rpoA 3877908 c.600T>C synonymous_variant 0.25
rpoA 3877920 c.588G>C synonymous_variant 0.17
rpoA 3877923 c.585C>T synonymous_variant 0.16
rpoA 3877926 c.582G>C synonymous_variant 0.16
rpoA 3877962 c.546G>T synonymous_variant 0.13
rpoA 3878103 c.405A>G synonymous_variant 0.15
rpoA 3878118 c.390T>C synonymous_variant 0.15
rpoA 3878127 c.381G>C synonymous_variant 0.14
rpoA 3878143 p.Gly122Asp missense_variant 0.24
rpoA 3878145 c.363C>G synonymous_variant 0.25
rpoA 3878160 c.348C>G synonymous_variant 0.28
rpoA 3878163 c.345C>T synonymous_variant 0.28
rpoA 3878187 c.321C>A synonymous_variant 0.27
rpoA 3878193 c.315T>C synonymous_variant 0.28
rpoA 3878197 p.Glu104Ala missense_variant 0.28
rpoA 3878205 c.303T>C synonymous_variant 0.31
rpoA 3878217 c.291A>G synonymous_variant 0.34
rpoA 3878238 c.270C>T synonymous_variant 0.28
rpoA 3878244 c.264G>A synonymous_variant 0.22
rpoA 3878247 c.261G>A synonymous_variant 0.2
rpoA 3878256 c.252G>C synonymous_variant 0.2
rpoA 3878264 p.Ser82Gly missense_variant 0.2
rpoA 3878271 c.237T>C synonymous_variant 0.16
rpoA 3878283 p.Glu75Asp missense_variant 0.14
clpC1 4038519 p.Arg729Gln missense_variant 0.16
clpC1 4038530 p.Glu725Asp missense_variant 0.18
clpC1 4038533 p.Arg724Gln missense_variant 0.18
clpC1 4038536 c.2169C>G synonymous_variant 0.18
clpC1 4038551 c.2154C>G synonymous_variant 0.24
clpC1 4038563 c.2142C>T synonymous_variant 0.22
clpC1 4038584 c.2121G>A synonymous_variant 0.25
clpC1 4038587 c.2118C>G synonymous_variant 0.25
clpC1 4038596 c.2109A>G synonymous_variant 0.2
clpC1 4038602 c.2103G>C synonymous_variant 0.21
clpC1 4038725 c.1980C>G synonymous_variant 0.14
clpC1 4038740 c.1965G>C synonymous_variant 0.17
clpC1 4038755 c.1950G>C synonymous_variant 0.21
clpC1 4038767 c.1938G>T synonymous_variant 0.18
clpC1 4038770 c.1935C>T synonymous_variant 0.18
clpC1 4038773 c.1932T>C synonymous_variant 0.17
clpC1 4038776 c.1929G>A synonymous_variant 0.17
clpC1 4038779 c.1926C>G synonymous_variant 0.21
clpC1 4038782 c.1923G>C synonymous_variant 0.2
clpC1 4038790 c.1915C>T synonymous_variant 0.22
clpC1 4038812 c.1893T>C synonymous_variant 0.21
clpC1 4038815 c.1890G>C synonymous_variant 0.2
clpC1 4038818 c.1887G>A synonymous_variant 0.2
clpC1 4038842 c.1863G>C synonymous_variant 0.19
clpC1 4038860 c.1845G>C synonymous_variant 0.23
clpC1 4038878 c.1827A>G synonymous_variant 0.2
clpC1 4038890 c.1815G>A synonymous_variant 0.22
clpC1 4038905 c.1800A>G synonymous_variant 0.22
clpC1 4038908 c.1797C>G synonymous_variant 0.22
clpC1 4038911 c.1794G>T synonymous_variant 0.2
clpC1 4038914 c.1791G>C synonymous_variant 0.24
clpC1 4038917 c.1788C>T synonymous_variant 0.24
clpC1 4038923 c.1782A>G synonymous_variant 0.23
clpC1 4038941 c.1764G>C synonymous_variant 0.21
clpC1 4038953 c.1752A>G synonymous_variant 0.25
clpC1 4038956 c.1749T>C synonymous_variant 0.27
clpC1 4038965 c.1740T>C synonymous_variant 0.24
clpC1 4038971 c.1734T>C synonymous_variant 0.23
clpC1 4038974 c.1731T>C synonymous_variant 0.23
clpC1 4038989 c.1716T>C synonymous_variant 0.22
clpC1 4038997 c.1708T>C synonymous_variant 0.21
clpC1 4039022 c.1683A>G synonymous_variant 0.26
clpC1 4039046 c.1659C>T synonymous_variant 0.27
clpC1 4039064 c.1641C>T synonymous_variant 0.22
clpC1 4039067 c.1638G>C synonymous_variant 0.2
clpC1 4039079 c.1626C>G synonymous_variant 0.24
clpC1 4039085 c.1620A>G synonymous_variant 0.26
clpC1 4039091 c.1614G>C synonymous_variant 0.26
clpC1 4039097 c.1608G>T synonymous_variant 0.18
clpC1 4039100 c.1605C>T synonymous_variant 0.16
clpC1 4039103 c.1602T>C synonymous_variant 0.15
