TB-Profiler result

Run: ERR4817915
Summary

Run ID: ERR4817915

Sample name:

Date: 01-04-2023 15:15:44

Number of reads: 54110

Percentage reads mapped: 1.6

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 1.0 rifampicin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.99 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.98 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6811 c.-491C>T upstream_gene_variant 1.0
gyrA 6826 c.-476G>C upstream_gene_variant 1.0
gyrA 6841 c.-461T>C upstream_gene_variant 1.0
gyrA 6844 c.-458T>C upstream_gene_variant 0.92
gyrA 6853 c.-449A>G upstream_gene_variant 1.0
gyrA 6856 c.-446T>C upstream_gene_variant 1.0
gyrA 6859 c.-443T>C upstream_gene_variant 1.0
gyrB 6860 p.Ser541Thr missense_variant 1.0
gyrA 6869 c.-433T>C upstream_gene_variant 1.0
gyrA 6872 c.-430_-428delTTGinsCTC upstream_gene_variant 1.0
gyrA 6877 c.-425G>C upstream_gene_variant 1.0
gyrA 6878 c.-424T>C upstream_gene_variant 1.0
gyrA 6881 c.-421T>C upstream_gene_variant 1.0
gyrA 6889 c.-413G>C upstream_gene_variant 1.0
gyrB 6912 p.Asn558Ile missense_variant 1.0
gyrA 7366 p.Gln22Leu missense_variant 1.0
gyrA 7380 c.79_81delAGCinsTCG synonymous_variant 1.0
gyrA 7386 p.Ile29Leu missense_variant 1.0
gyrA 7394 c.93T>C synonymous_variant 1.0
gyrA 7415 c.114C>G synonymous_variant 1.0
gyrA 7427 c.126G>C synonymous_variant 1.0
gyrA 7430 p.Glu43Asp missense_variant 1.0
gyrA 7433 c.132G>C synonymous_variant 1.0
gyrA 7442 c.141G>C synonymous_variant 1.0
gyrA 7445 c.144C>G synonymous_variant 1.0
gyrA 7451 c.150C>G synonymous_variant 1.0
gyrA 7457 c.156T>C synonymous_variant 1.0
gyrA 7463 c.162G>C synonymous_variant 1.0
gyrA 7467 p.Leu56Ile missense_variant 1.0
gyrA 8294 c.993T>G synonymous_variant 1.0
gyrA 8316 p.Thr339Glu missense_variant 1.0
gyrA 8320 p.Ser340Asn missense_variant 1.0
gyrA 8324 c.1023T>C synonymous_variant 1.0
gyrA 8330 c.1029C>G synonymous_variant 1.0
gyrA 8339 c.1038A>C synonymous_variant 1.0
gyrA 8354 c.1053G>C synonymous_variant 1.0
rpoB 761027 c.1221A>C synonymous_variant 1.0
rpoB 761036 c.1230G>C synonymous_variant 1.0
rpoB 761037 c.1231T>C synonymous_variant 1.0
rpoB 761046 p.Ile414Val missense_variant 1.0
rpoB 761051 c.1245G>A synonymous_variant 1.0
rpoB 761054 c.1248G>C synonymous_variant 1.0
rpoB 761057 c.1251G>C synonymous_variant 1.0
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 1.0
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0
rpoB 761102 c.1296A>G synonymous_variant 1.0
rpoB 761132 c.1326G>C synonymous_variant 1.0
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 1.0
rpoB 761150 c.1344A>C synonymous_variant 1.0
rpoB 761153 c.1347G>C synonymous_variant 1.0
rpoB 761162 c.1356G>C synonymous_variant 1.0
rpoB 761165 c.1359G>C synonymous_variant 1.0
rpoB 762140 c.2334G>C synonymous_variant 1.0
rpoB 762143 c.2337T>C synonymous_variant 1.0
rpoB 762149 c.2343G>C synonymous_variant 1.0
rpoB 762156 p.Val784Ile missense_variant 1.0
rpoB 762167 c.2361T>C synonymous_variant 0.67
rpoB 762176 c.2370T>C synonymous_variant 1.0
rpoB 762180 p.Asp792Pro missense_variant 0.67
rpoB 762185 c.2379G>C synonymous_variant 1.0
rpoB 762194 c.2388G>C synonymous_variant 0.67
rpoB 762209 c.2403C>G synonymous_variant 0.67
rpoB 762218 c.2412T>C synonymous_variant 1.0
rpoB 762426 p.Ser874Thr missense_variant 1.0
rpoB 762431 p.Asp875Glu missense_variant 1.0
rpoC 762434 c.-936T>C upstream_gene_variant 1.0
rpoC 762443 c.-927G>C upstream_gene_variant 1.0
rpoC 762452 c.-918G>C upstream_gene_variant 1.0
rpoC 762470 c.-900G>C upstream_gene_variant 1.0
rpoB 762474 p.Gly890Ser missense_variant 1.0
rpoC 762491 c.-879T>C upstream_gene_variant 0.67
rpoC 762509 c.-861T>C upstream_gene_variant 1.0
rpoC 762512 c.-858C>G upstream_gene_variant 1.0
rpoC 762854 c.-516G>C upstream_gene_variant 0.95
rpoC 762857 c.-513C>G upstream_gene_variant 1.0
rpoB 762858 p.Thr1018Ser missense_variant 1.0
rpoC 762863 c.-507T>C upstream_gene_variant 1.0
rpoB 762879 p.Met1025Leu missense_variant 1.0
rpoC 762896 c.-474G>C upstream_gene_variant 0.98
rpoC 762929 c.-441G>C upstream_gene_variant 1.0
rpoC 762932 c.-438G>C upstream_gene_variant 0.98
rpoC 762947 c.-423C>G upstream_gene_variant 1.0
rpoC 762962 c.-408C>T upstream_gene_variant 1.0
rpoC 762980 c.-390T>C upstream_gene_variant 0.95
