TB-Profiler result

Run: ERR4818347
Summary

Run ID: ERR4818347

Sample name:

Date: 2025-09-15T14:52:28.511961

Number of reads: 2054603

Percentage reads mapped: 72.58

Median coverage: 48.0

Strain: lineage4.1.2

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 100.0
lineage4.1 Euro-American None 100.0
lineage4.1.2 Euro-American None 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide ethR p.Phe110Leu Uncertain significance Mutation from literature
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
embB 4247448 p.His312Arg missense_variant 0.18 ethambutol Mutation from literature
ethR 4327876 p.Phe110Leu missense_variant 1.0 ethionamide Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 0.16 isoniazid Uncertain significance
dnaA 534 c.534T>C synonymous_variant 0.19 isoniazid Not assoc w R - Interim
dnaA 558 c.558G>T synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 561 c.561C>T synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 567 c.567C>G synonymous_variant 0.21 isoniazid Uncertain significance
dnaA 571 c.571T>C synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 582 c.582A>C synonymous_variant 0.2 isoniazid Not assoc w R - Interim
dnaA 585 c.585A>G synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 588 c.588A>C synonymous_variant 0.19 isoniazid Uncertain significance
dnaA 591 c.591C>G synonymous_variant 0.21 isoniazid Uncertain significance
dnaA 600 c.600T>G synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 741 c.741T>C synonymous_variant 0.2 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 756 c.756T>C synonymous_variant 0.19 isoniazid Uncertain significance
dnaA 768 c.768C>G synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 771 c.771A>C synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 777 c.777A>G synonymous_variant 0.18 isoniazid Uncertain significance
dnaA 786 c.786C>T synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 897 c.897A>G synonymous_variant 0.16 isoniazid Uncertain significance
dnaA 912 c.912T>G synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 918 c.918C>G synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 921 c.921A>G synonymous_variant 0.18 isoniazid Not assoc w R - Interim
dnaA 942 c.942C>G synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 945 c.945G>A synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 955 c.955A>C synonymous_variant 0.15 isoniazid Uncertain significance
dnaA 960 c.960C>A synonymous_variant 0.13 isoniazid Uncertain significance
gyrB 6268 c.1029C>G synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6286 c.1047T>C synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6289 c.1050C>T synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6292 c.1053G>C synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6307 c.1068T>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrB 6346 c.1107C>T synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6376 c.-926G>A upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6382 c.-920A>G upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6388 c.-914T>C upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6403 c.-899T>C upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6841 c.1602T>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7147 c.-155G>C upstream_gene_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7165 c.-137C>G upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7178 c.-124T>C upstream_gene_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7186 c.1947C>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 7335 p.Leu12Val missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7347 p.Glu16Gln missense_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7355 c.54T>C synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7361 c.60C>T synonymous_variant 0.31 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 7406 c.105G>C synonymous_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7412 c.111C>G synonymous_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7427 c.126G>C synonymous_variant 0.28 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7436 c.135C>T synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7451 c.150C>G synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7457 c.156T>C synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7475 c.174A>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7484 c.183T>C synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7514 c.213C>G synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7523 c.222C>A synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8111 c.810G>C synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8121 c.820T>C synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8129 c.828T>C synonymous_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8135 c.834C>G synonymous_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8156 c.855T>C synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8168 c.867A>G synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8177 c.876A>C synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8186 c.885G>A synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8189 c.888G>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8219 c.918T>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8234 c.933T>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8247 p.Ile316Val missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8264 c.963T>C synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8267 c.966G>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8276 c.975G>A synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8283 p.Ile328Leu missense_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8330 c.1029C>G synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8340 p.Ala347Ser missense_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 8382 p.Leu361Met missense_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8387 c.1086C>T synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8391 p.Tyr364His missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8405 c.1104C>T synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8636 c.1335A>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8672 c.1371A>G synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.27 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8693 c.1392T>C synonymous_variant 0.27 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8696 c.1395G>C synonymous_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8699 c.1398A>G synonymous_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8711 c.1410A>C synonymous_variant 0.27 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8714 c.1413A>G synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8729 c.1428T>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8730 p.Gly477Arg missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9204 p.Ser635Thr missense_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9252 p.Val651Ile missense_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 490803 c.21T>A synonymous_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 490812 c.30A>G synonymous_variant 0.27 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 490815 c.33G>C synonymous_variant 0.28 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 490827 c.45C>T synonymous_variant 0.3 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 490848 c.66A>G synonymous_variant 0.27 clofazimine Not assoc w R - Interim
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
fgd1 490851 c.69A>T synonymous_variant 0.27 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 490868 p.Ala29Gly missense_variant 0.26 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491172 c.390C>A synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491181 c.399T>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491191 p.Gly137Arg missense_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491202 c.420G>C synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491203 p.Gln141Glu missense_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491212 p.Ser144Arg missense_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491217 c.435T>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491591 p.Lys270Met missense_variant 0.79 clofazimine Not assoc w R
delamanid Uncertain significance
pretomanid Uncertain significance
mshA 575821 c.474G>C synonymous_variant 0.19 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575824 c.477T>G synonymous_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575830 c.483C>G synonymous_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575833 c.486C>G synonymous_variant 0.16 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575845 c.498C>T synonymous_variant 0.16 ethionamide Uncertain significance
isoniazid Not assoc w R - Interim
mshA 575864 c.517T>C synonymous_variant 0.16 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575893 c.546C>G synonymous_variant 0.16 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575896 c.549G>C synonymous_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575908 c.561A>G synonymous_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575917 p.Asp190Glu missense_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575920 c.573C>G synonymous_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575924 p.Gly193Ser missense_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575944 c.597T>C synonymous_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575965 c.618C>G synonymous_variant 0.17 ethionamide Uncertain significance
isoniazid Not assoc w R - Interim
ccsA 620412 c.522T>C synonymous_variant 0.2 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620415 c.525T>C synonymous_variant 0.19 amikacin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620424 c.534G>C synonymous_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620433 c.543C>G synonymous_variant 0.19 amikacin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.18 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620439 c.549T>C synonymous_variant 0.18 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620442 c.552G>C synonymous_variant 0.16 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620445 c.555A>G synonymous_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620460 c.570T>G synonymous_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620461 p.Val191Ile missense_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620481 c.591T>G synonymous_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620682 c.792G>A synonymous_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620688 c.798G>C synonymous_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
Rv0565c 656088 c.1383A>G synonymous_variant 0.15 ethionamide Uncertain significance
Rv0565c 656091 c.1380T>C synonymous_variant 0.16 ethionamide Uncertain significance
Rv0565c 656219 p.His418Tyr missense_variant 0.14 ethionamide Uncertain significance
