Run ID: ERR4815752
Sample name:
Date: 2024-10-04T09:16:39.284107
Number of reads: 3218803
Percentage reads mapped: 76.09
Median coverage: 87.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
La1.2.BCG | M.bovis | None | 0.1 |
lineage4 | Euro-American | None | 0.95 |
lineage4.9 | Euro-American (H37Rv-like) | None | 0.96 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.61 | streptomycin | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.14 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.15 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.17 | isoniazid | |
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6763 | c.1524G>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7093 | c.-209T>G | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7124 | p.Ser629Thr | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7514 | c.213C>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>A | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7562 | c.261C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 0.22 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7625 | c.324G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382_384delAGGinsCGC | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>A | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8553 | c.1252C>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8696 | c.1395G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8708 | c.1407G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8731 | p.Gly477Ala | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8891 | c.1590G>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.17 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
fgd1 | 491130 | c.348C>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491151 | c.369G>A | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
mshA | 575809 | c.462C>T | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
mshA | 575833 | c.486C>G | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575845 | c.498C>T | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575887 | c.540G>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575896 | c.549G>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575908 | c.561A>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575917 | p.Asp190Glu | missense_variant | 0.22 | isoniazid | |
ethionamide | ||||||
mshA | 575920 | c.573C>G | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
mshA | 575924 | p.Gly193Ser | missense_variant | 0.21 | isoniazid | |
ethionamide | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
mshA | 575950 | c.603C>G | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.14 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620295 | c.405G>T | synonymous_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620310 | c.420C>T | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620317 | p.Val143Leu | missense_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620763 | c.873G>A | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620769 | c.879C>G | synonymous_variant | 0.17 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.18 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.2 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.18 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.18 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.19 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.2 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.21 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.21 | isoniazid | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.15 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.16 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.18 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.15 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.15 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.27 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.27 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>T | synonymous_variant | 0.14 | rifampicin | |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761773 | p.His656Pro | missense_variant | 0.15 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.16 | rifampicin | |
rpoB | 761815 | p.Ala670Asp | missense_variant | 0.14 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.13 | rifampicin | |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.16 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.18 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.16 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.21 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.26 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoB | 762926 | c.3120C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 763025 | c.-345C>T | upstream_gene_variant | 0.21 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.15 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.21 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.24 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.25 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.23 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763963 | c.594C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763991 | p.Ile208Leu | missense_variant | 0.16 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.16 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.14 | rifampicin | |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.23 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.28 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.25 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766030 | c.2661C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.26 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.17 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.15 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.17 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766660 | c.3291G>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.21 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 766882 | c.3513C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.3 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.33 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.27 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.23 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.19 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.16 | rifampicin | |
mmpL5 | 776030 | c.2451G>A | synonymous_variant | 0.17 | bedaquiline | |
clofazimine | ||||||
rpsL | 781649 | c.90T>C | synonymous_variant | 0.15 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.15 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.2 | streptomycin | Uncertain significance |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.15 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.18 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.18 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.16 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.15 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.17 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.19 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.15 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.17 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.16 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.17 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.18 | linezolid | |
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.14 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304739 | c.1809C>T | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.39 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304862 | c.1932G>A | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
sigE | 1364847 | c.435G>C | synonymous_variant | 0.17 | pyrazinamide | |
sigE | 1364856 | c.444C>G | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364862 | c.450C>A | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1364868 | c.456T>G | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364887 | c.475_477delTTAinsCTG | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364898 | c.486C>T | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364904 | p.Asp164Glu | missense_variant | 0.2 | pyrazinamide | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.15 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.15 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.25 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.25 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.24 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.3 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472045 | n.200T>A | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.36 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472300 | n.455C>T | non_coding_transcript_exon_variant | 0.61 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.16 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 0.51 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.74 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.62 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.15 | isoniazid | |
ethionamide | ||||||
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834081 | c.540C>T | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834618 | c.1077G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.19 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.22 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.19 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.18 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.17 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.26 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.25 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.3 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853423 | c.-183C>T | upstream_gene_variant | 0.15 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.16 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.16 | linezolid | |
tlyA | 1918002 | c.63A>G | synonymous_variant | 0.19 | capreomycin | |
ndh | 2101830 | p.Ile405Val | missense_variant | 0.17 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101838 | p.Ala402Val | missense_variant | 0.17 | isoniazid | Uncertain significance |
delamanid | ||||||
ethionamide | Uncertain significance | |||||
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.17 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.15 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.16 | isoniazid | |
ahpC | 2726591 | c.399C>G | synonymous_variant | 0.16 | isoniazid | |
ahpC | 2726593 | p.Val134Ala | missense_variant | 0.16 | isoniazid | |
folC | 2747343 | p.Val86Ile | missense_variant | 0.14 | para-aminosalicylic_acid | |