rpoC 762989 c.-381G>C upstream_gene_variant 1.0
rpoC 762995 c.-375G>C upstream_gene_variant 1.0
rpoB 763005 p.Cys1067Gly missense_variant 0.67
rpoC 763022 c.-348C>G upstream_gene_variant 1.0
rpoC 763028 c.-342T>C upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763058 c.-312C>G upstream_gene_variant 0.67
rpoC 763070 c.-300T>C upstream_gene_variant 1.0
rpoB 763075 p.Thr1090Ile missense_variant 1.0
rpoB 763077 p.Val1091Leu missense_variant 0.92
rpoC 763094 c.-276G>C upstream_gene_variant 0.92
rpoC 763115 c.-255T>C upstream_gene_variant 1.0
rpoB 763126 p.Pro1107Gln missense_variant 1.0
rpoC 763133 c.-237G>C upstream_gene_variant 1.0
rpoC 763160 c.-210G>C upstream_gene_variant 1.0
rpoB 763161 p.Leu1119Met missense_variant 1.0
rpoC 763166 c.-204A>G upstream_gene_variant 1.0
rpoC 763169 c.-201A>G upstream_gene_variant 1.0
rpoB 763170 p.Leu1122Met missense_variant 1.0
rpoC 763181 c.-189G>C upstream_gene_variant 1.0
rpoC 763187 c.-183C>G upstream_gene_variant 1.0
rpoC 763468 c.99G>C synonymous_variant 1.0
rpoC 763486 c.117T>G synonymous_variant 1.0
rpoC 763492 c.123G>C synonymous_variant 1.0
rpoC 763504 c.135C>G synonymous_variant 0.88
rpoC 763507 c.138G>C synonymous_variant 0.88
rpoC 763511 p.Cys48Gly missense_variant 0.88
rpoC 763517 p.Lys50Gln missense_variant 0.88
rpoC 763532 p.Thr55Ser missense_variant 0.88
rpoC 763537 c.168C>T synonymous_variant 0.88
rpoC 763546 c.177A>G synonymous_variant 1.0
rpoC 763550 p.Tyr61Ala missense_variant 0.88
rpoC 763570 c.201G>C synonymous_variant 1.0
rpoC 763573 c.204G>C synonymous_variant 1.0
rpoC 763660 c.291T>C synonymous_variant 1.0
rpoC 763666 c.297G>C synonymous_variant 1.0
rpoC 763669 c.300C>G synonymous_variant 0.93
rpoC 763672 c.303C>G synonymous_variant 0.93
rpoC 763675 c.306C>G synonymous_variant 0.94
rpoC 763696 c.327T>C synonymous_variant 1.0
rpoC 763699 c.330G>C synonymous_variant 1.0
rpoC 763708 c.339G>C synonymous_variant 1.0
rpoC 763711 c.342G>C synonymous_variant 0.94
rpoC 763714 c.345G>C synonymous_variant 1.0
rpoC 763717 c.348T>C synonymous_variant 1.0
rpoC 763723 c.354G>C synonymous_variant 0.94
rpoC 763727 p.Leu120Met missense_variant 0.94
rpoC 763732 c.363C>G synonymous_variant 1.0
rpoC 763744 c.375G>C synonymous_variant 1.0
rpoC 763751 p.Ile128Val missense_variant 0.94
rpoC 763765 c.396T>C synonymous_variant 1.0
rpoC 764316 p.Ala316Val missense_variant 0.93
rpoC 764320 c.951C>G synonymous_variant 1.0
rpoC 764353 c.984G>C synonymous_variant 1.0
rpoC 764365 c.996C>T synonymous_variant 1.0
rpoC 764371 c.1002G>C synonymous_variant 1.0
rpoC 764377 c.1008C>G synonymous_variant 0.96
rpoC 764380 c.1011G>C synonymous_variant 0.96
rpoC 764387 c.1018T>C synonymous_variant 1.0
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0
rpoC 764410 c.1041G>C synonymous_variant 1.0
rpoC 764419 c.1050C>G synonymous_variant 1.0
rpoC 764587 c.1218C>G synonymous_variant 0.67
rpoC 764602 c.1233C>T synonymous_variant 0.88
rpoC 764605 c.1236G>C synonymous_variant 0.88
rpoC 764611 c.1242G>C synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764650 c.1281G>T synonymous_variant 1.0
rpoC 764662 c.1293G>C synonymous_variant 1.0
rpoC 764677 c.1308C>G synonymous_variant 0.98
rpoC 764706 p.Leu446Gln missense_variant 1.0
rpoC 764722 c.1353G>C synonymous_variant 1.0
rpoC 764740 p.Met457Ile missense_variant 1.0
rpoC 764746 c.1377G>C synonymous_variant 1.0
rpoC 764749 c.1380G>C synonymous_variant 1.0
rpoC 764750 p.Val461Ile missense_variant 1.0
rpoC 764758 c.1389C>G synonymous_variant 1.0
rpoC 764760 p.Asn464Ser missense_variant 1.0
rpoC 764764 c.1395T>C synonymous_variant 1.0
rpoC 764780 p.Ser471Ala missense_variant 1.0
rpoC 764797 c.1428G>C synonymous_variant 1.0
rpoC 764815 c.1446A>G synonymous_variant 1.0
rpoC 764824 c.1455T>C synonymous_variant 1.0
rpoC 764854 c.1485G>C synonymous_variant 1.0
rpoC 764858 c.1489T>C synonymous_variant 1.0
rpoC 765886 c.2517C>G synonymous_variant 1.0
rpoC 765892 c.2523T>C synonymous_variant 1.0
rpoC 765904 c.2535C>G synonymous_variant 1.0
rpoC 765934 c.2565C>T synonymous_variant 0.4
rpoC 765937 c.2568T>C synonymous_variant 0.6
rpoC 765940 c.2571A>C synonymous_variant 1.0
rpoC 765946 c.2577C>T synonymous_variant 1.0
rpoC 765947 c.2578T>C synonymous_variant 1.0
rpoC 765952 c.2583G>C synonymous_variant 1.0