Rv0565c 656265 c.1206G>C synonymous_variant 0.17 ethionamide Uncertain significance
Rv0565c 656268 p.Met401Ile missense_variant 0.16 ethionamide Uncertain significance
Rv0565c 656277 c.1194C>G synonymous_variant 0.17 ethionamide Uncertain significance
Rv0565c 656418 c.1053A>G synonymous_variant 0.17 ethionamide Uncertain significance
Rv0565c 656423 c.1048T>C synonymous_variant 0.19 ethionamide Uncertain significance
Rv0565c 656448 p.Ile341Val missense_variant 0.23 ethionamide Uncertain significance
Rv0565c 656454 c.1017G>C synonymous_variant 0.26 ethionamide Uncertain significance
Rv0565c 656457 c.1014T>C synonymous_variant 0.25 ethionamide Uncertain significance
Rv0565c 656469 c.1002T>C synonymous_variant 0.25 ethionamide Uncertain significance
Rv0565c 656475 c.996A>G synonymous_variant 0.24 ethionamide Uncertain significance
Rv0565c 657259 p.Tyr71Phe missense_variant 0.15 ethionamide Uncertain significance
Rv0565c 657264 c.207T>C synonymous_variant 0.16 ethionamide Uncertain significance
Rv0565c 657269 p.Ser68Pro missense_variant 0.79 ethionamide Uncertain significance
Rv0565c 657300 c.171C>G synonymous_variant 0.26 ethionamide Uncertain significance
Rv0565c 657318 c.153T>C synonymous_variant 0.21 ethionamide Uncertain significance
Rv0565c 657324 c.147C>G synonymous_variant 0.2 ethionamide Uncertain significance
Rv0565c 657327 c.144C>G synonymous_variant 0.19 ethionamide Uncertain significance
Rv0565c 657337 p.Arg45Gln missense_variant 0.18 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.17 ethionamide Uncertain significance
Rv0565c 657347 c.124A>C synonymous_variant 0.15 ethionamide Uncertain significance
Rv0565c 657356 p.Ile39Val missense_variant 0.16 ethionamide Uncertain significance
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.15 ethionamide Uncertain significance
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.17 ethionamide Uncertain significance
hadA 731774 c.-156T>C upstream_gene_variant 0.15 isoniazid Uncertain significance
hadA 731792 c.-138G>A upstream_gene_variant 0.15 isoniazid Uncertain significance
hadA 731801 c.-129C>G upstream_gene_variant 0.16 isoniazid Uncertain significance
hadA 731816 c.-114G>A upstream_gene_variant 0.14 isoniazid Uncertain significance
hadA 732321 p.Glu131Ala missense_variant 0.17 isoniazid Uncertain significance
hadA 732329 p.Leu134Val missense_variant 0.19 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.22 isoniazid Uncertain significance
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.36 isoniazid Uncertain significance
hadA 732396 p.Gly156Ala missense_variant 0.39 isoniazid Uncertain significance
hadA 732398 p.Ala157Thr missense_variant 0.38 isoniazid Uncertain significance
nusG 734424 c.171G>A synonymous_variant 0.18 rifampicin Uncertain significance
nusG 734442 c.189G>A synonymous_variant 0.19 rifampicin Uncertain significance
nusG 734451 c.198G>C synonymous_variant 0.21 rifampicin Uncertain significance
nusG 734499 c.246G>C synonymous_variant 0.16 rifampicin Uncertain significance
nusG 734532 c.279A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760091 c.285G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoB 760115 c.309C>T synonymous_variant 0.76 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.24 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760181 c.375T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760235 c.429T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760328 c.522G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 760331 c.525G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760340 c.534G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760376 p.Asp190Glu missense_variant 0.17 rifampicin Uncertain significance
rpoB 760381 p.Thr192Met missense_variant 0.16 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760412 c.606C>G synonymous_variant 0.24 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.18 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.15 rifampicin Uncertain significance
rpoB 760541 c.735G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.19 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.22 rifampicin Uncertain significance
rpoB 760611 c.805T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 760674 c.868T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.25 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.25 rifampicin Uncertain significance
rpoB 760925 c.1119T>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760928 c.1122G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760934 c.1128C>T synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760946 c.1140A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 761006 c.1200C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 761027 c.1221A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.28 rifampicin Uncertain significance
rpoB 761129 c.1323G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 761165 c.1359G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.33 rifampicin Uncertain significance
rpoB 761213 c.1407G>C synonymous_variant 0.32 rifampicin Uncertain significance
rpoB 761249 c.1443A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 761606 c.1800C>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 761612 c.1806G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761657 c.1851C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761873 c.2067A>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 761885 c.2079T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 762008 c.2202C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 762167 c.2361T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 762233 c.2427G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 762362 p.Glu852Asp missense_variant 0.18 rifampicin Uncertain significance
rpoB 762369 c.2563T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 762398 c.-972T>C upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoC 762401 c.-969G>C upstream_gene_variant 0.17 rifampicin Uncertain significance
rpoB 762404 c.2598T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoB 762416 c.2610A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.23 rifampicin Uncertain significance
rpoC 762434 c.-936T>C upstream_gene_variant 0.24 rifampicin Uncertain significance
rpoB 762449 c.2643C>A synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoB 762488 c.2682G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.21 rifampicin Uncertain significance
rpoC 762509 c.-861T>G upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoB 762510 p.Ala902Pro missense_variant 0.19 rifampicin Uncertain significance
rpoC 762521 c.-849C>T upstream_gene_variant 0.15 rifampicin Uncertain significance
rpoB 762857 c.3051C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 762947 c.-423C>A upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoC 762989 c.-381G>C upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoB 762995 c.3189G>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.17 rifampicin Uncertain significance
rpoB 763040 c.3234C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.25 rifampicin Uncertain significance
rpoC 763158 c.-212C>T upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoB 763166 c.3360A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoC 763486 c.117T>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 763492 c.123G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 763660 c.291T>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 763732 c.363C>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 763741 c.372C>T synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 763744 c.375G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 763765 c.396T>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 763774 c.405G>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763807 c.438T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 763835 p.Ala156Met missense_variant 0.24 rifampicin Uncertain significance
rpoC 763853 p.Val162Ile missense_variant 0.24 rifampicin Uncertain significance
rpoC 763858 c.489A>G synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 763872 p.Gly168Ala missense_variant 0.23 rifampicin Uncertain significance
rpoC 763876 p.Glu169Asp missense_variant 0.23 rifampicin Uncertain significance
rpoC 763879 c.510A>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 763888 c.519G>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763891 c.522G>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763894 c.525A>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 763900 c.531G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764083 c.714A>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 764098 c.729A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.26 rifampicin Uncertain significance
rpoC 764112 p.Tyr248Phe missense_variant 0.24 rifampicin Uncertain significance
rpoC 764116 c.747C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 764215 c.846A>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764236 c.867G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 764365 c.996C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 764428 c.1059G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 764449 c.1080G>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 764452 c.1083T>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 764458 c.1089G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 764497 c.1128A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 764560 c.1191T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764593 c.1224C>T synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 764611 c.1242G>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 764668 c.1299C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.25 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 764888 c.1519T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>A synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 765007 c.1638T>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765150 p.Gly594Glu missense_variant 0.96 rifampicin Not assoc w R
rpoC 765292 c.1923G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 765298 c.1929G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 765300 p.Val644Ala missense_variant 0.26 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.26 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.29 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 765349 c.1980T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765361 c.1992C>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 765383 p.Met672Leu missense_variant 0.22 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.19 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 765421 c.2052C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 765541 c.2172C>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 765553 c.2184C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 765559 c.2190G>C synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 765580 c.2211G>C synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 765613 p.His748Gln missense_variant 0.32 rifampicin Uncertain significance