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782928 | p.Thr372Glu | missense_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.17 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.26 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.2 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.15 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.22 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.2 | kanamycin | Not assoc w R - Interim |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.21 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
thyX | 3067316 | c.630A>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067325 | c.621A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067376 | c.570G>A | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067490 | c.456C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067556 | p.His130Gln | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067559 | c.387C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067565 | p.Asp127Glu | missense_variant | 0.15 | para-aminosalicylic_acid | |
thyX | 3067570 | p.Ala126Pro | missense_variant | 0.15 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyX | 3067691 | p.Ile85Met | missense_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067762 | c.184C>A | synonymous_variant | 0.14 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.14 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>A | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3073898 | p.Ala192Ser | missense_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3073917 | c.555C>G | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3073920 | c.552C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
lpqB | 3624077 | c.834G>A | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625510 | c.-600T>C | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625513 | c.-603G>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625525 | c.-615G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625549 | c.-639G>A | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.31 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.31 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627299 | c.51G>A | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
rpoA | 3877515 | c.993G>C | synonymous_variant | 0.15 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.23 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.23 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.29 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.19 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3877890 | c.618C>T | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.19 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.22 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3877923 | c.585C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878043 | c.465G>A | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878364 | c.144A>T | synonymous_variant | 0.14 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878424 | c.84G>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.16 | rifampicin | |
rpoA | 3878484 | c.24C>A | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3878490 | c.18C>A | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3878496 | c.12A>T | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.14 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.15 | rifampicin | |
rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.15 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.15 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.19 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.2 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3878860 | c.-353C>T | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.19 | rifampicin | Uncertain significance |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.16 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.17 | rifampicin | Uncertain significance |
rpoA | 3878938 | c.-431T>A | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.17 | rifampicin | Uncertain significance |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.17 | rifampicin | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.14 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.18 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.15 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038749 | c.1956C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038821 | c.1884G>A | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.17 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.17 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039625 | c.1080G>A | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040501 | c.204C>T | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
panD | 4044800 | c.-519C>G | upstream_gene_variant | 0.16 | pyrazinamide | |
panD | 4044812 | c.-531A>C | upstream_gene_variant | 0.15 | pyrazinamide | |
glpK | 4138654 | c.1102C>T | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138681 | p.Met359Val | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138721 | c.1035G>A | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138730 | c.1026C>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138757 | c.999A>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138763 | c.993G>A | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138769 | c.987G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138774 | p.Ser328Ala | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139474 | c.282T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139477 | c.279A>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139483 | c.273C>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139486 | c.270T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139489 | c.267G>T | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139494 | c.262T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139504 | p.Asp84Asn | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139515 | p.Ser81Ala | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139516 | c.240A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139524 | p.Thr78Ala | missense_variant | 0.2 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | ||||||
glpK | 4139526 | p.Ala77Arg | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139537 | c.219G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139541 | p.Ile72Thr | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139545 | c.211T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139552 | p.Ala68Ser | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139561 | c.195G>A | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139581 | p.Asn59Asp | missense_variant | 0.25 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
glpK | 4139588 | c.168G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139597 | c.159C>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139601 | p.Arg52Gln | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139611 | p.Ile49Val | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139615 | c.141G>A | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
embC | 4240819 | c.957A>G | synonymous_variant | 0.16 | ethambutol | |
embC | 4240828 | c.966G>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.15 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.16 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.18 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.18 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.16 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4241170 | c.1308G>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4241173 | c.1311C>T | synonymous_variant | 0.16 | ethambutol | |
embA | 4244582 | c.1350T>C | synonymous_variant | 0.19 | ethambutol | |
embA | 4244611 | p.Ala460Gly | missense_variant | 0.15 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 0.18 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.2 | ethambutol | |
embA | 4245092 | c.1860C>G | synonymous_variant | 0.21 | ethambutol | |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 0.22 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.24 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.22 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.21 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 0.18 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.17 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.15 | ethambutol | |
embA | 4245222 | p.Tyr664His | missense_variant | 0.14 | ethambutol | Uncertain significance |
embB | 4247470 | c.957T>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.15 | ethambutol | |
embB | 4247866 | c.1353G>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4247875 | c.1362G>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4247876 | c.1363C>T | synonymous_variant | 0.19 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embB | 4247893 | c.1380C>T | synonymous_variant | 0.2 | ethambutol | |
embB | 4247899 | p.Met462Ile | missense_variant | 0.19 | ethambutol | |
embB | 4247905 | c.1392G>C | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embB | 4247909 | c.1396T>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4247932 | c.1419C>G | synonymous_variant | 0.2 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 0.17 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 0.19 | ethambutol | |
embB | 4247956 | c.1443G>C | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
embB | 4247974 | c.1461C>G | synonymous_variant | 0.2 | ethambutol | |
embB | 4248014 | p.Thr501Ala | missense_variant | 0.15 | ethambutol | Uncertain significance |
embB | 4248035 | p.Val508Ile | missense_variant | 0.16 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.15 | ethambutol | Uncertain significance |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.15 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.17 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.17 | ethambutol | |
embB | 4248205 | c.1692C>G | synonymous_variant | 0.16 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.16 | ethambutol | Uncertain significance |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4248304 | c.1791G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.22 | ethambutol | |
embB | 4248343 | c.1830G>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4248350 | c.1837T>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4248355 | c.1842A>G | synonymous_variant | 0.23 | ethambutol | |
embB | 4248358 | c.1845C>G | synonymous_variant | 0.17 | ethambutol | |
embB | 4248361 | c.1848A>C | synonymous_variant | 0.16 | ethambutol | |
embB | 4248362 | p.Ser617Ala | missense_variant | 0.16 | ethambutol | |
embB | 4248373 | c.1860C>G | synonymous_variant | 0.16 | ethambutol | |
embB | 4248386 | c.1873C>A | synonymous_variant | 0.18 | ethambutol | |
aftB | 4268205 | p.Val211Ala | missense_variant | 0.16 | ethambutol |