Run ID: fe328f75-da18-4997-aebb-f03c9bdcabce
Sample name:
Date: 14-12-2023 16:17:33
Number of reads: 367713
Percentage reads mapped: 31.3
Median coverage: 13
Strain: lineage2.2.1
Spoligotype:
Drug-resistance: RR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage2 | East-Asian | RD105 | 0.99 |
| lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 0.98 |
| lineage2.2.1 | East-Asian (Beijing) | RD105;RD207;RD181 | 0.99 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | rpoB | p.Ser450Leu | Assoc w R | |
| isoniazid | ||||
| ethambutol | embB | p.Met306Val | Assoc w R | |
| pyrazinamide | pncA | p.Val130Gly | Assoc w R | |
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | rpsL | p.Lys43Arg | Assoc w R | |
| amikacin | rrs | n.1402C>A | Uncertain significance | |
| n.1484G>T | Assoc w R - interim | |||
| kanamycin | rrs | n.1402C>A | Uncertain significance | |
| n.1484G>T | Assoc w R | |||
| capreomycin | rrs | n.1402C>A | Uncertain significance | |
| n.1484G>T | Assoc w R | |||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rpoB | 761155 | p.Ser450Leu | missense_variant | 0.91 | rifampicin | Assoc w R | |
| rpsL | 781687 | p.Lys43Arg | missense_variant | 0.61 | streptomycin | Assoc w R | |
| rrs | 1473247 | n.1402C>A | non_coding_transcript_exon_variant | 0.79 | kanamycin | Uncertain significance | |
| capreomycin | Uncertain significance | ||||||
| aminoglycosides | Uncertain significance | ||||||
| amikacin | Uncertain significance | ||||||
| rrs | 1473329 | n.1484G>T | non_coding_transcript_exon_variant | 0.7 | kanamycin | Assoc w R | |
| capreomycin | Assoc w R | ||||||
| aminoglycosides | Uncertain significance | ||||||
| amikacin | Assoc w R - interim | ||||||
| pncA | 2288853 | p.Val130Gly | missense_variant | 1.0 | pyrazinamide | Assoc w R | |
| embB | 4247429 | p.Met306Val | missense_variant | 1.0 | ethambutol | Assoc w R |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 5509 | c.270C>A | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5557 | c.318C>A | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5995 | c.756C>T | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6117 | p.Trp293* | stop_gained | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6872 | p.Leu545Met | missense_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7030 | c.-272C>A | upstream_gene_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7630 | c.331delG | frameshift_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7763 | c.464delA | frameshift_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7943 | p.Glu214Asp | missense_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8271 | p.Ala324Ser | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8631 | p.Ala444Ser | missense_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9251 | c.1950G>A | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9723 | p.Glu808* | stop_gained | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| fgd1 | 491031 | c.249C>A | synonymous_variant | 0.11 | delamanid | |
| fgd1 | 491257 | p.Gly159Cys | missense_variant | 0.2 | delamanid | |
| fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | delamanid | |
| fgd1 | 491756 | p.Gln325Pro | missense_variant | 1.0 | delamanid | |
| mshA | 575244 | c.-104C>A | upstream_gene_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| mshA | 575907 | p.Ala187Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 576431 | p.Ala362Ser | missense_variant | 0.2 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619978 | p.Leu30Met | missense_variant | 0.2 | capreomycin | |
| amikacin | ||||||
| ccsA | 620075 | p.Gly62Val | missense_variant | 0.1 | capreomycin | |
| amikacin | ||||||
| ccsA | 620084 | p.Ala65Glu | missense_variant | 0.11 | capreomycin | |
| amikacin | ||||||
| ccsA | 620321 | p.Pro144Gln | missense_variant | 0.14 | capreomycin | |
| amikacin | ||||||
| ccsA | 620625 | p.Ile245Met | missense_variant | 1.0 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| rpoB | 759614 | c.-193C>A | upstream_gene_variant | 0.18 | rifampicin | |
| rpoB | 760823 | c.1017G>A | synonymous_variant | 0.1 | rifampicin | |
| rpoB | 761196 | c.1390_1391insA | frameshift_variant | 0.18 | rifampicin | |
| rpoB | 761829 | p.Gly675Cys | missense_variant | 0.12 | rifampicin | |
| rpoB | 762026 | c.2220G>T | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 762057 | p.Ile751Val | missense_variant | 0.15 | rifampicin | Uncertain significance |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 762146 | p.Glu780Asp | missense_variant | 0.17 | rifampicin | |
| rpoB | 762450 | p.Arg882Trp | missense_variant | 0.12 | rifampicin | |
| rpoC | 762617 | c.-753C>A | upstream_gene_variant | 0.12 | rifampicin | |
| rpoB | 762878 | p.Ile1024Met | missense_variant | 0.18 | rifampicin | |
| rpoB | 762879 | p.Met1025Leu | missense_variant | 0.18 | rifampicin | |
| rpoC | 762899 | c.-471G>T | upstream_gene_variant | 0.24 | rifampicin | |
| rpoC | 762920 | c.-450C>T | upstream_gene_variant | 0.21 | rifampicin | |