rpoC 765955 c.2586C>T synonymous_variant 0.4
rpoC 765958 c.2589C>G synonymous_variant 0.6
rpoC 765962 c.2593_2595delTTGinsCTC synonymous_variant 1.0
rpoC 765973 c.2604C>G synonymous_variant 0.6
rpoC 765979 c.2610C>G synonymous_variant 0.4
rpoC 765994 c.2625A>T synonymous_variant 1.0
rpoC 766000 c.2631G>C synonymous_variant 0.75
rpoC 766003 c.2634G>C synonymous_variant 0.75
rpoC 766009 c.2640G>C synonymous_variant 1.0
rpoC 766012 c.2643C>G synonymous_variant 1.0
rpoC 766021 c.2652G>C synonymous_variant 1.0
rpsL 781751 c.192G>C synonymous_variant 1.0
rpsL 781754 c.195G>C synonymous_variant 1.0
rpsL 781760 c.201T>C synonymous_variant 1.0
rpsL 781802 c.243G>C synonymous_variant 0.97
rpsL 781817 c.258G>T synonymous_variant 0.97
rpsL 781829 c.270G>C synonymous_variant 0.98
rpsL 781832 c.273T>C synonymous_variant 0.97
rpsL 781835 c.276T>C synonymous_variant 0.86
rpsL 781859 c.300T>C synonymous_variant 0.75
rpsL 781860 p.Ser101Ala missense_variant 0.75
rpsL 781865 c.306G>C synonymous_variant 0.96
rpsL 781868 c.309T>C synonymous_variant 0.8
rpsL 781876 p.Gly106Ala missense_variant 0.83
rpsL 781880 c.321C>G synonymous_variant 0.86
rpsL 781892 c.333A>G synonymous_variant 0.95
rpsL 781898 c.339A>T synonymous_variant 1.0
rpsL 781901 c.342C>T synonymous_variant 1.0
rpsL 781907 c.348T>C synonymous_variant 1.0
rpsL 781916 c.357T>G synonymous_variant 1.0
rpsL 781921 p.Lys121Met missense_variant 0.82
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.67
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.94
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.94
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.94
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.97
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.96
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 1.0
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 1.0
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 1.0
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 1.0
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.94
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.95
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.95
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.95
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 1.0
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 1.0
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.73
rrs 1472495 n.650C>G non_coding_transcript_exon_variant 0.73
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.97
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.97
rrs 1472582 n.737G>C non_coding_transcript_exon_variant 0.97
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.97
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.91
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.88
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.88
rrs 1472666 n.821G>A non_coding_transcript_exon_variant 0.83
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.67
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.67
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.67
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.67
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 1.0
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 1.0
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.67
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.67
rrs 1472694 n.849C>T non_coding_transcript_exon_variant 0.93
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.98
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.98
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.99
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 1.0
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.98
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.99
rrs 1472956 n.1111T>G non_coding_transcript_exon_variant 0.99
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.99
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.98
rrs 1472990 n.1145A>T non_coding_transcript_exon_variant 0.98
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.98
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.99
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.99
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.98
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.97
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.97
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.97
rrs 1473109 n.1264T>C non_coding_transcript_exon_variant 0.97
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 1.0
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.98
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.97
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.97
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.99
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.99
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.99
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.99
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 1.0
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 1.0
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 1.0
rrl 1473828 n.173_174delTG non_coding_transcript_exon_variant 1.0
rrl 1473834 n.178_179insTAG non_coding_transcript_exon_variant 0.89
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 1.0
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 1.0
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 1.0
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.86
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0
rrl 1473922 n.265A>T non_coding_transcript_exon_variant 1.0
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 1.0
rrl 1473933 n.276_277insAT non_coding_transcript_exon_variant 1.0
rrl 1473936 n.281_282delGC non_coding_transcript_exon_variant 1.0
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 1.0
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0
rrl 1473968 n.311C>T non_coding_transcript_exon_variant 1.0
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 1.0
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 1.0
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 1.0
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 1.0
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 1.0
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 1.0
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.98
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.93
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.82
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.6
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.82
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.9
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 1.0
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 1.0
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474387 n.730C>G non_coding_transcript_exon_variant 1.0
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.75
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.8
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.92
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.96
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.97
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 1.0
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 1.0
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 1.0
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.98
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 1.0
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 1.0
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 1.0
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 1.0
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.96
rrl 1474675 n.1018C>A non_coding_transcript_exon_variant 1.0
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 1.0
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 1.0
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 1.0
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 1.0
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 1.0
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 1.0
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 1.0
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 1.0
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 1.0
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 1.0
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 1.0
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.97
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.98
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.98
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.98
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.95
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 1.0
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.93
rrl 1474935 n.1278A>G non_coding_transcript_exon_variant 1.0
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 1.0
rrl 1475084 n.1427G>T non_coding_transcript_exon_variant 1.0
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 1.0
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 1.0
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 1.0
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 1.0
rrl 1475488 n.1831G>C non_coding_transcript_exon_variant 1.0
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 1.0
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 1.0
rrl 1475536 n.1879C>A non_coding_transcript_exon_variant 1.0
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 1.0
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 1.0
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 1.0
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 1.0
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 1.0
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 1.0
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 1.0
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 1.0
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.97
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.97
rrl 1475747 n.2090A>C non_coding_transcript_exon_variant 0.91
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.89
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.89
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.89
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 1.0
rrl 1475781 n.2124T>G non_coding_transcript_exon_variant 0.93
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 1.0
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 1.0
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 1.0
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.96
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.95
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.95
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.95
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.94
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 1.0
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.93
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.93
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.75
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 1.0
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.96
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.96
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 1.0
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.93
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.97
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 1.0
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 1.0
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 1.0
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.97
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.97
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.98
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.98
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.96
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.94
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.92
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.92
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.85
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.92
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.92
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.92
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.92
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 1.0
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.94
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.94
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.94
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 1.0
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 1.0
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 1.0
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 1.0
rrl 1476630 n.2973A>T non_coding_transcript_exon_variant 1.0
rpsA 1833685 c.144G>C synonymous_variant 1.0
rpsA 1833694 c.153G>C synonymous_variant 1.0
rpsA 1833704 p.Ile55Val missense_variant 1.0
rpsA 1833709 c.168C>G synonymous_variant 1.0
rpsA 1833721 c.180A>G synonymous_variant 1.0
rpsA 1833724 c.183C>T synonymous_variant 1.0
rpsA 1833727 c.186G>C synonymous_variant 1.0
rpsA 1833734 p.Ala65Ser missense_variant 1.0
rpsA 1833739 c.198C>T synonymous_variant 1.0
rpsA 1833742 c.201A>G synonymous_variant 1.0
rpsA 1833745 c.204G>T synonymous_variant 1.0
rpsA 1833771 p.Asn77Ser missense_variant 1.0
rpsA 1834030 c.489C>G synonymous_variant 1.0
rpsA 1834034 p.Ile165Leu missense_variant 0.86
rpsA 1834040 p.Lys167Gln missense_variant 0.86
rpsA 1834046 p.Ile169Leu missense_variant 0.86
rpsA 1834054 c.513C>G synonymous_variant 1.0
rpsA 1834061 p.Ile174Leu missense_variant 0.89
rpsA 1834069 c.528G>C synonymous_variant 1.0
rpsA 1834093 c.552G>C synonymous_variant 1.0
rpsA 1834099 c.558C>G synonymous_variant 1.0
rpsA 1834108 c.567C>G synonymous_variant 1.0
rpsA 1834109 p.Trp190Leu missense_variant 1.0
rpsA 1834114 c.573G>C synonymous_variant 1.0
rpsA 1834129 c.588C>G synonymous_variant 1.0
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834187 p.Val216Ile missense_variant 0.89
rpsA 1834210 c.669C>T synonymous_variant 1.0
rpsA 1834222 c.681T>C synonymous_variant 1.0
rpsA 1834225 c.684C>G synonymous_variant 1.0
rpsA 1834231 c.690T>C synonymous_variant 1.0
rpsA 1834240 c.699T>C synonymous_variant 1.0
rpsA 1834243 c.702G>C synonymous_variant 1.0
rpsA 1834249 c.708T>C synonymous_variant 1.0
rpsA 1834261 c.720A>C synonymous_variant 1.0
rpsA 1834279 p.Asp246Glu missense_variant 1.0
rpsA 1834331 p.Asp264Ser missense_variant 1.0
rpsA 1834339 p.Asp266Glu missense_variant 1.0
rpsA 1834340 p.Met267Leu missense_variant 1.0
rpsA 1834348 c.807T>C synonymous_variant 1.0
rpsA 1834354 c.813G>C synonymous_variant 1.0
rpsA 1834357 c.816T>C synonymous_variant 1.0
rpsA 1834361 c.820_822delTTGinsCTC synonymous_variant 1.0
rpsA 1834366 c.825A>G synonymous_variant 1.0
rpsA 1834378 c.837T>G synonymous_variant 1.0
rpsA 1834395 p.Arg285Gln missense_variant 1.0
rpsA 1834397 p.His286Val missense_variant 1.0
rpsA 1834411 c.870T>C synonymous_variant 1.0
rpsA 1834423 c.882G>T synonymous_variant 1.0
rpsA 1834427 p.Ile296Val missense_variant 0.93
rpsA 1834431 p.Val297Ala missense_variant 0.93
rpsA 1834447 c.906C>G synonymous_variant 0.93
rpsA 1834451 c.910T>C synonymous_variant 1.0
rpsA 1834468 c.927A>G synonymous_variant 1.0
rpsA 1834482 p.Glu314Ala missense_variant 0.9
rpsA 1834486 p.Glu315Asp missense_variant 0.9
rpsA 1834489 c.948T>C synonymous_variant 1.0
rpsA 1834501 c.960G>C synonymous_variant 1.0
rpoA 3877935 p.Lys191Arg missense_variant 1.0
rpoA 3877938 c.570C>T synonymous_variant 1.0
rpoA 3878270 p.Leu80Ile missense_variant 0.75
rpoA 3878271 c.237T>C synonymous_variant 1.0
rpoA 3878274 c.234G>C synonymous_variant 0.75
rpoA 3878295 c.213A>G synonymous_variant 1.0
rpoA 3878298 c.210A>G synonymous_variant 1.0
rpoA 3878304 c.204G>C synonymous_variant 1.0
rpoA 3878313 c.195G>C synonymous_variant 1.0
rpoA 3878316 p.Thr64Ser missense_variant 1.0
rpoA 3878322 c.186A>G synonymous_variant 1.0
rpoA 3878331 c.177A>G synonymous_variant 1.0
rpoA 3878334 c.174T>C synonymous_variant 1.0
rpoA 3878337 c.171T>C synonymous_variant 1.0
rpoA 3878346 c.162T>C synonymous_variant 1.0
rpoA 3878352 c.156C>G synonymous_variant 1.0
clpC1 4038794 p.Ser637Thr missense_variant 1.0
clpC1 4038878 c.1827A>G synonymous_variant 1.0
clpC1 4038953 c.1752A>G synonymous_variant 1.0
clpC1 4038956 c.1749T>C synonymous_variant 1.0
clpC1 4038965 c.1740T>C synonymous_variant 1.0
clpC1 4038971 c.1734T>C synonymous_variant 1.0
clpC1 4038974 c.1731T>C synonymous_variant 1.0
clpC1 4038986 p.Asp573Glu missense_variant 1.0
clpC1 4038989 c.1716T>C synonymous_variant 1.0
clpC1 4038997 c.1708T>C synonymous_variant 1.0
clpC1 4039004 c.1701C>G synonymous_variant 1.0
clpC1 4039016 c.1689C>G synonymous_variant 1.0
clpC1 4039526 c.1179G>C synonymous_variant 1.0
clpC1 4039533 p.Asn391Ser missense_variant 1.0
clpC1 4039550 c.1155G>C synonymous_variant 1.0
clpC1 4039554 p.Thr384Asn missense_variant 1.0
clpC1 4039559 c.1146C>G synonymous_variant 1.0
clpC1 4039565 c.1140G>C synonymous_variant 1.0
clpC1 4039568 p.Met379Ile missense_variant 1.0
clpC1 4039574 p.Ala377Gly missense_variant 1.0
clpC1 4039577 c.1128T>C synonymous_variant 1.0
clpC1 4039586 c.1119G>C synonymous_variant 1.0
clpC1 4039593 p.Arg371Lys missense_variant 1.0
clpC1 4039610 c.1095G>C synonymous_variant 0.83
clpC1 4039616 c.1089G>C synonymous_variant 1.0
clpC1 4039628 c.1077C>G synonymous_variant 0.5
clpC1 4039642 p.Thr355Ala missense_variant 1.0
clpC1 4039649 c.1056G>C synonymous_variant 1.0
clpC1 4039652 p.Thr351Ser missense_variant 1.0
clpC1 4039661 c.1044T>C synonymous_variant 1.0
clpC1 4039670 c.1035G>C synonymous_variant 1.0
clpC1 4039673 c.1032G>C synonymous_variant 1.0
clpC1 4039694 c.1011G>C synonymous_variant 1.0
clpC1 4039711 p.Ile332Phe missense_variant 0.67
clpC1 4039714 p.Tyr331His missense_variant 1.0
clpC1 4039724 c.981A>G synonymous_variant 1.0
clpC1 4039736 c.969C>G synonymous_variant 1.0
clpC1 4039739 c.966C>G synonymous_variant 1.0
clpC1 4039748 c.957G>C synonymous_variant 1.0
clpC1 4039751 c.954A>G synonymous_variant 1.0
clpC1 4039757 c.948A>G synonymous_variant 1.0
clpC1 4039760 c.945T>C synonymous_variant 1.0
clpC1 4039766 c.939T>C synonymous_variant 1.0
clpC1 4039773 p.Lys311Leu missense_variant 1.0
clpC1 4039778 c.927A>G synonymous_variant 1.0
clpC1 4039793 c.912C>G synonymous_variant 1.0
clpC1 4039802 c.903G>C synonymous_variant 1.0
clpC1 4039898 c.807C>G synonymous_variant 1.0
clpC1 4039904 c.801A>G synonymous_variant 1.0
clpC1 4039916 c.789T>C synonymous_variant 1.0
clpC1 4039931 c.774T>C synonymous_variant 1.0
clpC1 4039937 p.Val256Ile missense_variant 1.0
clpC1 4039940 c.765G>C synonymous_variant 1.0
clpC1 4039946 c.759A>C synonymous_variant 1.0
clpC1 4039949 c.756G>C synonymous_variant 1.0
clpC1 4039952 c.753T>C synonymous_variant 1.0
clpC1 4039955 c.750G>C synonymous_variant 1.0
clpC1 4039960 p.Thr249Ser missense_variant 1.0
clpC1 4039979 c.726C>G synonymous_variant 1.0
clpC1 4040000 p.His235Lys missense_variant 1.0
clpC1 4040003 c.702G>C synonymous_variant 1.0
clpC1 4040009 c.696C>G synonymous_variant 1.0
clpC1 4040018 c.687G>C synonymous_variant 1.0
clpC1 4040021 c.684A>C synonymous_variant 1.0
clpC1 4040024 c.681A>G synonymous_variant 1.0
clpC1 4040033 c.672G>C synonymous_variant 1.0
clpC1 4040063 c.642G>C synonymous_variant 1.0
clpC1 4040066 c.639G>C synonymous_variant 1.0
clpC1 4040069 c.636G>C synonymous_variant 1.0
clpC1 4040083 p.Thr208Ser missense_variant 1.0
clpC1 4040087 c.618G>C synonymous_variant 1.0
clpC1 4040090 c.615T>C synonymous_variant 1.0
clpC1 4040096 p.Val203Ile missense_variant 1.0
clpC1 4040117 c.588A>G synonymous_variant 1.0
clpC1 4040129 c.576C>G synonymous_variant 1.0
clpC1 4040135 c.570C>G synonymous_variant 1.0
clpC1 4040144 c.561G>C synonymous_variant 1.0
clpC1 4040147 c.558A>G synonymous_variant 1.0
clpC1 4040153 c.552A>G synonymous_variant 1.0
clpC1 4040156 p.Met183Arg missense_variant 1.0
clpC1 4040159 c.546G>T synonymous_variant 1.0
clpC1 4040162 c.543G>C synonymous_variant 1.0
clpC1 4040166 p.Ala180Gln missense_variant 1.0
clpC1 4040195 c.510G>C synonymous_variant 1.0
clpC1 4040267 c.438A>G synonymous_variant 1.0
clpC1 4040273 c.432T>C synonymous_variant 1.0
clpC1 4040282 c.423G>C synonymous_variant 1.0
clpC1 4040291 c.414G>C synonymous_variant 1.0
clpC1 4040306 c.399G>C synonymous_variant 1.0
clpC1 4040310 p.Thr132Asn missense_variant 1.0
clpC1 4040312 c.393G>C synonymous_variant 1.0
clpC1 4040315 p.Glu130Asp missense_variant 1.0
clpC1 4040330 c.375C>G synonymous_variant 1.0
clpC1 4040333 c.372G>C synonymous_variant 1.0
clpC1 4040348 c.357G>C synonymous_variant 1.0
clpC1 4040354 c.351A>G synonymous_variant 1.0
clpC1 4040357 c.348T>C synonymous_variant 1.0
clpC1 4040363 c.342A>C synonymous_variant 1.0
clpC1 4040606 c.99T>C synonymous_variant 1.0
clpC1 4040636 c.69C>G synonymous_variant 1.0
clpC1 4040643 p.Arg21Lys missense_variant 1.0
clpC1 4040654 c.51G>A synonymous_variant 1.0
clpC1 4040657 c.48T>C synonymous_variant 1.0
clpC1 4040672 c.31_33delAGGinsCGT synonymous_variant 1.0
clpC1 4040681 c.24T>C synonymous_variant 1.0
clpC1 4040690 c.15T>C synonymous_variant 1.0
clpC1 4040695 c.10C>A synonymous_variant 1.0
clpC1 4040696 c.9A>G synonymous_variant 1.0