Run ID: ERR11049020
Sample name:
Date: 2024-10-04T13:51:45.346333
Number of reads: 2418913
Percentage reads mapped: 89.65
Median coverage: 73.5
Strain: lineage4.8
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
La1.2.BCG | M.bovis | None | 0.12 |
lineage4 | Euro-American | None | 1.0 |
lineage4.8 | Euro-American (mainly T) | RD219 | 0.95 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 882 | c.882C>T | synonymous_variant | 0.14 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.15 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.15 | isoniazid | |
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
mshA | 576347 | p.Thr334Ala | missense_variant | 1.0 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.14 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.19 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620421 | c.531G>C | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620424 | c.534G>C | synonymous_variant | 0.21 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620433 | c.543C>G | synonymous_variant | 0.2 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>A | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620460 | c.570T>G | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620461 | p.Val191Ile | missense_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620649 | c.759A>G | synonymous_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620659 | c.769_771delCGCinsAGG | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620664 | c.774C>T | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620678 | p.Pro263Leu | missense_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620682 | c.792G>A | synonymous_variant | 0.34 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620688 | c.798G>C | synonymous_variant | 0.34 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620710 | p.Val274Ile | missense_variant | 0.3 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620742 | c.852G>C | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620745 | c.855G>C | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 0.28 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620763 | c.873G>A | synonymous_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620769 | c.879C>G | synonymous_variant | 0.24 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.21 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620784 | c.894C>G | synonymous_variant | 0.21 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620790 | c.900C>T | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620796 | c.906C>G | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620809 | c.919C>T | synonymous_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 656265 | c.1206G>C | synonymous_variant | 0.16 | ethionamide | |
Rv0565c | 656268 | p.Met401Ile | missense_variant | 0.16 | ethionamide | |
Rv0565c | 656277 | c.1194C>G | synonymous_variant | 0.15 | ethionamide | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.17 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 0.16 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.28 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.29 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.3 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.29 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.34 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.38 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.42 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.42 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.42 | isoniazid | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.18 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.19 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.19 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
nusG | 734596 | c.343T>C | synonymous_variant | 0.15 | rifampicin | |
nusG | 734601 | c.348C>G | synonymous_variant | 0.18 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.16 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.16 | rifampicin | |
nusG | 734703 | c.450T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.15 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.39 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.38 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.19 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.14 | rifampicin | |
rpoB | 761374 | p.Val523Asp | missense_variant | 0.15 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761439 | p.Asp545Asn | missense_variant | 0.14 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.14 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.2 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.2 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.34 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.34 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.23 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.31 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.35 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.32 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.31 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 762581 | c.-789T>C | upstream_gene_variant | 0.15 | rifampicin | |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.14 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762926 | c.3120C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.29 | rifampicin | |
rpoC | 763025 | c.-345C>T | upstream_gene_variant | 0.24 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.34 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.34 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.28 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.28 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.29 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.17 | rifampicin | |
rpoB | 763268 | c.3462C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.25 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.26 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.16 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.16 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.2 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.19 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.25 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.25 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.32 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.49 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.49 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.27 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765292 | c.1923G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.29 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.3 | rifampicin | Uncertain significance |
