TB-Profiler result

Run: ERR2229198
Summary

Run ID: ERR2229198

Sample name:

Date: 31-03-2023 16:48:25

Number of reads: 731987

Percentage reads mapped: 35.37

Strain: lineage4.8

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761116 p.Asn437Thr missense_variant 0.17 rifampicin
katG 2155102 p.Tyr337Phe missense_variant 0.19 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6666 c.1429delG frameshift_variant 0.13
gyrB 7139 p.Arg634Cys missense_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9287 c.1986G>A synonymous_variant 0.17
gyrA 9505 p.Thr735Ile missense_variant 0.13
mshA 576108 p.Ala254Gly missense_variant 0.36
ccsA 620309 p.Phe140Tyr missense_variant 0.17
ccsA 620598 c.708C>T synonymous_variant 0.18
rpoB 760461 p.Arg219Cys missense_variant 0.13
rpoB 760916 c.1110C>G synonymous_variant 0.29
rpoB 760925 c.1119T>C synonymous_variant 0.38
rpoB 760946 c.1140A>G synonymous_variant 0.31
rpoB 760953 p.Ile383Val missense_variant 0.31
rpoB 760959 p.Val385Leu missense_variant 0.31
rpoB 760965 p.Met387Leu missense_variant 0.33
rpoB 760968 p.Ser388Ala missense_variant 0.33
rpoB 760973 c.1167G>C synonymous_variant 0.33
rpoB 760982 c.1176G>C synonymous_variant 0.44
rpoB 760985 c.1179G>C synonymous_variant 0.47
rpoB 760991 c.1185G>C synonymous_variant 0.42
rpoB 761015 c.1209G>C synonymous_variant 0.27
rpoB 761027 c.1221A>G synonymous_variant 0.28
rpoB 761036 c.1230G>C synonymous_variant 0.28
rpoB 761037 c.1231T>C synonymous_variant 0.28
rpoB 761057 c.1251G>C synonymous_variant 0.24
rpoB 761060 c.1254C>G synonymous_variant 0.24
rpoB 761064 p.Ala420Ser missense_variant 0.25
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.17
rpoB 761102 c.1296A>G synonymous_variant 0.17
rpoB 761196 c.1390_1391insA frameshift_variant 0.25
rpoB 761213 c.1407G>C synonymous_variant 0.38
rpoB 761249 c.1443A>G synonymous_variant 0.23
rpoB 761252 c.1446C>G synonymous_variant 0.2
rpoB 761255 c.1449T>G synonymous_variant 0.2
rpoB 761258 c.1452G>A synonymous_variant 0.19
rpoB 761261 c.1455G>C synonymous_variant 0.17
rpoB 761264 c.1458C>G synonymous_variant 0.17
rpoB 761273 c.1467T>C synonymous_variant 0.17
rpoB 761288 c.1482G>C synonymous_variant 0.15
rpoB 761289 p.Ser495Ala missense_variant 0.15
rpoB 761293 p.Val496Ala missense_variant 0.16
rpoB 761296 p.Tyr497Phe missense_variant 0.15
rpoB 761299 p.Ala498Gly missense_variant 0.15
rpoB 761322 p.Ile506Val missense_variant 0.26
rpoB 761327 c.1521A>G synonymous_variant 0.29
rpoB 761570 c.1764T>C synonymous_variant 0.14
rpoB 761573 c.1767C>G synonymous_variant 0.14
rpoB 761600 c.1794T>C synonymous_variant 0.15
rpoB 761603 c.1797C>G synonymous_variant 0.14
rpoB 761606 c.1800C>G synonymous_variant 0.18
rpoB 761612 c.1806G>C synonymous_variant 0.17
rpoB 761613 p.Ala603Ser missense_variant 0.17
rpoB 761631 p.Ala609Ser missense_variant 0.17
rpoB 761636 c.1830G>C synonymous_variant 0.17
rpoB 761643 p.Val613Leu missense_variant 0.17
rpoB 761648 c.1842T>C synonymous_variant 0.17
rpoB 761657 c.1851C>G synonymous_variant 0.17
rpoB 761666 c.1860G>C synonymous_variant 0.15
rpoB 761999 c.2193G>C synonymous_variant 0.14
rpoB 762000 c.2194_2195delTCinsAG synonymous_variant 0.14
rpoB 762003 p.Asn733His missense_variant 0.13
rpoB 762014 c.2208C>G synonymous_variant 0.12
rpoB 762015 p.Glu737Gln missense_variant 0.12
rpoB 762020 p.Glu738Asp missense_variant 0.12
rpoB 762053 c.2247T>C synonymous_variant 0.13
rpoB 762057 p.Ile751Val missense_variant 0.13
rpoB 762062 c.2256T>C synonymous_variant 0.13
rpoB 762065 c.2259T>C synonymous_variant 0.13
rpoB 762086 c.2280G>C synonymous_variant 0.13
rpoB 762101 c.2295C>G synonymous_variant 0.19
rpoB 762122 p.Asp772Glu missense_variant 0.18
rpoB 762128 c.2322G>C synonymous_variant 0.2
rpoB 762140 c.2334G>C synonymous_variant 0.25
rpoB 762143 c.2337T>C synonymous_variant 0.24
rpoB 762149 c.2343G>C synonymous_variant 0.3
rpoB 762156 p.Val784Ile missense_variant 0.33
rpoB 762167 c.2361T>C synonymous_variant 0.28
rpoB 762173 p.Glu789Asp missense_variant 0.28
rpoB 762175 c.2369_2370insCG frameshift_variant 0.27
rpoB 762178 p.Arg791Pro missense_variant 0.27
rpoB 762179 c.2374_2375delGA frameshift_variant 0.27
rpoB 762185 c.2379G>C synonymous_variant 0.29
rpoB 762218 c.2412T>C synonymous_variant 0.29
rpoB 762230 c.2424G>C synonymous_variant 0.21
rpoB 762233 c.2427G>C synonymous_variant 0.22
rpoB 762236 c.2430G>C synonymous_variant 0.23
rpoB 762251 c.2445G>C synonymous_variant 0.12
rpoC 762395 c.-975G>C upstream_gene_variant 0.33
rpoC 762398 c.-972T>G upstream_gene_variant 0.33
rpoC 762404 c.-966T>C upstream_gene_variant 0.18
rpoC 762407 c.-963G>C upstream_gene_variant 0.25
rpoC 762410 c.-960T>G upstream_gene_variant 0.25
rpoC 762416 c.-954A>G upstream_gene_variant 0.25
rpoB 762426 p.Ser874Thr missense_variant 0.4
rpoC 762443 c.-927G>C upstream_gene_variant 0.22
rpoC 762470 c.-900G>C upstream_gene_variant 0.25
