TB-Profiler result

Run: ERR4815752
Summary

Run ID: ERR4815752

Sample name:

Date: 2024-10-04T09:16:39.284107

Number of reads: 3218803

Percentage reads mapped: 76.09

Median coverage: 87.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.1
lineage4 Euro-American None 0.95
lineage4.9 Euro-American (H37Rv-like) None 0.96
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 1236 c.1236C>T synonymous_variant 0.14 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.15 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.17 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.19 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.17 isoniazid
gyrB 6319 c.1080G>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.17 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7084 c.-218A>G upstream_gene_variant 0.17 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrA 7093 c.-209T>G upstream_gene_variant 0.17 levofloxacin
moxifloxacin
gyrA 7099 c.-203G>A upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Thr missense_variant 0.2 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7427 c.126G>C synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.21 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7562 c.261C>T synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 7571 c.270G>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 0.22 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7625 c.324G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCGC synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 7697 c.396C>A synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8553 c.1252C>A synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8708 c.1407G>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.17 levofloxacin
moxifloxacin
gyrA 8891 c.1590G>A synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8966 c.1665C>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.19 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>A synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 0.18 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.16 levofloxacin
moxifloxacin
fgd1 491130 c.348C>G synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fgd1 491151 c.369G>A synonymous_variant 0.15 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 0.16 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.16 pretomanid
delamanid
clofazimine
mshA 575809 c.462C>T synonymous_variant 0.21 isoniazid
ethionamide
mshA 575812 c.465C>T synonymous_variant 0.22 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.26 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 0.27 isoniazid
ethionamide
mshA 575830 c.483C>G synonymous_variant 0.27 isoniazid
ethionamide
mshA 575833 c.486C>G synonymous_variant 0.28 isoniazid
ethionamide
mshA 575845 c.498C>T synonymous_variant 0.33 isoniazid Not assoc w R - Interim
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.28 isoniazid
ethionamide
mshA 575887 c.540G>C synonymous_variant 0.28 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.28 isoniazid
ethionamide
mshA 575896 c.549G>C synonymous_variant 0.28 isoniazid
ethionamide
mshA 575908 c.561A>G synonymous_variant 0.26 isoniazid
ethionamide
mshA 575917 p.Asp190Glu missense_variant 0.22 isoniazid
ethionamide
mshA 575920 c.573C>G synonymous_variant 0.22 isoniazid
ethionamide
mshA 575924 p.Gly193Ser missense_variant 0.21 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.19 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.17 isoniazid
ethionamide
ccsA 620288 p.Arg133Gln missense_variant 0.14 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>T synonymous_variant 0.16 kanamycin
capreomycin
amikacin
ccsA 620310 c.420C>T synonymous_variant 0.18 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.16 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.19 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.19 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.18 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.18 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.18 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.18 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620389 c.499C>T synonymous_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>A synonymous_variant 0.16 kanamycin
capreomycin
amikacin
ccsA 620763 c.873G>A synonymous_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620769 c.879C>G synonymous_variant 0.17 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.16 kanamycin
capreomycin
amikacin
hadA 731792 c.-138G>A upstream_gene_variant 0.2 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.18 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.2 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.18 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.18 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.19 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.2 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.21 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.21 isoniazid
nusG 734451 c.198G>C synonymous_variant 0.15 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.16 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.18 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.15 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.15 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.16 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.19 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.19 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.21 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.21 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.25 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.27 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.27 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.3 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.3 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.18 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.14 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.21 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.23 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.24 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.2 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.24 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.25 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.2 rifampicin
rpoB 761312 c.1506G>C synonymous_variant 0.2 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.16 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.16 rifampicin
rpoB 761773 p.His656Pro missense_variant 0.15 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.16 rifampicin
rpoB 761815 p.Ala670Asp missense_variant 0.14 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.14 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.13 rifampicin
rpoB 762065 c.2259T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.16 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.18 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.17 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.17 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.16 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.2 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.2 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.2 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.19 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.23 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.21 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.21 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.19 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.16 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.16 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.23 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.23 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.24 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.27 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.26 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.22 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.21 rifampicin Uncertain significance
rpoC 762521 c.-849C>T upstream_gene_variant 0.23 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.19 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.18 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.18 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.18 rifampicin
rpoB 762926 c.3120C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.2 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.21 rifampicin
rpoC 763025 c.-345C>T upstream_gene_variant 0.21 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.18 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.19 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.15 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.19 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.24 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.36 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.22 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.22 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.2 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.19 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.21 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.21 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.23 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.21 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.24 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.25 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.25 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.23 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.25 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.23 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.23 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.22 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 0.15 rifampicin
rpoC 763963 c.594C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.18 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.16 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.17 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.2 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.17 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.16 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.15 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.14 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.16 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764112 p.Tyr248Phe missense_variant 0.14 rifampicin