rpoC | 765329 | p.Ser654Gly | missense_variant | 0.3 | rifampicin | |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.38 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.33 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.33 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.34 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766660 | c.3291G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.19 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.32 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.29 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.32 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.34 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.32 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.16 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775913 | c.2568C>G | synonymous_variant | 0.16 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775916 | c.2565T>C | synonymous_variant | 0.17 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775921 | c.2560C>T | synonymous_variant | 0.16 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.15 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775943 | c.2538C>G | synonymous_variant | 0.16 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.17 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775973 | c.2506_2508delTTGinsCTC | synonymous_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.18 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775991 | c.2490G>A | synonymous_variant | 0.18 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775997 | c.2484T>C | synonymous_variant | 0.17 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776000 | p.Leu827Ile | missense_variant | 0.16 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776005 | p.Ile826Leu | missense_variant | 0.16 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 0.17 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776030 | c.2451G>A | synonymous_variant | 0.15 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777101 | c.1380C>G | synonymous_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777110 | c.1371T>G | synonymous_variant | 0.18 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777115 | p.Met456Leu | missense_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777116 | c.1365C>T | synonymous_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777133 | p.Val450Ile | missense_variant | 0.2 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777158 | c.1323C>G | synonymous_variant | 0.25 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777164 | c.1317C>G | synonymous_variant | 0.24 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777170 | c.1311T>C | synonymous_variant | 0.21 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.21 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777191 | c.1290C>G | synonymous_variant | 0.18 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777194 | c.1287A>G | synonymous_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777206 | c.1275A>G | synonymous_variant | 0.2 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777212 | p.Ala423Thr | missense_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777215 | c.1266C>G | synonymous_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777218 | c.1263G>A | synonymous_variant | 0.18 | bedaquiline | |
clofazimine | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.2 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.22 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.39 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.42 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.37 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.35 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.3 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.36 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.33 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.41 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.18 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.16 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.19 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.19 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.19 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.16 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.16 | linezolid | |
rplC | 800875 | p.Val23Ile | missense_variant | 0.14 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.15 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.18 | linezolid | |
rplC | 800892 | c.84G>C | synonymous_variant | 0.18 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.16 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.15 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.15 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.23 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.23 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.24 | linezolid | |
rplC | 801264 | c.456C>T | synonymous_variant | 0.22 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.22 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.2 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801285 | c.477G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.19 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.18 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.17 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.2 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801341 | p.Leu178His | missense_variant | 0.14 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.15 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.14 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.15 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.16 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.17 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.2 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.22 | linezolid | |
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.14 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.14 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304546 | p.Val539Ala | missense_variant | 0.14 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304553 | c.1623C>T | synonymous_variant | 0.14 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
sigE | 1364847 | c.435G>C | synonymous_variant | 0.17 | pyrazinamide | |
sigE | 1364856 | c.444C>G | synonymous_variant | 0.17 | pyrazinamide | |
sigE | 1364862 | c.450C>A | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364868 | c.456T>G | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364887 | c.475_477delTTAinsCTG | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1364898 | c.486C>T | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364904 | p.Asp164Glu | missense_variant | 0.18 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364943 | c.531C>T | synonymous_variant | 0.15 | pyrazinamide | |
atpE | 1460831 | c.-214T>C | upstream_gene_variant | 0.14 | bedaquiline | |
atpE | 1460840 | c.-205A>G | upstream_gene_variant | 0.14 | bedaquiline | |
atpE | 1461107 | c.63C>G | synonymous_variant | 0.15 | bedaquiline | |
atpE | 1461113 | c.69C>T | synonymous_variant | 0.17 | bedaquiline | |
atpE | 1461132 | p.Val30Ile | missense_variant | 0.2 | bedaquiline | |
atpE | 1461149 | c.105T>G | synonymous_variant | 0.2 | bedaquiline | |
atpE | 1461150 | p.Ile36Val | missense_variant | 0.19 | bedaquiline | |
atpE | 1461158 | c.114T>G | synonymous_variant | 0.18 | bedaquiline | |
atpE | 1461159 | p.Val39Ile | missense_variant | 0.18 | bedaquiline | Uncertain significance |
atpE | 1461170 | c.126A>G | synonymous_variant | 0.18 | bedaquiline | |