rpoC 765625 c.2256C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.31 rifampicin Uncertain significance
rpoC 765700 c.2331T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 765751 c.2382C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 765787 c.2418C>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 765835 c.2466C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 765892 c.2523T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 765994 c.2625A>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 766021 c.2652G>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 766027 c.2658G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 766043 p.Gln892Glu missense_variant 0.21 rifampicin Uncertain significance
rpoC 766054 c.2685C>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766082 p.Ala905Gln missense_variant 0.18 rifampicin Uncertain significance
rpoC 766096 c.2727G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 766129 c.2760C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 766447 c.3078T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 766462 c.3093G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 766483 c.3114G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766484 p.Val1039Ile missense_variant 0.19 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766522 c.3153C>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766528 c.3159T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766531 c.3162G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766540 p.Asp1057Glu missense_variant 0.18 rifampicin Uncertain significance
rpoC 766549 c.3180G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 766607 p.Ile1080Leu missense_variant 0.17 rifampicin Uncertain significance
rpoC 766657 c.3288A>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 766673 p.Gly1102Asn missense_variant 0.17 rifampicin Uncertain significance
rpoC 766726 c.3357T>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 766738 c.3369G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 766765 c.3396A>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 766801 c.3432C>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766804 c.3435A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 766900 c.3531T>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 767059 c.3690T>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 767098 c.3729T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.16 rifampicin Uncertain significance
rpoC 767284 c.3915C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 767288 c.3919C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 777101 c.1380C>G synonymous_variant 0.16 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777116 c.1365C>T synonymous_variant 0.14 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777133 p.Val450Ile missense_variant 0.18 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777158 c.1323C>G synonymous_variant 0.19 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777164 c.1317C>G synonymous_variant 0.22 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777170 c.1311T>C synonymous_variant 0.23 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777173 c.1308C>G synonymous_variant 0.23 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777176 p.Glu435Asp missense_variant 0.23 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777191 c.1290C>G synonymous_variant 0.23 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777194 c.1287A>G synonymous_variant 0.22 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777206 c.1275A>G synonymous_variant 0.19 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777212 p.Ala423Thr missense_variant 0.18 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777215 c.1266C>G synonymous_variant 0.18 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777218 c.1263G>A synonymous_variant 0.18 bedaquiline Uncertain significance
clofazimine Uncertain significance
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781595 c.36T>C synonymous_variant 0.25 streptomycin Uncertain significance
rpsL 781605 p.Ile16Val missense_variant 0.21 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.21 streptomycin Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 0.29 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.27 streptomycin Uncertain significance
rpsL 781649 c.90T>C synonymous_variant 0.31 streptomycin Uncertain significance
rpsL 781655 c.96T>C synonymous_variant 0.32 streptomycin Uncertain significance
rpsL 781700 c.141G>C synonymous_variant 0.2 streptomycin Uncertain significance
rpsL 781703 c.144G>T synonymous_variant 0.21 streptomycin Uncertain significance
rpsL 781715 c.156T>C synonymous_variant 0.22 streptomycin Uncertain significance
rpsL 781728 c.169T>C synonymous_variant 0.22 streptomycin Uncertain significance
rpsL 781736 c.177T>C synonymous_variant 0.21 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 0.23 streptomycin Uncertain significance
rpsL 781748 c.189C>G synonymous_variant 0.24 streptomycin Uncertain significance
rpsL 781754 c.195G>C synonymous_variant 0.24 streptomycin Uncertain significance
rpsL 781760 c.201T>C synonymous_variant 0.24 streptomycin Uncertain significance
rpsL 781772 c.213C>A synonymous_variant 0.22 streptomycin Uncertain significance
rpsL 781808 c.249C>T synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781811 c.252C>T synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781832 c.273T>C synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781838 c.279G>C synonymous_variant 0.19 streptomycin Uncertain significance
rpsL 781841 c.282C>G synonymous_variant 0.18 streptomycin Uncertain significance
rpsL 781865 c.306G>C synonymous_variant 0.18 streptomycin Uncertain significance
rpsL 781868 c.309T>C synonymous_variant 0.18 streptomycin Uncertain significance
rpsL 781871 c.312G>C synonymous_variant 0.18 streptomycin Uncertain significance
rpsL 781877 c.318T>C synonymous_variant 0.2 streptomycin Uncertain significance
rpsL 781892 c.333A>G synonymous_variant 0.2 streptomycin Uncertain significance
rpsL 781898 c.339A>T synonymous_variant 0.22 streptomycin Uncertain significance
rpsL 781916 c.357T>C synonymous_variant 0.2 streptomycin Uncertain significance
rpsL 781929 p.Gly124Ser missense_variant 0.21 streptomycin Uncertain significance
rplC 800200 c.-609C>G upstream_gene_variant 0.98 linezolid Uncertain significance
rplC 800537 c.-272C>T upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800546 c.-263T>G upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800567 c.-242A>G upstream_gene_variant 0.17 linezolid Uncertain significance
rplC 800582 c.-227C>G upstream_gene_variant 0.18 linezolid Uncertain significance
rplC 800612 c.-197A>G upstream_gene_variant 0.18 linezolid Uncertain significance
rplC 800618 c.-191T>C upstream_gene_variant 0.17 linezolid Uncertain significance
rplC 800627 c.-182C>T upstream_gene_variant 0.2 linezolid Uncertain significance
rplC 800715 c.-94A>C upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800720 c.-89T>C upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800723 c.-86C>G upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800747 c.-62C>G upstream_gene_variant 0.18 linezolid Uncertain significance
rplC 800771 c.-38C>T upstream_gene_variant 0.25 linezolid Uncertain significance
rplC 800794 c.-15A>G upstream_gene_variant 0.2 linezolid Uncertain significance
rplC 800796 c.-13A>G upstream_gene_variant 0.2 linezolid Uncertain significance
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.21 linezolid Uncertain significance
rplC 800814 c.6A>G synonymous_variant 0.24 linezolid Uncertain significance
rplC 800817 c.9A>T synonymous_variant 0.2 linezolid Uncertain significance
rplC 800844 c.36T>C synonymous_variant 0.16 linezolid Uncertain significance
rplC 800889 c.81C>A synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801207 c.399C>T synonymous_variant 0.18 linezolid Uncertain significance
rplC 801246 c.438C>T synonymous_variant 0.19 linezolid Uncertain significance
rplC 801249 c.441T>C synonymous_variant 0.2 linezolid Uncertain significance
rplC 801255 c.447C>T synonymous_variant 0.2 linezolid Uncertain significance
rplC 801264 c.456C>T synonymous_variant 0.16 linezolid Uncertain significance
rplC 801267 c.459A>T synonymous_variant 0.17 linezolid Uncertain significance
rplC 801270 c.462T>C synonymous_variant 0.16 linezolid Uncertain significance
rplC 801276 c.468G>C synonymous_variant 0.17 linezolid Uncertain significance
rplC 801279 c.471G>C synonymous_variant 0.17 linezolid Uncertain significance
rplC 801282 c.474G>C synonymous_variant 0.17 linezolid Uncertain significance
rplC 801285 c.477G>C synonymous_variant 0.19 linezolid Uncertain significance
rplC 801309 c.501C>G synonymous_variant 0.15 linezolid Uncertain significance
rplC 801312 c.504G>C synonymous_variant 0.16 linezolid Uncertain significance
rplC 801321 c.513C>T synonymous_variant 0.14 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.15 linezolid Uncertain significance
rplC 801367 p.Ala187Thr missense_variant 0.15 linezolid Uncertain significance
fbiC 1303797 c.867A>G synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303818 c.888C>G synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303836 c.906G>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303846 p.Phe306Val missense_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303854 c.924T>C synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303860 c.930A>C synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304127 c.1197A>G synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304132 p.Ala401Gly missense_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304142 c.1212G>C synonymous_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304161 p.Arg411Ser missense_variant 0.24 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304169 c.1239T>C synonymous_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304174 p.Val415Ala missense_variant 0.23 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304184 c.1254G>C synonymous_variant 0.23 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304187 c.1257T>C synonymous_variant 0.23 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304208 c.1278C>T synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304526 c.1596T>G synonymous_variant 0.26 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304535 c.1605G>A synonymous_variant 0.29 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304544 c.1614T>C synonymous_variant 0.28 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304545 p.Val539Thr missense_variant 0.28 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304553 c.1623C>T synonymous_variant 0.26 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304559 p.Glu543Asp missense_variant 0.31 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304565 c.1635C>G synonymous_variant 0.3 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304568 c.1638T>C synonymous_variant 0.31 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304580 c.1650T>C synonymous_variant 0.26 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304703 c.1773C>G synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304711 p.Ala594Glu missense_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304715 c.1785G>C synonymous_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304724 c.1794A>G synonymous_variant 0.19 clofazimine Not assoc w R - Interim