rpoB 762474 p.Gly890Ser missense_variant 0.25
rpoB 762480 p.Ile892Val missense_variant 0.25
rpoC 762485 c.-885G>C upstream_gene_variant 0.25
rpoC 762491 c.-879T>C upstream_gene_variant 0.22
rpoC 762899 c.-471G>C upstream_gene_variant 0.13
rpoC 762917 c.-453C>G upstream_gene_variant 0.18
rpoC 762923 c.-447C>G upstream_gene_variant 0.24
rpoC 762929 c.-441G>C upstream_gene_variant 0.23
rpoC 762938 c.-432G>C upstream_gene_variant 0.29
rpoC 762959 c.-411G>C upstream_gene_variant 0.21
rpoC 762971 c.-399G>C upstream_gene_variant 0.15
rpoC 762980 c.-390T>C upstream_gene_variant 0.17
rpoC 762989 c.-381G>C upstream_gene_variant 0.19
rpoC 762995 c.-375G>T upstream_gene_variant 0.21
rpoB 763005 p.Cys1067Gly missense_variant 0.21
rpoC 763022 c.-348C>G upstream_gene_variant 0.13
rpoC 763028 c.-342T>C upstream_gene_variant 0.15
rpoC 763031 c.-339T>C upstream_gene_variant 0.15
rpoB 763038 p.Thr1078Ala missense_variant 0.27
rpoC 763043 c.-327G>C upstream_gene_variant 0.5
rpoC 763053 c.-317T>C upstream_gene_variant 0.57
rpoC 763070 c.-300T>C upstream_gene_variant 0.33
rpoC 763444 c.75T>C synonymous_variant 0.15
rpoC 763453 c.84C>G synonymous_variant 0.34
rpoC 763456 c.87A>G synonymous_variant 0.37
rpoC 763480 c.111C>G synonymous_variant 0.48
rpoC 763483 c.114G>C synonymous_variant 0.5
rpoC 763486 c.117T>C synonymous_variant 0.48
rpoC 763504 c.135C>G synonymous_variant 0.49
rpoC 763507 c.138G>C synonymous_variant 0.51
rpoC 763528 c.159G>C synonymous_variant 0.45
rpoC 763534 c.165T>C synonymous_variant 0.47
rpoC 763537 c.168C>G synonymous_variant 0.47
rpoC 763546 c.177A>G synonymous_variant 0.54
rpoC 763570 c.201G>C synonymous_variant 0.39
rpoC 763573 c.204G>C synonymous_variant 0.39
rpoC 763594 c.225C>T synonymous_variant 0.46
rpoC 763633 c.264T>C synonymous_variant 0.45
rpoC 763660 c.291T>G synonymous_variant 0.5
rpoC 763669 c.300C>G synonymous_variant 0.48
rpoC 763675 c.306C>G synonymous_variant 0.5
rpoC 763696 c.327T>C synonymous_variant 0.36
rpoC 763702 c.333C>G synonymous_variant 0.31
rpoC 763705 c.336G>C synonymous_variant 0.31
rpoC 763708 c.339G>C synonymous_variant 0.32
rpoC 763711 c.342G>C synonymous_variant 0.32
rpoC 763714 c.345G>C synonymous_variant 0.32
rpoC 763717 c.348T>C synonymous_variant 0.33
rpoC 763741 c.372C>T synonymous_variant 0.23
rpoC 763744 c.375G>C synonymous_variant 0.23
rpoC 763765 c.396T>G synonymous_variant 0.25
rpoC 763772 p.Val135Met missense_variant 0.12
rpoC 764215 c.846A>C synonymous_variant 0.14
rpoC 764217 p.Asn283Thr missense_variant 0.14
rpoC 764227 c.858G>C synonymous_variant 0.12
rpoC 764338 p.Glu323Asp missense_variant 0.15
rpoC 764347 c.978G>C synonymous_variant 0.5
rpoC 764387 c.1018T>C synonymous_variant 0.47
rpoC 764405 c.1036A>C synonymous_variant 0.34
rpoC 764410 c.1041G>C synonymous_variant 0.31
rpoC 764431 c.1062G>C synonymous_variant 0.26
rpoC 764434 c.1065A>G synonymous_variant 0.26
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.26
rpoC 764441 p.Ile358Leu missense_variant 0.27
rpoC 764446 c.1077T>C synonymous_variant 0.27
rpoC 764449 c.1080G>T synonymous_variant 0.27
rpoC 764452 c.1083T>C synonymous_variant 0.27
rpoC 764458 c.1089G>C synonymous_variant 0.31
rpoC 764461 c.1092A>G synonymous_variant 0.31
rpoC 764497 c.1128A>G synonymous_variant 0.22
rpoC 764498 p.Ser377Ala missense_variant 0.24
rpoC 764503 c.1134G>C synonymous_variant 0.33
rpoC 764521 c.1152T>C synonymous_variant 0.46
rpoC 764536 c.1167G>C synonymous_variant 0.58
rpoC 764539 c.1170C>G synonymous_variant 0.61
rpoC 764566 c.1197C>G synonymous_variant 0.61
rpoC 764575 c.1206T>G synonymous_variant 0.55
rpoC 764581 c.1212T>C synonymous_variant 0.45
rpoC 764582 p.Leu405Met missense_variant 0.45
rpoC 764623 c.1254C>G synonymous_variant 0.34
rpoC 764632 c.1263T>C synonymous_variant 0.26
rpoC 764644 c.1275G>C synonymous_variant 0.36
rpoC 764650 c.1281G>T synonymous_variant 0.4
rpoC 764662 c.1293G>C synonymous_variant 0.33
rpoC 764677 c.1308C>G synonymous_variant 0.29
rpoC 764695 c.1326T>C synonymous_variant 0.24
rpoC 764706 p.Leu446Gln missense_variant 0.28
rpoC 764737 c.1368G>C synonymous_variant 0.2
rpoC 764764 c.1395T>C synonymous_variant 0.21
rpoC 764830 c.1461C>G synonymous_variant 0.17
rpoC 764843 p.Ala492Thr missense_variant 0.21
rpoC 765551 p.Gly728Arg missense_variant 0.17
rpoC 767044 c.3675G>C synonymous_variant 0.29
rpoC 767056 c.3687C>G synonymous_variant 0.29
rpoC 767059 c.3690T>C synonymous_variant 0.25
rpoC 767062 c.3693C>G synonymous_variant 0.25
rpoC 767068 c.3699G>C synonymous_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776730 p.Tyr584Phe missense_variant 0.33
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781796 p.Met79Ile missense_variant 0.29
rpsL 781802 c.243G>C synonymous_variant 0.24
rplC 800648 c.-161A>G upstream_gene_variant 0.27
rplC 800654 c.-155T>C upstream_gene_variant 0.27
rplC 800667 c.-142_-141delTCinsAG upstream_gene_variant 0.14