| rpoC | 762929 | c.-441G>C | upstream_gene_variant | 0.18 | rifampicin | |
| rpoC | 762959 | c.-411G>T | upstream_gene_variant | 0.19 | rifampicin | |
| rpoC | 762971 | c.-399G>C | upstream_gene_variant | 0.17 | rifampicin | |
| rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.18 | rifampicin | |
| rpoC | 762989 | c.-381G>A | upstream_gene_variant | 0.17 | rifampicin | |
| rpoC | 762995 | c.-375G>T | upstream_gene_variant | 0.17 | rifampicin | |
| rpoB | 763002 | c.3197dupA | frameshift_variant | 0.17 | rifampicin | |
| rpoB | 763006 | c.3201delC | frameshift_variant | 0.17 | rifampicin | |
| rpoB | 763017 | p.Gln1071Glu | missense_variant | 0.16 | rifampicin | |
| rpoC | 763031 | c.-339T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763058 | c.-312C>T | upstream_gene_variant | 0.1 | rifampicin | |
| rpoB | 763072 | c.3268_3270delACC | conservative_inframe_deletion | 0.12 | rifampicin | |
| rpoC | 763085 | c.-285C>T | upstream_gene_variant | 0.12 | rifampicin | |
| rpoC | 763094 | c.-276G>C | upstream_gene_variant | 0.21 | rifampicin | |
| rpoC | 763097 | c.-273C>T | upstream_gene_variant | 0.21 | rifampicin | |
| rpoC | 763115 | c.-255T>C | upstream_gene_variant | 0.11 | rifampicin | |
| rpoC | 763124 | c.-246C>T | upstream_gene_variant | 0.19 | rifampicin | |
| rpoC | 763127 | c.-243G>T | upstream_gene_variant | 0.19 | rifampicin | |
| rpoC | 763136 | c.-234C>T | upstream_gene_variant | 0.12 | rifampicin | |
| rpoC | 763498 | p.Lys43Asn | missense_variant | 0.13 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 763534 | c.165T>C | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 763537 | c.168C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.29 | rifampicin | |
| rpoC | 763570 | c.201G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 763573 | c.204G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 763622 | p.Ala85Ser | missense_variant | 0.18 | rifampicin | |
| rpoC | 763627 | p.Lys86Asn | missense_variant | 0.17 | rifampicin | |
| rpoC | 764089 | c.720C>A | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 764129 | p.Gly254Ser | missense_variant | 0.11 | rifampicin | Uncertain significance |
| rpoC | 764896 | c.1527C>T | synonymous_variant | 0.12 | rifampicin | |
| rpoC | 765258 | p.Arg630Gln | missense_variant | 0.13 | rifampicin | |
| rpoC | 765511 | c.2142C>T | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 765618 | p.Glu750Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766625 | p.Leu1086Met | missense_variant | 0.14 | rifampicin | |
| rpoC | 767212 | c.3843G>T | synonymous_variant | 0.2 | rifampicin | |
| mmpL5 | 775670 | c.2810delT | frameshift_variant | 0.2 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775743 | p.Gly913Asp | missense_variant | 0.14 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775771 | p.Ala904Ser | missense_variant | 0.15 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775803 | p.Met893Thr | missense_variant | 0.17 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776182 | p.Asp767Asn | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 777450 | p.Val344Asp | missense_variant | 0.18 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777835 | p.Ile216Phe | missense_variant | 0.17 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778010 | p.Gln157His | missense_variant | 0.12 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778085 | p.Asp132Glu | missense_variant | 0.14 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781403 | c.-157G>T | upstream_gene_variant | 0.18 | streptomycin | |
| rpsL | 781419 | c.-141G>T | upstream_gene_variant | 0.18 | streptomycin | |
| rpsL | 781444 | c.-116C>T | upstream_gene_variant | 0.14 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 0.12 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 0.18 | streptomycin | |
| rpsL | 781679 | c.120C>G | synonymous_variant | 0.39 | streptomycin | |
| rpsL | 781682 | c.123T>G | synonymous_variant | 0.39 | streptomycin | |
| rpsL | 781706 | c.147T>G | synonymous_variant | 0.2 | streptomycin | |
| rpsL | 781709 | c.150G>A | synonymous_variant | 0.2 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 0.18 | streptomycin | |
| rpsL | 781721 | c.162C>T | synonymous_variant | 0.18 | streptomycin | |
| rpsL | 781724 | c.166_172delAAGTTGA | frameshift_variant | 0.18 | streptomycin | |
| rpsL | 781734 | p.Ser59Pro | missense_variant | 0.16 | streptomycin | |
| rpsL | 781738 | p.Gln60Leu | missense_variant | 0.16 | streptomycin | |
| rpsL | 781742 | c.184_185insGGCATTG | frameshift_variant&stop_gained | 0.17 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 0.14 | streptomycin | |
| rpsL | 781757 | c.198C>T | synonymous_variant | 0.14 | streptomycin | |
| rpsL | 781766 | c.207C>T | synonymous_variant | 0.15 | streptomycin | |
| rpsL | 781768 | p.Glu70Val | missense_variant | 0.15 | streptomycin | |
| rpsL | 781772 | c.213C>A | synonymous_variant | 0.19 | streptomycin | |
| rpsL | 781781 | c.222G>C | synonymous_variant | 0.23 | streptomycin | |
| rpsL | 781793 | c.234G>C | synonymous_variant | 0.13 | streptomycin | |