clpC1 4039106 c.1599G>C synonymous_variant 0.16
clpC1 4039118 c.1587C>A synonymous_variant 0.18
clpC1 4039142 c.1563A>G synonymous_variant 0.26
clpC1 4039145 c.1560G>C synonymous_variant 0.27
clpC1 4039169 c.1536A>G synonymous_variant 0.31
clpC1 4039178 c.1527G>C synonymous_variant 0.3
clpC1 4039183 c.1522T>C synonymous_variant 0.29
clpC1 4039187 c.1518G>T synonymous_variant 0.3
clpC1 4039190 c.1515C>G synonymous_variant 0.33
clpC1 4039220 c.1485G>C synonymous_variant 0.43
clpC1 4039241 c.1464G>C synonymous_variant 0.38
clpC1 4039274 c.1431G>C synonymous_variant 0.35
clpC1 4039286 c.1419T>C synonymous_variant 0.38
clpC1 4039295 c.1410A>C synonymous_variant 0.38
clpC1 4039298 c.1407T>C synonymous_variant 0.37
clpC1 4039310 c.1395A>G synonymous_variant 0.33
clpC1 4039313 c.1392C>G synonymous_variant 0.31
clpC1 4039320 p.Ala462Gly missense_variant 0.27
clpC1 4039322 c.1383T>C synonymous_variant 0.25
clpC1 4039328 c.1377A>C synonymous_variant 0.25
clpC1 4039337 p.Thr456Gln missense_variant 0.2
clpC1 4039352 c.1353C>T synonymous_variant 0.28
clpC1 4039361 c.1344C>G synonymous_variant 0.26
clpC1 4039382 c.1323C>G synonymous_variant 0.17
clpC1 4039430 c.1275T>C synonymous_variant 0.19
clpC1 4039442 c.1263A>G synonymous_variant 0.18
clpC1 4039484 c.1221T>C synonymous_variant 0.14
clpC1 4039487 c.1218G>C synonymous_variant 0.18
clpC1 4039517 c.1188C>G synonymous_variant 0.38
clpC1 4039541 c.1164C>G synonymous_variant 0.38
clpC1 4039556 c.1149G>C synonymous_variant 0.41
clpC1 4039559 c.1146C>G synonymous_variant 0.41
clpC1 4039570 p.Met379Leu missense_variant 0.4
clpC1 4039574 p.Ala377Gly missense_variant 0.39
clpC1 4039577 c.1128T>C synonymous_variant 0.4
clpC1 4039589 c.1116G>C synonymous_variant 0.43
clpC1 4039592 c.1113G>C synonymous_variant 0.43
clpC1 4039610 c.1095G>C synonymous_variant 0.35
clpC1 4039616 c.1089G>C synonymous_variant 0.26
clpC1 4039622 c.1083C>T synonymous_variant 0.3
clpC1 4039649 c.1056G>C synonymous_variant 0.28
clpC1 4039652 c.1053G>C synonymous_variant 0.28
clpC1 4039670 c.1035G>C synonymous_variant 0.28
clpC1 4039682 c.1023C>G synonymous_variant 0.27
clpC1 4039694 c.1011G>C synonymous_variant 0.23
clpC1 4039724 c.981A>G synonymous_variant 0.26
clpC1 4039733 c.972G>C synonymous_variant 0.2
clpC1 4039742 c.963C>T synonymous_variant 0.16
clpC1 4039748 c.957G>C synonymous_variant 0.14
clpC1 4039751 c.954A>G synonymous_variant 0.16
clpC1 4039757 c.948A>G synonymous_variant 0.17
clpC1 4039760 c.945T>C synonymous_variant 0.15
clpC1 4039769 c.936C>G synonymous_variant 0.16
clpC1 4039793 c.912C>G synonymous_variant 0.15
clpC1 4039802 c.903G>C synonymous_variant 0.14
clpC1 4039823 c.882T>C synonymous_variant 0.14
clpC1 4039832 c.873C>A synonymous_variant 0.12
clpC1 4039850 c.855T>C synonymous_variant 0.16
clpC1 4039865 c.840T>C synonymous_variant 0.14
clpC1 4039883 c.822G>A synonymous_variant 0.17
clpC1 4039889 c.816G>C synonymous_variant 0.17
clpC1 4039898 c.807C>G synonymous_variant 0.17
clpC1 4039904 c.801A>G synonymous_variant 0.22
clpC1 4039931 c.774T>C synonymous_variant 0.18
clpC1 4039934 c.771G>A synonymous_variant 0.16
clpC1 4039937 c.768G>C synonymous_variant 0.16
clpC1 4039946 c.759A>T synonymous_variant 0.17
clpC1 4039949 c.756G>C synonymous_variant 0.17
clpC1 4039952 c.753T>C synonymous_variant 0.18
clpC1 4039958 c.747G>C synonymous_variant 0.23
clpC1 4039991 c.714G>C synonymous_variant 0.2
clpC1 4040003 c.702G>C synonymous_variant 0.18
clpC1 4040021 c.684A>C synonymous_variant 0.19
clpC1 4040024 c.681A>G synonymous_variant 0.19