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
fbiC 1304727 c.1797A>G synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304742 c.1812T>C synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304757 c.1827A>G synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304778 c.1848T>C synonymous_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304784 c.1854T>C synonymous_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304787 c.1857T>G synonymous_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304808 c.1878C>G synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304811 c.1881C>G synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304817 c.1887T>C synonymous_variant 0.26 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304829 c.1899T>C synonymous_variant 0.39 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304832 c.1902C>T synonymous_variant 0.37 clofazimine Not assoc w R - Interim
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
fbiC 1304853 c.1923C>T synonymous_variant 0.65 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304856 c.1926C>G synonymous_variant 0.71 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304869 c.1939C>T synonymous_variant 0.5 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304875 p.Ile649Val missense_variant 0.47 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304883 p.Glu651Asp missense_variant 0.42 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304891 p.Ile654Thr missense_variant 0.38 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304893 p.Gly655Ser missense_variant 0.37 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304907 c.1977C>G synonymous_variant 0.43 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304910 c.1980G>C synonymous_variant 0.42 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304916 c.1986T>C synonymous_variant 0.44 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304928 c.1998T>C synonymous_variant 0.45 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304937 c.2007G>C synonymous_variant 0.49 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304958 c.2028T>G synonymous_variant 0.47 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304983 c.2053C>T synonymous_variant 0.43 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304994 c.2064A>G synonymous_variant 0.38 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304995 p.Leu689Met missense_variant 0.38 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1305006 c.2076A>G synonymous_variant 0.32 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1305012 c.2082G>C synonymous_variant 0.29 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1305015 c.2085G>C synonymous_variant 0.27 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
atpE 1460840 c.-205A>G upstream_gene_variant 0.18 bedaquiline Uncertain significance
atpE 1460852 c.-193C>G upstream_gene_variant 0.15 bedaquiline Uncertain significance
atpE 1460855 c.-190T>C upstream_gene_variant 0.15 bedaquiline Uncertain significance
atpE 1461159 p.Val39Ile missense_variant 0.16 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.2 bedaquiline Uncertain significance
atpE 1461197 c.153A>G synonymous_variant 0.17 bedaquiline Uncertain significance
atpE 1461219 c.175T>C synonymous_variant 0.19 bedaquiline Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.15 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673710 c.-492C>A upstream_gene_variant 0.22 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673716 c.-486_-485delGCinsAA upstream_gene_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673733 c.-469G>C upstream_gene_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673742 c.-460C>T upstream_gene_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673922 c.-280T>C upstream_gene_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673941 c.-261G>T upstream_gene_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673955 c.-247G>C upstream_gene_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674114 c.-88T>A upstream_gene_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674126 c.-76G>C upstream_gene_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674132 c.-70T>C upstream_gene_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674136 c.-66T>G upstream_gene_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674141 c.-61T>C upstream_gene_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674537 c.336C>G synonymous_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674542 p.Ala114Glu missense_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674546 c.345T>C synonymous_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674549 c.348G>C synonymous_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674555 c.354G>A synonymous_variant 0.23 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.23 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674582 c.381T>C synonymous_variant 0.22 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674585 c.384T>C synonymous_variant 0.25 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674589 p.Met130Leu missense_variant 0.25 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674601 p.Leu134Thr missense_variant 0.25 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674604 c.403C>T synonymous_variant 0.25 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674624 c.423A>C synonymous_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674630 c.429C>G synonymous_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674660 c.459G>C synonymous_variant 0.16 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674672 c.471C>G synonymous_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674703 c.502T>C synonymous_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674708 c.507G>A synonymous_variant 0.19 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674718 c.517A>C synonymous_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674741 c.540C>T synonymous_variant 0.15 ethionamide Uncertain significance
isoniazid Not assoc w R - Interim
rpsA 1833554 p.Thr5Ala missense_variant 0.21 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1833595 c.54T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1833661 c.120A>G synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833667 c.126C>G synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833721 c.180A>G synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1833724 c.183C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1833727 c.186G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1833742 c.201A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833745 c.204G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833748 c.207C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833787 c.246C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1833802 c.261A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833811 c.270G>T synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1833838 c.297G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1833841 c.300C>G synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1833847 c.306C>G synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1833856 c.315A>G synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1833874 c.333T>C synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833928 c.387G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1833940 c.399C>G synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1833971 c.430C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1833979 c.438T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834000 c.459G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834021 c.480C>T synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834030 c.489C>G synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834169 p.Thr210Ala missense_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834195 c.654G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834204 c.663C>T synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834210 c.669C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834222 c.681T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834249 c.708T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834261 c.720A>G synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834303 c.762T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834306 c.765T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834411 c.870T>C synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1834417 c.876G>C synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1834423 c.882G>C synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1834435 c.894G>C synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1834451 c.910T>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834465 c.924T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834489 c.948T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1834510 c.969C>T synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
rpsA 1834513 c.972C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834540 c.999G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834546 c.1005T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834555 c.1014T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834609 c.1068T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834619 c.1078T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834633 c.1092A>G synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834639 c.1098T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834654 p.Glu371Asp missense_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834690 c.1149T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834732 c.1191T>C synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1834733 p.Ala398Ser missense_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834753 c.1212T>C synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834765 p.Glu408Asp missense_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834775 p.Ala412Thr missense_variant 0.39 pyrazinamide Uncertain significance
rpsA 1834780 c.1239A>G synonymous_variant 0.38 pyrazinamide Uncertain significance
rpsA 1834786 c.1245A>G synonymous_variant 0.38 pyrazinamide Uncertain significance
rpsA 1834789 c.1248T>C synonymous_variant 0.34 pyrazinamide Uncertain significance