fbiC 1303464 c.534A>G synonymous_variant 0.2
fbiC 1303470 c.540T>C synonymous_variant 0.2
fbiC 1303480 p.Gln184Glu missense_variant 0.2
fbiC 1303747 p.Thr273Ala missense_variant 1.0
Rv1258c 1406448 p.Leu298Pro missense_variant 0.29
embR 1416578 p.Gln257Arg missense_variant 0.14
atpE 1461228 p.Ala62Thr missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471914 n.69A>G non_coding_transcript_exon_variant 0.71
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.69
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.71
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.67
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.67
rrs 1471943 n.98T>C non_coding_transcript_exon_variant 0.68
rrs 1471967 n.122G>A non_coding_transcript_exon_variant 0.53
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.53
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.52
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.53
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.55
rrs 1471980 n.135G>T non_coding_transcript_exon_variant 0.55
rrs 1471981 n.136C>G non_coding_transcript_exon_variant 0.55
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.57
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.57
rrs 1471997 n.152T>C non_coding_transcript_exon_variant 0.56
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.32
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.3
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.34
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.57
rrs 1472133 n.288G>A non_coding_transcript_exon_variant 0.71
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.76
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.76
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.75
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.78
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.82
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.76
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.76
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.67
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.61
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.59
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.59
rrs 1472297 n.453_461delGTCCGGGTT non_coding_transcript_exon_variant 0.54
rrs 1472309 n.464C>A non_coding_transcript_exon_variant 0.53
rrs 1472310 n.465T>A non_coding_transcript_exon_variant 0.52
rrs 1472312 n.468_470delGAT non_coding_transcript_exon_variant 0.53
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.58
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.58
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.58
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.72
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.71
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.71
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.72
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.79
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.75
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.7
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.7
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.7
rrs 1472446 n.601T>G non_coding_transcript_exon_variant 0.7
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.7
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.71
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.7
rrs 1472466 n.621C>T non_coding_transcript_exon_variant 0.68
rrs 1472467 n.622G>C non_coding_transcript_exon_variant 0.68
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.68
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.69
rrs 1472492 n.648_651delTACT non_coding_transcript_exon_variant 0.51
rrs 1472498 n.656_657insTAGG non_coding_transcript_exon_variant 0.54
rrs 1472507 n.662C>A non_coding_transcript_exon_variant 0.66
rrs 1472517 n.672T>C non_coding_transcript_exon_variant 0.72
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.75
rrs 1472545 n.700A>G non_coding_transcript_exon_variant 0.75
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 0.7
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.62
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 0.61
rrs 1472583 n.738T>G non_coding_transcript_exon_variant 0.61
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.61
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.72
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.69
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.69
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.65
rrs 1472675 n.832delC non_coding_transcript_exon_variant 0.61
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.59
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.59
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.58
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.59