| rpsL | 781802 | c.243G>T | synonymous_variant | 0.12 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.12 | streptomycin | |
| rpsL | 781814 | c.255C>T | synonymous_variant | 0.12 | streptomycin | |
| rpsL | 781817 | c.258G>T | synonymous_variant | 0.12 | streptomycin | |
| rpsL | 781829 | c.270G>C | synonymous_variant | 0.13 | streptomycin | |
| rpsL | 781832 | c.273T>G | synonymous_variant | 0.12 | streptomycin | |
| rpsL | 781841 | c.282C>T | synonymous_variant | 0.12 | streptomycin | |
| rplC | 801283 | p.Arg159Gly | missense_variant | 0.2 | linezolid | |
| fbiC | 1303079 | p.Ala50Glu | missense_variant | 0.12 | delamanid | |
| fbiC | 1303170 | c.240C>A | synonymous_variant | 0.17 | delamanid | |
| Rv1258c | 1406760 | c.580_581insC | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
| pyrazinamide | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv1258c | 1406921 | c.420C>T | synonymous_variant | 0.15 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| embR | 1416737 | p.Arg204Leu | missense_variant | 0.14 | ethambutol | Uncertain significance |
| embR | 1417439 | c.-92G>T | upstream_gene_variant | 0.17 | ethambutol | |
| atpE | 1460878 | c.-167C>A | upstream_gene_variant | 0.11 | bedaquiline | |
| atpE | 1461080 | c.36C>A | synonymous_variant | 0.18 | bedaquiline | |
| rrs | 1471936 | n.91A>G | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471951 | n.106G>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471967 | n.122G>A | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472009 | n.164T>G | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472107 | n.262A>G | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472112 | n.267C>T | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472122 | n.277G>T | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472123 | n.278A>T | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472124 | n.279C>T | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472160 | n.315C>T | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472225 | n.380C>G | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472240 | n.395G>A | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472251 | n.406G>C | non_coding_transcript_exon_variant | 0.63 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472279 | n.434T>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472285 | n.440A>G | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472288 | n.443A>T | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472289 | n.444T>G | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472290 | n.445C>T | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472324 | n.479G>A | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472325 | n.480G>T | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472326 | n.481T>G | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472329 | n.484A>T | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472330 | n.485G>A | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472368 | n.523A>G | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472396 | n.551A>T | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472400 | n.555C>T | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472412 | n.567A>G | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472427 | n.582T>G | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472428 | n.583G>A | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472435 | n.590T>C | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472437 | n.592T>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472438 | n.593T>A | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472439 | n.594C>A | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472443 | n.598A>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472449 | n.604C>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472450 | n.605A>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472451 | n.606C>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472460 | n.615T>C | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472461 | n.616G>C | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472471 | n.626G>T | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472472 | n.627G>T | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472473 | n.628G>T | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472483 | n.638C>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472484 | n.639A>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472489 | n.644A>T | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472493 | n.648T>G | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472495 | n.650C>A | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472496 | n.651T>G | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472507 | n.662C>A | non_coding_transcript_exon_variant | 0.71 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472522 | n.677T>G | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472557 | n.712G>A | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472571 | n.726G>T | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472581 | n.736A>C | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472582 | n.737G>T | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472584 | n.739A>T | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472585 | n.740A>C | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472623 | n.778A>C | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472647 | n.802C>T | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472673 | n.828T>G | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472675 | n.830T>C | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472677 | n.832C>A | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472682 | n.837T>A | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472683 | n.838T>C | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472687 | n.842A>T | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472707 | n.862A>T | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472767 | n.922G>C | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472812 | n.967A>T | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472837 | n.992C>G | non_coding_transcript_exon_variant | 0.55 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472843 | n.999_1001delCGC | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472860 | n.1015C>T | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472862 | n.1017_1018insGCC | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472865 | n.1020C>T | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472866 | n.1021C>T | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472870 | n.1025T>G | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472873 | n.1028C>T | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472875 | n.1030T>G | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472878 | n.1033G>T | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472879 | n.1034T>C | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472880 | n.1035G>A | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472894 | n.1049G>C | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472954 | n.1110delC | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472958 | n.1113_1114insC | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472986 | n.1141_1142insA | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472989 | n.1145delA | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472996 | n.1151T>C | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473038 | n.1193A>C | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473081 | n.1236C>T | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.71 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473091 | n.1246G>A | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473093 | n.1248C>T | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473094 | n.1249T>G | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473099 | n.1254T>G | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473100 | n.1255G>C | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473102 | n.1257C>T | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.71 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473109 | n.1264T>G | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473120 | n.1275C>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473122 | n.1277T>G | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473123 | n.1278A>G | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473164 | n.1319C>T | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473226 | n.1381C>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 0.8 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.77 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473288 | n.1443C>G | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473292 | n.1447G>T | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473294 | n.1449A>G | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473315 | n.1470T>C | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473319 | n.1474C>T | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473324 | n.1479G>A | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1474165 | n.508G>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1474166 | n.509G>T | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1474167 | n.510T>C | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| rrl | 1474197 | n.540C>T | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| rrl | 1474202 | n.545T>G | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| rrl | 1474218 | n.561T>G | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| rrl | 1474253 | n.596A>T | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1474264 | n.607T>G | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474265 | n.608G>T | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474266 | n.609T>C | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474269 | n.612C>A | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474271 | n.614A>G | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474275 | n.618T>G | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474454 | n.797G>A | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1474467 | n.810A>T | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474476 | n.819C>T | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| rrl | 1474488 | n.831G>A | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| rrl | 1474496 | n.839C>T | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| rrl | 1474497 | n.840G>C | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| rrl | 1474506 | n.849C>G | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| rrl | 1474507 | n.850G>T | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| rrl | 1474516 | n.859C>T | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| rrl | 1474529 | n.872A>C | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| rrl | 1474530 | n.873G>A | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| rrl | 1474539 | n.882C>T | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| rrl | 1474540 | n.883T>G | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1474558 | n.901G>A | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| rrl | 1474582 | n.925T>A | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1474639 | n.982G>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1474640 | n.983C>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1474651 | n.995delT | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1474662 | n.1005C>T | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474664 | n.1007G>T | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474666 | n.1009T>G | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474670 | n.1013C>G | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474672 | n.1015C>T | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474675 | n.1018C>T | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474676 | n.1019T>C | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474677 | n.1020A>G | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474679 | n.1022G>C | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474684 | n.1027T>C | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474687 | n.1030C>A | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474688 | n.1031G>A | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474707 | n.1051_1052delCG | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| rrl | 1474711 | n.1055_1056insCAAG | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| rrl | 1474715 | n.1060_1061delAA | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474752 | n.1096delA | non_coding_transcript_exon_variant | 0.61 | linezolid | |
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| rrl | 1474779 | n.1122G>A | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| rrl | 1474780 | n.1123C>T | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| rrl | 1474782 | n.1125G>A | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.55 | linezolid | |
| rrl | 1474798 | n.1141C>T | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1474799 | n.1143delT | non_coding_transcript_exon_variant | 0.52 | linezolid | |
| rrl | 1474803 | n.1146_1147insA | non_coding_transcript_exon_variant | 0.52 | linezolid | |
| rrl | 1474806 | n.1149A>C | non_coding_transcript_exon_variant | 0.52 | linezolid | |
| rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| rrl | 1474827 | n.1170C>T | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1474831 | n.1174A>T | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1474853 | n.1196A>G | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.48 | linezolid | |
| rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474905 | n.1248T>C | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1475074 | n.1417A>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1475699 | n.2042C>T | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| rrl | 1475722 | n.2065G>T | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| rrl | 1475747 | n.2090A>G | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| rrl | 1475751 | n.2094C>A | non_coding_transcript_exon_variant | 0.88 | linezolid | |
| rrl | 1475753 | n.2096C>T | non_coding_transcript_exon_variant | 0.88 | linezolid | |
| rrl | 1475767 | n.2110G>T | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1475777 | n.2120A>T | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| rrl | 1475781 | n.2124T>C | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| rrl | 1475869 | n.2212C>A | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1475877 | n.2220C>T | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| rrl | 1475883 | n.2226A>T | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| rrl | 1475892 | n.2235A>C | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1475906 | n.2249C>T | non_coding_transcript_exon_variant | 0.85 | linezolid | Uncertain significance |
| rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| rrl | 1475943 | n.2286G>A | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| rrl | 1475952 | n.2295A>G | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1475953 | n.2296A>G | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1475970 | n.2313C>T | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1475978 | n.2321C>T | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.84 | linezolid | Uncertain significance |
| rrl | 1475991 | n.2334T>A | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1475993 | n.2336C>T | non_coding_transcript_exon_variant | 0.83 | linezolid | Uncertain significance |
| rrl | 1475996 | n.2339T>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476141 | n.2484A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476153 | n.2496T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476164 | n.2507A>G | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1476165 | n.2508T>G | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.86 | linezolid | Uncertain significance |
| rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476204 | n.2547C>T | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| rrl | 1476235 | n.2578A>G | non_coding_transcript_exon_variant | 0.88 | linezolid | |
| rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.88 | linezolid | |
| rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| rrl | 1476256 | n.2599A>G | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.87 | linezolid | Uncertain significance |
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| rrl | 1476288 | n.2635_2643delGCACCCCCG | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 0.81 | linezolid | Uncertain significance |
| rrl | 1476301 | n.2644_2645insCGGTGGCTT | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1476307 | n.2650A>T | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1476309 | n.2652G>C | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| rrl | 1476312 | n.2655T>C | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| rrl | 1476316 | n.2659G>A | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476363 | n.2706A>G | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| rrl | 1476366 | n.2709A>C | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1476368 | n.2711T>C | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1476374 | n.2717T>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| rrl | 1476515 | n.2858C>T | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| fabG1 | 1673183 | c.-257T>C | upstream_gene_variant | 0.14 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673346 | c.-94C>A | upstream_gene_variant | 0.18 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674264 | c.63C>A | synonymous_variant | 0.2 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833578 | p.Val13Phe | missense_variant | 0.12 | pyrazinamide | |
| rpsA | 1833794 | p.Glu85* | stop_gained | 0.11 | pyrazinamide | |
| rpsA | 1833952 | c.411C>A | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1833955 | c.414G>T | synonymous_variant | 0.29 | pyrazinamide | |
| rpsA | 1833958 | c.417C>T | synonymous_variant | 0.29 | pyrazinamide | |
| rpsA | 1833959 | p.Leu140Val | missense_variant | 0.29 | pyrazinamide | |
| rpsA | 1833970 | c.429G>C | synonymous_variant | 0.35 | pyrazinamide | |
| rpsA | 1833973 | c.432G>T | synonymous_variant | 0.12 | pyrazinamide | |
| rpsA | 1833976 | c.435C>T | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833985 | c.444G>T | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833994 | c.453G>T | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1833997 | c.456G>T | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1834000 | c.459G>T | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834012 | c.471G>A | synonymous_variant | 0.5 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 0.5 | pyrazinamide | |
| rpsA | 1834018 | c.477C>T | synonymous_variant | 0.53 | pyrazinamide | |
| rpsA | 1834024 | c.483G>C | synonymous_variant | 0.53 | pyrazinamide | |
| rpsA | 1834034 | p.Ile165Val | missense_variant | 0.5 | pyrazinamide | |
| rpsA | 1834039 | c.498C>T | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834040 | p.Lys167Gln | missense_variant | 0.4 | pyrazinamide | |
| rpsA | 1834069 | c.528G>C | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834090 | c.549G>T | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834099 | c.558C>G | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1834105 | c.564C>T | synonymous_variant | 0.32 | pyrazinamide | |
| rpsA | 1834108 | c.567C>G | synonymous_variant | 0.32 | pyrazinamide | |
| rpsA | 1834114 | c.573G>C | synonymous_variant | 0.29 | pyrazinamide | |
| rpsA | 1834123 | c.582C>T | synonymous_variant | 0.32 | pyrazinamide | |
| rpsA | 1834129 | c.588C>T | synonymous_variant | 0.12 | pyrazinamide | |
| rpsA | 1834168 | c.627C>A | synonymous_variant | 0.12 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834183 | c.642T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 0.23 | pyrazinamide | |
| rpsA | 1834210 | c.669C>T | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834213 | c.672G>C | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834216 | c.675C>T | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834219 | c.678C>T | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 0.26 | pyrazinamide | |
| rpsA | 1834241 | c.700_702delCTGinsTTA | synonymous_variant | 0.26 | pyrazinamide | |
| rpsA | 1834246 | c.705G>C | synonymous_variant | 0.26 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 0.25 | pyrazinamide | |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 0.25 | pyrazinamide | |
| rpsA | 1834273 | c.732C>T | synonymous_variant | 0.25 | pyrazinamide | |
| rpsA | 1834286 | c.745_746delTCinsAG | synonymous_variant | 0.26 | pyrazinamide | |
| rpsA | 1834294 | c.753G>C | synonymous_variant | 0.26 | pyrazinamide | |
| rpsA | 1834298 | p.Gln253Glu | missense_variant | 0.26 | pyrazinamide | |
| rpsA | 1834307 | p.Asp256Gln | missense_variant | 0.27 | pyrazinamide | |
| rpsA | 1834310 | p.Glu257Pro | missense_variant | 0.27 | pyrazinamide | |
| rpsA | 1834318 | c.777C>T | synonymous_variant | 0.26 | pyrazinamide | |
| rpsA | 1834330 | c.789C>G | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834345 | c.804C>T | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834354 | c.813G>C | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834357 | c.816T>C | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834361 | c.820T>C | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834366 | c.825A>T | synonymous_variant | 0.27 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834455 | p.Val305Ala | missense_variant | 0.12 | pyrazinamide | |
| rpsA | 1834464 | p.Gly308Val | missense_variant | 0.13 | pyrazinamide | |
| tlyA | 1917828 | c.-112G>T | upstream_gene_variant | 0.12 | capreomycin | |
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918099 | p.Val54Met | missense_variant | 0.11 | capreomycin | |
| tlyA | 1918205 | p.Ala89Glu | missense_variant | 0.15 | capreomycin | |
| ndh | 2101958 | p.Phe362Ser | missense_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102107 | c.936C>A | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102137 | c.906G>T | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| ndh | 2102231 | p.Ser271* | stop_gained | 0.2 | ethionamide | |
| isoniazid | ||||||
| katG | 2155627 | p.Ala162Glu | missense_variant | 0.11 | isoniazid | Uncertain significance |
| katG | 2155957 | p.Pro52Gln | missense_variant | 0.18 | isoniazid | |
| katG | 2156498 | c.-387A>G | upstream_gene_variant | 0.13 | isoniazid | |
| PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| PPE35 | 2169179 | c.1434C>A | synonymous_variant | 0.18 | pyrazinamide | |
| PPE35 | 2169824 | c.788delG | frameshift_variant | 0.15 | pyrazinamide | |
| PPE35 | 2169913 | p.Asn234Tyr | missense_variant | 0.14 | pyrazinamide | |
| Rv1979c | 2222758 | p.Val136Ala | missense_variant | 0.11 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| Rv1979c | 2223337 | c.-173C>T | upstream_gene_variant | 0.14 | clofazimine | |
| bedaquiline | ||||||
| pncA | 2288884 | p.Leu120Met | missense_variant | 0.11 | pyrazinamide | |
| pncA | 2289349 | c.-108C>A | upstream_gene_variant | 0.18 | pyrazinamide | |
| pncA | 2289400 | c.-159T>A | upstream_gene_variant | 0.15 | pyrazinamide | |
| pncA | 2289547 | c.-306G>T | upstream_gene_variant | 0.18 | pyrazinamide | |
| pncA | 2289576 | c.-335C>T | upstream_gene_variant | 0.15 | pyrazinamide | |
| pncA | 2289766 | c.-525T>A | upstream_gene_variant | 0.13 | pyrazinamide | |
| pncA | 2289831 | c.-590A>G | upstream_gene_variant | 0.1 | pyrazinamide | |
| kasA | 2518566 | p.Ala151Val | missense_variant | 0.11 | isoniazid | |
| kasA | 2518901 | p.Ala263Ser | missense_variant | 0.11 | isoniazid | |
| kasA | 2519280 | p.Pro389Gln | missense_variant | 0.15 | isoniazid | |
| eis | 2714332 | p.Gly334Val | missense_variant | 0.11 | kanamycin | |
| amikacin | ||||||
| eis | 2715290 | p.Gly15Trp | missense_variant | 0.12 | kanamycin | |
| amikacin | ||||||
| ahpC | 2725969 | c.-224C>A | upstream_gene_variant | 0.15 | isoniazid | |
| folC | 2747441 | p.Leu53Ser | missense_variant | 0.18 | para-aminosalicylic_acid | |
| ribD | 2986841 | c.3G>T | start_lost | 0.18 | para-aminosalicylic_acid | |
| ribD | 2987028 | p.Gly64Trp | missense_variant | 0.13 | para-aminosalicylic_acid | |
| Rv2752c | 3064874 | p.Gly440Ser | missense_variant | 0.11 | rifampicin | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065276 | p.Gly306Cys | missense_variant | 0.12 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065559 | c.633C>T | synonymous_variant | 0.12 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3066294 | c.-103C>A | upstream_gene_variant | 0.18 | rifampicin | |
| isoniazid | ||||||
| thyA | 3073689 | c.783C>A | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
| ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
| ald | 3086868 | p.Ala17Ser | missense_variant | 0.2 | cycloserine | |