rpsA 1834792 c.1251G>C synonymous_variant 0.34 pyrazinamide Uncertain significance
tsnR 1853361 c.-245T>C upstream_gene_variant 0.16 linezolid Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2064942 c.-214G>A upstream_gene_variant 0.21 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064948 c.-220G>C upstream_gene_variant 0.21 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064972 c.-244T>C upstream_gene_variant 0.24 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064978 c.-250G>C upstream_gene_variant 0.2 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064979 c.-251C>T upstream_gene_variant 0.2 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064984 c.-256A>G upstream_gene_variant 0.21 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064993 c.-265T>C upstream_gene_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
katG 2155641 p.Lys157Asn missense_variant 0.18 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 0.18 isoniazid Uncertain significance
katG 2155677 c.435C>G synonymous_variant 0.22 isoniazid Uncertain significance
katG 2155680 c.432G>C synonymous_variant 0.24 isoniazid Uncertain significance
katG 2155691 c.421T>C synonymous_variant 0.3 isoniazid Uncertain significance
katG 2155695 c.417C>G synonymous_variant 0.34 isoniazid Uncertain significance
katG 2155704 c.408C>G synonymous_variant 0.36 isoniazid Uncertain significance
katG 2155716 c.396T>G synonymous_variant 0.29 isoniazid Uncertain significance
katG 2155722 c.390G>C synonymous_variant 0.29 isoniazid Uncertain significance
katG 2155728 c.384G>C synonymous_variant 0.25 isoniazid Uncertain significance
katG 2155740 p.Gly124Gln missense_variant 0.19 isoniazid Uncertain significance
katG 2155743 c.369G>C synonymous_variant 0.2 isoniazid Uncertain significance
PPE35 2168303 c.2310G>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
pncA 2289987 c.-746C>T upstream_gene_variant 0.21 pyrazinamide Uncertain significance
pncA 2289991 c.-750G>C upstream_gene_variant 0.21 pyrazinamide Uncertain significance
pncA 2289994 c.-753A>G upstream_gene_variant 0.21 pyrazinamide Uncertain significance
pncA 2289997 c.-756G>C upstream_gene_variant 0.22 pyrazinamide Uncertain significance
kasA 2517950 c.-165C>G upstream_gene_variant 0.21 isoniazid Uncertain significance
kasA 2518076 c.-39C>T upstream_gene_variant 1.0 isoniazid Uncertain significance
kasA 2518138 c.24T>C synonymous_variant 0.18 isoniazid Uncertain significance
kasA 2518146 p.Phe11Tyr missense_variant 0.19 isoniazid Uncertain significance
kasA 2518162 c.48G>A synonymous_variant 0.21 isoniazid Uncertain significance
kasA 2518174 c.60A>G synonymous_variant 0.21 isoniazid Uncertain significance
kasA 2518190 p.Ser26Ala missense_variant 0.24 isoniazid Uncertain significance
kasA 2518199 p.Ile29Val missense_variant 0.23 isoniazid Uncertain significance
kasA 2518220 c.106C>T synonymous_variant 0.21 isoniazid Uncertain significance
kasA 2518474 c.360G>A synonymous_variant 0.17 isoniazid Uncertain significance
kasA 2518480 c.366T>C synonymous_variant 0.17 isoniazid Uncertain significance
kasA 2518483 c.369C>G synonymous_variant 0.17 isoniazid Uncertain significance
kasA 2518504 c.390T>C synonymous_variant 0.19 isoniazid Uncertain significance
kasA 2518506 p.Ala131Glu missense_variant 0.19 isoniazid Uncertain significance
kasA 2518519 c.405G>C synonymous_variant 0.19 isoniazid Uncertain significance
kasA 2518528 c.414C>G synonymous_variant 0.19 isoniazid Uncertain significance
kasA 2518540 c.426T>C synonymous_variant 0.22 isoniazid Uncertain significance
kasA 2518561 c.447T>C synonymous_variant 0.19 isoniazid Uncertain significance
kasA 2518567 c.453G>C synonymous_variant 0.2 isoniazid Uncertain significance
ahpC 2726638 p.Ala149Val missense_variant 0.18 isoniazid Uncertain significance
ahpC 2726645 c.453C>G synonymous_variant 0.2 isoniazid Uncertain significance
ahpC 2726657 c.465A>C synonymous_variant 0.2 isoniazid Not assoc w R - Interim
ahpC 2726672 c.480G>A synonymous_variant 0.16 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.16 isoniazid Uncertain significance
Rv2477c 2782912 p.Ser377Thr missense_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782927 p.Thr372Glu missense_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782936 c.1107G>T synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782957 c.1086A>G synonymous_variant 0.17 amikacin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783040 p.Ala335Thr missense_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783044 c.999G>A synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783048 p.Asp332Gly missense_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783059 c.984T>C synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783068 p.Asp325Glu missense_variant 0.23 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783077 c.966T>C synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783140 c.903C>G synonymous_variant 0.22 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783149 c.894G>C synonymous_variant 0.2 amikacin Not assoc w R - Interim
ethambutol Uncertain significance
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
Rv2477c 2783158 c.885A>C synonymous_variant 0.23 amikacin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
Rv2477c 2783182 c.861C>G synonymous_variant 0.23 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783185 c.858G>A synonymous_variant 0.26 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783194 c.849A>G synonymous_variant 0.27 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783221 c.822G>C synonymous_variant 0.24 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783224 c.819C>G synonymous_variant 0.23 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783230 c.813T>G synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Not assoc w R - Interim
kanamycin Uncertain significance
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
Rv2477c 2783235 c.808T>C synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783338 c.705C>T synonymous_variant 0.14 amikacin Uncertain significance
ethambutol Not assoc w R - Interim
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
Rv2477c 2783350 c.693T>C synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783353 c.690T>C synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783359 c.684G>A synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783362 c.681G>C synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783628 p.Ala139Ser missense_variant 0.2 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783656 c.387G>C synonymous_variant 0.22 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783659 c.384A>G synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783665 c.378A>G synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783674 c.369T>C synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783683 c.360A>G synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783700 p.Thr115Ser missense_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783718 c.325T>C synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783719 c.324A>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783751 p.Ile98Val missense_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783758 p.Asp95Glu missense_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783761 c.282G>C synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783920 c.123G>C synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783929 c.114C>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783932 c.111C>T synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783938 c.105T>C synonymous_variant 0.22 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783953 c.90G>A synonymous_variant 0.25 amikacin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
Rv2477c 2783962 c.81T>C synonymous_variant 0.23 amikacin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Uncertain significance
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.23 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783980 c.63C>G synonymous_variant 0.2 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783992 c.51T>C synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
Rv2680 2996085 c.-20G>A upstream_gene_variant 0.46 capreomycin Uncertain significance
Rv2680 2996136 p.Ser11Asn missense_variant 0.21 capreomycin Uncertain significance
Rv2752c 3064914 c.1278T>G synonymous_variant 0.14 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.22 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.31 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.35 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.34 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066561 c.-370A>C upstream_gene_variant 0.27 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.27 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.26 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.21 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.19 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
thyX 3067373 c.573C>G synonymous_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067391 c.555G>C synonymous_variant 0.25 para-aminosalicylic_acid Uncertain significance
thyX 3067394 c.552G>C synonymous_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067439 c.507A>G synonymous_variant 0.29 para-aminosalicylic_acid Uncertain significance
thyX 3067445 c.501C>G synonymous_variant 0.29 para-aminosalicylic_acid Uncertain significance
thyX 3067465 p.Ile161Val missense_variant 0.29 para-aminosalicylic_acid Uncertain significance
thyX 3067475 c.471A>G synonymous_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067490 c.456C>G synonymous_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067493 c.453A>G synonymous_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067515 p.Ser144Thr missense_variant 0.28 para-aminosalicylic_acid Uncertain significance
thyX 3067530 p.Ala139Ser missense_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067545 p.Glu134Ala missense_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067549 p.Thr133Ala missense_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067556 p.His130Gln missense_variant 0.23 para-aminosalicylic_acid Uncertain significance
thyX 3067559 c.387C>G synonymous_variant 0.23 para-aminosalicylic_acid Uncertain significance
thyX 3067565 p.Asp127Glu missense_variant 0.2 para-aminosalicylic_acid Uncertain significance
thyX 3067570 p.Ala126Pro missense_variant 0.23 para-aminosalicylic_acid Uncertain significance
thyX 3067577 c.369G>A synonymous_variant 0.22 para-aminosalicylic_acid Uncertain significance
thyX 3067601 p.Arg115His missense_variant 0.19 para-aminosalicylic_acid Uncertain significance
thyX 3067611 p.Lys112Thr missense_variant 0.2 para-aminosalicylic_acid Uncertain significance
thyX 3067619 c.327A>C synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067661 c.285C>G synonymous_variant 0.18 para-aminosalicylic_acid Uncertain significance
thyX 3067685 c.261A>C synonymous_variant 0.15 para-aminosalicylic_acid Uncertain significance