clpC1 4040033 c.672G>C synonymous_variant 0.21
clpC1 4040042 c.663C>T synonymous_variant 0.2
clpC1 4040090 p.Ser205Thr missense_variant 0.12
clpC1 4040249 c.456A>G synonymous_variant 0.15
clpC1 4040258 c.447G>A synonymous_variant 0.15
clpC1 4040267 c.438A>G synonymous_variant 0.15
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.15
clpC1 4040279 c.426C>G synonymous_variant 0.17
clpC1 4040306 c.399G>T synonymous_variant 0.17
clpC1 4040309 c.396C>G synonymous_variant 0.17
clpC1 4040324 c.381G>C synonymous_variant 0.18
panD 4044165 c.117G>C synonymous_variant 0.14
panD 4044179 p.Ala35Thr missense_variant 0.15
panD 4044180 p.Asp34Glu missense_variant 0.15
panD 4044195 c.87T>C synonymous_variant 0.15
panD 4044210 c.72C>T synonymous_variant 0.14
panD 4044213 c.69C>G synonymous_variant 0.15
embC 4240717 c.855T>C synonymous_variant 0.16
embC 4240777 c.915G>A synonymous_variant 0.36
embC 4240780 c.918T>C synonymous_variant 0.36
embC 4240783 c.921G>C synonymous_variant 0.36
embC 4240789 c.927T>C synonymous_variant 0.35
embC 4240819 c.957A>C synonymous_variant 0.27
embC 4240828 c.966G>A synonymous_variant 0.27
embC 4240831 c.969T>G synonymous_variant 0.26
embC 4241611 c.1749G>C synonymous_variant 0.23
embC 4241614 c.1752A>C synonymous_variant 0.24
embC 4241626 c.1764T>C synonymous_variant 0.16
embC 4241635 c.1773G>C synonymous_variant 0.21
embC 4241644 c.1782G>C synonymous_variant 0.2
embC 4241648 c.1786T>C synonymous_variant 0.27
embC 4241656 c.1794G>A synonymous_variant 0.25
embC 4241659 c.1797G>C synonymous_variant 0.21
embC 4241665 c.1803G>T synonymous_variant 0.25
embC 4241668 c.1806G>C synonymous_variant 0.27
embC 4241671 c.1809T>G synonymous_variant 0.27
embC 4241691 p.Gly610Ala missense_variant 0.21
embC 4241695 c.1833T>G synonymous_variant 0.14
embA 4242550 c.-683C>G upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242872 p.Asp1004Thr missense_variant 0.15
embC 4242878 p.Thr1006Val missense_variant 0.17
embA 4245060 c.1828T>C synonymous_variant 0.13
embA 4245071 c.1839G>C synonymous_variant 0.14
embA 4245083 c.1851A>C synonymous_variant 0.14
embA 4245089 c.1857G>C synonymous_variant 0.14
embA 4245092 c.1860C>G synonymous_variant 0.14
embA 4245094 p.Ile621Thr missense_variant 0.14
embA 4245125 c.1893G>C synonymous_variant 0.12
embB 4247449 c.936C>T synonymous_variant 0.13
embB 4247455 c.942C>T synonymous_variant 0.13
embB 4247464 c.951C>G synonymous_variant 0.13
embB 4247470 c.957T>C synonymous_variant 0.14
embB 4247491 c.978G>C synonymous_variant 0.15
embB 4247497 c.984T>C synonymous_variant 0.12
embB 4248133 c.1620C>G synonymous_variant 0.13
embB 4248157 c.1644A>G synonymous_variant 0.2
embB 4248158 p.Cys549Ser missense_variant 0.2
embB 4248167 p.Thr552Ala missense_variant 0.2
embB 4248170 p.Ala553Ser missense_variant 0.21
embB 4248173 p.Val554Leu missense_variant 0.22
embB 4248199 c.1686A>G synonymous_variant 0.25
embB 4248200 p.Ile563Val missense_variant 0.25
embB 4248206 p.Ser565Gly missense_variant 0.29
embB 4248220 c.1707A>G synonymous_variant 0.26
embB 4248225 p.Ala571Val missense_variant 0.28
embB 4248233 c.1720C>T synonymous_variant 0.3
embB 4248242 p.Val577Ile missense_variant 0.3
embB 4248252 p.Gly580Ala missense_variant 0.24
embB 4248256 c.1743C>G synonymous_variant 0.24
embB 4248264 p.Phe584Cys missense_variant 0.25
embB 4248277 c.1764G>C synonymous_variant 0.2
aftB 4267272 p.Lys522Arg missense_variant 1.0
ethR 4326739 c.-810G>C upstream_gene_variant 1.0
ethA 4328004 c.-531C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0