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.65
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.61
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.6
rrs 1472791 n.946G>T non_coding_transcript_exon_variant 0.39
rrs 1472793 n.948A>C non_coding_transcript_exon_variant 0.38
rrs 1472803 n.958T>C non_coding_transcript_exon_variant 0.4
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.68
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.67
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.67
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.78
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.75
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.76
rrs 1472996 n.1151T>C non_coding_transcript_exon_variant 0.76
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.82
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.81
rrs 1473062 n.1217T>G non_coding_transcript_exon_variant 0.8
rrs 1473065 n.1220C>A non_coding_transcript_exon_variant 0.81
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.85
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.87
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.86
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.84
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.84
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.79
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.81
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.81
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.81
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.8
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.8
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.81
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.86
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.84
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.82
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 0.79
rrs 1473289 n.1444T>G non_coding_transcript_exon_variant 0.77
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.81
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.81
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.81
rrl 1473392 n.-266C>A upstream_gene_variant 0.36
rrl 1473679 n.22_23insAC non_coding_transcript_exon_variant 0.41
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.4
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.4
rrl 1473722 n.65G>C non_coding_transcript_exon_variant 0.36
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.19
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.21
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.33
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.26
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.26
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.35
rrl 1474229 n.572A>G non_coding_transcript_exon_variant 0.35
rrl 1474235 n.578_579insT non_coding_transcript_exon_variant 0.37
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.39
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.49
rrl 1474286 n.629C>G non_coding_transcript_exon_variant 0.3
rrl 1474309 n.652G>T non_coding_transcript_exon_variant 0.21
rrl 1474311 n.654G>C non_coding_transcript_exon_variant 0.23
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.51
rrl 1474476 n.819C>G non_coding_transcript_exon_variant 0.66
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.68
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.78
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.8
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.82
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.77
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.77
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.77
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.71
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.71
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.72
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.72
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.81
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.83
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.36
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.69
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.66
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.66
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.66
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.65
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.74
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.76
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.76
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.74
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.79
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.78
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.77
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.77