thyX 3067718 c.228C>G synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067721 c.225T>C synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067727 c.219A>C synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067730 c.216G>A synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067736 p.Phe70Leu missense_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067739 c.207T>C synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067762 c.184C>A synonymous_variant 0.14 para-aminosalicylic_acid Uncertain significance
thyX 3067765 p.Leu61Ile missense_variant 0.16 para-aminosalicylic_acid Uncertain significance
thyX 3067781 c.165C>G synonymous_variant 0.16 para-aminosalicylic_acid Uncertain significance
thyX 3067793 c.153T>C synonymous_variant 0.18 para-aminosalicylic_acid Uncertain significance
thyX 3067799 c.147G>A synonymous_variant 0.19 para-aminosalicylic_acid Uncertain significance
thyX 3067814 c.132T>C synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067850 c.96A>C synonymous_variant 0.2 para-aminosalicylic_acid Uncertain significance
thyA 3073812 c.660C>G synonymous_variant 0.16 para-aminosalicylic_acid Uncertain significance
thyA 3073815 c.657G>A synonymous_variant 0.2 para-aminosalicylic_acid Uncertain significance
thyA 3073824 c.648A>G synonymous_variant 0.23 para-aminosalicylic_acid Uncertain significance
thyA 3073827 c.645A>G synonymous_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyA 3073839 c.633T>C synonymous_variant 0.22 para-aminosalicylic_acid Uncertain significance
thyA 3073860 c.612C>G synonymous_variant 0.26 para-aminosalicylic_acid Uncertain significance
thyA 3073863 c.609T>C synonymous_variant 0.26 para-aminosalicylic_acid Uncertain significance
thyA 3073866 c.606C>G synonymous_variant 0.27 para-aminosalicylic_acid Uncertain significance
thyA 3073872 p.Ile200Val missense_variant 0.26 para-aminosalicylic_acid Uncertain significance
thyA 3073892 c.580T>C synonymous_variant 0.28 para-aminosalicylic_acid Uncertain significance
thyA 3073898 p.Ala192Ser missense_variant 0.25 para-aminosalicylic_acid Uncertain significance
thyA 3073959 c.513T>C synonymous_variant 0.15 para-aminosalicylic_acid Uncertain significance
thyA 3073977 c.495A>G synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
ald 3087635 c.816C>T synonymous_variant 0.15 cycloserine Uncertain significance
ald 3087649 p.Gly277Asp missense_variant 0.15 cycloserine Uncertain significance
lpqB 3624047 c.864G>C synonymous_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624050 c.861C>G synonymous_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624077 c.834G>A synonymous_variant 0.22 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3624082 c.829A>C synonymous_variant 0.25 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624092 c.817_819delAGGinsCGC synonymous_variant 0.22 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624100 c.811T>C synonymous_variant 0.22 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624101 c.810C>G synonymous_variant 0.22 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624107 c.804C>T synonymous_variant 0.23 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>G synonymous_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624119 c.792C>G synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624124 p.Leu263Val missense_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624125 c.786A>G synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624143 c.768T>C synonymous_variant 0.18 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624686 p.Glu75Gln missense_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624704 c.207G>C synonymous_variant 0.21 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624707 c.204G>C synonymous_variant 0.23 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624722 c.189C>G synonymous_variant 0.31 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.33 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624749 c.162G>A synonymous_variant 0.33 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625240 c.-330T>C upstream_gene_variant 0.25 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625243 c.-333T>G upstream_gene_variant 0.25 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625255 c.-345T>C upstream_gene_variant 0.3 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625267 c.1347T>C synonymous_variant 0.25 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.22 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625572 p.Thr348Ser missense_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625579 c.-669A>G upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625594 c.-684T>C upstream_gene_variant 0.21 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625602 c.-692T>C upstream_gene_variant 0.21 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625612 c.-702G>C upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625616 p.Arg333Ala missense_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625624 c.-714C>G upstream_gene_variant 0.21 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625636 c.978C>G synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.17 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625669 c.-759G>C upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625687 c.-777G>C upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625690 c.-780T>C upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625696 c.-786A>G upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625705 c.909C>G synonymous_variant 0.19 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.16 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625735 c.-825C>T upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625797 p.Val273Met missense_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.16 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.17 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625843 c.-933C>G upstream_gene_variant 0.21 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625849 c.-939T>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625852 c.762A>G synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.21 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625876 c.738G>C synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626759 c.591T>C synonymous_variant 0.16 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626804 c.546A>G synonymous_variant 0.19 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3626846 c.504G>A synonymous_variant 0.18 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626861 c.-248C>G upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3626869 c.481C>T synonymous_variant 0.15 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3626885 c.-272A>C upstream_gene_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627167 c.-554T>C upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627181 c.-568T>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627182 c.-569T>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3627188 c.162A>G synonymous_variant 0.22 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.23 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3627221 c.129C>T synonymous_variant 0.23 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627236 c.-623T>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3627242 c.108C>T synonymous_variant 0.21 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627263 c.-650C>T upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
fbiA 3640850 p.Glu103Gly missense_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiB 3640857 c.-678G>C upstream_gene_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiB 3640866 c.-669T>C upstream_gene_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiA 3640871 p.Ala110Gly missense_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiB 3640878 c.-657T>C upstream_gene_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiB 3640899 c.-636G>C upstream_gene_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiA 3640900 p.Gln120Asn missense_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
alr 3840263 c.1086C>T synonymous_variant 0.98 cycloserine Uncertain significance
rpoA 3877553 p.Glu319Gln missense_variant 0.15 rifampicin Uncertain significance
rpoA 3877571 p.Pro313Ala missense_variant 0.15 rifampicin Uncertain significance
rpoA 3877668 c.840A>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877679 p.Ala277Ser missense_variant 0.17 rifampicin Uncertain significance
rpoA 3877686 c.822A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877737 c.771G>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoA 3877743 c.765T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.39 rifampicin Uncertain significance
rpoA 3877818 c.690A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.27 rifampicin Uncertain significance
rpoA 3877866 c.642G>C synonymous_variant 0.3 rifampicin Uncertain significance
rpoA 3877875 c.633T>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoA 3877878 c.630G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoA 3877890 c.618C>T synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3877896 c.612G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3877900 p.Ser203Asn missense_variant 0.22 rifampicin Uncertain significance
rpoA 3877905 c.603A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.21 rifampicin Uncertain significance
rpoA 3877920 c.588G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoA 3877989 c.519A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoA 3878028 c.480G>C synonymous_variant 0.29 rifampicin Uncertain significance
rpoA 3878031 c.477T>C synonymous_variant 0.28 rifampicin Uncertain significance
rpoA 3878040 c.468T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878143 p.Gly122Asp missense_variant 0.15 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoA 3878163 c.345C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoA 3878187 c.321C>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoA 3878193 c.315T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.28 rifampicin Uncertain significance
rpoA 3878217 c.291A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878232 c.276G>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoA 3878247 c.261G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3878271 c.237T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.19 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878313 c.195G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3878364 c.144A>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3878367 c.141C>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3878376 c.132G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878385 c.123C>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878388 c.120C>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoA 3878391 c.117T>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoA 3878415 c.93C>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3878436 c.72A>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878442 c.66G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3878761 c.-254G>C upstream_gene_variant 0.29 rifampicin Uncertain significance