rpoC 764215 c.846A>G synonymous_variant 0.18 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.24 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.28 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.28 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.29 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.18 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.15 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.24 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.19 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.2 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.19 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.23 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.15 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.23 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.15 rifampicin
rpoC 764995 c.1626C>G synonymous_variant 0.17 rifampicin Not assoc w R
rpoC 765019 c.1650A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.17 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.16 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765079 c.1710T>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.16 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.21 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.23 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.26 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.34 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.32 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.31 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.3 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.3 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.28 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.25 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.36 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.21 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.21 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.21 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.16 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.17 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.16 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.16 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.18 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.18 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.29 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.26 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.28 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.3 rifampicin
rpoC 766030 c.2661C>G synonymous_variant 0.29 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.26 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.27 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.17 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.17 rifampicin
rpoC 766357 c.2988C>T synonymous_variant 0.15 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.15 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.17 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.18 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.19 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.18 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.18 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.17 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.16 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.17 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.21 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.23 rifampicin
rpoC 766660 c.3291G>C synonymous_variant 0.2 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.22 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.21 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.21 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.24 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.25 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.22 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.22 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.23 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.23 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.24 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.3 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.34 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.3 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.31 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.33 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.27 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.23 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.19 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.16 rifampicin
mmpL5 776030 c.2451G>A synonymous_variant 0.17 bedaquiline
clofazimine
rpsL 781649 c.90T>C synonymous_variant 0.15 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.17 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.18 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.18 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.18 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.18 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.17 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.15 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.16 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.19 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.19 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.18 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.18 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.18 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.17 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.17 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.21 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.17 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.16 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.17 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.17 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.19 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.19 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.2 streptomycin Uncertain significance
rplC 800627 c.-182C>T upstream_gene_variant 0.15 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.18 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.17 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.21 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.23 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.24 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.24 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.25 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.23 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.18 linezolid
rplC 801276 c.468G>C synonymous_variant 0.16 linezolid
rplC 801282 c.474G>C synonymous_variant 0.15 linezolid
rplC 801309 c.501C>G synonymous_variant 0.17 linezolid
rplC 801312 c.504G>C synonymous_variant 0.18 linezolid
rplC 801321 c.513C>T synonymous_variant 0.19 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.18 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.15 linezolid
rplC 801423 c.615G>C synonymous_variant 0.17 linezolid
rplC 801426 c.618C>G synonymous_variant 0.16 linezolid
rplC 801427 p.Met207Val missense_variant 0.17 linezolid
rplC 801438 c.630T>C synonymous_variant 0.18 linezolid
rplC 801442 p.Ile212Val missense_variant 0.18 linezolid
fbiC 1303590 c.660A>G synonymous_variant 0.14 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fbiC 1304727 c.1797A>G synonymous_variant 0.15 pretomanid
delamanid
clofazimine
fbiC 1304739 c.1809C>T synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 0.39 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304862 c.1932G>A synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304883 p.Glu651Asp missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304891 p.Ile654Thr missense_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304907 c.1977C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1304983 c.2053C>T synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 0.16 pretomanid
delamanid
clofazimine
sigE 1364847 c.435G>C synonymous_variant 0.17 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.18 pyrazinamide
sigE 1364862 c.450C>A synonymous_variant 0.18 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.19 pyrazinamide
sigE 1364868 c.456T>G synonymous_variant 0.2 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.23 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.24 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.2 pyrazinamide
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.15 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.15 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.25 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.25 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.25 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.24 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.3 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.31 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.29 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.36 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 0.61 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.16 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.22 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.42 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.62 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.33 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.32 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
inhA 1674537 c.336C>G synonymous_variant 0.17 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.15 isoniazid
ethionamide
rpsA 1833568 c.27G>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.19 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.2 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.17 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.16 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.16 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.17 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.16 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.21 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.24 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.26 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.25 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.23 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.21 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.19 pyrazinamide