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.79
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.79
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.8
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.81
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.78
rrl 1474830 n.1173A>C non_coding_transcript_exon_variant 0.78
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.78
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.78
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.83
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.69
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.67
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.72
rrl 1474948 n.1291C>T non_coding_transcript_exon_variant 0.24
rrl 1475028 n.1371G>C non_coding_transcript_exon_variant 0.66
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 0.66
rrl 1475068 n.1411A>C non_coding_transcript_exon_variant 0.6
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.6
rrl 1475078 n.1421T>G non_coding_transcript_exon_variant 0.61
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.61
rrl 1475082 n.1425C>G non_coding_transcript_exon_variant 0.61
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.62
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.62
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 0.7
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.65
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.65
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.7
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.34
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.38
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.24
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.25
rrl 1475542 n.1885A>G non_coding_transcript_exon_variant 0.23
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.25
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.24
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.27
rrl 1475571 n.1914A>T non_coding_transcript_exon_variant 0.32
rrl 1475586 n.1929C>T non_coding_transcript_exon_variant 0.26
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.64
rrl 1475706 n.2049A>C non_coding_transcript_exon_variant 0.69
rrl 1475735 n.2078T>C non_coding_transcript_exon_variant 0.68
rrl 1475740 n.2083G>C non_coding_transcript_exon_variant 0.71
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.7
rrl 1475757 n.2100_2101insG non_coding_transcript_exon_variant 0.7
rrl 1475769 n.2112_2113insC non_coding_transcript_exon_variant 0.68
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.73
rrl 1475782 n.2125T>C non_coding_transcript_exon_variant 0.79
rrl 1475788 n.2131C>G non_coding_transcript_exon_variant 0.76
rrl 1475791 n.2134A>G non_coding_transcript_exon_variant 0.77
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.71
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.7
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.7
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.73
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.71
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.74
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.76
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.75
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.79
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.81
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.67
rrl 1475983 n.2326T>C non_coding_transcript_exon_variant 0.62
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.56
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.56
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.56
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.55
rrl 1475996 n.2339T>A non_coding_transcript_exon_variant 0.53
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.53
rrl 1476000 n.2343G>T non_coding_transcript_exon_variant 0.54
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.54
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.65
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.61
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.62
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.63
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.55
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.56
rrl 1476046 n.2389G>C non_coding_transcript_exon_variant 0.56
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.55
rrl 1476060 n.2403T>G non_coding_transcript_exon_variant 0.62
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.55
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.45
rrl 1476085 n.2428G>A non_coding_transcript_exon_variant 0.42
rrl 1476088 n.2431A>G non_coding_transcript_exon_variant 0.39
rrl 1476095 n.2439delT non_coding_transcript_exon_variant 0.33
rrl 1476099 n.2442A>C non_coding_transcript_exon_variant 0.33
rrl 1476103 n.2446_2447insG non_coding_transcript_exon_variant 0.32