rpoA 3878764 c.-257A>G upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoA 3878785 c.-278T>G upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoA 3878788 c.-281G>C upstream_gene_variant 0.23 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoA 3878809 c.-302T>C upstream_gene_variant 0.21 rifampicin Uncertain significance
rpoA 3878824 c.-317G>C upstream_gene_variant 0.25 rifampicin Uncertain significance
rpoA 3878833 c.-326C>G upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.17 rifampicin Uncertain significance
rpoA 3878853 c.-346G>A upstream_gene_variant 0.17 rifampicin Uncertain significance
rpoA 3878878 c.-371T>C upstream_gene_variant 0.24 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoA 3878914 c.-407T>C upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.15 rifampicin Uncertain significance
rpoA 3878938 c.-431T>C upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoA 3878947 c.-440G>C upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.21 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoA 3878998 c.-491C>G upstream_gene_variant 0.24 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.23 rifampicin Uncertain significance
rpoA 3879013 c.-506A>G upstream_gene_variant 0.24 rifampicin Uncertain significance
rpoA 3879079 c.-572A>G upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoA 3879088 c.-581A>C upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoA 3879094 c.-587T>C upstream_gene_variant 0.29 rifampicin Uncertain significance
rpoA 3879121 c.-614T>G upstream_gene_variant 0.28 rifampicin Uncertain significance
rpoA 3879127 c.-620T>C upstream_gene_variant 0.3 rifampicin Uncertain significance
rpoA 3879154 c.-647T>C upstream_gene_variant 0.28 rifampicin Uncertain significance
rpoA 3879160 c.-653A>G upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoA 3879178 c.-671T>C upstream_gene_variant 0.23 rifampicin Uncertain significance
rpoA 3879190 c.-683C>G upstream_gene_variant 0.19 rifampicin Uncertain significance
ddn 3986636 c.-208C>G upstream_gene_variant 0.25 delamanid Uncertain significance
pretomanid Uncertain significance
ddn 3986645 c.-199G>A upstream_gene_variant 0.16 delamanid Uncertain significance
pretomanid Uncertain significance
ddn 3986646 c.-198_-196delCTCinsTTG upstream_gene_variant 0.16 delamanid Uncertain significance
pretomanid Uncertain significance
clpC1 4038293 c.2412G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038302 c.2403C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4038308 c.2397G>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038314 c.2391T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038317 c.2388G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038320 c.2385G>T synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038456 p.Val750Glu missense_variant 0.18 pyrazinamide Uncertain significance
clpC1 4038460 p.Leu749Met missense_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038596 c.2109A>G synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4038640 p.Asp689Asn missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038683 c.2022T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038701 c.2004G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4038704 c.2001T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038713 c.1992T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038749 c.1956C>G synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4038755 c.1950G>T synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4038770 c.1935C>T synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4038773 c.1932T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4038782 c.1923G>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4038812 c.1893T>C synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4038845 c.1860G>C synonymous_variant 0.33 pyrazinamide Uncertain significance
clpC1 4038860 c.1845G>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.38 pyrazinamide Uncertain significance
clpC1 4038914 c.1791G>C synonymous_variant 0.41 pyrazinamide Uncertain significance
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.39 pyrazinamide Uncertain significance
clpC1 4038953 c.1752A>G synonymous_variant 0.35 pyrazinamide Uncertain significance
clpC1 4038956 c.1749T>C synonymous_variant 0.35 pyrazinamide Uncertain significance
clpC1 4038965 c.1740T>C synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4038971 c.1734T>C synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4038974 c.1731T>C synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.38 pyrazinamide Uncertain significance
clpC1 4038997 c.1708T>C synonymous_variant 0.32 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039022 c.1683A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039064 c.1641C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039097 c.1608G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039103 c.1602T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039106 c.1599G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039112 c.1593C>G synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039121 c.1584T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039142 c.1563A>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039145 c.1560G>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039169 p.Glu512Asp missense_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039172 c.1533A>G synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039178 c.1527G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039183 c.1522T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039186 c.1519C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039217 c.1488G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039226 c.1479T>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039286 c.1419T>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039295 c.1410A>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039319 c.1386T>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039328 c.1377A>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039331 c.1374C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039337 p.Thr456Gln missense_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039349 c.1356C>T synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039352 c.1353C>G synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039364 c.1341C>G synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039391 c.1314T>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039409 c.1296T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039412 c.1293T>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039415 p.Glu430Asp missense_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039442 c.1263A>G synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039448 c.1257A>G synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039466 c.1239T>C synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039469 c.1236T>C synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039481 c.1224T>C synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039484 c.1221T>C synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039517 c.1188C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039556 c.1149G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039559 c.1146C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039562 c.1143C>G synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039565 c.1140G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039570 p.Met379Leu missense_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039577 c.1128T>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039610 c.1095G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039616 c.1089G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039661 c.1044T>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039664 c.1041G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039682 c.1023C>T synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039694 c.1011G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039700 c.1005C>T synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4039724 c.981A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039751 c.954A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039757 c.948A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039781 c.924G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039790 c.915C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039817 c.888A>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039826 c.879C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039831 c.874T>C synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039850 c.855T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039865 c.840T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039952 c.753T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039982 c.723G>A synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039988 c.717C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039991 c.714G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039994 c.711G>A synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040021 c.684A>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040033 c.672G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040036 c.669C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4040105 c.600C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
panD 4045028 c.-747C>G upstream_gene_variant 0.17 pyrazinamide Uncertain significance
panD 4045034 c.-753A>C upstream_gene_variant 0.19 pyrazinamide Uncertain significance
panD 4045055 c.-774T>G upstream_gene_variant 0.2 pyrazinamide Uncertain significance
panD 4045067 c.-786C>G upstream_gene_variant 0.18 pyrazinamide Uncertain significance
glpK 4138565 c.1191G>C synonymous_variant 0.24 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138568 c.1188A>C synonymous_variant 0.22 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138571 c.1185C>G synonymous_variant 0.22 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138574 c.1182G>C synonymous_variant 0.22 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138580 c.1176C>T synonymous_variant 0.2 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138601 c.1155G>C synonymous_variant 0.25 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138606 c.1150T>C synonymous_variant 0.27 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138610 c.1146C>G synonymous_variant 0.27 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138622 c.1134C>G synonymous_variant 0.24 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138625 c.1131G>C synonymous_variant 0.23 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138634 c.1122G>A synonymous_variant 0.23 ethambutol Not assoc w R - Interim