rpsA 1834081 c.540C>T synonymous_variant 0.18 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.17 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.18 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.19 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.18 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.2 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.2 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.18 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.17 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.24 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.27 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.28 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.31 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.27 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.26 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.27 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.27 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.27 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.22 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.21 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.19 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.19 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.19 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.22 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.22 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.19 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.19 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.18 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.17 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.26 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.25 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.3 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.28 linezolid
tsnR 1853423 c.-183C>T upstream_gene_variant 0.15 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.16 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.16 linezolid
tlyA 1918002 c.63A>G synonymous_variant 0.19 capreomycin
ndh 2101830 p.Ile405Val missense_variant 0.17 isoniazid
delamanid
ethionamide
ndh 2101838 p.Ala402Val missense_variant 0.17 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
kasA 2517950 c.-165C>G upstream_gene_variant 0.17 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.15 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.21 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.2 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.19 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.24 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.21 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.19 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.17 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.16 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.16 isoniazid
ahpC 2726591 c.399C>G synonymous_variant 0.16 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.16 isoniazid
folC 2747343 p.Val86Ile missense_variant 0.14 para-aminosalicylic_acid
Rv2477c 2782912 p.Ser377Thr missense_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782928 p.Thr372Glu missense_variant 0.15 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.15 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.17 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.26 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.2 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783048 p.Asp332Gly missense_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.16 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.16 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.16 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.15 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.15 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.22 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.2 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.21 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
thyX 3067316 c.630A>G synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.17 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067376 c.570G>A synonymous_variant 0.17 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.2 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.18 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.18 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.18 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.18 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.17 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.17 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.15 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.15 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.15 para-aminosalicylic_acid
thyX 3067691 p.Ile85Met missense_variant 0.16 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.15 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.17 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.17 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.16 para-aminosalicylic_acid
thyX 3067762 c.184C>A synonymous_variant 0.14 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.14 para-aminosalicylic_acid
thyX 3067781 c.165C>A synonymous_variant 0.15 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.16 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.16 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.16 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.17 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.17 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.16 para-aminosalicylic_acid
lpqB 3624077 c.834G>A synonymous_variant 0.14 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625510 c.-600T>C upstream_gene_variant 0.16 rifampicin
bedaquiline
lpqB 3625513 c.-603G>C upstream_gene_variant 0.17 rifampicin
bedaquiline
lpqB 3625518 c.-608T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625525 c.-615G>C upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625528 c.-618G>T upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 0.2 rifampicin
bedaquiline
lpqB 3625549 c.-639G>A upstream_gene_variant 0.18 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.18 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.17 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.18 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.18 rifampicin
bedaquiline
mtrB 3625616 p.Arg333Ala missense_variant 0.18 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.17 rifampicin
bedaquiline
mtrB 3625636 c.978C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625669 c.-759G>C upstream_gene_variant 0.16 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.21 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.2 rifampicin
bedaquiline
lpqB 3625696 c.-786A>G upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrB 3625705 c.909C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625714 c.-804C>T upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625735 c.-825C>T upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625749 c.-839C>T upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3625750 c.864G>A synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.31 rifampicin Uncertain significance
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625797 p.Val273Met missense_variant 0.31 rifampicin Uncertain significance
bedaquiline Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625849 c.-939T>C upstream_gene_variant 0.15 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrA 3626723 c.627C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.15 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.15 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.17 rifampicin
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.18 rifampicin
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626840 c.-227C>G upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.17 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626912 c.-299T>G upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrB 3626927 c.-314G>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrA 3626939 c.411A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 0.18 rifampicin
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 0.17 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrA 3627299 c.51G>A synonymous_variant 0.14 rifampicin Not assoc w R - Interim
bedaquiline
rpoA 3877515 c.993G>C synonymous_variant 0.15 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.23 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.23 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.29 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.18 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.19 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.2 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.22 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.25 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.24 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.2 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.19 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.19 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.19 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.19 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.22 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.18 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.16 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.2 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.19 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.18 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>A synonymous_variant 0.17 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.14 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.17 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.16 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.16 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.21 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.19 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.19 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.19 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.18 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.16 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.16 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.16 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.19 rifampicin