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.32
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.3
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.26
rrl 1476115 n.2458T>G non_coding_transcript_exon_variant 0.26
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.26
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.58
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.61
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.66
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.65
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.65
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.64
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.64
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.61
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.56
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.56
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.56
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.56
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.55
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.54
rrl 1476268 n.2611A>G non_coding_transcript_exon_variant 0.54
rrl 1476275 n.2618T>C non_coding_transcript_exon_variant 0.52
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.52
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.52
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.53
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.6
rrl 1476298 n.2641C>A non_coding_transcript_exon_variant 0.61
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.62
rrl 1476309 n.2652G>T non_coding_transcript_exon_variant 0.69
rrl 1476325 n.2668A>C non_coding_transcript_exon_variant 0.74
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.8
rrl 1476491 n.2834T>C non_coding_transcript_exon_variant 0.73
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.72
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.68
rrl 1476529 n.2872A>T non_coding_transcript_exon_variant 0.64
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.64
rrl 1476531 n.2874T>G non_coding_transcript_exon_variant 0.65
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.76
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.73
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.73
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.66
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.66
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.65
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.65
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.68
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.4
fabG1 1673380 c.-60C>G upstream_gene_variant 0.25
fabG1 1673416 c.-24G>A upstream_gene_variant 0.14
fabG1 1673993 p.Tyr185Cys missense_variant 0.18
inhA 1674072 c.-130C>T upstream_gene_variant 0.13
fabG1 1674118 p.Glu227* stop_gained 0.14
rpsA 1833694 c.153G>C synonymous_variant 0.15
rpsA 1833721 c.180A>G synonymous_variant 0.21
rpsA 1833727 c.186G>C synonymous_variant 0.32
rpsA 1833734 p.Ala65Ser missense_variant 0.35
rpsA 1833742 c.201A>G synonymous_variant 0.38
rpsA 1833781 c.240T>C synonymous_variant 0.29
rpsA 1833782 p.Ser81Thr missense_variant 0.29
rpsA 1833790 c.249T>C synonymous_variant 0.42
rpsA 1833794 p.Glu85His missense_variant 0.42
rpsA 1833802 c.261A>G synonymous_variant 0.31
rpsA 1833808 c.267G>C synonymous_variant 0.26
rpsA 1833811 c.270G>C synonymous_variant 0.26
rpsA 1833815 p.Thr92Gln missense_variant 0.25
rpsA 1833829 c.288A>G synonymous_variant 0.33
rpsA 1833841 c.300C>G synonymous_variant 0.35
rpsA 1833847 c.306C>G synonymous_variant 0.36
rpsA 1833856 c.315A>G synonymous_variant 0.33
rpsA 1833862 c.321G>C synonymous_variant 0.36
rpsA 1833874 c.333T>C synonymous_variant 0.32
rpsA 1833886 c.345C>G synonymous_variant 0.23
rpsA 1833893 p.Ala118Lys missense_variant 0.19
rpsA 1833896 p.Leu119Ile missense_variant 0.2
rpsA 1833904 p.Glu121Asp missense_variant 0.19
rpsA 1833905 p.Lys122Glu missense_variant 0.2
rpsA 1833910 c.371_372delAG frameshift_variant 0.2
rpsA 1833915 c.374_375insAT frameshift_variant 0.2
rpsA 1833921 p.Lys127Thr missense_variant 0.22
rpsA 1833949 c.408T>C synonymous_variant 0.25
rpsA 1833955 c.414G>C synonymous_variant 0.22
rpsA 1833970 c.429G>C synonymous_variant 0.27
rpsA 1833979 c.438T>C synonymous_variant 0.21
rpsA 1833991 c.450C>G synonymous_variant 0.18
rpsA 1834000 c.459G>C synonymous_variant 0.29
rpsA 1834012 c.471G>C synonymous_variant 0.25
rpsA 1834015 c.474G>C synonymous_variant 0.25
rpsA 1834028 p.Pro163Thr missense_variant 0.14
rpsA 1834033 c.492C>T synonymous_variant 0.29
rpsA 1834034 p.Ile165Val missense_variant 0.29
rpsA 1834040 p.Lys167Arg missense_variant 0.14
rpsA 1834093 c.552G>C synonymous_variant 0.25
rpsA 1834102 c.561T>C synonymous_variant 0.18
rpsA 1834240 c.699T>C synonymous_variant 0.19
rpsA 1834249 c.708T>C synonymous_variant 0.31