atpE | 1461185 | c.141G>T | synonymous_variant | 0.17 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.17 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.18 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.19 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472045 | n.200T>A | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.21 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472300 | n.455C>T | non_coding_transcript_exon_variant | 0.37 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.38 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.43 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.4 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.24 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1474409 | n.756_766delACCCACACGCG | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1474427 | n.770A>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474429 | n.772G>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474431 | n.774_775delGCinsTTTGGG | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474435 | n.780_783delGAAT | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1475013 | n.1356G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.58 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.13 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.14 | isoniazid | |
ethionamide | ||||||
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834081 | c.540C>T | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.14 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.17 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.29 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.28 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.29 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.23 | pyrazinamide | |
tsnR | 1853370 | c.-236G>T | upstream_gene_variant | 0.14 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.16 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.14 | linezolid | |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2101804 | c.1239T>G | synonymous_variant | 0.15 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101808 | p.Thr412Ser | missense_variant | 0.17 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101830 | p.Ile405Val | missense_variant | 0.23 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101837 | p.Ala402Val | missense_variant | 0.2 | isoniazid | Uncertain significance |
delamanid | ||||||
ethionamide | Uncertain significance | |||||
ndh | 2101858 | p.LeuIle394PheAla | missense_variant | 0.22 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101872 | p.Ile391Phe | missense_variant | 0.22 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101873 | p.Phe390Leu | missense_variant | 0.22 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101885 | c.1158G>A | synonymous_variant | 0.25 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101888 | c.1155T>C | synonymous_variant | 0.24 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101894 | c.1149T>G | synonymous_variant | 0.24 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101912 | c.1131G>C | synonymous_variant | 0.24 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101920 | c.1123A>C | synonymous_variant | 0.23 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 0.21 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101939 | c.1104A>G | synonymous_variant | 0.21 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101960 | c.1083A>G | synonymous_variant | 0.17 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101963 | c.1080G>A | synonymous_variant | 0.16 | isoniazid | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
ethionamide | Not assoc w R - Interim | |||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
Rv1979c | 2223491 | c.-327C>A | upstream_gene_variant | 1.0 | bedaquiline | Uncertain significance |
clofazimine | Not assoc w R | |||||
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.32 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.2 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.19 | isoniazid | |
kasA | 2518132 | c.18C>T | synonymous_variant | 0.13 | isoniazid | |
kasA | 2518146 | p.Phe11Tyr | missense_variant | 0.14 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.15 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518693 | c.579C>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.17 | isoniazid | |
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782928 | p.Thr372Glu | missense_variant | 0.14 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.14 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783464 | c.579A>G | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>C | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.16 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783557 | c.486T>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.48 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.49 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.24 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.24 | kanamycin | Not assoc w R - Interim |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.18 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
thyX | 3067652 | c.294T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067691 | p.Ile85Leu | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074061 | c.411A>G | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyA | 3074079 | c.393G>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3074097 | c.375C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3074100 | p.Asp124Asn | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3074106 | c.366T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074127 | c.345G>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074130 | c.342G>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3074154 | c.318T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074157 | c.315C>G | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3074160 | c.312A>G | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3074163 | p.Ala103Thr | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074172 | c.300G>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074175 | c.297A>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074181 | c.291A>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074187 | c.285T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074214 | c.258T>C | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
ald | 3087420 | p.Ile201Val | missense_variant | 1.0 | cycloserine | |
Rv3083 | 3448507 | c.5_*1408del | frameshift_variant&stop_lost&splice_region_variant | 1.0 | ethionamide | Uncertain significance |