rpoA 3878716 c.-209C>G upstream_gene_variant 0.14 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.15 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.15 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.15 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.19 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.19 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.23 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.22 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.21 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.2 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.21 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.22 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.18 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.18 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.24 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 0.22 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.17 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.17 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 0.16 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.17 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.17 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.18 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.23 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.21 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.23 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.23 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.23 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.23 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.21 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.17 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.17 rifampicin
clpC1 4038530 p.Glu725Asp missense_variant 0.14 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.18 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.18 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.15 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.16 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4038749 c.1956C>G synonymous_variant 0.2 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.2 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.2 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.2 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.19 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.18 pyrazinamide
clpC1 4038821 c.1884G>A synonymous_variant 0.18 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.25 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.26 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.24 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.22 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.22 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.19 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.18 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.21 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.21 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.21 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.21 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.2 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.18 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.17 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.16 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.18 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.16 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.17 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.15 pyrazinamide
clpC1 4039625 c.1080G>A synonymous_variant 0.16 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.14 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.17 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.17 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.16 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.16 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.18 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.21 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.22 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.21 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.23 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.2 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.23 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.28 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.23 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.24 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.23 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.21 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.19 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.18 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.21 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.21 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.19 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.17 pyrazinamide
clpC1 4040105 c.600C>G synonymous_variant 0.16 pyrazinamide
clpC1 4040501 c.204C>T synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
panD 4044800 c.-519C>G upstream_gene_variant 0.16 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.15 pyrazinamide
glpK 4138654 c.1102C>T synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138681 p.Met359Val missense_variant 0.17 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138695 p.Pro354Asp missense_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138721 c.1035G>A synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>G synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138763 c.993G>A synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138769 c.987G>C synonymous_variant 0.16 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138774 p.Ser328Ala missense_variant 0.16 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139474 c.282T>C synonymous_variant 0.16 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139477 c.279A>G synonymous_variant 0.16 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139483 c.273C>G synonymous_variant 0.16 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139486 c.270T>C synonymous_variant 0.16 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139489 c.267G>T synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139494 c.262T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139504 p.Asp84Asn missense_variant 0.18 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139515 p.Ser81Ala missense_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139516 c.240A>G synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139524 p.Thr78Ala missense_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol
glpK 4139526 p.Ala77Arg missense_variant 0.21 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139537 c.219G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139541 p.Ile72Thr missense_variant 0.25 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139545 c.211T>C synonymous_variant 0.24 levofloxacin
moxifloxacin Not assoc w R - Interim
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139552 p.Ala68Ser missense_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139561 c.195G>A synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139581 p.Asn59Asp missense_variant 0.25 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4139588 c.168G>C synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139597 c.159C>G synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139601 p.Arg52Gln missense_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139611 p.Ile49Val missense_variant 0.26 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139615 c.141G>A synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
embC 4240819 c.957A>G synonymous_variant 0.16 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.16 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.15 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.16 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.18 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.18 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.16 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.16 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.16 ethambutol
embC 4241170 c.1308G>C synonymous_variant 0.16 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.16 ethambutol
embA 4244582 c.1350T>C synonymous_variant 0.19 ethambutol
embA 4244611 p.Ala460Gly missense_variant 0.15 ethambutol
embA 4245083 c.1851A>C synonymous_variant 0.18 ethambutol
embA 4245089 c.1857G>C synonymous_variant 0.2 ethambutol
embA 4245092 c.1860C>G synonymous_variant 0.21 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.23 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.23 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.22 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.24 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.22 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.21 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.18 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.17 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.15 ethambutol
embA 4245222 p.Tyr664His missense_variant 0.14 ethambutol Uncertain significance
embB 4247470 c.957T>C synonymous_variant 0.19 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.2 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.19 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.18 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.15 ethambutol
embB 4247866 c.1353G>C synonymous_variant 0.19 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.19 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.19 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.18 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.2 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.19 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.2 ethambutol
embB 4247932 c.1419C>G synonymous_variant 0.2 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.17 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.19 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.19 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.2 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.15 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.16 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.15 ethambutol Uncertain significance
embB 4248070 c.1557T>C synonymous_variant 0.15 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.17 ethambutol Not assoc w R - Interim
embB 4248199 c.1686A>G synonymous_variant 0.17 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.17 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.16 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.16 ethambutol Uncertain significance
embB 4248220 c.1707A>C synonymous_variant 0.22 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.23 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.22 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.25 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.23 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.23 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.17 ethambutol
embB 4248361 c.1848A>C synonymous_variant 0.16 ethambutol
embB 4248362 p.Ser617Ala missense_variant 0.16 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.16 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.18 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.16 ethambutol