rpsA 1834261 c.720A>G synonymous_variant 0.37
rpsA 1834264 c.723G>C synonymous_variant 0.38
rpsA 1834294 c.753G>C synonymous_variant 0.36
rpsA 1834298 p.Gln253Glu missense_variant 0.39
rpsA 1834303 c.762T>C synonymous_variant 0.4
rpsA 1834306 c.765T>C synonymous_variant 0.38
rpsA 1834307 p.Asp256Gln missense_variant 0.38
rpsA 1834318 c.777C>G synonymous_variant 0.41
rpsA 1834327 c.786G>C synonymous_variant 0.45
rpsA 1834330 c.789C>G synonymous_variant 0.42
rpsA 1834345 p.Asp268Glu missense_variant 0.34
rpsA 1834348 c.807T>C synonymous_variant 0.35
rpsA 1834354 c.813G>C synonymous_variant 0.32
rpsA 1834357 c.816T>C synonymous_variant 0.31
rpsA 1834360 c.819G>C synonymous_variant 0.31
rpsA 1834361 c.820T>C synonymous_variant 0.31
rpsA 1834366 c.825A>G synonymous_variant 0.37
rpsA 1834378 c.837T>C synonymous_variant 0.44
rpsA 1834395 p.Arg285Gln missense_variant 0.52
rpsA 1834399 p.His286Gln missense_variant 0.5
rpsA 1834411 c.870T>C synonymous_variant 0.33
rpsA 1834415 p.Ala292Gln missense_variant 0.33
rpsA 1834423 c.882G>C synonymous_variant 0.33
rpsA 1834427 p.Ile296Val missense_variant 0.32
rpsA 1834439 p.Lys300Arg missense_variant 0.33
rpsA 1834451 c.910T>C synonymous_variant 0.3
rpsA 1834456 c.915T>G synonymous_variant 0.26
rpsA 1834465 c.924T>C synonymous_variant 0.24
rpsA 1834468 c.927A>G synonymous_variant 0.24
rpsA 1834477 c.936C>G synonymous_variant 0.22
rpsA 1834489 c.948T>C synonymous_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918584 c.645A>G synonymous_variant 0.18
ndh 2102565 c.478C>A synonymous_variant 0.25
ndh 2103198 c.-156C>A upstream_gene_variant 0.12
katG 2155104 c.1008G>C synonymous_variant 0.19
katG 2155375 p.Val246Arg missense_variant 0.13
katG 2155377 c.735G>C synonymous_variant 0.12
katG 2155389 c.723C>G synonymous_variant 0.13
katG 2155632 c.480A>C synonymous_variant 0.17
katG 2155638 p.Lys158Ser missense_variant 0.15
katG 2155716 c.396T>C synonymous_variant 0.13
katG 2155722 c.390G>C synonymous_variant 0.12
katG 2155728 c.384G>C synonymous_variant 0.13
katG 2155735 p.Met126Gln missense_variant 0.13
katG 2155741 p.Gly124Ser missense_variant 0.14
katG 2155743 c.369G>C synonymous_variant 0.14
katG 2155747 p.Ala122Gly missense_variant 0.14
katG 2156181 c.-70T>C upstream_gene_variant 0.17
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.67
PPE35 2170053 p.Thr187Ser missense_variant 0.73
PPE35 2170147 p.Ser156Ala missense_variant 0.29
PPE35 2170159 p.Ala152Ser missense_variant 0.38
PPE35 2170274 p.Asn113Lys missense_variant 0.22
Rv1979c 2222686 p.Lys160Arg missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289702 c.-461T>G upstream_gene_variant 0.22
pncA 2289945 c.-704T>C upstream_gene_variant 0.12
kasA 2518809 p.Lys232Arg missense_variant 0.14
kasA 2519079 p.Glu322Gly missense_variant 0.27
eis 2714329 p.Asp335Val missense_variant 0.13
folC 2747100 p.Pro167Ser missense_variant 0.13
pepQ 2860222 p.Ser66Leu missense_variant 0.14
pepQ 2860585 c.-167G>C upstream_gene_variant 0.18
ribD 2987506 p.Leu223Gln missense_variant 0.22
Rv2752c 3065257 p.Met312Thr missense_variant 0.14
Rv2752c 3065647 p.Pro182Leu missense_variant 0.12
Rv2752c 3066126 c.65delG frameshift_variant 0.14
fbiD 3339419 p.Arg101Leu missense_variant 0.12
Rv3236c 3612526 c.591G>T synonymous_variant 0.2
alr 3840245 c.1176C>T synonymous_variant 0.18
rpoA 3877776 c.732T>A synonymous_variant 0.18
rpoA 3878100 c.408C>G synonymous_variant 0.12
clpC1 4038721 p.Leu662Met missense_variant 0.25
clpC1 4038743 p.Thr654Val missense_variant 0.15
clpC1 4038746 c.1959C>T synonymous_variant 0.19
clpC1 4038749 c.1956C>G synonymous_variant 0.19
clpC1 4038752 c.1953G>A synonymous_variant 0.15
clpC1 4038755 p.Gly650Ala missense_variant 0.38
clpC1 4038767 c.1938G>T synonymous_variant 0.36
clpC1 4038773 c.1932T>C synonymous_variant 0.36
clpC1 4038779 c.1926C>G synonymous_variant 0.32
clpC1 4038782 p.Val641Ile missense_variant 0.32
clpC1 4038801 p.Tyr635Phe missense_variant 0.42
clpC1 4038806 p.Glu633Asp missense_variant 0.37
clpC1 4038812 c.1893T>C synonymous_variant 0.37
clpC1 4038830 c.1875C>T synonymous_variant 0.33
clpC1 4038860 c.1845G>C synonymous_variant 0.18
clpC1 4038863 c.1842G>C synonymous_variant 0.17
clpC1 4038875 c.1830C>G synonymous_variant 0.33
clpC1 4038878 c.1827A>G synonymous_variant 0.41
clpC1 4038896 c.1809C>G synonymous_variant 0.3
clpC1 4039022 c.1683A>G synonymous_variant 0.2
clpC1 4039031 c.1674T>G synonymous_variant 0.17
clpC1 4039061 c.1644G>A synonymous_variant 0.12
clpC1 4039257 p.Gln483Leu missense_variant 0.15
clpC1 4039266 p.Asp480Thr missense_variant 0.15
clpC1 4039382 c.1323C>G synonymous_variant 0.29
clpC1 4039391 c.1314T>G synonymous_variant 0.33
clpC1 4039397 c.1308A>G synonymous_variant 0.29
clpC1 4039403 p.Glu434Asp missense_variant 0.29
clpC1 4039409 c.1296T>C synonymous_variant 0.23
clpC1 4039412 p.Ala431Val missense_variant 0.23
clpC1 4039415 p.Glu430Asp missense_variant 0.23
clpC1 4039430 c.1275T>C synonymous_variant 0.23
clpC1 4039434 p.Phe424Tyr missense_variant 0.23
clpC1 4039442 c.1263A>G synonymous_variant 0.13
clpC1 4039448 c.1257A>G synonymous_variant 0.24
clpC1 4039454 c.1251A>G synonymous_variant 0.27
clpC1 4039457 c.1248C>G synonymous_variant 0.27
clpC1 4039463 c.1242C>G synonymous_variant 0.25
clpC1 4039466 c.1239T>G synonymous_variant 0.25
clpC1 4039469 c.1236T>C synonymous_variant 0.25
clpC1 4039481 p.Ala408Ser missense_variant 0.25
clpC1 4039484 c.1221T>G synonymous_variant 0.25
clpC1 4039487 c.1218G>C synonymous_variant 0.29
clpC1 4039502 c.1203C>T synonymous_variant 0.33
clpC1 4039508 c.1197G>C synonymous_variant 0.29
clpC1 4039523 c.1182C>T synonymous_variant 0.12
clpC1 4039532 p.Asn391Ser missense_variant 0.25
clpC1 4039541 c.1164C>G synonymous_variant 0.31
clpC1 4039544 c.1161C>T synonymous_variant 0.25
clpC1 4039553 p.Thr384Gln missense_variant 0.25
clpC1 4039559 c.1146C>G synonymous_variant 0.25
clpC1 4039562 c.1143C>G synonymous_variant 0.23
clpC1 4039570 p.Met379Leu missense_variant 0.25
clpC1 4039574 p.Ala377Ser missense_variant 0.25
clpC1 4039577 c.1128T>C synonymous_variant 0.21
clpC1 4039622 c.1083C>G synonymous_variant 0.32
clpC1 4039640 c.1065C>G synonymous_variant 0.35
clpC1 4039647 p.Glu353Ser missense_variant 0.3
clpC1 4039651 p.Val352Leu missense_variant 0.29
clpC1 4039654 p.Thr351Ser missense_variant 0.27
clpC1 4039661 p.Gly348Ala missense_variant 0.26
clpC1 4039670 p.Val345Ile missense_variant 0.23
clpC1 4039682 c.1023C>G synonymous_variant 0.33
clpC1 4039685 c.1020C>G synonymous_variant 0.33
clpC1 4039697 c.1008C>T synonymous_variant 0.19
clpC1 4039708 c.996_997insTG frameshift_variant 0.21
clpC1 4039712 c.991_992delTA frameshift_variant 0.26
clpC1 4039736 c.969C>G synonymous_variant 0.14
clpC1 4039739 c.966C>G synonymous_variant 0.14
clpC1 4039751 c.954A>G synonymous_variant 0.14
clpC1 4039789 p.Ser306Thr missense_variant 0.12
clpC1 4039790 c.915C>G synonymous_variant 0.12
clpC1 4039814 c.891C>G synonymous_variant 0.23
clpC1 4039820 c.885T>G synonymous_variant 0.14
clpC1 4039832 c.873C>G synonymous_variant 0.16
clpC1 4039838 c.867G>C synonymous_variant 0.33
clpC1 4039850 c.855T>C synonymous_variant 0.28
clpC1 4039865 c.840T>C synonymous_variant 0.28
clpC1 4039868 c.837C>G synonymous_variant 0.28
clpC1 4039875 p.Asn277Arg missense_variant 0.33
clpC1 4039886 c.819C>G synonymous_variant 0.44
clpC1 4039898 c.807C>G synonymous_variant 0.48
clpC1 4039904 c.801A>G synonymous_variant 0.43
clpC1 4039913 c.792C>T synonymous_variant 0.42
clpC1 4039919 c.786C>G synonymous_variant 0.42
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.3
clpC1 4039943 p.Ser254Ala missense_variant 0.24
clpC1 4039946 c.759A>T synonymous_variant 0.39
clpC1 4039958 c.747G>C synonymous_variant 0.39
clpC1 4039979 c.726C>G synonymous_variant 0.51
clpC1 4040000 p.His235Lys missense_variant 0.38
clpC1 4040003 c.702G>C synonymous_variant 0.37
clpC1 4040009 p.Ala232Lys missense_variant 0.37
clpC1 4040021 c.684A>G synonymous_variant 0.52
clpC1 4040024 c.681A>G synonymous_variant 0.52
clpC1 4040030 c.675C>G synonymous_variant 0.52
clpC1 4040033 c.672G>C synonymous_variant 0.52
clpC1 4040042 c.663C>T synonymous_variant 0.53
clpC1 4040057 c.648C>T synonymous_variant 0.5
clpC1 4040060 p.Ile215Val missense_variant 0.48
clpC1 4040066 c.639G>C synonymous_variant 0.5
clpC1 4040072 c.633C>T synonymous_variant 0.49
clpC1 4040084 c.621C>T synonymous_variant 0.47
clpC1 4040087 c.618G>C synonymous_variant 0.47
clpC1 4040090 c.615T>C synonymous_variant 0.47
clpC1 4040093 c.610_612delCTCinsTTG synonymous_variant 0.47
clpC1 4040117 c.588A>G synonymous_variant 0.52
clpC1 4040123 p.Glu194Asp missense_variant 0.35
clpC1 4040126 c.579C>G synonymous_variant 0.33
clpC1 4040144 c.561G>C synonymous_variant 0.13
clpC1 4040324 c.381G>C synonymous_variant 0.18
clpC1 4040330 c.375C>G synonymous_variant 0.26
clpC1 4040354 c.351A>G synonymous_variant 0.29
clpC1 4040357 c.348T>C synonymous_variant 0.25
clpC1 4040363 c.342A>T synonymous_variant 0.21
clpC1 4040411 c.294T>C synonymous_variant 0.13
clpC1 4040480 c.225T>G synonymous_variant 0.26
panD 4044299 c.-18A>T upstream_gene_variant 0.25
embC 4240873 c.1011C>A synonymous_variant 0.14
embC 4241632 p.Phe590Leu missense_variant 0.25
embC 4241717 p.Arg619Trp missense_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4245539 c.-975C>A upstream_gene_variant 0.2
embB 4247956 c.1443G>A synonymous_variant 0.2
embB 4249370 c.2857C>T synonymous_variant 0.13
aftB 4267816 p.Ala341Ser missense_variant 0.14
aftB 4269108 c.-272C>A upstream_gene_variant 0.15
ethA 4326965 p.Asp170Gly missense_variant 0.12
ethA 4327088 p.Leu129Pro missense_variant 0.13
ethR 4327607 p.Pro20Gln missense_variant 0.12
whiB6 4338392 p.Thr44Ser missense_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0