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627071 | c.279G>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627299 | c.-688_-686delTTGinsCTA | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877515 | c.993G>C | synonymous_variant | 0.15 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.22 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.24 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.28 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.34 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3877890 | c.618C>T | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.34 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.33 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3877923 | c.585C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3878043 | c.465G>A | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878058 | c.450G>T | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878082 | c.426T>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.25 | rifampicin | Uncertain significance |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.25 | rifampicin | Uncertain significance |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3878172 | c.336G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878181 | c.327C>T | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.23 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3878340 | c.168C>T | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878364 | c.144A>T | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878424 | c.84G>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.22 | rifampicin | |
rpoA | 3878478 | c.30C>G | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878484 | c.24C>A | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878490 | c.18C>A | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878496 | c.12A>T | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.14 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.18 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.22 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3878860 | c.-353C>T | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.24 | rifampicin | Uncertain significance |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.31 | rifampicin | Uncertain significance |
rpoA | 3878938 | c.-431T>A | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.29 | rifampicin | Uncertain significance |
rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.32 | rifampicin | Uncertain significance |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.33 | rifampicin | Uncertain significance |
rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.28 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.14 | rifampicin | |
rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 0.14 | rifampicin | |
rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 0.14 | rifampicin | |
ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.15 | pretomanid | |
delamanid | ||||||
ddn | 3986648 | c.-196C>G | upstream_gene_variant | 0.14 | pretomanid | |
delamanid | ||||||
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038821 | c.1884G>A | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.17 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.18 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039625 | c.1080G>A | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
glpK | 4138643 | c.1113A>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138646 | c.1110G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138654 | c.1102C>T | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138679 | p.Met359Val | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138721 | c.1035G>A | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138730 | c.1026C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138757 | c.999A>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138763 | c.993G>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138769 | c.987G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138774 | p.Ser328Ala | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138778 | c.978C>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138796 | c.960A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138802 | c.954G>A | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138808 | c.948G>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138817 | c.939T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138822 | p.Asn312Asp | missense_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4241107 | c.1245G>C | synonymous_variant | 0.14 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.19 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.15 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4241170 | c.1308G>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4241173 | c.1311C>T | synonymous_variant | 0.17 | ethambutol | |
embC | 4241203 | c.1341T>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4241206 | c.1344G>C | synonymous_variant | 0.14 | ethambutol | Not assoc w R - Interim |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4242820 | c.-413G>C | upstream_gene_variant | 0.15 | ethambutol | |
embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.16 | ethambutol | |
embA | 4242838 | c.-395C>G | upstream_gene_variant | 0.15 | ethambutol | |
embB | 4249444 | c.2931T>C | synonymous_variant | 0.15 | ethambutol | |
embB | 4249469 | p.Leu986Met | missense_variant | 0.2 | ethambutol | |
embB | 4249486 | c.2973T>G | synonymous_variant | 0.24 | ethambutol | |
embB | 4249498 | c.2985G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4249521 | p.Ala1003Val | missense_variant | 0.18 | ethambutol | |
embB | 4249525 | c.3012T>C | synonymous_variant | 0.15 | ethambutol | Not assoc w R - Interim |
embB | 4249532 | p.Ala1007Thr | missense_variant | 0.15 | ethambutol | Uncertain significance |
embB | 4249543 | c.3030G>C | synonymous_variant | 0.15 | ethambutol | |
embB | 4249546 | c.3033G>A | synonymous_variant | 0.15 | ethambutol | |
embB | 4249558 | c.3045A>C | synonymous_variant | 0.14 | ethambutol | |
embB | 4249568 | p.Ser1019Thr | missense_variant | 0.14 | ethambutol | |
embB | 4249573 | c.3060T>C | synonymous_variant | 0.14 | ethambutol | |
embB | 4249580 | p.Leu1023Met | missense_variant | 0.13 | ethambutol | |
aftB | 4268096 | c.741C>G | synonymous_variant | 0.17 | ethambutol | |
aftB | 4268099 | c.738G>C | synonymous_variant | 0.18 | ethambutol | |
aftB | 4268102 | c.735C>G | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
aftB | 4268117 | c.720G>C | synonymous_variant | 0.23 | ethambutol | |
aftB | 4268123 | p.Ser238Gly | missense_variant | 0.22 | ethambutol | |
aftB | 4268129 | c.708T>G | synonymous_variant | 0.22 | ethambutol | |
aftB | 4268138 | c.699A>C | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
aftB | 4268144 | c.693T>C | synonymous_variant | 0.22 | ethambutol | |
aftB | 4268164 | p.Gln225Glu | missense_variant | 0.22 | ethambutol | |
aftB | 4268169 | p.Ala223Gly | missense_variant | 0.21 | ethambutol | |
aftB | 4268171 | c.666G>C | synonymous_variant | 0.21 | ethambutol | |
aftB | 4268179 | c.658T>C | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
aftB | 4268182 | p.Phe219Leu | missense_variant | 0.22 | ethambutol | |
aftB | 4268183 | c.654A>T | synonymous_variant | 0.23 | ethambutol | |
aftB | 4268193 | p.Leu215Ala | missense_variant | 0.22 | ethambutol | |
aftB | 4268205 | p.Val211Ala | missense_variant | 0.21 | ethambutol | |
aftB | 4268213 | c.624T>G | synonymous_variant | 0.21 | ethambutol | |
aftB | 4268225 | c.612G>C | synonymous_variant | 0.15 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R |