| ald | 3087075 | p.Arg86Gly | missense_variant | 0.11 | cycloserine | |
| ald | 3087279 | p.Gly154Trp | missense_variant | 0.12 | cycloserine | |
| ald | 3087461 | c.642G>A | synonymous_variant | 0.11 | cycloserine | |
| fbiD | 3339402 | c.285C>A | synonymous_variant | 0.15 | delamanid | |
| fbiD | 3339704 | p.Thr196Lys | missense_variant | 0.2 | delamanid | |
| Rv3083 | 3448627 | p.Gly42Cys | missense_variant | 0.14 | ethionamide | |
| fprA | 3474351 | c.345C>A | synonymous_variant | 0.15 | capreomycin | |
| amikacin | ||||||
| whiB7 | 3568551 | p.Cys43* | stop_gained | 0.12 | streptomycin | |
| kanamycin | ||||||
| amikacin | ||||||
| whiB7 | 3568556 | p.Leu42Met | missense_variant | 0.12 | streptomycin | |
| kanamycin | ||||||
| amikacin | ||||||
| whiB7 | 3568648 | p.Pro11His | missense_variant | 0.12 | streptomycin | |
| kanamycin | ||||||
| amikacin | ||||||
| Rv3236c | 3612750 | p.Gly123Trp | missense_variant | 0.1 | pyrazinamide | |
| Rv3236c | 3612813 | p.Thr102Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| fbiA | 3641447 | p.Thr302Met | missense_variant | 0.15 | delamanid | Uncertain significance |
| fbiB | 3642168 | p.Thr212Ser | missense_variant | 0.15 | delamanid | |
| fbiB | 3642390 | p.Ala286Ser | missense_variant | 0.11 | delamanid | |
| fbiB | 3642755 | c.1221G>A | synonymous_variant | 0.15 | delamanid | |
| alr | 3840413 | c.1008C>A | synonymous_variant | 0.13 | cycloserine | |
| rpoA | 3877962 | c.546G>A | synonymous_variant | 0.13 | rifampicin | |
| ddn | 3987152 | c.309A>G | synonymous_variant | 0.13 | delamanid | |
| clpC1 | 4038435 | p.Ala757Glu | missense_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039006 | p.Ala567Thr | missense_variant | 0.17 | pyrazinamide | |
| clpC1 | 4039164 | p.Leu514Pro | missense_variant | 0.11 | pyrazinamide | |
| clpC1 | 4040107 | p.Val200Leu | missense_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040110 | c.595C>A | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4040138 | c.567G>A | synonymous_variant | 0.17 | pyrazinamide | |
| panD | 4044059 | p.Ala75Thr | missense_variant | 0.15 | pyrazinamide | |
| embC | 4239871 | c.9C>T | synonymous_variant | 0.14 | ethambutol | |
| embC | 4239893 | p.Ala11Ser | missense_variant | 0.12 | ethambutol | |
| embC | 4239966 | p.Val35Ala | missense_variant | 0.18 | ethambutol | |
| embC | 4239985 | c.123T>G | synonymous_variant | 0.11 | ethambutol | |
| embC | 4240396 | p.Glu178Asp | missense_variant | 0.18 | ethambutol | |
| embC | 4241159 | p.Ala433Ser | missense_variant | 0.1 | ethambutol | |
| embC | 4242552 | p.Arg897Leu | missense_variant | 0.17 | ethambutol | |
| embC | 4242569 | p.Asp903Asn | missense_variant | 0.17 | ethambutol | |
| embA | 4243087 | c.-146G>T | upstream_gene_variant | 0.12 | ethambutol | |
| embA | 4243460 | c.228C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4243606 | c.378_380delGGC | disruptive_inframe_deletion | 0.12 | ethambutol | |
| embA | 4243673 | c.441C>A | synonymous_variant | 0.1 | ethambutol | |
| embA | 4244420 | c.1188G>T | synonymous_variant | 0.18 | ethambutol | |
| embA | 4244451 | p.Pro407Thr | missense_variant | 0.2 | ethambutol | |
| embB | 4246376 | c.-138G>T | upstream_gene_variant | 0.12 | ethambutol | |
| embB | 4246439 | c.-75T>A | upstream_gene_variant | 0.13 | ethambutol | |
| embB | 4247017 | c.504G>T | synonymous_variant | 0.15 | ethambutol | |
| embB | 4247771 | p.Glu420* | stop_gained | 0.13 | ethambutol | |
| embB | 4248116 | p.Gly535Ser | missense_variant | 0.12 | ethambutol | Uncertain significance |
| embB | 4248631 | c.2118G>T | synonymous_variant | 0.18 | ethambutol | |
| embB | 4248952 | c.2439C>T | synonymous_variant | 0.14 | ethambutol | |
| aftB | 4267215 | p.Gly541Val | missense_variant | 0.1 | capreomycin | |
| amikacin | ||||||
| aftB | 4267291 | p.Ala516Thr | missense_variant | 0.11 | capreomycin | |
| amikacin | ||||||
| ubiA | 4269178 | p.Arg219Pro | missense_variant | 0.2 | ethambutol | |
| ubiA | 4269727 | p.Pro36Leu | missense_variant | 0.14 | ethambutol | |
| ethA | 4326426 | p.Gly350Cys | missense_variant | 0.18 | ethionamide | Uncertain significance |
| ethR | 4326847 | c.-702G>T | upstream_gene_variant | 0.17 | ethionamide | |
| ethA | 4326881 | p.Gly198Asp | missense_variant | 0.13 | ethionamide | |
| ethA | 4327341 | p.Trp45Arg | missense_variant | 1.0 | ethionamide | |
| ethA | 4327689 | c.-216G>A | upstream_gene_variant | 0.18 | ethionamide | |
| whiB6 | 4338229 | p.Leu98Pro | missense_variant | 0.13 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | ||||||
| whiB6 | 4338255 | c.267A>G | synonymous_variant | 0.13 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338365 | p.Cys53Arg | missense_variant | 1.0 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| gid | 4407927 | p.Glu92Asp | missense_variant | 1.0 | streptomycin | Uncertain significance |
| gid | 4408105 | p.Arg33Leu | missense_variant | 0.15 | streptomycin | |
| gid | 4408267 | c.-65T>C | upstream_gene_variant | 0.14 | streptomycin | Uncertain significance |