isoniazid Not assoc w R - Interim
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
glpK 4138643 c.1113A>C synonymous_variant 0.23 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138646 c.1110G>C synonymous_variant 0.18 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4139126 c.630G>C synonymous_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4139137 p.Asp207Asn missense_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4139143 c.613T>C synonymous_variant 0.19 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4139165 c.591A>G synonymous_variant 0.21 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4139168 c.588T>C synonymous_variant 0.2 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4139177 c.579T>C synonymous_variant 0.24 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4139183 c.573T>C synonymous_variant 0.21 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4139186 c.570G>C synonymous_variant 0.2 ethambutol Not assoc w R - Interim
isoniazid Not assoc w R - Interim
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
glpK 4139195 c.561G>T synonymous_variant 0.21 ethambutol Not assoc w R - Interim
isoniazid Not assoc w R - Interim
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
glpK 4139198 c.558C>G synonymous_variant 0.19 ethambutol Not assoc w R - Interim
isoniazid Not assoc w R - Interim
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
glpK 4139207 c.549T>C synonymous_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
embC 4240726 c.864G>C synonymous_variant 0.16 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.24 ethambutol Uncertain significance
embC 4240783 c.921G>C synonymous_variant 0.24 ethambutol Uncertain significance
embC 4240789 c.927T>C synonymous_variant 0.22 ethambutol Uncertain significance
embC 4240819 c.957A>G synonymous_variant 0.24 ethambutol Uncertain significance
embC 4240831 c.969T>G synonymous_variant 0.23 ethambutol Uncertain significance
embC 4240867 c.1005T>C synonymous_variant 0.21 ethambutol Uncertain significance
embC 4240870 c.1008T>C synonymous_variant 0.21 ethambutol Uncertain significance
embC 4240873 c.1011C>G synonymous_variant 0.22 ethambutol Uncertain significance
embC 4240879 c.1017G>C synonymous_variant 0.22 ethambutol Uncertain significance
embC 4240880 p.Ala340Thr missense_variant 0.22 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.2 ethambutol Uncertain significance
embC 4241047 c.1185C>G synonymous_variant 0.16 ethambutol Uncertain significance
embC 4241050 c.1188T>G synonymous_variant 0.18 ethambutol Uncertain significance
embC 4241053 c.1191G>C synonymous_variant 0.19 ethambutol Uncertain significance
embC 4241089 c.1227C>G synonymous_variant 0.27 ethambutol Uncertain significance
embC 4241095 c.1233C>T synonymous_variant 0.23 ethambutol Uncertain significance
embC 4241107 c.1245G>C synonymous_variant 0.24 ethambutol Uncertain significance
embC 4241140 c.1278A>G synonymous_variant 0.15 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.18 ethambutol Uncertain significance
embC 4241453 p.Ile531Val missense_variant 0.18 ethambutol Uncertain significance
embC 4241587 c.1725C>G synonymous_variant 0.15 ethambutol Uncertain significance
embC 4241591 p.Leu577Val missense_variant 0.18 ethambutol Uncertain significance
embC 4241611 c.1749G>C synonymous_variant 0.18 ethambutol Uncertain significance
embC 4241614 c.1752A>C synonymous_variant 0.18 ethambutol Uncertain significance
embC 4241626 c.1764T>C synonymous_variant 0.21 ethambutol Uncertain significance
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4242742 c.-491C>G upstream_gene_variant 0.23 ethambutol Uncertain significance
embA 4242748 c.-485A>G upstream_gene_variant 0.22 ethambutol Uncertain significance
embA 4242754 c.-479G>C upstream_gene_variant 0.22 ethambutol Uncertain significance
embC 4242764 p.Val968Leu missense_variant 0.24 ethambutol Uncertain significance
embA 4242772 c.-461G>C upstream_gene_variant 0.26 ethambutol Uncertain significance
embC 4242803 p.Val981Leu missense_variant 0.76 ethambutol Not assoc w R
embA 4242820 c.-413G>C upstream_gene_variant 0.21 ethambutol Uncertain significance
embA 4242823 c.-410G>C upstream_gene_variant 0.2 ethambutol Uncertain significance
embA 4242832 c.-401A>C upstream_gene_variant 0.2 ethambutol Uncertain significance
embA 4242838 c.-395C>G upstream_gene_variant 0.2 ethambutol Uncertain significance
embC 4242841 c.2979C>T synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embA 4242844 c.-389A>G upstream_gene_variant 0.18 ethambutol Uncertain significance
embA 4242847 c.-386C>A upstream_gene_variant 0.18 ethambutol Uncertain significance
embA 4242859 c.-374C>T upstream_gene_variant 0.17 ethambutol Uncertain significance
embA 4242862 c.-371A>G upstream_gene_variant 0.17 ethambutol Uncertain significance
embC 4242863 p.Tyr1001Asn missense_variant 0.17 ethambutol Uncertain significance
embA 4245137 c.1905T>C synonymous_variant 0.23 ethambutol Uncertain significance
embA 4245146 c.1914G>A synonymous_variant 0.25 ethambutol Uncertain significance
embA 4245149 c.1917C>G synonymous_variant 0.23 ethambutol Uncertain significance
embA 4245153 p.Ile641Val missense_variant 0.22 ethambutol Uncertain significance
embA 4245182 c.1950T>C synonymous_variant 0.27 ethambutol Uncertain significance
embA 4245189 c.1957C>T synonymous_variant 0.27 ethambutol Uncertain significance
embA 4245198 p.Leu656Ile missense_variant 0.23 ethambutol Uncertain significance
embA 4245207 c.1975T>C synonymous_variant 0.2 ethambutol Uncertain significance
embA 4245215 c.1983A>C synonymous_variant 0.18 ethambutol Uncertain significance
embA 4245222 p.Tyr664Gln missense_variant 0.17 ethambutol Uncertain significance
embB 4246256 c.-258G>T upstream_gene_variant 0.17 ethambutol Uncertain significance
embB 4246259 c.-255G>C upstream_gene_variant 0.17 ethambutol Uncertain significance
embA 4246308 p.Thr1026Ala missense_variant 0.18 ethambutol Uncertain significance
embB 4246316 c.-198T>G upstream_gene_variant 0.18 ethambutol Uncertain significance
embB 4246319 c.-195G>C upstream_gene_variant 0.17 ethambutol Uncertain significance
embA 4246329 p.Thr1033Ala missense_variant 0.17 ethambutol Uncertain significance
embB 4247434 c.921C>G synonymous_variant 0.16 ethambutol Uncertain significance
embB 4247437 c.924A>G synonymous_variant 0.16 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.16 ethambutol Uncertain significance
embB 4247446 c.933C>T synonymous_variant 0.17 ethambutol Uncertain significance
embB 4247464 c.951C>G synonymous_variant 0.21 ethambutol Uncertain significance
embB 4247470 c.957T>C synonymous_variant 0.24 ethambutol Uncertain significance
embB 4247491 c.978G>C synonymous_variant 0.26 ethambutol Uncertain significance
embB 4247497 c.984T>C synonymous_variant 0.26 ethambutol Uncertain significance
embB 4247512 c.999T>C synonymous_variant 0.2 ethambutol Uncertain significance
embB 4247539 c.1026T>C synonymous_variant 0.19 ethambutol Uncertain significance
embB 4247554 c.1041T>C synonymous_variant 0.16 ethambutol Uncertain significance
embB 4247746 c.1233C>T synonymous_variant 0.18 ethambutol Uncertain significance
embB 4247761 c.1248T>C synonymous_variant 0.17 ethambutol Uncertain significance
embB 4247773 c.1260G>A synonymous_variant 0.19 ethambutol Uncertain significance
embB 4247776 c.1263G>T synonymous_variant 0.21 ethambutol Uncertain significance
embB 4247797 c.1284C>G synonymous_variant 0.22 ethambutol Uncertain significance
embB 4247800 c.1287A>T synonymous_variant 0.21 ethambutol Uncertain significance
embB 4247803 c.1290G>C synonymous_variant 0.21 ethambutol Uncertain significance
embB 4247815 c.1302C>G synonymous_variant 0.24 ethambutol Uncertain significance
embB 4247819 p.Val436Ile missense_variant 0.25 ethambutol Uncertain significance
embB 4247830 c.1317A>G synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embB 4247875 c.1362G>C synonymous_variant 0.22 ethambutol Uncertain significance
embB 4247876 c.1363C>T synonymous_variant 0.21 ethambutol Uncertain significance
embB 4247881 c.1368G>C synonymous_variant 0.22 ethambutol Uncertain significance
embB 4247887 c.1374C>T synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.24 ethambutol Uncertain significance
embB 4247899 p.Met462Ile missense_variant 0.29 ethambutol Uncertain significance
embB 4247905 c.1392G>C synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.28 ethambutol Uncertain significance
embB 4247914 c.1401G>C synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.22 ethambutol Uncertain significance
embB 4247940 p.Leu476Trp missense_variant 0.26 ethambutol Uncertain significance
embB 4248007 c.1494C>G synonymous_variant 0.17 ethambutol Uncertain significance
embB 4248011 p.Ser500Arg missense_variant 0.15 ethambutol Uncertain significance
embB 4248014 p.Thr501Ala missense_variant 0.16 ethambutol Uncertain significance
embB 4248070 c.1557T>C synonymous_variant 0.15 ethambutol Uncertain significance
embB 4248085 c.1572T>C synonymous_variant 0.16 ethambutol Uncertain significance
embB 4248097 c.1584C>G synonymous_variant 0.17 ethambutol Uncertain significance
embB 4248130 c.1617G>C synonymous_variant 0.2 ethambutol Uncertain significance
embB 4248133 c.1620C>G synonymous_variant 0.2 ethambutol Uncertain significance
embB 4248139 c.1626C>G synonymous_variant 0.2 ethambutol Uncertain significance
embB 4248142 c.1629T>C synonymous_variant 0.2 ethambutol Uncertain significance
embB 4248143 c.1630T>C synonymous_variant 0.2 ethambutol Uncertain significance
embB 4248157 c.1644A>G synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.21 ethambutol Uncertain significance
embB 4248304 c.1791G>C synonymous_variant 0.25 ethambutol Uncertain significance
embB 4248316 c.1803C>G synonymous_variant 0.27 ethambutol Uncertain significance
embB 4248319 c.1806A>G synonymous_variant 0.27 ethambutol Uncertain significance
embB 4248343 c.1830G>C synonymous_variant 0.24 ethambutol Uncertain significance
embB 4248373 c.1860C>G synonymous_variant 0.15 ethambutol Uncertain significance
embB 4249469 p.Leu986Met missense_variant 0.25 ethambutol Uncertain significance
embB 4249486 c.2973T>G synonymous_variant 0.26 ethambutol Uncertain significance
embB 4249498 c.2985G>C synonymous_variant 0.27 ethambutol Uncertain significance
embB 4249521 p.Ala1003Val missense_variant 0.27 ethambutol Uncertain significance
embB 4249525 c.3012T>C synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.27 ethambutol Uncertain significance
embB 4249532 p.Ala1007Thr missense_variant 0.27 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.29 ethambutol Uncertain significance
embB 4249543 c.3030G>C synonymous_variant 0.31 ethambutol Uncertain significance
embB 4249546 c.3033G>A synonymous_variant 0.29 ethambutol Uncertain significance
embB 4249558 c.3045A>C synonymous_variant 0.24 ethambutol Uncertain significance
embB 4249568 p.Ser1019Thr missense_variant 0.19 ethambutol Uncertain significance
aftB 4267091 c.1746C>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance