TB-Profiler result

Run: ERR2229198
Summary

Run ID: ERR2229198

Sample name:

Date: 2024-03-26T20:15:54.326387

Number of reads: 731987

Percentage reads mapped: 35.37

Median coverage: 17.0

Strain: lineage4.8

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.8 Euro-American (mainly T) RD219 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rpoB 760982 c.1176G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.42 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761322 p.Ile506Val missense_variant 0.26 rifampicin Uncertain significance
rpoB 761327 c.1521A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.29 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 762938 c.-432G>C upstream_gene_variant 0.29 rifampicin
rpoC 763453 c.84C>G synonymous_variant 0.34 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 763480 c.111C>G synonymous_variant 0.48 rifampicin
rpoC 763483 c.114G>C synonymous_variant 0.5 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763504 c.135C>G synonymous_variant 0.49 rifampicin
rpoC 763507 c.138G>C synonymous_variant 0.51 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.45 rifampicin
rpoC 763534 c.165T>C synonymous_variant 0.47 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.47 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 0.31 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCC frameshift_variant&missense_variant 0.26 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.27 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.27 rifampicin
rpoC 764449 c.1080G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764452 c.1083T>C synonymous_variant 0.27 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.58 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.45 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.45 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764677 c.1308C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 0.24 rifampicin
rpoC 764706 p.Leu446Gln missense_variant 0.28 rifampicin Uncertain significance
rpoC 764737 c.1368G>C synonymous_variant 0.2 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781796 p.Met79Ile missense_variant 0.29 streptomycin
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471914 n.69A>G non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471943 n.98T>C non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471967 n.122G>A non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471980 n.135G>T non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1471981 n.136C>G non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.57 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.57 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471997 n.152T>C non_coding_transcript_exon_variant 0.56 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.32 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.3 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.34 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.57 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472133 n.288G>A non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_461delGTCCGGGTT non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472309 n.464C>A non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472310 n.465T>A non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472312 n.468_470delGAT non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472446 n.601T>G non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472466 n.621C>T non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472467 n.622G>C non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472492 n.648_651delTACT non_coding_transcript_exon_variant 0.51 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472498 n.656_657insTAGG non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472507 n.662C>A non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472517 n.672T>C non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472545 n.700A>G non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472583 n.738T>G non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472675 n.832delC non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.58 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.6 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472791 n.946G>T non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472793 n.948A>C non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472803 n.958T>C non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472996 n.1151T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473062 n.1217T>G non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473065 n.1220C>A non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.84 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473289 n.1444T>G non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473291 n.1446_1449delGGGAinsAATGGG non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473679 n.22_23insAC non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1473722 n.65G>C non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474229 n.572A>G non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474235 n.578_579insT non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1474242 n.585delAinsTC non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474286 n.629C>G non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1474476 n.819C>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>C non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.83 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474948 n.1291C>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475028 n.1371G>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404_1408delCAAGGinsGTCA non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475068 n.1411A>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475078 n.1421T>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475082 n.1425C>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475542 n.1885A>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475571 n.1914A>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475586 n.1929C>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475706 n.2049A>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475735 n.2078T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475740 n.2083G>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475757 n.2100_2101insG non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475769 n.2112_2113insC non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475782 n.2125T>C non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475788 n.2131C>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1475791 n.2134A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475983 n.2326T>C non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.56 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475996 n.2339T>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476000 n.2343G>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>C non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476060 n.2403T>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1476085 n.2428G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476088 n.2431A>G non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476095 n.2439delT non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476099 n.2442A>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476103 n.2446_2447insG non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476115 n.2458T>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.66 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.55 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476268 n.2611A>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476275 n.2618T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476325 n.2668A>C non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.8 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476491 n.2834T>C non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.72 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476524 n.2867delCinsAGG non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1476529 n.2872A>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476531 n.2874T>G non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476537 n.2880_2883delAAACinsGT non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.76 capreomycin
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.73 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833727 c.186G>C synonymous_variant 0.32 pyrazinamide
rpsA 1833734 c.193_195delGCCinsTG frameshift_variant&missense_variant 0.35 pyrazinamide Uncertain significance
rpsA 1833742 c.201A>G synonymous_variant 0.38 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.33 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.35 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.36 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.33 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.36 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.32 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.31 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.38 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.39 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834307 c.766_768delGACinsCG frameshift_variant&missense_variant 0.38 pyrazinamide Uncertain significance
rpsA 1834318 c.777C>G synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
rpsA 1834327 c.786G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834330 c.789C>G synonymous_variant 0.42 pyrazinamide
rpsA 1834345 p.Asp268Glu missense_variant 0.34 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.32 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.31 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 0.31 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.31 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
rpsA 1834395 p.Arg285Gln missense_variant 0.52 pyrazinamide
rpsA 1834399 p.His286Gln missense_variant 0.5 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.33 pyrazinamide
rpsA 1834415 p.Ala292Gln missense_variant 0.33 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.33 pyrazinamide
rpsA 1834427 p.Ile296Val missense_variant 0.32 pyrazinamide Uncertain significance
rpsA 1834439 p.Lys300Arg missense_variant 0.33 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.3 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
PPE35 2168728 p.Gly629Arg missense_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
clpC1 4038755 p.Gly650Ala missense_variant 0.38 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.36 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.36 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.32 pyrazinamide
clpC1 4038782 c.1921_1923delGTGinsAC frameshift_variant&missense_variant 0.32 pyrazinamide
clpC1 4038801 p.Tyr635Phe missense_variant 0.42 pyrazinamide
clpC1 4038806 p.Glu633Asp missense_variant 0.37 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.37 pyrazinamide
clpC1 4038830 c.1875C>T synonymous_variant 0.33 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 0.33 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
clpC1 4038896 c.1809C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039838 c.867G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039868 c.837C>G synonymous_variant 0.28 pyrazinamide
clpC1 4039875 p.Asn277Arg missense_variant 0.33 pyrazinamide
clpC1 4039886 c.819C>G synonymous_variant 0.44 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.43 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 0.42 pyrazinamide
clpC1 4039919 c.786C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.3 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.39 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.39 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.51 pyrazinamide
clpC1 4040000 c.703_705delCACinsAG frameshift_variant&missense_variant 0.38 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.37 pyrazinamide
clpC1 4040009 p.Ala232Lys missense_variant 0.37 pyrazinamide
clpC1 4040021 c.684A>G synonymous_variant 0.52 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.52 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 0.52 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.52 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>T synonymous_variant 0.5 pyrazinamide
clpC1 4040060 c.643_645delATCinsGG frameshift_variant&missense_variant 0.48 pyrazinamide
clpC1 4040066 c.639G>C synonymous_variant 0.5 pyrazinamide
clpC1 4040072 c.633C>T synonymous_variant 0.49 pyrazinamide
clpC1 4040084 c.621C>T synonymous_variant 0.47 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.47 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4040093 c.610_612delCTCinsTG frameshift_variant&synonymous_variant 0.47 pyrazinamide
clpC1 4040117 c.588A>G synonymous_variant 0.52 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.29 pyrazinamide
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R